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Wyświetlanie 16-30 z 1166
Tytuł:
ASSESSMENTS OF ANTIOXIDANT CONTENT AND THE ANTI-CARCINOGENIC EFFECT OF EXTRACTS OF SOLANUM ROSTRATUM DUNAL IN HUMAN CANCER CELLS
Autorzy:
Valadez Vega, María del Carmen
Izquierdo Vega, Jeannett Alejandra
Villagómez Ibarra, Jose Roberto
Sánchez Gutiérrez, Manuel
Madrigal Santillán, Eduardo Osiris
Morales Gonzalez, Jose Antonio
Bautista Ávila, Mirandeli
García Velasco, Laura
Powiązania:
https://bibliotekanauki.pl/articles/895384.pdf
Data publikacji:
2019-06-28
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
antioxidant
cytotoxic
Solanum rostratum
SiHa cell line
MDA cell line
Opis:
In Mexico, Solanum rostratum has been employed for the treatment of several diseases, including uterine cancer. The aim of this study was to evaluate the antioxidant and anti-carcinogenic activity of extracts of Solanum rostratum Dunal on MDA and SiHa cell lines. The methanolic, ethyl acetate, and hexane extracts of the aerial parts of Solanum rostratum were tested for phenols concentration, antioxidant activity, and anti-carcinogenic effect. The leaves extracts showed the highest content of phenols; however the flower-fruits extracts showed higher scavenging activity. On the other hand, ethyl acetate extracts exhibited the highest anti-carcinogenic effect, while methanolic extracts showed the least effect. The results of this work indicated that Solanum rostratum is a promising source of antioxidants, and the extracts exert a dose-dependent anti-carcinogenic effect on both cell lines.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 3; 493-502
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Certain protein transducing agents convert translocated proteins into cell killers
Autorzy:
Tcherniuk, Siergiej
Fiser, Anne-Laure
Derouazi, Madiha
Toussaint, Bertrand
Wang, Yan
Wojtal, Izabela
Kondo, Eisaku
Szolajska, Ewa
Chroboczek, Jadwiga
Powiązania:
https://bibliotekanauki.pl/articles/1039725.pdf
Data publikacji:
2012
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
cytotoxic protein
cell transduction
protein delivery
cell translocation
transducing peptides
Opis:
The majority of proteins are unable to translocate into the cell interior. Hence for peptide- and protein-based therapeutics a direct intracytoplasmic delivery with the aid of transducing agents is an attractive approach. We wanted to deliver to the cell interior a putatively cytotoxic protein VPg. Protein transduction was achieved in vitro with three different commercial products. However, in our hands, delivery of various control proteins without known deleterious effects, as well as of protein VPg, always induced cell death. Finally, we used a novel transducing peptide Wr-T, which was not toxic to cultured cells, even in a quite large range of concentrations. Most importantly, control protein delivered to cells in culture did not display any toxicity while VPg protein exerted a strong cytotoxic effect. These data show that results obtained with cell-penetrating agents should be interpreted with caution.
Źródło:
Acta Biochimica Polonica; 2012, 59, 3; 433-439
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Skin of sailor: cutis rhomboidalis nuchae, actinic keratosis, squamous cell carcinoma and basal cell carcinoma. Case report
Autorzy:
Abdulaziz, Ahmad
Brzeziński, Piotr
Chiriac, Anca
Powiązania:
https://bibliotekanauki.pl/articles/1065852.pdf
Data publikacji:
2014
Wydawca:
Medical Education
Tematy:
actinic keratosis
basal cell carcinoma
sailor
squamous cell carcinoma
ultraviolet
Opis:
Chronic exposure to environmental ultraviolet radiation (UVR) plays a key role both in photocarcinogenesis and induction of accelerated skin ageing. Sailors commonly experience a significant number of cutaneous problems, related to the exposure to environmental factors due to their working conditions. Among these factors, sun exposure is able to determine both acute and chronic skin damage, mostly linked to the effects of the ultraviolet (UV) radiation on epidermal and dermal structures. We report a case of sailor with cutis rhomboidalis nuchae, solar elastosis, actinic keratosis (AK), numerous squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) of the head and trunk.
Źródło:
OncoReview; 2014, 4, 1; A37-41
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Phenotypic characteristics of feline adipose-derived stem cells affected by cell passage number
Autorzy:
Panasophonkul, S.
Samart, P.
Kongon, K.
Sathanawongs, A.
