Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Yкраїнський (UK)
Przejdź do strony domowej biblioteki Centralna Biblioteka Wojskowa Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaCentralna Biblioteka Wojskowa

Wyszukujesz frazę "chitosan hydrogels" wg kryterium: Wszystkie pola

  Lista filtrów
Wyrównaj
    Wyświetlanie 1-39 z 39
    Tytuł:
    Structural and biological characteristics of self-organising chitosan hydrogels
    Autorzy:
    Pieklarz, Katarzyna
    Tylman, Michał
    Modrzejewska, Zofia
    Galita, Grzegorz
    Majsterek, Ireneusz
    Powiązania:
    https://bibliotekanauki.pl/articles/2131528.pdf
    Data publikacji:
    2021
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    biomaterials
    chitosan
    cytotoxicity
    self-organising hydrogels
    structural properties
    tissue engineering
    Opis:
    Creating innovative methods of treatment and regeneration of damaged tissues or organs is a key challenge of the twenty-first century. The aim of this study was to determine the possibility of producing and characterising the properties of self-organising chitosan hydrogels prepared with the use of chitosan lactate/chloride and disodium hydrogen phosphate dodecahydrate as a cross-linking agent. The structure and supramolecular architecture of the biomaterials were evaluated by Fourier-transform infrared spectroscopy and polarised optical microscopy. Biological studies assessed cytotoxicity by contact with a human colon adenocarcinoma cell line. The colourimetric resazurin assay showed that the obtained chitosan hydrogels are non-cytotoxic materials. Thus, self-organising biomaterials hold great promise for application in tissue engineering.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2021, 26; 191-199
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synthesis and potential cytotoxicity evaluation of carboxymethyl chitosan hydrogels
    Autorzy:
    Kłosiński, Karol K.
    Girek, Małgorzata K.
    Wach, Radosław A.
    Czechowska-Biskup, Renata
    Arkuszewski, Piotr T.
    Szymański, Paweł B
    Pasieka, Zbigniew
    Powiązania:
    https://bibliotekanauki.pl/articles/1034588.pdf
    Data publikacji:
    2017
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    PEGDA
    XTT
    carboxymethyl chitosan
    cytotoxicity
    hydrogel
    radiation crosslinking
    Opis:
    The aim of the research was to employ radiation to produce flexible carboxymethyl chitosan (CMCS) based hydrogels of uniform structure to characterise their swelling properties and cytocompatibility for potential applications as hydrogel wound dressings. CMCS in aqueous solution was irradiated with an electron beam in the presence of a poly(ethylene glycol) diacrylate (PEGDA) macromonomer as a crosslinker, at 12 different compositions, i.e. 3–20% CMCS, 3 and 5% PEGDA. The obtained hydrogels were subjected to sol–gel analysis. The amount of insoluble fraction (up to 100%) rose with an increase in the PEGDA/polysaccharide ratio. Moreover, the equilibrium degree of swelling, ca. 15 to 200 g of water per g of gel, which was higher for lower content of crosslinker, decreased with the delivered dose, which was associated with an increase in crosslinking density. The in vitro XTT cell viability assay (murine fibroblasts, L929 cell line) showed no significant cytotoxicity of CMCS gels.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2017, 22; 82-96
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Chitosan hydrogels modified with silk, graphene oxide or reduced graphene oxide
    Autorzy:
    Szaraniec, Barbara
    Boruchowski, Marcin
    Gryń, Karol
    Chłopek, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/1844967.pdf
    Data publikacji:
    2020
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    hydrogels
    nanocomposites
    chitosan
    hydrożele
    nanokompozyty
    Źródło:
    Engineering of Biomaterials; 2020, 23, 158 spec. iss.; 44
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Chitosan hydrogels modified with silk, graphene oxide or reduced graphene oxide
    Autorzy:
    Szaraniec, Barbara
    Boruchowski, Marcin
    Gryń, Karol
    Chłopek, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/1844881.pdf
    Data publikacji:
    2020
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    hydrogels
    nanocomposites
    chitosan
    hydrożele
    nanokompozyty
    chitozan
    Źródło:
    Engineering of Biomaterials; 2020, 23, 158 spec. iss.; 44
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synthesis of chitosan and carboxymethyl chitosan hydrogels by electron beam irradiation
    Autorzy:
    Czechowska-Biskup, Renata
    Wach, Radosław
    Stojek, Piotr
    Kamińska, Martyna
    Rosiak, Janusz M.
    Ulański, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/1034681.pdf
    Data publikacji:
    2016
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    PEGDA
    carboxymethyl chitosan
    chitosan
    hydrogel
    radiation crosslinking
    Opis:
    Solutions of chitosan (CS) and carboxymethyl chitosan (CMCS) were subjected to irradiation by electron beam in presence of a crosslinking agent (poly(ethylene glycol) diacrylate - PEGDA) in order to produce carboxymethyl chitosan- and chitosan-based hydrogels. PEGDA macromonomer itself undergoes simultaneous polymerization and crosslinking either in neutral water or in acidic medium. Acidic solutions of chitosan of 0.5, 1 and 2% can be effectively crosslinked with PEGDA to form a gel. Although CMCS undergoes radiation-initiated crosslinking only at high concentration in water (over 10%), the presence of PEGDA in solution facilitated hydrogel formation even at lower concentration of CMCS. Formation of CS and CMCS hydrogels required irradiation doses lower than those needed for sterilization, i.e. 25 kGy, in some cases even as low as 200 Gy. Sol-gel analysis revealed relatively high gel fraction of obtained hydrogels, up to 80%, and good swelling ability. Both parameters can be easily controlled by composition of the initial solution and irradiation dose. Possible mechanisms of crosslinking reactions were proposed, involving addition of the polysaccharide macroradicals to a terminal double bond of PEGDA.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2016, 21; 27-45
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Fabrication and characterization of graphene-loaded chitosan hydrogels with cross-linking gradient
    Autorzy:
    Kosowska, K.
    Domalik-Pyzik, P.
