Skocz do pozycji: 1.

Tytuł:

Opredelenie parametrov impulsnogo transformatora dlja obluchenija molochnojj zhelezy zhivotnykh krupnogo rogatogo skota
Determination of parameters pulse transformer for irradiation of mammary gland cattle

Autorzy:

Torchuk, M.
Mikhajjlova, L.
Dubik, V.
Slobodjan, S.

Powiązania:

https://bibliotekanauki.pl/articles/76755.pdf

Data publikacji:

2015

Wydawca:

Komisja Motoryzacji i Energetyki Rolnictwa

Tematy:

electromagnetic field
disease treatment
infectious disease
colostrum
immunoglobulin
newborn calf
mammary gland
cattle

Źródło:

Motrol. Motoryzacja i Energetyka Rolnictwa; 2015, 17, 5
1730-8658

Pojawia się w:

Motrol. Motoryzacja i Energetyka Rolnictwa

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 2.

Tytuł:

A short review on proteomics and its applications

Autorzy:

Chandrasekhar, K.
Dileep, A.
Lebonah, D.E.
Pramoda Kumari, J.

Powiązania:

https://bibliotekanauki.pl/articles/11309.pdf

Data publikacji:

2014

Wydawca:

Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN

Tematy:

proteomics
application
protein function
protein structure
stress condition
metabolism
2-D electrophoresis
disease treatment
novel protein

Opis:

Proteomics is the large scale of study of proteins, particularly their function and structure. Proteomics is an excellent approach for studying changes in metabolism in response to different stress conditions. In the present review focused on different types of techniques for the analysis of expressed proteins. The techniques includes 2-D gel electrophoresis, MALDI-TOF/MS etc., play a vital role for the analysis of novel proteins and their role in disease maintenance and treatment. The review also concentrated on applicative perspective of proteomics in the fields of biomedical, agriculture and food.

Źródło:

International Letters of Natural Sciences; 2014, 12, 1
2300-9675

Pojawia się w:

International Letters of Natural Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 3.

Tytuł:

Treatment of Patients with Giant Tumors in the Course of Recklinghausen Disease – Own Experience

Autorzy:

Fijałkowska, Marta
Antoszewski, Bogusław

Powiązania:

https://bibliotekanauki.pl/articles/1397013.pdf

Data publikacji:

2012-12-01

Wydawca:

Index Copernicus International

Tematy:

Recklinghausen disease
neurofibroma
surgical treatment

Opis:

Neurofibromatosis type 1 (NF-1, von Recklinghausen disease) is included in the group of diseases known as phacomatosis. Clinical diagnosis of Recklinghausen disease is based on the presence of 2 from 7 criteria developed by a panel of expert. So far effective strategy of treatment of patients with NF-1 is not developed. One method of treatment are surgical excisions. The aim of the study was to present own experience of treatment of patients with giant tumors in the course of Recklinghausen disease. Material and methods. The Department of Plastic, Reconstructive and Aesthetic Surgery of Medical University in Łódź has under care 34 patients with NF-1. Fifteen patients (8 females and 7 males) with giant tumors were included in this analysis. The patients age was from 6 to 57 years. In analyzed group a retrospective review of surgical treatment was carried out on the basis of patients’ medical documentation. Results. Ten from 15 analyzed patients were operated on in our Department and performed surgeries were aimed to partially reduce the tumors mass. Only one patient had his tumor excised in one-stage procedure, in rest of the patients the lesions were too extensive. Most patients in histopathological examinations were diagnosed with neurofibroma (8 patients), 1 - neurofibromaplexiforme and 1 - neurofibrolipoma. Conclusions. Unpredictable course of Recklinghausen disease causes that follow-up examinations are necessary. Treatment of such patients is particularly indicated when the tumor mass causes difficulty in patients daily habits or is life-threatening. Also it is worth to remember that delayed decision of surgical treatment unable excision of the whole tumor in one-stage procedure. This in turn causes the risk of tumor re-growing and/or developing of malignancy

Źródło:

Polish Journal of Surgery; 2012, 84, 12; 632-637
0032-373X
2299-2847

Pojawia się w:

Polish Journal of Surgery

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:

Treatment of inflammatory bowel disease (IBD) in dogs and cats

Autorzy:

Malewska, K.
Rychlik, A.
Nieradka, R.
Kander, M.

Powiązania:

https://bibliotekanauki.pl/articles/31766.pdf

Data publikacji:

2011

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

treatment
inflammatory bowel disease
dog
cat
animal disease
pathogenesis

Opis:

The treatment of inflammatory bowel disease (IBD) possesses numerous difficulties owing to the unclear etiology of the disease. This article overviews the drugs used in the treatment of IBD depending on the intensity of clinical symptoms (Canine Inflammatory Bowel Disease Activity Index and Canine Chronic Enterophaty Clinical Activity Index). Patients demonstrating mild symptoms of the disease are usually placed on an appropriate diet which may be combined with immunomodulative or probiotic treatment. In moderate progression of IBD, 5-aminosalicylic acid (mesalazine or olsalazine) derivatives may be administered. Patients showing severe symptoms of the disease are usually treated with immunosuppressive drugs, antibiotics and elimination diet. Since the immune system plays an important role in the pathogenesis of the disease, the advancements in biological therapy research will contribute to the progress in the treatment of canine and feline IBD in the coming years.

Źródło:

Polish Journal of Veterinary Sciences; 2011, 14, 1
1505-1773

Pojawia się w:

Polish Journal of Veterinary Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 5.

Tytuł:

Treatment of lower limb trophic ulcers using hyperbaric oxygenation

Autorzy:

Kulesza, T.
Mitrut, T.
Jojczuk, M.
Jaholkowski, L.
Nodalski, A.
Prystupa, A.

Powiązania:

https://bibliotekanauki.pl/articles/3341.pdf

Data publikacji:

2014

Wydawca:

Instytut Medycyny Wsi

Tematy:

human disease
venous disease
treatment
lower limb
trophic ulcer
hyperbaric oxygenation
hyperbaric treatment

Źródło:

Journal of Pre-Clinical and Clinical Research; 2014, 08, 1
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 6.

Tytuł:

Non-surgical and surgical treatment of lumbar degenerative disc disease in the course of peripheral neuropathy

Autorzy:

Wójcik, G.
Piskorz, J.
Iłżecka, J.
Nalepa, D.

Powiązania:

https://bibliotekanauki.pl/articles/2052372.pdf

Data publikacji:

2015

Wydawca:

Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej

Tematy:

degenerative disc disease
sciatic neuritis
surgical treatment
conservative treatment

Opis:

The aim of this article is to review current reports pertaining the effects of treating patients with diagnosed degenerative disc disease in the lumbosacral section of the spine. Materials and methods: the method of descriptive analysis was used. The research was conducted on the basis of materials from MEDLINE and EMBASE databases from the last ten years. The cases of patients with sciatic neuritis caused by degenerative disc disease undergoing conservative treatment, and similar group of patients treated surgically, were analysed. Conclusions: Conservative treatment lowers the intensity of pain, but does not improve the functional abilities of the spine. Surgical treatment gives good and quick therapeutic results, but its long-term effects do not seem better than in the case of conservative treatment. Moreover, surgical treatment may result in serious complications. In rare cases the condition results in a severe impairment of motor functions in legs and sphincter paralysis. Such patients should undergo immediate surgical treatment.

Źródło:

Health Problems of Civilization; 2015, 09, 3; 24-30
2353-6942
2354-0265

Pojawia się w:

Health Problems of Civilization

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 7.

Tytuł:

Seed treatment for control leaf spot diseases of spring wheat
Zwalczanie chorob grzybowych lisci za pomoca zapraw nasiennych w uprawie pszenicy jarej

Autorzy:

Krzyzinska, B
Glazek, M.
Maczynska, A.

Powiązania:

https://bibliotekanauki.pl/articles/28475.pdf

Data publikacji:

2005

Wydawca:

Polskie Towarzystwo Botaniczne

Tematy:

plant disease
treatment
wheat
prochloraz
seed treatment
spring wheat
leaf spot disease
leaf
plant protection
triadimenol
triticonazole
fungal disease

Opis:

In the years 2001 and 2002 at the Institute of Plant Protection Branch in Sośnicowice research work was performed on seed treatment with fungicides against leaf diseases of spring wheat cv. Ismena caused by pathogenic fungi: Blumeria graminis, Phaeasphaeria nodorum, Puccinia recondita i Pyrenophora tritici-repentis. Two variants of protection were included in the experiment: seed dressing with fungicides or seed dressing and single application of foliar spray at GS 49. At early growth stages of spring wheat a very high biological activity against powdery mildew, septoria leaf spot, brown rust and tan spot was recorded for seed dressing containing triticonazole+prochloraz. In the case of triadimenol+imazalil+fuberidazole only a weak, but long-lasting effect against brown rust and septoria leaf spot was observed. Leaf infection as well as 1000 grain mass and yield, in the experimental combination with using triticonazole+prochloraz were on the same level as in the experimental variant where after seed dressing with triadimenol+imazalil+fuberidazole plots were sprayed with tridemorf+epoxykonazole at GS 49. It was concluded that seed dressing preparation containing triticonazole+prochloraz constituted a good base for protection of spring wheat against foliar diseases.
W latach 2001-2002 w Instytucie Ochrony Roślin w Sośnicowicach prowadzono badania nad stosowaniem zapraw nasiennych w ochronie pszenicy jarej odmiany Ismena przed chorobami liści, których sprawcami są grzyby patogeniczne takie jak Blumeria graminis, Phaeasphaeria nodorum, Puccinia recondita i Pyrenophora tritici-repentis. W doświadczeniu zastosowano jako jedyną ochronę fungicydową zabieg zaprawiania ziarna siewnego lub zabieg zaprawiania oraz zabieg opryskiwania w fazie rozwojowej roślin GS 49. We wczesnych fazach rozwojowych roślin pszenicy jarej zaprawa zawierająca tritikonazol+prochloraz wykazała bardzo wysoką aktywność biologiczna w ograniczeniu występowania mączniaka prawdziwego, septoriozy, rdzy i brunatnej plamistości liści. Nie obserwowano ograniczającego wpływu preparatu zawierającego triadimenol+imazalil+fuberidazol na porażenie liści pszenicy jarej przez grzyb Blumeria graminis i Pyrenophora tritici-repentis, jedynie wykazywał on słabe działanie w ochronie liści pszenicy jarej przed rdzą brunatną i septoriozą do końca wegetacji. W kolejnych obserwacjach, porażenie liści oraz uzyskane zwyżki masy tysiąca ziaren i plonu, w kombinacji doświadczalnej z zastosowaniem preparatu zawierającego prochloraz i tritikonazol było na poziomie zastosowania fungicydu w terminie T2 (GS 49) po zaprawie zawierającej triadimenol+imazalil+fuberidazol. Zaprawa zawierająca tritikonazol i prochloraz stanowiła także lepszą podstawę do dalszej ochrony roślin pszenicy jarej co miało odzwierciedlenie w uzyskaniu najwyższego plonu ziarna i masy tysiąca ziaren pszenicy jarej.

