Skocz do pozycji: 1.

Tytuł:

Das Schwache Verb und seine Exponenten vom Mittel- bis zum Neuhochdeutschen

Autorzy:

Woźnicka, Marta

Powiązania:

https://bibliotekanauki.pl/articles/2076083.pdf

Data publikacji:

2015

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

verb
verb components
inflection markers
tense markers
mode markers

Opis:

In the article a new method of determining the so-called markers of inflexion, tense and mode of synthetic forms within the group of weak verbs was presented, and the whole concept is based on the innovative model of a linguistic analysis developed by Jozef Darski (1987; 22004). The model mentioned above is adapted for diachronic analysis, which allows to depict the development of the markers enumerated above from mid- to new-high-German.

Źródło:

Kwartalnik Neofilologiczny; 2015, 4; 703-713
0023-5911

Pojawia się w:

Kwartalnik Neofilologiczny

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 2.

Tytuł:

Specialized Movement on the Rowing Ergometer and Post-workout Changes in Selected Peripheral Blood Parameters - a Case Report.

Autorzy:

Proia, Patrizia
Amato, Alessandra
Contró, Valentina
Thiel, Dan
Vostatková, Pavlína
Buryta, Beata
Kolbowicz, Marek
Lewandowski, Tomasz
Nowakowska, Anna

Powiązania:

https://bibliotekanauki.pl/articles/1030593.pdf

Data publikacji:

2018

Wydawca:

Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego

Tematy:

biochemical markers
haematological markers
matrix metalloproteinases
rowing

Opis:

Rowing is a sport discipline, which requires extreme physical strength and endurance and appropriate aerobic and anaerobic capacity as well. However, when the workout intensity and load is very high, exercise is associated with temporary changes in cellular metabolism and the immune system. The study included one male rower aged 28 years - the highly-skilled and experienced athlete. We determined basic cardiorespiratory fitness measures, complete blood count, and 24 clinical chemistry parameters including relevant biochemical and haematological parameters and matrix metaloproteinases activities. Maximal exercise on the rowing ergometer induced 2-fold increase in absolute counts of all leukocytes subsets. There was observed an increase in C-reactive protein concentrations as well. MMP-9 activity increased 1,3-fold compared to the baseline value. Exhaustive exercise caused significant changes in creatinine and urea serum levels, but the most prominent changes were found in total and direct bilirubin concentrations. Maximal exercise induced also a decrease in the iron and magnesium levels. No changes in ALT, GGT and ALP activity were observed, while increase in CK, AST and LDH activity in post-exercise time and the decrease during the recovery was found. Therefore acute specialized movement on the rowing ergometer is not the cause of muscular damage, but rather indicate efficient adaptation to the physical exercise. Moreover, it seems that maximal exercise induces an inflammatory response characterized by greater count of all subpopulations of leukocytes, elevated levels of CRP and MMP-9 serum activity.

Źródło:

Central European Journal of Sport Sciences and Medicine; 2018, 24, 4; 5-13
2300-9705
2353-2807

Pojawia się w:

Central European Journal of Sport Sciences and Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 3.

Tytuł:

The effect of wrestling tournament on immune and endocrine markers in blood and saliva of male and female athletes

Autorzy:

Trochimiak, Teresa
Hübner-Woźniak1, Elżbieta

Powiązania:

https://bibliotekanauki.pl/articles/1054825.pdf

Data publikacji:

2014

Wydawca:

Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego

Tematy:

blood
endocrine markers
immune markers
saliva
tournament
wrestlers

Opis:

The aim of the present study was to determine the effect of one-day wrestling tournament on magnitude and direction of changes in selected immunological and endocrine status indices. The participants of the study were male (n = 12) and female (n = 13) wrestlers. The earlobe blood samples and unstimulated saliva were collected at three time points: in the morning before the competition (1), immediately after the last match (2) and in the next morning (3). Total protein, IgA and cortisol concentration and α-amylase activity in saliva, as well as concentration of cortisol and interleukin-6 in serum were measured. Significantly lower ratio of sIgA/protein and significantly higher levels of salivary and serum cortisol, interleukin-6, and α-amylase activity were observed at the second time point compared with the first and the third in both groups of athletes. Regardless of the examined time point, concentrations of serum and saliva markers were similar in female and male wrestlers. However, a tendency to lower sAA activity on the next morning after the tournament compared to basal activity of this enzyme was seen in both examined groups. In general, the changes of examined markers were short-lived, except for α-amylase activity, showing that tournament-wrestling matches had no sustained negative effects on endocrine and immunological body systems.

Źródło:

Central European Journal of Sport Sciences and Medicine; 2014, 7, 3; 81-89
2300-9705
2353-2807

Pojawia się w:

Central European Journal of Sport Sciences and Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 4.

Tytuł:

Immunohistochemical assessment of metalloproteinases MMP2 and MMP9 expression in canine various subtypes of lymphomas in relation with proliferative and apoptotic markers

Autorzy:

Sokołowska, J.
Urbańska, K.

Powiązania:

https://bibliotekanauki.pl/articles/2087535.pdf

Data publikacji:

2019

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

apoptotic markers
dog
immunolabelling
lymphoma
matrix metalloproteinases
proliferative markers

Źródło:

Polish Journal of Veterinary Sciences; 2019, 2; 203-211
1505-1773

Pojawia się w:

Polish Journal of Veterinary Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 5.

Tytuł:

Association between clinical stage of oral cancer and expression of immunohistochemical markers

Autorzy:

Świątkowski, Wojciech
Rahnama, Mansur
Tomaszewski, Tomasz
Bigas, Mariola
Świątkowska, Agnieszka
Łobacz, Michał
Wallner, Jan

Powiązania:

https://bibliotekanauki.pl/articles/1393147.pdf

Data publikacji:

2017

Wydawca:

Index Copernicus International

Tematy:

oral cancer
neoplasm markers
squamous cell carcinoma
proliferation markers

Opis:

Aim: The aim of this study is to demonstrate the possible correlation between the expression of examined protein markers - p53, EGFR, PCNA, p44/42 in the mass of the tumor and the clinical stage of disease. Material: 48 patients of the Department and Clinic of Oral and Maxillofacial Surgery, Lublin diagnosed with oral cancer. The control group consisted of 10 patients diagnosed with leukoplakia lesions in the oral cavity. The methods: Immunohistochemical analysis using the detection system DAKO K5007 Cat - Dako REAL ™ Detection System, Peroxidase DAB +, Rabbit / Mouse. Results: Based upon the statistical results, significant correlation between p53 protein and tumor staging; however, a correlation between the level of expression of EGFR, p44/42, PCNA and staging was not likewise revealed. Conclusions: Looking for oral squamous cell carcinoma markers remains an actual issue. Identification of specific markers of oral cancer could be used in screening the population, determining prognosis and response to treatment.

Źródło:

Polish Journal of Surgery; 2017, 89, 6; 17-22
0032-373X
2299-2847

Pojawia się w:

Polish Journal of Surgery

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 6.

Tytuł:

Biochemiczna diagnostyka nowotworów narządu płciowego kobiety – co nowego?
Biochemical diagnostics of gynecological malignancies – what’s new?

Autorzy:

Kamińska, Janina
Kowalska, Maria
Kotowicz, Beata
Fuksiewicz, Małgorzata
Siedlecka, Alicja
Bidziński, Mariusz

Powiązania:

https://bibliotekanauki.pl/articles/908180.pdf

Data publikacji:

2006

Wydawca:

Medical Communications

Tematy:

cervical carcinoma
cytokines
diagnostic sensitivity
markers of bone turnover
tumor markers

Opis:

The analysis of the utility of serum SCC determination, combined with other tumor markers and cytokine assessment in cervical cancer patients, was performed. However, only CA 125 levels were found to relate to the histopathological type of the tumor, and were higher in adenocarcinoma. In addition, in patients with adenocarcinoma, CA 125 presented higher diagnostic sensitivity than CEA, standard tumor marker for cervical cancer. We have also shown that complementary IL-6 and SCC assessment in patients with cervical cancer improve the diagnostic sensitivity, independent of histopathological type. This would be especially important for early diagnostics and monitoring of patients. We have also demonstrated the possible use of bone metabolism markers in patients after oncological treatment with posttreatment osteoporosis, which is a common side effect of cancer treatment. Actually, bone metabolism markers join the array of tumor markers, to monitor osteoporosis treatment. For the monitoring purposes, these markers are more efficient than densitometry methods. Our preliminary results on osteocalcin, PINP and Ctx point at PINP as the most promising marker.
W pracy analizowano przydatność oznaczania SCC z innymi markerami nowotworowymi i cytokinami w surowicy krwi chorych na raka szyjki macicy. Analizując zależność pomiędzy stężeniami badanych markerów nowotworowych i cytokin a typem histopatologicznym, stwierdzono, że stężenia CA 125 były istotnie wyższe u chorych na gruczołowego raka szyjki macicy. Ponadto wykazano, że u chorych na gruczołowego raka szyjki macicy oznaczanie stężeń CA 125 ma większą przydatność diagnostyczną niż oznaczenia CEA, który uznawany jest za standardowy marker dla tego nowotworu. Stwierdzono również, że oznaczanie IL-6 z SCC u chorych na raka szyjki macicy, niezależnie od typu histopatologicznego, zwiększa czułość diagnostyczną, co ma szczególne znaczenie we wczesnych stopniach zaawansowania klinicznego i może być przydatne do monitorowania wyników leczenia. Omówiono także możliwość wykorzystania markerów obrotu kostnego po leczeniu onkologicznym, które jest często przyczyną licznych powikłań, między innymi takich jak osteoporoza. W chwili obecnej panel markerów nowotworowych został poszerzony o markery obrotu kostnego, które mogą być przydatne w ocenie skuteczności leczenia osteoporozy. Od niedawna stosowane markery obrotu kostnego umożliwiają ocenę skuteczności leczenia w znacznie krótszym czasie niż metody densytometryczne. Do najczęściej wykorzystywanych markerów należą: osteokalcyna, PINP i Ctx. Wyniki naszych wstępnych badań sugerują jednak, że największą przydatność ma oznaczanie stężeń PINP.

Źródło:

Ginekologia Onkologiczna; 2006, 4, 1; 10-13
1731-5379

Pojawia się w:

Ginekologia Onkologiczna

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 7.

Tytuł:

Pro-inflammatory properties of cadmium

Autorzy:

Olszowski, Tomasz
Baranowska-Bosiacka, Irena
Gutowska, Izabela
Chlubek, Dariusz

Powiązania:

https://bibliotekanauki.pl/articles/1039631.pdf

Data publikacji:

2012

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

inflammatory mediators and markers
cadmium

Opis:

Cadmium is a toxic and carcinogenic heavy metal that nowadays constitutes a serious environmental health problem. The aim of this study is to review the effects of cadmium on selected inflammatory mediators and markers, such as NF-κB and AP-1 transcription factors, IL-6, TNF-α, IL-1β cytokines, IL-8 or MIP-2 chemokine, MPO, iNOS, MMPs and COX-2 enzymes, PGE2 (product of COX-2 enzyme), ICAM-1, VCAM-1 and PECAM-1 adhesion molecules, and CRP. The research strategy identified articles available in Medline, published between 1998 and 2012; we included both in vivo and in vitro studies carried out on humans and rodents. Most of the reviewed research findings suggest that cadmium in micromolar concentrations (especially in the 1-10 μM range) causes up-regulation of the mediators and markers of inflammation, and appears to have pro-inflammatory properties. However, it is worth mentioning that a contradictory or even opposite hypothesis exists, which suggests cadmium to be an anti-inflammatory factor. Further research including detailed histological analyses should solve this discrepancy. Nevertheless, it appears that the main reason for these contradictory findings is the experimental setup: different biological systems analyzed and different doses of cadmium applied.

Źródło:

Acta Biochimica Polonica; 2012, 59, 4; 475-482
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 8.

Tytuł:

Circulating cytokeratin-18 and tumour necrosis factor-α in patients with alcoholic liver cirrhosis

Autorzy:

Prystupa, Andrzej
Kiciński, Paweł
Niedziałek, Jarosław
Toruń-Jurkowska, Anna
Boguszewska-Czubara, Anna
Luchowska-Kocot, Dorota
Ochal, Andrzej
Jojczuk, Mariusz
Sak, Jarosław

Powiązania:

https://bibliotekanauki.pl/articles/972347.pdf

Data publikacji:

2016

Wydawca:

Instytut Medycyny Wsi

Tematy:

liver cirrhosis
alcohol
apoptosis markers

Opis:

Aims. The aim of the study was to assess the usefulness of TNF-α and CK-18 as diagnostic markers of alcoholic liver cirrhosis. Additionally, the effects of the stage of liver cirrhosis on concentrations of TNF-α and CK-18, as well as their correlation, were evaluated. Materials and method. Sixty-two patients with alcoholic liver cirrhosis treated in various hospitals were randomly enrolled. The stage of cirrhosis was assessed according to the Child-Turcotte-Pugh scoring system. The control group consisted of 31 healthy people without liver disease. Concentrations of TNF-α and cytokeratin-18 in blood plasma of patients and controls were measured using the sandwich enzyme immunoassay technique, with commercially available quantitative ELISA test kits. Results. The concentration of CK-18 was statistically higher in patients with alcoholic liver cirrhosis, compared to the control group. The concentration of TNF-α was significantly higher in patients with alcoholic liver cirrhosis, compared to the control group. Higher concentrations of TNF-α were found only in patients with stage C and B alcoholic liver cirrhosis, compared to healthy persons. Conclusions. The levels of TNF-α and total CK-18 were higher in patients with alcoholic liver cirrhosis than in healthy individuals. No correlation was found between the level of CK-18 and stage of liver cirrhosis.

Źródło:

Journal of Pre-Clinical and Clinical Research; 2016, 10, 2; 87-90
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 9.

Tytuł:

Grammatikalisierung, Pragmatikalisierung und die Entstehung von Diskursmarkern im Deutschen

Autorzy:

Rojek, Tomasz

Powiązania:

https://bibliotekanauki.pl/articles/700373.pdf

Data publikacji:

2013

Wydawca:

Stowarzyszenie Germanistów Polskich

Tematy:

grammaticalisation, pragmatisation, discourse markers, particle

Opis:

Since about 20 years linguists attempt to apply the grammaticalisation concept to the description of pragmatic phenomena. In this context some linguists speak about ‘pragmatisation’ – a kind of language change, which concerns the linguistic codification of certain pragmatic contents. The term ‘pragmatisation’ suggests a new process, which runs in opposite direction to the development of grammatical elements. Irrespective of how we define the relation between both processes, this means always a reinterpretation (mostly extention) of the grammaticalisation concept. The present article focus on the question whether such attempts indeed result in a new insight into development of pragmatic units, or lead to terminological confusion by different terming already well described linguistic mechanisms.

Źródło:

Zeitschrift des Verbandes Polnischer Germanisten; 2013, 2, 2
2353-656X
2353-4893

Pojawia się w:

Zeitschrift des Verbandes Polnischer Germanisten

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 10.

Tytuł:

Sclerostin and bone metabolism markers in hyperthyroidism before treatment and interrelations between them

Autorzy:

Sarıtekin, İlker
Açıkgöz, Şerefden
Bayraktaroğlu, Taner
Kuzu, Fatih
Can, Murat
Güven, Berrak
Mungan, Görkem
Büyükuysal, Çağatay
Sarıkaya, Selda

Powiązania:

https://bibliotekanauki.pl/articles/1038540.pdf

Data publikacji:

2017

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

hyperthyroidism
sclerostin
bone metabolism markers

Opis:

Sclerostin, which is a glycoprotein produced by osteocytes, reduces the formation of bones by inhibiting the Wnt signal pathway. Thyroid hormones are related with Wnt signal pathway and it has been reported that increased thyroid hormones in hyperthyroidism fasten epiphysis maturation in childhood, and increase the risk of bone fractures by stimulating the bone loss in adults. The aim of this study was to examine the sclerostin serum levels, the relation between sclerostin and thyroid hormones as well as the biochemical markers of the bone metabolism in patients with hyperthyroidism (including multinodular goiter and Graves' disease), whose treatments have not started yet. No difference was found in the serum sclerostin levels between the hyperthyroidism group (n=24) and the control group (n=24) (p=0.452). The serum osteocalcin levels and 24-hour urinary phosphorus excretion were found to be higher in the hyperthyroid group than in the control group (p<0.001, p=0.009). A positive correlation was determined between the sclerostin and bone alkaline phosphatase levels (p<0.001); a negative correlation between the osteocalcin and thyroid stimulating hormone (TSH) (p<0.05); a positive correlation between the osteocalcin and thyroid hormones (FT3,FT4) (p<0.001); and a positive correlation between the deoxypyridinoline and hydroxyproline (p<0.001). No correlation was determined between sclerostin and TSH,FT3,FT4 (p>0.05). Therefore, we consider that a long-term study that covers the pre-post treatment stages of hyperthyroidism, including both the destruction and construction of the skeleton would be more enlightening. Moreover, the assessment of the synthesis of sclerostin in the bone tissue and in the serum level might show differences.

Źródło:

Acta Biochimica Polonica; 2017, 64, 4; 597-602
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 11.

Tytuł:

Pragmatic marker tu as a source of implicature in Kiswahili

Autorzy:

Kibiki, Magreth J.
Pawlik, Jacek Jan
Różański, Jarosław

Powiązania:

https://bibliotekanauki.pl/chapters/31233271.pdf

Data publikacji:

2023-10-27

Wydawca:

Uniwersytet Warszawski. Wydawnictwa Uniwersytetu Warszawskiego

Tematy:

pragmatic markers
spoken Kiswahili
implicature theory

Opis:

This study examines the pragmatic marker tu as a source of implicature in Kiswahili. The natural observation method was used to collect data from Kiswahili speakers in their normal daily conversations, which was then analyzed using Grice’s (1975) implicature theory. It was observed that the pragmatic marker tu conveys various implicatures depending on the context of use. These include expressing inadequacy or insufficiency, signaling dissatisfaction, showing contempt, inevitability and simplicity. Interestingly, the findings of the study also showed that intonation plays a role in determining the implicature invoked by this marker.

Źródło:

Language, Culture, Literature Intertwined. The Swahili Perspective; 117-136
9788323561996

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 12.

Tytuł:

Biotechnology of temperate fruit trees and grapevines

Autorzy:

Laimer, Margit
Mendonça, Duarte
Maghuly, Fatemeh
Marzban, Gorji
Leopold, Stephan
Khan, Mahmood
Balla, Ildiko
Katinger, Hermann

Powiązania:

https://bibliotekanauki.pl/articles/1041374.pdf

Data publikacji:

2005

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

plant biotechnology
patogen detection
molecular markers

Opis:

Challenges concerning fruit trees and grapevines as long lived woody perennial crops require adapted biotechnological approaches, if solutions are to be found within a reasonable time frame. These challenges are represented by the need for correct identification of genetic resources, with the foreseen use either in conservation or in breeding programmes. Molecular markers provide most accurate information and will be the major solution for questions about plant breeders rights. Providing healthy planting material and rapid detection of newly introduced pathogens by reliable methods involving serological and molecular biological tools will be a future challenge of increases importance, given the fact that plant material travels freely in the entire European Union. But also new breeding goals and transgenic solutions are part of the biotechnological benefits, e.g. resistance against biotic and abiotic stress factors, modified growth habits, modified nutritional properties and altered processing and storage qualities. The successful characterization of transgenic grapevines and stone fruit trees carrying genes of viral origin in different vectors constructed under ecological consideration, will be presented. Beyond technical feasibility, efficiency of resistance, environmental safety and Intellectual Property Rights, also public acceptance needs consideration and has been addressed in a specific project. The molecular determination of internal quality parameters of food can also be addressed by the use of biotechnological tools. Patient independent detection tools for apple allergens have been developed and should allow to compare fruits from different production systems, sites, and genotypes for their content of health threatening compounds.

Źródło:

Acta Biochimica Polonica; 2005, 52, 3; 673-678
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 13.

Tytuł:

Use of AFLP Molecular Markers for Estimating Genetic Similarity of Alfalfa (Medicago Sativa L. Sl.)

Autorzy:

Dobrzycka, Agnieszka
Broda, Zbigniew
Bocianowski, Jan
Ćwiklinska, Anna

Powiązania:

https://bibliotekanauki.pl/articles/2199044.pdf

Data publikacji:

2009-12-20

Wydawca:

Instytut Hodowli i Aklimatyzacji Roślin

Tematy:

AFLP markers
alfalfa
genetic similarity
diversity

Opis:

The aim of study was to determine genetic similarity among sixteen alfalfa populations using the AFLP technique. Plant material was selected considering the high genotypic variability. It included populations of different origin: native forms of alfalfa (secondary ecotypes), inbred lines, single hybrids, synthetic populations, varieties and mutants...

Źródło:

Plant Breeding and Seed Science; 2009, 60; 61-71
1429-3862
2083-599X

Pojawia się w:

Plant Breeding and Seed Science

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 14.

Tytuł:

Assessment of Potato Resistance to Synchytrium Endobioticum

Autorzy:

Przetakiewicz, Jarosław
Plich, Jarosław

Powiązania:

https://bibliotekanauki.pl/articles/2199702.pdf

Data publikacji:

2017-12-20

Wydawca:

Instytut Hodowli i Aklimatyzacji Roślin

Tematy:

potato wart disease
resistance
molecular markers

Opis:

In Poland the Plant Breeding and Acclimatization Institute - National Research Institute (IHAR-PIB) is responsible for officially assessing the resistance of potato breeding lines and cultivars to Synchytrium endobi-oticum. In the official assessment of wart resistance the modified Glynne-Lemmerzahl method is used. A full cycle of assessment of the wart disease resistance requires 42 - 45 tubers per cultivar/breeding line. Forty two tubers are used in laboratory tests. To complete the laboratory tests, another 10 tubers are inoculated with winter sporangia of the fungus, using ring test. The final results are available after 3 years of investigation. If necessary, the full cycle of resistance tests to S. endobioticum can be performed during one year on 15 tubers in each of the 3 replications (45 tubers in total).Molecular verification of potato genotypes resistance to pathotype 1(D1) is possible with the use of SCAR marker Nl25-1400. Nevertheless, an official phenotypical assessment of advanced breeding lines, as the final verification of their resistance, is required.

Źródło:

Plant Breeding and Seed Science; 2017, 76; 37-43
1429-3862
2083-599X

Pojawia się w:

Plant Breeding and Seed Science

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 15.

Tytuł:

The Conceptual Distiction between Polish Markers of Reflexivity siebie and się

Autorzy:

Drogosz, Anna

Powiązania:

https://bibliotekanauki.pl/articles/445038.pdf

Data publikacji:

2005

Wydawca:

Uniwersytet Warmińsko-Mazurski w Olsztynie

Tematy:

Polish Markers (się, siebie)
Conceptual Distiction

Opis:

The article discusses reflexivity as a departure from the canonical event model and examines the distinction between two Polish markers of reflexivity: siebie and się. Both these markers code the direct reflexive situation type but semantically and syntactically they are not always interchangeable. This distinction is explained within Langacker's Cognitive Grammar framework and attributed to the difference in profile, trajector/landmark alignment and construal that these markers impose on a given situation. The article suggests that siebie functions as a nominal reflexive marker, which profiles a thing, and in a reflexive construction stands as the landmark of a relation. Thus siebie imposes the construal of volitionality and contrastiveness, and syntactically, it is obligatory as a prepositional complement and after verbs of perception. Się is a relational reflexive, and as such it profiles a relation, and specifies the identity of trajector and landmark of a relation, which become conflated in the single participant, i.e. the referent of the sentence subject. Consequently, the się-constructions are neutral with respect to intentionality of the profiled action, and conceptually simpler than siebie-constructions, which accounts for their higher frequency of occurrence.

Źródło:

Acta Neophilologica; 2005, VII; 107-118
1509-1619

Pojawia się w:

Acta Neophilologica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 16.

Tytuł:

Detection of circulating breast cancer cells in peripheral blood by a two-marker reverse transcriptase-polymerase chain reaction assay.

