Skocz do pozycji: 1.

Tytuł:

The role of additional correction methods of insufficient adherence to treatment for effective blood pressure control in patients with resistant arterial hypertension

Autorzy:

Voloshyna, O.
Zbitnieva, V.
Busel, S.
Chaika, A.
Samorukova, V.
Dychko, T.

Powiązania:

https://bibliotekanauki.pl/articles/765449.pdf

Data publikacji:

2016

Wydawca:

Uniwersytet Mikołaja Kopernika w Toruniu. Wydział Nauk o Ziemi i Gospodarki Przestrzennej. Katedra Kultury Fizycznej

Tematy:

resistant hypertension, pseudo-resistant hypertension, uncontrolled blood pressure, adherence

Opis:

Voloshyna O., Zbitnieva V., Busel S., Chaika A., Samorukova V., Dychko T. The role of additional correction methods of insufficient adherence to treatment for effective blood pressure control in patients with resistant arterial hypertension. Journal of Education, Health and Sport. 2016;6(12):857-865. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.252818http://ojs.ukw.edu.pl/index.php/johs/article/view/4184   The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 754 (09.12.2016).754 Journal of Education, Health and Sport eISSN 2391-8306 7© The Author (s) 2016;This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercialuse, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper.Received: 05.12.2016. Revised 20.12.2016. Accepted: 25.12.2016. УДК 616.12-008.331.1-036.8 THE ROLE OF ADDITIONAL CORRECTION METHODS OF INSUFFICIENT ADHERENCE TO TREATMENT FOR EFFECTIVE BLOOD PRESSURE CONTROL IN PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION O. Voloshyna, V. Zbitnieva, S. Busel, A. Chaika, V. Samorukova, T. Dychko Odessa National Medical University, Ukraine AbstractThe article considers the results of applying the different correction methods of insufficient adherence to treatment in patients with resistant and pseudo-resistant arterial hypertension on the background of the optimization of antihypertensive therapy in the effective blood pressure control by a doctor and a patient.Keywords: resistant hypertension, pseudo-resistant hypertension, uncontrolled blood pressure, adherence

Źródło:

Journal of Education, Health and Sport; 2016, 6, 12
2391-8306

Pojawia się w:

Journal of Education, Health and Sport

Dostawca treści:

Biblioteka Nauki

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Tytuł:

Dietary resistant dextrins positively modulate fecal and cecal microbiota composition in young rats

Autorzy:

Śliżewska, Katarzyna
Libudzisz, Zdzisława
Barczyńska, Renata
Kapuśniak, Janusz
Zduńczyk, Zenon
Juśkiewicz, Jerzy

Powiązania:

https://bibliotekanauki.pl/articles/1038883.pdf

Data publikacji:

2015

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

resistant dextrin
microflora
rats

Opis:

The objective of the present study was to demonstrate the effect of dietary resistant dextrins, as potential prebiotics, on the intestinal microflora of young rats. Enzyme-resistant dextrin, prepared by heating of potato starch in the presence of hydrochloric (0.1% dsb) and tartaric (40% dsb) acid at 130ºC for 2 h (CA-dextrin). The experiment was performed on 24 Wistar male rats at 3-wk of age, divided by analogues in three experimental groups (control, starch and dextrin). Analyses determined the overall bacterial counts and the counts of Lactobacillus, Bifidobacterium, Bacteroides and Clostridium strains within the feces and cecal contents of rats using fluorescence in situ hybridization method. CA-dextrin had no effect on primary growth indicators (body weight, body weight gain, dietary consumption) or the mass of the small intestine and the cecum, but dextrins caused a reduction in pH and the concentration of ammonia within the cecal contents. That supplementation of diet with resistant dextrins had a positive effect on composition of intestinal microflora in rats. It increased the counts of Bifidobacterium and Lactobacillus strains both in the feces and in the cecum. Moreover, it reduced the counts of Clostridium and Bacteroides strains. These results may suggest that resistant dextrins exerted a prebiotic-like effect in the large intestine.

Źródło:

Acta Biochimica Polonica; 2015, 62, 4; 677-681
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 3.

Tytuł:

The citric acid-modified, enzyme-resistant dextrin from potato starch as a potential prebiotic

Autorzy:

Śliżewska, Katarzyna

Powiązania:

https://bibliotekanauki.pl/articles/1039464.pdf

Data publikacji:

2013

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

resistant dextrin
prebiotic
intestinal bacteria

Opis:

In the present study, enzyme-resistant dextrin, prepared by heating of potato starch in the presence of hydrochloric (0.1% dsb) and citric (0.1% dsb) acid at 130ºC for 3 h (CA-dextrin), was tested as a source of carbon for probiotic lactobacilli and bifidobacteria cultured with intestinal bacteria isolated from feces of three healthy 70-year old volunteers. The dynamics of growth of bacterial monocultures in broth containing citric acid (CA)-modified dextrin were estimated. It was also investigated whether lactobacilli and bifidobacteria cultured with intestinal bacteria in the presence of resistant dextrin would be able to dominate the intestinal isolates. Prebiotic fermentation of resistant dextrin was analyzed using prebiotic index (PI). In co-cultures of intestinal and probiotic bacteria, the environment was found to be dominated by the probiotic strains of Bifidobacterium and Lactobacillus, which is a beneficial effect.

Źródło:

Acta Biochimica Polonica; 2013, 60, 4; 671-675
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 4.

Tytuł:

Projektowanie włóknistych wyrobów nietkanych, przeznaczonych na warstwy przeciwuderzeniowe
Developing the non-woven, fibrous goods dedicated for impact-resistant layers

Autorzy:

Maklewska, E.

Powiązania:

https://bibliotekanauki.pl/articles/238069.pdf

Data publikacji:

2008

Wydawca:

Instytut Technologii Bezpieczeństwa Moratex

Tematy:

warstwa przeciwuderzeniowa
ochraniacze przeciwuderzeniowe
włókno kokosowe
impact-resistant layer
impact-resistant protectors
coconut fibres

Opis:

W wyniku pracy badawczej opracowano materiał włóknisty, o strukturze przestrzennej, przeznaczony na warstwy przeciwuderzeniowe w ochraniaczach stosowanych w ubiorach i wyposażeniu ochronnym osób uprawiających sporty urazogenne. Materiał otrzymano w wyniku nowatorskiego zastosowania proekologicznych włókien kokosowych, o dużej zawartości lignin oraz środka wiążącego z udziałem kopolimeru etylenu i octanu winylu z dodatkiem środków porotwórczych. Opracowany materiał został zgłoszony pod nazwą Impactex w 2005 r. do Urzędu Patentowego jako projekt wynalazczy nr P-374169. Jego skuteczność w zakresie tłumienia energii uderzenia potwierdziły rezultaty badań przeprowadzonych na stanowisku, służącym do oceny zdolności amortyzacji uderzenia ochraniaczy sportowych. Oryginalna konstrukcja stanowiska umożliwia taka ocenę przy jednoczesnym zastosowaniu dwóch metod badawczych. Została również zaproponowana nowatorska metoda oceny rozkładu siły pod ochraniaczem, podczas badań na stanowisku, wykorzystująca cienkościenne czujniki ciśnienia. Procedura badań ochraniaczy przeciwuderzeniowych przewiduje także, możliwość porównania wytypowanych wskaźników z przyjętymi w literaturze biomechanicznej wybranymi kryteriami dla określania poziomu ludzkiej tolerancji na uszkodzenie danego obszaru ciała.
As a result of research work, the fibrous material featuring 3D-structure has been developed and dedicated for impact-resistant layers of protectors applied in clothing and protective equipment for individuals practising traumatic sports. The material was gained by innovative applying eco-friendly coconut fibres, reach of lignin and binding means with co-polymer of ethylene and vinyl acetate with porogenous agent. The developed material has been submitted in 2005 under the name of IMPACTEX to the Patent Office as the invention project no. P-374169. Its efficiency on attenuating the energy of hitting was confirmed by the results of tests executed on a workstation designed for assaying the sports protectors' capability to suppress impacts. The original design of the workstation allows for such an assay with two test methods applied simultaneously. An innovative method of assaying the force distribution under the protector was also suggested, while testing on the workstation with thin-walled pressure sensors used. The testing procedure for impact-resistant protectors includes also the possibility of comparison selected indices to the selected criteria accepted by biomechanical bibliography to determine level of human toleration for injury of given area of body.

Źródło:

Techniczne Wyroby Włókiennicze; 2008, R. 16, nr 3/4, 3/4; 78-86
1230-7491

Pojawia się w:

Techniczne Wyroby Włókiennicze

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 5.

Tytuł:

Comparative assessment of heat insulation properties of thermal resistant paints with use of infrared camera

Autorzy:

Kruczek, T.
Szczygieł, I.
Kruczek, G.
Kowalczyk, P.

Powiązania:

https://bibliotekanauki.pl/articles/114646.pdf

Data publikacji:

2017

Wydawca:

Stowarzyszenie Inżynierów i Techników Mechaników Polskich

Tematy:

thermovision infrared measurements
thermal resistant paint

Opis:

To reduce heat losses from buildings various methods are used. One of them is applying so called “thermal resistant paints”. These paints can be put in principle on the inner but also on outer surfaces of building external walls. The aforementioned paints are put on a surface in the similar way as other paints in building construction technology and form a thin insulation layer. The acting of this paints consists in causing a noticeable temperature drop within this layer and simultaneously on the wall surface. This work presents the experimental rig, measurement procedures and selected measurement results.

Źródło:

Measurement Automation Monitoring; 2017, 63, 3; 98-101
2450-2855

Pojawia się w:

Measurement Automation Monitoring

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 6.

Tytuł:

Antibiotic resistance of bacteria and incidence of carbapenamase-coding genes blaPER and blaGES in isolates from wastewater treatment plants

Autorzy:

Jendrzejewska, Natalia

Powiązania:

https://bibliotekanauki.pl/articles/1178215.pdf

Data publikacji:

2018

Wydawca:

Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN

Tematy:

antibiotics-resistant bacteria
genes
pollution
wastewater

Opis:

The increase in number of antibiotic resistant bacteria poses a serious environmental and health problem. The development of microbial resistance is intensified by the widespread use of antibiotics in medicine, veterinary, farming and aquaculture. The wastewater treatment plants receiving the wastewater from hospitals, slaughterhouses, farms, pharmaceutical industry and houses can be potential places of spreading of antibiotic resistant genes. The molecular mechanisms of the bacterial resistance, including the horizontal transfer of antibiotic resistant genes and the presence of mobile genetic elements can be responsible for the increase in antibiotic resistance during wastewater treatment. The aim of this study was to analyze the phenomenon of bacterial resistance to selected β-lactam antibiotics (ESBL) by detecting the genes that determine this resistance. The PCR method was used to analyze the occurrence of two genes: blaPER and blaGES in wastewater samples. It was revealed that the resistant/total bacteria ratio was significantly higher in the effluent compared with the influent wastewater. Genes blaPER and blaGES were isolated from several strains predominating in both aeration tank (5% and 20% respectively) and effluent wastewater (15% and 12% respectively).