Źródło:

Acta Agrobotanica; 2005, 58, 1
0065-0951
2300-357X

Pojawia się w:

Acta Agrobotanica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 8.

Tytuł:

Comparison of permethrin 2.5 % cream vs. Tenutex emulsion for the treatment of scabies

Autorzy:

Goldust, M.
Rozaee, E.
Raghifar, R.
Naghavi-Behzad, M.

Powiązania:

https://bibliotekanauki.pl/articles/5863.pdf

Data publikacji:

2013

Wydawca:

Polskie Towarzystwo Parazytologiczne

Tematy:

comparison
permethrin
cream
Tenutex emulsion
treatment
scabies
parasitic disease
skin disease

Źródło:

Annals of Parasitology; 2013, 59, 1
0043-5163

Pojawia się w:

Annals of Parasitology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 9.

Tytuł:

What do we know about Kimura disease?
Co powinniśmy wiedzieć o chorobie Kimury?

Autorzy:

Mrówka-Kata, Katarzyna
Pilarz, Łukasz B.
Stęplewska, Katarzyna
Gabriel, Andrzej
Czecior, Eugeniusz
Bronikowska, Izabela

Powiązania:

https://bibliotekanauki.pl/articles/1034840.pdf

Data publikacji:

2013

Wydawca:

Śląski Uniwersytet Medyczny w Katowicach

Tematy:

kimura’s disease
disease management
treatment
choroba kimury
przebieg choroby
leczenie

Opis:

This article describes Kimura’s disease as a rare case of lymphadenitis and reviews its epidemiology, clinical aspects, diagnosis and treatment methods. The role of surgical procedures was also underlined. Kimura disease is a rare and benign chronic inflammatory soft tissue disorder of unknown origin. The definitive histological description was published by Kimura et al. in 1948 and henceforth, the disease has born his name. Since that time, there has been a gradual increase in the number of reports. While most cases of Kimura disease have originated in China, Japan or Southeast Asia, there have been sporadic case reports from Europe and America. The data suggest that Kimura’s disease should be included in the list of differential diagnoses for all neck lymph node involvements. If a otolaryngologist maintains a high index of suspicion, an early diagnosis can be made to contribute to a more successful outcome of the disease.
Artykuł opisuje chorobę Kimury – rzadką przyczynę limfadenopatii, jej epidemiologię, objawy kliniczne, diagnostykę i leczenie, w tym leczenie chirurgiczne. Choroba Kimury jest rzadkim, łagodnym, przewlekłym zapaleniem tkanki łącznej nieznanego pochodzenia. Cechy histologiczne tej choroby zostały po raz pierwszy opisane przez Kimurę i wsp. w 1948 r. i nazwane jego nazwiskiem. Większość przypadków choroby Kimury pochodzi z Chin, Japonii bądź południowo-wschodniej Azji, natomiast nieliczne z Europy i Ameryki. Obraz kliniczny choroby nakazuje uwzględnienie jej w diagnostyce różnicowej powiększenia węzłów chłonnych szyi. Daje to możliwość pomyślnego wyleczenia.

Źródło:

Annales Academiae Medicae Silesiensis; 2013, 67, 1; 47-51
1734-025X

Pojawia się w:

Annales Academiae Medicae Silesiensis

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 10.

Tytuł:

Ivermectin vs. lindane in the treatment of scabies

Autorzy:

Goldust, M.
Rezaee, E.
Raghifar, R.
Naghavi-Behzad, M.

Powiązania:

https://bibliotekanauki.pl/articles/5661.pdf

Data publikacji:

2013

Wydawca:

Polskie Towarzystwo Parazytologiczne

Tematy:

ivermectin
oral ivermectin
treatment
scabies
lindane
skin disease
human disease

Źródło:

Annals of Parasitology; 2013, 59, 1
0043-5163

Pojawia się w:

Annals of Parasitology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 11.

Tytuł:

Current problems concerning parasitology and mycology with regard to diseases of the skin and its appendages

Autorzy:

Blaszkowska, J.
Wojcik, A.

Powiązania:

https://bibliotekanauki.pl/articles/5637.pdf

Data publikacji:

2012

Wydawca:

Polskie Towarzystwo Parazytologiczne

Tematy:

parasitology
mycology
human disease
skin disease
parasitosis
mycosis
diagnostics
treatment
fungi
parasite

Źródło:

Annals of Parasitology; 2012, 58, 3
0043-5163

Pojawia się w:

Annals of Parasitology

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 12.

Tytuł:

Mesenchymal stem cells for the treatment of complex perianal fistulas in patients with Crohn disease

Autorzy:

Borycka-Kiciak, Katarzyna
Pietrzak, Anna
Kielar, Maciej
Tarnowski, Wiesław

Powiązania:

https://bibliotekanauki.pl/articles/1391853.pdf

Data publikacji:

2020

Wydawca:

Index Copernicus International

Tematy:

Crohn’s disease
inflammatory bowel disease
mesenchymal stem cells
perianal fistula
treatment

Opis:

Treatment of perianal fistulizing Crohn’s disease is demanding and burdened with a high percentage of failures, which forces clinicians to search for new, more effective therapeutic options. One of these options is the use of adipose-derived mesenchymal stem cells in local administration. Due to their multipotentiality and complex mechanism of action, stem cells are the promising new therapeutic approach for the treatment-refractory complex perianal fistulas – demonstrating both high efficacy and a favorable safety profile. The paper presents current knowledge on the mechanisms of action and manner of administration of mesenchymal stem cells, as well as the effectiveness and safety of their use in the treatment of perianal Crohn’s disease based on available literature.

Źródło:

Polish Journal of Surgery; 2020, 92, 1; 38-47
0032-373X
2299-2847

Pojawia się w:

Polish Journal of Surgery

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 13.

Tytuł:

Principles of contemporary treatment in trichinellosis

Autorzy:

Kociecka, W

Powiązania:

https://bibliotekanauki.pl/articles/836768.pdf

Data publikacji:

2001

Wydawca:

Polskie Towarzystwo Parazytologiczne

Tematy:

parasitic disease
parasite
tropical disease
Trichinella
trichinellosis
treatment
host
clinical pathology

Opis:

Principles of trichinellosis treatment were presented, based on contemporary parasitologic and clinical criteria. Significance of the Trichinella sp. life cycle, phase of the invasion and the disease was presented. The role of anthelmintics was stressed, as drugs of choice in eradication of the intestinal phase and in prevention against development of the muscular phase. Role of glucocorticoids was described in suppression of acute clinical signs/symptoms. Pathology of the late period of trichinellosis and of the late invasion sequele were discussed.

Źródło:

Annals of Parasitology; 2001, 47, 2
0043-5163

Pojawia się w:

Annals of Parasitology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 14.

Tytuł:

Principles of contemporary treatment in trichinellosis

Autorzy:

Kocięcka, W.

Powiązania:

https://bibliotekanauki.pl/articles/2147898.pdf

Data publikacji:

2001

Wydawca:

Polskie Towarzystwo Parazytologiczne

Tematy:

parasitic disease
parasite
tropical disease
Trichinella
trichinellosis
treatment
host
clinical pathology

Opis:

Principles of trichinellosis treatment were presented, based on contemporary parasitologic and clinical criteria. Significance of the Trichinella sp. life cycle, phase of the invasion and the disease was presented. The role of anthelmintics was stressed, as drugs of choice in eradication of the intestinal phase and in prevention against development of the muscular phase. Role of glucocorticoids was described in suppression of acute clinical signs/symptoms. Pathology of the late period of trichinellosis and of the late invasion sequele were discussed.

Źródło:

Wiadomości Parazytologiczne; 2001, 47, 2; 177-183
0043-5163

Pojawia się w:

Wiadomości Parazytologiczne

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 15.

Tytuł:

New Trends in Non-Pharmacological Treatment of Alzeheimer’s Disease

Autorzy:

Tokovska, Miroslava
Rosenberg, Adriana

Powiązania:

https://bibliotekanauki.pl/articles/1197943.pdf

Data publikacji:

2018-02-01

Wydawca:

Akademia Ignatianum w Krakowie

Tematy:

non-pharmacological treatment
person centred care
Alzheimer's disease

Opis:

RESEARCH OBJECTIVE: The aim of this paper is to summarize the knowledge of non-pharmacological treatment in the care of people with Alzheimer’s disease. The contribution is theoretical and provides a suitable prerequisite for further examination of the subject matter, namely the need for quality education and the need to change the approach of care for people with Alzheimer’s disease. THE RESEARCH PROBLEM AND METHODS: The presented contribution approaches the preferred values of care such as coping, self-decision and identity from the clients perspective, as well as new trends in non-pharmacological treatment of Alzheimer’s. Based on the study of professional domestic and foreign literature of social, psychological and medical orientation, we approach selected non-pharmacological therapies. THE PROCESS OF ARGUMENTATION: After defining the goal of the contribution and the basic concepts of Alzheimer-type dementia, it follows (i) the theory of physical environment adaptation, (ii) Tom Kitwood’s approach to care and (iii) health promoting and preventive approach in the social-healthcare sector. A substantial part of the argumentation is the need to create a new culture of care provision. RESEARCH RESULTS: The result of this argumentation is the need for quality preparation of future generations of healthcare professionals and the need for a change in the philosophy and culture of providing care for people with dementia in the countries of Eastern and Central Europe. CONCLUSIONS, INNOVATIONS AND RECOMMENDATIONS: This analysis confirms the need to change the attitudes and self-reflection of helping professionals in the care of people with Alzheimer’s disease. There is also an urgent need to change the preparation of future generations of assisting professionals and further education in line with the latest research and knowledge on the provision of social and health care.

Źródło:

Horyzonty Wychowania; 2017, 16, 40; 97-111
1643-9171
2391-9485

Pojawia się w:

Horyzonty Wychowania

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 16.

Tytuł:

Acceptance of illness after surgery in patients with breast cancer in the early postoperative period

Autorzy:

Nowicki, Andrzej
Krzemkowska, Elżbieta
Rhone, Piotr

Powiązania:

https://bibliotekanauki.pl/articles/1394286.pdf

Data publikacji:

2015

Wydawca:

Index Copernicus International

Tematy:

breast cancer
surgical treatment
acceptance of the disease

Opis:

The breast cancer is the most common cancer in women, both in Poland and in the world. Consequences entail a disruption in the physical, psychological and social functioning. The aim of the study was to assess the acceptance of illness by patients treated for breast cancer in the early postoperative period. Material and methods. The research was conducted on the group of 100 consecutive patients aged 32‑80 years (median 56 years) who underwent surgery for breast cancer in the Centre of Oncology in Bydgoszcz w 2014 roku. 68 of women had mastectomy, 32 of women had conservative surgery. Polling was conducted in the early period after surgery. The original questionnaire containing closed questions the scale of acceptance of the disease (AIS) as well as mental adaptation to cancer (Mini-Mac) was used in the study. Results. 38% of patients had high acceptance of the disease, 48% averageand 14% had low acceptance. Patients after conservative surgery had a higher average values for the mental strategies to cope with the disease, for the fighting spirit (23.1), helplessness and hopelessness (13.5), positive revaluation (23), the patients had a lower average (16.5) in the strategy to absorb anxiety. Patients after conservative surgery had a higher average for constructive style (2.6) but lower for destructive style (1.5). High level of mental coping with the disease was observed in 53%of patients with constructive style and 4% of patients with destructive style. While, a low level of mental coping with the dosease was observed in 5% of patients with constructive style and 46% of patients with destructive style. Conclusions. Almost half of women after mastectomy or conservative surgery had an average acceptance of the disease. The disease was accepted best by educated women living in the cities, whitecollar workers with a good economic situation. The following factors were affected the better management of the disease, in order: age, education, current occupation and economic situation, while the type of surgery did not affect better management. More than half of women, regardless of the type of surgery reflected the high level of constructive style.

