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    Wyświetlanie 1-55 z 55
    Tytuł:
    Narzędzie wspomagające projektowanie usług design-thinking
    A tool supporting service design based on design-thinking
    Autorzy:
    Studzińska, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/322452.pdf
    Data publikacji:
    2017
    Wydawca:
    Politechnika Śląska. Wydawnictwo Politechniki Śląskiej
    Tematy:
    design-thinking
    design
    projektowanie usług
    modele projektowania usług
    doskonalenie
    podnoszenie jakości
    service design
    service design models
    quality improvement
    Opis:
    W świetle mnogości dostępnych modeli planowania usług design-thinking, organizacje stają przed dylematem wyboru. W literaturze przedmiotu brakuje jednoznacznych wskazań co do decyzji o doborze najbardziej odpowiedniego modelu, szczególnie w kontekście różnych uwarunkowań dla poszczególnych sektorów rynku. Stworzona baza determinant jakości w formie dwuetapowego narzędzia pozwoli organizacjom uporządkować wiedzę, co w efekcie doprowadzi do określenia globalnego celu, który ułatwi wykorzystanie aplikacji koncepcji design-thinking do planowania usług.
    In light of the multitude of design-thinking service planning models available, organizations face the dilemma of choice. The literature on the subject lacks clear indications as to the decision to select the most suitable model, especially in the context of different conditions of market sectors. The database of quality determinants in a form of a two-stage-tool will allow organizations to systemize their knowledge which will ultimately enable them to determine the global goal, thus simplifying the application of design-thinking for service design.
    Źródło:
    Zeszyty Naukowe. Organizacja i Zarządzanie / Politechnika Śląska; 2017, 113; 469-479
    1641-3466
    Pojawia się w:
    Zeszyty Naukowe. Organizacja i Zarządzanie / Politechnika Śląska
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Alcohol consumption patterns among young people from rural areas of Lublin Province
    Autorzy:
    Makara-Studzinska, M
    Urbanska, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/50250.pdf
    Data publikacji:
    2007
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    alcohol initiation
    young people
    alcohol consumption
    Lublin region
    Polska
    rural area
    drinking
    Europe
    social problem
    Opis:
    The article aims at the increasing of knowledge among young people coming from the country, studying at various types of schools – from the aspect of frequency of their drinking, age of alcohol initiation and preferences towards alcoholic drinks. We examined 5,000 young people from rural areas in Lublin province between the ears 2002- 2004. A screening questionnaire that included AUDIT test (the Alcohol Use Disorders Identifi cation Test) was used. The AUDIT was developed by the WHO to identify hazardous and harmful alcohol consumption. The results showed that both frequency and alcohol initiation age were related to type of school and sex of young people. We found that young people from rural areas of Lublin province do not differ from all-Polish trends in relation to these patterns. Some changes in the alcohol consumption model in Polish villagers were noted. Young people in the country clearly prefer beer drinks. Restrictions regarding alcohol sales to young people are not complied with. In almost half of the group we found alcoholism in families. Our fi ndings show that antialcoholic prophylaxis should be initiated in the fi rst years of childrens’ education. Preventive programmes should be based not only on school, but also on the family.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2007, 14, 1
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Prawo pacjenta z uszkodzeniem słuchu do informacji medycznej a kwestia świadomej zgody na podejmowanie interwencji medycznych
    The right of a patient with hearing impairment to medical information and the issue of informed consent for undertaking medical interventions
    Autorzy:
    Makara-Studzinska, M.
    Kowalska, A.J.
    Powiązania:
    https://bibliotekanauki.pl/articles/4054.pdf
    Data publikacji:
    2011
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Medycyna Ogólna i Nauki o Zdrowiu; 2011, 17(46), 3
    2083-4543
    Pojawia się w:
    Medycyna Ogólna i Nauki o Zdrowiu
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Analysis of the impact of education level on the sense of coherence and opinion concerning carrying out preventive vaccination
    Autorzy:
    Makara-Studzinska, M.
    Sidor, K.
    Kalinowski, P.
    Powiązania:
    https://bibliotekanauki.pl/articles/3235.pdf
    Data publikacji:
    2015
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    human disease
    education level
    coherence
    opinion
    preventive strategy
    vaccination
    infectious disease
    Opis:
    Introduction. Nowadays, preventive vaccination is still the most effective method of countering and combating infectious diseases. Objective. The objective of the present study was to take into consideration the education of the respondents while learning about their views and attitudes towards both compulsory and recommended preventive vaccination in Poland. Materials and methods. An interview survey was conducted among 370 respondents – students and young parents residing in the Lublin province of eastern Poland. The research tools were an authors’ questionnaire and a Life Orientation Questionnaire (SOS-29). Results. The majority of respondents with secondary education (77.40%), undergraduate education (63.71%), and graduate education (55.07%) stated that sometimes preventive vaccination may have life-threatening consequences. A very small percentage of both groups of respondents with secondary and undergraduate education expressed the opinion that such situations often happen (1.69% vs. 1.61%), but this opinion was not shared by any of the respondents with graduate education. Analyzing the dependency between the sense of coherence and one’s level of education, a significant difference between the respondents with secondary education and undergraduate education was observed. Although differences between respondents with graduate education and respondents with undergraduate education existed, they were not very significant. Conclusions. The educational background of the respondents has an impact on their opinions on preventive vaccination. The great majority of respondents believed that vaccination is necessary in order to avoid many dangerous diseases. Respondents with graduate education evaluated preventive vaccination in a positive or a very positive way. The subjects differed in their global sense of coherence together with its components. The general sense of coherence stood at an average level, with the mean of 129.02 points. The highest results were obtained by the respondents in the area of resourcefulness, which is a belief that they had at their disposal remedial resources, including preventive vaccination.
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2015, 09, 1
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Stress and occupational burnout in a population of Polish doctors – Organizational-professional and non-professional-social predictors
    Autorzy:
    Makara-Studzińska, M.
    Wontorczyk, A.
    Izydorczyk, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/2086043.pdf
    Data publikacji:
    2020
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    burnout syndrome
    doctors
    stress at work
    burnout
    non-professional-social predictors
    organizational-professional predictors
    Opis:
    Introduction and objective. Numerous studies have found that doctors are exposed to stress and burnout at work. In consequence, these processes lead to a decrease in the quality of life. The study aimed to determine whether professional burnout, understood as a cognitive existential process, is related to stress at work and if any of the four dimensions of burnout are its predictor. The study also analyzed relations between organizational-professional and non-professional-social factors and burnout and stress at work. Materials and method. 318 doctors (210 women, 108 men), aged 27 – 8, participated in the study. Link Burnout Questionnaire (LBQ) was used to measure burnout, and the Perceived Stress Scale (PSS-10) to measure the variable describing the current level of stress. Results. Occupational burnout is related to stress. Two of its symptoms: exhaustion and lack of a sense of professional effectiveness, are important predictors for the sense of stress experienced by the examined group of doctors. The individuals who are in a partner relationship (but not marriage) experienced a stronger sense of non-professional effectiveness than those who were single. Being in an informal relationship is related to the level of stress and lack of a sense of professional effectiveness. The level of stress, as well as all burnout indicators, are connected with the function of a team leader and having passion. The frequency of taking leave and using social networks is related to the level of stress and burnout. Conclusions. Problems related to burnout in doctors, and therefore people professionally involved in helping and treating, must not be underestimated, as evidenced by the results of the presented study Professional burnout of doctors leads to somatic and psychological problems. Doctors suffering from occupational burnout need support and psychological assistance the same as any other professional group.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2020, 27, 3; 456-468
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The quality of life in patients with schizophrenia in community mental health service - selected factors
    Autorzy:
    Makara-Studzinska, M.
    Wolyniak, M.
    Partyka, I.
    Powiązania:
    https://bibliotekanauki.pl/articles/3162.pdf
    Data publikacji:
    2011
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    life quality
    patient
    human disease
    psychiatric disease
    schizophrenia
    health service
    socio-demographic factor
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2011, 05, 1
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Physical activity in perimenopausal women
    Autorzy:
    Makara-Studzinska, M.
    Krys-Noszczyk, K.M.
    Powiązania:
    https://bibliotekanauki.pl/articles/3677.pdf
    Data publikacji:
    2015
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    physical activity
    perimenopausal woman
    menopause
    woman
    body mass index
    Opis:
    Introduction. The menopausal age of women is characterized by a high probability of health problems related with oestrogen deficiency and reduced ovarian hormonal activity. The most significant element in the therapy of the menopausal problems is to take part in physical activity on at least a moderate level, which is sufficient to maintain health. Objective. To investigate the effect of physical activity on the severity of the symptoms of menopause and body mass index BMI, which can decisively influence menopause. Material and methods. A group of respondents consisting of 210 women aged between 45–65 who were not using hormone replacement therapy, and staying at a rehabilitation centre. The study was conducted in 2013–2014 in the provinces of Silesia, Podlasie and Malopolska. Research tools consisted of a self-designed survey questionnaire and the Menopause Rating Scale (MRS). Results. Mean BMI indicated overweight of the women and their infrequency and low level participation in physical activity. The intensity of menopausal symptoms increased with BMI, and low physical activity of the respondents decreased with age. Increase in the intensity of physical activity decreased the severity of symptoms characteristic for menopausal age. Conclusions. Physical activity can play an important role in reducing menopausal symptoms and preventing the most frequently occurring diseases of menopausal age.