    Chłopek, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/285566.pdf
    Data publikacji:
    2018
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    hydrogels
    chitosan
    nanocomposites
    Źródło:
    Engineering of Biomaterials; 2018, 21, 148; 40
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Preparation and characterization of a new generation of chitosan hydrogels containing pyrimidine ribonucleotides
    Autorzy:
    Pieklarz, Katarzyna
    Tylman, Michał
    Modrzejewska, Zofia
    Powiązania:
    https://bibliotekanauki.pl/articles/1034023.pdf
    Data publikacji:
    2020
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    biomaterial
    chitosan
    hydrogel
    neural tissue regeneration
    Opis:
    Damage to the nervous system, in particular spinal cord injuries, is a burden for the patient and is usually the cause of irreversible disability. The progress observed in the last decade in the fields of biology, biomaterial engineering and neurosurgery has created new treatment solutions while preventing further neurodegenerative processes. The most important research is focused on the implementation of polymer structures in clinical practice, especially chitosan hydrogels, which are the scaffolds for regenerating axons. This article presents a new generation of biomaterials that have the ability to gel in response to temperature changes; they are intended for injectable scaffolds for nerve cell cultures. Two types of hydrogels were prepared based on chitosan lactate and chitosan chloride using uridine 5’-monophosphate disodium salt. The structure of the systems was observed under a scanning electron microscope and examined using Fourier transform infrared spectroscopy. In addition, thermal properties were tested using differential scanning calorimetry.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2020, 25; 192-200
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Characteristics of physicochemical and rheological properties of chitosan hydrogels based on selected hydroxyacids
    Autorzy:
    Zavyalova, Olga
    Gajewska, Sandra
    Dąbrowska-Wisłocka, Dominika
    Sionkowska, Alina
    Powiązania:
    https://bibliotekanauki.pl/articles/1844766.pdf
    Data publikacji:
    2021
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Źródło:
    Engineering of Biomaterials; 2021, 24, 163; 92
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Acceleration of gelation and promotion of mineralization of chitosan hydrogels by alkaline phosphatase
    Autorzy:
    Douglas, T. E. L.
    Skwarczyńska, A.
    Modrzejewska, Z.
    Balcaen, L.
    Schaubroeck, D.
    Lycke, S.
    Vanhaecke, F.
    Vandenabeele, P.
    Dubruel, P.
    Jansen, J. A.
    Leeuwenburgh, S. C. G.
    Powiązania:
    https://bibliotekanauki.pl/articles/284363.pdf
    Data publikacji:
    2012
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    chitosan
    thermosensitivity
    composite
    mineralization
    Opis:
    Thermosensitive chitosan hydrogels containing sodium beta-glycerophosphate (ß-GP), whose gelation is induced by increasing temperature to body temperature, were functionalized by incorporation of Alkaline Phosphatase (ALP), an enzyme involved in mineralization of bone. ALP incorporation led to acceleration of gelation upon increase of temperature for four different chitosan preparations of differing molecular weight, as demonstrated by rheometric time sweeps at 37°C. Hydrogels containing ALP were subsequently incubated in calcium glycerophosphate (Ca-GP) solution to induce their mineralization with calcium phosphate (CaP) in order to improve their suitability as materials for bone replacement. Incorporated ALP retained its bioactivity and induced formation of CaP mineral, as confirmed by SEM, FTIR, Raman spectroscopy, XRD, ICP-OES, and increases in dry mass percentage, which rose with increasing ALP concentration and incubation time in Ca-GP solution. The results demonstrate that ALP accelerates formation of thermosensitive chitosan/ß-GP hydrogels and induces their mineralization with CaP, which paves the way for applications as injectable bone replacement materials.
    Źródło:
    Engineering of Biomaterials; 2012, 15, no. 116-117 spec. iss.; 135-136
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Characterization of graphene oxide-loaded chitosan hydrogels and their application for 3D printing
    Autorzy:
    Domalik-Pyzik, P.
    Chłopek, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/286115.pdf
    Data publikacji:
    2017
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    hydrogels
    graphene
    chitosan
    Źródło:
    Engineering of Biomaterials; 2017, 20, no. 143 spec. iss.; 83
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Characteristics of physicochemical and rheological properties of chitosan hydrogels based on selected hydroxy acids
    Autorzy:
    Zavyalova, Olga
    Gajewska, Sandra
    Dąbrowska-Wisłocka, Dominika
    Sionkowska, Alina
    Powiązania:
    https://bibliotekanauki.pl/articles/2058389.pdf
    Data publikacji:
    2021
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    chitosan
    lactobionic acid
    mandelic acid
    rheology
    FTIR spectra
    chitozan
    reologia
    hydrożele
    Opis:
    Chitosan is a natural cationic polymer that dissolves in an acidic environment and forms gels. Its properties depend on the degree of deacetylation and molecular weight. It is a bioactive compound with antibacterial and film-forming properties that allow to increase the regenerative capacity of the skin. Moreover, it is biodegradable, biocompatible, non-toxic, and stable. In this research, chitosan was combined with mandelic and lactobionic acids which are characterized by biological activity and low toxicity. This combination not only has a positive effect on the chitosan solubility, but it also allows to obtain new biomaterials whose positive features of the base ingredients are enhanced by their synergistic effect. The obtained hydrogels were assessed regarding the interaction of chitosan and hydroxy acid molecules, and the stability of the resulting structures was examined. The research was performed by using rheological methods and IR spectroscopy. Chitosan hydrogels made with mandelic acid are characterized by higher viscosity values, as compared to hydrogels containing lactobionic acid. The samples of the obtained hydrogels stored for 7 days showed no signs of degradation and their viscosity values were constantly increasing, which proves the ongoing process of creating new bonds between hydroxy acid molecules and chitosan chains. After this time, the hydrogels with mandelic acid revealed higher viscosity values in comparison to hydrogels made with lactobionic acid. Based on the obtained IR spectra, the shifts of the characteristic chitosan bands as a result of interaction with the tested hydroxy acids were analyzed.