Źródło:

Polish Journal of Surgery; 2015, 87, 11; 539-550
0032-373X
2299-2847

Pojawia się w:

Polish Journal of Surgery

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 17.

Tytuł:

Herbal medicine for treatment and prevention of liver diseases

Autorzy:

Rajaratnam, M.
Prystupa, A.
Lachowska-Kotowska, P.
Zaluska, W.
Filip, R.

Powiązania:

https://bibliotekanauki.pl/articles/3402.pdf

Data publikacji:

2014

Wydawca:

Instytut Medycyny Wsi

Tematy:

human disease
herbal medicine
treatment
prevention
liver disease
medicinal plant
hepatoprotective herb
herb

Opis:

The rising number of patients with liver dysfunction due to overwhelming usage of drugs and alcohol has paved the path for researchers in an interest in herbal medicine. This is because there are only a few universally effective and available options for the treatment of common liver diseases, such as cirrhosis, fatty liver and chronic hepatitis. Herbal treatment has been used to alleviate disorders related to liver and other internal organs for many centuries in the eastern world, and have currently become a favourable therapy internationally for pathological liver conditions. In recent years, researchers have used scientific methods to evaluate the effects of plants for the treatment of liver ailments, although in many cases the mechanisms and modes of action of these plants, as well as their therapeutic effectiveness, have not been confirmed. Several hundred plants have been examined to-date, but only a handful has been studied thoroughly. Among these, the current study discusses a compilation of herbal medicines used for liver protection, such as Silymarin (milk thistle), Liv-52, Camellia sinensis (green tea), Glycyrrhizaglabra (licorice) and FuzhengHuayu. The increasing use of herbal medicines reflects their perceived effectiveness in the treatment and prevention of disease, and the belief that these treatments are safe because they are ‘natural’. The presented study evaluates the effects of herbal extracts in the treatment of liver diseases, provides a general understanding of the actions of herbal medicines, a background for understanding the hepatoprotectiveness of herbs, and the challenges that are faced by the scientific community in researching thoroughly of each and every compounds of the herbs.

Źródło:

Journal of Pre-Clinical and Clinical Research; 2014, 08, 2
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 18.

Tytuł:

A child with a rare genetic disease - Noonan syndrome

Autorzy:

Siwik, P.
Janas, A.

Powiązania:

https://bibliotekanauki.pl/articles/3700.pdf

Data publikacji:

2015

Wydawca:

Instytut Medycyny Wsi

Tematy:

child
human disease
rare disease
genetic disease
Noonan syndrome
autosomal dominant congenital disorder
surgical treatment

Opis:

Noonan syndrome is a congenital developmental disorder characterized by short stature, facial dysmorphia, congenital heart defects and skeletal anomalies, with as estimated incidence of between one per 1000 and one per 2500 live births. The aim of our study is to present a case of dental surgical treatment of a child with such disorder. It is widely reported that children with mental disabilities receive less dental and medical care than their nondisabled counterparts. Because of this problem, it seems justified to describe the procedures of treating such children with dental issues, basing on a case of a girl with Noonan Syndrome.

Źródło:

Journal of Pre-Clinical and Clinical Research; 2015, 09, 1
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 19.

Tytuł:

Uveitis in dog and cats
Zapalenie błony naczyniowej oka u psa i kota

Autorzy:

Trbolova, A.

Powiązania:

https://bibliotekanauki.pl/articles/9904.pdf

Data publikacji:

2011

Wydawca:

Okulistyka Weterynaryjna

Tematy:

animal disease
eye disease
cat
dog
eye
uveitis
iridocyclitis
choroiditis
uveal tract
disease etiology
treatment

Opis:

  W skład błony naczyniowej oka wchodzi: tęczówka, ciało rzęskowe oraz naczyniówka. Proces zapalny dotyczyć może całej błony naczyniowej jak też tylko ich fragmentów np. tęczówki, ciała rzęskowego lub naczyniówki. Na odpowiedź immunologiczną oka wpywają liczne struktury gałki ocznej. Klasyfikacja zapaleń błony naczyniowej oka opiera się na podstawie zmian anatomicznych, obrazu klinicznego oraz etiologii. Na podstawie tego wyróżniamy ; zapalenie odcinka przedniego,  zapalenie części pośredniej, zapalenie odcinka tylnego lub zapalenie całej błony naczyniowej. Zapalenie może mieć charakter ostry lub przewlekły. najczęstsze przyczyny zapaleń błony naczyniowej oka  to; towarzyszące chorobom układowym, infekcje, inwazje pasożytnicze, pierwotniakowe, urazy mechaniczne, nowotwory, czynniki immunologiczne. Często ustalenie etiologii jest niemożliwe i określane jest terminem zapalenia idiopatycznego. objawem zapalenia jest zaczerwienienie gałki ocznej, bolesność, silnie zwężona źrenica, niskie ciśnienie płynu wewnątrzocznego oraz zmętnienie cieczy w przedniej komorze oka. W leczeniu stosuje się kilka grup leków. Są to leki rozszezrzające źrenicę, steroidy, niesterydowe leki przeciwzapalne, antybiotyki oraz leki immunosupresyjne. Im silniejsza reakcja zapalna, tym terapia powinna być prowadzona mocniejszymi lekami, które też należy stosować ze zwiększoną częstotliwością.

Źródło:

Okulistyka Weterynaryjna. e-kwartalnik dla lekarzy i studentów weterynarii; 2011, 3
2082-9256

Pojawia się w:

Okulistyka Weterynaryjna. e-kwartalnik dla lekarzy i studentów weterynarii

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 20.

Tytuł:

Statement of the expert group on the current practice and prospects for the treatment of complex perirectal fistulas in the course of Crohn’s disease

Autorzy:

Banasiewicz, Tomasz
Eder, Piotr
Rydzewska, Grażyna
Reguła, Jarosław
Dobrowolska, Agnieszka
Durlik, Marek
Wallner, Grzegorz

Powiązania:

https://bibliotekanauki.pl/articles/1392381.pdf

Data publikacji:

2019

Wydawca:

Index Copernicus International

Tematy:

Crohn's disease
perianal fistula
surgical treatment of fistulas
biological treatment
stem cells

Opis:

Perirectal fistulas in the course of Crohn’s disease (CD) constitute an important problem in this group of patients. They are observed in a vast majority of patients with involvement through colorectal inflammation. Perirectal fistulas in CD present a great diagnostic and therapeutic challenge due to the intensified clinical symptoms and worse prognosis than in the case of crypt originating fistulas. The condition for implementation of effective treatment of perirectal fistulas in the course of CD is the correct diagnosis, defining the anatomy of fistulas, presence of potential stenoses and inflammation in the gastrointestinal tract. Treatment of these fistulas is difficult and requires close cooperation between the colorectal surgeon and the gastroenterologist. The combination of surgical and pharmacological treatment has higher efficacy compared to surgical treatment or pharmacotherapy alone. In conservative treatment, aminosalicylates and steroids are of minor importance, while chemotherapeutics, antibiotics, and thiopurines find application in daily clinical practice. TNF-α neutralizing antibodies such as infliximab (IFX), adalimumab (ADA) or certolizumab (CER) prove to be the most effective. Surgical treatment may be provided as ad hoc; in this case, drainage procedures are recommended, usually with leaving a loose seton. Planned procedures consist in the excision of fistulas (simple fistulas) or performing more complex procedures, such as advancement flaps or ligation of the intersphincteric fistula tract Surgical measures can be complemented by the use of video technology (video-assisted anal fistula treatment VAAFT) or vacuum therapy. In extreme cases, it may be necessary to create the stoma. Treatment of perirectal fistulas includes adhesives or so-called plugs. High hopes may be associated with the introduction of stem cells into clinical practice, which is the administration of non-hematopoietic multipotent cells to the fistulas to induce the phenomenon of immunomodulation and tissue healing.

Źródło:

Polish Journal of Surgery; 2019, 91, 1; 38-46
0032-373X
2299-2847

Pojawia się w:

Polish Journal of Surgery

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 21.

Tytuł:

Impact of biological treatment on intestinal microbiom in children with Crohn’s disease

Autorzy:

Krawczyk, Agnieszka
Sroka-Oleksiak, Agnieszka
Kowalska-Duplaga, Kinga
Fyderek, Krzysztof
Gosiewski, Tomasz
Salamon, Dominika

Powiązania:

https://bibliotekanauki.pl/articles/1177355.pdf

Data publikacji:

2018

Wydawca:

Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN

Tematy:

Crohn’s disease
biological treatment
children
gut microbiota

Opis:

Crohn’s disease (CD) is a chronic, inflammatory illness of the digestive tract, characterized by alternating periods of remission and recurrence. The pathogenesis of CD is still unclear but probably is a result of a complex interaction between immunological, genetic and microbiological disorders. In recent years, there has been an increasing extent of evidence that gut microbiota plays a very important role in the pathogenesis of CD. Currently, the most effective treatment is biological therapy using anti-TNF monoclonal antibodies. It is interesting whether biological drugs resulting in fast remission, contributes to the normalization of the gut microbiota. Due to the fact that the children’s population is a significant percentage of all patients with CD, it is important to pay close attention to the problem of microbiological disorders in this age group. The aim of this study was to investigate whether there are quantitative changes of chosen bacteria species and fungi of the genus Candida in children with Crohn's disease relative to healthy children and assesment of quantitative changes in patients after biological treatment. In the group of children with Crohn’s disease, the numbers in Candida were significantly higher (9.74×1017 CFU/g) than in the control group (9.35×1010 CFU/g, p = 0.011). Biological therapy led to a significant reduction in the amount Candida (5.91×1011) and was comparable with the number in the control group. In the case of bacteria, we observed an increase in S. marcescens (3,4×108) in the patients group compared to the controls (1,85×108) and an increase in L. fermentum (2,34×1010) in relation to healthy children (3,31×108, p = 0,048) Biological treatment had an impact on the decrease in L. fermentum (4,76×109, p = 0.05).

Źródło:

World Scientific News; 2018, 104; 245-256
2392-2192

Pojawia się w:

World Scientific News

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 22.

Tytuł:

Severe gynaecomastia associated with spironolactone treatment in a patient with decompensated alcoholic liver cirrhosis - case report

Autorzy:

Schab, K.
Prystupa, A.
Mulawka, D.
Mulawka, P.