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2015, 09, 1
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Occurrence of depression and anxiety disorders according to the period of abstinence in patients addicted to gambling and alcohol
    Autorzy:
    Makara-Studzinska, M.
    Pylypczuk, A.
    Urbanska, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/3135.pdf
    Data publikacji:
    2011
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    occurrence
    depression
    anxiety disorder
    abstinence period
    patient
    gambling
    alcohol
    anxiety
    human disease
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2011, 05, 1
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Evaluation of the state of health of motor vehicle operators driving under the influence of alcohol in the years 2004, 2007 and 2010 in Kielce Region
    Autorzy:
    Makara-Studzinska, M.
    Latala-Los, E.
    Los, R.
    Powiązania:
    https://bibliotekanauki.pl/articles/3158.pdf
    Data publikacji:
    2012
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2012, 06, 2
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Poziom wiedzy oraz opinie pielęgniarek na temat transplantacji organów
    Level of knowledge and opinions of nurses concerning organ transplants
    Autorzy:
    Makara-Studzinska, M.
    Kowalska, A.J.
    Jakubowska, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/3975.pdf
    Data publikacji:
    2012
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Medycyna Ogólna i Nauki o Zdrowiu; 2012, 18(47), 1
    2083-4543
    Pojawia się w:
    Medycyna Ogólna i Nauki o Zdrowiu
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Diabetes and depression: a combination of civilization and life-style diseases is more than simple problem adding - literature review
    Autorzy:
    Dziemidok, P,
    Makara-Studzinska, M.
    Jarosz, M.J.
    Powiązania:
    https://bibliotekanauki.pl/articles/52014.pdf
    Data publikacji:
    2011
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    human disease
    diabetes
    depression
    life style
    complication
    patient
    treatment
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2011, 18, 2
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Acceptance of diagnostic and therapeutic methods by married couples treated due to infertility
    Autorzy:
    Makara-Studzinska, M.
    Morylowska-Topolska, J.
    Wdowiak, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/3582.pdf
    Data publikacji:
    2010
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2010, 04, 2
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Level of magnesium in patients with depression treated with lithium – pilotage research
    Autorzy:
    Makara-Studzinska, M.
    Dabrowski, W.
    Kielczykowska, M.
    Musik, I.
    Powiązania:
    https://bibliotekanauki.pl/articles/51269.pdf
    Data publikacji:
    2013
    Wydawca:
    Instytut Medycyny Wsi
    Opis:
    Introduction. Depression is a major public health problem. Magnesium (Mg2+) is involved in many metabolic processes as an activator of over 300 different enzymes. For the last 60 years lithium (Li+) compounds have been used in psychiatry. Li+ salts are regarded as the first choice medicine in the treatment of affective disorders and are also applied as an adjuvant intensifying the therapy in drug-resistant depression patients. Objective. The objective of the study was an analysis of the relationship between the levels of magnesium, lithium, and education and place of residence of patients hospitalized due to depression. Material and methods. Patients with bipolar affective disorders undergoing lithium therapy during their stay in the Department of Psychiatry at the Medical University in Lublin were examined. Patients were divided into three groups according to education level and were also analyzed according to place of residence. Results. In the group of patients in the study, a significantly lower level of magnesium was found (p=0.02) in blood plasma of patients with secondary education level, compared to those who had elementary education. There was also a significantly higher level of magnesium (p=0.01) in blood plasma of patients who lived in urban areas, compared to rural inhabitants. No statistically significant differences were noted between lithium level in plasma, and the patients’ place of residence (p=0.34). Conclusion. Significantly higher plasma magnesium levels were observed among city than village inhabitants, there was also a relationship between type of education and magnesium level in blood plasma of the patients in the study. Further studies including larger groups of patients should be performed to enable a final conclusion.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2013, 20, 1
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Intensification of anxiety and depression, and personal resources among women during the peri-operative period
    Autorzy:
    Lewicka, M.
    Makara-Studzinska, M.
    Sulima, M.
    Wiktor, H.
    Powiązania:
    https://bibliotekanauki.pl/articles/49872.pdf
    Data publikacji:
    2014
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2014, 21, 1
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Stichorchis subtriquetrus as a common parasite of beavers indigenous to the Lublin region
    Autorzy:
    Demkowska-Kutrzepa, M.
    Studzinska, M.
    Tomczuk, K.
    Rozanski, P.
    Powiązania:
    https://bibliotekanauki.pl/articles/6658.pdf
    Data publikacji:
    2016
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    Stichorchis subtriquetrus
    Paramphistomatidae
    trematode
    parasite
    animal parasite
    beaver
    Castor fiber
    Lublin region
    Źródło:
    Annals of Parasitology; 2016, 62, Suppl.
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Do Polish doctors suffer from occupational burnout syndrome? An attempt to find an answer - pilot study
    Autorzy:
    Makara-Studzińska, M.
    Załuski, M.
    Tylec, A.
    Panasiuk, L.
    Powiązania:
    https://bibliotekanauki.pl/articles/2082055.pdf
    Data publikacji:
    2018
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    burnout syndrome
    physicians
    occupational stress
    psychological processes
    Opis:
    Introduction and objective. A nationwide survey, carried out in Poland in 2013, showed that 42% of an examined group of doctors reported occupational burnout syndrome (OBS). The phenomenon of OBS among medical personnel shows a relationship with perceived stress scale (PSS) scores. The aim of the study was to estimate the prevalence of OBS in a group of Polish doctors, and the relationship with selected risk factors and personal resources. Materials and method. A cross-sectional study using quantitative methodology was used with the application of a questionnaire method and correlation design. Questionnaires were administered to 318 doctors (42 different specialties) working in medical facilities in Poland. All participants in the study completed two standardized questionnaires: Link Burnout Questionnaire (LBQ), Perceived Stress Scale (PSS), and responded to the questions on a proprietary questionnaire. ANOVA variance analysis and analysis of regression was performed. Results. The results of the measurement of four aspects of occupational burnout: psychophysical exhaustion (PE), commitment to relationships with patients (CP), effectiveness in performed work (EW), and existential expectations (EE), were in the medium and high levels range. Every second medical doctor who participated in the research declared a high degree of occupational burnout in each of the aspects of OBS. The high level of PSS scores, the large number of duties per month, the short work experience (years of employment) and the low number of holiday leaves, were the predictors of occupational burnout in the group of doctors taking part in the study. Conclusions. The prevalence of the signs of OBS among Polish doctors is consistent with the results of research in other countries. Failures in the interventions taken to reduce stress seem to co-exist with the severity of signs of burnout.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2019, 26, 1; 191-197
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Opieka personelu medycznego oddziałów położniczych nad kobietą i noworodkiem - w ocenie pacjentek
    Care of mother and newborn provided by medical staff in maternity wards in opinions of patients
    Autorzy:
    Makara-Studzinska, M.
    Wdowiak, A.
    Podstawka, D.
    Stec, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/4257.pdf
    Data publikacji:
    2013
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Medycyna Ogólna i Nauki o Zdrowiu; 2013, 19(48), 3
    2083-4543
    Pojawia się w:
    Medycyna Ogólna i Nauki o Zdrowiu
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Experimental and Theoretical Studies of Heat Losses from the Hot Water Storage Tank
    Badania eksperymentalne i teoretyczne strat ciepła zasobnika ciepłej wody
    Autorzy:
    Dopieralska, K.
    Siuta-Olcha, A.
    Cholewa, T.
    Studzińska, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1818096.pdf
    Data publikacji:
    2016
    Wydawca:
    Politechnika Koszalińska. Wydawnictwo Uczelniane
    Tematy:
    heat loss coefficient
    hot water tank
    thermal stratification
    współczynnik strat ciepła
    zbiornik ciepłej wody
    stratyfikacja termiczna
    Opis:
    Efektywność magazynowania ciepła ma wpływ na efektywność energetyczną instalacji ciepłej wody. Do jej zwiększenia przyczynia się utrzymanie rozwarstwienia termicznego w zasobniku ciepłej wody. Zaburzenie stratyfikacji termicznej może być spowodowane między innymi stratami ciepła ze zbiornika do otoczenia. W pracy przedstawiono dynamikę zmian temperatury wody w zasobniku o pojemności 350 dm3, podczas jego wychładzania w godzinach nocnych, na podstawie przeprowadzonych pomiarów temperatury wody magazynowanej na 15 wyróżnionych poziomach. Dla zasobnika obliczono współczynniki strat ciepła dla części górnej, bocznej oraz dolnej, jak również dla całego zasobnika. Uzyskane wyniki odniesiono do wyników badań innych autorów.
    Źródło:
    Rocznik Ochrona Środowiska; 2016, Tom 18, cz. 2; 758-769
    1506-218X
    Pojawia się w:
    Rocznik Ochrona Środowiska
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Self-perception of body by women of child-bearing age
    Autorzy:
    Makara-Studzinska, M.
    Wrotna, M.
    Krys-Noszczk, K.