    Źródło:
    Engineering of Biomaterials; 2021, 24, 161; 2--7
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Application of texture profile analysis to investigate the mechanical properties of thermosensitive injectable chitosan hydrogels
    Autorzy:
    Owczarz, Piotr
    Rył, Anna
    Wichłacz, Żaneta
    Powiązania:
    https://bibliotekanauki.pl/articles/1034254.pdf
    Data publikacji:
    2019
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    TPA
    chitosan
    hydrogels
    injectable scaffolds
    mechanical properties
    Opis:
    In this paper, the mechanical properties of hybrid chitosan hydrogels were investigated using the texture profile analysis test. Scaffolds obtained from a polysaccharide of various molecular weights were studied, which, with the addition of glycerophosphate salt, formed a three-dimensional structure in vivo. The obtained systems were also enriched with collagen and calcium carbonate to improve the mechanical properties. The determined texture parameter values indicate that the mechanical properties of the hybrid hydrogel depend on the molecular weight of the polymer, the type of solvent and, the pH-neutralizing substance, as well as the type and concentration of the filler. Moreover, in some cases the TPA test was the only way to evaluate the mechanical properties of the obtained hydrogels due to the inability to determine the Young's modulus. Consequently, the texture analysis test is a valuable tool for selecting solutions depending on the intended application of the scaffolds.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2019, 24; 151-163
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Enrichment of thermosensitive chitosan hydrogels with glycerol and alkaline phosphatase for bone tissue engineering applications
    Autorzy:
    Douglas, T. E. L.
    Krok-Borkowicz, M.
    Macuda, A.
    Pietryga, K.
    Pamuła, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/306906.pdf
    Data publikacji:
    2016
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    biomateriały
    kompozyty
    mineralizacja
    hydrożel
    biomaterials
    composites
    mineralization
    hydrogels
    Opis:
    Thermosensitive injectable chitosan hydrogels can be formed by neutralization of acidic chitosan solutions with sodium betaglycerophosphate (Na-β-GP) coupled with increasing temperature to body temperature. Such hydrogels have been considered for applications in bone regeneration. In this study, chitosan hydrogels were enriched with glycerol and the enzyme alkaline phosphatase (ALP) with a view to improving their suitability as materials for bone tissue engineering. Mineral formation was confirmed by infrared spectroscopy (FTIR) and increases in the mass fraction of the hydrogel not consisting of water. Incorporation of ALP in hydrogels followed by incubation in a solution containing calcium ions and glycerophosphate, a substrate for ALP, led to formation of calcium phosphate within the hydrogel. MG-63 osteoblast-like cells were cultivated in eluates from hydrogels containing ALP and without ALP at different dilutions and directly on the hydrogel samples. Hydrogels containing ALP exhibited superior cytocompatibility to ALP-free hydrogels. These results pave the way for the use of glycerol- and ALP-enriched hydrogels in bone regeneration.
    Źródło:
    Acta of Bioengineering and Biomechanics; 2016, 18, 2; 51-57
    1509-409X
    2450-6303
    Pojawia się w:
    Acta of Bioengineering and Biomechanics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Structural characteristics of thermosensitive chitosan glutaminate hydrogels
    Autorzy:
    Modrzejewska, Zofia
    Nawrotek, Katarzyna
    Zarzycki, R
    Douglas, Timothz
    Powiązania:
    https://bibliotekanauki.pl/articles/1035319.pdf
    Data publikacji:
    2013
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    chitosan
    hydrogel
    natural polymer
    structural properties
    Opis:
    Hydrogels that possess the ability of gelling in response to changes in the local environment, such as pH or temperature, have been examined extensively recently. In this paper the properties of thermosensitive chitosan hydrogels prepared with the use of chitosan glutaminate and -glycerophosphate are presented. The sol/gel transition point was determined based on the rheological properties. The structure of gels was observed under the Scanning Electron Microscopy (SEM) and was investigated by thermogravimetric (TG) and differential themogravimetric (DTG) analy¬sis and infrared (IR) spectroscopy. The crystallinity of gel structure was determined by X-ray Diffraction analysis (XRD).
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2013, 18, 18; 93-105
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Wpływ promieniowania mikrofalowego oraz UV na właściwości hydrożeli chitozanowych
    Influence of microwave and UV radiation on properties of chitosan hydrogels
    Autorzy:
    Bialik-Wąs, K.
    Kudłacik, S.
    Drabczyk, A.
    Tyliszczak, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/101311.pdf
    Data publikacji:
    2016
    Wydawca:
    Polska Akademia Nauk. Stowarzyszenie Infrastruktura i Ekologia Terenów Wiejskich PAN
    Tematy:
    hydrożele
    chitozan
    Beetosan
    promieniowanie UV
    promieniowanie mikrofalowe
    hydrogels
    chitosan
    UV radiation
    microwave radiation
    Opis:
    W prezentowanym artykule porównano wpływ promieniowania mikrofalowego oraz UV na przebieg reakcji sieciowania hydrożeli chitozanowych. Syntezy prowadzono zarówno w oparciu o chitozan komercyjny, jak i Beetosan - chitozan pochodzący z pszczół z osypu zimowego oraz dla układów mieszanych chitozan - Beetosan. Otrzymane materiały hydrożelowe zostały poddane badaniom zdolności pęcznienia i badaniom inkubacyjnym w wodzie destylowanej oraz symulowanych płynach ustrojowych. Ponadto, dla wybranych układów określono morfologię powierzchni przy użyciu skaningowego mikroskopu elektronowego. Wyznaczono również kąty zwilżania θ metodą geometryczną poprzez naniesienie kropli cieczy na powierzchnię badanego materiału.
    In this paper, the impact on microwave radiation and UV cross-linking of the course of reaction of obtaining chitosan hydrogels was presented. The synthesis were conducted using either commercial chitosan and Beetosan - chitosan derived from naturally died honeybees as well as using mixed systems containing both chitosan and Beetosan. The swelling capacity of obtained hydrogel materials as well as their tendency to degradation in distilled water and simulated body fluid have been tested. Moreover, morphology of the surface of selected samples using scanning electron microscope was characterized. Furthermore, the contact angles (θ) of attained materials were defined using geometrical method by applying a drop of liquid on the surface of the tested material.
    Źródło:
    Infrastruktura i Ekologia Terenów Wiejskich; 2016, II/2; 605-614
    1732-5587
    Pojawia się w:
    Infrastruktura i Ekologia Terenów Wiejskich
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synthesis of bees’ chitosan based hydrogels containing Aloe vera
    Autorzy:
    Kudłacik-Kramarczyk, S.
