Temat: resistant - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: The role of additional correction methods of insufficient adherence to treatment for effective blood pressure control in patients with resistant arterial hypertension
Autorzy:: Voloshyna, O.
Zbitnieva, V.
Busel, S.
Chaika, A.
Samorukova, V.
Dychko, T.
Powiązania:: https://bibliotekanauki.pl/articles/765449.pdf
Data publikacji:: 2016
Wydawca:: Uniwersytet Mikołaja Kopernika w Toruniu. Wydział Nauk o Ziemi i Gospodarki Przestrzennej. Katedra Kultury Fizycznej
Tematy:: resistant hypertension, pseudo-resistant hypertension, uncontrolled blood pressure, adherence
Opis:: Voloshyna O., Zbitnieva V., Busel S., Chaika A., Samorukova V., Dychko T. The role of additional correction methods of insufficient adherence to treatment for effective blood pressure control in patients with resistant arterial hypertension. Journal of Education, Health and Sport. 2016;6(12):857-865. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.252818http://ojs.ukw.edu.pl/index.php/johs/article/view/4184 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 754 (09.12.2016).754 Journal of Education, Health and Sport eISSN 2391-8306 7© The Author (s) 2016;This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercialuse, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper.Received: 05.12.2016. Revised 20.12.2016. Accepted: 25.12.2016. УДК 616.12-008.331.1-036.8 THE ROLE OF ADDITIONAL CORRECTION METHODS OF INSUFFICIENT ADHERENCE TO TREATMENT FOR EFFECTIVE BLOOD PRESSURE CONTROL IN PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION O. Voloshyna, V. Zbitnieva, S. Busel, A. Chaika, V. Samorukova, T. Dychko Odessa National Medical University, Ukraine AbstractThe article considers the results of applying the different correction methods of insufficient adherence to treatment in patients with resistant and pseudo-resistant arterial hypertension on the background of the optimization of antihypertensive therapy in the effective blood pressure control by a doctor and a patient.Keywords: resistant hypertension, pseudo-resistant hypertension, uncontrolled blood pressure, adherence
Źródło:: Journal of Education, Health and Sport; 2016, 6, 12
2391-8306
Pojawia się w:: Journal of Education, Health and Sport
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Dietary resistant dextrins positively modulate fecal and cecal microbiota composition in young rats
Autorzy:: Śliżewska, Katarzyna
Libudzisz, Zdzisława
Barczyńska, Renata
Kapuśniak, Janusz
Zduńczyk, Zenon
Juśkiewicz, Jerzy
Powiązania:: https://bibliotekanauki.pl/articles/1038883.pdf
Data publikacji:: 2015
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: resistant dextrin
microflora
rats
Opis:: The objective of the present study was to demonstrate the effect of dietary resistant dextrins, as potential prebiotics, on the intestinal microflora of young rats. Enzyme-resistant dextrin, prepared by heating of potato starch in the presence of hydrochloric (0.1% dsb) and tartaric (40% dsb) acid at 130ºC for 2 h (CA-dextrin). The experiment was performed on 24 Wistar male rats at 3-wk of age, divided by analogues in three experimental groups (control, starch and dextrin). Analyses determined the overall bacterial counts and the counts of Lactobacillus, Bifidobacterium, Bacteroides and Clostridium strains within the feces and cecal contents of rats using fluorescence in situ hybridization method. CA-dextrin had no effect on primary growth indicators (body weight, body weight gain, dietary consumption) or the mass of the small intestine and the cecum, but dextrins caused a reduction in pH and the concentration of ammonia within the cecal contents. That supplementation of diet with resistant dextrins had a positive effect on composition of intestinal microflora in rats. It increased the counts of Bifidobacterium and Lactobacillus strains both in the feces and in the cecum. Moreover, it reduced the counts of Clostridium and Bacteroides strains. These results may suggest that resistant dextrins exerted a prebiotic-like effect in the large intestine.
Źródło:: Acta Biochimica Polonica; 2015, 62, 4; 677-681
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: The citric acid-modified, enzyme-resistant dextrin from potato starch as a potential prebiotic
Autorzy:: Śliżewska, Katarzyna
Powiązania:: https://bibliotekanauki.pl/articles/1039464.pdf
Data publikacji:: 2013
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: resistant dextrin
prebiotic
intestinal bacteria
Opis:: In the present study, enzyme-resistant dextrin, prepared by heating of potato starch in the presence of hydrochloric (0.1% dsb) and citric (0.1% dsb) acid at 130ºC for 3 h (CA-dextrin), was tested as a source of carbon for probiotic lactobacilli and bifidobacteria cultured with intestinal bacteria isolated from feces of three healthy 70-year old volunteers. The dynamics of growth of bacterial monocultures in broth containing citric acid (CA)-modified dextrin were estimated. It was also investigated whether lactobacilli and bifidobacteria cultured with intestinal bacteria in the presence of resistant dextrin would be able to dominate the intestinal isolates. Prebiotic fermentation of resistant dextrin was analyzed using prebiotic index (PI). In co-cultures of intestinal and probiotic bacteria, the environment was found to be dominated by the probiotic strains of Bifidobacterium and Lactobacillus, which is a beneficial effect.
Źródło:: Acta Biochimica Polonica; 2013, 60, 4; 671-675
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Projektowanie włóknistych wyrobów nietkanych, przeznaczonych na warstwy przeciwuderzeniowe
Developing the non-woven, fibrous goods dedicated for impact-resistant layers
Autorzy:: Maklewska, E.
Powiązania:: https://bibliotekanauki.pl/articles/238069.pdf
Data publikacji:: 2008
Wydawca:: Instytut Technologii Bezpieczeństwa Moratex
Tematy:: warstwa przeciwuderzeniowa
ochraniacze przeciwuderzeniowe
włókno kokosowe
impact-resistant layer
impact-resistant protectors
coconut fibres
Opis:: W wyniku pracy badawczej opracowano materiał włóknisty, o strukturze przestrzennej, przeznaczony na warstwy przeciwuderzeniowe w ochraniaczach stosowanych w ubiorach i wyposażeniu ochronnym osób uprawiających sporty urazogenne. Materiał otrzymano w wyniku nowatorskiego zastosowania proekologicznych włókien kokosowych, o dużej zawartości lignin oraz środka wiążącego z udziałem kopolimeru etylenu i octanu winylu z dodatkiem środków porotwórczych. Opracowany materiał został zgłoszony pod nazwą Impactex w 2005 r. do Urzędu Patentowego jako projekt wynalazczy nr P-374169. Jego skuteczność w zakresie tłumienia energii uderzenia potwierdziły rezultaty badań przeprowadzonych na stanowisku, służącym do oceny zdolności amortyzacji uderzenia ochraniaczy sportowych. Oryginalna konstrukcja stanowiska umożliwia taka ocenę przy jednoczesnym zastosowaniu dwóch metod badawczych. Została również zaproponowana nowatorska metoda oceny rozkładu siły pod ochraniaczem, podczas badań na stanowisku, wykorzystująca cienkościenne czujniki ciśnienia. Procedura badań ochraniaczy przeciwuderzeniowych przewiduje także, możliwość porównania wytypowanych wskaźników z przyjętymi w literaturze biomechanicznej wybranymi kryteriami dla określania poziomu ludzkiej tolerancji na uszkodzenie danego obszaru ciała.
As a result of research work, the fibrous material featuring 3D-structure has been developed and dedicated for impact-resistant layers of protectors applied in clothing and protective equipment for individuals practising traumatic sports. The material was gained by innovative applying eco-friendly coconut fibres, reach of lignin and binding means with co-polymer of ethylene and vinyl acetate with porogenous agent. The developed material has been submitted in 2005 under the name of IMPACTEX to the Patent Office as the invention project no. P-374169. Its efficiency on attenuating the energy of hitting was confirmed by the results of tests executed on a workstation designed for assaying the sports protectors' capability to suppress impacts. The original design of the workstation allows for such an assay with two test methods applied simultaneously. An innovative method of assaying the force distribution under the protector was also suggested, while testing on the workstation with thin-walled pressure sensors used. The testing procedure for impact-resistant protectors includes also the possibility of comparison selected indices to the selected criteria accepted by biomechanical bibliography to determine level of human toleration for injury of given area of body.
Źródło:: Techniczne Wyroby Włókiennicze; 2008, R. 16, nr 3/4, 3/4; 78-86
1230-7491
Pojawia się w:: Techniczne Wyroby Włókiennicze
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Comparative assessment of heat insulation properties of thermal resistant paints with use of infrared camera
Autorzy:: Kruczek, T.
Szczygieł, I.
Kruczek, G.
Kowalczyk, P.
Powiązania:: https://bibliotekanauki.pl/articles/114646.pdf
Data publikacji:: 2017
Wydawca:: Stowarzyszenie Inżynierów i Techników Mechaników Polskich
Tematy:: thermovision infrared measurements
thermal resistant paint
Opis:: To reduce heat losses from buildings various methods are used. One of them is applying so called “thermal resistant paints”. These paints can be put in principle on the inner but also on outer surfaces of building external walls. The aforementioned paints are put on a surface in the similar way as other paints in building construction technology and form a thin insulation layer. The acting of this paints consists in causing a noticeable temperature drop within this layer and simultaneously on the wall surface. This work presents the experimental rig, measurement procedures and selected measurement results.
Źródło:: Measurement Automation Monitoring; 2017, 63, 3; 98-101
2450-2855
Pojawia się w:: Measurement Automation Monitoring
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 6.