    Wdowiak, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/3543.pdf
    Data publikacji:
    2014
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    body image
    self-perception
    woman
    child-bearing age
    human age
    health
    human health
    Opis:
    Introduction. In psychology, the way in which we perceive our body is what is called “body image”, a concept which is associated with our social and psychical functioning. A positive image of one’s own body is connected with being attractive, having high self-esteem, high self-confidence and general satisfaction with life [1]. Therefore, contentment, or lack thereof, of one’s body comprises an emotional element of body image [2]. The feelings we have towards our body are changing all the time, as well as other behaviours and are conditioned by individual circumstances and mood. Nevertheless, our relationship with the body and its main components are a relatively stable construction [3]. Aim of the study. Recognition of the emotional component of body image of the polled women, and observation of behaviours concomitant with dissatisfaction, lead to improvement of body appearance. Methods and materials. The study was conducted in 2014, in which 200 women of child-bearing age – students of Medical University in Lublin, Poland, participated. The applied measurement tools were a questionnaire and a scale for assessing one’s body, both designed by the authors of the study. Results. The average age of respondents – 22; BMI – 21.1840. In the general “one’s body assessment” scale, the highest mean values were achieved in the subscale of “Aspirations for attaining an ideal figure”. There is a statistically significant correlation between the status of relationship, diet, and aspiration for an ideal figure. Conclusions. Most of the surveyed women were satisfied with their appearance and had a high self-esteem. No statistically significant relations were observed between BMI and the subscales of “General body assessment.” The “Cult of Thin” created by the mass media did not influence the subjective perception of one’s body.
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2014, 08, 2
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The role of bioelements in improving the quality of life of patients suffering form the premenstrual syndrome (PMS)
    Rola biopierwiastków w poprawie jakości życia pacjentek z zespołem napięcia przedmiesiączkowego
    Autorzy:
    Makara-Studzinska, M.
    Morylowska-Topolska, J.
    Sztanke, M.
    Pasternak, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/15638.pdf
    Data publikacji:
    2011
    Wydawca:
    Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
    Tematy:
    bioelement
    life quality
    patient
    premenstrual syndrome
    menstrual cycle
    woman
    magnesium concentration
    zinc concentration
    selenium concentration
    manganese concentration
    Opis:
    The Premenstrual Syndrome (PMS) is described as a cyclical disorder related to the hormonal changes during a menstrual cycle, which affects the emotional and physical health of many women during their reproductive period of life. The PMS can obviously change the quality of life. The syndrome is characterized by a complex group of symptoms, such as depression, irritability, mood swings, anxiety, abdominal discomfort. These signs occur during the luteal phase of a menstrual cycle and disappear after the onset of menses. Some studies suggest that a variety of nutrients may play an important role in the mood swings which occur cyclically during the course of the premenstrual syndrome and that some can have a beneficial impact, especially on the estrous phase of a menstrual cycle. The aim of the paper is to review the results of some studies concerning the role of bioelements in patients with the PMS. Concentrations of magnesium, zinc, selenium and manganese are the highest during menses and the lowest in the ovulatory phase. Fluctuations of the magnesium concentration during a menstrual cycle and the involvement of this element in many cellular pathways and neuromuscular activities obviously affect the incidence or intensity of the PMS symptoms. However, we lack firm evidence that magnesium supplementation can have a positive effect on alleviating the the PMSrelated ailments. Some relationship between the PMS and bone demineralization or depressed calcium concentration in blood has been identified. However, further studies are necessary to examine how the calcium concentration in a human body can decrease the intensity of the PMS symptoms.
    Zespół napięcia przedmiesiączkowego jest opisywany jako cykliczne zaburzenie związane ze zmianami hormonalnymi w cyklu miesiączkowym, które w istotny sposób wpływa na stan emocjonalny i somatyczny wielu kobiet będących w wieku reprodukcyjnym. Zespół napięcia przedmiesiączkowego może negatywnie wpływać na jakość życia. Na zespół ten składa się grupa objawów, takich jak depresja, drażliwość, wahania nastroju, niepokój, dyskomfort w jamie brzusznej. Objawy te pojawiają się podczas fazy lutealnej cyklu menstruacyjnego i znikają tuż po pojawieniu się miesiączki. Opublikowano kilka badań, których wyniki wskazują na to, że różne biopierwiastki mogą odgrywać istotną rolę w cyklicznie pojawiających się w przebiegu zespołu napięcia przedmiesiączkowego zaburzeniach nastroju, a niektóre z nich mogą nawet korzystnie wpływać zwłaszcza na fazę estrogenową cyklu. Celem artykułu jest przegląd wyników badań dotyczących znaczenia biopierwiastków u pacjentek z zespołem napięcia przedmiesiączkowego. Okazuje się, że stężenie magnezu, cynku, selenu i manganu jest najwyższe podczas menstruacji, a najniższe podczas owulacji. Wahania stężenia magnezu w trakcie cyklu miesiączkowego oraz udział tego pierwiastka w wielu przemianach komórkowych oraz w funkcjonowaniu układu nerwowego i mięśniowego wpływają z całą pewnością na pojawienie się oraz nasilenie objawów zespołu napięcia przedmiesiączkowego. Jednak nie ma do tej pory przekonujących dowodów na to, że suplementacja magnezu może mieć pozytywny wpływ na złagodzenie dolegliwości związanych z omawianym zespołem. Stwierdzono zależność między zespołem napięcia przedmiesiączkowego a demineralizacją kości i obniżeniem stężenia wapnia we krwi. Konieczne są jednak dalsze badania dotyczące tego, jak stężenie wapnia w organizmie może wpłynąć na zmniejszenie nasilenia objawów zespołu napięcia przedmiesiączkowego.
    Źródło:
    Journal of Elementology; 2011, 16, 4
    1644-2296
    Pojawia się w:
    Journal of Elementology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Knowledge and opinions of nurses about organ transplantation in a Polish hospital
    Autorzy:
    Makara-Studzinska, M.
    Kowalska, A.
    Wdowiak, A.
    Krys-Noszczyk, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/3557.pdf
    Data publikacji:
    2013
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2013, 07, 1
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Bioelements and eating disorders - aspects of the quality of life
    Biopierwiastki a zaburzenia odzywiania - aspekty jakosci zycia
    Autorzy:
    Makara-Studzinska, M
    Morylowska-Topolska, J.
    Koslak, A.
    Urbanska, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/13987.pdf
    Data publikacji:
    2010
    Wydawca:
    Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
    Tematy:
    bioelement
    eating disorder
    life quality
    anorexia nervosa
    bulimia nervosa
    somatic complication
    medical complication
    Opis:
    Anorexia nervosa and bulimia are emotional disorders which are a serious hazard to the physical health or life. They most often affect girls and young women and disorganize their mental and social life. In this paper, complications caused by eating disorders as a result of deficiency or excessive loss of bioelements by an organism are reviewed along their influence on the quality of life. The symptoms of anorexia nervosa are the following: weight loss over 15% of the standard body mass for the age and height, severe fear of body weight gain despite clear evidence of weight deficiency. The main symptoms of bulimia involve uncontrolled overeating and counteracting weight gain which could occur after overeating episodes by self-induced vomitting or overuse of laxatives and diuretics. Medical complications of bulimia are related to the method and frequency of purgation, while in anorexia they are caused by starvation and weight loss. The following deviations are observed in both restrictive and bulimic forms on anorexia: hypokalemia, hypocalcemia, hypophosphatemia and sometimes also hyponatremia, hypomegnesemia and hypochloremic alkalosis. Many electrolytic and acid abnormalities are found in bulimia depending on the method for laxation (self-induced vomitting, misuse of laxatives or diuretics). Most patients adapt well for a relatively long time to low levels of potassium in plasma but sometimes the situation may cause life threatening consequences, like dysrhythmia, paralytic ileus, neuropathy, muscle weakness and paresis. Physicians and patients should understand that anorexia nervosa is a systemic disease and can affect all body organs. Full knowledge about possible complications of anorexia nervosa allows physicians to achieve precise assessment and conduct appropriate treatment of patients when the diagnosis has already been made.
    Jadłowstręt psychiczny i bulimia to zaburzenia emocjonalne, które poważnie zagrażają zdrowiu fizycznemu, a nawet życiu. Przeważnie występują u dziewcząt i młodych kobiet, dezorganizując ich funkcjonowanie psychospołeczne. W pracy omówiono powikłania zaburzeń odżywiania wynikające z niedoborów lub nadmiernej utraty biopierwiastków przez organizm oraz wpływ tych powikłań na jakość życia. Do objawów jadłowstrętu psychicznego należy: utrata masy ciała powyżej 15% w stosunku do masy należnej dla wieku i wzrostu, nasilony lęk przed zwiększeniem masy ciała, mimo znacznych rzeczywistych niedoborów wagi. Główne objawy bulimii to niekontrolowane objadanie się i przeciwdziałanie przytyciu, które wynikałoby z napadów objadania, czyli prowokowanie wymiotów, nadużywanie środków przeczyszczających, moczopędnych. Komplikacje medyczne bulimii wiążą się ze sposobem i częstością przeczyszczania się, podczas gdy w anoreksji powstają na skutek głodzenia się i utraty wagi. Zarówno w postaci restrykcyjnej, jak i bulimicznej jadłowstrętu wykrywa się następujące odchylenia: hipokaliemię, hipokalcemię, hipofosfatemię, rzadziej hiponatremię, hipomagnezemię i zasadowicę hipochloremiczną, Wiele nieprawidłowości elektrolitowych i kwasowych może pojawić się w bulimii w zależności od tego, czy stosowaną metodą przeczyszczającą jest prowokowanie wymiotów, stosowanie środków moczopędnych lub środków przeczyszczających. Większość pacjentów przez stosunkowo długi czas dobrze przystosowuje do niskich stężeń potasu w surowicy krwi, lecz niekiedy mogą one powodować groźne następstwa: zaburzenia rytmu serca, niedrożność porażenną jelit, neuropatię, osłabienie siły mięśni i ich niedowłady. Lekarze i pacjenci powinni zrozumieć, że jadłowstręt jest chorobą układową, która może dotknąć właściwie wszystkie narządy ciała. Pełna wiedza na temat potencjalnych komplikacji jadłowstrętu pozwala lekarzom na dokładną ocenę i prowadzenie odpowiedniego leczenia pacjentów, kiedy już postawi się diagnozę.