    Drabczyk, A.
    Tyliszczak, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/101614.pdf
    Data publikacji:
    2017
    Wydawca:
    Polska Akademia Nauk. Stowarzyszenie Infrastruktura i Ekologia Terenów Wiejskich PAN
    Tematy:
    beetosan
    chitosan
    hydrogels
    Aloe vera
    bees
    waste management
    Opis:
    Chitosan based hydrogels due to their specific properties and structure belong to the group of materials widely used in medicine. They are used as drug carriers with controlled release of active substances and in the preparation of innovative wound dressings. The main aim of the conducted research was the choice of the most favorable parameters for carrying the cross-linking reaction by means of UV radiation and microwaves. Subsequently, an adequate composition of the mixture containing chitosan and gelatin for further modification of such prepared the polymer matrix with Aloe vera extract was selected. Subsequently, an impact of introduction of Aloe vera extract into hydrogel on its physicochemical properties and structure was determined. The scope of the research included the measurement of swelling abilities of hydrogels in distilled water and selected simulated body fluids as well as incubation studies aimed at determination of tendency of prepared materials to degradation in previously mentioned fluids and their compatibility in relation to such environments. In order to characterize the chemical structure of the polymers and impact of incubation on this structure spectroscopic analysis was performed. Microscopic analysis was used to define the surface morphology of the hydrogels. Moreover, materials containing Aloe vera extract were subjected to the studies of release of additive from hydrogel matrix. Research was conducted both in acid and alkaline environment.
    Źródło:
    Infrastruktura i Ekologia Terenów Wiejskich; 2017, IV/2; 1687-1698
    1732-5587
    Pojawia się w:
    Infrastruktura i Ekologia Terenów Wiejskich
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Wpływ substancji czynnych na własności reologiczne hydrożeli chitozanowych w pobliżu granicy przejścia fazowego zol-żel
    Influence of active substances on rheological properties of chitosan hydrogels near sol-gel phase transition
    Autorzy:
    Owczarz, P.
    Modrzejewska, Z.
    Powiązania:
    https://bibliotekanauki.pl/articles/2071912.pdf
    Data publikacji:
    2012
    Wydawca:
    Stowarzyszenie Inżynierów i Techników Mechaników Polskich
    Tematy:
    chitozan
    hydrożele
    reologia hydrożeli
    matryce polimerowe
    chitosan
    hydrogel
    rheology of hydrogels
    polymeric network
    Opis:
    W pracy przedstawiono wyniki badań Teologicznych hydrożeli chitozanowych tworzących matrycę polimerową dla substancji czynnych. Jako substancje czynne stosowano albuminę wołową oraz wankomycynę. Inhibitorem przejścia fazowego zol-żel była zmiana temperatury roztworu. Wyznaczone własności reologiczne oraz krzywe temperaturowe roztworów wykazały, że w przypadku albuminy otrzymany roztwór zachowuje podobne własności jak wyjściowy roztwór chitozanu. W przypadku wankomycyny zainicjowany zmianą temperatury proces żelowania prowadzi do wytworzenia nieodwracalnej struktury.
    Rheological properties of chitosan hydrogels forming polymeric network for active substances are presented in the paper. Bovine serum albumin and vancomycin were used as active substances. A change in solution tem-perature acted as an inhibitor of sol-gel phase transition. The determined rheological properties and temperature curves of solutions showed properties similar to those of initial chitosan solution. In case of vancomycin the gelation process initiated by a temperature change led to the formation of irreversible structure.
    Źródło:
    Inżynieria i Aparatura Chemiczna; 2012, 6; 364-365
    0368-0827
    Pojawia się w:
    Inżynieria i Aparatura Chemiczna
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synthesis and characterization of novel chitosan nanocomposite hydrogels for drug delivery and bone tissue engineering
    Autorzy:
    Pazdan, K.
    Pielichowska, K.
    Chłopek, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/285119.pdf
    Data publikacji:
    2013
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    nanocomposites
    tissue engineering
    hydrogels
    Opis:
    Biodegradable materials for drug delivery and bone tissue engineering are currently intensively developing and improving, but there are still a lot of problems to solve related with bioactivity, biocompatibility, release profile etc. Osteosarcoma is an aggressive malignant neoplasm arising from primitive transformed cells of mesenchymal origin that exhibit osteoblastic differentiation and produce malignant osteoid. It is the most common histological form of primary bone cancer [1,2]. Treatment is most destinations and made up for: intensive multidrug short induction chemotherapy, amputation or tumor resection within the limits of normal tissue and in the last phase again chemotherapy. This kind of neoplasm is most recently detected in young male till 25 age, therefore improving methods of treatment is so important. Chitosan is a natural-based polymer obtained by alkaline deacetylation of chitin received from powdered shrimp shells was purchased from Acros Organics. Its main advantages are non-toxic, non-immunogenic, non-carcinogenic degradation products, biocompatible, bioactive and biodegradable. These properties cause chitosan a very good candidate for novel hydrogel drug delivery systems. Chitosan easily forms hydrogel particles and entraps biomolecules through a number of mechanisms, including chemical crosslinking, ionic crosslinking, and ionic complexation [3,4]. A possible alternative of chitosan by the chemical modification also has been useful for the association of bioactive molecules to polymer and controlling the drug release profile. There are few methods of modification, or example.: copolimerization, grafting, chemical and ionic crosslinking, polyelectrolyte complexes, etc [5]. Previous studies demonstrated that chitosan could promote the proliferation and osteogenesis but only with moderate swelling ratio of composite, too high ability of entrapment water solutions are not recommended. There are a lot of advantages in chitosan properties that can be used in research work to obtain the material of the best expected properties. Laponite® (LA) is a plate-like synthetic clay hectoritetype belongs to a family of phyllosolicates type 2:1 [6]. Its structure represent empirical formula: Na0.7+[Si8Mg5.5Li0.3 O20(OH)4]0.7-. The plates size is about 25 nm x 0,92 nm. LA has a large surface area, anionic surface charges and exchangeable Na+ cations in hydrated interlayers. Presence of sodium cations causes better adsorption properties for cationic drug molecules. Moreover, the exfoliated LA particles may act as multifunctional crosslinkers in forming the nanocomposite hydrogels, and the polymer chains were anchored to the particles and entangled to form a network [7]. Used synthetic clay has got the same type structure and but better sorption properties to montmorillonite but it has got serious advantage - as a synthetic compound shows low heavy metal content. The initial results indicate that the incorporation of clay improved the swelling behavior in contrast to the pure chitosan beads. There also had been revealed significant disproportion of viscosity received hydrogels according to different type of LA or different concentration. Increasing content causes telling rise of viscosity, especially reported in higher content of used crosslinker. The aim of research is to develop a bioactive system biopolymer/layered silicate intelligent nanocomposite based on chitosan and synthetic clay by a cross-linking reaction using sodium tripolyphosphate as the gel factor. The resultant composite were characterized by Fourier transform infrared spectroscopy, scanning electronic microscope and X-ray diffraction analysis. The bioactivity in physiological pH solution (SBF pH=7.40) [8], drug encapsulation efficiency and controlled release behaviour were also investigated by using the model drug to reveal the effects of introduced LA.