Powiązania:
https://bibliotekanauki.pl/articles/2087880.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
adipose-derived stem cell
feline
phenotypic characteristic
cell passage number
Źródło:
Polish Journal of Veterinary Sciences; 2017, 4; 651-660
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Lead transport and localisation in Lupinus angustifolius L. root cells
Autorzy:
Balcerzak, L.
Godlewski, M.
Powiązania:
https://bibliotekanauki.pl/articles/80056.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
conference
lead transport
Lupinus angustifolius
root cell
lead nitrate
root meristem cell
transmission electron microscopy
cell organelle
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 3
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Modeling of voice data integrated traffic in 3G mobile cellular network
Autorzy:
Islam, I.
Das, J. K.
Hossain, S.
Powiązania:
https://bibliotekanauki.pl/articles/308765.pdf
Data publikacji:
2007
Wydawca:
Instytut Łączności - Państwowy Instytut Badawczy
Tematy:
3G mobile
voice data integrated service
micro cell
macro cell
satellite cell
Markovian chain and thinning scheme
Opis:
The most important feature of 3G mobile cellular network is introduction of voice data integrated service under multilayered cell environment to support overflow traffic of lower layered cells by upper ones. This paper deals with traffic model of three layered cells, i.e., micro cell, macro cell and satellite cell. Here a new call admission control is introduced for three layered cell of 3G mobile cellular network. State transition chain is designed for theoretical analysis of above mentioned traffic. Blocking probability of data call, new voice call and handover failure of voice call, probability of utilization of micro cell channel, macro cell channel and satellite cell channel are analyzed against different traffic parameters and yield logical results.
Źródło:
Journal of Telecommunications and Information Technology; 2007, 2; 103-108
1509-4553
1899-8852
Pojawia się w:
Journal of Telecommunications and Information Technology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Architecture of the exocyst complex in plant cells
Autorzy:
Kasprowicz, A.
Pihan, K.
Ochocki, M.
Kwiatkowski, W.
Wojtaszek, P.
Powiązania:
https://bibliotekanauki.pl/articles/80552.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
conference
exocytosis
plant cell
eukaryotic cell
plasma membrane
protein-protein interaction
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 3
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analiza teoretyczna uzysku energetycznego krzemowych ogniw fotowoltaicznych w warunkach solarnych Małopolski
Theoretical analysis of energy yield for silicon photovoltaic cells in solar conditions in Małopolska Region
Autorzy:
Latała, H.
Kurpaska, S.
Powiązania:
https://bibliotekanauki.pl/articles/292071.pdf
Data publikacji:
2011
Wydawca:
Polskie Towarzystwo Inżynierii Rolniczej
Tematy:
ogniwo fotowoltaiczne
ogniwo krzemowe
energetyka
photovoltaic cell
silicone cell
power engineering
Opis:
W pracy przeanalizowano teoretyczne możliwości uzysku energii elektrycznej dla panelu fotowoltaicznego wykonanego z krzemu polikrystalicznego. Obliczenia wykonano dla miesięcznych średnich wieloletnich wartości natężenia promieniowania słonecznego dostępnego w warunkach solarnych Małopolski. Do badań wybrano, dostępne na rynku i możliwe do zastosowań w gospodarstwach tego regionu, źródło o mocy 235 Wp.
The work contains an analysis of the theoretical potential of the electric energy yield for a photovoltaic panel made of polycrystalline silicon. Calculations were based on monthly multiannual average values of solar radiation intensity available in solar conditions of Małopolska Region. For their purposes, the researchers have chosen a source with a power reaching 235 Wp, which is available in the market and may be used in farms located in this region.
Źródło:
Inżynieria Rolnicza; 2011, R. 15, nr 4, 4; 183-189
1429-7264
Pojawia się w:
Inżynieria Rolnicza
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Reduced expression of E-cadherin and increased sialylation level in clear cell renal cell carcinoma
Autorzy:
Borzym-Kluczyk, Małgorzata
Radziejewska, Iwona
Cechowska-Pasko, Marzanna
Darewicz, Barbara
Powiązania:
https://bibliotekanauki.pl/articles/1038588.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
clear cell renal cell carcinoma
E-cadherin
lectins
sialyl Lewis antigens
Opis:
Cancer cells are characterized by an aberrant increase in protein N-glycosylation and by disruption of E-cadherin-mediated adherens junctions. However, the relationship between alterations in N-glycosylation process and loss of E-cadherin adhesion in cancer remains unclear. The mechanisms of altered expression of adhesive glycoproteins in cancer cells have not been fully elucidated. Thus, the aim of this study was to examine the expression of E-cadherin and sialyl Lewisa/x, NeuAcα2-3Gal, NeuAcα2-6Gal/GalNAc structures in the normal renal tissue and intermediate and cancerous tissues from patients with clear cell RCC. Moreover, we attempted to correlate the E-cadherin expression with some specific sugar residues of renal cancer tissue glycoproteins. The expression of E-cadherin was analysed using ELISA test and immunoblotting. Oligosaccharide structures and sialylation level were detected with ELISA test using specific biotinylated lectins or antibodies. A significant decrease of E-cadherin expression as well as a significant increase in sialylated oligosaccharides level in intermediate zone and renal cancer tissue in comparison to normal renal tissue are reported. Significant decrease in expression of cadherins and increase in sialylation of oligosaccharide structures in renal cancer tissue in comparison to normal renal tissue, and in renal cancer tissue in comparison to intermediate zone of renal tissue, are important for the future research concerning detection and quantification of cadherins and sialylated oligosaccharide structures in urine and cells of urinary sediment as possible non-invasive marker of early RCC.