Autorzy:

Fabisiewicz, Anna
Kulik, Jadwiga
Kober, Paulina
Brewczyńska, Elżbieta
Pieńkowski, Tadeusz
Siedlecki, Janusz

Powiązania:

https://bibliotekanauki.pl/articles/1041553.pdf

Data publikacji:

2004

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

RT-PCR
breast cancer
molecular markers

Opis:

The aim of this study was to use a two-marker assay for the detection of breast cancer cells circulating in patients' blood. We have applied a PCR-based methodology to follow up the possibility of the development of metastatic disease in stage I and II patients who had undergone curative surgery. Since the number of circulating cancer cells in peripheral blood is very low, the technique for their detection needs to be not only highly sensitive, but also very specific. The reverse transcriptase-polymerase chain reaction (RT-PCR) technique may improve the sensitivity of breast cancer cell detection up to only a few cells per one million. The principle of the RT-PCR assay is to amplify a messenger RNA characteristic for breast epithelial cells in a blood sample. Since we do not expect such cells to be circulating in peripheral blood of healthy subjects, detection of the characteristic mRNA should indicate the presence of circulating breast cancer cells. We analyzed the usefulness of three mRNA markers: cytokeratin 19 (CK19), mammaglobin (hMAM) and β subunit of human chorionic gonadotropin (β-hCG) for this test. Blood samples (112) were obtained from 55 patients, in stages I and II, with or without metastasis to regional lymph nodes (N0 or N1). We found that a two-marker assay increases the sensitivity of detection of breast cancer cells in comparison with a single-marker one. Combination of two tumor-specific mRNA markers, hMAM/CK19 or β-hCG/CK19, allowed the detection of circulating breast cancer cells in 65% of N1 patients and 38% of N0 patients. By comparison, the combination hMAM/β-hCG allowed the detection of circulating breast cancer cells in the blood of 68% of N1 patients and 46% of N0 patients. Addition of the third marker did not significantly increase the detection sensitivity.

Źródło:

Acta Biochimica Polonica; 2004, 51, 3; 747-755
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 17.

Tytuł:

The impact of physical effort on cortisol level: a review of the latest report

Autorzy:

Grzebisz, Natalia

Powiązania:

https://bibliotekanauki.pl/articles/1189840.pdf

Data publikacji:

2016

Wydawca:

Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN

Tematy:

effort
cortisol
saliva
overtraining
biochemical markers

Opis:

The results of the current study demonstrate that exercise interferes with the hormonal balance system. The size and direction of these changes depend on the volume and intensity of a physical effort. Biochemical monitoring can support the process of training and gathered data can assist in countering the effects of overtraining. The article presents the latest reports on the character of the changes in cortisol influenced by various types of physical effort, the impact of the training units, time of their execution and the influence of the supply of carbohydrates on the level of this hormone in the body. This work also presents the advantages of saliva analysis, as a reliable material to measure the level of cortisol in athletes.

Źródło:

World Scientific News; 2016, 48; 205-210
2392-2192

Pojawia się w:

World Scientific News

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 18.

Tytuł:

Comparison of RAPD, ISSR and SSR markers in assessing genetic diversity among rye*(Secale cereale L.) inbred lines

Autorzy:

Myśków, Beata
Milczarski, Paweł
Masojc, Piotr

Powiązania:

https://bibliotekanauki.pl/articles/2199589.pdf

Data publikacji:

2010-12-01

Wydawca:

Instytut Hodowli i Aklimatyzacji Roślin

Tematy:

dendrogram
genetic diversity
molecular markers
rye

Opis:

Forty eight inbred lines of winter rye, of various origin and pedigree, were analysed using 19 RAPD (random amplified polymorphic DNA) primers, 8 ISSR (inter-simple sequence repeats) primers and 13 SSR (simple sequence repeats) primer pairs. On the basis of particular marker types, there were created three separate dendrograms and one combined similarity tree, prepared on account of the whole data. Correlation coefficients for individual technique based on genetic similarity matrices were not significant. By comparing the GS data obtained on the basis of singular methods with collective matrix, it was observed that the highest correlation rate was for ISSR method (r=0.68). The utility of each marker technique was compared by using marker index MI. Diversity detecting index (DDI) was suggested in the paper, which may prove helpful in planning and comparing researches on phenetic relationships...

Źródło:

Plant Breeding and Seed Science; 2010, 62; 107-116
1429-3862
2083-599X

Pojawia się w:

Plant Breeding and Seed Science

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 19.

Tytuł:

The Pragmatic Functions of the Marker Sawa in Spoken Swahili

Autorzy:

Kibiki, Magreth J.

Powiązania:

https://bibliotekanauki.pl/articles/462497.pdf

Data publikacji:

2019-12-13

Wydawca:

Uniwersytet Warszawski. Wydział Orientalistyczny. Katedra Języków i Kultur Afryki

Tematy:

pragmatic markers, spoken Swahili, contextualization theory

Opis:

This study examines the pragmatic functions of the marker sawa in spoken Swahili. The data have been obtained from informal conversations made by Swahili speakers in informal social settings. These settings include “vijiwe vya kahawa” (setting of informal conversations created around people drinking coffee) and "vijiwe vya mamantilie” (setting of informal conversations created around women preparing and selling food on the streets). The analysis of the data, performed within the framework of the contextualization theory (Gumperz 1982), shows that, apart from its basic connotation of agreement, the marker sawa conveys other meanings, depending on these very contexts of communication, and therefore acquires also various pragmatic functions. The pragmatic functions identified in this work include: to show that the speaker agrees with what has been said but on a condition (I agree, but…), as a receipt marker, as a tag-positioned-comprehension check, as an answer to the question showing that the speaker has understood what has been said (Yes, I understand), as a continuer, as a negative releasing marker, and as a gap filler. Interestingly, the study shows also that intonation and other paralinguistic features (like gestures) play a role in determining the pragmatic functions of this marker. The article concludes that the pragmatic markers in spoken Swahili are rich in meanings and are used to show speakers’ attitudes and emotions, therefore manifesting a deep and meaningful interconnection between the language and its contextualized experience.

Źródło:

Studies in African Languages and Cultures; 2019, 53; 29-56
2545-2134
2657-4187

Pojawia się w:

Studies in African Languages and Cultures

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 20.

Tytuł:

Current and potential oncomarkers in diagnosing breast cancer
Obecnie używane i potencjalne markery nowotworowe w diagnostyce raka piersi

Autorzy:

Bilecová-Rabajdová, M.
Urban, P.
Grešová, A.
Varga, J.
Gregová, K.
Stupák, M.
Mareková, M.

Powiązania:

https://bibliotekanauki.pl/articles/271594.pdf

Data publikacji:

2012

Wydawca:

Górnośląska Wyższa Szkoła Pedagogiczna im. Kardynała Augusta Hlonda

Tematy:

rak piersi
diagnostyka
markery molekularne
markery nowotworowe TVMs
breast cancer
diagnostics
molecular markers
tumour vascular markers

Opis:

Breast cancer is a very serious disease from both an economical and social point of view, because of its high incidence and mortality, as well as its prevalence. Genetic and epigenetic changes as well as the resultant deregulation of mechanisms that affect cellular processes are reflected in the final stage, like significant variability in phenotype. These changes have multiple factors in clinical, morphological but also molecular terms, and they greatly affect the possibility of accurate diagnosis of breast cancer in its early stages. Since no combination of clinical examination, mammography and ultrasonography together with CT and MRI can achieve 100% sensitivity, clinical practice is supported with diagnostic methods based on the monitoring of tumour markers with the emphasis on molecular markers. This review describes the most common molecular markers already used for earlier clinical diagnostics and also proposes new possible markers from the tumour vascular markers group. Any new oncomarkers to improve diagnostic sensitivity and specificity will be of great benefit, and in clinical practice, they may provide an opportunity for early diagnostic and therapeutic intervention, and subsequently better prognosis for the patient as well.
Rak piersi jest bardzo poważną chorobą, zarówno z punktu widzenia ekonomicznego jak i społecznego, ze względu na dużą zachorowalność i umieralność, a także na zakres jego występowania. Zmiany genetyczne i epigenetyczne, jak również wynikająca z nich deregulacja mechanizmów, które wpływają na procesy komórkowe są odzwierciedlone w ostatnim stadium choroby, jak znaczna zmienność fenotypu. Zmiany te mają wiele przyczyn z punktu widzenia klinicznego, morfologicznego, ale również molekularnego oraz znacznie wpływają na możliwość dokładnego rozpoznania raka piersi w jego wczesnych fazach. Ponieważ żadna kombinacja badań klinicznych, mammografii i USG wraz z tomografią komputerową i obrazowaniem magnetyczno-rezonansowym nie może osiągnąć 100% czułości, praktyka kliniczna jest wspierana metodami diagnostycznymi opartymi na monitoringu markerów nowotworowych, ze szczególnym uwzględnieniem markerów molekularnych. Niniejsza recenzja opisuje najbardziej typowe markery molekularne wykorzystywane we wczesnej diagnostyce klinicznej, a także proponuje nowe potencjalne markery z grupy markerów nowotworowych TVMs . Wszelkie nowe markery nowotworowe poprawiające czułość i dokładność diagnostyki będą bardzo pomocne, a w praktyce klinicznej mogą pozwolić na wczesną diagnostykę i leczenie, co polepszy także rokowania pacjenta.

Źródło:

Journal of Ecology and Health; 2012, R. 16, nr 3, 3; 138-143
2082-2634

Pojawia się w:

Journal of Ecology and Health

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 21.

Tytuł:

Autosomal DNA Polymorphisms of Four South India Tribal Populations

Autorzy:

Deva, A.
Nandakumar, R.
Raghu, P.
Prabhakaran, K.

Powiązania:

https://bibliotekanauki.pl/articles/1190117.pdf

Data publikacji:

2016

Wydawca:

Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN

Tematy:

Tribal
Dravidian
Genome Diversity
Heterozygosity
Autosomal Markers

Opis:

Background: The entry and dispersal of modern humans is India of remains unclear and extending with many interesting evidences South India, assumed to be a major corridor for their with many ancient genetic deposits such as Dravidian tribal with Negrito features. As the relationships between the genetic polymorphs and diseases in human being revealed globally, it is worthy to investigate the genomic architecture of population in south India. Objective: To examine what evolutionary forces have most significantly impacted south Indian tribal genetic variation, and to test whether the phenotypic similarities of some south Indian tribal groups to Africans represent a signature of close relationship to Africans or are due to convergence. Methods: Blood samples from 193 unrelated individuals of both sexes are drawn from the Dravidian tribal settlements of Tamil Nadu and Kerala. South India are genotyped for four Aluindel (Alu FXIIIB, Alu ACE, AluTA25 and Alu PLAT) allele profile by PCR genotyping method. Results: All loci are highly polymorphic and average heterozygositiesare substantial (range: 0.37-0.44). Genetic differentiation is high (Gst = 3.7%) in all the study populations.

Źródło:

World Scientific News; 2016, 35; 62-72
2392-2192

Pojawia się w:

World Scientific News

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 22.

Tytuł:

Assessment of bone sialoprotein in the saliva of women at peri- and postmenopausal age

Autorzy:

Piątek, Dominika
Bachanek, Teresa
Donica, Helena
Chałas, Renata

Powiązania:

https://bibliotekanauki.pl/articles/972428.pdf

Data publikacji:

2016

Wydawca:

Instytut Medycyny Wsi

Tematy:

bone sialoprotein
saliva
osteoporosis
bone turnover markers

Opis:

Introduction and objective. Bone sialoprotein (BSP) is present in a non-collagenous fraction of bone matrix, in dentine, cement and calcified cartilage. The characteristic place where sialoprotein is produced makes it highly specific in relation to the bone tissue and the possibility of using it as a marker of bone metabolism. The study aimed to assess the BSP level in the saliva of female patients at the menopausal and postmenopausal period. Materials and method. The study included 71 women aged 45–74 years. In the examined subjects, bone mineral density and bone sialoprotein levels in saliva were determined. Patients also responded to survey questions about place of residence and the frequency of consumption of foods rich in calcium. The obtained results were statistically analyzed. Results. In the study population of women, BSP saliva concentration ranged from 0.40–14.97 ng/ml. The highest BSP values were observed in the control group (average – 5.66 ng/ml, median – 6.73 ng/ml,), the lowest in the osteopenia group (average – 3.09 ng/ml, median – 1.71 ng/ml). This relationship was close to statistical significance (p = 0.056). Place of residence of the surveyed women had neither effect on BSP concentration in saliva nor on the value of the T-score ratio. Similarly, there was no statistically significant relationship between the frequency of consumption of foods rich in calcium and BSP and T-score. Conclusions. It was found that the BSP level can be determined in saliva. Biochemical tests of saliva considering bone metabolism are an issue that should be continued in future, as the availability of material (saliva) for laboratory analyses, carries potential diagnostic opportunities.

Źródło:

Journal of Pre-Clinical and Clinical Research; 2016, 10, 2; 100-104
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 23.

Tytuł:

Habilitación y obsolescencia de marcadores discursivos
Developement and obsolescence of discursive markers

Autorzy:

Ridruejo, Emilio

Powiązania:

https://bibliotekanauki.pl/articles/1048240.pdf

Data publikacji:

2019-12-15

Wydawca:

Uniwersytet im. Adama Mickiewicza w Poznaniu

Tematy:

discourse markers
grammaticalization
functional change
pragmatic change

Opis:

The starting hypothesis of the article is that the discursive operators of Spanish have not been enabled by grammaticalization processes identical to those of other grammatical components (such as verbal or nominal morphemes or prepositions and conjunctions), since there has been no reduction in the functional scope nor a total bleaching, so that its link with the original lexical items has not disappeared. The consequence is that markers are not integrated into paradigms as closed as grammatical paradigms and both their obsolescence and their renewal, therefore, follow similar patterns to what happens in the evolution of the lexicon. This hypothesis is tried to verify in the article by means of the examination of some discursive markers that, having been used diachronically in Spanish, have been abandoned ina relatively short time.

Źródło:

Studia Romanica Posnaniensia; 2019, 46, 4; 5-16
0137-2475
2084-4158

Pojawia się w:

Studia Romanica Posnaniensia

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 24.

Tytuł:

Evaluation of neutrophil phagocytic, complement functions, and cytokines expression among diabetic patients in Abuja, Nigeria

Autorzy:

Babandina, Musa Muhammad
Mainasara, Abdullahi Suleiman
Bakare, Mustapha
Emeribe, Anthony Uchenna
Shuwa, Halima Ali
Haruna, Shamsuddeen
Muhammad, Aminu Said
Abdullahi, Idris Nasir

Powiązania:

https://bibliotekanauki.pl/articles/454973.pdf

Data publikacji:

2019

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

diabetes mellitus
effector molecules
pro-inflammatory markers

Opis:

Introduction. Inflammatory response in Diabetes Mellitus (DM) begins with chronic sub-clinical inflammations as a result of insulin resistance and activation of both innate and adaptive immune system as the disease progresses to complicated diabetes. Hence, the present study investigated the neutrophil phagocytic, complement function (CH50), and some cytokine profiles among diabetic and non-diabetic patients attending the National Hospital in Abuja, Nigeria. Aim. To evaluate the neutrophil phagocytic, complement function (CH50), and some cytokine profiles among post-operative septic diabetic and post-operative septic non-diabetic patients at the National Hospital in Abuja, Nigeria. Material and methods. Subjects were recruited by convenient sampling technique through interviewer-administered questionnaires. Subsequently, blood samples were collected. Fasting blood sugar (FBS) (mmol/L) was determined using glucose oxidase method. Neutrophil function test (Fmol/phag) was assayed using nitroblue tetrazolium reduction test (NBT). Hemolytic complement function (CH 50) test was conducted using serum harvested from sheep sensitized with human group (ORh D +ve) red blood cells. While serum Interleukin-4, -6, -10 and TNF- α were determined using Enzyme Linked Immunosorbent Assay (ELISA). Results. Mean ± Standard deviation (SD) of FBS concentration of 10.5 ± 1.3 (mmol/|L) among diabetic and 4.7 ± 0.9 (mmol/L) among non-diabetics was recorded. There is a decrease in neutrophil phagocytic function with a mean ± SD of 5.4 ± 2.1 (Fmol/ phag) in diabetics compared to 9.2 ± 2.1 (Fmol/phag) in non-diabetics. Similarly, complement (CH 50) function and C-reactive protein were significantly lower in diabetics when compared to non-diabetics (p<0.001). There was a significant difference in IL-6 concentration between diabetics and non-diabetics groups, but no significant difference was observed in TNF-α, IL-4 and IL-10 concentrations between study groups (p>0.05). TNF-α and IL-6 was significantly higher in diabetics with cardiovascular disorders compared to non-diabetics subjects with cardiovascular disorders (p<0.001). Conclusion. Findings from this study revealed the association of complement, neutrophil phagocytic function, CRP and IL-6 among septic diabetic patients,. In addition TNF-α and IL-6 expression was higher in DM patients with cardiovascular disorders.

Źródło:

European Journal of Clinical and Experimental Medicine; 2019, 3; 229-235
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 25.

Tytuł:

Role of biochemical factors in the pathogenesis of keratoconus

Autorzy:

Wojcik, Katarzyna
Blasiak, Janusz
Szaflik, Jerzy
Szaflik, Jacek

Powiązania:

https://bibliotekanauki.pl/articles/1039330.pdf

Data publikacji:

2014

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

keratoconus
cornea
collagen
proteinases
proinflammatory markers
antioxidants

Opis:

Keratoconus (KC) is a corneal disease associated with structural abnormalities in the corneal epithelium, Bowman's layer and stroma and altered concentration of tear components. KC corneas show a different pattern of collagen lamellae than their normal counterparts. Also, a reduction of several collagen types in KC epithelium and stroma was observed. Altered expression and/or activity of lysyl oxidase, a critical enzyme of the biogenesis of connective tissue detected in KC corneas, may weaken covalent bonds between collagen and elastin fibrils, what may lead to biomechanical deterioration of the cornea. Increased activity of matrix metalloproteinases observed in KC may induce the degradation of the extracellular matrix causing damage to the cornea. Oxidative and nitrative stress play an important role in KC pathogenesis and KC corneas are characterized by the disturbed lipid peroxidation and nitric oxide pathways. Malfunctioning of these pathways may lead to accumulation of their toxic by-products inducing several detrimental effects, along with apoptosis of the corneal cells, which may result from the loss of β-actin or increased levels of cytokines, including interleukin-1 and -6. Change in the expression of genes associated with wound healing, including the nerve growth factor and the visual system homeobox 1, may contribute to increased susceptibility of KC corneas to injury. Consequently, biochemical changes may play an important role in KC pathophysiology and, therefore, can be considered in prevention, diagnosis, prognosis and in the therapy of this disease as well.

Źródło:

Acta Biochimica Polonica; 2014, 61, 1; 55-62
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 26.

Tytuł:

Advanced oxidation protein products and inflammatory markers in liver cirrhosis: a comparison between alcohol-related and HCV-related cirrhosis

Autorzy:

Zuwała-Jagiełło, Jolanta
Pazgan-Simon, Monika
Simon, Krzysztof
Warwas, Maria

Powiązania:

https://bibliotekanauki.pl/articles/1039949.pdf

Data publikacji:

2011

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

advanced oxidation protein products
cirrhosis
inflammatory markers

Opis:

Advanced oxidation protein products (AOPPs) are protein markers of oxidative stress with pro-inflammatory properties that accumulated in liver cirrhosis. In the present study, we investigated the association between chronic inflammatory response triggered by AOPPs and the severity of liver disease as assessed by the Child-Pugh score. Plasma concentrations of AOPPs and inflammatory markers such as C-reactive protein, tumor necrosis factor-α, and interleukin-6 were measured in 41 patients with HCV-related cirrhosis, 43 patients with alcohol-related liver cirrhosis (ALC), and in 30 age and sex matched controls. In comparison with controls, AOPPs were increased in HCV-related compensated (Child-Pugh A) and decompensated (Child-Pugh B-C) cirrhosis and in alcohol-related compensated cirrhosis. AOPPs level positively correlated with Child-Pugh score in alcohol-related cirrhosis but not in HCV-related cirrhosis and the correlation with the indices of chronic inflammation was stronger in ALC. In turn, AOPPs in HCV-related cirrhosis was related to inflammation to a lesser extent, but a significant correlation with antioxidant defense could be noted. In summary, liver cirrhosis was associated with increased formation of AOPPs, which differed between alcohol-related and HCV-related cirrhosis with respect to the relationship between AOPPs and antioxidant defense, stage of liver cirrhosis, and inflammatory response. The significant correlation between AOPPs accumulation and indices of chronic inflammation, more specifically TNF-α, suggests that oxidative stress may be a mediator of chronic inflammatory state in the early stage of alcohol-related cirrhosis.

Źródło:

Acta Biochimica Polonica; 2011, 58, 1; 59-65
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 27.

Tytuł:

Application of the High Resolution Melting analysis for genetic mapping of Sequence Tagged Site markers in narrow-leafed lupin (Lupinus angustifolius L.)

Autorzy:

Kamel, Katarzyna
Kroc, Magdalena
Święcicki, Wojciech

Powiązania:

https://bibliotekanauki.pl/articles/1039001.pdf

Data publikacji:

2015

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

HRM
molecular markers
genotyping
narrow-leafed lupin

Opis:

Sequence tagged site (STS) markers are valuable tools for genetic and physical mapping that can be successfully used in comparative analyses among related species. Current challenges for molecular markers genotyping in plants include the lack of fast, sensitive and inexpensive methods suitable for sequence variant detection. In contrast, high resolution melting (HRM) is a simple and high-throughput assay, which has been widely applied in sequence polymorphism identification as well as in the studies of genetic variability and genotyping. The present study is the first attempt to use the HRM analysis to genotype STS markers in narrow-leafed lupin (Lupinus angustifolius L.). The sensitivity and utility of this method was confirmed by the sequence polymorphism detection based on melting curve profiles in the parental genotypes and progeny of the narrow-leafed lupin mapping population. Application of different approaches, including amplicon size and a simulated heterozygote analysis, has allowed for successful genetic mapping of 16 new STS markers in the narrow-leafed lupin genome.

Źródło:

Acta Biochimica Polonica; 2015, 62, 3; 533-540
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 28.

Tytuł:

Multiplexed Immunobead-Based Cytokine Profiling in patients with ovarian cancer

Autorzy:

Wyciszkiewicz, Aleksandra
Lach, Michał
Kalinowska, Alicja
Michalak, Sławomir
Nowakowski, Błażej

Powiązania:

https://bibliotekanauki.pl/articles/1890964.pdf

Data publikacji:

2021-12-02

Wydawca:

Gdański Uniwersytet Medyczny

Tematy:

ovarian cancer
cytokines
metalloproteinases
inflammation markers
endometriosis

Opis:

Due to late diagnosis, ovarian cancer is the most deadly gynecologic malignancy. Inflammation is one of the risk factors of ovarian cancer and the inflammatory response implicates all stages of tumorigenesis. The purpose of this study was to analyze the concentration of molecules, which can take part in malignant processes. We analyzed patients with ovarian cancer, with endometriosis and healthy controls. Thirty-seven analytes were measured in serum using BioPlex Pro Human Inflammation Panel. We were able to detect 28 of the proteins among the studied groups. We found a significant increase in 22 of the tested molecules (BAFF, Chitinase3-like 1, IFN-alpha2, IFN-beta, IFN-gamma, IFN-lambda2, IFN-lambda1, gp130, IL-2, IL-12 (p40), IL-11, IL-32, IL-35, MMP3, Osteocalcin, Pantraxin-3, sCD163, TNFRSF8, sIL-6Ralpha, STNF-R1, STNF-R2, and TSLP) in the ovarian cancer group in comparison to the healthy controls. Two of them (IL-20, MMP1) did not show significant differences between groups. Moreover, we identified decreased concentrations of APRIL and osteopontin in ovarian cancer vs. healthy controls. While this study is a preliminary report, we hope this will encourage a further use of multiplex analysis in ovarian cancer biomarker research.