Tytuł:: Antibiotic resistance of bacteria and incidence of carbapenamase-coding genes blaPER and blaGES in isolates from wastewater treatment plants
Autorzy:: Jendrzejewska, Natalia
Powiązania:: https://bibliotekanauki.pl/articles/1178215.pdf
Data publikacji:: 2018
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:: antibiotics-resistant bacteria
genes
pollution
wastewater
Opis:: The increase in number of antibiotic resistant bacteria poses a serious environmental and health problem. The development of microbial resistance is intensified by the widespread use of antibiotics in medicine, veterinary, farming and aquaculture. The wastewater treatment plants receiving the wastewater from hospitals, slaughterhouses, farms, pharmaceutical industry and houses can be potential places of spreading of antibiotic resistant genes. The molecular mechanisms of the bacterial resistance, including the horizontal transfer of antibiotic resistant genes and the presence of mobile genetic elements can be responsible for the increase in antibiotic resistance during wastewater treatment. The aim of this study was to analyze the phenomenon of bacterial resistance to selected β-lactam antibiotics (ESBL) by detecting the genes that determine this resistance. The PCR method was used to analyze the occurrence of two genes: blaPER and blaGES in wastewater samples. It was revealed that the resistant/total bacteria ratio was significantly higher in the effluent compared with the influent wastewater. Genes blaPER and blaGES were isolated from several strains predominating in both aeration tank (5% and 20% respectively) and effluent wastewater (15% and 12% respectively).
Źródło:: World Scientific News; 2018, 93; 30-39
2392-2192
Pojawia się w:: World Scientific News
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 7.