Źródło:
Acta Biochimica Polonica; 2017, 64, 3; 465-470
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
High frequency metrology for intracardiac ablation: in-vivo results
Autorzy:
Rouane, A.
Bru, P.
Powiązania:
https://bibliotekanauki.pl/articles/221888.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
impedance matching
voltage measurement cell
current measurement cell
high frequency energy
Opis:
Cardiac Radiofrequency (RF) ablation is a commonly used clinical procedure for treating many cardiac arrhythmias. However, the efficacy of RF ablation may be limited by two factors: small ventricular lesions and impedance rise, leading to coagulum formation and desiccation of tissue. In this paper, a high frequency (HF) energy ablation system operating at 27.12 MHz based on an automated load matching system was developed. A HF energy matched probe associated to the automated impedance matching device ensures optimal transfer of the energy to the load. The aim of this study was to evaluate this energy for catheter ablation of the atrioventricular junction. In vivo studies were performed using 10 sheep to characterize the lesions created with the impedance matching system. No cardiac perforation was noted. No thrombus was observed at the catheter tip. Acute lesions ranged from 3 to 45 mm in diameter (mean šSD = 10.3š10) and from 1 to 15 mm in depth (6.7š3.9), exhibiting a close relationship between HF delivered power level and lesion size. Catheter ablation using HF current is feasible and appears effective in producing a stable AV block when applied at the AV junction and large myocardial lesions at ventricular sites.
Źródło:
Metrology and Measurement Systems; 2012, 19, 3; 603-610
0860-8229
Pojawia się w:
Metrology and Measurement Systems
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Temperature Effect on Performance of Different Solar Cell Technologies
Autorzy:
Adeeb, Jehad
Farhan, Alaa
Al-Salaymeh, Ahmed
Powiązania:
https://bibliotekanauki.pl/articles/124356.pdf
Data publikacji:
2019
Wydawca:
Polskie Towarzystwo Inżynierii Ekologicznej
Tematy:
solar cell
photovoltaics
temperature effect
multicrystalline silicon solar cell
amorphous silicon solar cell
monocrystalline
Opis:
One of the main parameters that affect the solar cell performance is cell temperature; the solar cell output decreases with the increase of temperature. Therefore, it is important to select the proper solar cell technology that performs better at a specified location considering its average temperatures. In addition, the solar cell performance is directly reflected on the overall economics of the project. This paper is proposed to evaluate the variations in the performance of different solar cell technologies related to the temperature in Amman, Jordan. Field data of weather station and three PV systems (Poly-crystalline, Mono-crystalline and Thin-film) of identical design parameters were collected from Test Field Project at Applied Science Private University, Shafa Badran, Amman, Jordan. These data were analysed in the following way. estimated specific energy yield (kWh/kWp) for the three different PV systems was calculated depending on the measured value of solar irradiance and technical specifications of the installed solar panels and inverters, then the actual energy yield at different temperatures over one year was compared with the estimated value, so the deviations could be determined and actual temperature coefficients for energy yield could be calculated, knowing that the three PV Systems have identical design parameters (tilt angle, azimuth angle, type and dimensions of mounting structure and inverter size) and same cleaning method and schedule. It was found that the thin-film solar panels are less affected by temperature with temperature coefficient of -0.0984%, and -0.109%, -0.124% for Mono-crystalline and Poly-crystalline respectively. These results can be implemented in the preliminary design steps, specifically in the selection of the solar cell technology to be installed in a specific location.