Powiązania:

https://bibliotekanauki.pl/articles/3042.pdf

Data publikacji:

2015

Wydawca:

Instytut Medycyny Wsi

Tematy:

gynaecomastia
spironolactone
treatment
patient
alcoholic disease
liver cirrhosis

Opis:

Gynaecomastia is uni- or bilateral breast enlargement in males associated with benign hyperplasia of the glandular, fibrous and adipose tissue resulting from oestrogen-androgen imbalance. Asymptomatic gynaecomastia is a common finding in healthy male adults and does not have to be treated, while symptomatic gynaecomastia might be the symptoma of many pathological conditions and requires meticulous diagnosis and therapeutic management. The commonest causes of gynaecomastia in the Polish population include liver cirrhosis and drugs used to treat its complications. The current study presents the case of severe painless gynaecomastia in a patient with decompensated alcoholic liver cirrhosis, treated with spironolactone because of ascites. Breast enlargement assessed a IIb according to the Simon’s Scale or III according to the Cordova-Moschella classification, developed slowly over the two-year period of low-dose spironolactone therapy The course and dynamics of disease are described and the main mechanisms leading to its development discussed. The importance of effective treatment of patients with severe gynecomastia is emphasized as the disease may result in significant psychosocial problems.

Źródło:

Journal of Pre-Clinical and Clinical Research; 2015, 09, 1
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 23.

Tytuł:

Double blind study of sertaconazole 2% cream vs. clotrimazole 1% cream in treatment of seborrheic dermatitis

Autorzy:

Goldust, M.
Rezaee, E.
Rouhani, S.

Powiązania:

https://bibliotekanauki.pl/articles/6533.pdf

Data publikacji:

2013

Wydawca:

Polskie Towarzystwo Parazytologiczne

Tematy:

sertaconazole
cream
clotrimazole
treatment
seborrheic dermatitis
human disease

Źródło:

Annals of Parasitology; 2013, 59, 1
0043-5163

Pojawia się w:

Annals of Parasitology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 24.

Tytuł:

Gastroesophageal reflux disease – from the point of view of a gastroenterologist, otolaryngologist and surgeon

Autorzy:

Jurkiewicz, Dariusz
Waśko-Czopnik, Dorota
Pietruszewska, Wioletta
Tarnowski, Wiesław
Barańska, Magda
Kowalczyk, Magdalena
Jaworski, Paweł

Powiązania:

https://bibliotekanauki.pl/articles/1397276.pdf

Data publikacji:

2021

Wydawca:

Index Copernicus International

Tematy:

diagnosis
Gastroesophageal reflux disease
pharmacological and surgical treatment

Opis:

Gastrooesophageal reflux disease is the regurgitation of stomach contents into the esophagus, which causes troublesome symptoms or complications for the patient. Before starting the treatment, it is always necessary to objectively confirm gastroesophageal reflux disease, especially in correlation with ENT symptoms, as extra esophageal complications. In diagnostics, the "gold standard" is a 24-hour impedance-pH supplemented with endoscopy. Treatment without objective confirmation of the disease is not recommended, the more so that non-acid gas proximal reflux, detectable only in the MIIpH test, causes the greatest number of laryngological complications. It is important to confirm the coexistence of clinical symptoms of GERD with ESS. Considering the time of treating the disease and its consequences, it is worthwhile to be cautious and careful with the diagnosis of the disease, and the treatment should be carried out for a long time in relation to the recommendation, preferably in cooperation with an ENT specialist and gastroenterologist. The greatest therapeutic effectiveness is achieved by combining PPI with itopride while maintaining the appropriate doses of drugs and observing a sufficiently long duration of treatment, while maintaining the correct dose reduction and drug discontinuation regimen. In case of failure of pharmacological treatment, antireflux surgery should be take into consideration.

Źródło:

Polish Journal of Otolaryngology; 2021, 75, 2; 42-50
0030-6657
2300-8423

Pojawia się w:

Polish Journal of Otolaryngology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 25.

Tytuł:

The occurrence of resveratrol in foodstuffs and its potential for supporting cancer prevention and treatment. A review

Autorzy:

Dybkowska, E.
Sadowska, A.
Swiderski, F.
Rakowska, R.
Wysocka, K.

Powiązania:

https://bibliotekanauki.pl/articles/873404.pdf

Data publikacji:

2018

Wydawca:

Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny

Tematy:

occurrence
resveratrol
foodstuff
potential
human disease
cancer
prevention
treatment

Opis:

Over recent years, there has been increasing interest noted in those active substances derived from plants that show potential for preventing cancer development. The most promising candidate is resveratrol which can be found in large amounts in the skin of grapes, tomatoes and in red wine. Its beneficial effects on the human body are seen both in prevention and therapy. The anti-carcinogenic action of resveratrol is linked with its ability to neutralise reactive oxygen species and to modulate cellular processes such as apoptosis, and both cancerous cell proliferation and differentiation. This article presents the characteristics of resveratrol as a bioactive compound derived from natural sources exhibiting anti-cancer properties, which, because of a wide spectrum of biological activities may be used in the prevention of cancer. Many in vitro and animal-based studies have demonstrated such preventative anti-cancer action in the colon, prostate, breast and lungs. The beneficial effects of resveratrol are also presented when adopted as a support to conventional treatments of cancer using chemo- and radio-therapy.
W ciągu ostatnich lat wzrosło zainteresowanie biologicznie czynnymi związkami pochodzenia roślinnego, które mogłyby ograniczyć rozwój chorób nowotworowych. Do najważniejszych z nich zalicza się resweratrol, występujący w większej ilości w skórce winogron, pomidorów i czerwonym winie. Resweratrol wykazuje korzystne oddziaływanie profilaktyczne i terapeutyczne na organizm. Przeciwnowotworowe działanie reswerastrolu związane jest z jego zdolnością do neutralizowania reaktywnych form tlenu oraz modulującym oddziaływaniem na procesy apoptozy, proliferacji i różnicowania komórek nowotworowych. Niniejsza praca przedstawia charakterystykę resweratrolu jako związku bioaktywnego pochodzenia naturalnego o działaniu przeciwnowotworowym, który dzięki szerokiemu spektrum działania biologicznego może mieć zastosowanie w chemoprewencji nowotworów. Przeciwnowotworowa aktywność tego związku została dowiedziona w licznych badaniach in vitro oraz na zwierzętach, w których wykazano działanie zapobiegawcze resweratrolu w stosunku do nowotworów: jelita grubego, gruczołu krokowego, piersi, a także płuc. Przedstawiono również jego korzystne oddziaływanie wspomagające standardowe leczenie nowotworów przy zastosowaniu chemioterapii i radioterapii.

Źródło:

Roczniki Państwowego Zakładu Higieny; 2018, 69, 1
0035-7715

Pojawia się w:

Roczniki Państwowego Zakładu Higieny

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 26.

Tytuł:

Streptococcus suis: a re-emerging pathogen associated with occupational exposure to pigs or pork products. Part I - epidemiology

Autorzy:

Dutkiewicz, Jacek
Sroka, Jacek
Zając, Violetta
Wasiński, Bernard
Cisak, Ewa
Sawczyn, Anna
Kloc, Anna
Wójcik-Fatla, Angelina

Powiązania:

https://bibliotekanauki.pl/articles/991187.pdf

Data publikacji:

2017

Wydawca:

Instytut Medycyny Wsi

Tematy:

streptococcus suis
pigs
humans
carriage
disease
epidemiology
treatment
prevention

Opis:

Streptococcus suis (ex Elliot 1966, Kilpper-Bälz & Schleifer 1987) is a facultatively anaerobic Gram-positive ovoid or coccal bacterium surrounded by a polysaccharide capsule. Based on the antigenic diversity of the capsule, S. suis strains are classified serologically into 35 serotypes. Streptococcus suis is a commensal of pigs, commonly colonizing their tonsils and nasal cavities, mostly in weaning piglets between 4–10 weeks of age. This species occurs also in cattle and other mammals, in birds and in humans. Some strains, mostly those belonging to serotype 2, are also pathogenic for pigs, as well as for other animals and humans. Meningitis is the primary disease syndrome caused by S. suis, both in pigs and in humans. It is estimated that meningitis accounted for 68.0% of all cases of human disease reported until the end of 2012, followed by septicaemia (including life-threatening condition described as ‘streptococcal toxic shock-like syndrome’ – STSLS), arthritis, endocarditis, and endophthalmitis. Hearing loss and/or vestibular dysfunction are the most common sequelae after recovery from meningitis caused by S. suis, occurring in more than 50% of patients. In the last two decades, the number of reported human cases due to S. suis has dramatically increased, mostly due to epidemics recorded in China in 1998 and 2005, and the fulminant increase in morbidity in the countries of south-eastern Asia, mostly Vietnam and Thailand. Out of 1,642 cases of S. suis infections identified between 2002–2013 worldwide in humans, 90.2% occurred in Asia, 8.5% in Europe and 1.3% in other parts of the globe. The human disease has mostly a zoonotic and occupational origin and occurs in pig breeders, abattoir workers, butchers and workers of meat processing facilities, veterinarians and meat inspectors. Bacteria are transmitted to workers by close contact with pigs or pig products, usually through contamination of minor cuts or abrasions on skin of hands and/or arms, or by pig bite. A different epidemiologic situation occurs in the Southeast Asian countries where most people become infected by habitual consumption of raw or undercooked pork, blood and offal products in the form of traditional dishes. Prevention of S. suis infections in pigs includes vaccination, improvement in pig-raising conditions, disinfection and/or fumigation of animal houses, and isolation of sick animals at the outbreak of disease. Prevention of human infections comprises: protection of skin from pig bite or injury with sharp tools by people occupationally exposed to pigs and pig products, prompt disinfection and dressing of wounds and abrasions at work, protection of the respiratory tract by wearing appropriate masks or repirators, consulting a doctor in the case of febrile illness after exposure to pigs or pork meat, avoidance of occupations associated with exposure to pigs and pork by immunocompomised people, avoidance of consumption of raw pork or pig blood, adequate cooking of pork, and health education.

Źródło:

Annals of Agricultural and Environmental Medicine; 2017, 24, 4
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 27.

Tytuł:

Multiple sclerosis and pregnancy – treatment considerations

Autorzy:

Kamieniak, M.P.
Wolanin, N.
Jarosz, P.
Kobialka, I.
Kosmider, K.
Petit, V.
Rejdak, K.

Powiązania:

https://bibliotekanauki.pl/articles/2098207.pdf

Data publikacji:

2020

Wydawca:

Instytut Medycyny Wsi

Tematy:

multiple sclerosis
chronic inflammatory disease
pregnancy
neurology
gynaecology
treatment

Opis:

Multiple sclerosis is a chronic inflammatory disease which, due to the destruction of the fibres of the central nervous system in the process of demyelination, leads to numerous neurological symptoms and progressive disability. The disease is autoimmune, which means that myelin is destroyed by the patient’s own cells, caused by improper functionong and regulation of the immune system. Multiple sclerosis affects more and more people and is therefore a significant clinical problem which, to a large Entent, affects women, especially in childbearing age This presents a big challenge for carrying out pregnancy while continuing the therapy, ensuring the safety of the foetus and simultaneously achieving the best possible therapeutic effect. The decision whether the therapy should be continued or whether it should be eliminatedis usually made according to assessment of the possible gains and losse. Despite the lack of clear indications, there are many studies proving the relative safety of the use of individual but not all the drugs during pregnancy. Pregnancy, however, has a fairly good impact on the development of multiple sclerosis, and that safety considerations, especially those concerning the growing foetus, force a decision to change or completely suspend the therapy. In-depth research on the already available and emerging therapeutic pathways in multiple sclerosis bring hope for increasingly better results in the future in the treatment of pregnant patients with multiple sclerosis.