Tytuł:: Analyses of the genes involved in disease development to construct disease-resistant plants by genetic engineering
Autorzy:: Tsuyumu, S.
Hirata, H.
Powiązania:: https://bibliotekanauki.pl/articles/385202.pdf
Data publikacji:: 2009
Wydawca:: Sieć Badawcza Łukasiewicz - Przemysłowy Instytut Automatyki i Pomiarów
Tematy:: genes
analyses
disease-resistant
genetic engineering
Opis:: Many genes responsible for the disease development were identified from transposon-tagging, micro-array, and proteomics analyses. Here, we introduce especially the genes required for the initiation of pathogenic life cycle, the suppression of otherwise induction of resistance responses, massive production of virulence factors in plant pathogenic bacteria and an unique plant gene responsible for the development of canker symptom. From these findings we came to raise some new strategies to construct disease-resistant plants by genetic engineering.
Źródło:: Journal of Automation Mobile Robotics and Intelligent Systems; 2009, 3, 4; 84-86
1897-8649
2080-2145
Pojawia się w:: Journal of Automation Mobile Robotics and Intelligent Systems
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 8.

Tytuł:: Acinetobacter Baumannii Nosocomial Infections
Autorzy:: Sieniawski, Karol
Kaczka, Krzysztof
Rucińska, Monika
Gagis, Ludmiła
Pomorski, Lech
Powiązania:: https://bibliotekanauki.pl/articles/1396395.pdf
Data publikacji:: 2013-09-01
Wydawca:: Index Copernicus International
Tematy:: Acinetobacter baumannii
nosocomial infections
multidrug-resistant
Opis:: Nosocomial infections caused by strains Acinetobacter baumannii strands are a growing clinical problem. The occurrence of multidrug-resistant strands is observed and that limits the ways of therapy considerably. The aim of the study was to determine the rate of infection and susceptibility spectrum of the species Acinetobacter baumannii isolated from patients treated at Maria Skłodowska-Curie Memorial Hospital in Zgierz with particular emphasis on surgical wards. Materials and methods. The material consisted of Acinetobacter baumannii isolates were obtained from samples of materials from patients treated at Maria Skłodowska-Curie Memorial Hospital in Zgierz from January to December 2011. Isolated bacterial strains were cultured at microbiological substrates. Isolates were identified to species using the VITEK 2 GN card (bioMérieux) and Vitek 2 automated system (bioMérieux). Susceptibility towards antibiotics of particular strains was determined by the means of AST NO 93 card. In the case of resistance towards carbapenem, the MIC was marked by E-test with Mueller Hinton substrate. The occurrence of MBL was verified by the means of disc system with Mueller Hinton substrate. Results. We have shown that total number of Acinetobacter baumannii infections at hospital was 140 (10,31% of total results of cultures). Percentage of Acinetobacter baumannii infections at wards: Intensive Care Unit 48%, Surgical Departments 20%, Internal Diseases Department 16%, Neurology 13%, other wards - 3%. The susceptibility percentage of Acinetobacter Baumannii against antibiotics: colistin 90%, imipenem 64%, meropenem 43%, ampicillin-sulbactam 28%, amikacin 27%, gentamicin 24%, cefepime 9%, ceftazidime 7%, ciprofloxacin 7% Conclusions. Acinetobacter baumannii infections are a significant proportion of nosocomial infections. Most relate to surgical wards and ICUs. Acinetobacter baumannii is resistant against most antibiotics. The highest percentage of sensitivity demonstrated for colistin and carbapenems
Źródło:: Polish Journal of Surgery; 2013, 85, 9; 483-490
0032-373X
2299-2847
Pojawia się w:: Polish Journal of Surgery
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 9.

Tytuł:: Past, Present & Future of Thermally Stable Explosives
Autorzy:: Agrawal, J. P.
Powiązania:: https://bibliotekanauki.pl/articles/358166.pdf
Data publikacji:: 2012
Wydawca:: Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego
Tematy:: explosives
thermally stable explosives
heat-resistant explosives
Opis:: Explosives with improved high temperature properties are usually referred to as 'thermally stable explosives' or heat-resistant explosives. They are safer, more reliable and more stable at elevated temperatures and find applications in modern Ordnance, Space and Nuclear applications. This paper discusses general approaches for the synthesis of thermally stable explosives, their properties and specific applications. This paper also gives a comparative account of the properties of some of the most thermally stable explosives reported so far. Based on their ease of synthesis, properties (mainly stability at elevated temperatures and insensitivity to impact, friction and percussion) and cost, TATB is considered as a benchmark, thermally stable explosive which is discussed in detail. Furthermore, this review also describes the synthesis and properties of BTDAONAB which does not melt below 550 °C and is considered a better thermally stable explosive than TATB. Finally, a new line of research in this field in the years to come is also highlighted.
Źródło:: Central European Journal of Energetic Materials; 2012, 9, 3; 273-290
1733-7178
Pojawia się w:: Central European Journal of Energetic Materials
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 10.

