Temat: resistant - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: The role of additional correction methods of insufficient adherence to treatment for effective blood pressure control in patients with resistant arterial hypertension
Autorzy:: Voloshyna, O.
Zbitnieva, V.
Busel, S.
Chaika, A.
Samorukova, V.
Dychko, T.
Powiązania:: https://bibliotekanauki.pl/articles/765449.pdf
Data publikacji:: 2016
Wydawca:: Uniwersytet Mikołaja Kopernika w Toruniu. Wydział Nauk o Ziemi i Gospodarki Przestrzennej. Katedra Kultury Fizycznej
Tematy:: resistant hypertension, pseudo-resistant hypertension, uncontrolled blood pressure, adherence
Opis:: Voloshyna O., Zbitnieva V., Busel S., Chaika A., Samorukova V., Dychko T. The role of additional correction methods of insufficient adherence to treatment for effective blood pressure control in patients with resistant arterial hypertension. Journal of Education, Health and Sport. 2016;6(12):857-865. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.252818http://ojs.ukw.edu.pl/index.php/johs/article/view/4184 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 754 (09.12.2016).754 Journal of Education, Health and Sport eISSN 2391-8306 7© The Author (s) 2016;This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercialuse, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper.Received: 05.12.2016. Revised 20.12.2016. Accepted: 25.12.2016. УДК 616.12-008.331.1-036.8 THE ROLE OF ADDITIONAL CORRECTION METHODS OF INSUFFICIENT ADHERENCE TO TREATMENT FOR EFFECTIVE BLOOD PRESSURE CONTROL IN PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION O. Voloshyna, V. Zbitnieva, S. Busel, A. Chaika, V. Samorukova, T. Dychko Odessa National Medical University, Ukraine AbstractThe article considers the results of applying the different correction methods of insufficient adherence to treatment in patients with resistant and pseudo-resistant arterial hypertension on the background of the optimization of antihypertensive therapy in the effective blood pressure control by a doctor and a patient.Keywords: resistant hypertension, pseudo-resistant hypertension, uncontrolled blood pressure, adherence
Źródło:: Journal of Education, Health and Sport; 2016, 6, 12
2391-8306
Pojawia się w:: Journal of Education, Health and Sport
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Dietary resistant dextrins positively modulate fecal and cecal microbiota composition in young rats
Autorzy:: Śliżewska, Katarzyna
Libudzisz, Zdzisława
Barczyńska, Renata
Kapuśniak, Janusz
Zduńczyk, Zenon
Juśkiewicz, Jerzy
Powiązania:: https://bibliotekanauki.pl/articles/1038883.pdf
Data publikacji:: 2015
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: resistant dextrin
microflora
rats
Opis:: The objective of the present study was to demonstrate the effect of dietary resistant dextrins, as potential prebiotics, on the intestinal microflora of young rats. Enzyme-resistant dextrin, prepared by heating of potato starch in the presence of hydrochloric (0.1% dsb) and tartaric (40% dsb) acid at 130ºC for 2 h (CA-dextrin). The experiment was performed on 24 Wistar male rats at 3-wk of age, divided by analogues in three experimental groups (control, starch and dextrin). Analyses determined the overall bacterial counts and the counts of Lactobacillus, Bifidobacterium, Bacteroides and Clostridium strains within the feces and cecal contents of rats using fluorescence in situ hybridization method. CA-dextrin had no effect on primary growth indicators (body weight, body weight gain, dietary consumption) or the mass of the small intestine and the cecum, but dextrins caused a reduction in pH and the concentration of ammonia within the cecal contents. That supplementation of diet with resistant dextrins had a positive effect on composition of intestinal microflora in rats. It increased the counts of Bifidobacterium and Lactobacillus strains both in the feces and in the cecum. Moreover, it reduced the counts of Clostridium and Bacteroides strains. These results may suggest that resistant dextrins exerted a prebiotic-like effect in the large intestine.
Źródło:: Acta Biochimica Polonica; 2015, 62, 4; 677-681
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: The citric acid-modified, enzyme-resistant dextrin from potato starch as a potential prebiotic
Autorzy:: Śliżewska, Katarzyna
Powiązania:: https://bibliotekanauki.pl/articles/1039464.pdf
Data publikacji:: 2013
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: resistant dextrin
prebiotic
intestinal bacteria
Opis:: In the present study, enzyme-resistant dextrin, prepared by heating of potato starch in the presence of hydrochloric (0.1% dsb) and citric (0.1% dsb) acid at 130ºC for 3 h (CA-dextrin), was tested as a source of carbon for probiotic lactobacilli and bifidobacteria cultured with intestinal bacteria isolated from feces of three healthy 70-year old volunteers. The dynamics of growth of bacterial monocultures in broth containing citric acid (CA)-modified dextrin were estimated. It was also investigated whether lactobacilli and bifidobacteria cultured with intestinal bacteria in the presence of resistant dextrin would be able to dominate the intestinal isolates. Prebiotic fermentation of resistant dextrin was analyzed using prebiotic index (PI). In co-cultures of intestinal and probiotic bacteria, the environment was found to be dominated by the probiotic strains of Bifidobacterium and Lactobacillus, which is a beneficial effect.
Źródło:: Acta Biochimica Polonica; 2013, 60, 4; 671-675
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Projektowanie włóknistych wyrobów nietkanych, przeznaczonych na warstwy przeciwuderzeniowe
Developing the non-woven, fibrous goods dedicated for impact-resistant layers
Autorzy:: Maklewska, E.
Powiązania:: https://bibliotekanauki.pl/articles/238069.pdf
Data publikacji:: 2008
Wydawca:: Instytut Technologii Bezpieczeństwa Moratex
Tematy:: warstwa przeciwuderzeniowa
ochraniacze przeciwuderzeniowe
włókno kokosowe
impact-resistant layer
impact-resistant protectors
coconut fibres
Opis:: W wyniku pracy badawczej opracowano materiał włóknisty, o strukturze przestrzennej, przeznaczony na warstwy przeciwuderzeniowe w ochraniaczach stosowanych w ubiorach i wyposażeniu ochronnym osób uprawiających sporty urazogenne. Materiał otrzymano w wyniku nowatorskiego zastosowania proekologicznych włókien kokosowych, o dużej zawartości lignin oraz środka wiążącego z udziałem kopolimeru etylenu i octanu winylu z dodatkiem środków porotwórczych. Opracowany materiał został zgłoszony pod nazwą Impactex w 2005 r. do Urzędu Patentowego jako projekt wynalazczy nr P-374169. Jego skuteczność w zakresie tłumienia energii uderzenia potwierdziły rezultaty badań przeprowadzonych na stanowisku, służącym do oceny zdolności amortyzacji uderzenia ochraniaczy sportowych. Oryginalna konstrukcja stanowiska umożliwia taka ocenę przy jednoczesnym zastosowaniu dwóch metod badawczych. Została również zaproponowana nowatorska metoda oceny rozkładu siły pod ochraniaczem, podczas badań na stanowisku, wykorzystująca cienkościenne czujniki ciśnienia. Procedura badań ochraniaczy przeciwuderzeniowych przewiduje także, możliwość porównania wytypowanych wskaźników z przyjętymi w literaturze biomechanicznej wybranymi kryteriami dla określania poziomu ludzkiej tolerancji na uszkodzenie danego obszaru ciała.
As a result of research work, the fibrous material featuring 3D-structure has been developed and dedicated for impact-resistant layers of protectors applied in clothing and protective equipment for individuals practising traumatic sports. The material was gained by innovative applying eco-friendly coconut fibres, reach of lignin and binding means with co-polymer of ethylene and vinyl acetate with porogenous agent. The developed material has been submitted in 2005 under the name of IMPACTEX to the Patent Office as the invention project no. P-374169. Its efficiency on attenuating the energy of hitting was confirmed by the results of tests executed on a workstation designed for assaying the sports protectors' capability to suppress impacts. The original design of the workstation allows for such an assay with two test methods applied simultaneously. An innovative method of assaying the force distribution under the protector was also suggested, while testing on the workstation with thin-walled pressure sensors used. The testing procedure for impact-resistant protectors includes also the possibility of comparison selected indices to the selected criteria accepted by biomechanical bibliography to determine level of human toleration for injury of given area of body.
Źródło:: Techniczne Wyroby Włókiennicze; 2008, R. 16, nr 3/4, 3/4; 78-86
1230-7491
Pojawia się w:: Techniczne Wyroby Włókiennicze
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Comparative assessment of heat insulation properties of thermal resistant paints with use of infrared camera
Autorzy:: Kruczek, T.
Szczygieł, I.
Kruczek, G.
Kowalczyk, P.
Powiązania:: https://bibliotekanauki.pl/articles/114646.pdf
Data publikacji:: 2017
Wydawca:: Stowarzyszenie Inżynierów i Techników Mechaników Polskich
Tematy:: thermovision infrared measurements
thermal resistant paint
Opis:: To reduce heat losses from buildings various methods are used. One of them is applying so called “thermal resistant paints”. These paints can be put in principle on the inner but also on outer surfaces of building external walls. The aforementioned paints are put on a surface in the similar way as other paints in building construction technology and form a thin insulation layer. The acting of this paints consists in causing a noticeable temperature drop within this layer and simultaneously on the wall surface. This work presents the experimental rig, measurement procedures and selected measurement results.
Źródło:: Measurement Automation Monitoring; 2017, 63, 3; 98-101
2450-2855
Pojawia się w:: Measurement Automation Monitoring
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 6.

Tytuł:: Antibiotic resistance of bacteria and incidence of carbapenamase-coding genes blaPER and blaGES in isolates from wastewater treatment plants
Autorzy:: Jendrzejewska, Natalia
Powiązania:: https://bibliotekanauki.pl/articles/1178215.pdf
Data publikacji:: 2018
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:: antibiotics-resistant bacteria
genes
pollution
wastewater
Opis:: The increase in number of antibiotic resistant bacteria poses a serious environmental and health problem. The development of microbial resistance is intensified by the widespread use of antibiotics in medicine, veterinary, farming and aquaculture. The wastewater treatment plants receiving the wastewater from hospitals, slaughterhouses, farms, pharmaceutical industry and houses can be potential places of spreading of antibiotic resistant genes. The molecular mechanisms of the bacterial resistance, including the horizontal transfer of antibiotic resistant genes and the presence of mobile genetic elements can be responsible for the increase in antibiotic resistance during wastewater treatment. The aim of this study was to analyze the phenomenon of bacterial resistance to selected β-lactam antibiotics (ESBL) by detecting the genes that determine this resistance. The PCR method was used to analyze the occurrence of two genes: blaPER and blaGES in wastewater samples. It was revealed that the resistant/total bacteria ratio was significantly higher in the effluent compared with the influent wastewater. Genes blaPER and blaGES were isolated from several strains predominating in both aeration tank (5% and 20% respectively) and effluent wastewater (15% and 12% respectively).
Źródło:: World Scientific News; 2018, 93; 30-39
2392-2192
Pojawia się w:: World Scientific News
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 7.

Tytuł:: Analyses of the genes involved in disease development to construct disease-resistant plants by genetic engineering
Autorzy:: Tsuyumu, S.
Hirata, H.
Powiązania:: https://bibliotekanauki.pl/articles/385202.pdf
Data publikacji:: 2009
Wydawca:: Sieć Badawcza Łukasiewicz - Przemysłowy Instytut Automatyki i Pomiarów
Tematy:: genes
analyses
disease-resistant
genetic engineering
Opis:: Many genes responsible for the disease development were identified from transposon-tagging, micro-array, and proteomics analyses. Here, we introduce especially the genes required for the initiation of pathogenic life cycle, the suppression of otherwise induction of resistance responses, massive production of virulence factors in plant pathogenic bacteria and an unique plant gene responsible for the development of canker symptom. From these findings we came to raise some new strategies to construct disease-resistant plants by genetic engineering.
Źródło:: Journal of Automation Mobile Robotics and Intelligent Systems; 2009, 3, 4; 84-86
1897-8649
2080-2145
Pojawia się w:: Journal of Automation Mobile Robotics and Intelligent Systems
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 8.

Tytuł:: Acinetobacter Baumannii Nosocomial Infections
Autorzy:: Sieniawski, Karol
Kaczka, Krzysztof
Rucińska, Monika
Gagis, Ludmiła
Pomorski, Lech
Powiązania:: https://bibliotekanauki.pl/articles/1396395.pdf
Data publikacji:: 2013-09-01
Wydawca:: Index Copernicus International
Tematy:: Acinetobacter baumannii
nosocomial infections
multidrug-resistant
Opis:: Nosocomial infections caused by strains Acinetobacter baumannii strands are a growing clinical problem. The occurrence of multidrug-resistant strands is observed and that limits the ways of therapy considerably. The aim of the study was to determine the rate of infection and susceptibility spectrum of the species Acinetobacter baumannii isolated from patients treated at Maria Skłodowska-Curie Memorial Hospital in Zgierz with particular emphasis on surgical wards. Materials and methods. The material consisted of Acinetobacter baumannii isolates were obtained from samples of materials from patients treated at Maria Skłodowska-Curie Memorial Hospital in Zgierz from January to December 2011. Isolated bacterial strains were cultured at microbiological substrates. Isolates were identified to species using the VITEK 2 GN card (bioMérieux) and Vitek 2 automated system (bioMérieux). Susceptibility towards antibiotics of particular strains was determined by the means of AST NO 93 card. In the case of resistance towards carbapenem, the MIC was marked by E-test with Mueller Hinton substrate. The occurrence of MBL was verified by the means of disc system with Mueller Hinton substrate. Results. We have shown that total number of Acinetobacter baumannii infections at hospital was 140 (10,31% of total results of cultures). Percentage of Acinetobacter baumannii infections at wards: Intensive Care Unit 48%, Surgical Departments 20%, Internal Diseases Department 16%, Neurology 13%, other wards - 3%. The susceptibility percentage of Acinetobacter Baumannii against antibiotics: colistin 90%, imipenem 64%, meropenem 43%, ampicillin-sulbactam 28%, amikacin 27%, gentamicin 24%, cefepime 9%, ceftazidime 7%, ciprofloxacin 7% Conclusions. Acinetobacter baumannii infections are a significant proportion of nosocomial infections. Most relate to surgical wards and ICUs. Acinetobacter baumannii is resistant against most antibiotics. The highest percentage of sensitivity demonstrated for colistin and carbapenems
Źródło:: Polish Journal of Surgery; 2013, 85, 9; 483-490
0032-373X
2299-2847
Pojawia się w:: Polish Journal of Surgery
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 9.

Tytuł:: Past, Present & Future of Thermally Stable Explosives
Autorzy:: Agrawal, J. P.
Powiązania:: https://bibliotekanauki.pl/articles/358166.pdf
Data publikacji:: 2012
Wydawca:: Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego
Tematy:: explosives
thermally stable explosives
heat-resistant explosives
Opis:: Explosives with improved high temperature properties are usually referred to as 'thermally stable explosives' or heat-resistant explosives. They are safer, more reliable and more stable at elevated temperatures and find applications in modern Ordnance, Space and Nuclear applications. This paper discusses general approaches for the synthesis of thermally stable explosives, their properties and specific applications. This paper also gives a comparative account of the properties of some of the most thermally stable explosives reported so far. Based on their ease of synthesis, properties (mainly stability at elevated temperatures and insensitivity to impact, friction and percussion) and cost, TATB is considered as a benchmark, thermally stable explosive which is discussed in detail. Furthermore, this review also describes the synthesis and properties of BTDAONAB which does not melt below 550 °C and is considered a better thermally stable explosive than TATB. Finally, a new line of research in this field in the years to come is also highlighted.
Źródło:: Central European Journal of Energetic Materials; 2012, 9, 3; 273-290
1733-7178
Pojawia się w:: Central European Journal of Energetic Materials
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 10.

Tytuł:: Degradation of the gas turbine blade coating and its influence on the microstructure state of the superalloy
Autorzy:: Błachnio, J.
Kułaszka, A.
Zasada, D.
Powiązania:: https://bibliotekanauki.pl/articles/244112.pdf
Data publikacji:: 2015
Wydawca:: Instytut Techniczny Wojsk Lotniczych
Tematy:: turbine
blade
heat-resistant coating
technical condition
Opis:: The technical condition of the blades has a critical influence on the reliability and life span of a gas turbine and an engine into which it is built in. The main causes of blade damage are overheating, creeping, thermal fatigue, high temperature corrosion, etc. It is often caused by adverse operational conditions or manufacturing defect, e.g. using insufficiently durable types of heat-resistant protective coatings or applied in an improper manner on the blade material. Reaction of coatings and blade material to mechanical and thermal loads depends mainly on the operating temperature of the turbine. Selection of a protective coating and material to manufacture a blade with an assumed strength must take into account its mechanical and thermal properties at maximum aerofoil temperature. The article presents characteristic forms of operational damages to the gas turbine blades of a turbojet aero engine. Distinguished were operational factors and their influence on the technical condition of coatings during the engine operation period. An influence of excess exhaust gas temperature on the condition of the heat-resistant blade layer was shown. Shown were also results of morphology tests of coating degradation types. Results of micro-structure tests of the blade superalloy after damage to the heat-resistant coating were also presented.
Źródło:: Journal of KONES; 2015, 22, 2; 17-24
1231-4005
2354-0133
Pojawia się w:: Journal of KONES
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 11.