Źródło:

European Journal of Translational and Clinical Medicine; 2021, 4, 2; 31-43
2657-3148
2657-3156

Pojawia się w:

European Journal of Translational and Clinical Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 29.

Tytuł:

The concentration of urea in hemolymph as a marker of health in Lissachatina fulica and Cornu aspersum edible snails – a preliminary study

Autorzy:

Ziętek, J.
Guz, L.
Wójcik, A.
Winiarczyk, S.
Adaszek, Ł.

Powiązania:

https://bibliotekanauki.pl/articles/2087559.pdf

Data publikacji:

2019

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

Lissachatina fulica
Cornu aspersum
hemolymph
urea
markers

Źródło:

Polish Journal of Veterinary Sciences; 2019, 2; 259-262
1505-1773

Pojawia się w:

Polish Journal of Veterinary Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 30.

Tytuł:

Study of antioxidant activity of liposomal forms of quercetin and curcumin in ischemic heart disease

Autorzy:

Pylypenko, D.
Gorbach, T.
Krasnopolsky, Y.

Powiązania:

https://bibliotekanauki.pl/articles/2096332.pdf

Data publikacji:

2020

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

curcumin
antioxidant
quercetin
liposomes
oxidative stress markers

Opis:

Quercetin and curcumin are plant polyphenolic antioxidants with proven pharmacological efficacy. Their use is, however, limited due to low bioavailability and oral administration route. The encapsulation of lipophilic compounds in liposomes enables to increase their bioavailability and to create an injectable form. The present study aimed to comparatively investigate the antioxidant activity of a complex liposomal preparation containing two lipophilic antioxidants (quercetin and curcumin) and their monopreparations in liposomal forms. This study was conducted on Wistar line rats with experimental model of ischemic heart disease. Oxidative stress markers such as total antioxidant activity, malondialdehyde, and peroxidized proteins were analyzed in blood serum and cardiac tissue. Ischemic heart disease is accompanied with lipid peroxidation and changes in the activity of the antioxidant system. The obtained results demonstrated the antioxidant activity of monopreparations of curcumin and quercetin and their complex in liposomal forms. Quercetin and curcumin showed different antioxidant activities in terms of oxidative stress markers. The complex of the two antioxidants showed the synergistic effect of their lipophilic compounds in liposomal forms, which led to the normalization of test parameters according to the level of the control sample.

Źródło:

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2020, 101, 4; 273-282
0860-7796

Pojawia się w:

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 31.

Tytuł:

The “Cow-mouth” Footwear from Coffin no. 7 in the Presbytery of the St Nicholas Church in Gniew (Poland)

Autorzy:

Kozłowski, Tomasz
Nowosad, Wiesław
Nalaskowski, Filip
Grupa, Dawid
Grupa, Małgorzata

Powiązania:

https://bibliotekanauki.pl/articles/38625899.pdf

Data publikacji:

2023

Wydawca:

Uniwersytet Rzeszowski. Instytut Archeologii Uniwersytetu Rzeszowskiego. Muzeum Okręgowe w Rzeszowie

Tematy:

Renaissance
footwear
markers
social differentiation
Gniew
Polska

Opis:

This article presents a comprehensive analysis of a pair of shoes excavated during archaeological research in the chancel of the St. Nicholas Church in Gniew, found on the feet of a man over 60. It is the first pair of Renaissance “cow-mouth” type shoes excavated from a grave. The results of the study of both archaeological material (footwear, velvet headgear covered with embroidery using threads in a metal braid) and iconography – portrait depictions, group scenes, and archival sources – confirmed the high social status of the deceased.

Źródło:

Analecta Archaeologica Ressoviensia; 2023, 18; 183-203
2084-4409

Pojawia się w:

Analecta Archaeologica Ressoviensia

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 32.

Tytuł:

Dispersal and immunohistochemical characteristics of neurons in the stem of the porcine vagus nerve

Autorzy:

Sienkiewicz, W.
Klimczuk, M.
Majewska, M.
Kaleczyc, J.

Powiązania:

https://bibliotekanauki.pl/articles/16647386.pdf

Data publikacji:

2022

Wydawca:

Polska Akademia Nauk. Czasopisma i Monografie PAN

Tematy:

vagus nerve
intravagal neurons
neurotransmitter markers
immunohistochemistry
pig

Opis:

The present study investigated the distribution and chemical properties of nerve cell bodies within the trunk of the vagus nerve in juvenile female pigs (n=4) using double-labelling immunofluorescence. The neurons appeared mostly as single cells or formed streaks of cells or small ganglia. Many of the perikarya were cholinergic (VAChT-positive; VAChT+) or adrenergic (DβH+) in nature and no SP+ or CGRP+ neurons were encountered. There were no distinct left-right differences regarding the number and chemical coding of the neuronal somata, however, these characteristics significantly varied between particular nerve segments investigated. The vagosympathetic trunks, and thoracic and abdominal segments of the vagus nerve contained on average (the numerical values represent the means for both the left and right corresponding nerve segments) 142, 236, and 111 PGP 9.5-positive neurons, respectively. Proportions of cholinergic and adrenergic neurons were as follows: 0% and 100%, 54.2% and 33.2%, and 52.8% and 35.4%, respectively. Relatively many neurons in the thoracic and abdominal segments stained also for NOS (39.2% and 39.9%, respectively). It remains to be determined whether the porcine intravagal neurons represent a developmental relic, or whether they have any specific functional significance.

Źródło:

Polish Journal of Veterinary Sciences; 2022, 25, 4; 617-619
1505-1773

Pojawia się w:

Polish Journal of Veterinary Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 33.

Tytuł:

Intensional profiles and different kinds of human minds. “Case studies” about Hungarian imperative-like sentence types

Autorzy:

Alberti, Gábor
Kleiber, Judit
Schnell, Zsuzsanna
Szabó, Veronika

Powiązania:

https://bibliotekanauki.pl/articles/1040189.pdf

Data publikacji:

2016-12-30

Wydawca:

Katolicki Uniwersytet Lubelski Jana Pawła II

Tematy:

discourse representation/markers
mind representation
dynamic pragmatics
autism

Opis:

The paper offers such description of some imperative-like sentence types in potential well-formed Hungarian utterances which includes a parallel representation of the linguistically encoded intensional profiles of the sentence types and actual information states in potential interlocutors’ minds. In our representational dynamic pragmasemantics framework ReALIS, we demonstrate the intensional profiles of the five basic and two “fine-tuned” sentence types as members of a system enabling addressers’ of utterances to express their beliefs, desires and intentions concerning the propositional content of the given utterances as well as the addressees’ and other people’s certain beliefs, desires and intentions (concerning the propositional content, too, or each other’s thoughts). We also provide “case studies” in which actual beliefs, desires and intentions in potential interlocutors’ minds are compared to the linguistically encoded intensional profiles of Hungarian imperative-like sentence types. In this context, the listener’s task is to calculate the speaker’s intentions (and hidden motives) on the basis of the mismatches that this comparison reveals. The paper concludes with an insight into our attempts to model the mind of individuals living with Autism Spectrum Disorder. This latter subproject is relevant since our framework provides solutions to pragmaticosemantic phenomena “at the cost” of undertaking the complex task of actually representing the structure of the human mind itself – which is not impossible but requires an adequate decision of the level of abstraction and the components to be used.

Źródło:

Linguistics Beyond and Within; 2016, 2; 6-26
2450-5188

Pojawia się w:

Linguistics Beyond and Within

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 34.

Tytuł:

Jajnik kury domowej (Gallus domesticus) w badaniach procesu nowotworzenia*
The hens (Gallus domesticus) ovary in studies on carcinogenesis

Autorzy:

Konieczny, Joanna
Grzesiak, Małgorzata

Powiązania:

https://bibliotekanauki.pl/articles/1034176.pdf

Data publikacji:

2017

Wydawca:

Polskie Towarzystwo Przyrodników im. Kopernika

Tematy:

cancer markers
functions
ovary
jajnik
funkcje
markery nowotworowe

Opis:

Nowotwór jajnika jest najgroźniejszym spośród nowotworów ginekologicznych, skutkującym wysoką śmiertelnością u kobiet. Zapadalność na niego zwiększa się z wiekiem i jest związana z częstotliwością owulacji. Zależność ta wskazuje na pochodzenie nowotworu z komórek nabłonka powierzchniowego jajnika, które ulegają ciągłym uszkodzeniom i regeneracji. Etiologia nowotworu jajnika jest jednak wciąż niejasna, dlatego jej szczegółowe poznanie jest niezbędne dla rozwoju strategii prewencyjnych, metod wczesnego wykrywania i leczenia. W ostatnich latach coraz częściej wykorzystuje się model kury domowej do badania procesu nowotworzenia w jajniku, ponieważ u ssaków nowotwór nie rozwija się spontanicznie z dużą częstotliwością. Ocena histopatologiczna różnych stadiów nowotworu jajnika kury potwierdziła jego wysokie podobieństwo do nowotworu ludzkiego, a szczegółowa charakterystyka molekularna wykazała ekspresję podobnych markerów nowotworowych, czynników immunologicznych oraz genetycznych. Kura domowa jako model doświadczalny daje nadzieję na poznanie procesów odpowiedzialnych za powstawanie i rozwój nowotworu jajnika u kobiet.
Ovarian cancer is one of the most lethal of gynecologic cancers in women. Its incidence is strongly correlated with the age and ovulation rate of patients. There are still various theories about the origin of ovarian cancer, so understanding of its etiology is vital for the development of prevention, early diagnosis and therapeutic strategies. Therefore, finding of a suitable animal model for further studies is a necessity. There is growing evidence that laying hen can be treated as the appropriate animal model, because among mammals ovarian cancer does not develop spontaneously with a sufficiently high frequency. Histopathological examinations of the chicken ovarian cancer have shown its remarkable resemblance to that of women's, while detailed molecular characterization have demonstrated expression of similar specific markers, immunological and genetic factors. The utility of laying hen as the experimental model may hopefully allow to deeper understand the processes underlying development of ovarian cancer in women.

Źródło:

Kosmos; 2017, 66, 2; 273-283
0023-4249

Pojawia się w:

Kosmos

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 35.

Tytuł:

Analysis of Polymorphic DNA Sequences in the Identfication of Individuals and its Possible Use in Biometric Systems

Autorzy:

Kartasińska, E.
Brągoszewska, A.

Powiązania:

https://bibliotekanauki.pl/articles/308733.pdf

Data publikacji:

2015

Wydawca:

Instytut Łączności - Państwowy Instytut Badawczy

Tematy:

DNA identifcation
DNA matching
genetic markers
genetic profiling

Opis:

The article presents the achievements in DNA forensic science practice, the latest developments as well as future trends. The article concerns also other than forensic DNA applications as well as expectations, concerns and obstacles. DNA identification technology unlike other biometric techniques requires the collection of biological material and the identification is not performed in real time. DNA utilized in most of forensic identification, is present almost in every living cell in the body. What is more, each cell of the same body has the same DNA molecule which means that it is possible to compare the DNA sampled from different sources, for example saliva with blood or semen from the same person. Rapid development and reliability of DNA technology contribute to the fact that the analysis of polymorphic DNA sequences constitutes a very important evidence used in the court. The unique properties of DNA and rapid development of DNA analytical devices allow to claim that DNA may assume a more important position amongst biometric data in the future.

Źródło:

Journal of Telecommunications and Information Technology; 2015, 2; 11-17
1509-4553
1899-8852

Pojawia się w:

Journal of Telecommunications and Information Technology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 36.

Tytuł:

Fast and cheap identification of elite aspen clones in the North-West of Russia using ISSR markers

Autorzy:

Zhigunov, Anatoly V.
Shabunin, Dmitrii A.
Butenko, Olesia Yu.
Lebedeva, Marina V.

Powiązania:

https://bibliotekanauki.pl/articles/2045732.pdf

Data publikacji:

2018

Wydawca:

Instytut Badawczy Leśnictwa

Tematy:

aspen
elite clones
molecular markers
ISSR
clonal plantations

Opis:

In 2001–2006, several experimental aspen plantations were established in the North-West of Russia (Leningrad region). Three in vitro propagated elite aspen (Populus tremula L.) clones from the Kostroma Forest Research Station were used as the planting stock for plantations. The planting plans of some experimental plantations were lost, which made it impossible to identify the genetic lineages. 13-years old unknown aspen clones demonstrated prominent growth rates, and reliably overtook natural aspen coppice. ISSR markers were used for fast and cheap restoring of the missing planting plan of the experimental aspen plantation under study; as a result, progenies of three elite aspen clones were recognized. The best fast-growing and stem rot resistant aspen clones was identified and called “Kostroma”.

Źródło:

Folia Forestalia Polonica. Series A . Forestry; 2018, 60, 4; 207-213
0071-6677

Pojawia się w:

Folia Forestalia Polonica. Series A . Forestry

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 37.

Tytuł:

Określenie wartości diagnostycznej wybranych badań immunohistochemicznych u chorych na mięsaki macicy w aspekcie ich przydatności terapeutycznej i prognostycznej
Determination of diagnostic value of selected immunohistochemical tests in patients with uterine corpus sarcoma and their therapeutic and prognostic usefulness

Autorzy:

Jońska-Gmyrek, Joanna
Nasierowska-Guttmejer, Anna
Bidziński, Mariusz
Dańska-Bidzińska, Anna

Powiązania:

https://bibliotekanauki.pl/articles/908070.pdf

Data publikacji:

2007

Wydawca:

Medical Communications

Tematy:

corpus uteri sarcoma
immunohistochemistry
markers
treatment
diagnosis
immunohistochemia

Opis:

Uterine sarcomas represent a rare and heterogenous group of tumours, sometimes demonstrating multidirectional differentiation. Histological type of the sarcoma influences the choice of therapeutic modality. Aim of paper: Determination of diagnostic value of selected immunohistochemical studies (MIB1, caldesmon, desmin, SMA, SrMa, CKAE1/3) in the definition of histological type of tumour. Assessment of expression of the protein c-kit (CD117) MIB1 and inhibin and their prognostic role. Material and method: Study material consisted of a group of patients with uterine sarcoma, treated at the Center of Oncology in Warsaw, Poland, since 1999 thru 2006, from whom surgical specimens and paraffin blocks were obtained. Of 120 eligible patients, complete clinical data and specimens suitable for foreseen studies were available in 66 cases and this group became the subject of further analyses. Immunohistochemical (IHC) tests were performed using a panel of antibodies (SMA, SrMa, desmin, h-caldesmon, CD10, CKAE, MIB1, inhibin and CD117). Diagnostic value of IHC studies was assessed by descriptive statistical tests. Original histopathological findings were confronted with the results of validated IHC tests. Survival was assessed based on Kaplan-Meier curves and follow-up time – by an inverse Kaplan-Meier curve. Prognostic factors were analysed by the Cox method. Threshold of statistical significance has been set at p=0.05. Results: Original microscopic findings have had to be modified as to histological type of sarcoma in about 1/3 of the cases. Histological diagnosis was an independent prognostic factor, influencing both overall survival rate and time to tumour recurrence. Prognostic factors influencing recurrence-free survival were: invasion of perivascular lymph space (lymph space invasion, LSI), proliferative index (MB1) and severity of tumour cell necrosis. Conclusions: Application of a panel of suitable IHC tests contributes to a more precise determination of tumour type, assisting in an optimal choice of adjuvant treatment modality and thus in improvement of the patients’ prognosis.
Mięsaki macicy stanowią rzadko występującą, heterogenną grupę nowotworów, wykazującą niekiedy wielokierunkowe różnicowanie. Typ histopatologiczny mięsaka ma wpływ na wybór metody leczenia. Cel: Określenie przydatności diagnostycznej wybranych badań immunohistochemicznych (MIB1, kaldesmon, desmi-na, SMA, SrMa, CKAE1/3) w ocenie typu histopatologicznego. Ocena ekspresji białka c-kit (CD117), MIB1, oraz inhibiny w aspekcie przydatności prognostycznej. Materiał i metoda: Materiał badawczy stanowiła grupa chorych na mięsaki macicy leczonych w Centrum Onkologii - Instytucie im. Marii Skłodowskiej--Curie w Warszawie w latach 1999-2006, od których uzyskano preparaty i bloczki parafinowe. Spośród 120 chorych pełne dane kliniczne i preparaty nadające się do zastosowania badań uzyskano od 66 chorych, która to grupa stała się przedmiotem analizy. Wykonano badania immunohistochemiczne z użyciem panelu przeciwciał: SMA, SrMa, desmina, h-kaldesmon, CD10, CKAE, MIB1, inhibina oraz CD117. Do oceny wartości diagnostycznej badań immunohistochemicznych (IHC) zastosowano statystykę opisową. Zestawiono wynik pierwotnego badania histopatologicznego z wynikiem zweryfikowanym badaniami IHC. Do oceny przeżycia zastosowano krzywą Kaplana-Meiera, czas obserwacji mierzono odwrotną metodą Kaplana-Me-iera. Do analizy czynników predykcyjnych zastosowano metodę Coksa. Istotność statystyczną określono na poziomie p=0,05. Wyniki: W stosunku do rozpoznania pierwotnego typ histopatologiczny mięsaków został zmieniony w około 1/3 przypadków. Rozpoznanie histopatologiczne okazało się niezależnym czynnikiem rokowniczym mającym wpływ zarówno na przeżycie ogólne, jak i czas do nawrotu choroby. Czynnikami rokowniczymi w aspekcie przeżycia bez nawrotu choroby okazały się: zajęcie naczyniowej przestrzeni chłonnej (LSI), indeks proliferacyjny (MIB1), oraz stopień martwicy w komórkach guza. Wnioski: Zastosowanie panelu odpowiednich badań immunohistochemicznych ma wpływ na precyzyjne określenie charakteru guza, co niesie za sobą wybór odpowiedniej metody leczenia uzupełniającego, a tym samym, być może poprawę rokowania.

Źródło:

Ginekologia Onkologiczna; 2007, 5, 2; 75-86
1731-5379

Pojawia się w:

Ginekologia Onkologiczna

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 38.

Tytuł:

O potrzebie, a nawet konieczności uwzględnienia infiksów w opisie polskiej fleksji werbalnej
On the necessity, or even obligation, to include infixes in the description of Polish verbal inflection

Autorzy:

Perlin, Jacek

Powiązania:

https://bibliotekanauki.pl/articles/568207.pdf

Data publikacji:

2013

Wydawca:

Uniwersytet Mikołaja Kopernika w Toruniu. Wydawnictwo UMK

Tematy:

morphology
affixes
infixes
verbal inflection
markers of aspect

Opis:

The aim of this paper is to present proof that infixes, being markers of the perspective aspect, exist in Polish verbal inflection. At the same time, it is demonstrated that some Polish, and more generally, Slavic affixes, constitute better examples of infixes than those that have been appearing in coursebooks and encyclopaedias of general linguistics so far. Moreover, it is suggested that there is a possibility of t includin infixes in descriptions of inflections of certain Germanic languages.

Źródło:

Linguistica Copernicana; 2013, 1(9); 203-213
2080-1068
2391-7768

Pojawia się w:

Linguistica Copernicana

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 39.

Tytuł:

Discourse Markers and Modal Expressions in Speakers with and without Asperger Syndrome: A Pragmatic-Perceptive Approach

Autorzy:

Muñoz, Francisco J. Rodríguez

Powiązania:

https://bibliotekanauki.pl/articles/620592.pdf

Data publikacji:

2014-03-01

Wydawca:

Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego

Tematy:

Asperger syndrome
discourse markers
modal expressions
perceptive pragmatics

Opis:

From a theoretical point of view, this paper offers a new framework for the analysis of discourse markers: a pragmatic-perceptive model that emphasizes the point of the communication process in which such particles become more relevant. Furthermore, this approach tries to give an account of the modal expressions (attenuators and intensifiers) that speakers use in oral speech. The quotients of absolute and relative frequency with regard to the use of textual, interactive and enunciative markers - focused on the message, the addressee and the addresser respectively - are compared in two samples of 20 subjects with typical development and other 20 with Asperger syndrome. The general results of this research suggest that these latter speakers display a suitable command of textual markers, whereas they overexploit the enunciative ones in conversation.

Źródło:

Research in Language; 2014, 12, 1; 1-25
1731-7533

Pojawia się w:

Research in Language

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 40.

Tytuł:

Persuasive functions of photo galleries on information websites

Autorzy:

Kampka, Agnieszka

Powiązania:

https://bibliotekanauki.pl/articles/650168.pdf

Data publikacji:

2017

Wydawca:

Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego

Tematy:

online gallery
rhetorical analysis
persuasion
coherence markers
narrativeness

Opis:

The article presents a rhetorical analysis of online galleries. The author argues that the selection of photographs presented in a gallery serves the purpose of fulfilling a persuasive goal. That is proved by, as indicated in the analysis, the verbal and visual markers of coherence, and the narrativeness visible at the level of individual photographs, groups of photographs, and the entire gallery.

Źródło:

Acta Universitatis Lodziensis. Folia Litteraria Polonica; 2017, 43, 5
1505-9057
2353-1908

Pojawia się w:

Acta Universitatis Lodziensis. Folia Litteraria Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 41.

Tytuł:

Zastosowanie markerów DNA w selekcji marchwi z cechą cytoplazmatycznej męskiej sterylności typu płatkowego
The use of DNA markers in the selection of carrot lines with cytoplasmic male sterility trait

Autorzy:

Szczechura, W.
Nowakowska, M.
Nowak, K.
Kamiński, P.
Nowak, R.
Kozik, E.U.

Powiązania:

https://bibliotekanauki.pl/articles/2119577.pdf

Data publikacji:

2019

Wydawca:

Instytut Ogrodnictwa

Tematy:

CMS
carrot
DNA markers
marker-assisted selection (MAS)

Opis:

Cytoplasmic male sterility (CMS) is a maternally inherited trait in which a plant is unable to produce functional pollen. It occurs in many plants, including carrots. The expression of this trait depends on environmental conditions, especially temperature – therefore, DNA markers become an excellent tool for selecting carrot genotypes with this feature. In this study, we used seventeen DNA markers available in the literature, linked with various mitochondrial DNA sequences that are associated with the CMS trait. Their amplification was tested on male sterile and male fertile plants. Only five markers – A321/392, I214/401/435, K751, N795, O790 – correctly identified the tested genotypes. They can be used as selection tools in carrot breeding programs.

Źródło:

Zeszyty Naukowe Instytutu Ogrodnictwa; 2019, 27; 53-62
2300-5882
2391-8969

Pojawia się w:

Zeszyty Naukowe Instytutu Ogrodnictwa

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 42.

Tytuł:

Genetic variation of safflower (Carthamus tinctorius L.) and related species revealed by ISSR analysis

Autorzy:

Bagmohammadi, Hamed
Pahlevani, Mohammadhadi
Ahmadikhah, Asadollah
Razavi, Seyed Esmaeil

Powiązania:

https://bibliotekanauki.pl/articles/2199709.pdf

Data publikacji:

2012-08-20

Wydawca:

Instytut Hodowli i Aklimatyzacji Roślin

Tematy:

Genetic diversity
ISSR markers
relationships
safflower
wild spices

Opis:

Genetic diversity of eight genotypes of Carthamus tinctorius L., two populations of C. oxyacanthus, and one population of C. lanatus was investigated using inter-simple sequence repeat (ISSR) markers. All samples were uniquely distinguished by 10 ISSR primers with 144 bands which generated 100% polymorphism. Furthermore, the ISSR markers could separate three safflower species properly, that highlights the effectiveness of this marker system for phylogenetic studies. The most and least informative primers were ISSR9 (PIC=0.367) and ISSR2 (PIC=0.254), and some primers were more efficient in detecting polymorphism in one species than for the others. Unweighed pairgroup method with arithmetical averages (UPGMA) cluster analysis enabled construction of a dendrogram  for estimating genetic distances among different populations. The result of cluster analysis suggested that cultivated and wild populations of C. oxyacanthus had close relationship with each other and far relationship with C. lanatus. The extreme genetic dissimilarity was observed between genotypes of C. tinctorius and C. lanatus populations. Based on the results, C. oxyacanthus could introduce favorable genes to cultivated safflower via inter-specific hybridization in breeding programs. Nei’s gene diversity index, Shannon’s index and percent of polymorphic loci showed that Isfahan ecotype of C. oxyacanthus had the highest variation at DNA level in relation to populations of other species. The ISSRs developed in this research along with those recently studied by other researchers will contribute to construct genetic map with a density sufficient for safflower molecular breeding.