Źródło:
Journal of Ecological Engineering; 2019, 20, 5; 249-254
2299-8993
Pojawia się w:
Journal of Ecological Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
On the modelling of thin uniperiodic cylindrical shells
Modelowanie cienkich powłok walcowych o jednokierunkowej periodyce
Autorzy:
Tomczyk, B.
Powiązania:
https://bibliotekanauki.pl/articles/281019.pdf
Data publikacji:
2003
Wydawca:
Polskie Towarzystwo Mechaniki Teoretycznej i Stosowanej
Tematy:
shell
modelling
dynamics
cell
Opis:
The aim of this contribution is to propose a new averaged model of dynamic problems for thin linear-elastic cylindrical shells having a periodic structure along one direction tangent to the shell midsurface. In contrast with the known homogenized models, the proposed one makes it possible to describe the effect of the periodicity cell size on the global dynamic shell behavior (a length-scale effect). In order to derive governing equations with constant or slowly varying coefficients, the known tolerance averaging procedure is applied. The comparison between the proposed model and the model without the length-scale effect as well as the known length-scale model for cylindrical shells with the periodic structure in both directions tangent to the shell midsurface is present.
Celem pracy jest wyprowadzenie uśrednionego modelu służącego do analizy dynamiki cienkich liniowo-sprężystych powłok walcowych mających periodyczną strukturę w jednym kierunku stycznym do powierzchni środkowej powłoki. Proponowany model, w przeciwieństwie do znanych modeli zhomogenizowanych, umożliwia badanie wpływu wielkości komórki periodyczności na dynamikę powłoki walcowej (wpływ ten zwany jest efektem skali). W celu wyprowadzenia równań o stałych lub wolnozmiennych współczynnikach zastosowano znaną metodę tolerancyjnego uśredniania. Wyprowadzony model porównano z modelem dla powłoki walcowej z periodyką w dwóch kierunkach wzajemnie prostopadłych i stycznych do powierzchni środkowej powłoki oraz z modelem bez efektu skali.
Źródło:
Journal of Theoretical and Applied Mechanics; 2003, 41, 4; 755-774
1429-2955
Pojawia się w:
Journal of Theoretical and Applied Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Phenomenon of ageing – a process or a state
Autorzy:
Klusek, Jolanta
Klusek, Justyna
Powiązania:
https://bibliotekanauki.pl/articles/472562.pdf
Data publikacji:
2016
Wydawca:
Uniwersytet Pedagogiczny im. Komisji Edukacji Narodowej w Krakowie
Tematy:
ageing
cell
brain
hormones
Źródło:
Annales Universitatis Paedagogicae Cracoviensis. Studia ad Didacticam Biologiae Pertinentia; 2016, VI; 42-51
2083-7267
2450-3487
Pojawia się w:
Annales Universitatis Paedagogicae Cracoviensis. Studia ad Didacticam Biologiae Pertinentia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pseudophysiological transcomplementary activation of reconstructed oocytes as a highly efficient method used for producing nuclear-transferred pig embryos originating from transgenic foetal fibroblast cells
Autorzy:
Samiec, M.
Skrzyszowska, M.
Lipinski, D.
Powiązania:
https://bibliotekanauki.pl/articles/32261.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
pseudophysiological activation
oocyte
reconstructed oocyte
nuclear-transferred embryo
pig
embryo
transgenic cell
fetal cell
fibroblast cell
preimplantation development
preimplantation development zob.tez embryonic development
cell cloning
Opis:
The completely new strategy of pseudophysiological transcomplementary (transcytoplasmic) activation (PP-TCA) of nuclear-transferred oocytes, which had been derived from pWAPhGH-GFPBsd transfected foetal fibroblast cells, was recently applied to the somatic cell cloning of pigs. It resulted in the considerable enhancing not only the cleavage activity of cultured cloned embryos, but also their morula and blastocyst formation rates as compared to the use of standard simultaneous fusion and electrical activation of reconstituted oocytes (77% vs. 57%, 63% vs. 46% and 40% vs. 27%, respectively). Altogether, the use of cytosolic components descended from heterologous (rabbit) zygotes as the agents for stimulation of porcine clonal cytoplasmic hybrids (cybrids) turned out to be reliable and feasible strategy for the generation of transgenic blastocysts by somatic cell nuclear transfer (SCNT). Furthermore, to our knowledge, no previous study has reported the preimplantation developmental outcome of transgenic nuclear-transferred pig embryos following the PP-TCA that was developed and optimised in our laboratory.
Źródło:
Polish Journal of Veterinary Sciences; 2012, 15, 3
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 16-30 z 1166

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