Źródło:

Journal of Pre-Clinical and Clinical Research; 2020, 14, 4; 126-129
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 28.

Tytuł:

The use of diode lasers in non-surgical therapy of periodontitis

Autorzy:

Kulinska-Michalska, M.M.
Cwiklinska, N.
Lisiecka, M.
Czaplicka-Szydlik, P.
Lewkowicz, N.

Powiązania:

https://bibliotekanauki.pl/articles/2098214.pdf

Data publikacji:

2020

Wydawca:

Instytut Medycyny Wsi

Tematy:

periodontal disease
periodontitis
therapy
treatment
bacterial biofilm
scaling
root planing
laser treatment
photodynamic therapy
nonsurgical treatment
patient

Opis:

Introduction. Periodontitis is a disease of multifactorial etiology and complex clinical manifestation. Removal of subgingival bacterial biofilm is a fundamental procedure in the treatment of periodontitis. Scaling and root planing (SRP) is currently the gold standard in the treatment of periodontitis, but in some cases such a procedure does not provide satisfactory results. The use of lasers in the treatment of periodontitis is one of the alternative adjunctive methods that has recently become more popular. Objective. The aim of the study was to evaluate the effectiveness of diode lasers in the treatment of periodontitis, based on the literature found in the Medline, Pubmed and Scopus databases published from June 2013 – June 2020. Results were based on a comparison of the effectiveness of SRP treatment in combination with photodynamic therapy or SRP in combination with laser irradiation of periodontal pockets. Results. The majority of studies confirmed the effectiveness of periodontal treatment combining SRP with photodynamic therapy or SRP with laser irradiation, compared to an SRP alone. Conclusions. Based on the recent literature, it can be concluded that SRP combined with photodynamic therapy or SRP in combination with a diode laser irradiation are effective methods to improve the outcomes of non-surgical periodontal treatment.

Źródło:

Journal of Pre-Clinical and Clinical Research; 2020, 14, 4; 169-173
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 29.

Tytuł:

Diabetes and depression: a combination of civilization and life-style diseases is more than simple problem adding - literature review

Autorzy:

Dziemidok, P,
Makara-Studzinska, M.
Jarosz, M.J.

Powiązania:

https://bibliotekanauki.pl/articles/52014.pdf

Data publikacji:

2011

Wydawca:

Instytut Medycyny Wsi

Tematy:

human disease
diabetes
depression
life style
complication
patient
treatment

Źródło:

Annals of Agricultural and Environmental Medicine; 2011, 18, 2
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 30.

Tytuł:

Review of traditional and natural methods of treating Alzheimer’s disease

Autorzy:

Mieczkowski, Maurycy
Sieja, Krzysztof
Stępień-Słodkowska, Marta

Powiązania:

https://bibliotekanauki.pl/articles/1055246.pdf

Data publikacji:

2016

Wydawca:

Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego

Tematy:

Alzheimer disease
Herbal Medicine
Nutrition
Pharmacological Treatment
Physical Activity

Opis:

The most common form of dementia in the elderly population is Alzheimer’s disease (AD). World Health Organization (WHO) thus defines Alzheimer’s disease: “a set of neurodegenerative brain symptoms, resulting in progressive impairment of memory, thinking, cognition, counting, language, ability to learn and assessing situations, which disturb everyday life”. It usually develops in 65+-yearolds, and the risk of AD in 85+-year-olds is as high as 50%. It has become a considerable threat to the society, given the longer life expectancy and an increase in the retirement-aged population. AD prevention and treatment methods described in this paper are still being developed and perfected. Studies on genesis of the disease aim at comprehensive understanding of its causes. New, alternative treatment methods are still sough. Researchers develop and test biomarkers that could facilitate early diagnosis.

Źródło:

Central European Journal of Sport Sciences and Medicine; 2016, 16, 4; 67-75
2300-9705
2353-2807

Pojawia się w:

Central European Journal of Sport Sciences and Medicine

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 31.

Tytuł:

The gut immune system, inflammatory bowel diseases, and the body immune homeostasis: modern treatment strategies

Autorzy:

Actis, G.C.

Powiązania:

https://bibliotekanauki.pl/articles/1918372.pdf

Data publikacji:

2016

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

Inflammatory bowel disease
gut immunopathology
gut apoptosis
IBD modern treatment

Opis:

The digestive tract is nowadays conceived as a barrier organ constituted by a mucosal membrane separating the gut lumen from the inner milieu. The gut lumen is laden by a myriad of antigens brought about by the diet, but also pertaining to the overwhelming bacterial species of the gut microbiome. The mucosal cell population comprehends epithelial cells, and a variety of immune reactive cells. Of them, the mononuclear types effecting innate responses are endowed by membrane signaling receptors and, as a rule, are sensing the polysaccharides of bacterial cell walls; non-tolerated signals may then push the chain reaction on, to end in full activation of inflammation mediators. Acquired immunity is in turn mainly effected by T-cell types, some of them, behaving as autoreactive cells, may induce metastatic inflammation beyond bowel boundaries, partly explaining the so-called extra-intestinal manifestations of inflammatory bowel disease (IBD). The scenario is further complicated by the possible influence of epigenetic factors: diet, stress, smoking, drugs. Being IBD a low-penetrance disorder, for the full phenotype to develop, a critical mass of the above listed factors (typically, a disturbed membrane permeability, an immune stimulus, and an epigenetic factor) must occur. In the century since the full description of IBD, a variegated plethora of measures have been attempted. Some updated designs are now under scrutiny. Microbiota engineering, apoptosis modulation, and diet modification are just a few of the measures that we are arbitrarily describing here.

Źródło:

Progress in Health Sciences; 2016, 6(2); 165-174
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 32.

Tytuł:

Efficient plant regeneration of bittersweet [Solanum dulcamara L.], a medicinal plant

Autorzy:

Mutlu, E C
Turker, A.U.

Powiązania:

https://bibliotekanauki.pl/articles/57857.pdf

Data publikacji:

2008

Wydawca:

Polskie Towarzystwo Botaniczne

Tematy:

plant regeneration
bittersweet
Solanum dulcamara
medicinal plant
skin disease
treatment

Opis:

Solanum dulcamara L. (bittersweet) is a medicinal plant that has been used to treat skin diseases, warts, tumors, felons, arthritis, rheumatism, bronchial congestion, heart ailments, ulcerative colitis, eye inflammations, jaundice and pneumonia. A reliable in vitro culture protocol for bittersweet was established. Explants (leaf and petiole segments) were cultured on Murashige and Skoog minimal organics (MSMO) medium with various plant growth regulator combinations. Leaf explants formed more shoots than petiole explants. Plant regeneration was observed through indirect organogenesis with both explants. Best shoot proliferation was obtained from leaf explants with 3 mg/l BA (benzyladenine) and 0.5 mg/l IAA (indole-3-acetic acid). Regenerated shoots were transferred to rooting media containing different levels of IAA (indole-3-acetic acid), IBA (indole-3-butyric acid), NAA (naphthalene acetic acid) or 2,4-D (2,4 dichlorophenoxyacetic acid). Most shoots developed roots on medium with 0.5 mg/l IBA. Rooted explants were transferred to vermiculate in Magenta containers for acclimatization and after 2 weeks, they were planted in plastic pots containing potting soil and maintained in the plant growth room.

Źródło:

Acta Societatis Botanicorum Poloniae; 2008, 77, 4; 275-280
0001-6977
2083-9480

Pojawia się w:

Acta Societatis Botanicorum Poloniae

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 33.

Tytuł:

A double blind study of the effectiveness of sertaconazole 2% cream vs. metronidazole 1% gel in the treatment of seborrheic dermatitis

Autorzy:

Goldust, M.
Rezaee, E.
Raghifar, R.

Powiązania:

https://bibliotekanauki.pl/articles/6631.pdf

Data publikacji:

2013

Wydawca:

Polskie Towarzystwo Parazytologiczne

Tematy:

effectiveness
sertaconazole
metronidazole
gel
patient
treatment
seborrheic dermatitis
human disease

Źródło:

Annals of Parasitology; 2013, 59, 4
0043-5163

Pojawia się w:

Annals of Parasitology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 34.

Tytuł:

Dexpanthenol in the treatment of corneal disorders and injuries
Dekspantenol w leczeniu schorzeń i urazów rogówki

Autorzy:

Szumny, Dorota
Misiuk-Hojło, Marta

Powiązania:

https://bibliotekanauki.pl/articles/2159014.pdf

Data publikacji:

2022-09-30

Wydawca:

Medical Education

Tematy:

dexpanthenol
cornea
disease
injury
treatment
dekspantenol
rogówka
choroba
uraz
leczenie

Opis:

Dexpanthenol - a precursor to vitamin B5 - is a compound of natural origin that has a long-known beneficial effect on skin and mucous membrane hydration and epithelial healing. Its anti-inflammatory activity is also used in treatment. Its effects on superficial tissues have been observed in numerous in vitro and in vivo studies, but the exact mechanism of action has not yet been understood. In ophthalmology, dexpanthenol is a well-known and widely used drug in patients with acute and chronic diseases of the ocular surface, as well as for treating the sequelae of corneal injuries.
Dekspantenol – prekursor witaminy B5 – jest związkiem pochodzenia naturalnego, który ma znany od dawna dobroczynny wpływ na nawilżenie skóry i błon śluzowych oraz na gojenie się nabłonków. W leczeniu wykorzystuje się również jego aktywność przeciwzapalną. Wpływ dekspantenolu na tkanki powierzchowne był obserwowany w licznych badaniach in vitro i in vivo, jednak dokładny mechanizm działania nie został do tej pory poznany. W okulistyce dekspantenol jest znanym i szeroko stosowanym lekiem u pacjentów z ostrymi i przewlekłymi chorobami powierzchni oka oraz następstwami urazów rogówki.

Źródło:

OphthaTherapy; 2022, 9, 3; 195-199
2353-7175
2543-9987

Pojawia się w:

OphthaTherapy

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 35.

