Application of chitosan in the formulation of hydrogels applied on skin

These studies concerned the effect of composition on the substrate physicochemical parameters of hydrogels for use on skin. Hydrogels containing 1% of hydrocortisone and 1% of chitosan addition was made on the basis of methylcellulose, sodium carboxymethylcellulose and Carbopol 934 P. The release proceeds according to first-order kinetics. Depending on the type and composition of the polymer gels were obtained with various pharmaceutical availability of hydrocortisone. Addition of 1% chitosan affects the acceleration of the release in any given case.