    Źródło:
    Engineering of Biomaterials; 2013, 16, no. 122-123 spec. iss.; 1-2
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Influence of shear direction on gelation ability of colloidal chitosan solutions
    Autorzy:
    Rył, Anna
    Owczarz, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/185096.pdf
    Data publikacji:
    2019
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    sol-gel phase transition
    chitosan hydrogels
    rheometry measurements
    oscillatory shear
    rotational shear
    hydrożel chitozanowy
    pomiar reometrii
    ścinanie oscylacyjne
    ścinanie rotacyjne
    Opis:
    This paper discusses the influence of the direction of applied deformation on the ability to gelation of thermosensitive chitosan hydrogels. The application of the shear rate equal in value to the classically performed oscillatory measurements leads to significantly different shapes of experimental curves. It was found that the type of mechanically applied deformation has a significant impact on the gelation ability of colloidal chitosan solutions and conditions of sol-gel phase transition. Simple shear leads to a phase transition at a lower temperature or in a shorter time compared to oscillatory tests. Moreover, based on the final values of dynamic viscosity in rotational measurements, it was found that stronger crosslinking of the polymer structure was observed.
    Źródło:
    Chemical and Process Engineering; 2019, 40, 2; 207--212
    0208-6425
    2300-1925
    Pojawia się w:
    Chemical and Process Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Double crosslinking of chitosan/vanillin hydrogels as a basis for mechanically strong gradient scaffolds for tissue engineering
    Autorzy:
    Hunger, Martyna
    Domalik-Pyzik, Patrycja
    Reczyńska, Katarzyna
    Chłopek, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/1844976.pdf
    Data publikacji:
    2020
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    hydrogel
    chitosan
    vanillin
    tripolyphosphate
    tissue engineering
    Opis:
    Polysaccharides, such as chitosan (CS), are widely used in many biomedical applications. However, they require crosslinking agents to achieve chemical stability and appropriate mechanical properties. In this work, chitosan-based hydrogels were crosslinked using vanillin and/or sodium tripolyphosphate, as chemical and physical crosslinking agents, respectively. Microstructural (digital microscope, SEM), structural (FTIR-ATR), mechanical (static compression test), and in vitro biological (chemical stability and swelling ratio in PBS, cytotoxicity) properties of the obtained materials were evaluated to assess materials potential as biomedical scaffolds. The optimal ratio of vanillin to chitosan (DD = 89%) to crosslink the polymer was found to be 1.2:1. Moreover, the double crosslinking with vanillin caused a two-time increase in the compression strength of the samples and led to the slower biodegradability. Cytotoxicity studies showed that the cells prefer double vanillin crosslinked hydrogels over those treated with TPP. Further studies, such as bioactivity are required to determine the specific functionality of the hydrogels and the specific tissue which may be treated with the tested materials. The optimal material was chosen to the next step of the study, which may be obtaining composite hydrogels with hydroxyapatite and/or graphene oxide to tailor or improve properties towards specific tissue regeneration.
    Źródło:
    Engineering of Biomaterials; 2020, 23, 155; 2-11
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Chitosan/poly(vinyl alcohol) hydrogels as controlled drug delivery systems
    Autorzy:
    Kocemba, Aleksandra
    Mucha, Maria
    Powiązania:
    https://bibliotekanauki.pl/articles/1034608.pdf
    Data publikacji:
    2017
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    chitosan/PVA hydrogel
    gentamicin
    glutaraldehyde
    release kinetics
    swelling
    Opis:
    In order to achieve hydrogel and drug release profiles, a comprehensive knowledge of the types, properties and syntheses of hydrogel polymer networks are needed. For this reason, a natural biopolymer hydrogel based on chitosan was described. Chitosan has many advantages, which meet the requirements necessary for the preparation of medical materials; for example, wound dressings. This article focused on the biomedical use of a chitosan hydrogel: chitosan–poly(vinyl alcohol) (PVA). The method of preparation of hydrogels containing a drug as an active wound dressing was described. To obtain a hydrogel dressing to be applied in patients with burns or difficult curative wounds, gentamicin (an aminoglycoside antibiotic) was used as a medicament. The effect of the PVA concentration in hydrogels on the release rate of the antibiotic was examined. For this, the crosslinking agent of the hydrogel, glutaraldehyde, was used. The release process of gentamicin was described by using an equation of first order kinetics.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2017, 22; 97-105
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Cytotoxicity of chitosan based thermo-sensitive hydrogels intended for nervous tissue engineering
    Autorzy:
    Nawrotek, Katarzyna
    Modrzejewska, Zofia
    Paluch, Danuta
    Zarzycki, Roman
    Rusak, Agnieszka
    Powiązania:
    https://bibliotekanauki.pl/articles/1034899.pdf
    Data publikacji:
    2015
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    Chitosan