Tytuł:

Factors affecting the course of Graves orbitopathy and poor response to glucocorticoid treatment followed by orbital radiotherapy

Autorzy:

Jagiełło-Korzeniowska, Agnieszka
Sokołowski, Andrzej
Hubalewska-Dydejczyk, Alicja
Romanowska-Dixon, Bożena
Bałdys-Waligórska, Agata

Powiązania:

https://bibliotekanauki.pl/articles/2159024.pdf

Data publikacji:

2022-05-19

Wydawca:

Medical Education

Tematy:

Graves' orbitopathy
Graves' disease
TRAb
NOSPECS
glucocorticoid treatment
orbital radiotherapy

Opis:

Graves’ orbitopathy is a rare autoimmune disorder characterized by the inflammation of orbital tissues. The course of disease can be described in terms of its activity and severity. Aim: The aim of our study was to determine the factors affecting the activity and severity of Graves’ orbitopathy, as well as to identify the predictive factors of poor response to glucocorticoid treatment followed by orbital irradiation. Methods: We performed a prospective observational study of 214 patients with Graves’ orbitopathy who were divided into two groups depending on the treatment they had previously obtained for their Graves’ disease. They received i.v. methylprednisolone pulses followed by orbital radiotherapy. They were examined and had their TSH, TRAb and FT4 levels evaluated prior to treatment and after 1, 6 and 12 months. Results: A pre-treatment TRAb concentration higher by one unit (U/L) implied a mean increase in the relative risk of active orbitopathy by 4.7% (p = 0.0362). A TRAb concentration higher by one U/L 1 month after treatment implied a mean increase in the relative risk of moderate-to-severe and severe GO by 8.7% (p = 0.0167) 6 months after treatment. As regards poor response to treatment, patients with moderate-to-severe and severe Graves’ orbitopathy on admission carried a higher risk of being non-responders. Each point scored on the NOSPECS scale prior to treatment increased the relative risk of the patient being a non-responder by 30%. Conclusions: Patients with higher TRAb levels have a higher risk of active Graves’ orbitopathy and moderate-to-severe and severe Graves’ orbitopathy. Monitoring TRAb serum concentration in those patients is of great importance. Patients with more severe Graves’ orbitopathy carry a higher risk of being poor responders to immunosuppressive treatment. Therefore, careful monitoring of patients with Graves’ orbitopathy and their early referral to specialized centers is essential.

Źródło:

OphthaTherapy; 2022, 9, 2; 98-105
2353-7175
2543-9987

Pojawia się w:

OphthaTherapy

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 36.

Tytuł:

Surgical Cost of Care in Crohn’s Disease

Autorzy:

Keller, Deborah S.
Katz, Jeffry
Stein, Sharon L.
Delaney, Conor P.

Powiązania:

https://bibliotekanauki.pl/articles/1396392.pdf

Data publikacji:

2013-09-01

Wydawca:

Index Copernicus International

Tematy:

Crohn’s disease
cost of treatment
surgical management
biologic therapy

Opis:

The aim of the studywas to evaluate the cost of surgical care and short-term outcomes of Crohn’s disease(CD) in the era of laparoscopy and biologic therapy. Material and methods. Review of a prospective database identifiedCD patients that underwent surgical management. Patients were stratified into laparoscopic, open, and converted approaches. Main outcome measures were short-term patient outcomes and cost of care by approach. Results. 92 patients were analyzed- 63.1% laparoscopic, 32.6% open, 4.3% converted. The majority was elective (100% converted, 94.8% laparoscopic, 90% open) and segmental resections (75% converted, 70.7% laparoscopic, 43.3% open). Operative times were similar between laparoscopic and open (152 minutes and 138 minutes, respectively). More open patients required ICU care (20% versus 12.1% laparoscopic and 0% converted). The median LOS was 3 (1-25) days laparoscopic, 4 (1-29) open and 4 (3-8) converted. The laparoscopic complication rate was 15.5%, readmission rate 12.1%, and reoperation rate 8.6%. The mean total hospital cost was $9,702 laparoscopic, $10,782 open, and $13,293 for converted cases (US Dollars). Conclusions. Laparoscopy is appropriate for most CD cases. When necessary to combine with open surgery, this results in efficient and effective patient outcomes and healthcare utilization. These results are important when weighing the cost of ongoing medical therapy versus surgical intervention.

Źródło:

Polish Journal of Surgery; 2013, 85, 9; 511-516
0032-373X
2299-2847

Pojawia się w:

Polish Journal of Surgery

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 37.

Tytuł:

Physical therapy vs. medical treatment of musculoskeletal disorders in dentistry - a randomised prospective study

Autorzy:

Nemes, D.
Amaricai, E.
Tanase, D.
Popa, D.
Catan, L.
Andrei, D.

Powiązania:

https://bibliotekanauki.pl/articles/49449.pdf

Data publikacji:

2013

Wydawca:

Instytut Medycyny Wsi

Tematy:

physical therapy
medical treatment
musculoskeletal disorder
dentistry
rehabilitation
assessment
absenteeism
work absenteeism
musculoskeletal disease
human disease

Opis:

Introduction and objective. Musculoskeletal disorders are frequently met in dentistry. Objectives. To show the efficiency of rehabilitation and to make correlations among patients’ pain levels, their overall health status, and the number of days of work absenteeism. Materials and method. A total of 390 dentists diagnosed with low back pain, scapulohumeral periarthritis, cervicobrachial neuralgia, hand osteoarthritis, tendinitis or tenosynovitis of the upper limb, carpal tunnel syndrome, spinal deformities and fibromyalgia, were followed in a 2-year prospective study. For each ailment the patients were divided into two groups. Group 1 followed both medical and rehabilitation treatment, while group 2 followed medical treatment. The patients were assessed by the visual analogue scale (VAS), the Health Assessment Questionnaire adapted for Dentists (HAQD) and the number of days of absenteeism. Results. VAS scores did not significantly differ between the two groups at the beginning of the study but were significantly lower at final assessment. HAQD scores were significantly lower at one-year and two-year assessments in Group 1. The number of days of absenteeism did not differ significantly between the two groups at the initial assessment. Nevertheless, the number of days of absenteeism was significantly higher for Group 2 patients at the end of the study. For increased values of the visual analogue scale at the beginning and at the end of the study, the significantly increased numbers of days of absenteeism and of health assessment questionnaire scores were associated. Conclusions: Improvements of functional parameters and increase in work productivity were recorded in dentists who followed physical therapy.

Źródło:

Annals of Agricultural and Environmental Medicine; 2013, 20, 2
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 38.

Tytuł:

Feline herpesvirus-1: Ocular manifestations, diagnosis and treatment options
Choroby oczu kotów wywołane zakażeniami herpesvirusem-1: Objawy kliniczne, diagnostyka i sposoby leczenia

Autorzy:

Gould, D.

Powiązania:

https://bibliotekanauki.pl/articles/9976.pdf

Data publikacji:

2012

Wydawca:

Okulistyka Weterynaryjna

Tematy:

cat
animal disease
feline herpesvirus 1
diagnosis
treatment
ocular manifestation
keratitis
conjunctivitis
animal exposure
ocular disease

Opis:

W swojej pracy autor przedstawia kluczowe aspekty związane z chorobami oczu występującymi u kotów, które  powoduje  herpesvirus  koci typu 1. Praca  w obszerny sposób omawia wiele chorób implikowanych tym typem wirusa. szczegółowo opisuje objawy kliniczne poszczególnych schorzeń, diagnostykę oraz doradza w sposób praktyczny dobieranie odpowiedniego leczenia. Mamy podany szereg leków wraz z dawkami i sposobami ich podania dla poszczególnych schematów leczenia. Praca jest bogato ilustrowana fotografiami obrazującymi konkretne przypadki kliniczne. Autor włożył wiele wysiłku, dzięki czemu powstała naprawdę wspaniała praca naukowa, która praktykom daje gotowy schemat rozpoznawania i leczenia tych trudnych z punktu klinicznego chorób.
Practical relevance Feline herpesvirus-1 (FHV-1) is a major cause of feline morbidity. Following exposure to the virus, virtually all cats become persistently infected and many of these will develop recrudescent disease on one or more occasions during their life. Ocular manifestations include conjunctivitis, corneal ulceration and keratitis. In severe cases the condition can be blinding. Global importance FHV-1 has a worldwide distribution, with reported exposure rates in some cat populations of up to 97%. As such it is a significant cause of clinical disease in the global cat population. Patient Group Young and adolescent cats are most at risk of acute primary disease, and the vast majority of these will then become persistently infected. Around half of all persistently infected cats will shed virus at some stage in their life and these may develop recrudescent ocular disease. Clinical challenges Acute ocular herpetic disease can be severe and painful. Repeated bouts of recrudescent ocular disease can lead to progressive corneal pathology that can be ultimately blinding in affected cats. Treatment of FHV-1 ocular disease is challenging. Antiviral medications may be expensive and require good owner and patient compliance. Clinical responses in patients can be variable. Selecting the appropriate therapeutic approach requires good clinical judgement and depends on a number of factors such as severity and stage of clinical disease, patient and owner compliance and financial considerations. Evidence base Although a wide range of antiviral treatments are available, very few of these have been tested in controlled clinical trials. Instead, therapeutic decisions are often made based on results of in vitro studies, case-based reports and anecdote. Large, masked, controlled clinical trials are required in order to determine the efficacy of the antiviral drugs currently available to treat FHV-1.

Źródło:

Okulistyka Weterynaryjna. e-kwartalnik dla lekarzy i studentów weterynarii; 2012, 2
2082-9256

Pojawia się w:

Okulistyka Weterynaryjna. e-kwartalnik dla lekarzy i studentów weterynarii

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 39.

Tytuł:

Etiology, symptoms and treatment of uterine torsion in domestic animals
Etiologia, objawy kliniczne oraz leczenie skrętu macicy u zwierząt domowych

Autorzy:

Kacprzak, K.J.
Jurka, P.
Max, A.
Czerniawska-Piatkowska, E.
Bartyzel, B.J.

Powiązania:

https://bibliotekanauki.pl/articles/82780.pdf

Data publikacji:

2014

Wydawca:

Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie

Tematy:

animal disease
domestic animal
uterine torsion
bitch
cow
mare
treatment

Opis:

Skręt macicy to schorzenie występujące u prawie wszystkich zwierząt domowych dość rzadko, z wyjątkiem bydła. Problem ten występuje najczęściej w drugiej połowie ciąży lub w trakcie porodu jako przyczyna niestosunku porodowego. Opisywany jest jako skręcenie się narządu prostopadłe do jego osi długiej. Nie wyjaśniono w wystarczający sposób etiologii tej choroby, wydaje się jednak, iż czynnikiem ryzyka predysponującym do skrętu jest niestabilność ciężarnej macicy. Zewnętrzne objawy kliniczne nie są specyficzne. Diagnozy problemu dokonuje się poprzez badanie przez pochwę, badanie rektalne oraz metodami obrazowania jamy brzusznej. U zwierząt gospodarskich leczenie ukierunkowane jest na pozostawienie funkcjonującej macicy, w związku z czym postępowanie chirurgiczne nie jest techniką z wyboru. Wykorzystuje się takie metody, jak ręczne odkręcanie narządu przez pochwę, użycie drążka odkręcającego oraz przetaczanie zwierzęcia przez jego oś długą. Jeżeli przedstawione sposoby okażą się nieskuteczne, wykonywany jest zabieg operacyjny. U psów i kotów postępowaniem z wyboru jest leczenie chirurgiczne. Do niedawna preferowanym postępowaniem u małych zwierząt był zabieg usunięcia macicy wraz z jajnikami, co uniemożliwiało dalszy rozród tych zwierząt. Obecnie stosuje się również nową technikę – jednostronne usunięcie jajnika i rogu macicy.
Uterine torsion is a non-common problem in almost all domestic animals other than cattle. It occurs mainly in the second half of pregnancy or at parturition as a cause of dystocia. Torsion is described as twisting of the uterus perpendicular to its long axis. The etiology of this condition is still not well known but it seems that instability of the gravid uterus is a possible risk factor. External signs are nonspecific. The condition is diagnosed by vaginal inspection, rectal palpation and abdominal imaging. In farm animals the treatment is aimed at the saving of the uterus and to this reason, non-surgical methods are mainly preferred. They include manual detorsion per vaginam, use of detorsion rod and rolling the animal along its longitudinal axis. If ineffective, surgical methods are applied. Conversely, in dogs and cats surgical methods are the treatment of choice. Until recently the total ovariohysterectomy was preferred which was terminating animals’ reproductive ability. Now new technique, unilateral ovariohysterectomy – ovariocornuectomy is being used as well.

