- Tytuł:
- Properties of the transmission-disequilibrium test for the detection of quantitative trait loci in livestock
- Autorzy:
-
Szyda, J
Liu, Z.
Wild, V. - Powiązania:
- https://bibliotekanauki.pl/articles/2044224.pdf
- Data publikacji:
- 1998
- Wydawca:
- Polska Akademia Nauk. Czytelnia Czasopism PAN
- Tematy:
-
transmission-disequilibrium test
German Holstein cattle
chromosome localization
milk production
power
simulated data
population
real data
detection
dairy cattle
simulation system - Opis:
- The transmission-disequilibrium test (TDT) is a model-free method to detect linkage between a marker and a trait locus. Originally developed to map disease genes in human genetics, this statistic has been recently extended to deal with quantitative characters. The emphasis of current research is on investigating statistical properties of the test applied to data from livestock populations. For various constellations of sample parameters, it is shown via simulation that the empirically derived null hypothesis distribution of TDT remains in good agreement with its asymptotic distribution while its power is satisfactory only for very close linkage. TDT is then applied to a real data set from milk production data of a dairy cattle population.
- Źródło:
-
Journal of Applied Genetics; 1998, 39, 4; 309-319
1234-1983 - Pojawia się w:
- Journal of Applied Genetics
- Dostawca treści:
- Biblioteka Nauki