    Źródło:
    Journal of Elementology; 2010, 15, 2; 405-412
    1644-2296
    Pojawia się w:
    Journal of Elementology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Lithium therapy - the effectiveness of the medicine, side symptoms, complications and their influence on the quality of the life in affective diseases
    Terapia litem - skutecznosc leku, objawy uboczne, powiklania i ich wplyw na jakosc zycia w chorobach afektywnych
    Autorzy:
    Makara-Studzinska, M
    Koslak, A.
    Morylowska-Topolska, J.
    Urbanska, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/16186.pdf
    Data publikacji:
    2010
    Wydawca:
    Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
    Tematy:
    lithium therapy
    lithium
    therapy
    medicine
    side symptom
    complication
    life quality
    affective disease
    human disease
    therapeutic effectiveness
    Opis:
    Lithium is a medicine of the first choice in the preventive treatment of bipolar affective disorder. It is also used to enhance the treatment of drug resistant depression. How excatly this element acts is not yet fully understood. Lithium influences the transportation of sodium via cellular membranes (sodium-potassium ATPase dependant), has an inhibitory influence on the second transmitter system (connected with phosphatidylinositol), thus probably acting as a stabiliser of inter cellular processes. Lithium does not associate with plasmatic proteins and is almost entirely excreted by kidneys. The side effects of the medicine are linked to its influence on the central nervous system and on the renal transportation of electrolytes as well as the narrow therapeutic index of the medicine, which can cause intoxication if the recommended doses are not when medical recommendations are not observed. The undesirable effects are more intensive when the level of lithium in the blood plasma increases. Among the most common side effects are stomachaches, nausea, diarrhoea, lack of appetite, polydipsia, polyuria, shaking hands, headaches, sleepiness or deterioration of memory. Complications during lithium therapy listed in literature are ataxia, dysarthria, nystagmus and extrapyramidal symptoms, but the most severe complication is lithium poisoning. Lithium can be applied for a long-term maintenance treatment, which limits recurrence of the disease and improves the patient’s family, social and occupational life. The inferior quality of life among patients with affective disease can result from the disorder itself or can develop on the somatic grounds, appear due to abuse of tobacco or alcohol, or else be a side effect of other medicines taken by the patient. Good co-operation with the patient during the therapy can lessen the pronouncement of undesirable symptoms and complications of a lithium treatment, and this in turn can improve of the quality of the patient’s life.
    Lit jest lekiem pierwszego rzutu w leczeniu profilaktycznym choroby afektywnej dwubiegunowej. Stosowany jest również w celu potencjalizacji leczenia w depresji lekoopornej. Mechanizm działania leku nie jest w pełni poznany. Lit wpływa na transport sodu przez błony komórkowe z udziałem ATP-azy sodowo-potasowej, ma działanie hamujące na układ drugiego przekaźnika związanego z fosfatydyloinozytolem, funkcjonując prawdopodobnie w ten sposób jako stabilizator procesów wewnatrzkomórkowych. Lit nie wiąże się z białkami osoczowymi i prawie całkowicie wydalany jest przez nerki. Objawy uboczne leku mają związek z jego oddziaływaniem na środkowy układ nerwowy, wpływem litu na transport nerkowy elektrolitów oraz wąskim indeksem terapeutycznym leku, co w przypadku nieprzestrzegania zaleceń lekarskich może zagrażać intoksykacją. Nasilenie objawów niepożądanych wzrasta wraz z poziomem litu w surowicy krwi. Wśród najczęściej pojawiających się objawów ubocznych stosowania leku wymienia się bóle brzucha, nudności, biegunkę, brak łaknienia, polidypsję, poliurię, drżenie rąk, bóle głowy, senność, pogorszenie pamięci. Wymieniane w literaturze powikłania terapii litem to: ataksja, dyzartia, oczopląs i objawy pozapiramidowe, a najcięższe powikłanie to zatrucie litem. Lit daje możliwość długoterminowego leczenia podtrzymującego, ograniczającego nawroty choroby, co poprawia funkcjonowanie rodzinne, społeczne i zawodowe chorych. Gorsza jakość życia pacjentów z rozpoznaniem choroby afektywnej może wynikać z samego zaburzenia, przyczyn somatycznych, nadużywania używek, a także skutków ubocznych stosowanych leków. Dobra współpraca pacjenta w terapii wiąże się ze zmniejszeniem wystąpienia objawów niepożądanych i powikłań leczenia litem, przez co może wpływać na poprawę jakości życia pacjentów.
    Źródło:
    Journal of Elementology; 2010, 15, 2; 393-403
    1644-2296
    Pojawia się w:
    Journal of Elementology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Selected protozoal invasions in calves from small and medium-sized farms in the Lublin region
    Autorzy:
    Studzinska, M.
    Tomczuk, K.
    Demkowska-Kutrzepa, M.
    Roczen-Karczmarz, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/6309.pdf
    Data publikacji:
    2016
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    Protozoa
    Apicomplexa
    Eimeria
    Cryptosporidium
    parasite invasion
    prevalence
    diarrhea symptom
    calf
    small farm
    medium-sized farm
    Lublin region
    Źródło:
    Annals of Parasitology; 2016, 62, Suppl.
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Perception and degree of acceptance of menopause-related changes in various spheres of life by postmenopausal women
    Autorzy:
    Robak-Cholubek, D.
    Wdowiak, A.
    Makara-Studzinska, M.
    Korczynska, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/49966.pdf
    Data publikacji:
    2014
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2014, 21, 3
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Alcohol consumption patterns in a group of students at the Medical University in Lublin
    Autorzy:
    Makara-Studzinska, M.
    Sidor, K.
    Podstawka, D.
    Gogacz, M.
    Los, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/3096.pdf
    Data publikacji:
    2012
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2012, 06, 1
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Socio-demographical and psychosocial determinants of anxiety symptoms in a population of pregnant women in the regions of central and eastern Poland
    Autorzy:
    Makara-Studzinska, M.
    Morylowska-Topolska, J.
    Sygit, K.
    Sygit, M.
    Gozdziewska, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/50473.pdf
    Data publikacji:
    2013
    Wydawca:
    Instytut Medycyny Wsi
    Opis:
    Introduction and objective. Until recently, depression and anxiety during pregnancy were a neglected medical problem. The purpose of this study was to determine the prevalence of symptoms of anxiety and depression during pregnancy and identification of the socio-demographic and psychosocial factors. Material and methods. The study was prospective and longitudinal, and the research group consisted of 314 adult pregnant women. To assess the prevalence of anxiety symptoms and depression, the Hospital Anxiety and Depression Scale (HADS) was applied. To assess the psychosocial variables the Rosenberg Self-Assessment Scale, Marital Communication Questionnaire and the Berlin Social Support Scale and authors’ Socio-demographical questionnaire were used. To assess the normal distribution the Shapiro-Wilk test was used. For non-parametric tests the Mann Whitney U test and Kruskal Wallis ANOVA were used due to the distribution of the variables tested against the intergroup comparisons that deviate from the normal distribution. Results and conclusions. Co-existence of anxiety and depression in different trimesters amounted relatively to 12.7% in the first trimester, 10.8% in the second trimester and 12.4% in the third trimester of pregnancy. Symptoms of anxiety were often experienced by unmarried women, non-working women, and those respondents who estimated their housing and financial situation as being worse. Those most susceptible to depressive symptoms were tested women with primary education and those who assessed as worse their financial and housing situation. Higher self-esteem, good communication in a relationship, satisfying social support was associated with a lower incidence of anxiety symptoms during pregnancy. Higher self-esteem, good communication in a relationship, and satisfying social support was associated with a lower incidence of anxiety symptoms during pregnancy.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2013, 20, 1
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Echinococcus multilocuraris –first recorded case of Norway rat (Rattus norvegicus) in Poland
    Autorzy:
    Studzińska, M.B.
    Demkowska-Kutrzepa, M.
    Karamon, J.
    Cencek, T.
    Tomczuk, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/2085210.pdf
    Data publikacji:
    2019
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    Echinococcus multilocuralis
    rodent
    Rattus norvegicus
    intermediate host
    Polska
    Opis:
    Introduction. Echinococcus multilocularis is a very dangerous zoonotic parasite threatening human health. The red fox is the main definitive host, and cats and dogs less commonly. Rats can be intermediate hosts. Objective. The aim of the study was to determine the parasitofauna of Norway rats and some cats and dogs living on a farm near a forest. Materials and method. A parasitological section on 15 Norway rats was conducted. The internal organs were examined by means of macroscopic and microscopic methods. For molecular examination, a QIAmp DNA Mini Kit (Qiagen) was used. Results. Based on necropsy, parasitological and molecular examinations, of the 15 examined rats, 1 was found to have larvae of E. multilocularis, while 3 others had eggs of Hymenolepis diminuta, H. nana and Syphacia obvelata. The faeces of the pets did not contain any developmental forms of parasites. Conclusions. This is the first case of Echinococcus multilocularis infestation in a rat in Poland.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2019, 26, 4; 674-676
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Mental illness and metabolic syndrome-a literature review
    Autorzy:
    Lopuszanska, U.J.
    Skorzynska-Dziduszko, K.
    Lupa-Zatwarnicka, K.
    Makara-Studzinska, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/50055.pdf
    Data publikacji:
    2014
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2014, 21, 4
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Media jako źródło wiedzy o zdrowiu
    Mass-media as a source of health knowledge
    Autorzy:
    Szymczuk, E.
    Zajchowska, J.
    Dominik, A.
    Makara-Studzinska, M.
    Zwolak, A.
    Daniluk, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/4326.pdf
    Data publikacji:
    2011
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Medycyna Ogólna i Nauki o Zdrowiu; 2011, 17(46), 4
    2083-4543
    Pojawia się w:
    Medycyna Ogólna i Nauki o Zdrowiu
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Poziom lęku i depresji w okresie okołooperacyjnym a kategoria zabiegu operacyjnego w grupie kobiet leczonych z powodów ginekologicznych
    Level of anxiety and depression in the perioperative period and category of surgical procedure in a group of women treated for gynaecological reasons
    Autorzy:
    Lewicka, M.
    Makara-Studzinska, M.
    Wdowiak, A.
    Sulima, M.
    Kanadys, K.
    Wiktor, H.
    Powiązania:
    https://bibliotekanauki.pl/articles/4516.pdf
    Data publikacji:
    2012
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Medycyna Ogólna i Nauki o Zdrowiu; 2012, 18(47), 2
    2083-4543
    Pojawia się w:
    Medycyna Ogólna i Nauki o Zdrowiu
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Analysis of the phenomenon of attempted suicides in 1978-2010 in Poland, with particular emphasis on rural areas of Lublin Province
    Autorzy:
    Makara-Studzinska, M.
    Sygit, K.
    Sygit, M.
    Gozdziewska, M.
    Zubilewicz, J.
    Krys-Noszczyk, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/50160.pdf
    Data publikacji:
    2012
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2012, 19, 4
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Comparison of the effectiveness of selected essential oils with mineral oil and spinosad on Dermanyssus gallinae
    Autorzy:
    Roczeń-Karczmarz, M.
    Demkowska-Kutrzepa, M.
    Zdybel, J.
    Szczepaniak, K.
    Studzińska, M.
    Tomczuk, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/16539169.pdf
    Data publikacji:
    2022
    Wydawca:
    Polska Akademia Nauk. Czasopisma i Monografie PAN
    Tematy:
    Dermanyssus
    mite
    essential oil
    mineral oil
    spinosad
    Opis:
    It seems that essential oils can be a good ingredient in effective preparations against Dermanyssus gallinae. Dermanyssus affects animal health leading to financial losses and bird welfare issues. Collected mites were treated with various essential oils in four (20, 50, 80 and 100%) concentrations at a dose of 0.28 mg/cm2. The direct toxicity of the essential oils, mineral oil and spinosad to D. gallinae was tested in the laboratory. Eucalyptus oil was the most toxic essential oil in all concentrations to D. gallinae (87.6 - 97.6% mortality at all four concentrations), while geranium, pine and rosemary oils showed mortality rates of 14.2 - 68.2%. High mortality after 48 hours of contact was also recorded for the oil of cloves at 80% dilution (85.1% mortality), lavender 100% (94.2% mortality). Similarly, the thyme essential oil produced 83.5 - 93.2% mortality in three concentrations: 50, 80 and 100%. The mineral oil was the least effective oil against mites. Spinosad showed high effectiveness against D. gallinae.
    Źródło:
    Polish Journal of Veterinary Sciences; 2022, 25, 2; 261-268
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Coaching as a method for potentially reducing the risk of burnout in medical professionals
    Autorzy:
    Sułkowska, J.
    Kuźmicz, I.
    Malinowska-Lipień, I.
    Lickiewicz, J.
    Brzostek, T.
    Makara-Studzińska, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918569.pdf
    Data publikacji:
    2017
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    coaching
    burnout
    medical professions
    nurses
    physicians
    Opis:
    In their daily work, medical professionals often encounter emotionally and mentally challenging situations, such as sudden health deterioration or death of their patients. The concern to ensure the highest possible level of healthcare and meet all the standards despite the limitations that come with working under the pressure of time, the interactions with other individuals, the physical burden and stress, as well as with the (sometimes limited) support from superiors and lack of satisfaction with salary may, as a result, translate into a higher risk of burnout. Research indicates a potential effectiveness of coaching with respect to medical personnel. However, there are no publications available concerning nurse-oriented coaching, which would be intended to reduce the risk of burnout in this professional group. The objective of this paper is to present coaching as a method that makes it possible to reduce the risk related to burnout in medical professionals.
    Źródło:
    Progress in Health Sciences; 2017, 7(2); 85-92
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Evaluation of symptoms of anxiety and depression in women with breast cancer after breast amputation or conservation treated with adjuvant chemotherapy
    Autorzy:
    Kaminska, M.
    Kubiatowski, T.
    Ciszewski, T.
    Czarnocki, K.J.
    Makara-Studzinska, M.
    Bojar, I.
    Staroslawska, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/50492.pdf
    Data publikacji:
    2015
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2015, 22, 1
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Metody zapobiegania ciąży w ocenie kobiet w wieku rozrodczym a deklarowana istotność wiary katolickiej -badania pilotażowe
    Contraceptive methods in the view of women at reproductive age and the declared importance of the Catholic faith - a pilot study
    Autorzy:
    Rutkowska, A.
    Rolinska, A.
    Milanowska, J.
    Kowalska, A.J.
    Krys, K.
    Sidor, K.
    Makara-Studzinska, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/4025.pdf
    Data publikacji:
    2012
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Medycyna Ogólna i Nauki o Zdrowiu; 2012, 18(47), 2
    2083-4543
    Pojawia się w:
    Medycyna Ogólna i Nauki o Zdrowiu
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The current invasiological status of pigeon flocks in the vicinity of Lublin, based on coproscopic studies
    Autorzy:
    Tomczuk, K.
    Studzinska, M.
    Szczepaniak, K.
    Grzybek, M.
    Demkowska-Kutrzepa, M.
    Roczen-Karczmarz, M.
    Abbass, Z.A.
    Powiązania:
    https://bibliotekanauki.pl/articles/6355.pdf
    Data publikacji:
    2016
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    bird
    pigeon
    invasion
    flock
    parasite
    intestinal parasite
    animal parasite
    prevalence
    Lublin city
    coproscopy
    Źródło:
    Annals of Parasitology; 2016, 62, Suppl.
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Capillariidae family infection in bats living in Upper Silesia, Poland
    Autorzy:
    Roczen-Karczmarz, M.
    Zyla, S.
    Klys, G.
    Tomczuk, K.
    Szczepaniak, K.
    Grzybek, M.
    Studzinska, M.
    Demkowska-Kutrzepa, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/6461.pdf
    Data publikacji:
    2016
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    Capillariidae
    Capillaria
    nematode
    animal infection
    bat
    Myotis myotis
    Upper Silesian region
    Polska
    Źródło:
    Annals of Parasitology; 2016, 62, Suppl.
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Life quality of women with breast cancer after mastectomy or breast conserving therapy treated with adjuvant chemotherapy
    Autorzy:
    Kaminska, M.
    Ciszewski, T.
    Kukielka-Budny, B.
    Kubiatowski, T.
    Baczewska, B.
    Makara-Studzinska, M.
    Staroslawska, E.
    Bojar, I.
    Powiązania:
    https://bibliotekanauki.pl/articles/49364.pdf
    Data publikacji:
    2015
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2015, 22, 4
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Quality of life and occurrence of depression under chemotherapy in patients suffering from lung carcinoma
    Autorzy:
    Baczewska, B.
    Kaminska, M.
    Ciszewski, T.
    Kubiatowski, T.
    Makara-Studzinska, M.
    Sygit, K.
    Sygit, M.
    Zubilewicz, J.
    Pietrzak, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/51308.pdf
    Data publikacji:
    2014
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2014, 21, 4
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Potential sources of infection with selected zoonotic agents in the veterinary work environment - pilot studies
    Autorzy:
    Wójcik-Fatla, A.
    Sroka, J.
    Zając, V.
    Sawczyn-Domańska, A.
    Kloc, A.
    Zwoliński, J.
    Kłapeć, T.
    Studzińska, M.B.
    Chmura, R.
    Dutkiewicz, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/2085448.pdf
    Data publikacji:
    2020
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    environment
    Coxiella burnetii
    Toxoplasma gondii
    veterinarians
    Leptospira spp
    Cryptosporidium spp
    Giardia duodenalis
    Opis:
    Introduction and Objective. The problem of occupational biohazards is very important, especially in the field of agriculture and in human and veterinary medicine. The aim of the study was to determine the potential sources of infection in veterinary professionals with selected zoonotic agents, including: Toxoplasma gondii, Giardia duodenalis, Leptospira spp., Cryptosporidium spp. and Coxiella burnetii. Materials and Method. A total of 50 air samples from barns, piggeries and veterinary surgeries were examined for the presence of Leptospira spp. and C. burnetii DNA. Serum samples of 86 pigs and 80 cows were tested for the presence of antibodies to Leptospira spp. and to phase I and II C. burnetii antigens. Serum of 70 cats were tested for the presence of antibodies to T. gondii and 65 samples of cat faeces for the presence of T. gondii oocysts. The presence of G. duodenalis and Cryptosporidium spp. were examined in 50 of dog faeces and 50 of bovine faeces samples. Results. DNA of Leptospira spp. was detected in 2 air samples from the piggeries (4%). C. burnetii DNA was not found in any sample. Anti-Leptospira spp. antibodies were detected in 51 (59.3%) of examined pigs. Neither anti-Leptospira spp. nor anti-C. burnetii antibodies were found among samples of bovine serum. Anti-T. gondii antibodies was found in 52 cat serum samples (74.3%). Among samples of cat faeces, no T. gondii oocysts were detected. In one sample of cattle stool (2%), G. duodenalis was detected and in another (2%) – Cryptosporidium spp. G. duodenalis was detected in 7 samples (14%) and Cryptosporidium spp. in 2 samples (2%) of dog faeces. Conclusions. The results of this study demonstrate the potential risk of infection with Leptospira spp. in veterinarians working with pigs. Veterinarians could be also be at risk of infection with T. gondii and G. duodenalis.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2020, 27, 1; 146-150
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Prolina : pospolity aminokwas wyjątkowy katalizator. Część IV, Reakcja Michaela
    Proline as a common amino acid and an exceptional catalyst. Part IV, Michael reaction
    Autorzy:
    Karczmarska-Wódzka, A.
    Studzińska, R.
    Kołodziejska, R.
    Wróblewski, M.
    Dramiński, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/171840.pdf
    Data publikacji:
    2014
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Tematy:
    prolina
    reakcja Michaela
    synteza asymetryczna
    proline
    Michael reaction
    asymmetric synthesis
    Opis:
    In recent years there has been a dynamic development of asymmetric synthesis. Groups of researchers, particularly the one led by Benjamin List and Carlos Barbas, carried out a number of reactions and showed the effectiveness of the use of small organic molecules such as proline as catalysts. Michael addition catalyzed with proline is a particularly interesting reaction because it can be carried out in two aminocatalytic pathways. The analysis of Michael reaction reveals potential for both forms of aminocatalysis: enamine and iminium catalysis (Scheme 1) [1–14]. Presumably Michael reaction proceeds mainly according to enamine mechanism. The use of proline in Michael reaction with imine activated acceptor is slightly effective. So far the researches have shown that the modification of proline molecule or addition of other catalyst is necessary for condensation to appear. Enamine catalysis concerns the activation of carbonyl compound in situ being a donor. There is no need for enolase anion to be created earlier [2, 15–17]. When, as a result of the reaction of a,b-unsaturated carbonyl compound with proline, Michael acceptor activation appears it means that it is enamine mechanism reaction (Scheme 1) [2, 24]. One of the first examples of direct Michael reaction proceeding through enamine transition state is the reaction of cyclopentanone with nitrostyrene (Scheme 6) [20–23]. Other examples of Michael addition of ketone with nitro olefin catalysed by proline are shown in table 2 and 3 [10, 23, 30]. Nitroketones obtained in that way are useful as precursors for different organic compounds [33], also pyrrolidines [34]. Pyrrolidines are pharmacologically active and they selectively block presynaptic dopamine receptors [34] (Scheme 7). Except for Michael intermolecular reaction, intramolecular condensation adducts were also obtained. Michael intramolecular proline-catalyzed condensation in which inactive ketones transform into α,β-unsaturated carbonyl compounds was described (Scheme 9) [35, 36]. These reactions require a stoichiometric amount of a catalyst and a long time of reaction and they give as a result a little enantiomeric excess [11, 24, 35]. In 1991, Yamaguchi and co-workers carried out malonates Michael addition to α, β-unsaturated aldehydes catalyzed by L-proline [24, 39]. The reaction proceeded according to enamine mechanism, for example dimethyl malonate was reacted with hex- 2-enal in the presence of proline to give Michael adduct in 44% yield. To improve the yield an attempt of a slight modification of a proline molecule was made transforming it into proper salt. Proline lithium salt enabled to obtain the condensation product in 93% yield (Tab. 4). Regardless of a used catalyst the products in the form of racemates were obtained. In order to improve enantioselective properties of a catalyst, Michael addition of diisopropyl malonate to cycloheptenone was carried out in chloroform in the presence of different proline salts. Optimal enantioselectivity and yield was obtained by using rubidium salt (Tab. 5–7) [40, 41]. Rubidium prolinate-catalyzed Michael additions are used in industry e.g. for enantioselective synthesis of the selective serotonine reuptake inhibitior (SSRI) (–)-paroxetine (antidepressant) (Scheme 12) [24].
    Źródło:
    Wiadomości Chemiczne; 2014, 68, 1-2; 49-65
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Prolina : pospolity aminokwas wyjątkowy katalizator. Część III, Reakcja Mannicha
    Proline as a common amino acid and an exceptional catalyst. Part III, Mannich reaction
    Autorzy:
    Studzińska, R.
    Karczmarska-Wódzka, A.
    Wróblewski, M.
    Kołodziejska, R.
    Dramiński, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/172649.pdf
    Data publikacji:
    2014
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Tematy:
    prolina
    reakcja Mannicha
    synteza asymetryczna
    proline
    Mannich reaction
    asymmetric synthesis
    Opis:
    Mannich reaction occuring among ketone, aldehyde, and amine is one of the ways of a synthesis of biologically active compounds. Reactions of this type were carried out in the presence of different catalysts [3–10], however in recent years a lot of attention has been paid to enantioselective Mannich reaction catalyzed with proline. Such reactions were carried out with the use of different compounds containing carbonyl group and the most frequently used amine was p-anisidine. The advantage of the use of p-anisidine is a possibility of conducting the direct Mannich reaction (Scheme 3). In this way β-amino ketones (Tab. 1, 2, 4) [15, 18–20, 23, 24], α-hydroxy-β-amino ketones (Tab. 3) [15, 22], and β-amino alcohols (Tab. 5, 6) [25, 26] were obtained. A possibility of syntheses of β-amino sugars and α-amino acids with their derivatives (Tab. 7) [28, 29] is worth noticing. In a great number of described reactions, the products were obtained with satisfactory yield and enantiomeric excess. Taking into consideration the difficulty of a removal of p-hydroxyphenyl group which protects amine group in the resulting products, the attempts of using different amine compounds in Mannich reactions catalyzed with proline were undertaken. The use of amines blocked by tert-butoxycarbonyl group (Boc) enabled to obtain the products with high yield and ee values (Tab. 12–15) [35–38]. However in the case of the use of Boc the reaction must be carried out in an indirect way (it is necessary to prepare imine blocked by Boc earlier).
    Źródło:
    Wiadomości Chemiczne; 2014, 68, 1-2; 21-48
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Prolina – pospolity aminokwas wyjątkowy katalizator. Część II, Międzycząsteczkowa kondensacja aldolowa
    Proline as a common amino acid and an exceptional catalyst. Part II, Intermolecular aldol reaction
    Autorzy:
    Kołodziejska, R.
    Wróblewski, M.
    Karczmarska-Wódzka, A.
    Studzińska, R.
    Dramiński, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/171560.pdf
    Data publikacji:
    2013
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Tematy:
    międzycząsteczkowa reakcja aldolowa donor
    akceptor
    prolina
    anti-aldole
    intermolecular aldol reaction
    donor
    acceptor
    proline
    anti-aldol
    Opis:
    Proline in organic synthesis is used as a small molecular organocatalyst. In a catalytic act proline, similarly to an enzyme, activates reagents, stabilizes transition state and influences an orientation of substrates [1–12]. Proline works as aldolase I (so called microaldolase I). In comparison with other amino acids it shows exceptional nucleophilicity which makes imines and enamines formation easier. In the intermolecular aldol reaction proline was used for the first time by List and co-workers (Scheme 1) [3, 9, 20]. Since then an immense progress has been observed in this field. Several aldolization reactions were performed in the presence of proline. Reactions of this type proceed between the donor (nucleophile) and the acceptor (electrophile). In aldol reaction the donors can be both ketones and aldehydes which next are condensed with ketones and aldehydes acting as electrophiles (Scheme 2–18; Tab. 1–7) [21–72]. The presence of proline ensures not only high yield of homo- and heteroaldolization but mainly enables conducting enantio- and diastereoselective synthesis. Intermolecular proline-catalyzed aldol condensation proceeds according to enamine mechanism. Anti-aldols, which make a valuable source of intermediates in the synthesis of important biologically active compounds, are mainly obtained in this reaction [35–44, 54, 58, 62, 63, 68, 69, 71].
    Źródło:
    Wiadomości Chemiczne; 2013, 67, 11-12; 1027-1050
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Prolina – pospolity aminokwas wyjątkowy katalizator. Część I, Biosynteza proliny. Wewnątrzcząsteczkowa kondensacja aldolowa
    Proline as a common amino acid and an exceptional catalyst. Part I, Proline biosynthesis. Intramolecular aldol reaction
    Autorzy:
    Wróblewski, M.
    Kołodziejska, R.
    Studzińska, R.
    Karczmarska-Wódzka, A.