    biomaterial
    hydrogel
    nervous tissue regeneration
    Opis:
    The damage to the central nervous system is one of the most difficult cases of trauma to treat. Over the last few years, increasing attention has been focused on the development of strategies based on biomaterials for regeneration and repair of the spinal cord injury. In particular, materials in the form of hydrogels based on chitosan are being actively investigated due to their intrinsic properties that are favorable in spinal cord tissue regeneration. The purpose of this study was to develop a thermo-gelling chitosan solution that will be prepared with the use of acids that naturally occur in the human nervous tissue. For this purpose, two types of chitosan gels were prepared based on chitosan glutamate and chitosan lactate. In order to reduce toxic action of the system obtained gels were conditioned in distilled water with pH 5.00. The changes in the structures of systems obtained were determined with the use of FTIR method. Biocompatibility was primarily evaluated through cytotoxicity testing by MTT assay with respect to mouse fibroblast cells.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2015, 20; 222-235
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Mechanical properties of hydrogels in a chitosan/ silk/graphene system
    Autorzy:
    Boruchowski, Marcin
    Gryń, Karol
    Szaraniec, Barbara
    Chłopek, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/1844939.pdf
    Data publikacji:
    2020
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    hydrogels
    chitosan
    mechanical properties
    hydrożele
    właściwości mechaniczne
    Źródło:
    Engineering of Biomaterials; 2020, 23, 158 spec. iss.; 45
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Mechanical properties of hydrogels in a chitosan/ silk/graphene system
    Autorzy:
    Boruchowski, Marcin
    Gryń, Karol
    Szaraniec, Barbara
    Chłopek, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/1844879.pdf
    Data publikacji:
    2020
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    hydrogels
    chitosan
    mechanical properties
    hydrożele
    chitozan
    właściwości mechaniczne
    Źródło:
    Engineering of Biomaterials; 2020, 23, 158 spec. iss.; 45
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The influence of substrate composition on the physicochemical properties of hydrogels with chitosan
    Autorzy:
    Szcześniak, Maria
    Grimling, Bożena
    Meler, Jan
    Pluta, Janusz
    Powiązania:
    https://bibliotekanauki.pl/articles/1034687.pdf
    Data publikacji:
    2016
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    Carbopl 934P
    PVP
    chitosane
    hydrogels
    pharmaceutical availability
    rheological parameters
    Opis:
    The aim of the study was to evaluate the effect of Carbopol 934 P and PVP K 90 on the rheological properties of chitosan gels. Hydrogels were prepared with hydrocortisone containing chitosan, Carbopl 934P, PVP, propylene glycol-1,2 or polyethyleneglycol 400 and glycerol. Addition of polymers had positive influence on the dispersion of hydrogels. The studied gels have thixotropic properties, their viscosity increases with the increase of the concentration of polymers. Increase of the content of polyvinylpyrrolidone K 90 and Carbopol 934 P increases the consistence, gels are more firm and cohesive. Gels with 5 % chitosane, 15% polyvinylpyrrolidone K 90 and Carbopol 934 P in the presence of additives have prolonged half release period of hydrocortisone.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2016, 21; 187-191
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Application of chitosan in the formulation of hydrogels applied on skin
    Autorzy:
    Meler, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/1035198.pdf
    Data publikacji:
    2013
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    chitosan
    hydrocortisone
    hydrogels
    pharmaceutical availability
    Opis:
    These studies concerned the effect of composition on the substrate physicochemical parameters of hydrogels for use on skin. Hydrogels containing 1% of hydrocortisone and 1% of chitosan addition was made on the basis of methylcellulose, sodium carboxymethylcellulose and Carbopol 934 P. The release proceeds according to first-order kinetics. Depending on the type and composition of the polymer gels were obtained with various pharmaceutical availability of hydrocortisone. Addition of 1% chitosan affects the acceleration of the release in any given case.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2013, 18, 18; 181-186
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Development of thermosensitive hydrogels of chitosan, sodium and magnesium glycerophosphate for bone regeneration applications
    Autorzy:
    Liškova, J.
    Bačakova, L.
    Skwarczyńska, A.
    Musiał, O.
    Bliznuk, V.
    De Schampelhaere, K.
    Modrzejewska, Z.
    Douglas, T. E. L.
    Powiązania:
    https://bibliotekanauki.pl/articles/284238.pdf
    Data publikacji:
    2017
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    hydrogels
    bone regeneration
    chitosan
    Źródło:
    Engineering of Biomaterials; 2017, 20, no. 143 spec. iss.; 44
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The formation of hydrogels based on chitosan and its water-soluble derivatives
    Autorzy:
    Il’ina, Alla V.
    Shagdarova, Balzhima Ts.
    Lunkov, Alexey P.
    Varlamov, Valery P.