Tytuł:: Degradation of the gas turbine blade coating and its influence on the microstructure state of the superalloy
Autorzy:: Błachnio, J.
Kułaszka, A.
Zasada, D.
Powiązania:: https://bibliotekanauki.pl/articles/244112.pdf
Data publikacji:: 2015
Wydawca:: Instytut Techniczny Wojsk Lotniczych
Tematy:: turbine
blade
heat-resistant coating
technical condition
Opis:: The technical condition of the blades has a critical influence on the reliability and life span of a gas turbine and an engine into which it is built in. The main causes of blade damage are overheating, creeping, thermal fatigue, high temperature corrosion, etc. It is often caused by adverse operational conditions or manufacturing defect, e.g. using insufficiently durable types of heat-resistant protective coatings or applied in an improper manner on the blade material. Reaction of coatings and blade material to mechanical and thermal loads depends mainly on the operating temperature of the turbine. Selection of a protective coating and material to manufacture a blade with an assumed strength must take into account its mechanical and thermal properties at maximum aerofoil temperature. The article presents characteristic forms of operational damages to the gas turbine blades of a turbojet aero engine. Distinguished were operational factors and their influence on the technical condition of coatings during the engine operation period. An influence of excess exhaust gas temperature on the condition of the heat-resistant blade layer was shown. Shown were also results of morphology tests of coating degradation types. Results of micro-structure tests of the blade superalloy after damage to the heat-resistant coating were also presented.
Źródło:: Journal of KONES; 2015, 22, 2; 17-24
1231-4005
2354-0133
Pojawia się w:: Journal of KONES
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 11.

Tytuł:: A Comparism of the Response of Some Pearl Millest (Pennisetum glaucum (L.) R. BR) Hybrids and Their Parents to Downy Mildew (Sclerospora graminicola) Infestation in Bakura and Zaria (North-western Nigeria)
Autorzy:: Maryam, Ati H.
Angarawai, I. I.
Powiązania:: https://bibliotekanauki.pl/articles/1178552.pdf
Data publikacji:: 2017
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:: downy mildew
hybrids
obligate biotrophs
resistant
tolerance
Opis:: Downy mildew (Sclerospora graminicola (Sacc) Schroet.) of pearl millet [Pennisetum glaucum (L.) R.Br.] is a devastating disease that has greatly led to grain yield loss in Nigeria. A field experiment was carried out in 2010 at Bakura (Zamfara State) and Zaria (Kaduna State) in North West Nigeria. The objective of this paper was to evaluate downy mildew resistance in some pearl millet using Complete Randomized Block Design. Four resistant male varieties (PEO5532, SOSATC88, P1449 and DMR15) and four susceptible female varieties (BDP1, MOP1, LCIC9702 and PEO5984 were used in this study. The resistant varieties were crossed with the susceptible varieties using North Carolina design 11 for the mating to form sixteen (F1) hybrids. The F1 hybrids were further evaluated along with their parents for downy mildew resistance, grain yield and other agronomic traits (such as: Plant height, panicle height, number of tillers per plant, panicle diameter and number panicles per plot). The resistant male parents were found to be susceptible while none of the hybrids was resistant to downy mildew. However, the degree of incidence and severity of downy mildew disease defer in the two locations. The hybrids exhibited tolerance to downy mildew disease and their yields were higher than their parents. The analysis of variance (one tale ANOVA or which one?) showed highly significant difference among parents and hybrids for all agronomic characters except disease severity and number of tillers per plant. Location × genotype interaction effects were only significant for grain yield and number of panicles per plot.
Źródło:: World Scientific News; 2017, 70, 2; 252-264
2392-2192
Pojawia się w:: World Scientific News
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 12.

Tytuł:: Occurrence of high-level aminoglycoside resistance (HLAR) among Enterococcus species strains
Autorzy:: Sieńko, A.
Wieczorek, P.
Wieczorek, A.
Sacha, P.
Majewski, P.
Ojdana, D.
Michalska, A.
Tryniszewska, E.
Powiązania:: https://bibliotekanauki.pl/articles/1916469.pdf
Data publikacji:: 2014
Wydawca:: Uniwersytet Medyczny w Białymstoku
Tematy:: enterococcus
aminoglycoside resistance
vancomycin-resistant
enterococcus (VRE)
Opis:: Purpose: Today, Enterococcus species are one of the most frequent etiological agents in nosocomial infections. The aim of this study was to determine the susceptibility to antibiotics and the prevalence of high-level aminoglycoside resistance (HLAR) among Enterococcus strains. Materials and methods: The susceptibility of 85 isolates of Enterococcus (47 E. faecalis and 38 E. faecium) was determined using the disk diffusion method. The results were interpreted according to European Committee on Antimicrobial Suscepti-bility Testing (EUCAST) guidelines. PASW Statistics 17.0 was used for statistical analysis. Results: E. faecalis strains showed the highest susceptibility to ampicillin, tigecycline, vanco-mycin, imipenem, and linezolid and E. faecium to linezolid, tigecycline, and quinupristin/dalfopristin. Among all tested strains, high-level gentamicin resistance (HLGR) was found in 4% of E. faecalis and 8% of E. faecium strains, high-level strepto-mycin resistance (HLSR) in 45% and 42%, and HLAR in 50% and 32% of strains, respectively. HLGR was detected only in vancomycin-resistant Enterococcus (VRE)− strains (12%), while HLSR in 76.9% of VRE+ and 24% of VRE− strains, and HLAR in 23.1% of VRE+ and 64% of VRE− strains. The tested strains were also divided into two groups: HLSR+ and HLAR+. In both groups, statistically significant susceptibility differences (p<0.05) were found for ampicillin, imipenem and trimethoprim/sulfamethoxazole. The most frequent antibiotic resistance profile among E. faecalis strains was SR (resistance phenotype to strepto-mycin), and among E. faecium, AMPR, IMPR, CNR, SR, SXTR (ampicillin, imipenem, gentamicin, streptomycin, trimethoprim/sulfamethoxazole). Conclusions: This study showed the slowly increasing prevalence of HLAR and resistance to newer antibiotics (linezolid and tigecycline) among Enterococcus strains. It is necessary to search for new directions in the treatment of enterococcal infections.
Źródło:: Progress in Health Sciences; 2014, 4, 1; 179-187
2083-1617
Pojawia się w:: Progress in Health Sciences
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 13.