    Dramiński, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/172473.pdf
    Data publikacji:
    2013
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Tematy:
    biosynteza proliny
    mechanizm kondensacji aldolowej
    wewnątrzcząsteczkowa reakcja aldolowa
    proline biosynthesis
    mechanism of aldol reaction
    intramolecular aldol reaction
    Opis:
    In asymmetric synthesis of organic compounds more effective solutions are being looked for which will result in higher yield(s) of product(s) and their high enantioselectivity [1]. One of such solutions is an use of a multilevel and cheap catalyst. Proline used as a catalyst is a substance of natural origin which was synthetically obtained by Willstätter who was carrying out research on hygric acid (Scheme 1) [10]. The cells of many organisms have a suitable enzymatic system essential for proline biosynthesis [15]. So far, three proline biosynthesis pathways have been described: from glutamate (Scheme 3 and 4), ornithine (Scheme 5 and 6), and arginine (Scheme 7) [16–28]. Proline which is obtained as a result of biosynthesis or supplementation is a substrate for many proteins. Characteristic and significant content (about 23%) of this amino acid was observed in collage. In cells proline can play an important role of osmoregulator [31–35] – a protective substance regulating the activity of such enzymes as catalase and peroxidase [36]. Proline as a secondary amine shows exceptional nucleophilicity facilitating imine and enamine formation. Used as a catalyst in aldol reaction makes with substrates like imine or enamine transition state imitating the activity of naturally occurring enzymes for this type of reaction, that is aldolases. In their research Hajos and Parrish, and Eder, Sauer and Wiechert used proline in intramolecular aldol reaction obtaining proper enones (Scheme 9) [60–62]. The process of intramolecular aldol reaction was used for a separation of racemic mixture of diketones (Scheme 10) [63, 64], cyclization of ortho-substituted aromatic aldehydes and ketones (Scheme 11) [65], synthesis of cyclic diketones (Scheme 13) [68] and domino reaction to obtain substituted cyclohexanones from beta-diketones and unsaturated ketones (Scheme 14) [69].
    Źródło:
    Wiadomości Chemiczne; 2013, 67, 9-10; 801-818
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Asymetryczne przeniesienie wodoru do ketonów katalizowane związkami Rutenu(II) i Rodu(III)
    Asymmetric transfer hydrogenation of ketones catalyzed by Ruthenium(II) and Rhodium(III) complexes
    Autorzy:
    Karczmarska-Wódzka, A.
    Kołodziejska, R.
    Studzińska, R.
    Wróblewski, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/172550.pdf
    Data publikacji:
    2012
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Tematy:
    transfer wodoru asymetryczny
    związki kompleksowe Ru(II) i Rh(III)
    chiralne ligandy
    prochiralne związki karbonylowe
    asymmetric transfer hydrogenation
    Ru(II) and Rh(III) complexes
    chiral ligands
    prochiral carbonyl compounds
    Opis:
    Asymmetric hydrogen transfer (ATH) is one of the methods of stereoselective reduction of prochiral carbonyl compounds (Scheme 6). Complexes of the platinum group metals (Noyori catalysts) are the most common catalysts for AT H reactions. The specific structure of the Noyori catalyst allows to activate two hydrogen atoms. These atoms are transferred from donor to acceptor in the form of hydride ion and proton (Scheme 1). Depending on the used catalyst the transfer hydrogenation of ketons can proceed by direct and indirect transfer mechanism. The direct hydride transfer from a donor to an acceptor proceeds via a six-membered transition state (3) (Scheme 2). The indirect hydride transfer proceeds through the formation of an intermediate metal hydride. A monohydride (HLnMH) and or a dihydride (LnMH2) can be formed depending on the catalyst that is used (Scheme 3). In the monohydride route, the reduction proceeds in the inner sphere of the metal (four-membered transition state (4)) or in the outer sphere of the metal (six-membered transition state (5)) (Scheme 4). The proposed reduction of carbonyl compounds in the AT H reaction by Noyori catalysts uses the mechanism of the hydride ion and proton transfer from the donor to the catalyst and the formation of the monohydride. In the indirect transfer hydrogenation the hydride ion and proton are transferred from the monohydride to the acceptor (Scheme 5, 7). AT H reactions that lead to chiral alcohols are conducted in organic solvents or in water. Hydrogen donors most often used in organic solvent reactions are propan-2-ol or an azeotropic mixture of formic acid and triethylamine (Tab. 1, 6). Sodium formate is usually used as hydrogen donor in the reactions conducted in water. Yield and enantioselectivity of the reaction depend on many factors the most important of which are: the structure of a substrate, hydrogen donor and solvent that were used, the reaction time, substrate concentration, and the S/C ratio [2]. In the case of asymmetric reduction conducted in water the solvent pH is also of great importance [3, 7, 8]. An optimal pH range depends on the type of a catalyst [7, 8]. AT H reactions conducted in water are distinguished by a shorter reaction time and higher enantioselectivity than the reactions conducted in organic solvents. In addition, catalysts used in the AT H reactions are more stable in water allowing reuse of the catalyst without loss of its activity. This paper presented examples of the use of specific catalysts in asymmetric reactions of hydrogen transfer. In particular, I drew attention to the reactions running in the aquatic environment due to the above-mentioned advantages of this solvent. The authors focused specifically on bifunctional catalysts based on Ru(II) and Rh(III) on the account of wide usage of the catalysts of that type in AT H reactions in water and their good performance [8, 9, 15, 16, 17, 19, 20, 21, 22]. p-Cymene is the most common aromatic ligand in catalysts based on Ru(II) while in the case of catalysts with Rh(III) the most common is anionic pentamethylcyclopentadienyl ligand. In both cases the second most common ligands are diamines or amino alcohols (Scheme 8). There are better performance and enantioselectivity when diamines are used as ligands. Attempts to replace diamines and amino alcohols by Schiff bases (Scheme 13) in the catalysts containing Rh(III) proved poor results due to a very low enantioselectivity of conducted reactions (Tab. 7).
    Źródło:
    Wiadomości Chemiczne; 2012, 66, 3-4; 273-295
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The lichen molecular bioindicator of CO2 pollution of air
    Autorzy:
    Pawlowski, M.
    Skrzypczak, A.
    Studzinska-Sroka, E.
    Bylka, W.
    Bialek-Bylka, G.
    Powiązania:
    https://bibliotekanauki.pl/articles/80878.pdf
    Data publikacji:
    2013
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    conference
    lichen
    carbon dioxide
    air pollution
    molecular bioindicator
    ionic liquid
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Enancjoselektywna enzymatyczna desymetryzacja katalizowana lipazami. Część 1, Związki prochiralne
    Enantioselectve enzymatic desymmetrization catalyzed in the presence of lipase. Part 1, Prochiral compounds
    Autorzy:
    Kołodziejska, R.
    Karczmarska-Wódzka, A.
    Tafelska-Kaczmarek, A.
    Studzińska, R.
    Dramiński, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/171684.pdf
    Data publikacji:
    2013
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Tematy:
    związki prochiralne
    desymetryzacja
    transestryfikacja
    hydroliza
    lipazy
    prochiral compounds
    desymmetrization
    transesterification
    hydrolysis
    lipase
    Opis:
    In the enzymatic asymmetric synthesis, the enzyme allows the desymmetrization of achiral compounds resulting in chiral compounds of high optical purity. Therefore, this type of biotransformation is known as enantioselective enzymatic desymmetrization (EED) [1–11]. This method is related to the generation of an asymmetry (loss of symmetry elements) in prochiral molecules (most often an sp3 or sp2 hybridized carbon atom), in meso synthones, and centrosymmetric compounds. An achiral center of the tetrahedral system is defined as a prochiral one if it becomes chiral as a result of one of the two substituents replacement which, when separated from the particles, are indistinguishable (Scheme 1, 2) [1–4, 9, 12]. Asymmetric synthesis is enantioselective when one of the enantiotopic groups or faces of an optically inactive compound is biotransformed faster than the other (Scheme 3–5) [1, 10, 11, 13–15]. Lipases are enzymes of highest importance in stereoselective organic synthesis, mainly due to their exceptionally broad substrate tolerance, stability, activity in unphysiological systems, and relatively low price [9, 14]. The mechanism of enzymatic hydrolysis catalysed by hydrolases is similar to that observed in the chemical hydrolysis with the use of base. The selectivity of enzymatic catalysis depends on the substrate orientation in the enzyme active site (Scheme 6, 7) [25–29]. Lipases were successfully used for the desymmetrization of different prochiral diesters, alcohols and amines. Most lipases preferentially convert the same prochiral groups in the above mentioned types of reaction. This allows the preparation of the both enantiomers of the product in high chemical and optical yield (Scheme 9–13) [9, 13, 32–56].
    Źródło:
    Wiadomości Chemiczne; 2013, 67, 7-8; 751-772
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Enancjoselektywna enzymatyczna desymetryzacja katalizowana oksydoreduktazami. Dehydrogenazy w reakcji redukcji. Część I
    Enantioselective enzymatic desymmetrization catalyzed by oxidoreductases. Dehydrogenases in reduction reactions. Part I
    Autorzy:
    Kołodziejska, R.
    Karczmarska-Wódzka, A.
    Tafelska-Kaczmarek, A.
    Studzińska, R.
    Wróblewski, M.