Źródło:

Folia Pomeranae Universitatis Technologiae Stetinensis. Agricultura, Alimentaria, Piscaria et Zootechnica; 2014, 32
2081-1284

Pojawia się w:

Folia Pomeranae Universitatis Technologiae Stetinensis. Agricultura, Alimentaria, Piscaria et Zootechnica

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 40.

Tytuł:

Metody i vozmozhnosti primenenija ehlektronnykh sistem dlja povyshenija immuniteta novorozhdennykh zhivotnykh
Methods and abilities of usage electrical systems in increasing process of newborn animals immunity

Autorzy:

Garasymchuk, I.
Potapskijj, P.
Pancir, Y.
Gordijjchuk, I.

Powiązania:

https://bibliotekanauki.pl/articles/76915.pdf

Data publikacji:

2015

Wydawca:

Komisja Motoryzacji i Energetyki Rolnictwa

Tematy:

newborn animal
immunity
physiological characteristics
infectious disease
treatment
electromagnetic field

Źródło:

Motrol. Motoryzacja i Energetyka Rolnictwa; 2015, 17, 5
1730-8658

Pojawia się w:

Motrol. Motoryzacja i Energetyka Rolnictwa

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 41.

Tytuł:

Treatment of the follicular cyst of the mandible in a pregnant woman - a case study

Autorzy:

Gaweda, A.
Jach, E.
Tomaszewski, T.
Wojciechowicz, J.

Powiązania:

https://bibliotekanauki.pl/articles/3372.pdf

Data publikacji:

2011

Wydawca:

Instytut Medycyny Wsi

Tematy:

human disease
treatment
follicular cyst
mandible
pregnant woman
retained tooth

Źródło:

Journal of Pre-Clinical and Clinical Research; 2011, 05, 1
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 42.

Tytuł:

In vitro and in vivo evaluation of antitrypanosomal activity of Annona muricata stem bark extracts
Badanie działania wyciągu z kory Annona muricata przeciw śpiączce afrykańskiej in vitro i in vivo

Autorzy:

Onyeyili, P.A.
Aliyoo, K.

Powiązania:

https://bibliotekanauki.pl/articles/72585.pdf

Data publikacji:

2015

Wydawca:

Instytut Włókien Naturalnych i Roślin Zielarskich

Tematy:

in vitro evaluation
in vivo evaluation
Annona muricata
stem bark
plant extract
human disease
animal disease
Chagas disease
antitrypanosomal activity
treatment

Opis:

The control of trypanosomosis in animals and humans based on chemotherapy is limited and not ideal, since the agents used are associated with severe side effects, and emergence of relapse and drug resistant parasites. The need for the development of new, cheap and safe compounds stimulated this study. Three concentrations (211, 21.1 and 2.11 mg per ml) of chloroform stem bark extract of Annona muricata were screened for trypanocidal activity against Trypanosoma brucei brucei in vitro. Also, two doses (200 mg per kg and 100 mg per kg) of the extract were evaluated for trypanocidal activity in rats infected with the parasite. Haematological parameters were determined on day 1 post infection and on days 1, 6 and 30-post extract treatment. The extracts inhibited parasite motility and totally eliminated the organisms at the concentrations used in vitro. The extract also showed promising in vivo trypanocidal activity. The observed in vitro and in vivo trypanocidal activities may be due to the presence of bioactive compounds present in the extracts as seen in this study. The extract also improved the observed decreases in haematological parameters of the treated rats, which may be due to their ability to decrease parasite load. The observed oral LD50 of 1,725.05 mg per kg of the chloroform A. muricata extract using up and down method is an indication of very low toxicity, implying that the extract could be administered with some degree of safety.
Leczenie chemioterapeutykami śpiączki afrykańskiej, tak u ludzi jak i u zwierząt, jest trudne ze względu na powstawanie wielu poważnych objawów niepożądanych oraz wywoływanie zjawiska oporności podczas ich stosowania, co powoduje brak skuteczności i pojawianie się nawrotów tej choroby. Stąd potrzeba znalezienia nowego skutecznego i taniego leku była powodem podjęcia badań przedstawianych w tej pracy. Celem badań było określenie aktywności wyciągu chloroformowego z kory Annona muricata stosowanego w warunkach in vitro dla trzech stężeń (211, 21,1 i 2,11 mg/ml) przeciwko aktywności Trypanosoma brucei brucei. Ponadto w badaniach in vivo określano aktywność tego ekstraktu w dwóch dawkach (100 i 200 mg/kg) u szczurów zarażonych pasożytem. Do oceny stanu zwierząt wykorzystano pomiar odpowiednich parametrów hematologicznych po 1 dniu od ich zainfekowania oraz po 1, 6 i 30 dniu podawania badanego wyciągu. W badaniach in vitro we wszystkich zastosowanych stężeniach wyciąg hamował ruchliwość omawianego pasożyta. Ponadto w badaniach in vivo ekstrakt całkowicie eliminował obecność Trypanosoma brucei brucei u zainfekowanych zwierząt, wykazując w ten sposób obiecującą aktywność przeciwko trypanosomatozie. Zaobserwowane działanie, tak in vitro jak i in vivo, było być może związane z obecnością związków czynnych charakteryzujących stosowany wyciąg. Analizowany ekstrakt, prawdopodobnie ze względu na obniżenie liczby pasożytów po jego podawaniu, miał także zdolność poprawiania parametrów hematologicznych u zainfekowanych zwierząt. Ze względu na otrzymaną wartość LD50 dla zastosowanego wyciągu chloroformowego z kory Annona muricata, wynoszącą 1725,05 mg/kg po podaniu dożołądkowym szczurom, można sądzić, że stosowanie badanego wyciągu jest względnie bezpieczne.

Źródło:

Herba Polonica; 2015, 61, 2
0018-0599

Pojawia się w:

Herba Polonica

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 43.

Tytuł:

Phytochemical and pharmacological aspects of Nothapodytes nimmoniana. An overview
Profil fitochemiczny i farmakologiczny Nothapodytes nimmoniana. Przegląd

Autorzy:

Khan, N.
Tamboli, E.T.
Sharma, V.K.
Kumar, S.

Powiązania:

https://bibliotekanauki.pl/articles/72676.pdf

Data publikacji:

2013

Wydawca:

Instytut Włókien Naturalnych i Roślin Zielarskich

Tematy:

phytochemistry
pharmacology
Nothapodytes nimmoniana
Icacinaceae
camptothecin
medicinal property
human disease
treatment

Opis:

Nothapodytes nimmoniana (J. Graham) (Icacinaceae), commonly known as Amruta is found in India particularly in Maharashtra, Goa, Kerala, Assam, Jammu and Kashmir as well as Tamilnadu areas. It is an important medicinal plant, the major source of a potent alkaloid, namely camptothecin, of a wide spectrum of pharmacological activities like anti-cancer, anti-HIV, antimalarial, antibacterial, anti-oxidant, anti-inflammatory, anti-fungal and also applied in the treatment of anaemia. Camptothecin is still not synthesized, therefore, its production entirely depends on natural sources. N. nimmoniana is one such plant which yields contain camptothecin in significantly high amount. The plant is gaining international recognition due to its diversified medicinal uses. It is subjected to excessive harvest. It has been categorized as a vulnerable and endangered plant. The present review encompasses the phytochemical, analytical, pharmacological, biotechnological, and other specific aspects of N. nimmoniana.
Nothapodytes nimmoniana (J. Graham) (Icacinaceae), powszechnie znana jako Amruta, rośnie w Indiach, szczególnie w prowincjach Maharashtra, Goa, Kerala, Assam, Dżammu i Kaszmir, a także na niektórych obszarach Tamilnadu. Jest jedną z ważnych roślin leczniczych, głównym źródłem silnego alkaloidu, kamptotecyny, mającej szerokie spektrum działania: przeciwnowotworowe, anty-HIV, antymalaryczne, antybakteryjne, przeciwutleniające, przeciwzapalne, przeciwgrzybicze. Znajduje również zastosowanie w leczeniu anemii. Jak dotąd kamptotecyna nie została zsyntetyzowana, dlatego jej produkcja całkowicie zależy od źródeł naturalnych. N. nimmoniana jest jedną z roślin zawierających duże ilości kamptotecyny. Zyskała ona międzynarodowe uznanie dzięki szerokiemu spektrum zastosowań, co powoduje zwiększenie jej eksploatacji. Z tego powodu została uznana za gatunek zagrożony. Poniższy przegląd obejmuje badania fitochemiczne, analityczne, farmakologiczne, biotechnologiczne i inne prowadzone nad gatunkiem N. nimmoniana.

Źródło:

Herba Polonica; 2013, 59, 1
0018-0599

Pojawia się w:

Herba Polonica

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 44.