Źródło:

Plant Breeding and Seed Science; 2012, 66; 139-150
1429-3862
2083-599X

Pojawia się w:

Plant Breeding and Seed Science

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 43.

Tytuł:

In situ genetic variability and micropropagation of Cerastium banaticum (Rochel) Heuff. (Caryophyllaceae)– a rare and endemic species from Romania

Autorzy:

Cristea, V.
Besenyei, E.
Jarda, L.
Farkas, A.
Marcu, D.
Clapa, D.
Halmagyi, A.
Butiuc-Keul, A.

Powiązania:

https://bibliotekanauki.pl/articles/2117879.pdf

Data publikacji:

2019

Wydawca:

Polska Akademia Nauk. Czasopisma i Monografie PAN

Tematy:

acclimatization
biodiversity conservation
plant growth regulators
SSR markers

Opis:

Rare and endemic plant species represent important components of plant biodiversity which require protection to ensure their sustainable conservation. Cerastium banaticum (Rochel) Heuff. is such an endemic and rare species from Romania, for which the genetic variability of two natural populations was studied by SSR markers. Shannon’s information index revealed low levels of genetic diversity in both populations (I = 0.296). As the first attempt in a conservation program a reproducible micropropagation protocol was established starting from seeds, followed by multiplication, rooting, and ex vitro acclimatization. Among the various plant growth regulators tested the highest multiplication coefficient was achieved on a culture medium with 0.5 mg L -1 6-furfurylaminopurine (K) and 1 mg L -1 α-naphthaleneacetic acid (NAA). On this PGRs concentration a number of 26.6 shoots/individual explant with a mean length of 7.9 cm for new generated shoots was registered. The highest number of roots/indi- vidual initiated shoot was 2.6 and it was recorded on a culture medium with 0.5 mg L -1 2-isopentyl-adenine (2iP) and 0.1 mg L -1 NAA. The outdoor acclimatization was successfully performed in a specially designed rocky area in the ‘Alexandru Borza’ Botanical Garden, Cluj-Napoca (Romania).

Źródło:

Acta Biologica Cracoviensia. Series Botanica; 2019, 61, 1; 53-62
0001-5296

Pojawia się w:

Acta Biologica Cracoviensia. Series Botanica

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 44.

Tytuł:

The dynamics of biochemical markers of enzymoemia and middle-weight molecules in the early post-traumatic period of brain injury

Autorzy:

Ziablitsev, S. V.
Elskyy, V. N.
Pischulina, S. V.
Strelchenko, U. I.
Antonov, E. V.
Sudilovskaya, U. L.
Khudoley, S. A.

Powiązania:

https://bibliotekanauki.pl/articles/1032378.pdf

Data publikacji:

2014

Wydawca:

Uniwersytet Kazimierza Wielkiego w Bydgoszczy

Tematy:

brain injury
biochemical markers
enzymoemia
middle-weight molecules

Opis:

In the experimental model of brain injury (BI) markers of enzymoemia (aminotransferases ALT and AST, alkaline and acid phosphatase (AlP and AcP), cathepsin D (CD)) and middle-weight molecules (MWM) were estimated. 3 hours after trauma there were increase of all enzymes that evidences about damage of cytoplasmic (ALT, AST, AlF) and lysosomal membranes (AcP, CD). During period of observation different dynamics of enzymatic changes occurred: plateau phase for ALT and CD and progressive increase of concentration with the maximum on the 5th day of the experiment for AlP and AcP. Increase of the level of MWM displayed the development of endogenous intoxication in the post-traumatic period. Relation between particular components of MWM was studied. It was shown that primary accumulation of nucleotide fraction and aromatic peptides is adverse factor of the course of post-traumatic period, development of endotoxicosis, and multiorgan failure.

Źródło:

Journal of Health Sciences; 2014, 4, 1; 297-302
1429-9623

Pojawia się w:

Journal of Health Sciences

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 45.

Tytuł:

Similarities and differences between two Hungarian particles for also: szintén and is

Autorzy:

Farkas, Judit
Futó, Bettina
Huszics, Aliz
Kleiber, Judit
Dóla, Mónika
Alberti, Gábor

Powiązania:

https://bibliotekanauki.pl/articles/1040294.pdf

Data publikacji:

2020-12-30

Wydawca:

Katolicki Uniwersytet Lubelski Jana Pawła II

Tematy:

particles
distributive meaning
Hungarian
pragmatic and discourse markers

Opis:

The paper provides a comparative analysis of the syntax, semantics and pragmatics of two Hungarian particles with the same logical core meaning also: is and szintén. The analysis yields important theoretical implications since it demonstrates how two particles sharing the same logical-propositional/truth-functional core meaning can expand into two different markers. In discourse, is acts as an intensional/metacognitive pragmatic marker in the sense as proposed by Aijmer et al. (2006), while szintén functions as a coherence-signaling discourse marker. The two particles share certain syntactic-semantic properties: neither of them can be followed by a topic, they both have distributive meaning, and both of them can pertain to the noun phrase that they immediately follow, as well as to ordered n-tuples of noun phrases. However, there are also syntactic and pragmasemantic differences between them. Namely, their ordered n-tuples have different word orders; is can function as a pragmatic marker while szintén cannot; szintén can appear as a separate clause, while is cannot (this is presumably related to the fact that szintén can be stressed, while is is obligatorily unstressed); and finally, szintén can have a peculiar discourse-preserving function. We explain the syntactic differences between the two particles using the partial spell-out technique of minimalist generative syntacticians (first applied to Hungarian by Surányi 2009), and the Cinque-hierarchy-based approach to Hungarian sentence- and predicate-adverbials (Surányi 2008). We account for the pragmasemantic properties of the pragmatic-marker variant of is in the formal representational dynamic theory of interpretation called ReALIS, already presented in the LingBaW series (Alberti et al. 2016, Kleiber and Alberti 2017, Viszket et al. 2019).

Źródło:

Linguistics Beyond and Within; 2020, 6; 74-91
2450-5188

Pojawia się w:

Linguistics Beyond and Within

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 46.

Tytuł:

Hybridity of a plant created in a combination of crossing of (Vaccinium uliginosum L. × V. vitis-idaea L.) × Oxycoccus macrocarpus (Aiton) Pursh at the tetraploid level

Autorzy:

Marozau, Aleh
Baranov, Oleg Yu.

Powiązania:

https://bibliotekanauki.pl/articles/2045745.pdf

Data publikacji:

2018

Wydawca:

Instytut Badawczy Leśnictwa

Tematy:

consecutive crossing
DNA markers
Ericaceae
hybridisation
sequencing
tetraploids

Opis:

The aim of the study was to determine the hybridity of the F1 generation of Vaccinium cf. uliginosum × V. vitis-idaea × Oxycoccus macrocarpus created through the consecutive crossing of some common berry species of the family Ericaceae (bog whortleberry, cowberry and marsh cranberry) at the tetraploid level. Certain aspects of phenology and morphometric parameters of vegetative organs of the supposed hybrid and parent plants were analysed using traditional methods of comparative analysis. Molecular genetic assay, including random amplification of polymorphic DNA, simple sequence repeat and sequencing, were also used. Comparison of the phenological and morphometric features of the experimental plant and its parents allows suggesting that in the combination of crossing of (V. uliginosum × V. vitis-idaea) × O. macrocarpus (the cultivar Searles), a three-species hybrid was created. The allelic variants, specific for V. uliginosum, V. vitis-idaea and O. macrocarpus, were detected in the V. cf. uliginosum × V. vitis-idaea × O. macrocarpus genotype. A next-generation sequencing approach is suggested for estimating the share of the genomes of Vaccinium spp. in the formation of the interspecies hybrid.

Źródło:

Folia Forestalia Polonica. Series A . Forestry; 2018, 60, 4; 281-291
0071-6677

Pojawia się w:

Folia Forestalia Polonica. Series A . Forestry

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 47.

Tytuł:

The usage and meaning of "mentioned" ("wspomniany") and "described" ("opisany") metatext markers in Polish scientific texts

Autorzy:

Czoska, Agnieszka

Powiązania:

https://bibliotekanauki.pl/articles/677036.pdf

Data publikacji:

2018

Wydawca:

Polska Akademia Nauk. Instytut Slawistyki PAN

Tematy:

metatext
metatext markers
scientific text
cloze-test
Polish

Opis:

The usage and meaning of mentioned (wspomniany) and described (opisany) metatext markers in Polish scientific textsMetatext markers (MMs) are defined as expressions used in a text to inform readers of its structure or relations between its elements (Fraser, 1999; Goldman & Rakestraw, 2000; Schiffrin, 1988). In this paper the usage of two MMs "mentioned" ("wspomniany") and "described" ("opisany") in scientific texts is described and the relation between their meaning and usage is analysed. In Study 1, the frequency, scope and direction of the MM is analysed in a corpus of peer-reviewed scientific texts in Polish. In Experiment 2, participants decided whether to use the aforementioned MMs to fill gaps in short scientific texts. The results of both experiments suggest that while the meaning of an MM may influence its usage, this relation may be affected by the size of the whole text. Użycie i znaczenie operatorów metatekstowych wspomniany i opisany w tekstach naukowych po polskuOperatory metatekstowe (OM) to wyrażenia informujące czytelnika o strukturze tekstu, w którym zostały umieszczone, oraz o relacjach pomiędzy jego elementami (Fraser, 1999; Goldman & Rakestraw, 2000; Schiffrin, 1988). W poniższej pracy zostało opisane użycie dwóch OM wspomniany i opisany w tekstach naukowych, przeanalizowano także relację pomiędzy ich znaczeniem i używaniem. W badaniu 1 zostały przeanalizowane częstość użycia, zakres i ukierunkowanie OM w tekstach naukowych pisanych po polsku. W badaniu 2 czytelnicy decydowali o tym, czy umieścić dodatkowy OM w krótkim tekście naukowym. Wyniku obydwu badań wskazują, że znaczenie OM może wpływać na sposób jego używania, ale wpływ ten zmienia się wraz z wielkością tekstu.

Źródło:

Cognitive Studies; 2018, 18
2392-2397

Pojawia się w:

Cognitive Studies

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 48.

Tytuł:

Dependence of Aerobic Performance of Athletes on Polymorphism of Genes

Autorzy:

Drozdovska, Svitlana B.
Lysenko, Olena M.
Dosenko, Victor E.
Ilyin, Vladimir N.

Powiązania:

https://bibliotekanauki.pl/articles/1055065.pdf

Data publikacji:

2015

Wydawca:

Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego

Tematy:

aerobic performance
gene polymorphisms
molecular-genetic markers
sport selection

Opis:

The adaptation of an athlete to systematic physical exercise has been shown to be determined by a combination of great many genes. The aim of our study was to investigate the dependence of the aerobic capacity parameters in sport on the set of gene polymorphisms. Cardio-respiratory system (CRS) adaptation reactions to exercise of 72 endurance athletes were assessed using the gas analysis. The analysis of the obtained results has shown both single and combined effect of the gene polymorphisms on the aerobic capacity. The impact of 6 polymorphisms on the aerobic performance level was analyzed: Т–786→С polymorphism of the promoter of еNOS gene as well as АСЕ I/D polymorphism, Рго/Ala polymorphism of PPARG gene, G/C polymorphism of PPARA gene, Pro582Ser polymorphism of HIF1α gene, and Ala203Pro polymorphism of PPARGC1B. It was found that a single impact on the HRmax providing АСЕ I/D polymorphism. Individual influence of АСЕ gene accounts for 2% of this index dissipation. Results showed that there is a dependence between the amount the maximum volume of consumed oxygen (VO2max) from the set of gene polymorphisms. Cumulative impact of these polymorphisms in the combination with the individual parameters (gender; qualification; kind of sport) stipulates 71% of dispersion of VO2max value.

Źródło:

Central European Journal of Sport Sciences and Medicine; 2015, 9, 1; 65-73
2300-9705
2353-2807

Pojawia się w:

Central European Journal of Sport Sciences and Medicine

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 49.

Tytuł:

Cytochrome P4502C9 genotype in Southeast Anatolia and possible relation with some serum tumour markers and cytokines.

Autorzy:

Yılmaz, Necat
Erbağcı, Ayşe
Aynacioğlu, A

Powiązania:

https://bibliotekanauki.pl/articles/1044109.pdf

Data publikacji:

2001

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

CYP2C9 polymorphism
Anatolia
cytokines
tumour markers

Opis:

Substrates for CYP2C9 include fluoxetine, phenytoin, warfarin, losartam and numerous nonsteroidal anti-inflammatory drugs. Polymorphisms in the coding region of the CYP2C9 gene produce variants at amino-acid residues 144 Arg/Cys and 359 Ile/Leu of the CYP2C9 protein. Individuals homozygous for Leu359 have markedly diminished metabolic capacities for most CYP2C9 substrates, the frequency of this allele is, however, rather low. Consistently with the modulation of enzyme activity by genetic and other factors, wide interindividual variability occurs in the elimination and/or dosage requirements of prototypic CYP2C9 substrates. The polymorphic enzyme CYP2C9 takes part in the metabolism of alkylating agents and polycyclic aromatic hydrocarbons like benzo(a)pyrene, a carcinogen present in tobacco smoke. Although the impact of impaired enzyme activity in metabolism of carcinogens and procarcinogens has not been fully defined, an association of CYP2C9 variant alleles to DNA adduct levels in lung tissues as well as to lung cancer risk have been reported. In this study 64 healthy subjects (44M/22F) were analysed for CYP2C9 genotype with PCR-RFLP and for serum carcinoembryonic antigen (CEA), α-fetoprotein (AFP), CA 19-9, CA 15-3, ferritin, IL-6, IL-8 concentrations by chemiluminescence or electrochemiluminescence methods. CYP2C9*1 was found to be the most prevalent allele and CYP2C9*1/CYP2C9*1 was the most frequent genotype represented in 64% of the population in southeastern Anatolia (Gaziantep). Although slight differences in serum tumour marker and cytokine concentrations were observed for CYP2C9 genotypes the differences were statistically insignificant (P >0.05). This could be due to the complexity of the role of CYP2C9 in benzo(a)pyrene metabolism as well as from other contributing factors like interindividual variability of diverse enzymes participating in the same metabolic pathway, unequal expression of the variant alleles and differences in exposure to carcinogens. However, determination of CYP2C9 phenotypes in a larger group of subjects might clarify these slight differences.

Źródło:

Acta Biochimica Polonica; 2001, 48, 3; 775-782
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 50.

Tytuł:

PRAGMATIC MARKER USE IN POLICE INTERVIEWS: THE CASE OF I MEAN AND YOU KNOW (PART 2)

Autorzy:

Szczyrbak, Magdalena

Powiązania:

https://bibliotekanauki.pl/articles/634599.pdf

Data publikacji:

2014

Wydawca:

Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego

Tematy:

comment clauses, police interview discourse, power relations, pragmatic markers

Opis:

Intended as a follow-up to Part 1 of the study focusing on the use of I mean in police interview data, Part 2 of the analysis offers insight into the recruitment of the related marker you know by the interviewers and the interviewees, respectively. In particular, acknowledging that the primary function of you know is that of “inviting addressee inferences” (Jucker, Smith 1998) and in agreement with the categorisation of functions proposed by Fox Tree and Schrock (2002), the paper reveals how you know is deployed for interpersonal, turn management, repairing, monitoring and organising purposes. To this end, it focuses on the syntactic behaviour of you know and examines the patterns of use linked to individual interview participants. What is more, given the potential of you know to invite addressee feedback, the analysis also looks at listener responses to you know and you know-introduced ideas, revealing at the same time the linguistic coding of power asymmetry in institutional interaction. In sum, Part 1 and Part 2 of the study highlight the subjective and intersubjective meanings conveyed by the markers I mean and you know in police interviews and draw attention to the contribution that pragmatic marker research can make to court and police interpreting practice.

Źródło:

Studia Linguistica Universitatis Iagellonicae Cracoviensis; 2014, 131, 4
2083-4624

Pojawia się w:

Studia Linguistica Universitatis Iagellonicae Cracoviensis

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 51.

Tytuł:

Discourse markers in non-native EFL teacher talk

Autorzy:

Vickov, Gloria
Jakupčević, Eva

Powiązania:

https://bibliotekanauki.pl/articles/780467.pdf

Data publikacji:

2017

Wydawca:

Uniwersytet im. Adama Mickiewicza w Poznaniu

Tematy:

discourse markers
non-native (Croatian) EFL teachers
classroom discourse

Opis:

The present study aims to investigate the use of discourse markers (DMs) in non-native (Croatian) EFL teachers´ talk with primary and secondary school students. The study concentrates on the occurrences and frequencies of DMs, but it also provides an account of the function distribution of the three most frequently used DMs (ok, so, and). The quantitative and qualitative analyses of the recorded transcriptions reveal that the teachers use a variety of DMs, almost exclusively the ones typical of classroom management and classroom discourse organization, with no significant differences in the patterns of DM use with the primary and secondary school students. The DMs fulfill a number of structural and interpersonal functions mainly aimed at providing coherent and stimulating classroom discourse. The findings of this study might contribute to raising awareness of the diversified functions of DMs, which could facilitate non-native EFL teachers´ overall lesson organization and structuring of particular teaching segments.

Źródło:

Studies in Second Language Learning and Teaching; 2017, 7, 4; 649-671
2083-5205
2084-1965

Pojawia się w:

Studies in Second Language Learning and Teaching

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 52.

Tytuł:

Introduction of Fatigue Markers in Full Scale Fatigue Test of an Aircraft Structure

Autorzy:

Leski, A.
Kłysz, S.
Lisiecki, J.
Gmurczyk, G.
Reymer, P.
Bochenek, D.
Zasada, D.

Powiązania:

https://bibliotekanauki.pl/articles/97777.pdf

Data publikacji:

2012

Wydawca:

Sieć Badawcza Łukasiewicz - Instytut Lotnictwa

Tematy:

full scale fatigue test
fatigue markers
load block rearrangement

Opis:

Air Force Institute of Technology participates in the service life assessment programme SEWST. The aim of this programme, funded by the Polish Ministry of Defense, is to modify the operation system of PZL-130 "Orlik" TC-II turbo propelled trainer aircraft. The structural part of the programme is focused on the Full Scale Fatigue Test of the whole airframe to be conducted at the VZLU in the Czech Republic. The load spectrum for the test was developed by the AFIT based on the flight test results. The basic load block represents 200 simulated flight hours and consists of 194 flights showing different levels of severity. At the end of the Full Scale Fatigue Test a teardown inspection is planned during which it would be most beneficial to be able to determine crack propagation rate by means of a crack surface inspection. Markers are usually visible on most fatigue crack surfaces, however they occur randomly therefore it is almost impossible to conclude anything about the crack history. Since the preliminary load block consisted of separate flights (flight loads together with landing and taxing loads) showing significantly different levels of severity, the easiest way to modify the load block was to change the order of flights within the block. Hence a pilot programme was started at the AFIT which was focused on the determination of the influence of flight sequence on crack appearance. Several load blocks were determined using various techniques of rearranging the order of flights within the preliminary load spectrum. This approach ensured the preservation of the initial severity of the load block and simultaneously enabled a significant increase in the probability of the markers occurrence introducing neither artificial underloads nor overloads that would most probably affect the crack propagation rate. Fatigue crack surfaces were inspected using Scanning Electron Microscope. As a result of the investigations a series of images were obtained showing the specimen microstructure with visible markers arranged in the desired sequences. Based on the obtained pictures the most promising load block arrangements were chosen for the Full Scale Fatigue Test.

Źródło:

Fatigue of Aircraft Structures; 2012, 4; 29-37
2081-7738
2300-7591

Pojawia się w:

Fatigue of Aircraft Structures

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 53.

Tytuł:

Pragmatic marker use in police interviews: The case of I mean and you know (Part 1)

Autorzy:

Szczyrbak, Magdalena

Powiązania:

https://bibliotekanauki.pl/articles/634377.pdf

Data publikacji:

2014

Wydawca:

Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego

Tematy:

comment clauses, police interview discourse, power relations, pragmatic markers

Opis:

Drawing on interactional approaches to comment clauses (Stenström 1994; Povolná 2010), the paper reveals the discourse functions of I mean (Part 1) and you know (Part 2) in the context of police interviews. More specifically, taking into account the socio-pragmatic setting of police-suspect interaction, it highlights the context-dependence and the multifunctionality of these markers based on data from two police interview transcripts. Thus, following the spirit of the study by Fox Tree and Schrock (2002), Part 1 of the analysis demonstrates that while the primary role of I mean is that of “forewarning upcoming adjustments” (Schiffrin 1987), the marker performs interpersonal, turn management, repairing, monitoring and organizing functions. This being the case, the study examines the potential of I meanm to modify the ongoing interaction and stresses its contribution to the coherence of the interviewees’ narratives. Attention is also drawn to the syntactic environment in which I mean occurs as well as to listener responses to I mean and I mean-introduced ideas. Finally, the discussion touches upon the issue of power relations and shows the role which I mean plays in the linguistic manifestation of power in an institutional setting.

Źródło:

Studia Linguistica Universitatis Iagellonicae Cracoviensis; 2014, 131, 3
2083-4624

Pojawia się w:

Studia Linguistica Universitatis Iagellonicae Cracoviensis

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 54.

Tytuł:

Interval mapping of genes controlling growth of rye plants

Autorzy:

Milczarski, Paweł
Masojć, Piotr

Powiązania:

https://bibliotekanauki.pl/articles/2198924.pdf

Data publikacji:

2003-12-21

Wydawca:

Instytut Hodowli i Aklimatyzacji Roślin

Tematy:

QTLs
growth
genetic map
molecular markers
Secale cereale L.

Opis:

The F2-type population derived from the cross between DS2 and RXL1O inbred lines was used for interval mapping of five growth related traits i.e. plant height, spike length, thousand grain weight, kernel length and kernel thickness. Scanning of the whole 1,140 cM length of rye genetic map consisting of 286 marker loci revealed the existence of 6 regions containing QTL5 on chromosomes 1R-5R. Plant height was strongly affected by 1-3 linked dwarfing genes from a distal region of the chromosome 5RL and by 1 gene on the chromosome 3RL, tightly linked to a marker loci Xpsr4 75. These same genes regulated also thousand grain weight and kernel length and thickness. Spike length was determined only by the QTL from chromosome 5RL. In addition a single QTL from chromosome 2R affecting thousand grain weight and kernel thickness was identified, near the molecular marker locus Xrsq8OS. 1. Kernel length and kernel thickness were additionally controlled by QTL5 on chromosomes 2R and 1R and 4R, respectively.

Źródło:

Plant Breeding and Seed Science; 2003, 48; 135-142
1429-3862
2083-599X

Pojawia się w:

Plant Breeding and Seed Science

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 55.

Tytuł:

Population genetic structure of Iris pumila L. in Ukraine: effects of habitat fragmentation

Autorzy:

Bublyk, O.
Andreev, I.
Parnikoza, I.
Kunakh, V.

Powiązania:

https://bibliotekanauki.pl/articles/2117815.pdf

Data publikacji:

2020

Wydawca:

Polska Akademia Nauk. Czasopisma i Monografie PAN

Tematy:

conservation
genetic polymorphism
habitat fragmentation
ISSR markers
population
genetics

Opis:

Habitat fragmentation is one of serious threats to biodiversity of nature in today's world. The present study of a typical steppe species Iris pumila L. (Iridaceae) has analyzed the impacts of geographical isolation and population size on genetic diversity and population structure in conditions of habitat fragmentation. The key indices of population genetic variability calculated from the ISSR markers data were on average as follows: Shannon diversity index (S) – 0.188; unbiased Nei’s gene diversity (He ) – 0.123; and the average measure of Jaccard’s genetic distances between individuals within populations – 58.4%. Although the largest population had significantly higher values of S and He, the small and marginal populations also showed a comparable level of variation. Most of the genetic variation of I. pumila was distributed within the populations. A strong correlation was found between Nei’s genetic distances and geographic distances between the populations. According to the Bayesian analysis, genetic structure of the populations was highly homogeneous; however, the presence of admixed genotypes indicated the possibility of gene flow between the populations at present.