    Powiązania:
    https://bibliotekanauki.pl/articles/1034059.pdf
    Data publikacji:
    2020
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    chitosan
    crosslinking agent
    gelation
    hydrogels
    quaternized chitosan
    succinyl chitosan
    Opis:
    This review considers articles on the formation of hydrogels based on chitosan as well as succinylated and quaternized chitosan derivatives. They are synthesized using low toxicity reagents, under ordinary conditions (low production costs). Chitosan derivatives are soluble in an extended range of pH values and characterized by mucoadhesiveness, bioavailability and biodegradability, which extends the potential of their medical applications. One of the most important properties of chitosan and its derivatives is the ability to form hydrogels. Depending on the nature of the bonds that occur during formation, hydrogels are divided into chemically or physically crosslinked, or a mixture of the two. Chemically crosslinked gels have covalent bonds, while physically crosslinked gels are formed by noncovalent interactions, for example, ionic. Mixed hydrogels have both types of crosslinking.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2020, 25; 5-15
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The influence of selected polymers on the rheological properties of hydrogels with chitosan applied on the skin
    Autorzy:
    Szcześniak, Maria
    Grimling, Bożena
    Meler, Jan
    Karolewicz, Bożena
    Powiązania:
    https://bibliotekanauki.pl/articles/1034591.pdf
    Data publikacji:
    2017
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    chitosan
    hydrogels
    pharmaceutical availability
    rheological parameters
    Opis:
    The aim of the study was to evaluate the effect of methylcellulose and carboxymethylcellulose on the rheological properties of hydrogels applied to skin on chitosan in the presence of the additives propylene glycol and glycerol. Rheological studies showed that the tested gels are non-newtonian systems, and have thixotropic properties. Substrates made of methylcellulose and chitosan are characterised by higher shear values than those obtained with carboxymethylcellulose. The addition of polymers had a positive influence on the dispersion of hydrogels, and the addition of excipients increased firmness, consistency and cohesiveness of the gels. Larger increases were observed with the addition of 10% of glycol propylene and glycerol contents for methylcellulose and of 20% of carboxymethylcellulose.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2017, 22; 201-206
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Rheological aspects of the flow of thermosensitive chitosan systems during injection application
    Autorzy:
    Rył, Anna
    Owczarz, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/1034161.pdf
    Data publikacji:
    2020
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    chitosan scaffolds
    injectability
    thermosensitive hydrogels
    Opis:
    The aim of this paper was to conduct preliminary instrumental tests to determine the possibility of injection applications for thermosensitive chitosan systems, including injection needles and application conditions. Among the many biomedical and pharmaceutical applications of chitosan, the minimally invasive thermosensitive scaffolds that form in vivo are an interesting solution. Despite many studies on colloidal chitosan systems undergoing sol-gel phase transition, almost no studies have examined their injectability. It has been stated that the use of acetic acid as a solvent reduces the forces needed for injection. Moreover, the key impact of injection temperature was determined. Storing the medium at room temperature before the injectability test led to a decrease in the value of forces needed for injection. The obtained results are discussed based on the change of the rheological properties of the chitosan hydrogels.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2020, 25; 201-209
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Application of chitosan in the formulation of dermatological hydrogels prepared on the basis of macromolecular compounds
    Autorzy:
    Szcześniak, Maria
    Grimling, Bożena
    Meler, Jan
    Karolewicz, Bożena
    Powiązania:
    https://bibliotekanauki.pl/articles/1034450.pdf
    Data publikacji:
    2018
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    chitosan
    hydrogels
    rheological parameters
    Opis:
    The effect of chitosan concentration on the properties of dermatological preparations prepared with 2% methylcellulose and 10% polyvinylpyrrolidone was studied. As the levels of chitosan, propylene glycol-1,2 and glycerol increased, the hardness, consistency and cohesiveness of the hydrophilic gels increased, while the dissipation capacity decreased. Gels based on methylcellulose and chitosan, compared to formulations containing polyvinylpyrrolidone, have a higher rate of loss of volatile compounds, higher pH values for 1,2-propylene glycol formulation and higher texture parameters. The tested hydrogels have good rheological properties, allowing extrusion from the tube and spreading on the skin.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2018, 23; 179-184
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Structural research of thermosensitive chitosan-collagen gels containing alp
    Autorzy:
    Skwarczyńska, Agata
    Biniaś, Dorota
    Modrzejewska, Zofia
    Powiązania:
    https://bibliotekanauki.pl/articles/1034675.pdf
    Data publikacji:
    2016
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    alkaline phosphatase
    chitosan
    collagen
    thermosensitive hydrogels
    Opis:
    Introducing collagen, which is basic ingredient of bone tissue, into the structure of chitosan gels which are formed at the physiological body temperature, is aimed at creating the so-called biomimetic structures, i.e. close in their composition to the natural composition of bone tissue. Within the research the influence of collagen on structural properties of thermosensitive chitosan gels and the influence of ALP on structural properties of chitosan and chitosan-collagen gels was determined.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2016, 21; 176-186
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Mechanism of water diffusion into noncrosslinked and ionically crosslinked chitosan membranes
    Autorzy:
    Gierszewska-Drużyńska, Magdalena
    Ostrowska-Czubenko, Jadwiga
    Powiązania:
    https://bibliotekanauki.pl/articles/1035376.pdf
    Data publikacji:
    2012
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    alginate
    chitosan
    pH-responsive hydrogels
    swelling
    tripolyphosphate
    Opis:
    Ionically crosslinked chitosan membranes were prepared and their swelling behaviour was analysed. Low‑molecular pentasodium tripolyphosphate (TPP) and/or high‑molecular sodium alginate (NaAlg) were used as ionic crosslinkers. Dynamic swelling of noncrosslinked (Ch) as well as singly (Ch/TPP, Ch/NaAlg) and doubly (Ch/NaAlg/TPP) crosslinked chitosan membranes was performed in buffered aqueous solutions of various pH to determine the mechanism of water diffusion into these hydrogels. It was stated out that mechanism of water diffusion into studied chitosan hydrogel membranes depends both on pH of swelling solution as well as on the type of membrane (type of crosslinker). The water transport mechanism was determined to be: i) Fickian or ‘Less Fickian’ diffusion, ii) non‑Fickian diffusion (anomalous diffusion) and iii) Case II or Super Case II diffusion.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2012, 17; 63-70
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Application of chitosan in the formulation of methyl cellulose-based hydrogels
    Autorzy:
    Szcześniak, Maria
    Grimling, Bożena
    Meler, Jan
    Pluta, Janusz
    Powiązania:
    https://bibliotekanauki.pl/articles/1035190.pdf
    Data publikacji:
    2014
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    chitosan
    methylcellulose
    pharmaceutical availability
    rheological parameters
    Opis:
    The aim of this work was to study the properties of methylcellulose hydrogels with supplements containing chitosan and 1% hydrocortisone. Depending on the composition of the substrate, gels are characterised by a variety of pharmaceutical availabilities. Increasing the concentration of chitosan has an influence on increasing the viscosity, hardness, and cohesiveness of the tested gels.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2014, 19; 139-144
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Chitosan microcapsules obtained by wet method as potential carriers for active substance
    Autorzy:
    Startek, J.
    Dzierzkowska, E.
    Golańska, J.
    Stodolak-Zych, E.