Tytuł:

Strategie aktywnej i pasywnej immunizacji jako terapii choroby Alzheimera
Active and passive immunization strategies as treatments of Alzheimer’s disease

Autorzy:

Sobów, Tomasz

Powiązania:

https://bibliotekanauki.pl/articles/1059141.pdf

Data publikacji:

2008

Wydawca:

Medical Communications

Tematy:

Ab
Alzheimer’s disease
immunization
treatment
choroba alzheimera
leczenie
immunizacja
amyloid

Opis:

Currently available pharmacotherapeutics (cholinesterase inhibitors and memantin) for Alzheimer’s disease (AD) exert mainly symptomatic effect and doubtful, if any, disease-modifying activities. Strategies of active and passive immunization were very successful in the last 10 years, mainly, however, with the use of experimental animal models of the disease. More recently, several human trials have been undertaken with mixed results obtained. Some support was found for the idea that immunotherapy may influence natural disease history, at least at the level of neuropathology and biomarkers and, to the less extend, neuroimaging findings and cognition. The paper presents recent developments in the use of immunotherapy of AD both with animal pasywmodels as well as human clinical trials. An attempt is also made to elucidate possible mechanisms of action of this novel treatment approach. Particularly, the difficulties in translating results obtained in animal studies into clinical trials in humans has been underlined and discussed. The results of the very first human trial with the use of AN-1792 vaccination are critically discussed with special reference to the possible mechanisms of the observed severe complications of this treatment modality (brain inflammation). currently, several other studies with active immunization are on the way, in which novel technologies diminishing the risk of brain inflammation were used. Finally, article presents several clinical trials with the use of passive immunization strategies, showing the advantages of this approach, particularly in the context of tolerability.
Obecnie dostępne metody leczenia choroby Alzheimera (inhibitory cholinesterazy i memantyna) mają prawdopodobnie głównie działanie objawowe, a ich wpływ na naturalny przebieg choroby jest wątpliwy. Strategie aktywnej i pasywnej immunizacji są intensywnie badane przez ostatnie 10 lat. Wyniki badań eksperymentalnych oraz wstępne wyniki badań chorych z AD wskazują, że działanie immunoterapii może wykraczać poza efekt objawowy i wpływać nie tylko na objawy (poznawcze, behawioralne), ale także na progresję neuropatologiczną i, prawdopodobnie, biomarkery. W pracy przedstawiono wyniki badań z wykorzystaniem modeli zwierzęcych AD i użyciem metod aktywnej i pasywnej immunizacji anty-Ab. Omówiono trudności z przełożeniem wyników uzyskanych z wykorzystaniem zwierząt laboratoryjnych na potencjalne metody terapeutyczne u ludzi. Opisano ponadto pierwsze wyniki badań na ludziach i podjęto próbę odpowiedzi na pytanie o mechanizmy działania immunoterapii w AD. Krytycznej analizie poddano wyniki pierwszych badań klinicznych na ludziach z użyciem szczepionki AN-1792, ze szczególnym uwzględnieniem możliwych przyczyn obserwowanych w tych badaniach powikłań (zapalenie mózgu). Obecnie prowadzonych jest kilka innych badań z aktywną immunizacją, w których zastosowano technologie zmniejszające ryzyko zapalenia mózgu. W pracy omówiono także prowadzone obecnie próby kliniczne z wykorzystaniem technik pasywnej immunizacji i wskazano na potencjalne przewagi tej metody nad immunizacją aktywną, zwłaszcza w kontekście tolerancji leczenia.

Źródło:

Aktualności Neurologiczne; 2008, 8, 2; 77-83
1641-9227
2451-0696

Pojawia się w:

Aktualności Neurologiczne

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 45.

Tytuł:

Malting barley seed health depending on different fungicide treatment
Stan zdrowotny ziarna jęczmienia browarnego w zależności od sposobu ochrony przed chorobami

Autorzy:

Majchrzak, B.
Dubis, B.
Okorski, A.

Powiązania:

https://bibliotekanauki.pl/articles/27058.pdf

Data publikacji:

2008

Wydawca:

Polskie Towarzystwo Botaniczne

Tematy:

plant disease
malting barley
grain
barley
seed
seed health
fungicide treatment

Opis:

Field studies were carried out in the 2004 – 2005 growing seasons. The mycological analysis of malting barley (varieties Prestige and Sezam) grains was performed twice: on seeds stored for 30 days and on seeds stored for fi ve months. The infl uence of fungicide treatment on species diversity and the amount of fungal pathogens on kernels of both varieties of malting barley were determined in the studies. Main fungal pathogens of both varieties of malting barley were fi eld fungal species, such as: Alternaria alternata, Epicocum purpurascens, and fungi of the genus Fusarium. The extension of the grain storage period to fi ve months resulted in an increased share of pathogenic species.
Badania polowe prowadzono w latach 2004- 2005. Analizę mikologiczną nasion jęczmienia browarnego Prestige i Sezam wykonywano 2 krotnie: na ziarnie przechowywanym przez 30 dni oraz na ziarnie przechowywanym przez okres pięciu miesięcy. W badaniach stwierdzono wpływ ochrony fungicydowej na skład gatunkowy i liczebność grzybów zasiedlających ziarno obu odmian jęczmienia browarnego. Ziarno obydwu odmian jęczmienia browarnego zasiedlone było przede wszystkim przez gatunki grzybów polowych: Alternaria alternata, Epicoccum purpurascens oraz grzyby z rodzaju Fusarium. Wydłużenie okresu przechowywania ziarna do 5 miesięcy spowodowało wzrost udziału gatunków patogenicznych.

Źródło:

Acta Agrobotanica; 2008, 61, 2
0065-0951
2300-357X

Pojawia się w:

Acta Agrobotanica

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 46.

Tytuł:

Treatment of scabies: The topical ivermectin vs. permethrin 2.5% cream

Autorzy:

Goldust, M.
Rezaee, E.
Raghifar, R.
Hemayat, S.

Powiązania:

https://bibliotekanauki.pl/articles/5545.pdf

Data publikacji:

2013

Wydawca:

Polskie Towarzystwo Parazytologiczne

Tematy:

human disease
treatment
scabies
topical ivermectin
permethrin cream
mite
Sarcoptes scabiei

Źródło:

Annals of Parasitology; 2013, 59, 2
0043-5163

Pojawia się w:

Annals of Parasitology

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 47.

Tytuł:

Monitoring of plasma concentration of pyrimethamine (PYR) in infants with congenital Toxoplasma gondii infection – own observations
Monitorowanie stężenia pirymetaminy w surowicy krwi u niemowląt z wrodzonym zarażeniem Toxoplasma gondii – obserwacje własne

Autorzy:

Lipka, B.
Milewska-Bobula, B.
Filipek, M.

Powiązania:

https://bibliotekanauki.pl/articles/837604.pdf

Data publikacji:

2011

Wydawca:

Polskie Towarzystwo Parazytologiczne

Tematy:

monitoring
plasma concentration
pyrimethamine
infant
Toxoplasma gondii
infection
congenital disease
treatment

Opis:

The study objective was to determine plasma concentration of pyrimethamine in 24 infants aged 1–5 months, treated for congenital toxoplasmosis. Pyrimethamine was used in a single daily dose at an amount of 0.35–0.98 mg/kg daily, with sulfadiazine (50–100 mg/kg/day) in divided doses 2–3 times a day, and folinic acid given twice a week (7.5 mg). This regimen was continued for 2–6 months, then Fansidar® was administered. Pyrimethamine concentration in plasma was measured using high-performance liquid chromatography method (HPLC). A total of 70 tests were performed. Concentration of pyrimethamine ranged from 0.01 to 1.2 μg/ml. In 14 children (58 tests) the concentration of pyrimethamine achieved therapeutic value. In 7 patients (8 tests) the concentration was below therapeutic level, and in 3 patients (4 tests) above therapeutic level. In 11/24 (46%) children transient moderate neutropenia was observed. Modification of therapy was necessary in 12 patients. Monitoring of pyrimethamine concentration in plasma improves safety and effectiveness of the therapy and is useful in obtaining correct individual dose of the drug. Neutropenia is the most common side-effect of pyrimethamine observed even when using the recommended dose.

Źródło:

Annals of Parasitology; 2011, 57, 2
0043-5163

Pojawia się w:

Annals of Parasitology

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 48.

Tytuł:

Monitoring of plasma concentration of pyrimethamine (PYR) in infants with congenital Toxoplasma gondii infection – own observations
Monitorowanie stężenia pirymetaminy w surowicy krwi u niemowląt z wrodzonym zarażeniem Toxoplasma gondii – obserwacje własne

Autorzy:

Lipka, B.
Milewska-Bobula, B.
Filipek, M.

Powiązania:

https://bibliotekanauki.pl/articles/2143336.pdf

Data publikacji:

2011

Wydawca:

Polskie Towarzystwo Parazytologiczne

Tematy:

monitoring
plasma concentration
pyrimethamine
infant
Toxoplasma gondii
infection
congenital disease
treatment

Opis:

The study objective was to determine plasma concentration of pyrimethamine in 24 infants aged 1–5 months, treated for congenital toxoplasmosis. Pyrimethamine was used in a single daily dose at an amount of 0.35–0.98 mg/kg daily, with sulfadiazine (50–100 mg/kg/day) in divided doses 2–3 times a day, and folinic acid given twice a week (7.5 mg). This regimen was continued for 2–6 months, then Fansidar® was administered. Pyrimethamine concentration in plasma was measured using high-performance liquid chromatography method (HPLC). A total of 70 tests were performed. Concentration of pyrimethamine ranged from 0.01 to 1.2 μg/ml. In 14 children (58 tests) the concentration of pyrimethamine achieved therapeutic value. In 7 patients (8 tests) the concentration was below therapeutic level, and in 3 patients (4 tests) above therapeutic level. In 11/24 (46%) children transient moderate neutropenia was observed. Modification of therapy was necessary in 12 patients. Monitoring of pyrimethamine concentration in plasma improves safety and effectiveness of the therapy and is useful in obtaining correct individual dose of the drug. Neutropenia is the most common side-effect of pyrimethamine observed even when using the recommended dose.

Źródło:

Wiadomości Parazytologiczne; 2011, 57, 2; 87-92
0043-5163

Pojawia się w:

Wiadomości Parazytologiczne

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 49.

Tytuł:

Laryngological symptoms of gastroesophageal reflux disease

Autorzy:

Mierzwa, Grażyna
Sinkiewicz, Anna

Powiązania:

https://bibliotekanauki.pl/articles/1400277.pdf

Data publikacji:

2017

Wydawca:

Index Copernicus International

Tematy:

gastroesophageal reflux disease
laryngopharyngeal reflux
extraesophageal symptoms
proton pump inhibitors
treatment

Opis:

The artical presents a case of a 32 years old men with extraoesophagal symptoms of gastroesohagal reflux disease and laryngopharyngeal reflux. He was by ph-impedance monitoring, stroboskopy and gastrointestinal endoscopy with biopsy diagnosed. PPI therapy with dexlansoprasole was most efficient.

Źródło:

Polski Przegląd Otorynolaryngologiczny; 2017, 6, 2; 70-75
2084-5308
2300-7338

Pojawia się w:

Polski Przegląd Otorynolaryngologiczny

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 50.

Tytuł:

Ischaemic heart disease among workers in occupations associated with heavy lifting

Autorzy:

Hannerz, Harald
Holtermann, Andreas

Powiązania:

https://bibliotekanauki.pl/articles/2177445.pdf

Data publikacji:

2015-09-15

Wydawca:

Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi

Tematy:

occupational epidemiology
cohort studies
heavy lifting
cardiovascular disease
hospital treatment
Mortality

Opis:

Objectives To investigate a hypothesized positive association between employment in occupations where heavy lifting is likely to occur, and the risk of ischaemic heart disease (IHD). Material and Methods Male blue-collar workers from Denmark (N = 516 180) were monitored with respect to hospital treatment or death due to IHD, through national registers over the years 2001–2010. Poisson regression was used to estimate relative rates of IHD between “workers in occupations which, according to an expert opinion, are likely to involve heavy lifting” and “other blue-collar workers.” Prevalent cases were excluded from the analysis. Results The rate ratio was estimated at 0.97 (95% confidence interval (CI): 0.94–1.00) for deaths or hospitalizations due to IHD and 1.07 (95% CI: 0.94–1.21) for deaths due to IHD. Conclusions The results do not support the hypothesis that occupational heavy lifting is an important risk factor for IHD.

Źródło:

International Journal of Occupational Medicine and Environmental Health; 2016, 29, 1; 129-136
1232-1087
1896-494X

Pojawia się w:

International Journal of Occupational Medicine and Environmental Health

Dostawca treści:

Biblioteka Nauki

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