Źródło:

Acta Biologica Cracoviensia. Series Botanica; 2020, 62, 1; 51-61
0001-5296

Pojawia się w:

Acta Biologica Cracoviensia. Series Botanica

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 56.

Tytuł:

Genetic polymorphism of Hucul horse population based on 17 microsatellite loci

Autorzy:

Fornal, Agnieszka
Radko, Anna
Piestrzyńska-Kajtoch, Agata

Powiązania:

https://bibliotekanauki.pl/articles/1039481.pdf

Data publikacji:

2013

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

microsatellite markers
STR
parentage testing
horse
Hucul horse
indigenous breeds

Opis:

Short tandem repeat (STR) loci, i.e. microsatellites are a class of genetic markers commonly used for population studies and parentage control. This study determined the usefulness of microsatellite markers recommended by International Society for Animal Genetics (ISAG) for identification and pedigree analysis in horses based on the example of Polish Hucul horse population (Equus caballus). The set of seventeen microsatellites loci was tested (AHT4, AHT5, ASB2, HMS2, HMS3, HMS6, HMS7, HTG10, HTG4, HTG6, HTG7, VHL20, ASB17, ASB23, CA425, HMS1, LEX3) for 216 individuals. All samples were genotyped and mean number of alleles per locus was estimated (7.00). Means of observed (Ho) and expected (He) heterozygosity were calculated 0.7288 and 0.7027, respectively. The observed heterozygosity was similar to the results of research on Hucul horse population in another area of Carpathians Mountains. The average polymorphism information content (PIC) for analyses of seventeen microsatellite markers indicates the usefulness of this set of markers for Hucul horse parentage testing.

Źródło:

Acta Biochimica Polonica; 2013, 60, 4; 761-765
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 57.

Tytuł:

Environmental factors influencing the development of atherosclerosis
Czynniki środowiskowe wpływające na rozwój miażdżycy

Autorzy:

Brodziak, Andrzej
Brewczyński, Piotr Z.

Powiązania:

https://bibliotekanauki.pl/articles/1177841.pdf

Data publikacji:

2013

Wydawca:

Instytut Medycyny Wsi

Tematy:

environmental factors
lifestyle
novel markers of atherosclerosis
pathogenesis of atherosclerosis

Opis:

The aim of the paper is to present an overview of recent findings on the environmental and behavioral factors influencing the development of atherosclerosis. The authors primarily concentrated on deliberations of possibile main causes of the damage of the endothelium. At the same time the following pathogenic mechanisms as cellular dysfunction, inflammation and coagulation disorders have been enumerated. The links between the state of the vascular endothelium and life style have been emphasized. It is also important to note that the primary causes of the endothelial damage should be traced as originally suggested many years ago viewing such factors as anger, hostility, aggression, impulsiveness and depression but with a new approach. The authors supplement the comments, on the environmental factors influencing the development of atherosclerosis, with basic data on family predisposition to the development of this disease. They highlight that current genetic research have not determined genes responsible for atheroscelosis. According to the authors the considerations and conclusions presented in this overview are important for the educational purposes related to the most frequent disease process resulting in many diseases in medical disciplines.
Celem pracy jest dokonanie przeglądu najnowszych ustaleń dotyczących czynników środowiskowych i behawioralnych biorących udział w powstawaniu i patogenezie miażdżycy. Tym samym, jakkolwiek wymieniono w niej takie mechanizmy patogenetyczne jak zaburzenia funkcji makrofagów, procesy zapalne i zaburzenia krzepnięcia, to jednak autorzy skoncentrowali się przede wszystkim na rozważeniu możliwych pierwotnych przyczyn uszkodzenia śródbłonka naczyń. Podkreślono powiązania pomiędzy jego stanem a stylem życia. Istotnym jest zwrócenie uwagi na fakt, że poszukując pierwotnych przyczyn uszkodzenia śródbłonka należy ponownie – lecz z użyciem nowego warsztatu – rozważyć rolę zaproponowanych, już wiele lat temu, czynników osobowościowych i behawioralnych, a wśród nich wrogość, agresywność, impulsywność czy depresję. Komentarze o środowiskowych czynnikach wpływających na rozwój miażdżycy uzupełniono ponadto danymi na temat predyspozycji rodzinnej do powstawania tego procesu chorobowego. Podkreślono, że dotychczasowe badania genetyczne nie określiły krytycznych chorobotwórczych wariantów genów, co skłoniło autorów do tymczasowego sformułowania o „braku wyznaczników dziedziczności”. Przedstawione rozważania mają zdaniem autorów znaczenie dla uzupełnienia procesu dydaktycznego dotyczącego tego najbardziej rozpowszechnionego procesu chorobowego skutkującego licznymi jednostkami chorobowymi w wielu dyscyplinach medycznych.

Źródło:

Medycyna Środowiskowa - Environmental Medicine; 2013, 16, 4; 7-15
1505-7054
2084-6312

Pojawia się w:

Medycyna Środowiskowa - Environmental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 58.

Tytuł:

ProCESSES OF ETHNIC IDENTITY FORMATION AMONG DESCENDANTS OF IMMIGRANTS. THE CASE OF THE COMMUNITIES OF BUENOS AIRES AND THE MISIONES PROVINCE (ARGENTINA)

Autorzy:

PORADA, Katarzyna

Powiązania:

https://bibliotekanauki.pl/articles/556129.pdf

Data publikacji:

2016

Wydawca:

Uniwersytet Warszawski. Instytut Studiów Iberyjskich i Iberoamerykańskich

Tematy:

Descendants of Immigrants
Ethnic Identity
Ethnic Markers
Poles in Argentina

Opis:

Polish community in Argentina – along with the community in Brazil – is one of the most numerous Polishorigin communities in Latin America. Seventy years have passed since the migratory processes between Poland and Argentina practically came to a halt, and the temporal distance since the arrival of the last group of Poles to this country is now reflected in the gradual and inevitable disappearance of the majority of these immigrants. Today, their adult descendants, who were born (many in exogamic families), raised and educated in Argentina, continue with a variety of activities that attempt, in one way or another, to keep the Polish culture alive. These activities, however, do not take shape in a vacuum or independently from the context surrounding particular groups; on the contrary, they are constructed in constant interaction with the receiving society and with the rest of the groups. In this article, based on the specific case of the Polish community in Buenos Aires and in the Misiones Province (Argentina), we intend to analyze the particularities

Źródło:

Ameryka Łacińska. Kwartalnik analityczno-informacyjny; 2016, 24, 4(94); 25-42
1506-8900
2081-1152

Pojawia się w:

Ameryka Łacińska. Kwartalnik analityczno-informacyjny

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 59.

Tytuł:

Identification of AFLP markers linked with low-temperature resistance in introgressions transferred from Festuca arundinacea to Lolium multiflorum.

Autorzy:

Pawlowicz, Izabela
Rapacz, Marcin
Bocianowski, Jan

Powiązania:

https://bibliotekanauki.pl/articles/2199162.pdf

Data publikacji:

2008-12-21

Wydawca:

Instytut Hodowli i Aklimatyzacji Roślin

Tematy:

AFLP markers
freezing resistance
F. arundinacea
L. multiflorum
winter hardiness

Opis:

BC3-152/53 population of L. multiflorum plants comprising single introgression of F. arundinacea genome was tested for low-temperature tolerance. 13.8% of individuals were more freezing-resistant, whereas 16.25% had higher winter hardiness than control L. multiflorum plants. AFLP analysis were performed resulting in generation of 19 markers linked with freezing resistance, 7 linked with winter hardiness and 2 markers correlated with both traits. It indicates that Festuca introgression could make the impact on Lolium stress resistance...

Źródło:

Plant Breeding and Seed Science; 2008, 58; 3-10
1429-3862
2083-599X

Pojawia się w:

Plant Breeding and Seed Science

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 60.

Tytuł:

Analiza podobieństwa genetycznego wybranych gatunków w rodzaju Secale
The analysis of genetic similarity among Secale species

Autorzy:

Broda, Zbigniew
Kurasiak-Popowska, Danuta
Kowalska, Aleksandra
Ćwiklińska, Anna

Powiązania:

https://bibliotekanauki.pl/articles/41446083.pdf

Data publikacji:

2008

Wydawca:

Instytut Hodowli i Aklimatyzacji Roślin

Tematy:

markery RAPD
podobieństwo genetyczne
żyto
RAPD markers
genetic similarity
rye

Opis:

Przedmiotem badań była analiza podobieństwa genetycznego form dzikich z rodzaju Secale. Materiałem roślinnym były gatunki żyta: Secale cereale subsp. afghanicum, Secale cereale subsp. dighoricum, Secale cereale subsp. segetale, Secale strictum subsp. africanum. Secale strictum subsp. anatolicum, Secale strictum subsp. ciliatoglume, Secale strictum subsp. kuprijanovii, Secale strictum, Secale sylvestre oraz Secale vavilovii. Analiza prążków RAPD pozwoliła na wytypowanie starterów generujących polimorficzne prążki, pozwalające zróżnicować badane gatunki i podgatunki z rodzaju Secale. Przeprowadzone badania pozwoliły na podział roślin na trzy grupy o różnym stopniu podobieństwa genetycznego. Wieloletnie gatunki z rodzaju Secale utworzyły jedną grupę podobień- stwa, a gatunki jednoroczne dwie grupy, w których podobieństwo wynosiło od 11 do 21%.
The aim of this study was the analysis of genetic similarity among Secale species. The plant material included: Secale cereale subsp. afghanicum, Secale cereale subsp. dighoricum, Secale cereale subsp. segetale, Secale strictum subsp. africanum, Secale strictum subsp. anatolicum, Secale strictum subsp. ciliatoglume, Secale strictum subsp. kuprijanovii, Secale strictum, Secale sylvestre and Secale vavilovii. Based on the RAPD (random amplified polymorphic DNA) analysis primers generating polymorphic products were selected, which made possible to differentiate species and subspecies of Secale. Three groups of the Secale species were distinguished according to the different degree of genetic similarity. Perennial species were classified in one group of similarity, and annual species in two groups, in which the similarity ranged from 11 to 21%.

Źródło:

Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin; 2008, 247; 65-71
0373-7837
2657-8913

Pojawia się w:

Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 61.

Tytuł:

Wykorzystanie markerów RAPD do oceny zróżnicowania genotypowego polskich odmian pszenżyta ozimego
The application of RAPD markers to estimation of genotypic diversity of Polish winter triticale cultivars

Autorzy:

Kramek, Aneta

Powiązania:

https://bibliotekanauki.pl/articles/41455912.pdf

Data publikacji:

2008

Wydawca:

Instytut Hodowli i Aklimatyzacji Roślin

Tematy:

markery RAPD
pszenżyto
zróżnicowanie genotypowe
genotypic diversity
RAPD markers
triticale

Opis:

Celem pracy była ocena zróżnicowania genotypowego 22 polskich odmian pszenżyta ozimego za pomocą markerów RAPD. Ocenę polimorfizmu międzyodmianowego przeprowadzono w oparciu o 15 starterów RAPD, które zostały wyselekcjonowane spośród 48 wstępnie testowanych na pięciu genotypach pszenżyta ozimego. Wybrane oligonukleotydy amplifikowały łącznie 135 fragmentów DNA, z których 87 (64,44%) było polimorficznych. Wartość indeksów podobieństwa genetycznego wynosiła średnio 0,862 i wahała się od 0,734 pomiędzy odmianami Malno i Tewo do 0,903 między odmianami Marko i Fidelio. Największy dystans genetyczny w stosunku do pozostałych odmian stwierdzono u odmiany Tewo (0,785), a najbardziej podobną do wszystkich odmian okazała się odmiana Fidelio (0,855). Na podstawie przeprowadzonych badań stwierdzono niewielkie zróżnicowanie genotypowe analizowanych odmian pszenżyta ozimego.
The aim of this study was estimation of genotypic diversity of 22 Polish winter triticale cultivars based on RAPD markers. The estimation of intercultivar polymorphism was carried out basing on 15 RAPD primers, which were selected among 48 primers tested on 5 winter triticale genotypes. The chosen oligonucleotides generated 135 fragments of DNA, 87 of them (64.44%) were polymorphic. The mean value of similarity index was 0.862 and fluctuated from 0.734 between cv. Malno and cv. Tewo to 0.903 between cv. Marko and cv. Fidelio. The highest average genetic distance to all examined cultivars was observed in the cv. Tewo (0.785), the cv. Fidelio was the most similar to other cultivars. On the base of obtained results a low level of genotypic diversity was stated among the studied winter triticale cultivars.

Źródło:

Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin; 2008, 248; 43-51
0373-7837
2657-8913

Pojawia się w:

Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 62.

Tytuł:

Lexikální prostředky a styl nové české literatury
Lexical Devices and the Style of the New Czech Literature

Autorzy:

Mareš, Petr

Powiązania:

https://bibliotekanauki.pl/articles/615665.pdf

Data publikacji:

2017

Wydawca:

Uniwersytet Opolski

Tematy:

archaism
colloquialism
lexical devices
literary text
poetism
stylistic markers
vulgarism

Opis:

The paper deals with the complexity of stylistic markers of words and with the employment of these markers for aesthetic purposes and effects in several works of modern Czech literature. There is a distinctive tendency in the Czech prose to combine lexical devices with dissimilar, often antagonistic stylistic markers (formal and colloquial, archaic and new, polite and vulgar etc.). The main part of the paper includes short analyses of selected texts that operate with lexical devices in such a way. In 1920s, Vladislav Vanèura was a pioneer of this stylistic technique. In the last decades, novels and short stories by Ota Pavel, Jiøí Gruša or Petra Hùlová represent outstanding examples of achieving significant effects by contrasting words with antagonistic stylistic markers.

Źródło:

Stylistyka; 2017, 26; 173-181
1230-2287
2545-1669

Pojawia się w:

Stylistyka

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 63.

Tytuł:

Dydaktyczny model pojazdu autonomicznego sterowanego znacznikami
Didactic model of autonomous vehicle controlled with markers

Autorzy:

Koziej, A.
Kułakowski, A.

Powiązania:

https://bibliotekanauki.pl/articles/253504.pdf

Data publikacji:

2016

Wydawca:

Instytut Naukowo-Wydawniczy TTS

Tematy:

model pojazdu autonomicznego
sterowanie znacznikami
autonomous vehicle model
control markers

Opis:

W artykule omówiony został problem konstruowania i oprogramowania dydaktycznego modelu pojazdu autonomicznego sterowanego przy pomocy znaczników. Zaprezentowano konstrukcję pojazdu. Opisano architekturę oprogramowania sterującego i rozpoznającego znaczniki, oraz problem planowania ruchu pojazdu. Przeprowadzono testy ruchowe pojazdu oraz szybkości przetwarzania informacji sterujących.
The paper presents the problem of constructing and programming an autonomous vehicle model controlled with markers. The construction of the vehicle has been presented. There has been described architecture of control and recognition marker software as well as the problem of planning the vehicle motion. There have been carried out tests of vehicle mobility and speed of control information processing.

Źródło:

TTS Technika Transportu Szynowego; 2016, 12; 375-380
1232-3829
2543-5728

Pojawia się w:

TTS Technika Transportu Szynowego

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 64.

Tytuł:

Analysis of molecular markers as IL-12, IL-22 and IFN-γ in correlation with a clinical course in patients with psoriasis

Autorzy:

Kutwin, Magdalena
Migdalska-Sęk, Monika
Brzeziańska-Lasota, Ewa
Zelga, Piotr
Woźniacka, Anna

Powiązania:

https://bibliotekanauki.pl/articles/2116535.pdf

Data publikacji:

2020-09-17

Wydawca:

Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi

Tematy:

psoriasis
disease activity
proinflammatory cytokines
skin disease
immunology
molecular markers

Opis:

ObjectivesAs a chronic, recurrent, immunologically mediated systemic disease and a common cause of dermatological problems, psoriasis is often a subject of scientific research. Skin changes located on the hands can cause difficulties and limitations in the performance of professional activities, especially manual ones. The main role in pathogenesis is played by immunological factors – improper functioning of the components of the immune system, among others, T lymphocytes and cytokines like interleukin-12 (IL-12), interleukin-22 (IL-22) and interferon gamma (IFN-γ).Material and MethodsThe obtained tissue and blood were destined for RNA isolation. The RNA was then subjected to a reverse transcription reaction. The relative gene expression level was evaluated by the real-time polymerase chain reaction for IL-12B, IL-22 and IFN-γ genes, and presented as the relative quantification (RQ) value, relative to the reference gene GAPDH. In addition, a correlation analysis of the expression level of selected genes with the clinical course of the disease, as assessed by the Psoriasis Area and Severity Index (PASI), the Body Surface Area (BSA) and the Dermatology Life Quality Index (DLQI) scores was performed.ResultsStatistical analysis confirmed a significant increase in RQ values for IL-12B, IL-22 and IFN-γ in the group of psoriatic patients vs. the control group. A positive correlation was also found between BSA and PASI and RQ for the IL-12B gene.ConclusionsIncreased expression levels of IL-12B, IL-22 and IFN-γ genes in psoriatic skin confirm that selected cytokines play an important role in the initiation and sustenance of psoriasis.

Źródło:

International Journal of Occupational Medicine and Environmental Health; 2020, 33, 5; 635-647
1232-1087
1896-494X

Pojawia się w:

International Journal of Occupational Medicine and Environmental Health

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 65.

Tytuł:

New directions in molecular diagnostics and therapy of vestibular schwannomas

Autorzy:

Litwiniuk, Malgorzata
Makuszewska, Maria
Bartoszewicz, Robert
Niemczyk, Kazimierz

Powiązania:

https://bibliotekanauki.pl/articles/1399284.pdf

Data publikacji:

2020

Wydawca:

Index Copernicus International

Tematy:

acoustic neuroma
bevacizumab
biological treatment
microRNAs
prognostic markers
vestibular schwannoma

Opis:

The molecular basis for the formation and growth of vestibular schwannomas (VS) has been elucidated in the recent years. The main genetic and epigenetic aberrations, changes in gene expression and specific signaling pathways involved in pathogenesis of sporadic VS and neurofibromatosis type II (NF2) have been defined. These findings facilitated the search for prognostic markers in VS and potential targets for biological therapy. This publication summarizes the main directions of research in the field of molecular diagnostics and pharmacotherapy of VS based on biological agents.

Źródło:

Polski Przegląd Otorynolaryngologiczny; 2020, 9, 4; 55-59
2084-5308
2300-7338

Pojawia się w:

Polski Przegląd Otorynolaryngologiczny

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 66.

Tytuł:

Using SSR markers for assessment genetic diversity and detection drought escape candidate genes in barley lines (Hordeum vulgare L.)

Autorzy:

Gougerdchi, Vahideh
Dezhsetan, Sara
Ebrahimi, Mohammad Ali
Sadeghzadeh, Behzad
Savari, Sona

Powiązania:

https://bibliotekanauki.pl/articles/2199609.pdf

Data publikacji:

2014-12-18

Wydawca:

Instytut Hodowli i Aklimatyzacji Roślin

Tematy:

Association analysis
barley
genetic diversity
Microsatellite markers (SSR)
drought escape

Opis:

Assessment of genetic diversity using molecular markers is one of the primary and important steps in breeding programs. In this study, genetic diversity of 52 barley lines evaluated using 68 SSR primer pairs and 47 primer pairs produced clear and polymorphic banding pattern. In general, 153 polymorphic alleles de-tected. The number of observed polymorphic alleles varied from 2 to 9, with an average of 3.26 alleles per locus. Polymorphic Information Content (PIC) ranged from 0.07 to 0.81, with an average of 0.45. In this research, SSR markers differentiated the studied lines efficiently. Using cluster analysis, studied barley lines divided into two groups. Genetic diversity was relatively corresponding with geographical origins, because the lines related to a country somewhat diverged from each other. Two-rowed Iranian and Chinese barleys classified in one subgroup. Also, most six-rowed barleys classified in one subgroup. Association mapping analysis was used to identify candidate genes for drought escape in barley lines and 16 informative markers were identified after which confirmation in other tests could be suitable for marker assisted breeding drought escape.

Źródło:

Plant Breeding and Seed Science; 2014, 70; 3-14
1429-3862
2083-599X

Pojawia się w:

Plant Breeding and Seed Science

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 67.

Tytuł:

Neurolinguistic and acoustic study of logopenic Primary Progressive Aphasia in Arabic

Autorzy:

Taiebine, Mohamed
El Alaoui Faris, Mustapha

Powiązania:

https://bibliotekanauki.pl/articles/2106027.pdf

Data publikacji:

2019-12-18

Wydawca:

Fundacja Edukacji Medycznej, Promocji Zdrowia, Sztuki i Kultury Ars Medica

Tematy:

neurolinguistic
primary progressive aphasia
atypical AD
logopenic
acoustic markers
Arabic

Opis:

The primary progressive aphasia (PPA) or Mesulam syndrome is an isolated and progressive deterioration of language, usually due to progressive focal atrophy of the left peri sylvian regions. Given that very little data on PPA is available in non-Western languages in the literature, we describe the first case of logopenic PPA in Arabic. Neuropsychological, neuroimaging and linguistic protocol have been administered to the patient. The Neurolinguistic assessment was carried out with the Moroccan version of the Montreal-Toulouse linguistic exploration protocol, the apraxia of speech protocol, the Moroccan version of MLSE (Mini-Linguistic Status Examination); some subtests of the BDAE (Boston Diagnostic Aphasia Examination) while the computerized acoustic analysis was performed with Vocalab4 ™. The acoustic analysis showed mainly instability in pitch and amplitude. However articulatory disruptions are very mild in our case. There is a parallelism between spoken language which is marked by phonological paraphasias with a „pseudostuttering „and written language disorder which displays a phonological alexia, a severe acalculia and an agraphia. Our pa tient presents L-PPA subtype 1 on the logopenic spectrum. These results are consistent with the neuropsychological hypothesis of a dysfunction in phonological buffer reflecting the features of logopenic PPA. Furthermore, our case displayed atypical neurolinguistic patterns in comparison with other cases described in the European languages due to the Arabic specific linguistic structure.

Źródło:

Acta Neuropsychologica; 2019, 17(4); 469-485
1730-7503
2084-4298

Pojawia się w:

Acta Neuropsychologica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 68.