Tytuł:: Apalutamide in the treatment of a patient with non-metastatic castration-resistant prostate cancer
Autorzy:: Dziura, Robert
Powiązania:: https://bibliotekanauki.pl/articles/22676763.pdf
Data publikacji:: 2023-03-31
Wydawca:: Medical Education
Tematy:: prostate cancer
castration-resistant
androgen receptor inhibitor
Opis:: The treatment of patients with prostate cancer, who do not qualify for the radical therapy is based on the use of surgical or pharmacological castration methods. The effectiveness of the so-called androgen deprivation tends to decrease over time. Even in the absence of distant metastases on imaging studies, the resistance for the hormonal castration may be developed. At this moment, the use of new generation androgen receptor inhibitors may reduce the risk of metastases or death. The paper presents a case report of a patient with prostate cancer without distant metastases who started therapy with apalutamide at the moment of developing re-sistance to the pharmacological castration.
Źródło:: OncoReview; 2023, 13, 1; 20-23
2450-6125
Pojawia się w:: OncoReview
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 14.

Tytuł:: Apalutamide as a new option for postponing metastatic disease in hormone -resistant patients with biochemical recurrence in prostate cancer
Autorzy:: Dąbek, Bartosz
Powiązania:: https://bibliotekanauki.pl/articles/22676825.pdf
Data publikacji:: 2023-04-04
Wydawca:: Medical Education
Tematy:: non-metastatic castration-resistant prostate cancer
apalutamide
Opis:: Treatment of non-metastatic castration-resistant prostate cancer is a radically new option for cancer patients. Novel anti-hormonal therapy not only improves metastasis free survival but overall survival times and positively impacts quality of life. This case shows how apalutamide lowered tPSA level and postponed metastatic disease.
Źródło:: OncoReview; 2023, 13, 1; 24-26
2450-6125
Pojawia się w:: OncoReview
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 15.

Tytuł:: Pollution in Shatt Al-Arab River near Hospital Wastewater Disposal – Detection of Pharmaceutical Compounds, Isolation and Identification of Drug-Resistant Bacteria
Autorzy:: Alsaad, Noor Kadhim
Almansoory, Asia Fadhile
Al-Baldawi, Israa Abdulwahab
Powiązania:: https://bibliotekanauki.pl/articles/2202283.pdf
Data publikacji:: 2022
Wydawca:: Polskie Towarzystwo Inżynierii Ekologicznej
Tematy:: resistant bacteria
well diffusion
river
pharmaceutical
micropollutants
Opis:: Pharmaceutical compounds have been introduced into the aquatic ecosystems in multiple ways and sources, which negatively affects the health of the environment and humans. The river near the hospital sewage disposal is host environment for drug-resistant bacteria (DRB). In this context, the aim of the research was to detect the presence of pharmaceuticals in hospital wastewater, after treatment, at river point followed by isolation of bacteria and test for resistant pharmaceutical compound. Fifteen species of bacteria isolated by angiogenic methods were identified and tested using the well diffusion test to determine the resistance of selected bacteria to ibuprofen by survival assessment. This study showed that the ibuprofen detected by GC-mass was available in all selected points at a concentration of 3 to 120 mg/L. Lecuco. mesen.cremris and Koc.rosea have a high ability to break down the ibuprofen compound. Thus, the bacteria isolated from hospital wastewater can biologically degrade ibuprofen.
Źródło:: Journal of Ecological Engineering; 2022, 23, 12; 29--36
2299-8993
Pojawia się w:: Journal of Ecological Engineering
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 16.

Tytuł:: Comparative analysis of welded and adhesive joints strength made of acid-resistant stainless steel sheets
Autorzy:: Rudawska, A.
Pawlak, P.
Miturska, I.
Stančeková, D.
Chyra, M.
Powiązania:: https://bibliotekanauki.pl/articles/102070.pdf
Data publikacji:: 2017
Wydawca:: Stowarzyszenie Inżynierów i Techników Mechaników Polskich
Tematy:: adhesive joints
welded joints
strength
acid resistant steel
Opis:: The article presents the selected results of strength tests on the effectiveness of bonding high-alloy steel 1.4310. Sheet steel is one of the materials that are difficult to activate energy. Effective joining of it is difficult, requires selection of the appropriate bonding technology. The paper focuses on the comparative tests of shear strength of one-single lap welded and bonded joints. The welding process was performed on 3 groups of samples TIG welding and argon, where the variable value of the welding process was current: 60A, 70A, 80A. The adhesion process was performed in 6 groups of samples which differed in the method of surface preparation and the type of the adhesive. Adhesive joints were made by using adhesive of epoxy resin and a hardener: Epidian 61/TFF at a mass ratio of 100:22 and Epidian 61/IDA at a mass ratio of 100:40. As a way of surface preparation applied 3 different, but simplified and environmentally friendly methods of surface preparation: degreasing with using cleaner Loctite 7061, abrasive machining with P320 and degreasing and grinding with abrasive T800 and degreasing were used. Make joints and curing the adhesive joints were carried out at ambient temperature. Analyzed the joints were tested destructive – which set out the shear strength, in accordance with DIN EN 1465 on the testing machine Zwick / Roell Z150. Based on the results of the research it was found that better results were obtained for the maximum welded joints, but this result was similar to the maximum value of the strength of the adhesive bond.
Źródło:: Advances in Science and Technology. Research Journal; 2017, 11, 4; 97-102
2299-8624
Pojawia się w:: Advances in Science and Technology. Research Journal
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 17.

Tytuł:: Cardiovascular complications during the treatment of castration-resistant prostate cancer with the use of modern antiandrogens: abiraterone acetate and enzalutamide
Autorzy:: Grabysa, Radosław
Chmielewska, Agnieszka
Powiązania:: https://bibliotekanauki.pl/articles/2047222.pdf
Data publikacji:: 2021-09-13
Wydawca:: Medical Education
Tematy:: abiraterone acetate
enzalutamide
castration resistant prostate cancer
cardiovascular
Opis:: Modern antiandrogens: abiraterone acetate (inhibitor of CYP17 cytochrome) and enzalutamide (irreversible inhibitor of androgen receptor) are the drugs that are increasingly often administered in treatment of castration-resistant prostate cancer. Despite their clinical efficacy, especially in terms of prolonged survival and improved quality of life of patients, they pose of problem for a practicing oncologist such as possible cardiovascular complications (particularly arterial hypertension), which may lead to the cessation of this form of therapy. This article provides a brief overview of the mechanisms responsible for the above complications, including practical recommendations in the event such complications arise. A simple scheme of action for control of cardiovascular risk factors has been presented, which can improve the prognosis in this population of patients.
Źródło:: OncoReview; 2021, 11, 3; 61-67
2450-6125
Pojawia się w:: OncoReview
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 18.

Tytuł:: Multiaxial force platform with disturbance compensation for machine tools
Autorzy:: Palalic, Marijana
Möhring, Hans-Christian
Maier, Walther
de Mendoza, Adrian Gonzalez
Riemeier, Friedrich
Powiązania:: https://bibliotekanauki.pl/articles/99882.pdf
Data publikacji:: 2020
Wydawca:: Wrocławska Rada Federacji Stowarzyszeń Naukowo-Technicznych
Tematy:: force determination platform
disturbance-resistant
FEA
multibody system
Opis:: As part of a cooperation project between the Institute for Machine Tools, Stuttgart, Germany, and EMO Systems/Nuton GmbH, Berlin, Germany, a prototype of a multiaxial force platform with disturbance compensation for the measurement of the cutting forces in machine tools was developed. Commercially available products based on piezoelectric technology are subject to a degree of measurement uncertainty and therefore characterized by various disturbances. Interpreting measurement data of the commercially available products is complex, time-consuming and prone to errors. This paper describes the mechanical design and the simulation of the multiaxial force measuring system with the finite element method (FEM) as well as the conceptual development of a reduced model for a multibody simulation with the purpose of implementing a compensation algorithm. The measurement uncertainty was reduced by using appropriate hardware and software for the compensation of the various disturbances so that the application of the force platform would also be possible in the industrial application for the process diagnosis, the control and the regulation in machine tools. Systems based on strain gauge technology have some advantages in the field of zero-point stability and also provide a less expensive solution. For the disturbance compensation, an additional force and torque sensor system with eight channels was used for the detection of the platform displacement and inclination. With the help of appropriate algorithms for the disturbance compensation and their integration in the evaluation software, the disturbances could be reduced to a minimum.
Źródło:: Journal of Machine Engineering; 2020, 20, 3; 5-16
1895-7595
2391-8071
Pojawia się w:: Journal of Machine Engineering
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 19.

Tytuł:: Ochraniacze przeciwuderzeniowe w sporcie - moda i konieczność
Impact-resistant protectors at sports - fashion and necessity
Autorzy:: Maklewska, E.
Powiązania:: https://bibliotekanauki.pl/articles/237926.pdf
Data publikacji:: 2008
Wydawca:: Instytut Technologii Bezpieczeństwa Moratex
Tematy:: ochraniacze przeciwuderzeniowe
sport
urazy
impact-resistant protectors
injuries
Źródło:: Techniczne Wyroby Włókiennicze; 2008, R. 16, nr 1/2, 1/2; 8-14
1230-7491
Pojawia się w:: Techniczne Wyroby Włókiennicze
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 20.

Tytuł:: Multi Drug Resistant Tuberculosis
Autorzy:: Zacharia, Balaji
Roy, Antony
Powiązania:: https://bibliotekanauki.pl/articles/454987.pdf
Data publikacji:: 2019
Wydawca:: Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:: BACTEC
MDRTB
multi drug resistant tuberculosis Mycobacterium
tuberculosis
Opis:: Introduction. Tuberculosis is one of the oldest infections known to mankind. Of all infectious diseases, tuberculosis causes the most fatalities of any infection. The incidence of tuberculosis on the rise due to the increased prevalence of HIV infection. The incidence of drug resistance strains of mycobacterium is also on the rise. When the mycobacterium is resistant to both INH and rifampicin it is called multi drug resistant tuberculosis. There is a primary and an acquired type of drug resistance. Multidrug resistant tuberculosis is a not only a problem for the patient but also for society at large. The treatment of multidrug resistant tuberculosis requires an entirely different approach. Aim. In this review, we are going to describe the etiopathogenesis, diagnosis, investigations and treatment of multi drug resistant tuberculosis. Material and methods. Analysis of the current literature. Results. Genetic factors, previous treatment, and other factors predisposes the onset of drug resistance. By early detection and prevention of spread of drug resistant strains we can prevent the spread of resistant strains. Conclusion. Drug resistance in tuberculosis is a very complex and dangerous problem. We have to prevent the development and spread of MDRTB. Good quality drugs should be used and made available to all sections of the population. Enhancing the National tuberculosis programs is the best way to attain an effective way to control this menace.
Źródło:: European Journal of Clinical and Experimental Medicine; 2019, 3; 262-269
2544-2406
2544-1361
Pojawia się w:: European Journal of Clinical and Experimental Medicine
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 21.

Tytuł:: The Potential of Mercury-Resistant Bacteria Isolated from Small-Scale Gold Mine Tailings for Accumulation of Mercury
Autorzy:: Chasanah, U.
Nuraini, Y.
Handayanto, E.
Powiązania:: https://bibliotekanauki.pl/articles/124273.pdf
Data publikacji:: 2018
Wydawca:: Polskie Towarzystwo Inżynierii Ekologicznej
Tematy:: mercury-resistant bacteria
small-scale gold mine tailing
Opis:: In certain small-gold mining activities in West Lombok, Indonesia, the tailings containing mercury are discharged to agricultural lands, reducing their productivity. One of the efforts to restore the land is by bioremediation of mercury, using mercury-resistant microbes. This study was aimed to isolate the mercury-resistant bacteria from small-scale gold mine tailings containing mercury, and to test their capability in accumulating mercury. Bacterial isolation and identification were conducted from nutrient broth supplemented with 5 ppm HgCl₂. The isolated bacteria were tested for mercury accumulation in the nutrient broth containing 10, 20 and 30 ppm Hg for 24 hours, and in small-scale gold mine tailing containing 41.37 ppm Hg for 2 weeks. The results showed that there were four pure isolates of mercury-resistant bacteria which were identified as Brevundimonas vesicularis, Nitrococcus mobilis, Fusobacterium aquatile and Fusobacterium necrogenes. The highest Hg accumulation from nutrient broth liquid media containing 10, 20 and 30 ppm Hg was observed for Brevundimonas vesicularis. The mercury accumulation efficiency of the four bacteria applied to small-scale gold mine tailing containing mercury was in the order of Fusobacterium aquatile (76.1%) > Brevundimonas vesicularis (75.6%) > Fusobacterium necrogenes (74.4%) > Nitrococcus mobilis (74.2%). On the basis of the Hg accumulation efficiency of more than 75%, Fusobacterium aquatile and Brevundimonas vesicularis are prospective for bioremediation of mercury-contaminated soils.
Źródło:: Journal of Ecological Engineering; 2018, 19, 2; 236-245
2299-8993
Pojawia się w:: Journal of Ecological Engineering
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 22.

Tytuł:: Analysis of Acinetobacter baumannii resistance patterns in patients with chronic obstructive pulmonary disease (COPD) in terms of choice of effective empiric antibiotic therapy
Autorzy:: Grochowalska, Aneta
Kozioł-Montewka, Maria
Sobieszczańska, Anna
Powiązania:: https://bibliotekanauki.pl/articles/989765.pdf
Data publikacji:: 2017
Wydawca:: Instytut Medycyny Wsi
Tematy:: copd
antibiotics
acinetobacter baumannii
multidrug-resistant strains
co-infection
Opis:: Introduction. Multi-resistant Acinetobacter baumannii isolated from patients has become one of the most hazardous pathogens in health care settings. The aim of the study was to analyze pneumonia caused by Acinetobacter baumannii in patients hospitalized because of exacerbation of chronic obstructive pulmonary diseases (COPD), who were admitted to the Pulmonology Ward of the Masovian Specialistic Hospital in Radom (MSS). The incidence and drug sensitivity of these non-fermenting rods were evaluated, and compliance with antimicrobial procedure with the algorithm of the guidelines in applicable recommendations, was estimated. This should result in determining the local patterns of resistance and verifying therapeutic procedures in accordance with the assumptions of hospital antibiotic policy. In addition, the study examined the effectiveness of empiric and targeted therapy according to the clinical condition of the patient, and the eradication of A. baumannii, in comparison with the aggravating factors of the patient. Materials and Method. The retrospective study included 90 patients with exacerbation of COPD whose etiological factor of infection was A. baumannii, hospitalized in the Department of Pulmonology (MSS) in 2012–2016. Results. Studies were conducted on 90 patients with COPD exacerbation from which A. baumannii was isolated. Co-infections with other bacterial species among 41 patients were additionally noted. The majority of A. baumannii strains showed a high resistance (90%) to fluoroquinolones, ceftazidime, piperacillin/tazobactam. For strains causing a co-infection, drug resistance was successively 44–56%, 44%, 44%. All of patients received empirical therapy. The most commonly used drug was amoxicillin with a clavulanic acid, often combined with fluoroquinolone. This type of therapy was effective among 10% of patients. The mortality in this group was determined at 29%. Among 79% of patients with COPD, a targeted therapy was performed which proved to be effective in 58% of treated cases by susceptibility testing. The highest efficacy was observer after the use of colistin and carbapenems. Conclusion. In the performed study, the infections caused by multi-resistant Acinetobacter baumannii, were observed in COPD, which should be taken into consideration in choosing empirical antibiotic therapy. Simultaneously, the local resistance patterns of multi-drug-resistant (MDR) Gram-negative strains co-infecting COPD should be considered in empirical treatment. Moreover, both additional clinical complication and co-infections contribute to a more severe course of diseases. In this study, the mortality percent exceeded 29%.
Źródło:: Annals of Agricultural and Environmental Medicine; 2017, 24, 2
1232-1966
Pojawia się w:: Annals of Agricultural and Environmental Medicine
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 23.