Tytuł:: A Comparism of the Response of Some Pearl Millest (Pennisetum glaucum (L.) R. BR) Hybrids and Their Parents to Downy Mildew (Sclerospora graminicola) Infestation in Bakura and Zaria (North-western Nigeria)
Autorzy:: Maryam, Ati H.
Angarawai, I. I.
Powiązania:: https://bibliotekanauki.pl/articles/1178552.pdf
Data publikacji:: 2017
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:: downy mildew
hybrids
obligate biotrophs
resistant
tolerance
Opis:: Downy mildew (Sclerospora graminicola (Sacc) Schroet.) of pearl millet [Pennisetum glaucum (L.) R.Br.] is a devastating disease that has greatly led to grain yield loss in Nigeria. A field experiment was carried out in 2010 at Bakura (Zamfara State) and Zaria (Kaduna State) in North West Nigeria. The objective of this paper was to evaluate downy mildew resistance in some pearl millet using Complete Randomized Block Design. Four resistant male varieties (PEO5532, SOSATC88, P1449 and DMR15) and four susceptible female varieties (BDP1, MOP1, LCIC9702 and PEO5984 were used in this study. The resistant varieties were crossed with the susceptible varieties using North Carolina design 11 for the mating to form sixteen (F1) hybrids. The F1 hybrids were further evaluated along with their parents for downy mildew resistance, grain yield and other agronomic traits (such as: Plant height, panicle height, number of tillers per plant, panicle diameter and number panicles per plot). The resistant male parents were found to be susceptible while none of the hybrids was resistant to downy mildew. However, the degree of incidence and severity of downy mildew disease defer in the two locations. The hybrids exhibited tolerance to downy mildew disease and their yields were higher than their parents. The analysis of variance (one tale ANOVA or which one?) showed highly significant difference among parents and hybrids for all agronomic characters except disease severity and number of tillers per plant. Location × genotype interaction effects were only significant for grain yield and number of panicles per plot.
Źródło:: World Scientific News; 2017, 70, 2; 252-264
2392-2192
Pojawia się w:: World Scientific News
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 12.

Tytuł:: Occurrence of high-level aminoglycoside resistance (HLAR) among Enterococcus species strains
Autorzy:: Sieńko, A.
Wieczorek, P.
Wieczorek, A.
Sacha, P.
Majewski, P.
Ojdana, D.
Michalska, A.
Tryniszewska, E.
Powiązania:: https://bibliotekanauki.pl/articles/1916469.pdf
Data publikacji:: 2014
Wydawca:: Uniwersytet Medyczny w Białymstoku
Tematy:: enterococcus
aminoglycoside resistance
vancomycin-resistant
enterococcus (VRE)
Opis:: Purpose: Today, Enterococcus species are one of the most frequent etiological agents in nosocomial infections. The aim of this study was to determine the susceptibility to antibiotics and the prevalence of high-level aminoglycoside resistance (HLAR) among Enterococcus strains. Materials and methods: The susceptibility of 85 isolates of Enterococcus (47 E. faecalis and 38 E. faecium) was determined using the disk diffusion method. The results were interpreted according to European Committee on Antimicrobial Suscepti-bility Testing (EUCAST) guidelines. PASW Statistics 17.0 was used for statistical analysis. Results: E. faecalis strains showed the highest susceptibility to ampicillin, tigecycline, vanco-mycin, imipenem, and linezolid and E. faecium to linezolid, tigecycline, and quinupristin/dalfopristin. Among all tested strains, high-level gentamicin resistance (HLGR) was found in 4% of E. faecalis and 8% of E. faecium strains, high-level strepto-mycin resistance (HLSR) in 45% and 42%, and HLAR in 50% and 32% of strains, respectively. HLGR was detected only in vancomycin-resistant Enterococcus (VRE)− strains (12%), while HLSR in 76.9% of VRE+ and 24% of VRE− strains, and HLAR in 23.1% of VRE+ and 64% of VRE− strains. The tested strains were also divided into two groups: HLSR+ and HLAR+. In both groups, statistically significant susceptibility differences (p<0.05) were found for ampicillin, imipenem and trimethoprim/sulfamethoxazole. The most frequent antibiotic resistance profile among E. faecalis strains was SR (resistance phenotype to strepto-mycin), and among E. faecium, AMPR, IMPR, CNR, SR, SXTR (ampicillin, imipenem, gentamicin, streptomycin, trimethoprim/sulfamethoxazole). Conclusions: This study showed the slowly increasing prevalence of HLAR and resistance to newer antibiotics (linezolid and tigecycline) among Enterococcus strains. It is necessary to search for new directions in the treatment of enterococcal infections.
Źródło:: Progress in Health Sciences; 2014, 4, 1; 179-187
2083-1617
Pojawia się w:: Progress in Health Sciences
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 13.