    Augustyńska, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/171686.pdf
    Data publikacji:
    2014
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Tematy:
    redukcja asymetryczna
    dehydrogenaza alkoholowa
    kofaktor
    asymmetric reduction
    alcohol dehydrogenase
    cofactor
    Opis:
    Enzymes act as biocatalysts whether are also mediating in all anabolic and catabolic pathways, playing an extremely important role in the cells of all life forms. Catalytic potential of oxidoreductases is most commonly used in reduction reactions. Dehydrogenases and reductases catalyze the reversible desymmetrization reactions of meso and prochiral carbonyl compounds and alkenes. The oxidoreductase- catalyzed reactions require cofactors to initiate catalysis. In most cases, it is nicotinamide adenine dinucleotide (NADH) or its phosphorylated derivative (NADPH), which acts as a hydride donor. The necessity of employing expensive cofactors was, for the long time, one of the main limitations to the use of dehydrogenases. This problem was solved by developing a regeneration system of a cofactor in the reaction environment. Various systems are used for the cofactor recycling. In the case of a carbonyl compound reduction, an irreversible oxidation of formic acid to carbon dioxide is most frequently used. In this paper, selected examples of whole-cell and isolated enzymes applications in the carbonyl compound reduction are discussed. The application of baker’s yeast, microorganisms and dehydrogenases in enantioselective enzymatic desymmetrization (EED) of prochiral ketones leads to a broad spectrum of chiral alcohols used as intermediates in the syntheses of many pharmaceuticals and compounds presenting a potential biological activity.
    Źródło:
    Wiadomości Chemiczne; 2014, 68, 9-10; 763-782
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Enancjoselektywna enzymatyczna desymetryzacja katalizowana oksydoreduktazami. Reakcje redukcji. Część 2
    Enantioselective enzymatic desymmetrization catalyzed by oxidoreductases. Reduction reactions. Part 2
    Autorzy:
    Kołodziejska, R.
    Karczmarska-Wódzka, A.
    Tafelska-Kaczmarek, A.
    Studzińska, R.
    Wróblewski, M.
    Augustyńska, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/171910.pdf
    Data publikacji:
    2014
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Opis:
    Biotransformation reactions of many organic compounds under the influence of enzymes take place with the high selectivity, rarely achieved by other methods. Ketoesters represent an extensive group of selectively bioreduced compounds. Chiral hydroxyesters and, subsequently, hydroxyacids are valuable intermediates in the syntheses of various biologically active compounds. Acyclic α- and β-ketoesters are transformed to the corresponding (R)- and (S)-hydroxyesters by using a specific dehydrogenases. The whole-cells enzymes, e.g. baker’s yeast, may exhibit a different catalytic activity depending on the substrate structure. Baker’s yeast enzymes selectively reduce the cyclic β-ketoesters providing mainly anti diastereomers due to the lack of rotation around the single α,β carbon-carbon bond. The enzymatic reduction of the esters, cyclopentanone, and cyclohexanone derivatives gave the optically active anti-alcohol enantiomers. The reductive EED of prochiral α-ketoesters, as well as β-ketoesters is an interesting transformation in organic chemistry due to the importance of the resulting chiral α-hydroxy acids and their derivatives used as building blocks. Baker’s yeast-catalyzed reduction of alkyl esters derived from pyruvate and benzoylformate allows the preparation of the (R)-alcohols. Polyketones can also be subjected to the reductive EED to give different compounds bearing the quaternary stereogenic centers which are broadly applied in asymmetric synthesis. In asymmetric synthesis, similarly to carbon-oxygen double bonds, carbon-carbon double bonds of prochiral alkanes can be reduced to obtain the optically active saturated compounds. The reduction of alkenes is catalyzed by both, the whole cells (microorganisms, plant cells) as well as isolated enzymes belonging to the oxydoreductases, so-called ene-reductases. The whole-cell catalysts are suitable, most frequently, for the preparative scale syntheses, but they are less chemoselective in comparison to the isolated reductases. In the case of polyfunctionalized alkenes, microorganisms can cause the additional side reaction reducing the desired product yield.
    Źródło:
    Wiadomości Chemiczne; 2014, 68, 11-12; 1009-1030
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Enancjoselektywna enzymatyczna desymetryzacja katalizowana oksydoreduktazami. Reakcje utleniania. Część 2
    Enantioselective enzymatic desymmetrization catalyzed by oxidoreductases. Oxidation reactions. Part 2
    Autorzy:
    Karczmarska-Wódzka, A.
    Kołodziejska, R.
    Tafelska-Kaczmarek, A.
    Studzińska, R.
    Wróblewski, M.
    Augustyńska, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/172457.pdf
    Data publikacji:
    2015
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Tematy:
    dioksygenaza
    oksydaza
    peroksydaza
    reakcja utleniania
    dioxygenase
    oxidase
    peroxidase
    oxidation reaction
    Opis:
    In continuation of our work, we herein describe next enzyme classes applied for oxidation reaction. Dioxygenases, oxidases, and peroxidases are successfully used in the synthesis of desymmetrization products with high yields and enantiomeric excesses. Aromatic dioxygenases, such as toluene dioxygenase (TDO), naphthalene dioxygenase (NDO), and biphenyl dioxygenase (BPDO) found in the prokaryotic microorganisms are enzymes belonging to the dioxygenase class and are the most commonly used in organic synthesis. The α-oxidation of various fatty acids in the presence of an α-oxidase from germinating peas is one of the few examples of oxidases application in asymmetric organic synthesis. The intermediary α-hydroxyperoxyacids can undergo two competing reactions: decarboxylation of the corresponding aldehydes or reduction to the (R)-2-hydroxy acids. In order to eliminate the competitive decarboxylation reaction tin(II) chloride is used as an in situ reducing agent. Peroxidases are the redox enzymes found in various sources such as animals, plants, and microorganisms. Due to the fact that, in contrast to monooxygenases, no additional cofactors are required, peroxidases are highly attractive for the preparative biotransformation. Oxidation reactions catalyzed by (halo)peroxydases are also often used in organic synthesis. N-Oxidation of amines, for instance, leads to the formation of the corresponding aliphatic N-oxides, aromatic nitro-, or nitrosocompounds. From a preparative synthesis standpoint, however, sulfoxidation of thioether is important since it was proven to proceed in a highly stereo- and enantioselective manner. Furthermore, depending on the source of haloperoxidase, chiral sulfoxides of opposite configurations can be obtained.
    Źródło:
    Wiadomości Chemiczne; 2015, 69, 1-2; 53-64
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Enancjoselektywna enzymatyczna desymetryzacja katalizowana oksydoreduktazami. Reakcje utleniania. Część 1
    Enantioselective enzymatic desymmetrization catalyzed by oxidoreductases. Oxidation reactions. Part 1
    Autorzy:
    Karczmarska-Wódzka, A.
    Kołodziejska, R.
    Tafelska-Kaczmarek, A.
    Studzińska, R.
    Wróblewski, M.
    Augustyńska, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/172799.pdf
    Data publikacji:
    2015
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Tematy:
    dehydrogenaza
    monooksygenaza
    reakcja utleniania
    dehydrogenase
    monooxygenase
    oxidation reaction
    Opis:
    The main advantage of biotransformation involving enzymes, compared to chemical processes, is a highly selective formation of products with precise configuration. Herein we describe enzymes participating in the oxidation processes, especially dehydrogenases and monooxygenases. Dehydrogenases are not only able to catalyze the enantioselective reduction of prochiral ketones, but they can also desymmetrize meso and prochiral diols through the enantioselective oxidation. As a result of this processes, optically active hydroxyketones, hydroxycarboxylic acids, and their derivatives are obtained. Cytochrome P450 monooxygenases (CYPs) constitute a family of heme-containing enzymes which exhibits a variety of catalytic activities. They catalyze different reactions, such as hydroxylation, epoxidation, oxidative deamination, or N- and (S)-oxidation. In the oxidation reaction with monooxygenases, the whole cells are commonly used as catalysts. The use of monooxygenases in the oxidation reaction of prochiral alkanes provides the optically active alcohols. It is very significant that these transformations are still difficult to carry out by chemical methods. Baeyer-Villiger monooxygenases (BVMO EC 1.14.13.X) effectively catalyze the nucleophilic and electrophilic oxidation reactions of various functional groups. BVMO are highly regio- and stereoselective enzymes, and their catalytic potential is used in the synthesis of optically pure lactones and esters. Keywords:
    Źródło:
    Wiadomości Chemiczne; 2015, 69, 1-2; 35-51
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Fabrication and properties of the field emission array with self-alignment gate electrode
    Autorzy:
    Barth, W.
    Dębski, T.
    Rangelow, I.W.
    Grabiec, P.
    Studzińska, K.
    Zaborowski, M.
    Mitura, S.
    Biehl, S.
    Hudek, P.
    Kostic, I.
    Powiązania:
    https://bibliotekanauki.pl/articles/308414.pdf
    Data publikacji:
    2001
    Wydawca:
    Instytut Łączności - Państwowy Instytut Badawczy
    Tematy:
    field-emission array
    field emission display
    diamond-like-carbon layers emission
    silicon micromachining
    self-alignment technology
    Opis:
    A new method for the fabrication of field emission arrays (FEA) based on bulk/surface silicon micromachining and diamond-like-carbon (DLC) coating was developed. A matrix of self-aligned electron field emitters is formed in silicon by mean anisotropic etching in alkali solution of the front silicon film through micro holes opened in silicon oxide layer. The field emission of the fabricated emitter tips is enhanced by a diamond-like-carbon film formed by chemical vapor deposition on the microtips. Back side contacts are formed by metal patterning. Detailed Raman, Auger and TEM investigations of the deposited DLC films (nanocrystalline diamond smaller than 10 nm) will be presented. In this paper we discuss the problems related to the development of field emission arrays technology. We also demonstrate examples of devices fabricated according to those technologies.
    Źródło:
    Journal of Telecommunications and Information Technology; 2001, 1; 49-52
    1509-4553
    1899-8852
    Pojawia się w:
    Journal of Telecommunications and Information Technology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
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