Tytuł:: Image encryption based on Chebyshev chaotic map and S8 S-boxes
Autorzy:: Hussain, Iqtadar
Anees, Amir
Alkhaldi, Ali Hussain
Aslam, Muhammad
Siddiqui, Nasir
Ahmed, Rehan
Powiązania:: https://bibliotekanauki.pl/articles/173918.pdf
Data publikacji:: 2019
Wydawca:: Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:: image encryption
chaos
noise-resistant
statistical analysis
key sensitivity
Opis:: The encryption of image data is artful as compare to others due to some special characteristics such as entropy, contrast, the correlation between the pixels, intensity, and homogeneity. During encryption process, it is conventionally not easy to manage these characteristics with non-chaotic cryptosystems. Therefore for the sake of strong encryption algorithms, in last decades many cryptographers have presented invulnerable schemes for image encryption based on the chaotic maps. This manuscript aims to propose a strong encryption scheme based on a symmetric group of permutation advanced encryption standard (AES) substitution boxes and modified Chebyshev map. Principally, the secret key depends upon the parameters of Chebyshev map to create confusion in the main image and is encrypted by the scheme made from the S8 AES S-boxes and chaotic map. By this procedure, one can obtain an encrypted image that is entirely twisted. The results of analyses showed that the presented image encryption is strong and invulnerable.
Źródło:: Optica Applicata; 2019, 49, 2; 317-330
0078-5466
1899-7015
Pojawia się w:: Optica Applicata
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 24.

Tytuł:: Apalutamide in the treatment of non-metastatic castration-resistant prostate cancer in an elderly patient with multiple comorbidities
Autorzy:: Liśkiewicz, Katarzyna
Powiązania:: https://bibliotekanauki.pl/articles/22676727.pdf
Data publikacji:: 2023-03-30
Wydawca:: Medical Education
Tematy:: non-metastatic castration-resistant prostatic cancer
androgen receptor
apalutamide
Opis:: Prostate cancer has been the most common malignant tumor in men in Poland since 2016 and is the second cause of death in this group of patients. The basic method of treatment in patients with advanced prostate cancer is androgen deprivation therapy, however, over time, the tumor evolves into a castration-resistant form, which poses a significant threat to the patient's life. This article presents a case of an elderly patient with internal diseases, who in the castration-resistant stage, was treated with a new generation androgen receptor blocker – apalutamide – in the first line of systemic treatment.
Źródło:: OncoReview; 2023, 13, 1; 9-12
2450-6125
Pojawia się w:: OncoReview
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 25.

Tytuł:: Effects of an enzyme agent containing mutanase and dextranase for treatment of biofilms in bacteria- and yeast-infected canine otitis externa
Autorzy:: Fujimura, M.
Powiązania:: https://bibliotekanauki.pl/articles/16539344.pdf
Data publikacji:: 2022
Wydawca:: Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:: biofilm
canine otitis externa
enzyme agents
drug-resistant bacteria
Opis:: The purpose of this study was to evaluate in detail both the in vivo and in vitro efficacy of the enzyme agents, ZYMOX® Plus Otic (ZYMOX-P), in the treatment of canine otitis externa (OE). Eight dogs with a diagnosis of non-seasonal severe chronic OE were recruited for the study. ZYMOX-P was administered for 2-4 weeks. The Otitis Index Score (OTIS3) and bacteria or yeast colony growth were measured. Also, minimum biofilm (BF) formation inhibition concentration (MBIC) and BF bactericidal concentration (BBC) were measured in vitro. OTIS3 showed a statistically significant reduction after treatment (88.2%, p<0.001; pre-treatment = 11.0 ± 0.9; post-treatment = 1.3 ± 0.4, mean ± SEM). The individual OTIS scores, erythema, edema, erosions/ ulcerations, exudate and pruritus showed significant reduction (85.7%, 95.7%, 83.3%, 80.0%, and 89.3%, respectively). Microscopic examination revealed the presence of BF exopolysaccharide in all 8 ear samples when stained with alcian blue. Seven of the 8 dogs (87.5%) showed a reduction in colony growth. ZYMOX-P was effective at 34-fold and 16-fold dilutions on MBIC and BBC, respectively. These findings indicate that ZYMOX-P has efficacy against BF-related infection and is beneficial when used for the management of canine OE.
Źródło:: Polish Journal of Veterinary Sciences; 2022, 25, 3; 383-389
1505-1773
Pojawia się w:: Polish Journal of Veterinary Sciences
Dostawca treści:: Biblioteka Nauki

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