Tytuł:

HISTORY OF THE DATIVE MARKERS IN KOREAN LANGUAGE: FROM OLD KOREAN TO CONTEMPORARY KOREAN
한국어 여격조사의 역사: 고대한국어에서부터 현대한국어까지
Historia sposobu wyrażania celownika w języku koreańskim: od starokoreańskiego do współczesnego koreańskiego

Autorzy:

BAILBLÉ, Olivier

Powiązania:

https://bibliotekanauki.pl/articles/1040346.pdf

Data publikacji:

2016-11-04

Wydawca:

Uniwersytet im. Adama Mickiewicza w Poznaniu

Tematy:

Datives Markers
Early Middle Korean
Chinese Characters
Idu Writing System

Opis:

The focus of this paper and the intention of the author are to show in a diachronic perspective how the dative markers in Korean Language have changed and evolved during two thousand years of history. The rise of new writing systems during 8th century such as Idu and also the difference of the structure of the language between Chinese and Korean bring different conclusions. In particular, this paper will focus on the different grammatical origins of dative markers and additionally the morphological changes will be shown in those structures, especially with the rise of the Korean Alphabet in 15th century.
이 연구는 한국어 여격의 변화를 통시적 관점에서 다루고 있다. 이천 년 전 한국인들은 외국에서 온, 다시 말해 한자를 사용하기 시작하였다. 풍부하지 않은 자료로 첫 번째 여격의 초기형태를 엿보기 위해서는 5 세기 광개토대왕의 비문을 참고해야만 한다. 하지만 광개토왕의 비문의 글은중국어 문법에 따라 한자어로 쓰여 있어 문장에 대한 판독은 쉽지 않다. 바로 이러한 이유로 그 시대부터 한국사람들은 전통적인 한자어 구조를 한국어의 구조에 맞게 변경하기 시작하였다. 이러한 변화는 이두 표기법 (관료들의 문자) 의 출현에서 엿볼 수 있다. 이두 표기법은 고대의 텍스트에 존재하지 않은 한국어의 문법적인 형태를 재현해주고 있다. 게다가 12 세기경에는 우리는 이두 표기법의 여격에서 분명하게 이 변화를 알아볼 수 있다. 한편 이두 표기법은 훈민정음 창제로 또 다른 중요한 발전을 맞이하게 된다. 이두 표기법으로 표현된, 중국어의 차용으로 표기된 조사는 대다수 한글로 대체되어 사라지게 된 것이다. 여격 또한 이 변화에 예의 없이 원래의 기원과는 많이 달라진 형태를 보여준다. 유교사상의 결합으로 생긴 사회계층에 의한 높임말에 변화에 따라 여격의 변화가 생기는 것이다. 이러한 기원은 우리가 누구와 대화하느냐에 따라 다르게 표현되는 현대 한국어에서 쉽게 찾아볼 수 있다.

Źródło:

International Journal of Korean Humanities and Social Sciences; 2015, 1; 119-136
2449-7444

Pojawia się w:

International Journal of Korean Humanities and Social Sciences

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 69.

Tytuł:

Changes in oxidative stress markers in plasma of sows during periparturient period

Autorzy:

Szczubiał, M.

Powiązania:

https://bibliotekanauki.pl/articles/2087316.pdf

Data publikacji:

2020

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

oxidative stress markers
lipid and protein peroxidation
periparturient period
plasma
sows

Źródło:

Polish Journal of Veterinary Sciences; 2020, 23, 2; 185-190
1505-1773

Pojawia się w:

Polish Journal of Veterinary Sciences

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 70.

Tytuł:

Viability and genetic diversity of Populus nigra population from riparian forest in SNR Gornje Podunavlje

Autorzy:

Čortan, Dijana
Tubić, Bojan

Powiązania:

https://bibliotekanauki.pl/articles/956812.pdf

Data publikacji:

2017

Wydawca:

Polska Akademia Nauk. Instytut Dendrologii PAN

Tematy:

black poplar
viability assessment
genetic diversity
ssr markers
snr upper danube

Opis:

Populus nigra L. is one of the rarest and most endangered tree species in Western and Central Europe. Its genetic diversity is of great importance in enabling a native riparian population to survive and reproduce under changing environmental conditions. The aim of this research was assessment of P. nigra viability in one of the best preserved riparian ecosystems in Europe, Special Nature Reserve “Gornje Podunavlje” (Upper Danube), Serbia. Additionally, the analysis of the genetic diversity was made to support the effective conservation in the future. During our study, we have mapped 931 P. nigra trees, which were used for the assessment of present native population. Furthermore, we used 14 microsatellite markers to assess the genetic structure of this this population. Viability assessment showed considerable occurrence of P. nigra in the research area, even though the results show fragmentation. P. nigra occurs mostly individually or in small groups of trees, and has a non-sustainable age structure due to insufficient or lacking regeneration. Despite the limited size of the studied population, the apparent overall genetic diversity was high (He = 0.759) and comparable to other known native populations of P. nigra along the Danube basin. However, the results also confirmed existence of recent bottleneck effect. Significantly positive and quite high Fis value (0.147) was noted, which may be ascribed to the “Wahlund effect” because of the population substructure that was revealed by the STRUCTURE analysis (K=2). Although results say that coverage of native stands is not so promising, most of selected trees within our research assessed showed good viability with potential for natural reproduction However, the problem is that suitable areas for natural seedling establishment are scarce and with that gene flow is probably limited. The fragmentation of the area must be reduced and isolated stands must be interlinked as there is need to create larger non-fragmented areas.

Źródło:

Dendrobiology; 2017, 78; 157-167
1641-1307

Pojawia się w:

Dendrobiology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 71.

Tytuł:

La subjetivización y las dinámicas interaccionales
Subjectification and interactional dynamics

Autorzy:

Baran, Marek

Powiązania:

https://bibliotekanauki.pl/articles/1050939.pdf

Data publikacji:

2014-01-01

Wydawca:

Uniwersytet im. Adama Mickiewicza w Poznaniu

Tematy:

subjectification
pragmaticalization
interactional linguistics
conversational markers
ethnolects
Spanish language
face-work

Opis:

In the present article the subjectification process is being discussed in relation to the concept of interactional dynamics. It is suggested that to encode various semantic-pragmatic profiles can lead to changes at the level of communicative behavior patterns, which, for their part, are dominated by a particular order of socio-cultural conventionalization. The scope of conversational markers or nominal forms of address (NFA), which are submitted to analysis in the present study, indicates that the routinizing language use, together with an explicit grammatical manifestation, covers areas that appear to be semantically and pragmatically important in a given speaking community.

Źródło:

Studia Romanica Posnaniensia; 2014, 41, 1; 3-16
0137-2475
2084-4158

Pojawia się w:

Studia Romanica Posnaniensia

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 72.

Tytuł:

Health risk in road transport workers. Part I. Occupational exposure to chemicals, biomarkers of effect

Autorzy:

Gromadzińska, Jolanta
Wąsowicz, Wojciech

Powiązania:

https://bibliotekanauki.pl/articles/2161975.pdf

Data publikacji:

2019-06-14

Wydawca:

Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi

Tematy:

drivers
occupational exposure
markers of occupational exposure
inflammation
Oxidative stress
chemicals

Opis:

Motor vehicle emissions constitute a mixture of different chemicals: volatile organic solvents, polycyclic aromatic hydrocarbons, heavy metals, isocyanates, etc. Drivers working in car cabins are exposed to chemicals deriving from incomplete combustion of fuels, exhaust emissions from working engines and fuel evaporation. Concentrations of these substances are rather low and do not exceed the applicable hygiene standards, but some of them pose, or are suspected to pose, carcinogenic risk. The interaction of chemical substances with human cells and tissues can lead to a number of modifications of metabolic pathways at a cellular level. The first biological mechanism of metabolic modulation is an inflammatory state and oxidative stress generation. The aim of this review is to analyze biomarkers of effect and to assess the hazard of occupational exposure of drivers. Int J Occup Med Environ Health. 2019;32(3):267–80

Źródło:

International Journal of Occupational Medicine and Environmental Health; 2019, 32, 3; 267-280
1232-1087
1896-494X

Pojawia się w:

International Journal of Occupational Medicine and Environmental Health

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 73.

Tytuł:

Zastosowanie metod RAPD i ISSR do oceny podobieństwa genetycznego greckich form Dasypyrum villosum (L.) P. Candargy
Application of RAPD and ISSR methods to genetic similarity estimation of Greek Dasypyrum villosum (L.) P. Candargy populations

Autorzy:

Grądzielewska, Agnieszka
Paczos-Grzęda, Edyta
Gruszecka, Daniela

Powiązania:

https://bibliotekanauki.pl/articles/42809908.pdf

Data publikacji:

2009

Wydawca:

Instytut Hodowli i Aklimatyzacji Roślin

Tematy:

Dasypyrum
ISSR
RAPD
markery molekularne
podobieństwo genetyczne
genetic similarity
molecular markers

Opis:

W pracy przeprowadzono ocenę podobieństwa genetycznego 9 greckich form Dasypyrum villosum L. (P.) Candargy pochodzących z trzech regionów Grecji (Tesalii oraz Zachodniej i Środkowej Macedonii) na podstawie polimorfizmu markerów RAPD i ISSR. Analizę podobieństwa genetycznego przeprowadzono z wykorzystaniem 18 wyselekcjonowanych starterów RAPD i 17 starterów ISSR. Ogółem otrzymano 122 fragmenty RAPD i 210 ISSR, z czego 50% było polimorficznych. Technika RAPD pozwoliła na identyfikację produktów specyficznych jedynie u pięciu z dziewięciu badanych form, podczas gdy przy udziale metody ISSR otrzymano takie fragmenty dla siedmiu populacji, najwięcej dla W6 7264. Dla obu zastosowanych w badaniach metod obliczono współczynnik informacji o polimorfizmie (PIC), którego wartość zawierała się w przedziale 0,13–0,68 dla RAPD i 0,15–0,52 dla ISSR, średnio odpowiednio 0,32 i 0,33. Na podstawie polimorfizmu markerów RAPD i ISSR oraz obu technik łącznie obliczono wartości indeksów podobieństwa genetycznego Dice’a, pomiędzy parami badanych populacji. Średnie podobieństwo badanych obiektów wyniosło odpowiednio 0,854, 0,871 i 0,864. Najbardziej odmienną od pozostałych była forma W6 7264. W oparciu o matryce podobieństw Dice’a skonstruowano dendrogramy obrazujące stosunki pokrewieństwa pomiędzy badanymi populacjami.
Estimation of genetic similarity between nine Greek Dasypyrum villosum L. (P.) Candargy populations native to three Greece regions (Thesally, West and Central Macedonia) was performed basing on polymorphism of RAPD and ISSR markers. Eighteen RAPD and seventeen ISSR selected primers were used in the genetic similarity analyses. In total, 122 RAPD and 210 ISSR products were obtained, out of which 50% were polymorphic. The RAPD method identified specific products only in five from nine populations studied, while ISSR in seven, most for W6 7264. Polymorphic information content (PIC) values calculated for the both methods, ranged from 0.13–0.68 for RAPD and 0.15–0.52 for ISSR. Mean values of PIC for RAPD and ISSR were 0.32 and 0.33, respectively. Based on the polymorphism of RAPD and ISSR markers and both methods combined, genetic similarities using Dice algorithm were estimated between pairs of populations analyzed. Mean genetic similarities were 0.854, 0.871 and 0.864, respectively. Most different from the others was W6 7264. Based on Dice matrix similarities, dendrograms showing relatedness between the analyzed populations were constructed.

Źródło:

Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin; 2009, 253; 297-307
0373-7837
2657-8913

Pojawia się w:

Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 74.

Tytuł:

Zróżnicowanie genetyczne linii wsobnych kukurydzy a plonowanie odmian mieszańcowych
Genetic distance among inbred lines of maize and its association with hybrid performance

Autorzy:

Rogacki, Janusz
Bulińska-Radomska, Zofia
Dzienkiewicz, Jakub
Adamaczyk, Józef
Cygert, Henryk

Powiązania:

https://bibliotekanauki.pl/articles/42821662.pdf

Data publikacji:

2009

Wydawca:

Instytut Hodowli i Aklimatyzacji Roślin

Tematy:

markery molekularne
plon mieszańców
Zea mays L.
hybrid performance
molecular markers,

Opis:

Celem pracy była ocena zróżnicowania genetycznego 10 linii wsobnych o ziarnie zębokształtnym (dent) i 7 linii o ziarnie szklistym (flint) kukurydzy w relacji do plonowania 70 mieszańców eksperymentalnych powstałych w wyniku czynnikowego układu krzyżowania „dent × flint”. Do oceny zróżnicowania genetycznego 17 linii wsobnych kukurydzy użyto markerów RAPD generowanych w oparciu o technikę PCR. Do powielania znaczników (markerów) wykorzystano 12 semi-specyficznych 18.-nukleotydowych starterów. Wyliczenie wartości współczynnika dystansu genetycznego Nei’a pomiędzy poszczególnymi badanymi liniami zostało przeprowadzone w oparciu o 404 polimorficzne fragmenty DNA. Wartości współczynników dystansu genetycznego wyliczono wg metody Nei & Li (1979). Większość wykorzystanych starterów generowała obrazy z wysokim udziałem fragmentów polimorficznych. Wartości współczynników dystansu genetycznego uzyskane dla par linii były stosunkowo wysokie i zawierały się w przedziale od 0,29 do 0,72. Analiza skupień przeprowadzona metodą średnich połączeń (UPGMA) wartości współczynników dystansu genetycznego dała podstawę do wyodrębnienia trzech różniących się między sobą grup linii kukurydzy; dwóch w obrębie linii o ziarnie zębokształtnym oraz jednej wspólnej dla linii szklistych. Średnia wartość współczynnika dystansu genetycznego w obrębie linii zębokształtnych wyniosła 0,56, natomiast w obrębie linii szklistych 0,46. Regresja plonów 70 mieszańców (dent × flint) względem dystansu genetycznego linii rodzicielskich tworzących ich formuły, wskazuje na bardzo słaby związek obu cech. Reasumując, przedstawiona metoda jest bardziej przydatna do poprawnego zaszeregowania linii do właściwej grupy heterotycznej niż do prognozowania wysokości plonu ziarna mieszańca na podstawie dystansu genetycznego pomiędzy liniami rodzicielskimi.
The main objective of the present study was to evaluate the genetic diversity of 17 (10 dent and 7 flint) inbred lines of maize in relation to yield performance of 70 hybrids produced according to North Carolina II design “dent × flint”. To assess genetic divergence among 17 inbred lines, random amplified polymorphic DNA (RAPD) molecular markers were used. Twelve different, primers consisting of 18 nucleotides were used to produce a total of 404 reproducible amplification DNA fragments, the majority of which were polymorphic. The values of genetic distance were calculated according to Nei & Li method (1979). The genetic distance among pairs of inbred lines ranged from 0.29 to 0.72. A dendrogram was constructed by an unweighted pair-group method using arithmetic averages (UPGMA). Cluster analysis divided the inbred lines into three groups: one including the flint lines only, and two groups composed of the dent type lines. The average value of genetic distance for pair comparison between the dent lines was higher (GD = 0.56) than that for the flint lines (GD = 0.46). Regression of hybrids grain yield on a genetic distance of their parental inbred lines showed very low correlation. The method used in this research is useful to allocate lines into a heterotic group rather than predict hybrid yield performance.

Źródło:

Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin; 2009, 253; 231-243
0373-7837
2657-8913

Pojawia się w:

Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 75.

Tytuł:

Ocena oznaczeń markera TATI – trzustkowego inhibitora trypsyny – u chorych na raka trzonu macicy z niekorzystnymi czynnikami rokowniczymi
Evaluation of TATI marker assays – the pancreatic trypsin inhibitor – in patients with endometrial cancer with unfavorable predictors

Autorzy:

Kozakiewicz, Barbara
Chądzyńska, Małgorzata
Dmoch-Gajzlerska, Ewa

Powiązania:

https://bibliotekanauki.pl/articles/1031452.pdf

Data publikacji:

2013

Wydawca:

Medical Communications

Tematy:

markery nowotworowe
markery raka trzonu macicy
tati
psti
negatywne czynniki rokownicze raka trzonu macicy
tumor markers
markers of endometrial cancer
negative predictors of endometrial cancer

Opis:

TATI marker (tumor-associated trypsin inhibitor) is most often assessed in patients with ovarian cancer. This paper presents the role and the usefulness of the marker in the evaluation of the treatment results in patients with endometrial cancer. The study was based on the evaluation of TATI marker level in 305 patients suffering from endometrial cancer treated at the Cancer Center between 1994 and1995 in Warsaw. In each patient the TATI marker level was measured from 3 to 7 times in the blood serum after each stage of the adjuvant treatment and in the initial part of the follow-up period. In order to assess the staging a postoperative protocol in force in 1988 (FIGO) was used and in accordance with this protocol, the patients were qualified for the adjuvant therapy, which consisted of the teletherapy, brachytherapy and hormonal therapy. All patients were observed on an outpatient basis after the treatment. The analysis of TATI marker levels in correlation with the features of cancer were carried out after a 17-year-long follow-up period. TATI marker levels have been evaluated in patients with unfavorable predictors identified in the operation protocol and in the histopathological protocol of the removed tumor. It was found that TATI level in the fourth sampling after the treatment was the most important value. TATI level increase in this assay was significantly correlated with the occurrence of local relapse or distant metastasis. The comparison of the results of patients with and without surgical removal of the lymph nodes has shown a significantly longer disease-free period in patients whose lymph nodes were not removed.
Marker TATI (tumor-associated trypsin inhibitor) najczęściej oceniany jest u chorych na raka jajnika. W pracy przedstawiono jego rolę i przydatność w ocenie wyników leczenia u chorych na raka trzonu macicy. Badanie przeprowadzono na podstawie oceny poziomu markera TATI wśród 305 chorych na raka trzonu macicy leczonych w Centrum Onkologii w latach 1994–1995 w Warszawie. U każdej chorej wykonano od 3 do 7 oznaczeń markera z surowicy krwi po każdym z etapów leczenia uzupełniającego i w początkowym okresie obserwacji po zakończeniu leczenia. W ocenie zaawansowania posługiwano się wówczas obowiązującym protokołem pooperacyjnym FIGO z 1988 roku i zgodnie z nim chore kwalifikowano do leczenia uzupełniającego, na które składały się teleterapia, brachyterapia lub hormonoterapia. Wszystkie chore po leczeniu były obserwowane ambulatoryjnie. Analizę poziomów markera TATI w korelacji z cechami raka przeprowadzono po 17-letnim okresie obserwacji. Oceniono poziomy markera TATI w grupie chorych z niekorzystnymi czynnikami rokowniczymi stwierdzonymi na podstawie protokołu operacyjnego i histopatologicznego usuniętego guza nowotworowego. Stwierdzono, że poziom TATI w czwartym pobraniu, po ukończeniu leczenia jest najistotniejszą wartością. Wzrost poziomu TATI w tym oznaczeniu znamiennie koreluje z wystąpieniem wznowy lub przerzutów odległych. Porównując wyniki leczenia operacyjnego bez usunięcia węzłów chłonnych i z ich usunięciem, stwierdzono znamiennie dłuższy czas wolny od choroby u chorych, u których nie były usuwane węzły chłonne.

Źródło:

Current Gynecologic Oncology; 2013, 11, 2; 103-114
2451-0750

Pojawia się w:

Current Gynecologic Oncology

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 76.

Tytuł:

Ocena oznaczeń markera TATI – trzustkowego inhibitora trypsyny – u chorych na raka trzonu macicy z niekorzystnymi czynnikami rokowniczymi
Evaluation of TATI marker assays – the pancreatic trypsin inhibitor – in patients with endometrial cancer with unfavorable predictors

Autorzy:

Kozakiewicz, Barbara
Chądzyńska, Małgorzata
Dmoch-Gajzlerska, Ewa

Powiązania:

https://bibliotekanauki.pl/articles/1031502.pdf

Data publikacji:

2013

Wydawca:

Medical Communications

Tematy:

markery nowotworowe
markery raka trzonu macicy
tati
psti
negatywne czynniki rokownicze raka trzonu macicy
tumor markers
markers of endometrial cancer
negative predictors of endometrial cancer

Opis:

TATI marker (tumor-associated trypsin inhibitor) is most often assessed in patients with ovarian cancer. This paper presents the role and the usefulness of the marker in the evaluation of the treatment results in patients with endometrial cancer. The study was based on the evaluation of TATI marker level in 305 patients suffering from endometrial cancer treated at the Cancer Center between 1994 and1995 in Warsaw. In each patient the TATI marker level was measured from 3 to 7 times in the blood serum after each stage of the adjuvant treatment and in the initial part of the follow-up period. In order to assess the staging a postoperative protocol in force in 1988 (FIGO) was used and in accordance with this protocol, the patients were qualified for the adjuvant therapy, which consisted of the teletherapy, brachytherapy and hormonal therapy. All patients were observed on an outpatient basis after the treatment. The analysis of TATI marker levels in correlation with the features of cancer were carried out after a 17-year-long follow-up period. TATI marker levels have been evaluated in patients with unfavorable predictors identified in the operation protocol and in the histopathological protocol of the removed tumor. It was found that TATI level in the fourth sampling after the treatment was the most important value. TATI level increase in this assay was significantly correlated with the occurrence of local relapse or distant metastasis. The comparison of the results of patients with and without surgical removal of the lymph nodes has shown a significantly longer disease-free period in patients whose lymph nodes were not removed.
Marker TATI (tumor-associated trypsin inhibitor) najczęściej oceniany jest u chorych na raka jajnika. W pracy przedstawiono jego rolę i przydatność w ocenie wyników leczenia u chorych na raka trzonu macicy. Badanie przeprowadzono na podstawie oceny poziomu markera TATI wśród 305 chorych na raka trzonu macicy leczonych w Centrum Onkologii w latach 1994–1995 w Warszawie. U każdej chorej wykonano od 3 do 7 oznaczeń markera z surowicy krwi po każdym z etapów leczenia uzupełniającego i w początkowym okresie obserwacji po zakończeniu leczenia. W ocenie zaawansowania posługiwano się wówczas obowiązującym protokołem pooperacyjnym FIGO z 1988 roku i zgodnie z nim chore kwalifikowano do leczenia uzupełniającego, na które składały się teleterapia, brachyterapia lub hormonoterapia. Wszystkie chore po leczeniu były obserwowane ambulatoryjnie. Analizę poziomów markera TATI w korelacji z cechami raka przeprowadzono po 17-letnim okresie obserwacji. Oceniono poziomy markera TATI w grupie chorych z niekorzystnymi czynnikami rokowniczymi stwierdzonymi na podstawie protokołu operacyjnego i histopatologicznego usuniętego guza nowotworowego. Stwierdzono, że poziom TATI w czwartym pobraniu, po ukończeniu leczenia jest najistotniejszą wartością. Wzrost poziomu TATI w tym oznaczeniu znamiennie koreluje z wystąpieniem wznowy lub przerzutów odległych. Porównując wyniki leczenia operacyjnego bez usunięcia węzłów chłonnych i z ich usunięciem, stwierdzono znamiennie dłuższy czas wolny od choroby u chorych, u których nie były usuwane węzły chłonne.

Źródło:

Current Gynecologic Oncology; 2013, 11, 2; 103-114
2451-0750

Pojawia się w:

Current Gynecologic Oncology

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 77.

Tytuł:

The relationship between alkaline phosphatase and bone alkaline phosphatase activity and the growth hormone/insulin-like growth factor-1 axis and vitamin D status in children with growth hormone deficiency

Autorzy:

Witkowska-Sędek, Ewelina
Stelmaszczyk-Emmel, Anna
Majcher, Anna
Demkow, Urszula
Pyrżak, Beata

Powiązania:

https://bibliotekanauki.pl/articles/1038401.pdf

Data publikacji:

2018

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

bone formation markers
vitamin D
recombinant human growth hormone treatment
children

Opis:

The relationships between bone turnover, the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and vitamin D are complex, but still not fully explained. The GH/IGF-1 axis and vitamin D can mutually modulate each other's metabolism and influence the activation of cell proliferation, maturation, and mineralization as well as bone resorption. The aim of this study was to evaluate the reciprocal associations between bone formation markers [alkaline phosphatase (ALP), bone alkaline phosphatase (BALP)], the GH/IGF-1 axis and 25-hydroxyvitamin D [25(OH)D] in children with growth hormone deficiency at baseline and during recombinant human growth hormone (rhGH) therapy. ALP, BALP, 25(OH)D and IGF-1 levels were evaluated in 53 patients included in this prospective three-year study. ALP, BALP and IGF-1 increased during rhGH therapy. Baseline ALP activity correlated positively with baseline height velocity (HV). ALP and BALP activity at 12 months correlated positively with HV in the first year of therapy. We found positive correlations between ALP and IGF-1 at baseline and during the first year of therapy, between BALP activity at 12 months and rhGH dose in the first year of therapy, and between doses of cholecalciferol in the first year of rhGH therapy and early changes in BALP activity during rhGH therapy. Our results indicate that vitamin D supplementation enhances the effect of rhGH on bone formation process, which could improve the effects of rhGH therapy. ALP and BALP activity are useful in the early prediction of the effects of rhGH therapy, but their utility as long-term predictors seemed insufficient.

Źródło:

Acta Biochimica Polonica; 2018, 65, 2; 269-275
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 78.

Tytuł:

Molecular Fingerprints of Thyroid Cancer Cells by Using Library of Molecular Receptors Formed by N-Lipidated Peptides Immobilized on Cellulose

Autorzy:

Fraczyk, Justyna
Walczak, Małgorzata
Balcerzak, Waldemar
Pokajewicz, Katarzyna
Wieczorek, Piotr
Młynarski, Wojciech
Fendler, Wojciech
Kaminski, Zbigniew J.

Powiązania:

https://bibliotekanauki.pl/articles/895507.pdf

Data publikacji:

2018-08-31

Wydawca:

Polskie Towarzystwo Farmaceutyczne

Tematy:

surface modification
cancer markers
chemical receptor
molecular mono-layer
immobilized peptides

Opis:

A novel diagnostic method based on recognition of qualitative and quantitative composition of healthy and tumor tissue samples by library of molecular receptors was presented. Molecular receptors were formed by self-organization of N-lipidated peptides attached in the regular fashion via aminophenylamino-1,3,5-triazine linker to the surface of cellulose plate. For samples testing, the library was cloned into multiple, identical copies and for each experiment the new clone was used. The binding process was monitored by staining the discs with Brilliant Black and quantitative color measurement was performed in 256 grade gray scale. Substantial differences in the composition of healthy and tumor samples were observed in most cases. The highly individual chemical fingerprints were found to be reliant on the cancer type. For malignant papillary thyroid cancer statistical analysis identified two receptors most useful for diagnostic purposes.

Źródło:

Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 4; 1017-1029
0001-6837
2353-5288

Pojawia się w:

Acta Poloniae Pharmaceutica - Drug Research

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 79.

Tytuł:

Genetic diversity of Italian populations of Abies alba

Autorzy:

Belletti, Piero
Ferrazzini, Diana
Ducci, Fulvio
De Rogatis, Anna
Mucciarelli, Marco

Powiązania:

https://bibliotekanauki.pl/articles/956994.pdf

Data publikacji:

2017

Wydawca:

Polska Akademia Nauk. Instytut Dendrologii PAN

Tematy:

silver fir
genetic differentiation
glacial refugia
regions of provenance
ssr markers

Opis:

Silver fir (Abies alba) is a common tree species in the mountainous areas in Europe. A number of natural stands in the hilly regions of northern Europe represent relic populations. The aim of the research was to evaluate the diversity present in Italian populations of the species. Genetic diversity was assessed in 45 silver fir populations covering the species’ distribution range in Italy, based on the allelic variation present at seven microsatellite loci (SSRs). A consistent level of intra-population variability was present. Several of the populations displayed signs of ongoing genetic erosion, and evidence for a recent bottleneck in some was identified. Populations from the eastern Alps and the Apennines were more variable than those sampled from the western Alps. About 8% of the overall genetic variance was found between populations, with the remainder representing variation present within the populations. The data suggested that the southern Apennines acted as a refugium during the most recent Ice Age, and that many of the populations from this area have remained isolated over a prolonged period. Smaller and more isolated populations have experienced genetic drift, whereas the larger ones have preserved a high level of diversity. Identification of genetically homogeneous regions could be informative for the management of genetic resources.

Źródło:

Dendrobiology; 2017, 77; 147-159
1641-1307

Pojawia się w:

Dendrobiology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 80.

Tytuł:

Formulaic Sequences and Meta-Discourse Markers in Applied Linguistics Research Papers. A cross-linguistic corpus-based analysis of native and non- native authors’ published articles

Autorzy:

Assassi, Tarek
Merghmi, Kenza

Powiązania:

https://bibliotekanauki.pl/articles/2158862.pdf

Data publikacji:

2023-01-05

Wydawca:

Academicus. International Scientific Journal publishing house

Tematy:

metadiscourse markers
formulaic language
academic writing
cross-linguistic
Hyland’s classification

Opis:

Metadiscourse markers and their importance to academic writing are essential research subjects nowadays. The current corpus-based study aims at identifying interactional and interactive metadiscourse markers in terms of frequency and function in the abstract section of published research articles in applied linguistics developed by Algerian, Saudi, and Native researchers. 20 research articles for each group, with a total of 60 articles have been randomly selected and compiled as the research corpus for this study, then analyzed qualitatively and quantitatively using AntConc.3.2.4 relying on Hyland’s classification of metadiscourse markers. As a comparative study, the research considered the abstracts written by natives as a benchmark and attempted to find an answer to the main inquiry related to the frequency of use of metadiscourse devices by Algerian and Saudi researchers in comparison to their Native counterparts. The main research results showed how close were Algerian abstracts to native ones in terms of using endophorics, frame markers, code glosses, hedges, attitude markers, and self-mentions. While Saudi abstracts were close to the benchmark only in two markers that are transitions and engagement markers. The rest of the devices were shown to be far from the native norm in both cases. The findings also revealed that the use of metadiscourse markers is not the only indicator of papers’ publication rate in indexed journals by comparing the corpus analysis results to the source of the articles (journals), to find that even if Algerian researchers publish less in high indexed journals in comparison to Saudis, they are still closer in using markers to the natives as a benchmark.

Źródło:

Academicus International Scientific Journal; 2023, 14, 27; 154-175
2079-3715
2309-1088

Pojawia się w:

Academicus International Scientific Journal

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 81.

Tytuł:

Markery funkcjonalne dla cech ilościowych
Functional markers for quantitative traits

Autorzy:

Surma, Maria
Adamski, Tadeusz
Krystkowiak, Karolina
Kuczyńska, Anetta
Mikołajczak, Krzysztof
Ogrodowicz, Piotr

Powiązania:

https://bibliotekanauki.pl/articles/2198254.pdf

Data publikacji:

2012-06-28

Wydawca:

Instytut Hodowli i Aklimatyzacji Roślin

Tematy:

geny kandydujące
markery molekularne
polimorfizm
QTL
candidate genes
functional markers
polymorphism

Opis:

Badania dotyczące molekularnych podstaw zmienności cech ilościowych są obecnie szeroko podejmowane, zarówno dla roślin, jak i zwierząt czy człowieka. Celem tych badań jest m.in. rozwój systemów markerów funkcjonalnych DNA (FM). Do opracowania markerów FM niezbędne jest więc funkcjonalne scharakteryzowanie wybranych genów i znajomość sekwencji ich alleli, identyfikacja polimorficznych motywów funkcjonalnych w obrębie tych genów i potwierdzenie związku między polimorfizmem sekwencji DNA a zmiennością cechy ilościowej. W pracy przedstawiono przykłady genów kandydujących do opracowania markerów funkcjonalnych: geny półkarłowatości Dwarf8 u kukurydzy i denso u jęczmienia oraz geny Glu1 kodujące wysokocząsteczkowe podjednostki białek gluteninowych u pszenicy. Przedyskutowano przewagę markerów funkcjonalnych nad markerami sprzężonymi z loci dla cech ilościowych.
Molecular bases of quantitative trait variation in plant, animal and human populations are currently extensively studied. The aim of those studies is, among others, development of functional markers (FM). Development of FM requires allele sequences of functionally characterized genes, identification of polymorphic, functional motifs within genes and confirmation of association between DNA sequence polymorphism and variation of quantitative traits. In the paper examples of candidate genes for FM development are presented: semidwarf genes Dwarf8 in maize and denso in barley, and genes Glu1 encoding high molecular weight subunits of glutenin in wheat. The advantage of functional markers over markers linked to quantitative trait loci is discussed.

Źródło:

Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin; 2012, 264; 5-14
0373-7837
2657-8913

Pojawia się w:

Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 82.

Tytuł:

β-Glucan-Mediated Alleviation of NaCl Stress in Ocimum basilicum L. in Relation to the Response of Antioxidant Enzymes and Assessment DNA Marker

Autorzy:

Alhasnawi, Arshad Naji

Powiązania:

https://bibliotekanauki.pl/articles/124951.pdf

Data publikacji:

2019

Wydawca:

Polskie Towarzystwo Inżynierii Ekologicznej

Tematy:

NaCl-stress
beta-glucan
antioxidants
molecular markers
DNA variations
genetic stability

Opis:

Salinity is one of the most important abiotic stresses which can negatively affect the plant metabolic processes in the world. This can impact the plant production, either for economic or sustenance benefits. The salinity stress can cause many physiological and biochemical changes in the plants. β-glucans are important polysaccharides, which are present in the cell walls of various cereal grains. They protect the plant responses and occur in plant suspensions. In this study, the researchers attempted to investigate various physiological mechanisms and determine the role of the β-glucans in the NaCl-mediated stress conditions on the Ocimum basilicum L. seedlings. For this purpose, they carried out an experiment for assessing various shoot and root parameters along with the antioxidant enzyme activities, proline levels and the ISSR markers. When the seedlings were exposed to the NaCl stress conditions, they showed a significant decrease in the growth parameters and an increase in the antioxidant and proline levels compared to the control seedlings grown under normal saline conditions. On the other hand, the β-glucantreated seeds, when grown under the saline stress conditions, showed better growth parameters as well as high antioxidant enzyme activities and proline levels, compared to the control and NaCl-treated plants. Furthermore, a PCR analysis was carried out using the ISSR-marker technology, which could help in evaluating the DNA fingerprints and genetic variations in the plants. The results indicated that the exogenous application of the β-glucans could protect the antioxidant enzyme activities and protect the plants against the salinity stresses, without affecting the DNA-markers without affecting the genetic variations and could be a better choice for use in DNA-markers.

Źródło:

Journal of Ecological Engineering; 2019, 20, 8; 90-99
2299-8993

Pojawia się w:

Journal of Ecological Engineering

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 83.

Tytuł:

PSA ciągle najlepszy marker nowotworowy, modyfikacje testu i nowe markery raka stercza
PSA still the best cancer marker, PSA test modifications and new prostate cancer markers

Autorzy:

Braczkowski, Michał
Białożyt, Michał
Braczkowski, Ryszard
Kondera-Anasz, Zdzisława

Powiązania:

https://bibliotekanauki.pl/articles/1034707.pdf

Data publikacji:

2011

Wydawca:

Śląski Uniwersytet Medyczny w Katowicach

Tematy:

markery nowotworowe
rak stercza
łagodny przerost stercza
psa
nowe
markery raka stercza
biologia molekularna
cancer markers
prostate cancer
benign prostatic hyperplasia
new prostate cancer markers
molecular biology

Opis:

The prostate-specific antigen is considered to be the most eff ective, though far from ideal, tumor marker. The basic aim of its application is to diagnose and diff erentiate between cancer and benign prostatic hyperplasia. The value of markers in case of prostate cancer is of particular importance, because of the long-term asymptomatic development. And recently, these values have become even more signifi cant, since there has been an increasing tendency to suff er from the disease. Our study presents advantages and imperfections of the PSA test, its modifi cations (e.g. dynamic tests) introduced in order to increase the specificity and sensitivity of the test, and thus its reliability. Subsequently proenzymes and PSA precursor forms as well as the opportunities for their use in the diagnostics are described. The rest of the article is devoted to the description of new potential prostate cancer markers, the implementation of which is closely associated with the development of molecular biology techniques. Among them the most important are: new kallikreins (PSA is also the member of kallikreins family), EPCA-2, PCA3, AMACR, products of gene fusion and rearrangements, GSTP1 hypermethlation, free non-cellular DNA and some antibodies.
Od wielu lat specyficzny antygen sterczowy (PSA) uważany jest za najlepszy, choć daleki od ideału marker nowotworowy. Podstawowy cel jego zastosowania to pomoc w rozpoznawaniu i różnicowaniu raka i łagodnego przerostu gruczołu krokowego. Wartość markerów nowotworowych w przypadku raka stercza jest szczególnie ważna wobec faktu wieloletniego bezobjawowego rozwoju tego nowotworu, a szczególnego znaczenia nabiera ona w ostatnich latach, gdy obserwujemy stale wzrastającą tendencję do zachorowań. W pracy przedstawiono zalety i wady testu PSA, jego modyfikacje (np. testy dynamiczne) wprowadzone w celu zwiększenia czułości i specyficzności oraz – co za tym idzie – wiarygodności testu. W dalszej kolejności opisano proenzymy oraz formy prekursorowe PSA i możliwości wykorzystania ich w diagnostyce. W drugiej części pracy opisano nowe, potencjalne markery raka stercza, których próby wprowadzenia wiążą się z rozwojem technik biologii molekularnej. Należy tu wymienić kolejne kalikreiny (PSA jest także przedstawicielem tej rodziny), EPCA-2, PCA3, AMACR, produkty rearanżacji i fuzji genów, hipermetylacja GSTP1, wolne DNA w surowicy krwi, przeciwciała i szereg innych o nieco mniejszym znaczeniu.

Źródło:

Annales Academiae Medicae Silesiensis; 2011, 65, 1-2; 89-98
1734-025X

Pojawia się w:

Annales Academiae Medicae Silesiensis

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 84.

Tytuł:

Compositional analysis of interrogative imperatives in Hungarian

Autorzy:

Kleiber, Judit
Alberti, Gábor

Powiązania:

https://bibliotekanauki.pl/articles/1040232.pdf

Data publikacji:

2017-12-30

Wydawca:

Katolicki Uniwersytet Lubelski Jana Pawła II

Tematy:

pragmatico-semantic analysis
belief–desire–intention framework
discourse representation theory
discourse markers

Opis:

The paper investigates utterances which combine imperative and interrogative elements in Hungarian. We intend to explore the scope of the hypothesis that the pragmatico-semantic content of mixed-type sentences can be obtained compositionally. We present four types of interrogative imperative. The imperative factor is indicated by subjunctive morphology on the verb. The interrogative character is represented by (1) rise-fall intonation which marks polar questions, (2) the discourse marker ugye expressing bias, (3) the particle vajon expressing self-reflection or hesitation, and (4) wavy intonation which indicates surprise. We claim that such sentences are primarily questions with their main function being ‘request for instruction’. For the analysis, we take a formal pragmatico-semantic point of view. Our goal is to demonstrate how these sentences can be analyzed compositionally within a belief–desire–intention frame. We apply the formal dynamic discourse- and mind-representation theory ReALIS. We have found that the pragmatico-semantic content (intensional profile) of each type can be constructed via using two formal operations: concatenation and pragmasemantic blending. The composition produces the required output, namely that the interrogation / bias / speculation / surprise which pertains to an eventuality in the case of a simple question, pertains to the “commanding” of this eventuality in the case of interrogative imperatives.

Źródło:

Linguistics Beyond and Within; 2017, 3; 117-135
2450-5188

Pojawia się w:

Linguistics Beyond and Within

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 85.

Tytuł:

The Order of Emergence of the Morphological Markers of Temporal Expression in the Croatian EFL Learners’ Longitudinal Speech Production Data

Autorzy:

Semren, Mirjana

Powiązania:

https://bibliotekanauki.pl/articles/555461.pdf

Data publikacji:

2018

Wydawca:

Uniwersytet Warszawski. Wydział Lingwistyki Stosowanej

Tematy:

morphological markers
order of emergence
grammatical morphemes
verb tenses
obligatory occasion analysis

Opis:

This study addresses the acquisition of the morphological markers of temporal expression in the interlanguage of Croatian primary school learners of English as a foreign language (EFL). The acquisition of morphological markers was documented regarding the order of emergence of nine grammatical morphemes. The emergence of these morphemes was examined following the obligatory occasion analysis (R. Brown 1973) which identified the obligatory contexts for each morpheme and the number of their correct suppliance. The order of emergence was obtained by the group score method (H.C. Dulay/ M.K. Burt 1974) according to which the morphemes were ranked in decreasing order of accuracy. Additionally, the study documented the order of emergence of four verb tenses. The data collection period comprised three generations of Grade 8 learners thus yielding a total of 56 transcribed recordings. The learners’ language samples were gathered via task-based activities. Although the findings displayed discrepancies in the ranking orders obtained for different generations of Grade 8 learners, the Spearman rank order correlations suggest that there seems to be a homogeneous order of emergence across three generations of the eighth graders. The results revealed not only that Present Continuous emerged after Simple Present but also showed that Present Perfect emerged after Simple Past.

Źródło:

Applied Linguistics Papers; 2018, 25/2; 89-106
2544-9354

Pojawia się w:

Applied Linguistics Papers

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 86.

Tytuł:

Някои особени лексеми в старобългарския превод на Иполитовото тълкувание на Книга на пророк Даниил

Autorzy:

Илиев [Iliev], Иван [Ivan] И. [I.]

Powiązania:

https://bibliotekanauki.pl/articles/677380.pdf

Data publikacji:

2016

Wydawca:

Polska Akademia Nauk. Instytut Slawistyki PAN

Tematy:

Book of Daniel
Hippolytus of Rome
commentary
Old Bulgarian translation
lexical markers

Opis:

Some specific lexemes in the Old Bulgarian translation of Hippolytus of Rome’s Commentaries on the Book of Prophet DanielThe object of the current research is Talkovanie na Kniga na propok Daniil – the Slavonic version of the Commentaries on the Book of Prophet Daniel (Commentarii in Danielem, CPG 1873) by Hippolytus of Rome (c. 170–235), the earliest and most profound commentaries on this Old Testament book. They were written round 204 and their translation into Old Bulgarian can be counted among the earliest works of Bulgarian literature. The time of the Commentaries’ translation is under discussion, its dating ranging from the last decades of the ninth to the middle of the tenth century. Some linguistic facts of the Commentaries have sporadically been compared with the partial translation of the Book of the Prophet Daniel, included in the Prophetologion. Also, some comparisons have been made between the Slavonic translation of the Commentaries and the so-called Talkovni proroci – a translation of Old Testament books of prophets with commentaries. The analysis is based on a 1519 manuscript of the Commentaries (No. 486 from the Volokolamsk Collection, Russian State Library, Moscow), which follows the tradition of the earlier copies and most profoundly keeps the content of the Commentaries. In addition to morphological particularities, in the text there are many lexical idiosyncrasies, which can facilitate the dating and localization of the translation. Among these lexical markers can be singled out which show more interesting data. Many lexemes can be found which are particular to the early written codices and testify to the antiquity of the translation. For instance, some specific lexemes match with words, used in the Codex Suprasliensis and the First Miscellany of Tsar Simeon (Izbornik of 1073), which shows that the Commentaries are one of the earliest translated works of the Old Bulgarian literature. Wybrane charakterystyczne leksemy w starobułgarskim przekładzie Komentarzy do Księgi Proroka Daniela Hipolita RzymskiegoPrzedmiotem artykułu jest słowiańska wersja Komentarzy do Księgi Proroka Daniela (Commentarii in Danielem, CPG 1873) autorstwa Hipolita Rzymskiego (ok. 170–235), najwcześniejszych i najbardziej wnikliwych komentarzy do tej starotestamentowej księgi. Zostały one napisane około 204 roku, a ich przekład na język starobułgarski sytuuje się wśród najstarszych dzieł literatury bułgarskiej. Wciąż dyskutowany jest czas jego powstania: od ostatnich dekad wieku IX do połowy X. Niektóre fakty językowe związane z Komentarzami były sporadycznie porównywane z częściowym przekładem Księgi Proroka Daniela, zawartym w paremejniku. Porównywano także słowiański przekład Komentarzy z tak zwaną Księgą Proroków Starego Testamentu wraz z komentarzami. Artykuł koncentruje się na rękopisie z 1519 roku (Nr 486 w Zbiorze z Biblioteki Wołokołamska, Rosyjska Biblioteka Państwowa, Moskwa), który śledzi tradycję wcześniejszych kopii i najdokładniej zachowuje zawartość Komentarzy. Oprócz ich morfologicznej specyfiki w tekście znajduje się wiele cech leksykalnych, które pomagają określić datę i miejsce powstania przekładu. Wśród nich znajdują się markery leksykalne, które zasługują na uwagę, gdyż prowadzą do ciekawych odkryć. Wiele leksemów zawartych w tekście odnosi się do wczesnych kodeksów i świadczy o starożytności przekładu. Niektóre charakterystyczne leksemy łączą się ze słowami użytymi w Codex Suprasliensis i Pierwszym Zborniku Cara Symeona (Izbornik, 1073 rok), co dowodzi, że Komentarze są jedną z najwcześniejszych przetłumaczonych prac w obrębie literatury starobułgarskiej.

Źródło:

Slavia Meridionalis; 2016, 16
1233-6173
2392-2400

Pojawia się w:

Slavia Meridionalis

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

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Skocz do pozycji: 87.

Tytuł:

Investigating L2 spoken English through the role play learner corpus

Autorzy:

Nava, Andrea
Pedrazzini, Luciana

Powiązania:

https://bibliotekanauki.pl/articles/780522.pdf

Data publikacji:

2011-04

Wydawca:

Uniwersytet im. Adama Mickiewicza w Poznaniu

Tematy:

learner corpus research
second language spoken discourse
spoken grammar
tails
discourse markers

Opis:

We describe an exploratory study carried out within the University of Milan, Department of English the aim of which was to analyse features of the spoken English of first-year Modern Languages undergraduates. We compiled a learner corpus, the “Role Play” corpus, which consisted of 69 role-play interactions in English carried out by first-year students at B1+-B2 levels according to the Common European Framework of Reference. The analysis focused on the students’ use of two features of spoken English grammar, tails and the discourse markers ‘yes’ and ‘yeah’. Instances of these features from the data were compared with examples of British native speaker, learner and Italian native speaker usage. Preliminary findings pointed to the role of the students’ first language, L2 proficiency and specific task features in the range and frequency of these phenomena as well as in the functions they deployed in the spoken discourse of the informants.

Źródło:

Studies in Second Language Learning and Teaching; 2011, 1, 1; 37-56
2083-5205
2084-1965

Pojawia się w:

Studies in Second Language Learning and Teaching

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 88.

Tytuł:

Poziom katecholamin w ślinie podczas stresu egzaminacyjnego i wysiłku poznawczego
Salivary catecholamines in examinational stress and cognitive effort

Autorzy:

Rudnicki, Konrad
Rutkowska, Aleksandra
Wieczorek, Marek

Powiązania:

https://bibliotekanauki.pl/articles/2013965.pdf

Data publikacji:

2015

Wydawca:

Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego

Tematy:

katecholaminy
dopamina
noradrenalina
adrenalina
biomarkery
catecholamines
examinational stress
cognitive effort
salivary markers

Opis:

By ustalić przydatność katecholamin w ślinie do badania stresu, pobrano próbki od 30 studentów przed egzaminem oraz w dniu pozbawionym stresorów. Następnie aby zbadać wpływ wysiłku poznawczego na poziomy katecholamin, przebadano 31 ochotników, którzy uczestniczyli w dwóch spotkaniach poświęconych realizacji różnych testów poznawczych. Za pomocą HPLC-ED zmierzono poziomy noradrenaliny, dopaminy i adrenaliny w ślinie. W grupie przed egzaminem zaobserwowano wyłącznie obniżony poziom dopaminy w porównaniu do dnia nieobciążonego stresorami. W drugiej grupie wysiłek poznawczy wywołał podwyższenie poziomów wszystkich trzech katecholamin. Zważywszy na niejednoznaczne wyniki z dotychczasowych badań wydaje się, iż adrenalina i noradrenalina w ślinie mogą być stosowane jako markery aktywności współczulnej w badaniach psychologicznych.
In order to determine utility of salivary catecholamines in stress studies, samples were collected from 30 students before an exam and on an ordinary day. Subsequently, to examine the effect of cognitive effort on catecholamines, 31 volunteers, on two days, performed two sets of different cognitive tasks. Noradrenaline, adrenaline and dopamine levels were examined with HPLC-ED. Stressed group shown alleviated levels of dopamine, while levels of other substances remained unchanged. In the second group cognitive effort elicited elevated excretion of all three catecholamines. Given conflicting results from previous literature it appears that salivary adrenaline and noradrenaline might be useful as non-invasive markers of sympathetic activity in psychological research.