Tytuł:: Apalutamide in the treatment of a patient with non-metastatic castration-resistant prostate cancer
Autorzy:: Dziura, Robert
Powiązania:: https://bibliotekanauki.pl/articles/22676763.pdf
Data publikacji:: 2023-03-31
Wydawca:: Medical Education
Tematy:: prostate cancer
castration-resistant
androgen receptor inhibitor
Opis:: The treatment of patients with prostate cancer, who do not qualify for the radical therapy is based on the use of surgical or pharmacological castration methods. The effectiveness of the so-called androgen deprivation tends to decrease over time. Even in the absence of distant metastases on imaging studies, the resistance for the hormonal castration may be developed. At this moment, the use of new generation androgen receptor inhibitors may reduce the risk of metastases or death. The paper presents a case report of a patient with prostate cancer without distant metastases who started therapy with apalutamide at the moment of developing re-sistance to the pharmacological castration.
Źródło:: OncoReview; 2023, 13, 1; 20-23
2450-6125
Pojawia się w:: OncoReview
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 14.

Tytuł:: Apalutamide as a new option for postponing metastatic disease in hormone -resistant patients with biochemical recurrence in prostate cancer
Autorzy:: Dąbek, Bartosz
Powiązania:: https://bibliotekanauki.pl/articles/22676825.pdf
Data publikacji:: 2023-04-04
Wydawca:: Medical Education
Tematy:: non-metastatic castration-resistant prostate cancer
apalutamide
Opis:: Treatment of non-metastatic castration-resistant prostate cancer is a radically new option for cancer patients. Novel anti-hormonal therapy not only improves metastasis free survival but overall survival times and positively impacts quality of life. This case shows how apalutamide lowered tPSA level and postponed metastatic disease.
Źródło:: OncoReview; 2023, 13, 1; 24-26
2450-6125
Pojawia się w:: OncoReview
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 15.

Tytuł:: Pollution in Shatt Al-Arab River near Hospital Wastewater Disposal – Detection of Pharmaceutical Compounds, Isolation and Identification of Drug-Resistant Bacteria
Autorzy:: Alsaad, Noor Kadhim
Almansoory, Asia Fadhile
Al-Baldawi, Israa Abdulwahab
Powiązania:: https://bibliotekanauki.pl/articles/2202283.pdf
Data publikacji:: 2022
Wydawca:: Polskie Towarzystwo Inżynierii Ekologicznej
Tematy:: resistant bacteria
well diffusion
river
pharmaceutical
micropollutants
Opis:: Pharmaceutical compounds have been introduced into the aquatic ecosystems in multiple ways and sources, which negatively affects the health of the environment and humans. The river near the hospital sewage disposal is host environment for drug-resistant bacteria (DRB). In this context, the aim of the research was to detect the presence of pharmaceuticals in hospital wastewater, after treatment, at river point followed by isolation of bacteria and test for resistant pharmaceutical compound. Fifteen species of bacteria isolated by angiogenic methods were identified and tested using the well diffusion test to determine the resistance of selected bacteria to ibuprofen by survival assessment. This study showed that the ibuprofen detected by GC-mass was available in all selected points at a concentration of 3 to 120 mg/L. Lecuco. mesen.cremris and Koc.rosea have a high ability to break down the ibuprofen compound. Thus, the bacteria isolated from hospital wastewater can biologically degrade ibuprofen.
Źródło:: Journal of Ecological Engineering; 2022, 23, 12; 29--36
2299-8993
Pojawia się w:: Journal of Ecological Engineering
Dostawca treści:: Biblioteka Nauki

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