Źródło:

World Scientific News; 2018, 93; 30-39
2392-2192

Pojawia się w:

World Scientific News

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 7.

Tytuł:

Analyses of the genes involved in disease development to construct disease-resistant plants by genetic engineering

Autorzy:

Tsuyumu, S.
Hirata, H.

Powiązania:

https://bibliotekanauki.pl/articles/385202.pdf

Data publikacji:

2009

Wydawca:

Sieć Badawcza Łukasiewicz - Przemysłowy Instytut Automatyki i Pomiarów

Tematy:

genes
analyses
disease-resistant
genetic engineering

Opis:

Many genes responsible for the disease development were identified from transposon-tagging, micro-array, and proteomics analyses. Here, we introduce especially the genes required for the initiation of pathogenic life cycle, the suppression of otherwise induction of resistance responses, massive production of virulence factors in plant pathogenic bacteria and an unique plant gene responsible for the development of canker symptom. From these findings we came to raise some new strategies to construct disease-resistant plants by genetic engineering.

Źródło:

Journal of Automation Mobile Robotics and Intelligent Systems; 2009, 3, 4; 84-86
1897-8649
2080-2145

Pojawia się w:

Journal of Automation Mobile Robotics and Intelligent Systems

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 8.

Tytuł:

Acinetobacter Baumannii Nosocomial Infections

Autorzy:

Sieniawski, Karol
Kaczka, Krzysztof
Rucińska, Monika
Gagis, Ludmiła
Pomorski, Lech

Powiązania:

https://bibliotekanauki.pl/articles/1396395.pdf

Data publikacji:

2013-09-01

Wydawca:

Index Copernicus International

Tematy:

Acinetobacter baumannii
nosocomial infections
multidrug-resistant

Opis:

Nosocomial infections caused by strains Acinetobacter baumannii strands are a growing clinical problem. The occurrence of multidrug-resistant strands is observed and that limits the ways of therapy considerably. The aim of the study was to determine the rate of infection and susceptibility spectrum of the species Acinetobacter baumannii isolated from patients treated at Maria Skłodowska-Curie Memorial Hospital in Zgierz with particular emphasis on surgical wards. Materials and methods. The material consisted of Acinetobacter baumannii isolates were obtained from samples of materials from patients treated at Maria Skłodowska-Curie Memorial Hospital in Zgierz from January to December 2011. Isolated bacterial strains were cultured at microbiological substrates. Isolates were identified to species using the VITEK 2 GN card (bioMérieux) and Vitek 2 automated system (bioMérieux). Susceptibility towards antibiotics of particular strains was determined by the means of AST NO 93 card. In the case of resistance towards carbapenem, the MIC was marked by E-test with Mueller Hinton substrate. The occurrence of MBL was verified by the means of disc system with Mueller Hinton substrate. Results. We have shown that total number of Acinetobacter baumannii infections at hospital was 140 (10,31% of total results of cultures). Percentage of Acinetobacter baumannii infections at wards: Intensive Care Unit 48%, Surgical Departments 20%, Internal Diseases Department 16%, Neurology 13%, other wards - 3%. The susceptibility percentage of Acinetobacter Baumannii against antibiotics: colistin 90%, imipenem 64%, meropenem 43%, ampicillin-sulbactam 28%, amikacin 27%, gentamicin 24%, cefepime 9%, ceftazidime 7%, ciprofloxacin 7% Conclusions. Acinetobacter baumannii infections are a significant proportion of nosocomial infections. Most relate to surgical wards and ICUs. Acinetobacter baumannii is resistant against most antibiotics. The highest percentage of sensitivity demonstrated for colistin and carbapenems

Źródło:

Polish Journal of Surgery; 2013, 85, 9; 483-490
0032-373X
2299-2847

Pojawia się w:

Polish Journal of Surgery

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 9.

Tytuł:

Past, Present & Future of Thermally Stable Explosives

Autorzy:

Agrawal, J. P.

Powiązania:

https://bibliotekanauki.pl/articles/358166.pdf

Data publikacji:

2012

Wydawca:

Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego

Tematy:

explosives
thermally stable explosives
heat-resistant explosives

Opis:

Explosives with improved high temperature properties are usually referred to as 'thermally stable explosives' or heat-resistant explosives. They are safer, more reliable and more stable at elevated temperatures and find applications in modern Ordnance, Space and Nuclear applications. This paper discusses general approaches for the synthesis of thermally stable explosives, their properties and specific applications. This paper also gives a comparative account of the properties of some of the most thermally stable explosives reported so far. Based on their ease of synthesis, properties (mainly stability at elevated temperatures and insensitivity to impact, friction and percussion) and cost, TATB is considered as a benchmark, thermally stable explosive which is discussed in detail. Furthermore, this review also describes the synthesis and properties of BTDAONAB which does not melt below 550 °C and is considered a better thermally stable explosive than TATB. Finally, a new line of research in this field in the years to come is also highlighted.

Źródło:

Central European Journal of Energetic Materials; 2012, 9, 3; 273-290
1733-7178

Pojawia się w:

Central European Journal of Energetic Materials

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 10.

Tytuł:

Degradation of the gas turbine blade coating and its influence on the microstructure state of the superalloy

Autorzy:

Błachnio, J.
Kułaszka, A.
Zasada, D.

Powiązania:

https://bibliotekanauki.pl/articles/244112.pdf

Data publikacji:

2015

Wydawca:

Instytut Techniczny Wojsk Lotniczych

Tematy:

turbine
blade
heat-resistant coating
technical condition

Opis:

The technical condition of the blades has a critical influence on the reliability and life span of a gas turbine and an engine into which it is built in. The main causes of blade damage are overheating, creeping, thermal fatigue, high temperature corrosion, etc. It is often caused by adverse operational conditions or manufacturing defect, e.g. using insufficiently durable types of heat-resistant protective coatings or applied in an improper manner on the blade material. Reaction of coatings and blade material to mechanical and thermal loads depends mainly on the operating temperature of the turbine. Selection of a protective coating and material to manufacture a blade with an assumed strength must take into account its mechanical and thermal properties at maximum aerofoil temperature. The article presents characteristic forms of operational damages to the gas turbine blades of a turbojet aero engine. Distinguished were operational factors and their influence on the technical condition of coatings during the engine operation period. An influence of excess exhaust gas temperature on the condition of the heat-resistant blade layer was shown. Shown were also results of morphology tests of coating degradation types. Results of micro-structure tests of the blade superalloy after damage to the heat-resistant coating were also presented.

Źródło:

Journal of KONES; 2015, 22, 2; 17-24
1231-4005
2354-0133

Pojawia się w:

Journal of KONES

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 11.

Tytuł:

A Comparism of the Response of Some Pearl Millest (Pennisetum glaucum (L.) R. BR) Hybrids and Their Parents to Downy Mildew (Sclerospora graminicola) Infestation in Bakura and Zaria (North-western Nigeria)

Autorzy:

Maryam, Ati H.
Angarawai, I. I.

Powiązania:

https://bibliotekanauki.pl/articles/1178552.pdf

Data publikacji:

2017

Wydawca:

Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN

Tematy:

downy mildew
hybrids
obligate biotrophs
resistant
tolerance

Opis:

Downy mildew (Sclerospora graminicola (Sacc) Schroet.) of pearl millet [Pennisetum glaucum (L.) R.Br.] is a devastating disease that has greatly led to grain yield loss in Nigeria. A field experiment was carried out in 2010 at Bakura (Zamfara State) and Zaria (Kaduna State) in North West Nigeria. The objective of this paper was to evaluate downy mildew resistance in some pearl millet using Complete Randomized Block Design. Four resistant male varieties (PEO5532, SOSATC88, P1449 and DMR15) and four susceptible female varieties (BDP1, MOP1, LCIC9702 and PEO5984 were used in this study. The resistant varieties were crossed with the susceptible varieties using North Carolina design 11 for the mating to form sixteen (F1) hybrids. The F1 hybrids were further evaluated along with their parents for downy mildew resistance, grain yield and other agronomic traits (such as: Plant height, panicle height, number of tillers per plant, panicle diameter and number panicles per plot). The resistant male parents were found to be susceptible while none of the hybrids was resistant to downy mildew. However, the degree of incidence and severity of downy mildew disease defer in the two locations. The hybrids exhibited tolerance to downy mildew disease and their yields were higher than their parents. The analysis of variance (one tale ANOVA or which one?) showed highly significant difference among parents and hybrids for all agronomic characters except disease severity and number of tillers per plant. Location × genotype interaction effects were only significant for grain yield and number of panicles per plot.

Źródło:

World Scientific News; 2017, 70, 2; 252-264
2392-2192

Pojawia się w:

World Scientific News

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 12.

Tytuł:

Occurrence of high-level aminoglycoside resistance (HLAR) among Enterococcus species strains

Autorzy:

Sieńko, A.
Wieczorek, P.
Wieczorek, A.
Sacha, P.
Majewski, P.
Ojdana, D.
Michalska, A.
Tryniszewska, E.

Powiązania:

https://bibliotekanauki.pl/articles/1916469.pdf

Data publikacji:

2014

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

enterococcus
aminoglycoside resistance
vancomycin-resistant
enterococcus (VRE)

Opis:

Purpose: Today, Enterococcus species are one of the most frequent etiological agents in nosocomial infections. The aim of this study was to determine the susceptibility to antibiotics and the prevalence of high-level aminoglycoside resistance (HLAR) among Enterococcus strains. Materials and methods: The susceptibility of 85 isolates of Enterococcus (47 E. faecalis and 38 E. faecium) was determined using the disk diffusion method. The results were interpreted according to European Committee on Antimicrobial Suscepti-bility Testing (EUCAST) guidelines. PASW Statistics 17.0 was used for statistical analysis. Results: E. faecalis strains showed the highest susceptibility to ampicillin, tigecycline, vanco-mycin, imipenem, and linezolid and E. faecium to linezolid, tigecycline, and quinupristin/dalfopristin. Among all tested strains, high-level gentamicin resistance (HLGR) was found in 4% of E. faecalis and 8% of E. faecium strains, high-level strepto-mycin resistance (HLSR) in 45% and 42%, and HLAR in 50% and 32% of strains, respectively. HLGR was detected only in vancomycin-resistant Enterococcus (VRE)− strains (12%), while HLSR in 76.9% of VRE+ and 24% of VRE− strains, and HLAR in 23.1% of VRE+ and 64% of VRE− strains. The tested strains were also divided into two groups: HLSR+ and HLAR+. In both groups, statistically significant susceptibility differences (p<0.05) were found for ampicillin, imipenem and trimethoprim/sulfamethoxazole. The most frequent antibiotic resistance profile among E. faecalis strains was SR (resistance phenotype to strepto-mycin), and among E. faecium, AMPR, IMPR, CNR, SR, SXTR (ampicillin, imipenem, gentamicin, streptomycin, trimethoprim/sulfamethoxazole). Conclusions: This study showed the slowly increasing prevalence of HLAR and resistance to newer antibiotics (linezolid and tigecycline) among Enterococcus strains. It is necessary to search for new directions in the treatment of enterococcal infections.

Źródło:

Progress in Health Sciences; 2014, 4, 1; 179-187
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 13.

Tytuł:

Apalutamide in the treatment of a patient with non-metastatic castration-resistant prostate cancer

Autorzy:

Dziura, Robert

Powiązania:

https://bibliotekanauki.pl/articles/22676763.pdf

Data publikacji:

2023-03-31

Wydawca:

Medical Education

Tematy:

prostate cancer
castration-resistant
androgen receptor inhibitor

Opis:

The treatment of patients with prostate cancer, who do not qualify for the radical therapy is based on the use of surgical or pharmacological castration methods. The effectiveness of the so-called androgen deprivation tends to decrease over time. Even in the absence of distant metastases on imaging studies, the resistance for the hormonal castration may be developed. At this moment, the use of new generation androgen receptor inhibitors may reduce the risk of metastases or death. The paper presents a case report of a patient with prostate cancer without distant metastases who started therapy with apalutamide at the moment of developing re-sistance to the pharmacological castration.

Źródło:

OncoReview; 2023, 13, 1; 20-23
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 14.

Tytuł:

Apalutamide as a new option for postponing metastatic disease in hormone -resistant patients with biochemical recurrence in prostate cancer

Autorzy:

Dąbek, Bartosz

Powiązania:

https://bibliotekanauki.pl/articles/22676825.pdf

Data publikacji:

2023-04-04

Wydawca:

Medical Education

Tematy:

non-metastatic castration-resistant prostate cancer
apalutamide

Opis:

Treatment of non-metastatic castration-resistant prostate cancer is a radically new option for cancer patients. Novel anti-hormonal therapy not only improves metastasis free survival but overall survival times and positively impacts quality of life. This case shows how apalutamide lowered tPSA level and postponed metastatic disease.

Źródło:

OncoReview; 2023, 13, 1; 24-26
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 15.

Tytuł:

Pollution in Shatt Al-Arab River near Hospital Wastewater Disposal – Detection of Pharmaceutical Compounds, Isolation and Identification of Drug-Resistant Bacteria

Autorzy:

Alsaad, Noor Kadhim
Almansoory, Asia Fadhile
Al-Baldawi, Israa Abdulwahab

Powiązania:

https://bibliotekanauki.pl/articles/2202283.pdf

Data publikacji:

2022

Wydawca:

Polskie Towarzystwo Inżynierii Ekologicznej

Tematy:

resistant bacteria
well diffusion
river
pharmaceutical
micropollutants

Opis:

Pharmaceutical compounds have been introduced into the aquatic ecosystems in multiple ways and sources, which negatively affects the health of the environment and humans. The river near the hospital sewage disposal is host environment for drug-resistant bacteria (DRB). In this context, the aim of the research was to detect the presence of pharmaceuticals in hospital wastewater, after treatment, at river point followed by isolation of bacteria and test for resistant pharmaceutical compound. Fifteen species of bacteria isolated by angiogenic methods were identified and tested using the well diffusion test to determine the resistance of selected bacteria to ibuprofen by survival assessment. This study showed that the ibuprofen detected by GC-mass was available in all selected points at a concentration of 3 to 120 mg/L. Lecuco. mesen.cremris and Koc.rosea have a high ability to break down the ibuprofen compound. Thus, the bacteria isolated from hospital wastewater can biologically degrade ibuprofen.

Źródło:

Journal of Ecological Engineering; 2022, 23, 12; 29--36
2299-8993

Pojawia się w:

Journal of Ecological Engineering

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 16.

Tytuł:

Comparative analysis of welded and adhesive joints strength made of acid-resistant stainless steel sheets

Autorzy:

Rudawska, A.
Pawlak, P.
Miturska, I.
Stančeková, D.
Chyra, M.

Powiązania:

https://bibliotekanauki.pl/articles/102070.pdf

Data publikacji:

2017

Wydawca:

Stowarzyszenie Inżynierów i Techników Mechaników Polskich

Tematy:

adhesive joints
welded joints
strength
acid resistant steel

Opis:

The article presents the selected results of strength tests on the effectiveness of bonding high-alloy steel 1.4310. Sheet steel is one of the materials that are difficult to activate energy. Effective joining of it is difficult, requires selection of the appropriate bonding technology. The paper focuses on the comparative tests of shear strength of one-single lap welded and bonded joints. The welding process was performed on 3 groups of samples TIG welding and argon, where the variable value of the welding process was current: 60A, 70A, 80A. The adhesion process was performed in 6 groups of samples which differed in the method of surface preparation and the type of the adhesive. Adhesive joints were made by using adhesive of epoxy resin and a hardener: Epidian 61/TFF at a mass ratio of 100:22 and Epidian 61/IDA at a mass ratio of 100:40. As a way of surface preparation applied 3 different, but simplified and environmentally friendly methods of surface preparation: degreasing with using cleaner Loctite 7061, abrasive machining with P320 and degreasing and grinding with abrasive T800 and degreasing were used. Make joints and curing the adhesive joints were carried out at ambient temperature. Analyzed the joints were tested destructive – which set out the shear strength, in accordance with DIN EN 1465 on the testing machine Zwick / Roell Z150. Based on the results of the research it was found that better results were obtained for the maximum welded joints, but this result was similar to the maximum value of the strength of the adhesive bond.

Źródło:

Advances in Science and Technology. Research Journal; 2017, 11, 4; 97-102
2299-8624

Pojawia się w:

Advances in Science and Technology. Research Journal

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 17.

Tytuł:

Cardiovascular complications during the treatment of castration-resistant prostate cancer with the use of modern antiandrogens: abiraterone acetate and enzalutamide

Autorzy:

Grabysa, Radosław
Chmielewska, Agnieszka

Powiązania:

https://bibliotekanauki.pl/articles/2047222.pdf

Data publikacji:

2021-09-13

Wydawca:

Medical Education

Tematy:

abiraterone acetate
enzalutamide
castration resistant prostate cancer
cardiovascular

Opis:

Modern antiandrogens: abiraterone acetate (inhibitor of CYP17 cytochrome) and enzalutamide (irreversible inhibitor of androgen receptor) are the drugs that are increasingly often administered in treatment of castration-resistant prostate cancer. Despite their clinical efficacy, especially in terms of prolonged survival and improved quality of life of patients, they pose of problem for a practicing oncologist such as possible cardiovascular complications (particularly arterial hypertension), which may lead to the cessation of this form of therapy. This article provides a brief overview of the mechanisms responsible for the above complications, including practical recommendations in the event such complications arise. A simple scheme of action for control of cardiovascular risk factors has been presented, which can improve the prognosis in this population of patients.

Źródło:

OncoReview; 2021, 11, 3; 61-67
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 18.

Tytuł:

Multiaxial force platform with disturbance compensation for machine tools

Autorzy:

Palalic, Marijana
Möhring, Hans-Christian
Maier, Walther
de Mendoza, Adrian Gonzalez
Riemeier, Friedrich

Powiązania:

https://bibliotekanauki.pl/articles/99882.pdf

Data publikacji:

2020

Wydawca:

Wrocławska Rada Federacji Stowarzyszeń Naukowo-Technicznych

Tematy:

force determination platform
disturbance-resistant
FEA
multibody system

Opis:

As part of a cooperation project between the Institute for Machine Tools, Stuttgart, Germany, and EMO Systems/Nuton GmbH, Berlin, Germany, a prototype of a multiaxial force platform with disturbance compensation for the measurement of the cutting forces in machine tools was developed. Commercially available products based on piezoelectric technology are subject to a degree of measurement uncertainty and therefore characterized by various disturbances. Interpreting measurement data of the commercially available products is complex, time-consuming and prone to errors. This paper describes the mechanical design and the simulation of the multiaxial force measuring system with the finite element method (FEM) as well as the conceptual development of a reduced model for a multibody simulation with the purpose of implementing a compensation algorithm. The measurement uncertainty was reduced by using appropriate hardware and software for the compensation of the various disturbances so that the application of the force platform would also be possible in the industrial application for the process diagnosis, the control and the regulation in machine tools. Systems based on strain gauge technology have some advantages in the field of zero-point stability and also provide a less expensive solution. For the disturbance compensation, an additional force and torque sensor system with eight channels was used for the detection of the platform displacement and inclination. With the help of appropriate algorithms for the disturbance compensation and their integration in the evaluation software, the disturbances could be reduced to a minimum.

Źródło:

Journal of Machine Engineering; 2020, 20, 3; 5-16
1895-7595
2391-8071

Pojawia się w:

Journal of Machine Engineering

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 19.

Tytuł:

Ochraniacze przeciwuderzeniowe w sporcie - moda i konieczność
Impact-resistant protectors at sports - fashion and necessity

Autorzy:

Maklewska, E.

Powiązania:

https://bibliotekanauki.pl/articles/237926.pdf

Data publikacji:

2008

Wydawca:

Instytut Technologii Bezpieczeństwa Moratex

Tematy:

ochraniacze przeciwuderzeniowe
sport
urazy
impact-resistant protectors
injuries

Źródło:

Techniczne Wyroby Włókiennicze; 2008, R. 16, nr 1/2, 1/2; 8-14
1230-7491

Pojawia się w:

Techniczne Wyroby Włókiennicze

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 20.

Tytuł:

Multi Drug Resistant Tuberculosis

Autorzy:

Zacharia, Balaji
Roy, Antony

Powiązania:

https://bibliotekanauki.pl/articles/454987.pdf

Data publikacji:

2019

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

BACTEC
MDRTB
multi drug resistant tuberculosis Mycobacterium
tuberculosis

Opis:

Introduction. Tuberculosis is one of the oldest infections known to mankind. Of all infectious diseases, tuberculosis causes the most fatalities of any infection. The incidence of tuberculosis on the rise due to the increased prevalence of HIV infection. The incidence of drug resistance strains of mycobacterium is also on the rise. When the mycobacterium is resistant to both INH and rifampicin it is called multi drug resistant tuberculosis. There is a primary and an acquired type of drug resistance. Multidrug resistant tuberculosis is a not only a problem for the patient but also for society at large. The treatment of multidrug resistant tuberculosis requires an entirely different approach. Aim. In this review, we are going to describe the etiopathogenesis, diagnosis, investigations and treatment of multi drug resistant tuberculosis. Material and methods. Analysis of the current literature. Results. Genetic factors, previous treatment, and other factors predisposes the onset of drug resistance. By early detection and prevention of spread of drug resistant strains we can prevent the spread of resistant strains. Conclusion. Drug resistance in tuberculosis is a very complex and dangerous problem. We have to prevent the development and spread of MDRTB. Good quality drugs should be used and made available to all sections of the population. Enhancing the National tuberculosis programs is the best way to attain an effective way to control this menace.

Źródło:

European Journal of Clinical and Experimental Medicine; 2019, 3; 262-269
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 21.

Tytuł:

The Potential of Mercury-Resistant Bacteria Isolated from Small-Scale Gold Mine Tailings for Accumulation of Mercury

Autorzy:

Chasanah, U.
Nuraini, Y.
Handayanto, E.

Powiązania:

https://bibliotekanauki.pl/articles/124273.pdf

Data publikacji:

2018

Wydawca:

Polskie Towarzystwo Inżynierii Ekologicznej

Tematy:

mercury-resistant bacteria
small-scale gold mine tailing

Opis:

In certain small-gold mining activities in West Lombok, Indonesia, the tailings containing mercury are discharged to agricultural lands, reducing their productivity. One of the efforts to restore the land is by bioremediation of mercury, using mercury-resistant microbes. This study was aimed to isolate the mercury-resistant bacteria from small-scale gold mine tailings containing mercury, and to test their capability in accumulating mercury. Bacterial isolation and identification were conducted from nutrient broth supplemented with 5 ppm HgCl₂. The isolated bacteria were tested for mercury accumulation in the nutrient broth containing 10, 20 and 30 ppm Hg for 24 hours, and in small-scale gold mine tailing containing 41.37 ppm Hg for 2 weeks. The results showed that there were four pure isolates of mercury-resistant bacteria which were identified as Brevundimonas vesicularis, Nitrococcus mobilis, Fusobacterium aquatile and Fusobacterium necrogenes. The highest Hg accumulation from nutrient broth liquid media containing 10, 20 and 30 ppm Hg was observed for Brevundimonas vesicularis. The mercury accumulation efficiency of the four bacteria applied to small-scale gold mine tailing containing mercury was in the order of Fusobacterium aquatile (76.1%) > Brevundimonas vesicularis (75.6%) > Fusobacterium necrogenes (74.4%) > Nitrococcus mobilis (74.2%). On the basis of the Hg accumulation efficiency of more than 75%, Fusobacterium aquatile and Brevundimonas vesicularis are prospective for bioremediation of mercury-contaminated soils.

Źródło:

Journal of Ecological Engineering; 2018, 19, 2; 236-245
2299-8993

Pojawia się w:

Journal of Ecological Engineering

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 22.

Tytuł:

Analysis of Acinetobacter baumannii resistance patterns in patients with chronic obstructive pulmonary disease (COPD) in terms of choice of effective empiric antibiotic therapy

Autorzy:

Grochowalska, Aneta
Kozioł-Montewka, Maria
Sobieszczańska, Anna

Powiązania:

https://bibliotekanauki.pl/articles/989765.pdf

Data publikacji:

2017

Wydawca:

Instytut Medycyny Wsi

Tematy:

copd
antibiotics
acinetobacter baumannii
multidrug-resistant strains
co-infection

Opis:

Introduction. Multi-resistant Acinetobacter baumannii isolated from patients has become one of the most hazardous pathogens in health care settings. The aim of the study was to analyze pneumonia caused by Acinetobacter baumannii in patients hospitalized because of exacerbation of chronic obstructive pulmonary diseases (COPD), who were admitted to the Pulmonology Ward of the Masovian Specialistic Hospital in Radom (MSS). The incidence and drug sensitivity of these non-fermenting rods were evaluated, and compliance with antimicrobial procedure with the algorithm of the guidelines in applicable recommendations, was estimated. This should result in determining the local patterns of resistance and verifying therapeutic procedures in accordance with the assumptions of hospital antibiotic policy. In addition, the study examined the effectiveness of empiric and targeted therapy according to the clinical condition of the patient, and the eradication of A. baumannii, in comparison with the aggravating factors of the patient. Materials and Method. The retrospective study included 90 patients with exacerbation of COPD whose etiological factor of infection was A. baumannii, hospitalized in the Department of Pulmonology (MSS) in 2012–2016. Results. Studies were conducted on 90 patients with COPD exacerbation from which A. baumannii was isolated. Co-infections with other bacterial species among 41 patients were additionally noted. The majority of A. baumannii strains showed a high resistance (90%) to fluoroquinolones, ceftazidime, piperacillin/tazobactam. For strains causing a co-infection, drug resistance was successively 44–56%, 44%, 44%. All of patients received empirical therapy. The most commonly used drug was amoxicillin with a clavulanic acid, often combined with fluoroquinolone. This type of therapy was effective among 10% of patients. The mortality in this group was determined at 29%. Among 79% of patients with COPD, a targeted therapy was performed which proved to be effective in 58% of treated cases by susceptibility testing. The highest efficacy was observer after the use of colistin and carbapenems. Conclusion. In the performed study, the infections caused by multi-resistant Acinetobacter baumannii, were observed in COPD, which should be taken into consideration in choosing empirical antibiotic therapy. Simultaneously, the local resistance patterns of multi-drug-resistant (MDR) Gram-negative strains co-infecting COPD should be considered in empirical treatment. Moreover, both additional clinical complication and co-infections contribute to a more severe course of diseases. In this study, the mortality percent exceeded 29%.

Źródło:

Annals of Agricultural and Environmental Medicine; 2017, 24, 2
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 23.

Tytuł:

Image encryption based on Chebyshev chaotic map and S8 S-boxes

Autorzy:

Hussain, Iqtadar
Anees, Amir
Alkhaldi, Ali Hussain
Aslam, Muhammad
Siddiqui, Nasir
Ahmed, Rehan

Powiązania:

https://bibliotekanauki.pl/articles/173918.pdf

Data publikacji:

2019

Wydawca:

Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej

Tematy:

image encryption
chaos
noise-resistant
statistical analysis
key sensitivity

Opis:

The encryption of image data is artful as compare to others due to some special characteristics such as entropy, contrast, the correlation between the pixels, intensity, and homogeneity. During encryption process, it is conventionally not easy to manage these characteristics with non-chaotic cryptosystems. Therefore for the sake of strong encryption algorithms, in last decades many cryptographers have presented invulnerable schemes for image encryption based on the chaotic maps. This manuscript aims to propose a strong encryption scheme based on a symmetric group of permutation advanced encryption standard (AES) substitution boxes and modified Chebyshev map. Principally, the secret key depends upon the parameters of Chebyshev map to create confusion in the main image and is encrypted by the scheme made from the S8 AES S-boxes and chaotic map. By this procedure, one can obtain an encrypted image that is entirely twisted. The results of analyses showed that the presented image encryption is strong and invulnerable.

Źródło:

Optica Applicata; 2019, 49, 2; 317-330
0078-5466
1899-7015

Pojawia się w:

Optica Applicata

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 24.

Tytuł:

Apalutamide in the treatment of non-metastatic castration-resistant prostate cancer in an elderly patient with multiple comorbidities

Autorzy:

Liśkiewicz, Katarzyna

Powiązania:

https://bibliotekanauki.pl/articles/22676727.pdf

Data publikacji:

2023-03-30

Wydawca:

Medical Education

Tematy:

non-metastatic castration-resistant prostatic cancer
androgen receptor
apalutamide

Opis:

Prostate cancer has been the most common malignant tumor in men in Poland since 2016 and is the second cause of death in this group of patients. The basic method of treatment in patients with advanced prostate cancer is androgen deprivation therapy, however, over time, the tumor evolves into a castration-resistant form, which poses a significant threat to the patient's life. This article presents a case of an elderly patient with internal diseases, who in the castration-resistant stage, was treated with a new generation androgen receptor blocker – apalutamide – in the first line of systemic treatment.

Źródło:

OncoReview; 2023, 13, 1; 9-12
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 25.

Tytuł:

Effects of an enzyme agent containing mutanase and dextranase for treatment of biofilms in bacteria- and yeast-infected canine otitis externa

Autorzy:

Fujimura, M.

Powiązania:

https://bibliotekanauki.pl/articles/16539344.pdf

Data publikacji:

2022

Wydawca:

Polska Akademia Nauk. Czasopisma i Monografie PAN

Tematy:

biofilm
canine otitis externa
enzyme agents
drug-resistant bacteria

Opis:

The purpose of this study was to evaluate in detail both the in vivo and in vitro efficacy of the enzyme agents, ZYMOX® Plus Otic (ZYMOX-P), in the treatment of canine otitis externa (OE). Eight dogs with a diagnosis of non-seasonal severe chronic OE were recruited for the study. ZYMOX-P was administered for 2-4 weeks. The Otitis Index Score (OTIS3) and bacteria or yeast colony growth were measured. Also, minimum biofilm (BF) formation inhibition concentration (MBIC) and BF bactericidal concentration (BBC) were measured in vitro. OTIS3 showed a statistically significant reduction after treatment (88.2%, p<0.001; pre-treatment = 11.0 ± 0.9; post-treatment = 1.3 ± 0.4, mean ± SEM). The individual OTIS scores, erythema, edema, erosions/ ulcerations, exudate and pruritus showed significant reduction (85.7%, 95.7%, 83.3%, 80.0%, and 89.3%, respectively). Microscopic examination revealed the presence of BF exopolysaccharide in all 8 ear samples when stained with alcian blue. Seven of the 8 dogs (87.5%) showed a reduction in colony growth. ZYMOX-P was effective at 34-fold and 16-fold dilutions on MBIC and BBC, respectively. These findings indicate that ZYMOX-P has efficacy against BF-related infection and is beneficial when used for the management of canine OE.

Źródło:

Polish Journal of Veterinary Sciences; 2022, 25, 3; 383-389
1505-1773

Pojawia się w:

Polish Journal of Veterinary Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 26.

Tytuł:

The inhibition of methicillin-resistant Staphylococcus aureus by essential oils isolated from leaves and fruits of Schinus areira depending on their chemical compositions

Autorzy:

Celaya, Liliana
Alabrudzińska, Marta
Molina, Ana
Viturro, Carmen
Moreno, Silvia

Powiązania:

https://bibliotekanauki.pl/articles/1039327.pdf

Data publikacji:

2014

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

Schinus areira
essential oils
antibacterial
Methicillin-resistant Staphylococcus aureus

Opis:

Schinus areira L. is a native plant from South America used for centuries in traditional medicine. Here, we investigate the antimicrobial activity of four essential oils extracted from leaves and fruits of S. areira exhibiting different chemical profiles. The antibacterial activity against the human pathogenic bacteria Staphylococcus aureus susceptible as well as methicillin resistant strain was assessed by the broth microdilution assay. The results showed that the limonene-rich oil extracted from the leaves and fruits have potent antibacterial effect on S. aureus ATCC 25923, while the α-phellandrene-rich fruit oil having a lower content of limonene showed the lowest antibacterial efficacy. In this work, for the first time, we demonstrated the bactericidal activity of essential oils isolated from fruits and leaves of S. areira against susceptible and methicillin resistant S. aureus strains. All results point out the potential use of the S. areira oils as antimicrobial agents to be used, at least against Staphylococcal infections.

Źródło:

Acta Biochimica Polonica; 2014, 61, 1; 41-46
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 27.

Tytuł:

Ocena zmian strukturalnych stali żaroodpornej x10CrAl24 eksploatowanej w wysokiej temperaturze pieca energetycznego
Evaluation of structural changes of steel heat-resistant operated x10CrAl24 high temperature furnace energy

Autorzy:

Budzynowski, T.
Nowak, P.
Żurowski, W.

Powiązania:

https://bibliotekanauki.pl/articles/254305.pdf

Data publikacji:

2015

Wydawca:

Instytut Naukowo-Wydawniczy TTS

Tematy:

stal żaroodporna
piec energetyczny
heat resistant steel
energy stove

Opis:

W pracy przedstawiono wyniki badań zmian mikrostruktury stali żaroodpornej chromowo-krzemowej z dodatkiem aluminium wywołanych długotrwałym oddziaływaniem temperatur w zakresie 500 ÷ 1100 °C, w czasie 140 godzin, w piecach opalanych węglem w strefach (II ciąg - 500°C, kiosk - 700°C, na grodzi - 850°C, nad sklepieniem - 1000°C) w przedsiębiorstwie energetycznym „Radpec” w Radomiu. Badania przeprowadzono podczas normalnej eksploatacji, próbki umieszczono w różnych strefach kotła energetycznego dwuciągowego opalanego materiałem węglowym.
The paper presents the results of changes in the microstructure of steel heat-resistant chrome-silicon aluminum are caused by long-term effects of temperatures in the range of 500 ÷ 1100 ° C for 140 hours, furnaces fired power zones (the second string - 500 ° C, kiosk - 700 ° C, on the bulkhead - 850 ° C above the firmament - 1000 ° C) energy company "Radpec" in Radom. The study was conducted in normal operation, the samples were placed in different zones of the steam boiler fired with a drawing of two carbonaceous material.

Źródło:

TTS Technika Transportu Szynowego; 2015, 12; 214-218, CD
1232-3829
2543-5728

Pojawia się w:

TTS Technika Transportu Szynowego

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 28.

Tytuł:

Composition of norfloxacin-resistant bacteria and isolation of norfloxacin-degrading bacteria in subtropical aquaculture ponds in China

Autorzy:

Mao, Lutian
Chen, Lifen
Wang, Xirui
Xu, Zhongbao
Ouyang, Hui
Huang, Biyou
Zhou, Libin

Powiązania:

https://bibliotekanauki.pl/articles/4790189.pdf

Data publikacji:

2022

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

high-throughput sequencing
norfloxacin
antibiotic resistant bacterium
pond culture

Opis:

To analyze the composition of norfloxacin-resistant bacteria and norfloxacin-degrading bacteria in pond water and sediment in subtropical China, the composition of antibiotic resistant bacteria in pond water and sediment enriched with norfloxacin-containing medium was analyzed by high-throughput sequencing. Sediment and water samples were collected from 3 fish ponds in subtropical China, and domesticated with norfloxacin, subsequently norfloxacin-resistant bacteria through high-throughput sequencing of 16S rDNA, and isolated norfloxacin--degrading bacteria. Our results showed that the pond sediment and water contain a variety of norfloxacin-resistant bacteria, mainly from Proteobacteria, Bacteroidetes, Actinobacteria, Firmicutes, and Chloroflexi. Moreover, we isolated two norfloxacin-degrading bacteria (NorXu-2 and NorXu-3). The norfloxacin-degrading rate by NorXu-2 and NorXu-3 in the culture mediums with 200 μg/mL was the highest, which was up to 49.71% and 35.79%, respectively. When the norfloxacin concentration was 200 μg/mL, NorXu-2 and NorXu-3 had the best norfloxacin- -degrading effect at pH of 6, and the degradation rates were 53.64% and 45.54%, respectively. Moreover, NorXu-3 exhibited a good tolerance to high NaCl concentration. These results not only provided basic data for the follow-up study of the molecular mechanism of antimicrobial microbial degradation, but also provided potential norfloxacin degrading bacteria for norfloxacin removal and bioremediation in aquaculture environment.

Źródło:

Archives of Environmental Protection; 2022, 48, 4; 95--101
2083-4772
2083-4810

Pojawia się w:

Archives of Environmental Protection

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 29.

Tytuł:

Strengthening infrastructure in management of drug resistant tuberculosis in India

Autorzy:

Shrivastava, SR.
Shrivastava, PS.
Ramasamy, J.

Powiązania:

https://bibliotekanauki.pl/articles/1914046.pdf

Data publikacji:

2014

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

tuberculosis
Revised National Tuberculosis Control Program
multi-drug resistant
India

Opis:

The emergence of resistance to first-line drugs used to treat tuberculosis (TB) has become a significant public health concern and an obstacle in implementation of effective TB control activities globally. In India, Revised National TB Control Program (RNTCP) introduced the programmatic management of drug-resistant TB (PMDT) services to address the needs of MDR-TB patients. To execute the plan with perfection, RNTCP has devised MDR suspect criteria – A, B, and C so that gradually PMDT services can be extended to the whole country. These criteria were framed to run in tandem with the strengthening of the laboratory services so that the existing certified laboratories can carry out the culture and DST services without being overburdened. Altogether, RNTCP is committed for the strengthening and capacity building of its resources to offer culture and DST services right at the time of diagnosis.

Źródło:

Progress in Health Sciences; 2014, 4, 1; 277-279
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 30.

Tytuł:

Prostate cancer in clinical practice. First experiences with apalutamide within the context of therapeutic program B.56

Autorzy:

Trzebiński, Krzysztof

Powiązania:

https://bibliotekanauki.pl/articles/22676841.pdf

Data publikacji:

2023-04-01

Wydawca:

Medical Education

Tematy:

non-metastatic castration-resistant prostate cancer
apalutamide
androgen receptor inhibitor

Opis:

The article contains a case report of patient diagnosed with castration-resistant non-metastatic prostate cancer, treated with a novel androgen receptor inhibitor – apalutamide.

Źródło:

OncoReview; 2023, 13, 1; 27-30
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 31.

Tytuł:

Basement of the alluvia influence on the channel pattern in example of selected reach of the Pilica River
Wplyw podloza aluwiow na typ rozwiniecia koryta rzecznego na przykladzie wybranego odcinka Pilicy

Autorzy:

Falkowski, T

Powiązania:

https://bibliotekanauki.pl/articles/81691.pdf

Data publikacji:

2010

Wydawca:

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie. Wydawnictwo Szkoły Głównej Gospodarstwa Wiejskiego w Warszawie

Tematy:

channel pattern
alluvial riverbed
erosion resistant deposit
Pilica River
hydrology

Opis:

The type of the channel pattern is being considered as indicative element of the fluvial environment, especially for lowland, mature rivers. Investigations carried out in the Pilica River valley (example of such river) between Inowłódz and Domaniewice (grant no 2P04E 069 29, Ministry of Science) have shown that morphological features of the valley bottom (channel zone, as well as flood terrace) depends not only on river regime, but also on channel zone geological setting. Elements of the Pilica valley geology infl uencing on fluvial processes are protrusions of alluvia basement composed of deposits resistant to erosion, crop out in the channel zone.
Typ rozwinięcia koryta rzecznego jest wskaźnikiem stanu środowiska fluwialnego i reżimu hydrologicznego szczególnie dojrzałych rzek nizinnych. Badanie prowadzone w dolinie Pilicy na odcinku między Inowłodzem a Domaniewicami (grant nr 2P04E 069 29 MNiSW) wykazały, że wpływ na morfologię i litologię zarówno strefy korytowej współczesnej Pilicy, jak i formowanej w holocenie równi zalewowej ma budowa geologiczna podłoża doliny, a szczególnie odsłaniające się w korycie kulminacje jego powierzchni zbudowane z gruntów o większej odporności na erozję. Warunkowane obecnością trudno rozmywalnych progów przepływy wezbraniowe przemodelowały powierzchnię tarasu zalewowego, a w znacznej części analizowanego odcinka zatarły także ślady holoceńskiej ewolucji rzeki. Na wielu odcinkach koryta warunkują także współcześnie jego morfologię.

Źródło:

Annals of Warsaw University of Life Sciences - SGGW. Land Reclamation; 2010, 42, 1; 93-104
0208-5771

Pojawia się w:

Annals of Warsaw University of Life Sciences - SGGW. Land Reclamation

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 32.

Tytuł:

Engineering support of the quality of surface layer of tab grooves in the discs made from heat-resistant steel

Autorzy:

Dvirna, O.

Powiązania:

https://bibliotekanauki.pl/articles/242580.pdf

Data publikacji:

2018

Wydawca:

Instytut Techniczny Wojsk Lotniczych

Tematy:

surface quality parameters
tab grooves and interlocks
heat-resistant steel

Opis:

The main idea of the work is to create scientifically grounded technological conditions for treatment of tab grooves in the discs from heat resisting steel, which stipulate formation of roughness of treated surfaces at the level of design requirements, useful compressive residual stresses and a defective surface layer, which increases reliability of operation of interlock in the absence of any defects on the working surfaces of tab grooves of various types, under conditions of maximizing efficiency of their treatment method. Dependences of roughness of the treated surface on the technological factors of the broaching process Ra = f (V, S, γ, HRC) have been proposed. As a result of experimental studies, the nature of distribution of residual stresses, depth and degree of strengthening of the surface layer, depending on the technological conditions of the tab grooves treatment, has been established. The article presents research of surface quality parameters; study all the selected parameters of the surface quality and surface layer and an algorithm to perform experimental work. The algorithm has been built on major principles of control and fixation methods, which stipulate use of non-destructive methods of control. Graphs of strengthening the surface layer of samples, depending on their processing modes and graphs of the distribution of residual stresses in the surface layer are also presented.

Źródło:

Journal of KONES; 2018, 25, 3; 153-158
1231-4005
2354-0133

Pojawia się w:

Journal of KONES

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 33.

Tytuł:

Analysis of the AOK Plus data and derived hospital network
Analiza danych AOK Plus i zbudowanej na ich podstawie sieci szpitalnej

Autorzy:

Lonc, Agata
Piotrowska, Monika Joanna
Sakowski, Konrad

Powiązania:

https://bibliotekanauki.pl/articles/953416.pdf

Data publikacji:

2019

Wydawca:

Polskie Towarzystwo Matematyczne

Tematy:

healthcare data analysis
overlapping data
healthcare network
multidrug-resistant bacteria

Opis:

We present analysis of admission/discharge data from insurance provider for Saxony and Thuringia (Germany) for years 2010-2016. Study of such data is necessary to derive a structure of healthcare system transfer network, as no patients' transfer data are available. Hospital network is a basis for simulation of multidrug-resistant bacteriae spread allowing to study the effectiveness of disease-control strategies. In this paper, the properties of the dataset under consideration are presented and discussed. Moreover, the resulting interhospital network structure is analyzed.

Źródło:

Mathematica Applicanda; 2019, 47, 1
1730-2668
2299-4009

Pojawia się w:

Mathematica Applicanda

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 34.

Tytuł:

Occurrence and plasmid profiles of multidrug-resistant Enterobacteriaceae isolated from hawked soymilk samples in the Polytechnic of Ibadan Community, Nigeria

Autorzy:

Fadahunsi, I.F.
Babalola, D.O.

Powiązania:

https://bibliotekanauki.pl/articles/2096396.pdf

Data publikacji:

2021

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

occurrence
plasmid profiles
multidrug-resistant Enterobacteriaceae
soymilk
Ibadan Polytechnic
Community

Opis:

This study was conducted to determine the occurrence, antibiotic susceptibility pattern, and plasmid profile of multidrug-resistant (MDR) Enterobacteriaceae isolated from soymilk hawked in the Ibadan Polytechnic Community, Nigeria. Bacterial isolation and identification were performed using a culture-dependent method and biochemical characterization, respectively, while antibiotic susceptibility was tested using the disk diffusion method. Plasmid analysis and curing were performed using standard procedures. The results revealed the following occurrence rate of bacterial species in soymilk samples collected from all axes (South, North, East, West, and Central) of Ibadan Polytechnic: Citrobacter spp., 64%; Klebsiella spp., 7%; Enterobacter spp., Escherichia coli, and Serratia spp., 6% each; Proteus spp., 5%; and Salmonella spp. and Shigella spp., 3% each. The highest heterotrophic bacterial count of 9.3 × 103 CFU/ml was recorded at Ibadan Polytechnic North and South, while the least count (3.2 × 107 CFU/ml) was recorded at Ibadan Polytechnic Central. The highest enteric bacterial count of 1.3 × 103 CFU/ml was recorded in soymilk samples from Ibadan Polytechnic Central, while the least count of 1.7 × 107 CFU/ml was recorded in soymilk samples from Ibadan Polytechnic North. A total of 26% of the isolates showed resistance to cefpodoxime, while 88% of the isolates were susceptible to trimethoprim-sulfamethoxazole. Four of the MDR isolates possessed plasmid bands ranging from 6 to 1 with molecular weights from 2.7 to 17.2 kbp. Enterobacteriaceae such as isolates O14 (Klebsiella spp.) and B10 (E. coli) retained their resistance to antibiotics even after removal of plasmids, while isolates S13 (Citrobacter spp.) and O4 (Shigella spp.) were susceptible to some antibiotics after curing. Conclusively, soymilk sold in the sampled areas was highly contaminated with Enterobacteriaceae, thereby indicating poor hygiene standards of soymilk production.

Źródło:

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2021, 102, 2; 209-223
0860-7796

Pojawia się w:

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 35.

Tytuł:

The analysis of finish tooling influence on contact fatigue of steel applied to sea water pump shafts

Autorzy:

Charchalis, A.
Starosta, R.
Labuda, W.

Powiązania:

https://bibliotekanauki.pl/articles/242173.pdf

Data publikacji:

2011

Wydawca:

Instytut Techniczny Wojsk Lotniczych

Tematy:

contact fatigue
burnishing
corrosion resistant steel
surface layer
angular momentum pumps

Opis:

The article presents the research results referring to the analysis of the influence of finish treatment (lathing, grinding, burnishing) on the contact fatigue of steel applied to marine pump shafts. The research was performed on a roller 25mm in diameter made of X5CrNi18-10 (AISI304 L) stainless steel. The lathing process was carried out by means of a Sandvik Coromant cutting too, the grinding was done by grinding attachment to a lathe, whereas the process of burnishing was performed by SRMD burnisher by Yamato. Within the research, the optimalization of burnishing technological parameters was conducted on account of the minimalization of Ra surface roughness coefficient as well as the maximalization of SU degree of surface layer relative hardness. The multi criteria optimalization conducted by min-max method with regard to minimum surface roughness as well as maximum degree of surface layer hardness demonstrated that burnishing process should be carried out at the following technological parameters: burnishing force 1.1 kN, burnishing speed 35 m/min, feed 0.13 mm/rev. In addition, the influence of the burnisher passes number on the surface layer quality was determined. It is essential for this research to determine the burnishing influence on the service conditions which comprises the electrochemical corrosion research, friction wear and contact fatigue research. The paper will present the research results of contact fatigue examination of samples after finish machining.

Źródło:

Journal of KONES; 2011, 18, 2; 85-92
1231-4005
2354-0133

Pojawia się w:

Journal of KONES

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 36.

Tytuł:

Type IV resistant starch increases cecum short chain fatty acids level in rats

Autorzy:

Le Thanh-Blicharz, Joanna
Anioła, Jacek
Kowalczewski, Przemysław
Przygoński, Krzysztof
Zaborowska, Zofia
Lewandowicz, Grażyna

Powiązania:

https://bibliotekanauki.pl/articles/1039344.pdf

Data publikacji:

2014

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

type IV resistant starch
digestibility
rats
short chain fatty acids
prebiotic

Opis:

Resistant starches are type of dietary fibers. However, their physiological effects depend on the way they resist digestion in the gastrointestinal tract. The objective of this study was to examine the hypothesis that new type of RS4 preparations, of in vitro digestibility of about 50%, obtained by cross-linking and acetylation, acts as a prebiotic by increasing short chain fatty acids content in cecum digesta. The rats were fed with diet containing pregelatinized, cross-linked and acetylated starches as a main carbohydrate source. Pregelatinized, but not chemically modified, potato starch was used in the composition of the control diet. After two weeks of experiment the increase of short chain fatty acids contents in ceceum digesta was observed. The intake of starch A, cross-linked only with adipic acid, resulted in increase of about 40% of short chain fatty acids content, whereas starch PA cross-linked with sodium trimetaphosphate and adipic acid of about 50%. The utmost twofold increase was observed in the case of the production of propionic acid. In contrast, the content of butyric acid increased (12%) only as an effect of consumption of starch PA and even decreased (about 30%) in case of starch A. Both RS4 starches caused an increase of the production of acetic acid by more than 40%. No changes in serum biochemistry, liver cholesterol and organ weights of rats were stated.

Źródło:

Acta Biochimica Polonica; 2014, 61, 1; 109-114
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 37.

Tytuł:

Genetic relatedness, antibiogram and virulence factors of Staphylococcus aureus isolated from bovine mastitis and related human contacts

Autorzy:

Alekish, M.O.
Bani Ismail, Z.
Gharaibeh, M.
Abu-Qatous, L.

Powiązania:

https://bibliotekanauki.pl/articles/2087354.pdf

Data publikacji:

2020

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

intramammary infection
dairy cows
multi-drug resistant S. aureus
antimicrobial resistance

Źródło:

Polish Journal of Veterinary Sciences; 2020, 23, 1; 133-141
1505-1773

Pojawia się w:

Polish Journal of Veterinary Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 38.

Tytuł:

Fatigue life prediction for acid-resistant steel plate under operating loads

Autorzy:

Tomaszewski, T.
Strzelecki, P.
Wachowski, M.
Stopel, M.

Powiązania:

https://bibliotekanauki.pl/articles/200215.pdf

Data publikacji:

2020

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

reliability
macrofractography
finite element analysis
S-N curve
acid-resistant steel

Opis:

The paper evaluates the causes related to the fatigue damage in a conveyor slide plate, exposed to high-frequency cyclic loads. The plate was made of 1.4301 acid-resistant steel. The fractography showed that the plate failure was caused by fatigue crack. A nonlinear analysis of plate deformation was conducted using the finite element method (FEA) in LS-Dyna software. The maximum normal stresses in the plate fracture were used in further analysis. A “fatigue limit” calculated initially using a FITNET procedure was above the maximum stress calculated using FEA. It indicates that the structural features of the plate were selected correctly. The experimental test results for 1.4301 acid-resistant steel were described using a probabilistic Weibull distribution model. Reliability was determined for the obtained S-N curve at 50% and 5% failure probability allowing for the selected coefficients (cycle asymmetry, roughness, variable load) and the history of cyclic loading. Cumulative damage was determined using the Palmgren-Miner hypothesis. The estimated fatigue life was similar to the actual value determined in the operating conditions for the S-N curve at 5% failure probability. For engineering calculations, the S-N curve at max. 5% failure probability is recommended.

Źródło:

Bulletin of the Polish Academy of Sciences. Technical Sciences; 2020, 68, 4; 913-921
0239-7528

Pojawia się w:

Bulletin of the Polish Academy of Sciences. Technical Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 39.

Tytuł:

Wpływ tynku na funkcjonowanie przewodów ognioodpornych w pożarze
The Influence of Plaster on Fire – Resistant Cables Operation in Fire Conditions

Autorzy:

Chybowski, R.
Kustra, P.
Ptak, S.

Powiązania:

https://bibliotekanauki.pl/articles/136468.pdf

Data publikacji:

2013

Wydawca:

Szkoła Główna Służby Pożarniczej

Tematy:

przewody ognioodporne
elektroenergetyczne zagrożenia pożarowe
fire resistant cable
electrical fire safety

Opis:

W artykule przedstawiono wyniki badań wpływu tynku na zachowanie ognioodporności przewodów, tzn. na zapewnienie ciągłości dostawy energii elektrycznej do urządzeń przeciwpożarowych.
The article describes and discusses the research results concerning the influence of plaster on fire – resistant cables operation in fire conditions. Mica, wire insulation that remains even in high temperature, becomes fragile and any impact might cause short circuit, though the plaster itself does not deteriorate cables’ operation.

Źródło:

Zeszyty Naukowe SGSP / Szkoła Główna Służby Pożarniczej; 2013, 1, 45; 49-60
0239-5223

Pojawia się w:

Zeszyty Naukowe SGSP / Szkoła Główna Służby Pożarniczej

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 40.

Tytuł:

The effect of the preheating on to properties of the wear resistant welds
Wpływ podgrzewania wstępnego na właściwości napoin trudnościeralnych

Autorzy:

Gucwa, Marek
Winczek, Jerzy
Mičian, Miloš

Powiązania:

https://bibliotekanauki.pl/articles/115124.pdf

Data publikacji:

2020

Wydawca:

Stowarzyszenie Inżynierów i Techników Mechaników Polskich

Tematy:

napawanie
podgrzewanie
napoina trudnościeralna
hardfacing
pad welding
preheating
wear resistant weld

Opis:

Wear resistant welds are used in many industries when it is necessary to protect machine components and structures against wear caused by operating conditions. Often the main parameter determining the usefulness of these welds is high hardness reaching about 60 HRC. In many cases, after the surfacing process, a mesh of cracks is formed in the surface layer, which can affect the durability of the hard-wearing layers used. The paper presents the analysis of the influence of preheating up to 400 °C on the properties of welds and its effect on the number of cracks in the surface layer. The use of preheating allowed to reduce the number of cracks in the padding weld to 1. The optimum heating temperature was 200 °C, for which the number of cracks have been reduced and the lowest wear was recorded.
Napoiny trudnościeralne są wykorzystywane w wielu gałęziach przemysłu, gdy zachodzi konieczność ochrony elementów maszyn i konstrukcji przed zużyciem wywołanym warunkami eksploatacji. Często głównym parametrem określającym przydatność tych napoin jest wysoka twardość sięgająca ok. 60 HRC. W wielu przypadkach po procesie napawania powstaje w warstwie wierzchniej siatka pęknięć, która może wpływać na trwałość stosowanych warstw trudnościeralnych. W pracy przedstawiono analizę wpływu podgrzewania wstępnego do 400 °C na właściwości napoin oraz jego wpływu na ilość pęknięć w warstwie wierzchniej. Zastosowanie podgrzewania wstępnego pozwoliło zredukować ilość pęknięć w napoinie do 1. Optymalną temperaturą podgrzewania było 200 °C, dla której zanotowano zmniejszenie ilości pęknięć oraz najmniejsze zużycie.

Źródło:

Welding Technology Review; 2020, 92, 2; 7-14
0033-2364
2449-7959

Pojawia się w:

Welding Technology Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 41.

Tytuł:

Evaluation of Productive Value of Several White Cabbage Cultivars Resistant to Clubroot (Plasmodiophora brassicae Wor.)
Ocena wartości użytkowej kilku odmian kapusty głowiastej białej odpornych na kiłę (Plasmodiophora brassicae Wor.)

Autorzy:

Cebula, S.
Mazur, S.
Kalisz, A.

Powiązania:

https://bibliotekanauki.pl/articles/388125.pdf

Data publikacji:

2010

Wydawca:

Towarzystwo Chemii i Inżynierii Ekologicznej

Tematy:

kapusta głowiasta biała
kiła
odmiany odporne
white cabbage
clubroot
resistant cultivars

Opis:

In a 3-year experiment three late cultivars of clubroot-resistant white cabbage: ‘Kilafur F1’, ‘Kilaton F1’ and ‘Kilaxy F1’ were compared with 3 standard cultivars: ‘Bloktor F1’, ‘Kingston F1’ and ‘Novator F1’. The experiment was located on a stand where in the previous year also cabbage was cultivated. During vegetation the degree of plants affected by clubroot was determined. Yield as well as commercial and nutritional quality of cabbage heads were evaluated. In all three years of the experiment it was demonstrated that clubroot-resistant cultivars were not at all affected by Plasmodiophora brassicae pathogen while other cultivars were affected to a varied degree. High commercial yield of clubroot-resistant cultivars and a very good head quality were obtained. In the same conditions, non-resistant cultivars demonstrated a significantly lower yield level.
W trzyletnich badaniach porównywano 3 późne odmiany kapusty głowiastej białej odporne na kiłę: 'Kilafur F1', 'Kilaton F1' i 'Kilaxy F1' oraz 3 standardowe: 'Bloktor F1', 'Kingston F1' i 'Novator F1'. Doświadczenie zlokalizowano na stanowisku, na którym w poprzednim roku była również uprawiana kapusta. W czasie wegetacji szacowano stopień porażenia roślin przez kiłę. Oceniano plonowanie oraz jakość handlową i odżywczą główek kapusty. We wszystkich latach prowadzenia badań wykazano brak jakiegokolwiek porażenia odmian odpornych przez patogena Plasmodiophora brassicae, podczas gdy pozostałe uległy w różnym stopniu infekcji. Uzyskano duży plon handlowy odmian odpornych oraz bardzo dobrą jakość ich główek. W tych samych warunkach uzyskano znacząco niższe plony odmian nieodpornych.

Źródło:

Ecological Chemistry and Engineering. A; 2010, 17, 9; 1083-1088
1898-6188
2084-4530

Pojawia się w:

Ecological Chemistry and Engineering. A

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 42.

Tytuł:

The Attempt of the Low-Cycle Fatigue Life Description of Chosen Creep-Resistant Steels Under Mechanical and Thermal Interactions

Autorzy:

Okrajni, J.
Marek, A.

Powiązania:

https://bibliotekanauki.pl/articles/354016.pdf

Data publikacji:

2017

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

low-cycle fatigue
high temperatures
fatigue life prediction
creep-resistant steels

Opis:

The study focuses on the problem of determination of low-cycle fatigue properties for the chosen group of creep-resistant steels used in the power and chemical industries. It tries to find the parameter which would describe well the fatigue life and take into account mechanical loads and temperature. The results of LCF tests have been presented in the paper. New parameter P has been introduced. This parameter joins a plastic strain range, a stress range and temperature. The fatigue life has been predicted versus parameter P. The comparison of the predicted and observed values of fatigue life shows the agreement between these values. The method of fatigue life prediction formulated in this way is expected to describe the behavior of materials under thermo-mechanical fatigue.

Źródło:

Archives of Metallurgy and Materials; 2017, 62, 4; 2349-2353
1733-3490

Pojawia się w:

Archives of Metallurgy and Materials

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 43.

Tytuł:

Selection of Casting Materials for Working Parts of Machines for the Forestry Sector

Autorzy:

Pirowski, Zenon
Bitka, Adam
Grudzień-Rakoczy, Małgorzata
Małysza, Marcin
Pysz, Stanisław
Wieliczko, Piotr
Wilk-Kołodziejczyk, Dorota

Powiązania:

https://bibliotekanauki.pl/articles/2106604.pdf

Data publikacji:

2022

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

mulching
forestry tools
tribological wear
abrasion-resistant cast steel
hardfacing surface

Opis:

The article was created as a result of the work TECHMATSTRATEG 1 program “Modern Material Technologies” as part of the project with the acronym INNOBIOLAS entitled “Development of innovative working elements of machines in the forestry sector and biomass processing based on high-energy surface modification technologies of the surface layer of cast elements”; agreement No. TECHMATSTRATEG1/348072/2/NCBR/2017. The article discusses the procedure for selecting casting materials that can meet the high operational requirements of working tools of mulching machines: transfer of high static and dynamic loads, resistance to tribological wear, corrosion resistance in various environments. The mulching process was briefly described, then the alloys were selected for experimental tests, model alloys were made and perform material tests were carried out in terms of functional and technological properties. The obtained results allowed to select the alloy where the test castings were made.

Źródło:

Archives of Metallurgy and Materials; 2022, 67, 2; 743--752
1733-3490

Pojawia się w:

Archives of Metallurgy and Materials

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 44.

Tytuł:

Drug-resistant epilepsy and its selected complications in children
Padaczka lekooporna oraz jej wybrane powikłania u dzieci

Autorzy:

Knopek, Magdalena
Iwanicka, Joanna
Boryczka, Grzegorz

Powiązania:

https://bibliotekanauki.pl/articles/33293485.pdf

Data publikacji:

2024-06-24

Wydawca:

Śląski Uniwersytet Medyczny w Katowicach

Tematy:

complications
drug-resistant epilepsy
genetic basis
powikłania
padaczka lekooporna
podłoże genetyczne

Opis:

Drug-resistant epilepsy (DRE) in children is one of the most diagnosed disorders of the nervous system. Despite the availability of pharmacotherapy with various mechanisms of action, drug resistance leads to the inability to achieve the intended therapeutic effect. Considering the complex etiology of this disease entity, there is an urgent need to deepen our knowledge regarding the determinants of DRE, as well as the potential for improving the quality of life for patients and their families. This paper provides an overview and description of the latest advancements and current state of knowledge related to the clinical characteristics, epidemiology, possible complications, and especially genetic basis of DRE in the Polish population of children.
Padaczka lekooporna (drug-resistant epilepsy – DRE) u dzieci jest jedną z najczęściej diagnozowanych chorób układu nerwowego. Pomimo dostępności farmakoterapii o różnych mechanizmach działania lekooporność determinuje brak możliwości osiągnięcia zamierzonego efektu terapeutycznego. Mając na uwadze złożoną etiologię omawianej jednostki chorobowej, istnieje pilna potrzeba zgłębiania wiedzy w zakresie determinantów DRE, jak i możliwości poprawy jakości życia pacjentów oraz ich rodzin. Praca stanowi opis z podsumowaniem najnowszych osiągnięć i aktualnego stanu wiedzy odnoszącego się do charakterystyki klinicznej, epidemiologii, możliwych powikłań, a szczególnie podłoża genetycznego DRE w polskiej populacji dzieci.

Źródło:

Annales Academiae Medicae Silesiensis; 2024, 78; 127-137
1734-025X

Pojawia się w:

Annales Academiae Medicae Silesiensis

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 45.

Tytuł:

Survival outcome and prognostic factors in patients with chemotherapy-naive metastatic castration-resistant prostate cancer treated with abiraterone acetate – real-world experience in Vietnam

Autorzy:

Do, Tu Anh
Nguyen, Thai Hoa Thi
Nguyen, Hau Xuan
Nguyen, Loi Dinh
Nguyen, Chu Van

Powiązania:

https://bibliotekanauki.pl/articles/40555372.pdf

Data publikacji:

2024-06-30

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

abiraterone acetate
metastatic castration-resistant prostate cancer
overall survival
real-world evidence

Opis:

Introduction and aim. In real life, metastatic castration-resistant prostate cancer patients (mCRPC) had more complex clinical presentation than patients in the COU-AA-302 trial. This study primarily aimed to describe the overall survival of chemotherapy-naive mCRPC treated with abiraterone acetate plus prednisone (AAP). Other relevant outcomes and baseline characteristics of these patients were also evaluated. Material and methods. This retrospective, observational study collected data from chemotherapy-naive mCRPC patients treated with AAP in Vietnam. Kaplan-Meier curves were used to estimate time to treatment failure (TTF), and overall survival (OS). The impact of baseline characteristics on OS was explored using univariate and multivariate Cox proportional hazard models. Results. Data from 65 eligible patients were analyzed. The rate of PSA response was 73.8%, median PSA PFS was 10.5 months (95% CI: 7.4–13.6), median TTF was 15 months (95% CI: 11.1–18.9), and median OS was 24.9 months (95% CI: 18.9–30.9). Shorter OS was significantly associated with a higher Gleason score (≥8), shorter time from ADT start to mCRPC (<12 months), visceral metastases, and <50% PSA decline (p<0.05). Conclusion. Abiraterone acetate plus prednisone is well tolerated and effective for chemotherapy-naive mCRPC patients in clinical practice. Moreover, Gleason score, visceral metastasis, time from ADT start to mCRPC, and PSA response are the independent indicators for predicting the OS of mCRPC patients in both univariate and multivariate analyses.

Źródło:

European Journal of Clinical and Experimental Medicine; 2024, 22, 2; 262-269
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 46.

Tytuł:

Diversified role and applications of marine actinomycetes in the field of biology

Autorzy:

Rasool, Ubaid
Hemalatha, S.

Powiązania:

https://bibliotekanauki.pl/articles/1179574.pdf

Data publikacji:

2017

Wydawca:

Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN

Tematy:

Biofouling
Marine actinomycetes; Biologically active metabolites
Nanoparticles
Novel compounds
Resistant pathogenic microorganisms

Opis:

Actinomycetes are the most profitable and biotechnologically valued prokaryotes representing the genera consisting of Streptomyces, Arthrobacter, Actinomyces, Cornyebacterium, Micrococcus, Micromonospora and other diverse species of microorganisms. Actinomycetes represent a group of one of the most powerful secondary metabolite producers which possess a wide range of biological activities. Streptomyces, an important genus under actinomycetes, alone serves as the huge producer of a number of biologically active molecules. This genus possesses a huge potential of synthesizing various different and novel active metabolites. Due to the gradual reduction of the chances of isolation of novel compounds within Streptomyces coming from terrestrial environs resulting in the increase of resistant pathogenic microorganisms, marine actinomycetesmay form a platform for novel drug synthesis, which in-turn may form an extraordinary tool for combating a wide range of resistant microbes. The role of marine actinomycetes extends to diverse fields such as antibiotic production, production of antibacterial and antifungal compounds, synthesis of enzymes and enzyme inhibitors, synthesis of anticancer drugs and various other lifesaving molecules. Marine actinomycetes also play an important role in biofouling and nanoparticle synthesis. Thus speakingsuccinctly, marine actinomycetes are biologically very important as they serve their useful purpose in various fields of biology.

Źródło:

World Scientific News; 2017, 74; 1-14
2392-2192

Pojawia się w:

World Scientific News

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 47.

Tytuł:

The physical modelling of high speed broaching of the heat-resistant steels for studies surface layer quality

Autorzy:

Dvirna, Olha

Powiązania:

https://bibliotekanauki.pl/articles/243378.pdf

Data publikacji:

2019

Wydawca:

Instytut Techniczny Wojsk Lotniczych

Tematy:

physical modelling
high-speed broaching
surface quality
tab grooves
heat-resistant steel

Opis:

The main idea of the work is to create a physical model of high speed broaching heat-resistant materials is used to study the parameters of the surface layer quality. Modelling is a method of mediated cognition, in which the object under study is in some correspondence with the model, and the object-model is capable in some way or another to replace the original at some stages of the cognitive process. Physical modelling is primarily distinguished by the fact that studies are conducted on models with physical similarity, i.e. preserving completely (or at least partially) the nature of the phenomena. The work of the broach can be likened to the work of a number of planning cutter displaced relative to each other by a small amount, which is called lifting (feed per tooth). Therefore, for experimental work, a planning cutter of a special geometric was designed and manufactured – a physical model of a broach, in which geometric, mechanical and dynamic similarity is realized. The article also presents an experimental justification for the use of the created physical model in the study of the surface quality parameters of the, tab grooves of turbine and compressors disks made of heat-resistant materials.

Źródło:

Journal of KONES; 2019, 26, 3; 23-29
1231-4005
2354-0133

Pojawia się w:

Journal of KONES

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 48.

Tytuł:

Molecular docking and pharmacokinetic prediction of phytochemicals from Syzygium cumini in interaction with penicillin-binding protein 2a and erythromycin ribosomal methylase of Staphylococcus aureus

Autorzy:

Shidiki, A.
Vyas, A.

Powiązania:

https://bibliotekanauki.pl/articles/2096259.pdf

Data publikacji:

2022

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

methicillin-resistant S. aureus
penicillin-binding protein 2a
erythromycin ribosomal methylase

Opis:

Background. MRSA and MLSB resistant S. aureus are known as important pathogens, which are responsible for many cases of both hospital and community-acquired infections worldwide. Studying drug discovery from plant sources is regarded as an important prevention strategy regarding these types of infections. Material and methods. Agar well diffusion method was performed for antimicrobial evaluation, LCMS technique used for identification of different compounds, molecular docking performed by application of iGEMDOCK for PBP2a and ERM to plant compounds, and its pharmacokinetic evaluation of ADMET through use of AdmetSAR. Results. Water extract was the most effective against resistant strains of Staphylococcus aureus. Twenty compounds belonging to phenols, flavonoids, organic acids, terpenoids groups were reported. Eighteen plant compounds passed in Lipinski's rule of five. iGEMDOCK revealed diferulic acid has the least binding energy -102.37 kcal/mole to penicillin-binding protein 2a and taxifolin has the least binding energy of -103.12 kcal/mole to erythromycin ribosomal methylase in comparison to control linezolid. These compounds raise the potential for developing potent inhibitors of penicillin-binding protein 2a and erythromycin ribosomal methylase for drug development. ADMET properties revealed that eighteen studied compounds were found in category III and IV with non-toxic properties except two butin and taxifolin found in category II with toxic properties. Conclusions. It can be concluded that diferulic acid and taxifolin compounds provide the best inhibitor effect to PBP2a and ERM protein for inhibition of MRSA and MLSB resistant strains of S. aureus through the application of molecular docking, leading to a lead drug candidate for the treatment of diseases.

Źródło:

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2022, 103, 1; 5-18
0860-7796

Pojawia się w:

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 49.

Tytuł:

Effects of regular physical activity on pain, anxiety, and depression in patients with treatment-resistant arterial hypertension

Autorzy:

Kruk, Piotr
Nowicki, Michał

Powiązania:

https://bibliotekanauki.pl/articles/552578.pdf

Data publikacji:

2016

Wydawca:

Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych

Tematy:

depression
pain
anxiety
physical activity
ambulatory blood pressure monitoring
resistant arterial hypertension

Źródło:

Family Medicine & Primary Care Review; 2016, 3; 268-273
1734-3402

Pojawia się w:

Family Medicine & Primary Care Review

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 50.

Tytuł:

Ocena strawności diet zawierających skrobie modyfikowane typu RS w badaniach na szczurach
Digestibility of diets containing RS modified starches assessment in rats

Autorzy:

Le Thanh-Blicharz, Joanna
Anioła, Jacek
Walkowski, Aleksander
Lewandowicz, Grażyna

Powiązania:

https://bibliotekanauki.pl/articles/2198392.pdf

Data publikacji:

2012-12-31

Wydawca:

Instytut Hodowli i Aklimatyzacji Roślin

Tematy:

badania in vivo
skrobia oporna
strawność
digestibility
in vivo researches
resistant starch

Opis:

W pracy określono wpływ skrobi opornej na strawność in vivo w badaniach na szczurach outbredowych Wistar. W doświadczeniu wykorzystano 40 samców w wieku 12 tygodni. Zwierzęta karmiono czterema rodzajami diet: kontrolną ze wstępnie kleikowaną skrobią ziemniaczaną suszona na walcach (SW), oraz trzema z dodatkiem różnych preparatów modyfikowanych skrobi opornych (AO, WT, RS). Wykonano oznaczenia parametrów ogólno żywieniowych i wzrostowych oraz oznaczono strawność in vivo metodą klasyczną. Wykazano, że 50% dodatek preparatów opornych na enzymy amylolityczne skrobi modyfikowanych do diet szczurów rasy Wistar spowodował zwiększenie zawartości wody w kale, co świadczy o zdolności tychże preparatów do wiązania wody, a co za tym idzie przyspieszonego pasażu treści pokarmowej czego wynikiem jest jego potencjalne działanie dietetyczne. Oznaczona metodą bilansową strawność diety i jej głównych składników, tzn. białka, tłuszczu oraz węglowodanów (skrobi) była nieznacznie zróżnicowana pomiędzy badanymi grupami. Najniższą strawność in vivo odnotowano w przypadku handlowego preparatu RS3.
The objective of the paper was to assess the effect of RS modified starch on in vivo digestibility in Wistar rats. In the experiment, 40 12-week-old rats were used. Animals were fed 4 different diets: control pregelatinised potato starch and 3 diets with resistant starches (AO, WT, RS). Determination of nutritional and growth parameters have been carried out. The in vivo digestibility determined by standard method was made as well. It was found that 50% addition of starch preparations resistant to amylolitycal enzymes to the diet increased the water content in fecal. It proves that RS preparations are able to bind water and accelerate the feed passage. Digestibility and protein, fat and sugars content measured by balance method were hardly distinguishable between analyzed diets. The preparation marked RS-3 showed the lowest digestibility.

Źródło:

Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin; 2012, 266; 57-64
0373-7837
2657-8913

Pojawia się w:

Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin

Dostawca treści:

Biblioteka Nauki

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