Źródło:

Acta Universitatis Lodziensis. Folia Psychologica; 2015, 19; 89-107
2353-4842

Pojawia się w:

Acta Universitatis Lodziensis. Folia Psychologica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 89.

Tytuł:

"Ponad" – "około" – "gdzieś" – "dobry", czyli o aproksymatorach na różnych piętrach nieprzedmiotowego poziomu języka
"Ponad" – "około" – "gdzieś" – "dobry" (‘over’ – ‘about’ – ‘somewhere’ – ‘good’), or about the approximators on different floors of the non-objective level of language

Autorzy:

Doboszyńska-Markiewicz, Katarzyna

Powiązania:

https://bibliotekanauki.pl/articles/29431832.pdf

Data publikacji:

2023

Wydawca:

Uniwersytet Mikołaja Kopernika w Toruniu. Wydawnictwo UMK

Tematy:

aproksymatory
operatory adnumeratywne
metatekst
discourse markers
gramatykalizacja
approximators
adnumerative operators
metatext
grammaticalization

Opis:

Artykuł ukazuje polskie aproksymatory o różnych właściwościach formalnych jako ilustrację teorii klasyfikacji wyrażeń metatekstowych Jadwigi Wajszczuk. Są to dawne przyimki, zaimki i przymiotniki jakościowe, które przeszły z przedmiotowego na nieprzedmiotowy poziom języka (proces gramatykalizacji), zmieniając swoje cechy gramatyczne i znaczeniowe. Chociaż w klasyfikacji Wajszczuk aproksymatory zaliczone zostały do operatorów metapredykatywnych, część z nich wykazuje cechy metaoperatorów, a inne plasują się na pograniczu metatekstu i słownictwa przedmiotowego.
The article presents Polish approximators with different formal properties as an illustration of Jadwiga Wajszczuk’s theory of metatextual expression classification. These are former prepositions, pronouns, and qualitative adjectives, which have passed from the object to the non-object level of language (the process of grammaticalization), changing their grammatical and semantic features. Although in Wajszczuk’s classification approximators are classified as metapredicative operators, some of them show features of meta-operators, whereas others are classified somewhere between metatext and object vocabulary.

Źródło:

Linguistica Copernicana; 2023, 19; 71-87
2080-1068
2391-7768

Pojawia się w:

Linguistica Copernicana

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 90.

Tytuł:

Leukemic stem cells: from metabolic pathways and signaling to a new concept of drug resistance targeting

Autorzy:

Styczynski, Jan
Drewa, Tomasz

Powiązania:

https://bibliotekanauki.pl/articles/1040856.pdf

Data publikacji:

2007

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

stem cell markers
metabolic pathways
drug resistance
leukemic stem cells
cancer stem cells

Opis:

Cancer stem cells are a small subset of cancer cells constituting a reservoir of self-sustaining cells with the exclusive ability to self-renew and maintain the tumor. These cells are identified by specific stem cell markers: antigens, molecules and signaling pathways. Transcription factors and molecules associated with oncogenesis, such as NF-κB, Bmi-1, Notch, WNT beta-catenin, Sonic hedgehog and their biochemical pathways, active only in a small minority of cancer cells might play key roles in determining the biology and the overall long-term behavior of a tumor. The molecules and pathways specific for cancer stem cells, which contribute to their drug resistance, are potential targets for new therapeutic strategies.

Źródło:

Acta Biochimica Polonica; 2007, 54, 4; 717-726
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 91.

Tytuł:

Application of nine species-specific microsatellite loci to characterize three pike-perch (Sander lucioperca) populations from the Aral Sea basin in Uzbekistan

Autorzy:

Khurshut, E.
Kohlmann, K.

Powiązania:

https://bibliotekanauki.pl/articles/363116.pdf

Data publikacji:

2009

Wydawca:

Uniwersytet Warmińsko-Mazurski w Olsztynie

Tematy:

sandacz
markery mikrosatelitarne
heterozygotyczność
zróżnicowanie genetyczne
pike-perch
microsatellite markers
heterozygosities
genetic differentiation

Opis:

The pike-perch is one of the main commercial fish species in Uzbekistan. Historically, it inhabited the Aral Sea and deltas of inflowing rivers (Amu-Darya and Syr-Darya). At the beginning of the 1960s it was introduced into water bodies of the middle Amu-Darya and Syr-Darya from the Ural River. The present study was aimed to evaluate the current genetic status of wild pike-perch populations from different water bodies using nine recently isolated species-specific microsatellite markers. The three examined Uzbek pike-perch populations expressed significantly higher average numbers of alleles per locus (5.56 to 14.22) than three year-classes of a German wild population (3.11 to 3.78) included for comparison. On the other hand, average observed and expected heterozygosities were not significantly different in both regions (0.743 and 0.760 in Uzbek pike-perch; 0.576 and 0.471 in German pike-perch). After sequential Bonferroni corrections all Uzbek populations were found to be in Hardy-Weinberg equilibrium. Genetic differentiation between all populations as estimated by FST values was statistically significant. Pike-perch from Amu-Darya River delta and Tudakul reservoir were less differentiated from each other probably due to gene flow between them (both water bodies are connected) whereas the more distinct Syr-Darya River population showed indication for introgression with non-native individuals stocked in that region. Since stocking is widely practiced to satisfy the growing demand of pike-perch fisheries in Uzbekistan, fish seed for such activities should be obtained from local, genetically undisturbed populations such as the Amu-Darya River delta population.

Źródło:

Environmental Biotechnology; 2009, 5, 1; 3-10
1734-4964

Pojawia się w:

Environmental Biotechnology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 92.

Tytuł:

Związek białek zapasowych z zimotrwałością u wybranych mieszańców pszenicy ozimej
Relationship between wheat storage proteins and winter hardiness in chosen hybrids of winter wheat

Autorzy:

Witkowska, Krystyna
Witkowski, Edward
Śmiałowski, Tadeusz
Waga, Jacek

Powiązania:

https://bibliotekanauki.pl/articles/2198492.pdf

Data publikacji:

2013-06-30

Wydawca:

Instytut Hodowli i Aklimatyzacji Roślin

Tematy:

elektroforeza
markery biochemiczne
pszenica ozima
zimotrwałość
electrophoresis
bichemical markers
winter wheat
winter hardiness

Opis:

Celem badań było poszukiwanie związków pomiędzy markerami biochemicznymi a stopniem przezimowania u 2 grup pszenic ozimych: 19 wieloliniowych genotypów (90 linii F5) pochodzących z 6 kombinacji mieszańcowych pszenicy zwyczajnej (T. aestivum ssp. vulgare) oraz trzech par genotypów wytworzonych z mieszańca orkiszu (odmiany Oberkummer Rotkorn (Triticum aestivum spelta L.) i rodu LAD 480 (T. aestivum ssp. vulgare). Materiał poddano analizom elektro¬foretycznym. W pierwszej grupie badanego materiału stwierdzono silne zróżnicowanie pod względem zimotrwałości wahające się od 4 do 9 stopni (w skali 9°). Uzyskane wyniki sugerują, że kombinacja podjednostek HMW glutenin [Glu A1(Null), Glu B1(7+9), Glu D1 (5+10)] jest powiązana z podwyższoną zimotrwałością pszenicy ozimej. Zimotrwałość drugiej grupy mieszańców oddalonych była niższa i wahała się od 1 do 5 stopnia. Markerami wysokiej zimotrwałości u tej grupy mieszańców okazał się blok białek gluteninowych z podjednostką HMW warunkowanych przez locus Glu A1 z podjednostką „2”i locus Glu D1 z podjednostką „5+10/2+12” oraz blok białek gliadynowych z podjednostkami zawierającymi markery białkowe linii z null allelem w locus Gli B2.
The aim of these studies was to find out whether polymorphic wheat storage proteins (gliadins and HMW glutenins) and winter hardiness are interrelated. Two sets of winter wheats were analyzed. In the first set 19 groups of hybrid genotypes (90 lines in total) of F5 generation from cross combinations between common wheat (Triticum aestivum ssp. vulgare) cultivars and strains were analyzed. The second set comprised four pairs of hybrid genotypes originating from crossing between spelt (Triticum aestivum ssp. spelta, cv. Obercummer Rotkorn) and common wheat breeding strain LAD 480. Gliadins and HMW glutenins extracted from individual kernels of analyzed hybrid genotypes were separated using electrophoretic techniques: A-PAGE and SDS-PAGE. The obtained results suggested close relationships between HMW glutenin subunits: Glu A1-1, Glu B1-7+9/6+8, Glu D1-5+10 and gliadin null alleles localized on the chromosome 6B (locus Gli B2) and winter hardiness of winter wheat.

Źródło:

Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin; 2013, 268; 23-34
0373-7837
2657-8913

Pojawia się w:

Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 93.

Tytuł:

Location of markers of aluminium tolerance genes on rye chromosomes (Secale cereale L.)

Autorzy:

Wiśniewska, Iwona
Rafalski, Andrzej

Powiązania:

https://bibliotekanauki.pl/articles/2199029.pdf

Data publikacji:

2006-06-22

Wydawca:

Instytut Hodowli i Aklimatyzacji Roślin

Tematy:

aluminium tolerance
chromosomal location
DNA-DNA hybridisation
PCR markers
wheat/rye addition lines

Opis:

The aim of presented work was to identify of PCR amplifiedDNAfragments differentiating aluminium tolerant and sensitive forms of rye and to locate the markers on rye chromosomes. For identification of markers, the PCR system with semi-specific primers targeting intron-exon sequences of plant genes was applied. The modified method of bulked segregant analysis was used. The pooled DNAs of two or three F2 segregating populations were screened together with DNA of their parental inbred lines. Potential marker of tolerance gene was located on rye chromosomes using wheat/rye (Chinese Spring/Blanco) additional lines. The specific probes obtained from DNA fragments differentiating sensitive and tolerant forms of rye were hybridized to PCR amplified DNA fragments of sensitive and tolerant forms of rye and the set of wheat/rye addition lines. Independently of the method of digoxygenin labelling (primer extension or Taq polymerase reaction), the probes obtained showed similar hybridization patterns. The results of hybridisation of 21 probes prepared from 12 DNA fragments confirmed connection of selected DNA fragments with to aluminium tolerance or sensitivity. Most of these DNA fragments originated from tolerant forms of rye. Using this method it was possible to locate eight DNA fragments on rye chromosomes. Three DNA fragments hybridised to chromosome 4R, two DNA fragments to chromosome 6R and single DNA fragments to chromosomes 1R, 2R and 3R. Four DNA fragments indicating clear relationship with character studied were not located on particular chromosomes using this set of wheat/rye addition lines. Hybridisation of probes prepared from four DNA fragments revealed length polymorphism. Probes prepared from two DNA fragments were characterised as dominant markers. In other cases the type of marker (dominant/codominat) was not fully documented.

Źródło:

Plant Breeding and Seed Science; 2006, 53; 43-52
1429-3862
2083-599X

Pojawia się w:

Plant Breeding and Seed Science

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 94.

Tytuł:

Analiza Sytemu Termoanemometru Falowego
Analysis of a Hot-Wire Anemometer System

Autorzy:

Biernacki, Z.

Powiązania:

https://bibliotekanauki.pl/articles/209121.pdf

Data publikacji:

2008

Wydawca:

Wojskowa Akademia Techniczna im. Jarosława Dąbrowskiego

Tematy:

termoanemometr falowy
znaczniki termiczne
medium przepływowe
hot-wire anemometer
thermal markers
flowing medium

Opis:

W pracy przedstawiono badania Systemu Termoanemometru Falowego (STF), opracowanego i zbudowanego na podstawie koncepcji autora. Pierwotna idea znaczników cieplnych, podana przez Kovaszyna, posłużyła do opracowania STF przeznaczonego do określania prędkości przepływu medium poprzez pomiar czasu przelotu tych znaczników, unoszonych przez badane medium przepływowe (np. gaz), na dokładnie ustalonym a priori odcinku, będącym charakterystycznym parametrem konstrukcyjnym sensora pomiarowego. Zakres badań obejmuje analizę modelu z wykorzystaniem symulacji komputerowych, jak również badania laboratoryjne. Praca koncentruje się głównie na użyciu adekwatnych metod matematycznych do analizy modelu.
The paper deals with investigation of a Hot-Wire Anemometer System developed and built on the basis of the author's own design idea. The Hot-Wire Anemometer System (STE) is based on Kovasznay's idea of measuring the transit time of thermal markers drifted by the flowing medium (e.g. gas) on the a priori known interval, which is a design constant of the measuring converter. The scope of invastigation includes model studies employing computer simulation techniques as well as experiments on a laboratory stand. The work is focused mainly on the model studies with the use of adequate mathematical methods.

Źródło:

Biuletyn Wojskowej Akademii Technicznej; 2008, 57, 2; 73-89
1234-5865

Pojawia się w:

Biuletyn Wojskowej Akademii Technicznej

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 95.

Tytuł:

Badanie samoniezgodności oraz podobieństwa genetycznego zróżnicowanych genotypowo form lucerny (Medicago sativa L.)
The study of self-incompatibility and genetic similarity of genetically differentiated forms of alfalfa (Medicago sativa L.)

Autorzy:

Broda, Zbigniew
Dobrzycka, Agnieszka

Powiązania:

https://bibliotekanauki.pl/articles/41328230.pdf

Data publikacji:

2007

Wydawca:

Instytut Hodowli i Aklimatyzacji Roślin

Tematy:

lucerna
samoniezgodność
markery RAPD
podobieństwo genetyczne
alfalfa
self-incompatibility
RAPD markers
genetic similarity

Opis:

Celem pracy było określenie podobieństwa genetycznego 16 zróżnicowanych populacji lucerny za pomocą markerów molekularnych RAPD — PCR oraz ocena stopnia ich samoniezgodności. Badane obiekty utworzyły cztery grupy podobieństwa genetycznego, które wynosiło od 42% do 75%. Populacje o podobnym stopniu samoniezgodności nie znalazły się w tej samej grupie podobieństwa genetycznego. W celu zbadania samoniezgodności obserwowano wnikanie łagiewek pyłkowych do zalążni przy pomocy mikroskopu fluorescencyjnego. Na tej podstawie wyróżniono 4 populacje o wysokiej samoniezgodności (populacja Syn 7-3, linia F, mieszaniec F × B₁₀, mutant ‘tf’) i 5 populacji o niskiej samoniezgodności (populacja Syn 9-3, linia B₁₀, mieszaniec B₁₀ × F, odmiana Ulstar i mutant ‘lp’).
The study purpose was to analyse genetic similarity between 16 populations of alfalfa using RAPD molecular markers and to describe their self-incompatiblity. The examined objects formed four groups of genetical similarity, which ranged from 42% to 75%. The populations with similar level of self-incompatibility were not in the same group of genetical similarity. To study the self-incompatibility effects, penetration of pollen tubes into the ovaries was observed with the use of fluorescence microscope. According to this, four populations with high self-incompatibility (population Syn 7-3, line F, hybrid F × B₁₀, mutant ‘tf’) and five populations with low self-incompatibility (population Syn 9-3, line B₁₀, hybrid B₁₀ × F, Ulstar and mutant ‘lp’) were distinguished.

Źródło:

Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin; 2007, 245; 205-214
0373-7837
2657-8913

Pojawia się w:

Biuletyn Instytutu Hodowli i Aklimatyzacji Roślin

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 96.

Tytuł:

„Malá slova“ a jejich podíl na stylu mluvených projevů
„Small words“ and their contribution to the style of spoken discourse

Autorzy:

Hoffmannová, Jana

Powiązania:

https://bibliotekanauki.pl/articles/615663.pdf

Data publikacji:

2017

Wydawca:

Uniwersytet Opolski

Tematy:

spoken Czech
syntax
conversation
turn
parts of speech
particles
connectives
pronouns
interjections
discourse markers

Opis:

In contrast to written language, spoken utterances evince a much higher incidence of deictics, indefinite and pseudo-demonstrative pronouns, contact particles (phatic expressions), specific conjunctions and other connectives, interjections, fillers and hesitation sounds. Corpus-based data should make it possible to attempt a new typology of such expressions (of a broad category of “discourse markers”), independent of the traditional categorization of the parts of speech. The research of spoken Czech syntax must take into account these groups of lexical means that are innate to spoken discourse, i.e. this important area where lexis and syntax meet. Such words as the Czech jako, teda, jakoe, jakoby seem to be semantically vague or empty, but they have a special effect on the connectedness and cohesion of spoken discourse. Moreover, the syntax of spoken discourse has to be investigated in terms of its dialogic and processual nature, inevitably respecting the relationships between utterances and dialogue turns; that is why special attention must be given to “small words” employed at the beginning or end of various types of turns. Their participation in the turn-taking mechanismus, as well as other functions, demonstrates that the “small words” in most cases cannot be regarded as redundant expressions, and that they contribute to the style of spoken discourse.

Źródło:

Stylistyka; 2017, 26; 155-171
1230-2287
2545-1669

Pojawia się w:

Stylistyka

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 97.

Tytuł:

Cechy składniowe i semantyczne łacińskiego leksemu admodum
Syntactic and Semantic Features of the Latin Lexeme admodum

Autorzy:

Górska, Małgorzata

Powiązania:

https://bibliotekanauki.pl/articles/2119718.pdf

Data publikacji:

2011

Wydawca:

Katolicki Uniwersytet Lubelski Jana Pawła II. Towarzystwo Naukowe KUL

Tematy:

części mowy
klasy gramatyczne leksemów
leksemy nieodmienne
dopowiedzenia
partykuły
wykładniki gradacji
wykładniki aproksymacji
parts of speech
grammatical classes of lexemes
uninflected lexemes
contextual asyntagmatic lexemes
particles
markers of gradation
markers of approximation

Opis:

This paper attempts to give substantial detail to the linguistic description of the Latin lexeme admodum. A thorough analysis of the lexeme’s syntactic and semantic features leads the author to the conclusion that admodum is a grammatically polyfunctional lexeme, since it can be used as (1) contextual asyntagmatic lexemes (yes, indeed, by all means), (2) marker of gradation: a. marker of intensity (very); b. marker of completeness (definitely/fully/completely, etc.); (3) at the same time, admodum can also function as an marker of approximation (about, around, etc.)

Źródło:

Roczniki Humanistyczne; 2011, 58-59, 3; 197-210
0035-7707

Pojawia się w:

Roczniki Humanistyczne

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 98.

Tytuł:

Стилистика в свете типов речевой культуры

Autorzy:

Сиротинина, Ольга O.

Powiązania:

https://bibliotekanauki.pl/articles/1925911.pdf

Data publikacji:

2005

Wydawca:

Uniwersytet Opolski

Tematy:

stylistics
functional stylistics
literaiy stylistics
practical stylistics
types of speech culture
speech culture markers

Opis:

The рарег is focused оп different aspects of the соггеlatioп between stylistics аnd types of speech сulture. It is argued that апу kind of stylistics studies оnlу the highest type of speech culture common to people who have a perfect command of all language varieties. In other words, stylistics always deals exclusively with the accepted model of good speech. The first part of the paper concentrates on the essence of three branches of stylistics: functional stylistics, literary stylistics, and practical stylistics. Functional stylistics studies functional differentiation of standard language (the Russian equivalent of the English term standard language is numepamypmrn язык). Practical stylistics is aimed at choosing the best synonym.Literary stylistics analyses fictional texts whose authors make a maximum use of language resources. Only people of the fully functional type of speech culture can cope with the above-mentioned tasks.The second part of the paper is devoted to a study of the peculiarities of speech culture markers manifestation in different language varieties. A close analysis of extensive factual data has led the author to the conclusion that speech culture markers are most active in public and fiction discourse and least active in standardized documents and casual everyday conversation.

Źródło:

Stylistyka; 2005, 14; 209-218
1230-2287
2545-1669

Pojawia się w:

Stylistyka

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 99.

Tytuł:

Occupational daily walking steps have inverse relationship with papillary thyroid cancer risk and progression: a retrospective analysis

Autorzy:

Zhang, Chunling
Zhang, Li
Su, Yan
Xiang, Lei
Zhang, Qin
Zhang, Chunhong
Huan, Qin

Powiązania:

https://bibliotekanauki.pl/articles/28761990.pdf

Data publikacji:

2024-03-05

Wydawca:

Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi

Tematy:

biochemical markers
office workers
construction workers
papillary thyroid cancer
daily step counts
PTC stages

Opis:

Objectives Investigate the impact of daily occupational walking steps on the progression of papillary thyroid cancer (PTC), a topic hitherto underresearched. Material and Methods The authors analyzed the data from 800 individuals with PTC across stages 0–IV. Participants were evenly divided into 2 distinct occupational groups: office workers and construction workers (N = 400 each). Data included comprehensive records of daily walking steps, demographic information, and clinical indicators. Pearson’s correlation coefficients or analysis of variance (ANOVA) were employed to assess the linkage between daily walking steps and PTC risk and stage, as well as associated biochemical markers. Results The analysis revealed a significant inverse relationship between daily walking steps and PTC risk. A higher frequency of daily steps was associated with reduced chances of PTC onset and a lower diagnostic stage of the disease. This protective effect of physical activity was particularly pronounced in the construction worker cohort. Subsequent evaluations showed that construction workers who consistently logged higher daily steps had markedly lower levels of thyroid-stimulating hormone (TSH), free triiodothyronine, free thyroxine, thyroid peroxidase antibody, thyroglobulin antibody, and thyroglobulin (Tg). Notably, daily walking steps exhibited a strong inverse correlation with body mass index (BMI), age, PTC volumes, and levels of TSH and Tg across both occupational groups (ρ < –0.37). The increase in daily steps was associated with the reduction in PTC stages (p < 0.001). Conclusions The research underscores the potential benefits of increased daily walking steps, suggesting that they may play a protective role in reducing PTC risk and moderating its progression.

Źródło:

International Journal of Occupational Medicine and Environmental Health; 2024, 37, 1; 58-71
1232-1087
1896-494X

Pojawia się w:

International Journal of Occupational Medicine and Environmental Health

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 100.

Tytuł:

Selekcja genomowa w hodowli drzew leśnych - podstawowe założenia, problemy i perspektywy
Genomic selection in forest tree breeding - basic principles, problems and future prospects

Autorzy:

Żukowska, W.B.
Wójkiewicz, B.
Lewandowski, A.

Powiązania:

https://bibliotekanauki.pl/articles/978931.pdf

Data publikacji:

2020

Wydawca:

Polskie Towarzystwo Leśne

Tematy:

breeding value
genetic gain
genetic markers
marker−assisted selection
quantitative trait locus
single
nucleotide polymorphism

Opis:

All tree breeders cope with the same challenge of the very long time interval of a single breeding cycle. What is more, trees are long−lived, with desirable breeding traits expressing late during their life cycle. Increasing problems with climate change, globalization or economic growth have forced us to accelerate tree breeding and improve selection precision, both of which can be achieved by genomic selection (GS). The idea of GS was introduced nearly 20 years ago as an extension of marker−assisted selection (MAS) in order to advance breeding technologies using genetic markers. Unlike MAS, which exploits only a set of marker−trait associations, GS relies on a high number of genetic markers that are spread throughout the entire length of the genome. All markers effects are assessed simultaneously in order to build a precise model that allows prediction of genetic estimated breeding value of a particular individual using genetic data only. GS has already revolutionized dairy cattle breeding resulting in remarkable improvements across multiple traits and is becoming more and more common in crop production. We now know that genetic architecture of quantitative traits is complex, but recent advances in genomics have made it possible to deal with this problem in an unprecedented way. There are certain concerns regarding GS in forest tree species that include genotype−environment (G×E) interaction and the usefulness of the predictive model built up by GS in the next generation of trees. Nevertheless, experimental results obtained so far have shown that the genetic gain per unit time as well as selection precision can be substantially increased. Here we present the basic principles of GS for forest tree species, giving examples of studies carried out so far and discussing problems and future possibilities that GS may soon open up for forest tree breeders.

Źródło:

Sylwan; 2020, 164, 05; 384-391
0039-7660

Pojawia się w:

Sylwan

Dostawca treści:

Biblioteka Nauki

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