    Rapacz-Kmita, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/283823.pdf
    Data publikacji:
    2018
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    hydrogels
    biomaterials
    chitosan
    Źródło:
    Engineering of Biomaterials; 2018, 21, 148; 92
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effect of chitosan on the rheological properties of hydrogels based on sodium carboxymethylcellulose
    Autorzy:
    Szcześniak, Maria
    Grimling, Bożena
    Pluta, Janusz
    Meler, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/1034876.pdf
    Data publikacji:
    2015
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    chitosan
    pharmaceutical availability
    rheological parameters
    sodium carboxymethylcellulose
    Opis:
    The aim of the study was to evaluate the effect of changing the concentrations of chitosan on the rheological properties of the obtained formulation. Hydrogels were prepared with 1% hydrocortisone containing 4% sodium carboxymethylcellulose with the addition of chitosan, propylene glycol-1,2 or polyethylene glycol 400 and glycerol or paraffin. The concentration of chitosan and excipients affects the rheological properties of gels and the pharmaceutical availability of hydrocortisone. Increasing the concentration of chitosan have influence on increasing the viscosity, hardness, and cohesiveness of the tested gels.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2015, 20; 254-259
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Physicochemical properties and cytotoxicity of hydrogels based on Beetosan® containing sage and bee pollen
    Autorzy:
    Tyliszczak, Bożena
    Drabczyk, Anna
    Kudłacik-Kramarczyk, Sonia
    Grabowska, Beata
    Kędzierska, Magdalena
    Powiązania:
    https://bibliotekanauki.pl/articles/1038565.pdf
    Data publikacji:
    2017
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    hydrogels
    cytotoxicity
    fibroblasts
    chitosan
    sage
    wettability
    Opis:
    Currently, increasing attention is being paid to issues related to environmental protection, waste management, as well as to the development of polymers with useful properties. The research presented here involved preparation of hydrogels based on Beetosan® - a chitosan derived from the multi-stage processing of dead bees. Moreover, hydrogels were additionally modified with natural substances - i.e. bee pollen and extract of Salvia officinalis (sage) that are well known for the presence of many compounds with beneficial properties from a medical point of view. Materials have been first obtained by photopolymerization. Then, their surface morphology, wettability and cytotoxicity to selected cell lines have been determined. It can be stated that such combination of Beetosan® hydrogel matrix and the mentioned additives resulted in a preparation of polymers characterized by negative impact on cancer cells. Impact of hydrogels with sage is slightly more intense due to the presence of substances such as ursalic or rosmaric acid that are characterized to have anticancer activity. Such negative impact has not been observed in case of studies using fibroblasts. Furthermore, addition of natural substances into hydrogels resulted in a more homogeneous surface and in the decrease of wettability angle of the tested polymers. It can be concluded that the use of natural-derived reagents and synthesis of polymers using these reagents (as a result of environmentally friendly photopolymerization) yields materials with interesting properties for medical purposes, with particular emphasis on antitumor activity, and without significant negative impact on fibroblasts.
    Źródło:
    Acta Biochimica Polonica; 2017, 64, 4; 709-712
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The influence of the addition of collagen on the rheological properties of chitosan chloride solutions
    Autorzy:
    Owczarz, Piotr
    Rył, Anna
    Modrzejewska, Zofia
    Dziubiński, Marek
    Powiązania:
    https://bibliotekanauki.pl/articles/1034555.pdf
    Data publikacji:
    2017
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    chitosan
    collagen
    rheology
    thermosensitive hydrogels
    viscoelastic behaviour
    Opis:
    Colloidal solutions of chitosan of crab origin with the addition of collagen obtained from cowhide were studied. Were presents the influence of collagen concentration and the method of preparing the sample on the obtained mechanical properties of the solutions and the observed phase transition temperature. Rheological measurements were performed to determine the viscoelastic properties and phase transition temperatures of these solutions. The study was conducted in the temperature range of 5–60°C with the use of classical techniques of rotational rheometry in the cone-plate measurement system. A significant influence of a collagen addition to chitosan chloride solutions on the viscoelastic properties of the systems was observed. The addition of collagen in all the cases increased the sol–gel phase transition temperature in comparison with the chitosan chloride solution containing β-glycerophosphate.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2017, 22; 176-189
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Wpływ ilości fotoinicjatora na właściwości i strukturę matrycy hydrożelowej
    Effect of the photoinitiator amount on properties and structure of the hydrogel matrix
    Autorzy:
    Kudłacik, S.
    Drabczyk, A.
    Bialik-Wąs, K.
    Tyliszczak, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/101598.pdf
    Data publikacji:
    2016
    Wydawca:
    Polska Akademia Nauk. Stowarzyszenie Infrastruktura i Ekologia Terenów Wiejskich PAN
    Tematy:
    hydrożele
    fotopolimeryzacja
    chitozan
    fotoinicjator
    absorpcja
    stopień usieciowania
    hydrogels
    photopolymerization
    chitosan
    photoinitiator
    adsorption
    degree of crosslinking
    Opis:
    W pracy przedstawiono syntezę materiałów hydrożelowych metodą fotopolimeryzacji. Zsyntezowano szereg materiałów różniących się zawartością fotoinicjatora oraz przeprowadzono badanie zdolności pęcznienia i inkubację. Wykonano pomiar kątów zwilżania i analizę spektroskopową FT-IR. Na podstawie przeprowadzonych badań potwierdzono wpływ ilości fotoinicjatora na budowę materiału polimerowego. Zsyntezowane materiały cechowały się różną strukturą usieciowania, a co za tym idzie różnymi właściwościami. Możliwość modyfikacji struktury stwarza większe możliwości w zastosowaniach tych materiałów.
    The paper presents a synthesis of the hydrogel materials by photopolymerization. A series of materials differing in the amount of photoinitiator was prepared. In these studies the ability of swelling of attained materials was determined. What is more, incubation studies were also carried out. Measurements of contact angles was conducted and a chemical structure of obtained materials was defined using FT-IR spectroscopy. On the basis of the research the impact on the amount of the photo-initiator on the structure of a polymeric material have been defined. Synthesized materials were characterized by a different degree of the cross-linking, and therefore they have different properties. Hence the conclusion that possibility of the structure modifying of the material creates more opportunities for its use.
    Źródło:
    Infrastruktura i Ekologia Terenów Wiejskich; 2016, II/2; 627-636
    1732-5587
    Pojawia się w:
    Infrastruktura i Ekologia Terenów Wiejskich
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-39 z 39

      Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies