Skocz do pozycji: 1.

Tytuł:

Choroba przewlekła jako przeszkoda w osiąganiu niezależności u dzieci
Chronic disease as a barrier in achieving of independence by children

Autorzy:

Konieczna, Iwona

Powiązania:

https://bibliotekanauki.pl/articles/920320.pdf

Data publikacji:

2015-09-15

Wydawca:

Uniwersytet im. Adama Mickiewicza w Poznaniu

Tematy:

chronic disease
self – reliance
independence
child with chronic disease

Opis:

Chronic diseases determine children’s functioning in different areas of their life. It is caused very often by unclear experiences which are result of typical disease unit (such as physical pain, activity restriction), impact into environment (feeling of danger, fear, physical suffering).Very important seems to be here unit’s activity which play main role in coping process1. Because of many experiences child gain knowledge referring to concrete events strictly connected to therapy process. Basing on this child have a possibility to choose proven strategies which are foundation to effective coping with disease and give possibility to gain wellbeing, efficiency, independence which lead to effective development.

Źródło:

Interdyscyplinarne Konteksty Pedagogiki Specjalnej; 2015, 10; 181-197
2300-391X

Pojawia się w:

Interdyscyplinarne Konteksty Pedagogiki Specjalnej

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 2.

Tytuł:

Application of neuromuscular electrical stimulation of the lower limb skeletal muscles in the rehabilitation of patients with chronic heart failure and chronic obstructive pulmonary disease

Autorzy:

Kucio, Ewa
Niesporek, Justyna
Kucio, Cezary

Powiązania:

https://bibliotekanauki.pl/articles/551617.pdf

Data publikacji:

2017

Wydawca:

Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych

Tematy:

neuromuscular electrical stimulation
chronic heart failure
chronic obstructive pulmonary disease.

Źródło:

Family Medicine & Primary Care Review; 2017, 1; 71-74
1734-3402

Pojawia się w:

Family Medicine & Primary Care Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 3.

Tytuł:

Prevalence of Chronic Venous Disorders Among Employees Working in Prolonged Sitting and Standing Postures

Autorzy:

Sudoł-Szopińska, I.
Bogdan, A.
Szopiński, T.
Panorska, A. K.
Kołodziejczak, M.

Powiązania:

https://bibliotekanauki.pl/articles/89813.pdf

Data publikacji:

2011

Wydawca:

Centralny Instytut Ochrony Pracy

Tematy:

chronic venous disorders
occupational chronic venous insufficiency
duplex Doppler sonography

Opis:

Research was conducted to determine the prevalence and severity of chronic venous disorders (CVD) among people working in prolonged sitting or static standing postures. Clinical examination and duplex Doppler sonography were performed on 126 employees working in a sitting (96 individuals) or a standing posture (30 individuals). Evidence of CVD was found in 59.4% of individuals working in a sitting posture and in 83.4% of those working in a standing posture, and was significantly higher in employees working in a standing posture (p = .015). Incompetent perforating veins and vena saphena magna valves, and bilateral changes were the more frequent signs of CVD. The investigation showed that prolonged standing and sitting at work increases risk of developing CVD. Further, people working in a standing posture are at a significantly greater risk for CVD than those working in a prolonged sitting posture. They should thus be the subject of specific prophylaxis interventions.

Źródło:

International Journal of Occupational Safety and Ergonomics; 2011, 17, 2; 165-173
1080-3548

Pojawia się w:

International Journal of Occupational Safety and Ergonomics

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 4.

Tytuł:

Chronic rhinosinusitis in children

Autorzy:

Zielnik-Jurkiewicz, Beata

Powiązania:

https://bibliotekanauki.pl/articles/1400060.pdf

Data publikacji:

2017

Wydawca:

Index Copernicus International

Tematy:

rhinosinusitis
chronic
children
treatment

Opis:

CRS symptoms in children can be mild and uncharacteristic. The disease is multifactorial, and therefore requires a multifaceted, multidisciplinary approach. Treatment of CRS in children is difficult, infections often recur, and treatment methods are often ineffective. In children, surgery is performed infrequently, only when other therapies have failed. The first stage of surgery is adenoidectomy. Functional endoscopic surgery of the paranasal sinuses may be considered if no improvement of the patient after exhausting all possibilities of conservative treatment.

Źródło:

Polski Przegląd Otorynolaryngologiczny; 2017, 6, 1; 26-34
2084-5308
2300-7338

Pojawia się w:

Polski Przegląd Otorynolaryngologiczny

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 5.

Tytuł:

Usage of pregabalin in the treatment of pain associated with chronic pancreatitis – a clinically oriented narrative review

Autorzy:

Gałązka, Jakub K.
Skrzydło-Radomańska, Barbara
Kasztelan-Szczerbińska, Beata
Cichoż-Lach, Halina

Powiązania:

https://bibliotekanauki.pl/articles/24987725.pdf

Data publikacji:

2023-06-22

Wydawca:

Gdański Uniwersytet Medyczny

Tematy:

chronic pancreatitis
pain
pregabalin

Opis:

Abdominal pain is one of the main symptoms of pancreatic diseases, including chronic pancreatitis (CP). Once the disease is in remission, pain management is a key element of treatment. Co-analgesics may also be used at any stage of analgesia, among which antiepileptic drugs such as pregabalin. The first data on the beneficial effect of pregabalin on pain in the course of CP was published in a clinical trial in 2011, and it has been known since 2015 that the analgesic effect of pregabalin on CP has a different mechanism of action than conventional analgesics. Currently, research is focused on combining pregabalin with antioxidants and on methods to predict the patient's response to pregabalin administration. Based on current research, pregabalin appears to be a very useful agent for the pharmacologic treatment of pain in the setting of CP.

Źródło:

European Journal of Translational and Clinical Medicine; 2023, 6, 2; 91-94
2657-3148
2657-3156

Pojawia się w:

European Journal of Translational and Clinical Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 6.

Tytuł:

Osobowość jako wyznacznik przystosowania psychospołecznego i dobrostanu chorych przewlekle
Personality as the indicator of psychosocial adjustment and well-being of chronic patients

Autorzy:

Bajcar, Anita

Powiązania:

https://bibliotekanauki.pl/articles/468216.pdf

Data publikacji:

2012

Wydawca:

Uniwersytet Pedagogiczny im. Komisji Edukacji Narodowej w Krakowie

Tematy:

psychosocial adjustment
chronic disease
personality

Opis:

The purpose of the studies was to search for personality correlates of psychosocial adjustment of chronic disease patients. The group of 246 male patients with coronary heart disease was included into the studies. Correlations were analysed between the intensity of some selected personal traits, the intensity of limitations resulting from the disease process and its therapy, and the level of patients’ psychosocial adjustment and well-being. The studies have confirmed that the neuroticism, extraversion and openness are the essential correlates of the adjustment. In order to predict the psychosocial adjustment of chronic patients accurately, it is necessary to consider some variables connected with the disease. They can be the independent predicators of the adjustment, they can also modify the adjustment level when interacting with personality variables.

Źródło:

Annales Universitatis Paedagogicae Cracoviensis. Studia Psychologica; 2012, 5; 44-53
2084-5596

Pojawia się w:

Annales Universitatis Paedagogicae Cracoviensis. Studia Psychologica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 7.

Tytuł:

Skuteczność hiperbarii tlenowej w leczeniu ran przewlekłych
Effectiveness of oxygen hiperbaria in treating chronic wounds

Autorzy:

Mackiewicz, Barbara
Rezmerska, Leokadia

Powiązania:

https://bibliotekanauki.pl/articles/1029784.pdf

Data publikacji:

2017

Wydawca:

Państwowa Uczelnia Zawodowa we Włocławku

Tematy:

chronic wound
treatment
oxygen hiperbaria

Opis:

Introduction. Chronic wound it is a loss of skin caused by morbidity process or wound which, although treated stops at the stage of inflammation, and does not give any chance of both full re construction of tissues and undertaking physiological processes. The problem of chronic wounds is connected with the increase of civilization diseases. Trophic ulcerations of tibia caused by vessels’ atherosclerosis or unhealig wounds connected with the syndrome of diabetic foot make an interdisciplinary problem in medicine. Employing hyperbaric therapy compliment standard procedures in treating chronic wounds in accordance with TIME strategy as well as with treating serious illness. Aim. The aim of this research was the assessment of oxygen hiperbaria in chronic wounds treatment. Material and methods. 31 patients of the Oxygen Hiperbaria and Wounds Treatment Centre in Bydgoszcz took part in this research. The research was carried from November, 2016 until May, 2017. The patients were people aged 21-80 years old, both women and men. The method of diagnostic survey was used in the research. Questionnaire was the tool for the survey. Results. The results of the research were processed and then presented in tables and graphs along with their description. Conclusions. 1. The effectiveness of oxygen hiperbaria in treating chronic wounds does not depend on represented sex, age, education or marital status of the patients. 2. The effectiveness of oxygen hiperbaria in treating chronic wounds does not depend on patients’ physical activities. 3. The effectiveness of oxygen hiperbaria in treating chronic wounds does not depend on the amount of time which has passed since the beginning of the onset of chronic wound in case of treated patients.
Wstęp. Rana przewlekła to ubytek skóry powstający w wyniku procesu chorobowego czy urazu, który mimo leczenia zatrzymuje się na etapie stanu zapalnego i nie daje całkowitej odbudowy tkanek oraz podjęcia procesów fizjologicznych. Problem ran przewlekłych wiąże się ze wzrostem występowania chorób cywilizacyjnych. Owrzodzenia troficzne goleni czy z powodu miażdżycy naczyń lub niegojące się rany w zespole stopy cukrzycowej stanowią problem interdyscyplinarny w medycynie. Stosowanie terapii hiperbarycznej stanowi uzupełnienie standardowego postępowania w leczeniu ran przewlekłych, zgodnego ze strategią TIME i leczeniem choroby zasadniczej. Cel. Celem badań była ocena skuteczności hiperbarii tlenowej w leczeniu ran przewlekłych. Materiał i metody. Badaniami objęto 31 osób, które były pacjentami Centrum Hiperbarii Tlenowej i Leczenia Ran w Bydgoszczy. Badania wykonano w okresie od października 2016 roku do maja 2017 roku. Badanymi osobami byli pacjenci w wieku 21-80 lat, zarówno kobiety jak i mężczyźni. W badaniach wykorzystano metodę sondażu diagnostycznego. Techniką badań była ankieta. Narzędzie badawcze stanowił kwestionariusz ankiety własnej konstrukcji. Wyniki. Wyniki badań zostały poddane opracowaniu i analizie statystycznej, a następnie przedstawione graficznie w tabelach wraz z ich opisem. Wnioski. 1. Skuteczność hiperbarii tlenowej w leczeniu ran przewlekłych nie zależy od płci, wieku, wykształcenia i stanu cywilnego osób badanych. 2 Skuteczność hiperbarii tlenowej w leczeniu ran przewlekłych nie zależy od aktywności fizycznej osób badanych. 3. Skuteczność hiperbarii ia rany przewlekłej u osób badanych.

Źródło:

Innowacje w Pielęgniarstwie i Naukach o Zdrowiu; 2017, 2, 3; 11-27
2451-1846

Pojawia się w:

Innowacje w Pielęgniarstwie i Naukach o Zdrowiu

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 8.

Tytuł:

Iron deficiency in pregnant women suffering from chronic pyelonephritis

Autorzy:

Rozhkovska, NN
Sadovnichaya, OO.

Powiązania:

https://bibliotekanauki.pl/articles/1032515.pdf

Data publikacji:

2014

Wydawca:

Uniwersytet Kazimierza Wielkiego w Bydgoszczy

Tematy:

iron deficiency
chronic pyelonephritis
pregnancy

Opis:

The aim of the study was the assessment of the peculiarities of iron metabolism in pregnant women suffering from chronic pyelonephritis. There was shown that pregnant females have signs of iron deficiency anemia which is more severe in women suffering from chronic pyelonephritis. The iIncidence of chronic pyelonephritis in women with signs of syderopenic syndrome is 35.0 %. There is discussed the pathogenesis of iron deficiency related to the renal dysfunction.

Źródło:

Journal of Health Sciences; 2014, 4, 1; 145-150
1429-9623

Pojawia się w:

Journal of Health Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 9.

Tytuł:

New experimental model of chronic traumatic osteomyelitis for lower jaw

Autorzy:

Pohodenko-Chudakova, I. O.

Powiązania:

https://bibliotekanauki.pl/articles/285671.pdf

Data publikacji:

2008

Wydawca:

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów

Tematy:

osteomyelitis
chronic traumatic
lower jaw

Źródło:

Engineering of Biomaterials; 2008, 11, no. 77-80; 1-2
1429-7248

Pojawia się w:

Engineering of Biomaterials

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 10.

Tytuł:

Opposite changes of regulatory T cell blood content may differentially contribute to atherosclerosis or lymphoproliferative disorders

Autorzy:

Pylaeva, Ekaterina
Potekhina, Aleksandra
Pogorelova, Olga
Tripoten, Maria
Balakhonova, Tatiana
Filatova, Anastasia
Klesareva, Elena
Afanasieva, Olga
Noeva, Elena
Arefieva, Tatiana

Powiązania:

https://bibliotekanauki.pl/articles/1064986.pdf

Data publikacji:

2016

Wydawca:

Medical Education

Tematy:

B-cell chronic lymphocytic leukemia

Opis:

Background. Chronic autoimmune inflammation in arterial wall may lead to atherosclerosis progression. Objective. The aim of this study was to investigate the association between Treg, Th17 and B1a cell blood frequencies as well as IgM autoantibodies to oxLDL and the abundance of carotid atherosclerosis. Material and methods. 18 patients with increased IMT (intima-media thickness) and 65 patients with different severity of carotid atherosclerotic plaques were included. Treg, Th17 and B1a cell blood frequencies were assessed via direct immunofluorescence staining and flow cytometry, oxLDL as well as IgM autoantibodies to oxLDL were measured with commercial kits. Results. We observed higher values of Treg in patients without carotid atherosclerosis. Patients with intact carotid arteries as compared to patients with mild atherosclerotic plaques had decreased Th1 levels. OxLDL IgM levels were higher in patients with intact carotid arteries. Patients who received statin treatment had higher levels of Treg. Immunophenotyping of B cells revealed two cases of monoclonal B-cell lymphocytosis and 1 case of B-CLL (B-cell chronic lymphocytic leukemia) in elderly patients with intact carotid arteries. Conclusion. We hypothesize that certain parameters of cell immunity may hamper atherosclerosis while protecting from lymphoproliferative disorders.

Źródło:

OncoReview; 2016, 6, 1; A29-36
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 11.

Tytuł:

Parity does not affect diabetes complications in women with type 1 diabetes

Autorzy:

Cypryk, K.
Grycewicz, J.
Świerzewska, P.
Kosiński, M.
Lewiński, A.
Żurawska-Klis, M.

Powiązania:

https://bibliotekanauki.pl/articles/2081577.pdf

Data publikacji:

2018

Wydawca:

Instytut Medycyny Wsi

Tematy:

diabetes
obstetric history
chronic complications

Opis:

Introduction. The problem concerning the impact of pregnancy on diabetic complications is a matter for discussion as there is some evidence suggesting that pregnancy may trigger development or progression of diabetic chronic complications. However, currently available data concerning this issue is still controversial. Objective. The aim of the study was to evaluate the impact of obstetric history on the development of chronic microangiopatic and macroangiopatic complications in type 1 diabetic women. Materials and Method. The retrospective study comprised 226 white Caucasian type 1 diabetic women, including 190 parous and 36 nulliparous women. Anthropometric data, information concerning the course of the disease, including metabolic control and chronic complications, together with obstetric history, were registered. Results. Parous women were older (p<0.001), but did not differ significantly regarding metabolic control in the course of the disease (p>0.05) and diabetes duration (p>0.05) from nulliparous subjects. There were no significant differences in the incidence (p>0.05) nor onset (p>0.05) of chronic diabetes complications between the groups. The number of deliveries did not correlate with either the incidence nor the onset of chronic complications. Longer DM duration at the moment of first delivery was related to the higher incidence of retinopathy (p<0.01), nephropathy (p<0.05) and neuropathy (p<0.001). Conclusions. The incidence of chronic diabetic complications does not differ between parous women and the subjects that were never pregnant, and is not related to the number of pregnancies.

Źródło:

Annals of Agricultural and Environmental Medicine; 2018, 25, 1; 114-119
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 12.

Tytuł:

Dimensions of Temperament in Adults With Chronic Stuttering in the Light of I. P. Pavlov’s Theories

Autorzy:

Humeniuk, Ewa
Tarkowski, Zbigniew

Powiązania:

https://bibliotekanauki.pl/articles/31343318.pdf

Data publikacji:

2023

Wydawca:

Katolicki Uniwersytet Lubelski Jana Pawła II. Towarzystwo Naukowe KUL

Tematy:

temperament
Pavlov
chronic stuttering
adults

Opis:

The aim of the study was to determine dimensions of temperament in adults with chronic stuttering in the light of Pavlov’s temperament typology. The test sample consists of a (1) clinical group—adults with chronic stuttering (N = 202); and (2) a criterion group—adults with normal speech fluency (N = 198). The Pavlovian Temperament Survey (PTS) by Strelau and Zawadzki and our own survey were administered. Stutterers, compared to subjects with normal speech fluency, are characterized by a lower level of the excitation process, mobility and balance of nervous processes; they also tend to exhibit a higher level of the inhibition process. The severity of stuttering, the age at which the first symptoms of speech disfluency occur, treatment, evaluation of its effectiveness and intention to undergo therapy do not differentiate stutterers in terms of the considered temperament traits. The temperamental factors of chronic stuttering as per Pavlov’s typology are: increased reactivity to stimuli, reduced ability to adapt to new situations, the ability to flexibly respond to changing conditions, a weak type of the nervous system (lower strength of the excitation process, weaker mobility of the nervous processes), which makes it difficult to cope with challenges encountered and increases susceptibility to mental disorders.

Źródło:

Roczniki Psychologiczne; 2023, 26, 1; 5-21
1507-7888

Pojawia się w:

Roczniki Psychologiczne

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 13.

Tytuł:

Problemy pielęgnacyjne pacjenta z wielochorobowością w przebiegu otyłości
Nursing problems of the patient with multichorism in the treatment of obesity

Autorzy:

Żuchowska, Milena Małgorzata
Kochman, Dorota
Głowacka, Mariola

Powiązania:

https://bibliotekanauki.pl/articles/1029825.pdf

Data publikacji:

2017

Wydawca:

Państwowa Uczelnia Zawodowa we Włocławku

Tematy:

obesity
chronic diseases
self-care

Opis:

Excess body weight is considered to be a chronic disease, which is one of the greatest life and health risks. Obesity has a negative impact on the body, and the people affected by it are exposed to the development of serious diseases including diabetes, coronary artery disease, hypertension and brain strokes, gall bladder disease, certain types of cancer as well as to numerous psychosocial problems. Givining up obesity treatment might lead even to death. Obese people need multidirectional interdisciplinary therapeutic team in which a nurse is actively involved. The paper presents an individual case study and a care plan for a 46-year-old patient with obesity and numerous co-morbidities.
Nadmierna masa ciała uznana jest za chorobę przewlekłą, która stanowi jedno z największych zagrożeń życia i zdrowia. Otyłość ma negatywny wpływ na organizm, a ludzie, których ona dotyczy narażeni są na rozwój groźnych schorzeń takich jak: cukrzyca, choroba wieńcowa, nadciśnienie tętnicze i udary mózgu, choroby pęcherzyka żółciowego, niektóre rodzaje raka oraz liczne problemy psychospołeczne. Odstąpienie od leczenia otyłości prowadzi nawet do śmierci. Ludzie otyli potrzebują wielokierunkowych działań interdyscyplinarnego zespołu terapeutycznego, w których aktywnie uczestniczy pielęgniarka. W pracy przedstawiono opis indywidualnego przypadku i plan opieki wobec 46- letniego pacjenta z otyłością i wieloma chorobami współistniejącymi.

Źródło:

Innowacje w Pielęgniarstwie i Naukach o Zdrowiu; 2017, 2, 1; 87-111
2451-1846

Pojawia się w:

Innowacje w Pielęgniarstwie i Naukach o Zdrowiu

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 14.

Tytuł:

Physical activity as prevention of chronic illnesses in seniors

Autorzy:

Sygit, Katarzyna
Sygit, Marian
Pietrzak, Mariusz

Powiązania:

https://bibliotekanauki.pl/articles/1055006.pdf

Data publikacji:

2016

Wydawca:

Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego

Tematy:

chronic illnesses
physical activity
seniors

Opis:

Physical activity is of key importance in prevention of chronic illnesses, such as cardiovascular disease or metabolic diseases. Lack of regular workout in seniors favors the development of these diseases. It is, therefore, advisable to change one’s lifestyle and engage in regular workout in order to reduce the risk of chronic illnesses and disabilities. The aim of this paper is to present how important physical activity is in prevention of chronic illnesses in seniors.

Źródło:

Central European Journal of Sport Sciences and Medicine; 2016, 14, 2; 79-86
2300-9705
2353-2807

Pojawia się w:

Central European Journal of Sport Sciences and Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 15.

Tytuł:

Kategorie zdrowia, choroby w kontekście niepełnosprawności – ujęcie teoretyczne
Categories of health and disease in the context of disability – theoretical framework

Autorzy:

Antoszewska, Beata
Bartnikowska, Urszula

Powiązania:

https://bibliotekanauki.pl/articles/930449.pdf

Data publikacji:

2018-01-30

Wydawca:

Uniwersytet im. Adama Mickiewicza w Poznaniu

Tematy:

health
disease
chronic disease
disability

Opis:

Life is of great value to any human being and can be considered to be a fundamental concept. It has a determined temporal dimension, although it remains unknown to a given individual. An overview of relevant literature demonstrates that much has been written on the subject of health and ability and it has been quite extensively discussed. Yet this concept remains valid because its meaning is constantly changing. People are not able to completely free themselves from diseases/disabilities. During one’s lifetime one is exposed to periodic or permanent difficulties or limitations. Human life involves functioning on the border of health and disease, full ability and disability. It is important, however, how one deals with difficulties that one must face, who one will meet on one’s way and what kind of help will be offered. This paper aims to present a theoretical framework of health and disease, including chronic disease and disability.

Źródło:

Interdyscyplinarne Konteksty Pedagogiki Specjalnej; 2016, 13; 67-86
2300-391X

Pojawia się w:

Interdyscyplinarne Konteksty Pedagogiki Specjalnej

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 16.

Tytuł:

Comparison of single-layer continues or two-layer interrupted pancreatojejunal suture in Frey procedure for treatment of chronic pancreatitis: a prospective randomized study

Autorzy:

Šileikis, Audrius
Jurevičius, Saulius
Butvila, Mykolas
Strupas, Kęstutis

Powiązania:

https://bibliotekanauki.pl/articles/1392105.pdf

Data publikacji:

2019

Wydawca:

Index Copernicus International

Tematy:

chronic pancreatitis
Frey procedure
pancreatojejunostomy

Opis:

Background: Many patients with chronic pancreatitis are elected for surgery when endoscopic interventions are ineffective. Duodenum preserving pancreatic head resection introduced by Charles F. Frey is the most common procedure used for surgical treatment of chronic pancreatitis. However, technical aspects of this procedure have not been studied extensively. Goal Our prospective randomized study is aimed to compare usage of single-layer continuous (I group) and two-layer interrupted sutures (II group) in constructing pancreatojejunostomy after Frey procedure. Methods and materials: In a period between 2009 and 2016, a total of 103 patients, diagnosed with chronic pancreatitis and determined medical indications for surgical treatment were included into the study and randomized into group I (52 patients) and group II (51 patients). Preoperative, intraoperative patient characteristics and postoperative results were compared between both groups. Results: Mean duration of surgery was statistically shorter in group I – 210 min, while in group II – 240 min (p = 0.004). Pancreatojejunoanastomosis construction time was shorter in group I – 19 (±6) min versus 51 (±18) min in group II, p <0,001. No statistically relevant differences were observed in postoperative morbidity: group I – 51.9% and group II – 45,1% (p = 0.177) and mortality: group I – 3.8% and group II – 2% (p = 0.636). Conclusions: Frey procedure using single-layer continuous pancreatojejunostomy is safe, fast and less complex method in surgical treatment of chronic pancreatitis.

Źródło:

Polish Journal of Surgery; 2019, 91, 6; 11-14
0032-373X
2299-2847

Pojawia się w:

Polish Journal of Surgery

Dostawca treści:

Biblioteka Nauki

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Tytuł:

HSP70 (HSPA1) polymorphisms in former workers with chronic mercury vapor exposure

Autorzy:

Chernyak, Yury I.
Merinova, Alla P.

Powiązania:

https://bibliotekanauki.pl/articles/2161928.pdf

Data publikacji:

2017-02-21

Wydawca:

Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi

Tematy:

chronic mercury vapor exposure
chronic mercury intoxication
heat shock protein 70
HSPA1 polymorphisms
genetics in occupational health
association with chronic mercury intoxication

Opis:

Objectives To investigate 4 loci of 3 HSP70 genes in caustic soda production plant former workers, who have been exposed to metallic mercury vapors for a long time, and including numerous cases of chronic mercury intoxication (CMI). Material and Methods Polymorphisms in HSP70 gene family members (HSP1A1 (+190G/C, rs1043618), HSPA1B (+1267A/G and +2074G/C, rs1061581) and HSP1AL (+2437T/C, rs2227956)) genes were studied among 120 male workers involved in caustic soda production by mercury electrolysis at 2 plants in Eastern Siberia. These subjects had been chronically exposed to metallic mercury vapors for > 5 years and divided into 3 groups based on the occurrence and time of the CMI diagnosis, or absence of this disease. The Group 1 consisted of individuals (N = 46), who had had contact with mercury but were not diagnosed with the CMI. The Group 2 included workers (N = 56), who were diagnosed with the CMI longer than 14 years ago. The Group 3 consisted of the subjects (N = 18), who had been diagnosed with the CMI 3–5 years ago. The logistic regression analysis was used for 3 genetic models with and without adjustment for age and duration of mercury vapor exposure. Results We found that genotypes СС-HSPA1A (+190G/C) and GG-HSPA1B (+1267A/G) had a high predictive risk of the CMI development (adjusted odds ratio ($\text{OR}_\text{adj}$) = 5.58, p = 0.026 and $\text{OR}_\text{adj}$ = 14.7, p = 0.0015, respectively). Twelve individuals with the CMI had a specific combination of СС-HSPA1A (+190G/C) and GG-HSPA1B (+1267A/G) genotypes, which strongly associated with the diagnosis ($\text{OR}_\text{adj}$ = 12.3, p = 0.0285). Moreover, significant association with the CMI was also obtained for the haplotype G-C of 1267A/G and 190G/C polymorphisms (OR = 2.1, p = 0.018). Conclusions The association of СС-HSPA1A (+190G/C) and GG-HSPA1B (+1267A/G) genotypes and their combination for the CMI individuals suggests the role for HSPA1 genes in mercury-dependent mechanisms of the CMI development and progression. Int J Occup Med Environ Health 2017;30(1):77–85

Źródło:

International Journal of Occupational Medicine and Environmental Health; 2017, 30, 1; 77-85
1232-1087
1896-494X

Pojawia się w:

International Journal of Occupational Medicine and Environmental Health

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 18.

Tytuł:

What does post-exercise proteinuria tell us about kidneys?

Autorzy:

Wołyniec, Wojciech
Ratkowski, Wojciech
Zorena, Katarzyna
Januszczyk, Jacek
Kuźbicka, Karolina
Urbański, Robert
Tkachenko-Rita, Patrycja
Renke, Marcin
Rachoń, Dominik

Powiązania:

https://bibliotekanauki.pl/articles/1054979.pdf

Data publikacji:

2016

Wydawca:

Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego

Tematy:

albuminuria
chronic kidney disease
health
running

Opis:

Objectives. Post exercise proteinuria (PEP) is found in about 20–40% of sportsmen after intensive exercise. Urinary NGAL is a new marker of tubulointerstitial kidney damage. The relationship between PEP and uNGAL has not been defined yet. In presented study a resting uNGAL as a predictor of PEP was analyzed. The changes of albuminuria after exercise were monitored to estimate a frequency and range of PEP. Methods. 40 amateur healthy runners (mean age 36.65 ±10.61 years) participating in 10-km run took part in the study. Before and after the competition urine was collected. NGAL, albumin and creatinine were subsequently measured in urine. uNGAL to creatinine ratio (NCR) and albumin to creatinine ratio (ACR) were calculated. Results. 28 participants (mean age 37.9 ±11.46, 19 M, 9 F) with uNGAL below 15 ng/ml before competition were analyzed. The increase of ACR was observed in every case. Mean post-exercise ACR was 104.55 ±123.1 mg/g and was significantly higher than pre-exercise ACR 6.33 ±5.86 mg/g (p < 0.0005). The positive correlation was found between resting NCR and post-exercise ACR (r = 0.60, p < 0.05). Conclusions. Resting uNGAL positively correlated with PEP. The possible explanation of these findings is that persons with PEP had some early, occult tubulointersitial kidney damage. It is speculated that those runners have higher risk of chronic kidney disease.

Źródło:

Central European Journal of Sport Sciences and Medicine; 2016, 14, 2; 93 - 100
2300-9705
2353-2807

Pojawia się w:

Central European Journal of Sport Sciences and Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 19.

Tytuł:

Frequency Dependent Incidence Model for Acute and Chronic Schistosomiasis

Autorzy:

Derick, Ngobi
Onuorah, Martins O.

Powiązania:

https://bibliotekanauki.pl/articles/1077429.pdf

Data publikacji:

2019

Wydawca:

Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN

Tematy:

Schistosomiasis
acute
chronic
endemic
equilibrium
stability

Opis:

In this research work, a deterministic mathematical model for schistosomiasis transmission dynamics is presented. The model consists of five non-liniar ordinary differential equations incorporating the acute and chronic infectious compartments. The basic reproductive number, (the number of secondary infections when a single infectious individual is introduced into a population where everyone is susceptible) was obtained. Furthermore, we gained and analyzed for stability, the disease-free and endemic equilibrium. The qualitative feature of the model shows that the long-term behavior of the model is independent of initial conditions. Numerical simulation of the various state variables were obtained using matlab software.

Źródło:

World News of Natural Sciences; 2019, 23; 276-296
2543-5426

Pojawia się w:

World News of Natural Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Tytuł:

Aliskiren - an antihypertensive renin inhibitor in the treatment of patients with chronic kidney disease

Autorzy:

Łukawski, Krzysztof
Baranowicz-Gąszczyk, Iwona

Powiązania:

https://bibliotekanauki.pl/articles/972635.pdf

Data publikacji:

2017

Wydawca:

Instytut Medycyny Wsi

Tematy:

aliskiren
chronic kidney disease
clinical studies

Opis:

Introduction. The renin-angiotensin-aldosterone system (RAAS) plays an important role in the pathogenesis of hypertension, cardiovascular diseases (CVDs) and chronic kidney disease (CKD). Drugs affecting the RAAS system, such as angiotensinconverting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs), are commonly used in the treatment of hypertension and heart failure. These drugs are also effective in reducing proteinuria and may, at least, delay end-stage renal disease in both diabetic and non-diabetic proteinuric CKD. However, novel drugs are needed to more effectively suppress the RAAS system and the progression of CKD. Aliskiren is the first direct renin inhibitor which has been approved for the treatment of hypertension. Additionally, a number of clinical studies have shown the antiproteinuric effect of aliskiren. Objective. This review focuses on the antihypertensive and antiproteinuric effects of aliskiren in patients with CKD. The pharmacology of aliskiren in these patients is also provided. Conclusions. Aliskiren-based hard endpoint large trials in non-diabetic nephropathy are needed in order to clarify the use of aliskiren in CKD patients.

Źródło:

Journal of Pre-Clinical and Clinical Research; 2017, 11, 1; 81-85
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

/5

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Tytuł:

Zapalenie brzegów powiek – wszechstronne spojrzenie na powszechne schorzenie
Blepharitis: a comprehensive look at a common disease

Autorzy:

Karaszewski, Michał
Misiuk-Hojło, Marta
Przeździecka-Dołyk, Joanna
Gnus, Jan

Powiązania:

https://bibliotekanauki.pl/articles/1927528.pdf

Data publikacji:

2020

Wydawca:

Medical Education

Tematy:

Meibomian gland dysfunction
chronic blepharitis
demodex

Opis:

Zapalenie brzegów powiek to rozpowszechniona na całym świecie, częsta, przewlekła choroba zapalna aparatu ochronnego oczu, której szczegółowa epidemiologia jest trudna do ustalenia. Również rola poszczególnych czynników etiologicznych, takich jak kolonizacja nużeńcem, pozostaje niedookreślona. Rozpoznanie opiera się na wszechstronnym badaniu przedmiotowym w połączeniu z dokładnym badaniem okulistycznym, uzupełnionym o ewentualne badania dodatkowe. Terapia jest długotrwała i zwykle nie prowadzi do pełnego wyleczenia, wymaga od pacjentów cierpliwości i systematycznego zaangażowania. Stale poszerzany wachlarz terapeutyczny pozostaje poza refundacją w ramach publicznej opieki zdrowotnej większości krajów.
Chronic blepharitis is a common, chronic inflammatory disease of the external eye whose detailed epidemiology is difficult to determine. Also, the role of individual etiological factors, such as demodex infestation, remains undefined. The diagnosis is based on a comprehensive physical examination with a thorough ophthalmological examination, supplemented with possible additional examinations. The therapy lasts long and usually does not lead to full recovery, requires patience and systematic commitment from patients. The constantly expanding therapeutic range is not reimbursed by public healthcare in most countries.

Źródło:

OphthaTherapy; 2020, 7, 3; 192-202
2353-7175
2543-9987

Pojawia się w:

OphthaTherapy

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 22.

Tytuł:

Bacterial biofilm and its relation to cervical adenopathy, tonsillar hypertrophy and adenoid hypertrophy in chronic tonsillitis

Autorzy:

Eid, Mustafa I
Elabd, Safia H
Erfan, Dina M
Ziada, Kholood W
Ezzat, Abdelrahman E. M

Powiązania:

https://bibliotekanauki.pl/articles/1401686.pdf

Data publikacji:

2016

Wydawca:

Index Copernicus International

Tematy:

bacterial biofilm
chronic tonsillitis
antibiotic resistance

Opis:

Background: Bacterial biofilms have been linked to recurrent adenotonsillar diseases, with special concern regarding therapeutic management hindered by antibiotic resistance. Aims: we aimed to find if there was a relationship between the presence of a bacterial biofilm and the development of cervical lymphadenopthy, tonsillar hypertrophy and adenoid hypertrophy in patients with chronic tonsillitis. Patients and Methods: Tissue samples from tonsillar biopsies of 30 children who underwent tonsillectomy were examined by scanning electron microscopy (SEM). Settings and Design: This cross-sectional study was conducted between August 2012 and July 2015 in Al-Azhar University Hospitals. Results: It was found that 23.3% of children had a fully formed bacterial biofilm (Grade III), 6.7% had grade I and 6.7% had grade II biofilms as demonstrated by SEM. Staphylococcus aureus was the most common identified isolate (26%) followed by Coagulase-negative Staphylococci (17.4%) and Klebsiella pneumoniae (10.4%). No statistically significant difference regarding the presence of a bacterial biofilm and the development of cervical lymphadenopthy, tonsillar hypertrophy or adenoid hypertrophy was found. Conclusion: Bacterial biofilm is a possible cause of the chronicity of tonsillar diseases in children. There is no relationship between the presence of a bacterial biofilm and the development of of cervical lymphadenopthy, tonsillar hypertrophy or adenoid hypertrophy.

Źródło:

Polski Przegląd Otorynolaryngologiczny; 2016, 5, 3; 28-32
2084-5308
2300-7338

Pojawia się w:

Polski Przegląd Otorynolaryngologiczny

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 23.

Tytuł:

The effect of preserved stapedial superstructure on hearing improvement

Autorzy:

Boroń, Aleksandra
Wiatr, Agnieszka
Składzień, Jacek
Wiatr, Maciej

Powiązania:

https://bibliotekanauki.pl/articles/1397296.pdf

Data publikacji:

2020

Wydawca:

Index Copernicus International

Tematy:

chronic otitis media
stapedial superstructure
tympanoplasty

Opis:

Introduction: Ossiculoplasty can be carried out in a number of ways, depending on the anatomical and functional conditions encountered during otosurgery and the experience of a given centre. The extent of damage to the ossicular chain determines the reconstruction method. Aim: The objective of the study was to analyse treatment effects in terms of postoperative hearing improvement in patients with chronic otitis media, with a particular emphasis on stapedial superstructure preservation. Material and method: The records of 294 consecutive patients undergoing their first ENT surgery due to chronic otitis media at the Department of Otolaryngology of Collegium Medicum, Jagiellonian University of Kraków in 2009–2013 were analysed. In order to assess the role of preserved stapedial superstructure, 96 patients were eligible for further analysis. Results: The analysis points to a significant hearing improvement after ossiculoplasty with the preserved stapedial superstructure as compared with the patients after footplate mobilisation. On the other hand, the research results point to significantly smaller hearing improvement in those patients, in whom only stapes was preserved, as compared with those, in whom a more extensive reconstruction of the ossicular chain was possible. Conclusions: The air-bone gap measured before otosurgery often fails to reflect the extent of abnormalities and cannot, therefore, be considered as the only prognostic factor for postoperative hearing improvement. Stapes preservation is crucial for hearing improvement after middle ear surgery.

Źródło:

Polish Journal of Otolaryngology; 2020, 74, 1; 17-22
0030-6657
2300-8423

Pojawia się w:

Polish Journal of Otolaryngology

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 24.

Tytuł:

AUTOPERCEPCJA U DZIECI Z CHOROBĄ PRZEWLEKŁĄ
SELF – PERCEPTION OF CHILDREN WITH CHRONIC DISEASE

Autorzy:

Konieczna, Iwona

Powiązania:

https://bibliotekanauki.pl/articles/549964.pdf

Data publikacji:

2016

Wydawca:

Uniwersytet Kardynała Stefana Wyszyńskiego w Warszawie

Tematy:

autopercepcja
choroba przewlekła
dziecko z chorobą przewlekłą
self–perception
chronic disease
child with chronic disease

Opis:

W artykule zostanie podjęta próba syntezy wiedzy teoretycznej oraz uogólnionych rezultatów doniesień empirycznych na temat postrzegania siebie przez dzieci z chorobami przewlekłymi. Należy podkreślić, że proces poznawania siebie, swoich możliwości, ale także ograniczeń w różnych obszarach życia jest długotrwały, niezwykle złożony i wieloczynnikowy, szczególnie jeśli chodzi o dzieci, i musi uwzględniać specyfikę poszczególnych jednostek chorobowych.
This paper attempts to synthesize the theoretical knowledge and generalize the empirical results regarding self – perception in children with chronic disease. It should be emphasized that the process of self – perception and own possibilities and restrictions in different areas of life is very complicated, long lasting and multifactorial, especially in children, taking into consideration the characteristics of particular disease entities.

Źródło:

Forum Pedagogiczne; 2016, 1; 233-246
2083-6325

Pojawia się w:

Forum Pedagogiczne

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 25.

Tytuł:

Oral cavity status of long-term hemodialized patients vs. their socio-economic status

Autorzy:

Trzcionka, Agata
Twardawa, Henryk
Mocny-Pachońska, Katarzyna
Tanasiewicz, Marta

Powiązania:

https://bibliotekanauki.pl/articles/2085564.pdf

Data publikacji:

2020-05-15

Wydawca:

Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi

Tematy:

chronic diseases
socio-economic status
end-stage chronic kidney disease
oral health
hemodialysis
health maintenance

Opis:

BackgroundThe chronic kidney disease, blood hypertension and diabetes are recognized as civilization diseases that affect more and more people. The probability of encountering a patient suffering from these diseases is increasing. As such, it appears crucial to better understand the specific dental needs of such groups of patients. The aim of the work was to assess the oral hygiene status and the needs of patients suffering from the end-stage chronic kidney disease, arterial hypertension or/and diabetes.Material and MethodsTwo hundred and twenty eight patients were included in the research. One hundred and eighty patients were hemodialized in Diaverum dialysis stations and 48 patients were from the Conservative Dentistry with Endodontics Clinic of the Academic Centre of Dentistry in Bytom, Silesian Medical University in Katowice, and from the Dentistry Division of the Arnika Clinic in Zabrze, and were not not diagnosed with any of the diseases mentioned. The research scheme was divided into 3 parts, consisting of an analysis of the general health socio-economic status, a survey and an assessment of oral health.ResultsThe patients who were not suffering from any of the discussed diseases were more aware of how to properly perform hygienic procedures. Most of the patients from both the control and examined groups were not using any rinsing solutions. A higher percentage of patients in the control group was using dental floss, changing their toothbrush every 3 months and brushing their teeth for ≥2 min. The Aproximal Plaque Index and the Oral Hygiene Index-Simplified values in the control group were significantly lower in comparison to the examined group.ConclusionsThe socio-economic status of hemodialized patients was low, which in most cases was a result of the difficulties in starting a job. Due to the lower standards of life, the neglect of oral hygiene maintenance and its consequences could be observed.

Źródło:

Medycyna Pracy; 2020, 71, 3; 279-288
0465-5893
2353-1339

Pojawia się w:

Medycyna Pracy

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 26.

Tytuł:

The Struggle with Time in Chronic Illness

Autorzy:

Ostrowska, Antonina

Powiązania:

https://bibliotekanauki.pl/articles/1929489.pdf

Data publikacji:

2008-04-03

Wydawca:

Polskie Towarzystwo Socjologiczne

Tematy:

time
chronic disease
trajectory
dialysis
transplantation

Opis:

It is worth looking at chronic illness with its pain, suffering and increasing limitations from the perspective of time. By time we mean subjective time relating to the perception and dynamics of the malady in the patient’s impressions and the role which time plays in the structuring of the patient’s life and experience. The main focus of this article is the experience of progressive kidney failure (uraemia), a condition which requires regular dialysis or kidney transplantation. Due to its specific crises, hopes and periods of waiting, painstaking medical procedures lasting many hours and turning points in the disease’s trajectory, time and its passage are a particularly adequate instrument with which to analyse the experiences of patients with uraemia. These experiences are discussed against the backdrop of selected elements of health care and attitudes towards transplantation which provide the social context for patients’ struggle with illness.

Źródło:

Polish Sociological Review; 2008, 161, 1; 25-38
1231-1413
2657-4276

Pojawia się w:

Polish Sociological Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 27.

Tytuł:

Serum cytokines and activation ex vivo of CD4plus and CD8plus T cells in chagasic chronic Mexican patients

Autorzy:

Cruz-Robles, David
Vargas-Alarcón, Gilberto
Ortíz-Muñiz, Rocio
Reyes, Pedro A.
Monteon, Victor M.

Powiązania:

https://bibliotekanauki.pl/articles/972123.pdf

Data publikacji:

2017

Wydawca:

Polskie Towarzystwo Parazytologiczne

Tematy:

Chagas discase
cytokines
chronic chagasic cardiomyopathy

Opis:

The clinical manifestations of human Chagas disease are associated with several factors, including immunological alterations, in this regard, many studies propose that tissue damage might be more severe in the absence of immune regulatory mechanisms, other factors are the genetic background of host and parasite. Trypanosoma cruzi population is genetically, biochemistry and pathogenic diverse along the Latin-America continent and phylogenetic ally are divided into six intra-species lineages TcI-VI. The TcI lineage has a wide distribution with heterogeneous virulence and pathogenesis within strains. In Mexico, the main circulating lineage is TcI in human infections. We analyzed intracytoplasmic cytokines of unstimulated peripheral T lymphocytes, and the level of cytokines (IL-2, IL-4, IL-12, IL-10, IFN-γ and sIL-2R) in the serum of Mexican chagasic subjects. The population studied consisted of 15 asymptomatic individuals, 17 patients with chronic chagasic cardiopathy (CCC), 20 patients with cardiopathy but negative serology for T. cruzi, and 10 healthy subjects. The analysis of CD4+ cells revealed that CCC and asymptomatic patients have higher CD25+ and CD69 activation markers than controls. The Th1 subset (CD4+/IFN- γ +) was higher in CCC than in asymptomatic and control subjects, whereas Th2 subset was markedly high in asymptomatic subjects. Circulating cytokines were below level detection with the exception of IL-2 and sIL-2R. Infection with Mexican Trypanosoma cruzi strains in asymptomatic chagasic subjects have a tendency for a Th2 response with higher CD8+/IFN-γ T cells. In contrast, CCC patients have low levels of intracellular IFN- γ and IL-2 cytokines. In both groups circulating serum cytokines are below the detectable level.

Źródło:

Annals of Parasitology; 2017, 63, 4; 299-308
0043-5163

Pojawia się w:

Annals of Parasitology

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 28.

Tytuł:

Evaluation of the quality of life of patients with osteoarthritis

Autorzy:

Niczyporuk, M.
Kłossowska, J.
Kleszczewska, E.
Shpakou, A.
Knaś, M.

Powiązania:

https://bibliotekanauki.pl/articles/1918782.pdf

Data publikacji:

2018

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

uality of life
osteoarthritis
chronic diseas

Opis:

Purpose: The tools for measuring objective quality of life include research regarding the conditions of a successful life and life satisfaction. Osteoarthritis (OA) is characterized by progressive degradation and loss of articular cartilage as well as abnormal bone growth and remodeling, located directly under the cartilage. The aim of this study is to answer the question on which level OA patients perceive their quality of life dependent on health. Material and methods: The Polish version of the HAQ questionnaire, assessing the quality of life over the past week, was used for overall assessment of quality of life. The Polish version of the AIMS-2 questionnaire was used as a specific questionnaire for assessing the health status of patients with osteoarthritis. Surveys were conducted in a group of 240 people. Results: The quality of life dependent on health is significantly reduced in the group of healthy people who take painkillers sporadically because of other reasons and in the OA pateints group compared to the control group, the same as in the OA pateints group compared to the group of healthy people who take painkillers sporadically for other reasons. Conclusions: According to the answers from the questionnaire, patients with OA seek different forms of improving their quality of life. It is important to change their lifestyle (weight reduction, using a bench-mounted bike, walking stick or walking frame), reducing the surface area of the joints, reducing the defective position of the limb axis. Exercises that increase muscle mass and exercises to improve joint mobility should be introduced. It is advisable to refer the OA patient for physical therapy and/or balneotherapy.

Źródło:

Progress in Health Sciences; 2018, 8(2); 1-9
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 29.

Tytuł:

Ocena stanu zdrowia dzieci wrocławskich w wieku 6,5–9,5 lat. Część 2
The health status of Wrocław’s children from 6.5 to 9.5 years of age. Part 2

Autorzy:

Noczyńska, Anna
Zubkiewicz-Kucharska, Agnieszka
Mysłek-Prucnal, Monika
Bosak-Prus, Magdalena

Powiązania:

https://bibliotekanauki.pl/articles/552596.pdf

Data publikacji:

2014

Wydawca:

Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych

Tematy:

allergy
malformation
chronic disease
posture defect

Opis:

Wstęp. Obserwowany na świecie wzrost zachorowania na choroby cywilizacyjne dotyczy w dużym stopniu również dzieci. Cel pracy. Ocena sytuacji zdrowotnej dzieci uczęszczających do trzech pierwszych klas szkół podstawowych we Wrocławiu. Materiał i metody. Badaniem objęto 1984 dzieci (97,92%) – 934 chłopców (47%) i 1050 dziewczynek (53%), w wieku 6,5–9,5 lat z 26 wybranych losowo publicznych szkół we Wrocławiu. Badania przeprowadzano w latach 2009–2011. Rozdano 4000 ankiet, w których pytano rodziców o przebyte i aktualne choroby oraz wady rozwojowe. Wyniki. Zespoły genetycznie uwarunkowane były rozpoznane u 15 (0,75%), wady układu moczowego – u 24 (1,2%), serca – u 9 (0,45%), przewodu pokarmowego – u 24 (1,2%), wady wzroku – u 236 (11,8%), choroby alergiczne – u 597 (30,1%), astma oskrzelowa – u 33 (1,51%) badanych. Z powodu chorób endokrynologicznych leczonych jest 15 (0,75%) dzieci. U 66/934 (7,06%) chłopców rozpoznano wady układu moczopłciowego. U 402 (20,2%) dzieci rozpoznano wadę postawy,z czego u 20 (1%) wady były utrwalone. Wnioski. Opieka pediatryczna w szkołach jest niezadowalająca. Najważniejszymi problemami zdrowotnymi u dzieci klas I–III są choroby alergiczne oraz wady postawy, na co wpływ mogą mieć czynniki środowiskowe. W celu poprawy stanu zdrowia dzieci konieczna jest edukacja prozdrowotna dzieci, a szczególnie rodziców
Background. Increase in civilization diseases prevalence has also been noticeable in children worldwide. Objectives. The aim of this study was to assess the health situation of Wroclaw’s children during the first three years of school education. Material and methods. The study included 1984 children (97.92%), 934 boys (47%) and 1050 girls (53%), who were attending 26 randomly selected public schools in Wrocław. The study was conducted in 2009–2011. 4000 questionnaires on past and current chronic diseases as well as developmental disturbances were given to legal guardians of children taking part in the project. Results. Genetic disorders and syndromes were present in 15 (0.75%) children, malformations of urinary system in 24 (1.2%), heart defects in 9 (0.45%), digestive system disease in 24 (1.2%), vision defects in 236 (11.8%), allergy in 597 (30.1%) and asthma in 33 (1.51%) participants. 15 (0.75%) children were treated due to endocrinological diseases. In 66/934 (7.06%) boys genital organs malformations were diagnosed. Stature defect was diagnosed in 402 (20.2%) examined, including 20 (1%) with fixed defects. Conclusions. Pediatric care provided in school is unsatisfactory. Allergy and stature defects dominated among all found disorders that could result from environmental factors. Effective education of healthy lifestyle should help to improve health status of school children.

Źródło:

Family Medicine & Primary Care Review; 2014, 1; 29-31
1734-3402

Pojawia się w:

Family Medicine & Primary Care Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 30.

Tytuł:

Tissue remodelling in chronic rhinosinusitis – review of literature

Autorzy:

Radajewski, Kamil
Wierzchowska, Małgorzata
Grzanka, Dariusz
Antosik, Paulina
Zdrenka, Marek
Burduk, Paweł

Powiązania:

https://bibliotekanauki.pl/articles/1397806.pdf

Data publikacji:

2019

Wydawca:

Index Copernicus International

Tematy:

chronic rhinosinusitis
nasal polyps
tissue remodeling

Opis:

CRS is a process involving a number of adverse changes in the mucosa of the paranasal sinuses and nasal polyps, e.g. increased fibroblast proliferation, angiogenesis, increased formation of fibrous tissue (subepithelial fibrosis) and tissue destruction. There are biomarkers whose levels can be increased in chronic inflammation of the paranasal sinuses: peripheral blood eosinophilia, IgE immunoglobulin, cytokines – IL-4, IL-5, IL-13, IL-25, IL-33, periostin, P-glycoprotein, CXCL-12, CXCL-13, INF-Υ, TNFα, TGFβ1, albumins, eotaxin. These biomarkers are not pathognomonic for CRS. The concentration of biomarkers is also increased in bronchial asthma and atopic dermatitis. The TGFβ, in particular the β1 subunit, was identified as the main factor involved in the remodelling of tissue stroma. In conjunction with continuous improvement of tissue testing methods, it is advisable to search for new factors that will more accurately allow the assessment of tissue remodelling in the chronic processes of paranasal sinuses.

Źródło:

Polish Journal of Otolaryngology; 2019, 73, 5; 1-4
0030-6657
2300-8423

Pojawia się w:

Polish Journal of Otolaryngology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 31.

Tytuł:

Factors that have an influence on bone conduction thresholds changes after otosurgery in the patients operated on due to the perforation of the tympanic membrane with the preserved ossicular chain

Autorzy:

Wiatr, Maciej
Wiatr, Agnieszka
Kocoń, Sebastian
Składzień, Jacek

Powiązania:

https://bibliotekanauki.pl/articles/1398515.pdf

Data publikacji:

2017

Wydawca:

Index Copernicus International

Tematy:

bone conduction
miryngoplasty
chronic otitis media

Opis:

Introduction: The aim of the middle ear surgery is to eliminate abnormalities from the mucous, ensure the due airing of the postoperative cavity and reconstruct the sound-conducting system in the middle ear. Numerous reports can be found in literature on the changes to bone conduction as a consequence of middle ear surgery. Study objective: The aim of the work is to define the factors that affect bone conduction in the patients operated on due to the perforation of the tympanic membrane with the preserved and normal mobile ossicular chain. Material and method: A prospective analysis of patients operated on due to diseases of the middle ear in 2009–2012 was carried out. The cases of patients operated on for the first time due to chronic otitis media were taken into consideration. The analysis encompassed the patients who had undergone myringoplasty. The patients were divided into several groups taking into account the abnormalities of the mucous observed during otosurgery. Results: A significant improvement of bone conduction was observed in the patients with dry perforation, without other lesions in the middle ear. The appropriate pharmacological treatment before otosurgery in patients with permanent discharge from the ear resulted in significant bone conduction improvement. The elimination of granulation lesions turned out to be a positive factor for the future improvement of the function of the inner ear. Conclusions: The lack of abnormalities on the mucous of the middle ear (e.g. granulation,) and discharge has a positive impact on improvement of bone conduction after myringoplasty. Adhesions in the tympanic cavity, especially in the niche of the round window, have a negative impact on improvement of bone conduction in patients after myringoplasty.

Źródło:

Polish Journal of Otolaryngology; 2017, 71, 4; 26-33
0030-6657
2300-8423

Pojawia się w:

Polish Journal of Otolaryngology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 32.

Tytuł:

Depression symptoms, anxiety and personality traits in patients with coronary artery disease versus patients with chronic pancreatitis hospitalised due to exacerbation of the disease

Autorzy:

Szalewska, Dominika
Szidlewska, Małgorzata
Skoczkowska-Niedoszytko, Marta
Amr Elkady, Mohamed

Powiązania:

https://bibliotekanauki.pl/articles/552441.pdf

Data publikacji:

2016

Wydawca:

Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych

Tematy:

depression
chronic pancreatitis
anxiety
coronary artery disease

Źródło:

Family Medicine & Primary Care Review; 2016, 4; 477-481
1734-3402

Pojawia się w:

Family Medicine & Primary Care Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 33.

Tytuł:

Management of a traumatic hip dislocation in a young chronic paraplegic patient. Enigma and program

Autorzy:

Ohry, Avi

Powiązania:

https://bibliotekanauki.pl/articles/1033830.pdf

Data publikacji:

2015

Wydawca:

Zakład Opieki Zdrowotnej Ośrodek Umea Shinoda-Kuracejo

Tematy:

chronic paraplegia
traumatic hip dislocation
rehabilitation medicine

Opis:

The rare occurrence of hip dislocation in a chronic young paraplegic person evoked many clinical questions: the possible etiologies and differential diagnoses of this situation, the possible and feasible treatments, and the prevention of probable further complications.

Źródło:

Medicina Internacia Revuo; 2015, 26, 104; 143-145
0465-5435

Pojawia się w:

Medicina Internacia Revuo

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 34.

Tytuł:

The use of over-the-counter analgesics in patients with chronic kidney disease

Autorzy:

Jakimowicz-Tylicka, Marzena
Chmielewski, Michał
Kuźmiuk-Glembin, Izabella
Skonieczny, Piotr
Dijakiewicz, Grażyna
Zdrojewska, Grażyna
Rutkowski, Bolesław
Tylicki, Leszek
Dębska-Ślizień, Alicja

Powiązania:

https://bibliotekanauki.pl/articles/895741.pdf

Data publikacji:

2019-02-05

Wydawca:

Gdański Uniwersytet Medyczny

Tematy:

chronic kidney disease
analgesics
over-the-counter

Opis:

Background: Analgesics can be sold following medical prescription, but also as over-the-counter (OTC) medications. In patients with chronic kidney disease (CKD), their use could potentially be associated with increased risk of side-effects, due to impaired renal elimination. The aim was to evaluate the epidemiology and indications for the use of OTC analgesics, and the knowledge of their side-effects in patients with CKD. Material and methods: A cross-sectional, controlled survey on the use of OTC analgesic drugs was conducted among 180 CKD patients (stage 1-5, dialysis, kidney transplant), compared to 60 controls. Results: The proportion of patients using OTC analgesics on a regular basis was higher in the CKD group, compared to controls (18.9% vs. 10.0%, p<0.02). The major indications included musculoskeletal issues, followed by headaches and other. Subgroup analysis revealed that analgesic use was lowest among transplanted patients, in comparison to CKD stage 1-5, and dialysis subjects (10%, 20%, 26%, respectively, p=0.06). Less than half of CKD patients and controls declared any knowledge on potential side-effects of analgesic drugs (45.6% vs. 40.0%, NS). Conclusions: The use of OTC analgesics among patients with CKD is higher than in subjects without CKD, with the exception of transplanted patients. The knowledge on the potential side-effect of analgesics is limited.

Źródło:

European Journal of Translational and Clinical Medicine; 2018, 1, 2; 11-16
2657-3148
2657-3156

Pojawia się w:

European Journal of Translational and Clinical Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 35.

Tytuł:

Myeloid sarcoma associated with blast crisis in chronic myelogenous leukemia - case report

Autorzy:

Szymczyk, Agnieszka
Podhorecka, Monika
Tomczak, Waldemar
Szumiło, Justyna
Hus, Marek

Powiązania:

https://bibliotekanauki.pl/articles/972387.pdf

Data publikacji:

2016

Wydawca:

Instytut Medycyny Wsi

Tematy:

myeloid sarcoma
chronic myelogenous leukemia
blast crisis

Opis:

Introduction. Myeloid sarcoma (MS) is a rare extramedullary tumour which may precede or occur concomitantly with bone marrow involvement in acute myeloid leukemia, myelodysplastic syndrome, or blast crisis in chronic myeloproliferative disorder. Myeloid sarcoma is most commonly found in lymph nodes, skin, subcutaneous tissue and gums, while it is less common in bones, the retroperitoneal space and eye socket. Case Report. The case is reported of a 65-year-old woman with chronic myelogenous leukemia treated for about 20 years with hydroxyurea, 6-mercaptopurine and tyrosine-kinase inhibitors. During the treatment, the general condition of the patient progressively deteriorated, lymphadenopathy and splenomegaly worsened, and blast crisis was diagnosed. After the first cycle of induction chemotherapy, the patient’s lymph nodes were swollen and painful. One of the lymph nodes was subjected to histopathology, on the basis of which a diagnosis of MS was made. As the patient showed no response to the treatment, palliative care was initiated. Three months after the diagnosis of MS, the disease progressed. The patient died of infectious complications. Conclusions: A diagnosis of MS, which is considered an adverse prognostic factor, significantly reduces the chances of remission and overall survival in patients with acute myelogenous leukemia or blast crisis inchronic myeloproliferative disorders. It seems that early confirmation of the diagnosis and initiation of the treatment adjusted to the patient’s clinical condition may improve the prognosis and increase the response rates.

Źródło:

Journal of Pre-Clinical and Clinical Research; 2016, 10, 2; 136-139
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 36.

Tytuł:

Chronıc dısease rısks of workers in a factory and theır tendency to practıce preventıve health behavıours

Autorzy:

Tugba, K.E.
Ilknur, A.A.

Powiązania:

https://bibliotekanauki.pl/articles/1917828.pdf

Data publikacji:

2016

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

Chronic disease
hazelnut workers
preventive health behaviors

Opis:

Aim: This study has been conducted to detect chronic disease risk of nut-factory workers and to identify their tendency to practice preventive health behaviours. Materials and methods: Study universe is composed of 104 workers working at a hazelnut factory in Ordu, Turkey. Indicative characteristics survey form which is composed of 29 questions and prepared by the researcher, Multidimensional Health Locus of Control Scale B Form and Perception of Health Status Scale were used. In statistical evaluation fo data, percentage evaluation, arithmetic average, t-test, single factor analysis, ANOVA test were used. Results: According to data obtained from the study, it was found that most of the participants are overweight and obese, and are hypertension patients. Score average of workers was good according to perception of health scale status was better. It was found that there is a statistical relation between gender, educational status, chronic disease status, preventive health behaivors, cancer screening status, tension, fasting blood glucose and body mass index and Multidimensional Health Locus of Control Scale scores (p<0.01, p<0.05). It was determined that there is a statistical relation between gender, educational status, chronic disease status, preventive health disease and tension measurement values of laborers and their Perception of Health Status Scale scores [p<0.01] [p<0.05]. Conclusion: This study shows that workers have risk in the sense of chronic diseases. Results attained and training to be carried out have great importance for early diagnosis, information and application and development of preventive health behaviors of chronic diseases of workers by the workplace nurse

Źródło:

Progress in Health Sciences; 2016, 6(2); 29-38
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 37.

Tytuł:

The frequency of chronic diseases and a health-promoting lifestyle in a group of elderly Romani people living in Northern Turkey

Autorzy:

Aydın, M.
Aydın-Avci, İ.

Powiązania:

https://bibliotekanauki.pl/articles/1918776.pdf

Data publikacji:

2018

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

Chronic disease
elderly age
healthy lifestyle
Romani

Opis:

Purpose: To analyse the frequency of chronic diseases among Romani people who are sixty and older as well as their health-promoting lifestyle. Materials and methods: This research was conducted as a descriptive study between January 2015 and June 2015. The study included 98 elderly Romani people lived in Samsun, Turkey. The study data were collected using the questionnaire included 22 questions along with the Health-promoting Lifestyle Scale II. The statistical analysis of the data was made using percentage means, t-test, correlation, and ANOVA test. Results: The average age of the participating Romani people was 66.7±5.3. Of these Romani people, 83.7% had a chronic disease, and 80.6% had a medication that they used regularly. The mean score of the Romani citizens in the study sample on the Health-promoting Lifestyle Scale was 115.98±15.82. They obtained their highest score on the inter-personal relations sub-dimension and the lowest score on the stress management sub-dimension of the scale. There was a statistical correlation between the Romani people's gender, social insurance, income level, education level, family type, body mass index (BMI) and blood pressure monitoring and their scores on the scale (p<0.05). The study found that a health-promoting lifestyle did not affect the frequency of chronic diseases (p˃0.05). Conclusions: This study proved that the Romani people had risks of chronic diseases, did not attach sufficient importance to a health-promoting lifestyle and their health-promoting lifestyle is weaker compared to the elders in the rest of the population.

Źródło:

Progress in Health Sciences; 2018, 8(2); 75-84
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 38.

Tytuł:

Are three months multidisciplinary lifestyle intervention enough to get benefits on blood pressure in overweight/obese adults ?

Autorzy:

Pippi, Roberto
Bini, Vittorio
Reginato, Elisa
Aiello, Cristina
Fanelli, Carmine

Powiązania:

https://bibliotekanauki.pl/articles/1925583.pdf

Data publikacji:

2021-03-17

Wydawca:

PPHU Projack Jacek Wąsik

Tematy:

Exercise
Lifestyle
Obesity
Blood Pressure
Chronic disease

Opis:

The aim of the study is to determine the effects of a multidisciplinary lifestyle intervention (including a short period of physical exercise) on some health-related variables, particularly on blood pressure, in an overweight/obese adult group. The main outcome was blood pressure lowering. The study involved 378 subjects affected by obesity or type 2 diabetes. The intervention included exercise, nutrition and psychological aspects. Before and after the intervention, several anthropometrics, cardiovascular risk related measures (height, body weight, body mass index, waist circumference, body composition and WHTR index) and physical exercise measures (aerobic capacity, flexibility and dynamic muscle strength) were evaluated through fitness tests. We observed a significant reduction in: blood pressure values, body weight, BMI, waist circumference, WHTR, fat mass and an improvement of fat free mass and physical exercise measures. The C.U.R.I.A.Mo. multidisciplinary approach is effective for reducing blood pressure, after relatively few exercise sessions (three weeks), particularly in patients with hypertension. The intervention can ameliorate the health status and physical performance in the short term, in normotensive and hypertensive adult subjects with overweight/obesity.

Źródło:

Physical Activity Review; 2021, 1, 9; 40-53
2300-5076

Pojawia się w:

Physical Activity Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 39.

Tytuł:

The impact of treatment under subterraneotherapy conditions at the “Wieliczka” Salt Mine Health Resort on the symptoms of diseases of the nose and paranasal sinuses

Autorzy:

Woźniak, Aleksandra
Nowak, Karol
Pełkowska, Anna
Rys, Katarzyna
Gawlik, Jolanta
Składzień, Jacek

Powiązania:

https://bibliotekanauki.pl/articles/1398963.pdf

Data publikacji:

2021

Wydawca:

Index Copernicus International

Tematy:

chronic non-allergic rhinitis
respiratory rehabilitation
subterraneotherapy

Opis:

Introduction: Chronic rhinosinusitis is an important disease of the upper respiratory system which substantially reduces patient quality of life and the methods of symptomatic treatment are tremendously limited. Aim: The aim of this study was to evaluate the next therapeutic option which is a combination of respiratory rehabilitation and subterraneotherapy. Material and methods: The study covered 57 patients of whom 15 were men and 42 women. The average age of patients was 60 +/- 10.87 (standard deviation). 44 patients finished 15 days of therapy which covers full-time treatment. The average age of these patients was 59.7 +/- 11.6 (standard deviation). Results: In the study group, there was a statistically significant reduction among all analyzed symptoms of chronic rhinosinusitis. The general severity of symptoms decreased from 5.66 cm to 2.57 cm (p < 0.001), blockade/congestion of the nose from 5.49 to 2.23 cm (p < 0.001), anterior nasal discharge from 5.33 cm to 2.5 cm (p < 0.001), posterior nasal discharge from 6.04 cm to 2.71 cm (p < 0.001), facial pain/pressure from 3.43 cm to 1.45 cm (p < 0.001), headache from 3.73 cm to 1.19 cm (p < 0.001) and reduction or loss of smell from 4.17 cm to 1.94 cm (p < 0.001). Conclusions: Such a notable improvement in all analyzed symptoms led us to conclude that respiratory rehabilitation, especially such conducted in adequate climatic conditions, should be a valuable therapeutic option in the symptomatic treatment of patients with chronic rhinosinusitis.

Źródło:

Polski Przegląd Otorynolaryngologiczny; 2021, 10, 1; 22-27
2084-5308
2300-7338

Pojawia się w:

Polski Przegląd Otorynolaryngologiczny

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 40.

Tytuł:

Does smog affect the incidence of exacerbations of chronic laryngitis? Analysis based on the inhabitants of Lesser Poland Voivodeship.

Autorzy:

Ziarno, Remigiusz
Suska, Anna
Kulinowski, Wojciech
Grudzień-Ziarno, Aleksandra
Kostrzon, Magdalena
Paciorek, Magdalena
Składzień, Jacek

Powiązania:

https://bibliotekanauki.pl/articles/1398544.pdf

Data publikacji:

2017

Wydawca:

Index Copernicus International

Tematy:

air pollution
chronic laryngitis
phoniatrics
laryngography
subterraneotherapy

Opis:

Introduction: Due to dynamic industrialisation smog became a frequent phenomenon in most developing cities. According to the last WHO report from Global Urban Ambient Air Pollution Database, Krakow has been classified in the 11th place among the most polluted cities in Europe. It seems to be an urgent issue because of the influence of air pollution on the condition of upper respiratory tract. Materials & Methods: In December 2015 there were 141 patients aged 17-91 years with upper respiratory tract diseases admitted to the phoniatric outpatient clinic in the University Hospital in Cracow. They suffered from cough, hoarseness and periodic aphonia. On the basis of the results of videolaryngostroboscopy 60 patients with exacerbation of the chronic laryngitis were selected into two numerically equal groups: from Cracow and from other places at least 60 km away. The groups were equal to each other also in three categories: sex, age and voice usage. The patients were referred to the Pedagogical University in Cracow for laryngography to evaluate the movement of the vocal folds and to trace a voice profile. Finally, there were two possible types of treatment – conventional pharmacotherapy or subterraneotherapy in the underground Health Resort in the "Wieliczka" Salt Mine. Results: Pearson correlation coefficient between the distance from the place of residence to Cracow and the scale of exacerbation of inflammation of upper respiratory tract presenting as vocal fold dysfunction was observed (r= 0,617; p<0,05). Conclusion: The place of residence (in or out of the industrial area) and exacerbations of chronic laryngitis are highly correlated. Air pollution seems to be the main factor influencing on the condition of upper respiratory tract. In our local conditions of Lesser Poland Voivodeship subterraneotherapy may be an interesting, non-invasive method preventing from exacerbations of upper respiratory tract diseases.

Źródło:

Polish Journal of Otolaryngology; 2017, 71, 3; 10-19
0030-6657
2300-8423

Pojawia się w:

Polish Journal of Otolaryngology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 41.

Tytuł:

Importance of behavioral changes in identification of chronic pain and its causes in dogs – case report
Znaczenie zmian behawioralnych w identyfikacji bólu przewlekłego i jego przyczyn u psów – opis przypadku

Autorzy:

Karpiński, M.
Alchimowicz, K.
Wojtaś, J.
Łojszczyk, A.
Garbiec, A.

Powiązania:

https://bibliotekanauki.pl/articles/3131488.pdf

Data publikacji:

2021

Wydawca:

Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie

Tematy:

dog
chronic pain
identification
behavioural change
diagnostics

Źródło:

Acta Scientiarum Polonorum. Zootechnica; 2021, 20, 1; 55-60
1644-0714

Pojawia się w:

Acta Scientiarum Polonorum. Zootechnica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 42.

Tytuł:

Zespół wypalenia zawodowego w pracy pielęgniarki
The professional burnout in nursing

Autorzy:

Sodomska, Agata
Lomper, Katarzyna
Rycombel, Anna
Uchmanowicz, Izabella

Powiązania:

https://bibliotekanauki.pl/articles/470157.pdf

Data publikacji:

2014

Wydawca:

Europejskie Centrum Kształcenia Podyplomowego

Tematy:

wypalenie zawodowe
stres chroniczny
burnout
stress chronic

Opis:

Wstęp. Nieodzownym następstwem długotrwałego stresu jest wystąpienie syndromu wypalenia zawodowego. Wypalenie jest procesem, który rozwija się powoli. Pierwsze sygnały nie są dostrzegalne lub też są błędnie interpretowane. Szczególną grupą ryzyka narażoną na wypalenie są przedstawiciele zawodów pracujących dla ludzi i z ludźmi, a więc m.in. nauczyciele, policjanci, lekarze i pielęgniarki. Personel medyczny jest szczególnie narażony na wystąpienie syndromu wypalenia zawodowego, gdyż niejednokrotnie mimo ogromnego zaangażowania w pracę pacjent przegrywa w walce o zdrowie i życie. Cel pracy. Zbadanie poziomu wypalenia zawodowego wśród pielęgniarek/ pielęgniarzy. Materiał i metody. W badaniu wzięło udział 82 respondentów (80 kobiet i 2 mężczyzn). Badanie dotyczyło pielęgniarek/pielęgniarzy zatrudnionych w NZOZ Szpitala Powiatowego w Wieruszowie i zostało przeprowadzone w roku 2012. Do badania wykorzystano ankietę własnego autorstwa, która składała się z 22 pytań. Pytania ankiety zostały pogrupowane tematycznie: pierwsze cztery miały na celu zbadanie poziomu zmęczenia pracą, kolejnych pięć miało sprawdzić występowanie symptomów wypalenia zawodowego. Następne zagadnienia ankiety zdiagnozowały reakcję na stres chroniczny, empatię wobec pacjentów oraz stopień pozytywnego postrzegania pracy. Wyniki. Jednoznacznie o występowaniu wypalenia zawodowego mówi aż 40% pielęgniarek ze średnim stażem zatrudnienia, nieco mniej, bo 35% najmłodszych respondentów, również przyznaje, że mimo niezbyt długiego okresu pracy symptomy wypalenia są już u nich dostrzegalne. Natomiast najdłużej pracujące w zawodzie (tylko w 33%) mówią o wypaleniu zawodowym. Wnioski. Wypalenie zawodowe dosięga głównie pielęgniarki ze stażem pracy od 10 do 19 lat. Najlepiej zaprezentowały się pielęgniarki z najdłuższym stażem pracy. Zasadniczy wpływ na postawę, zaangażowanie i wystąpienie symptomów wypalenia zawodowego ma poczucie skuteczności i wrażenie, że w pracy nie osiągnęło się znaczących rezultatów.
Background. An essential consequence of prolonged stress is an instance of burnout syndrome. Burn-out is a process that develops slowly. The first signs are not visible or are misinterpreted. Special risk group exposed to burn are professionals working for and with people, and so teachers, police officers, doctors and nurses. Medical staff is particularly exposed to the instance of the burnout syndrome, because more often than not, despite a huge involvement in the work of the patient loss in the fight for health and life. Objectives. To examine the level of burnout among nurses. Material and methods. The study involved 82 respondents (80 women and 2 men). The study included nurses working in Hospital in Wieruszów it was carried out in 2012. We used a questionnaire that was developed by authors of this study, which consisted 22 questions. The survey questions have been grouped thematically, and so the first four questions were designed to examine the fatigue level of work, the following five questions were supposed to check the occurrence of symptoms of burnout. Another poll issues diagnosed the chronic stress, empathy to patients and the degree of positive perception of the work. Results. The occurrence of burnout was confirmed by 40% of nurses with the average length of employment, slightly less because 35% of the youngest respondents also confirm the burnout. Only 33% of nurses who are working for a long time in the profession confirm the professional burnout. Conclusions. Burnout reaches mainly nurses with experience lasting from 10 to 19 years. Impact on the attitude, commitment and an instance of the symptoms of burnout has a sense of efficacy and the impression that the work did not get significant results.

Źródło:

Współczesne Pielęgniarstwo i Ochrona Zdrowia; 2014, 2; 29-33
2084-4212

Pojawia się w:

Współczesne Pielęgniarstwo i Ochrona Zdrowia

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 43.

Tytuł:

Assessment of the efficacy of ofatumumab in patients with chronic lymphocytic leukaemia treated in the Department of Haematooncology and Bone Marrow Transplantation of the Medical University in Lublin - prelimary results

Autorzy:

Wasik-Szczepanek, E.
Szymczyk, A.
Kowal, M.
Nogalski, A.
Hus, M.

Powiązania:

https://bibliotekanauki.pl/articles/2081565.pdf

Data publikacji:

2018

Wydawca:

Instytut Medycyny Wsi

Tematy:

chronic lymphocytic leukemia
ofatumumab
monoclonal antibodies
immunotherapy

Opis:

Introduction. Despite significant recent advances in the treatment of chronic lymphocytic leukaemia (CLL), most cases of the disease are still incurable. Treatment with monoclonal antibodies, such as ofatumumab, is one of the new therapeutic options. Objective. Retrospective analysis of the efficacy of ofatumumab in patients with chronic lymphocytic leukaemia (CLL) treated in the Haematooncology and Bone Marrow Transplantation Department of the Medical University of Lublin, Poland, during 2011–2013. Materials and method. The analysis included 5 patients (3 women and 2 men), aged 47–65, with Rai stage II-IV CLL, after a few lines of treatment. Three patients received ofatumumab in monotherapy and 2 patients received ofatumumab in combination with cyclophosphamide (50 mg/day) and dexamethasone (40 mg/day). All patients included in the study were diagnosed with an active form of leukaemia with symptoms such as lymphocytosis or massive lymphadenopathy. Results. All patients responded to the treatment. Within the first 8 weeks of the treatment, levels of white blood cells returned to normal in patients with baseline lymphocytosis (3 patients). An increase in platelet levels was reported in 3 patients. Haemoglobin levels were higher or comparable to the baseline values in all studied patients after the completion of immunotherapy. In the patient with massive lymphadenopathy and hepato- and splenomegaly, the size of the lymph nodes, spleen and liver decreased and neutrophil levels increased. Time of progression was 5–12 months, and in one patient partial remission has been maintained. The treatment was well-tolerated in most cases. Asymptomatic neutropenia and an infection with Candida glabrata were observed. Conclusions. Ofatumumab may be a new and safe therapeutic option for patients with CLL after a few lines of treatment.

Źródło:

Annals of Agricultural and Environmental Medicine; 2018, 25, 1; 56-59
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 44.

Tytuł:

AN EVALUATION OF TRANSCRANIAL DIRECT CURRENT STIMULATION (TDCS) IN THE REDUCTION OF OCCUPATIONAL BURNOUT SYNDROME IN NURSES

Autorzy:

Wilczek-Rużyczka, Ewa
Gawrońska, Aleksandra
Góral-Półrola, Jolanta

Powiązania:

https://bibliotekanauki.pl/articles/2138033.pdf

Data publikacji:

2021-03-20

Wydawca:

Fundacja Edukacji Medycznej, Promocji Zdrowia, Sztuki i Kultury Ars Medica

Tematy:

neurotherapy
depression
chronic psychophysical exhaustion
vegetative problems

Opis:

The aim of the study was to answer the question as to whether transcranial direct current stimulation (tDCS) is more effective in reducing burnout syndrome in nurses than the commonly used individual psychotherapy. The study included 40 nurses from various health care facilities located in the Lesser Poland and Podkarpackie Voivodeship suffering from burnout syndrome. They were assigned to the experimental group while 20 to the control group. Two different therapy models were used: the experimental group (A) included 20 of the nurses treated with the use of transcranial direct current stimulation (tDCS), four times a week for 8 weeks, in sessions that lasted initially 10, then 15, 20, 25 and finally 30 minutes and the control group (B) included 20 of the nurses treated with individual psychotherapy employed for 8 weeks, once a week for 30 minutes. To evaluate the results we used: screening with a clinical interview, the Mini–Mental State Examination (MMSE), the Beck Depression Inventory and a Polish adaptation of the Italian questionnaire created by Massimo Sentinello (LBQ). Treatment was provided. The transcranial direct current stimulation (tDCS) used in Group A is more effective in reducing many symptoms than is the case with individual psychotherapy. Comparing the intragroup effects, it was found that the tDCS employed in Group A significantly reduced the intensity of depressive symptoms among the surveyed nurses [F (1.38) = 57.62; p <0.001; η2 = 0.603] while the individual psychotherapy used in Group B failed to produce a statistically significant effect [F (1.38) = 1.794; p = 0.188; η2 = 0.045]. These include a reduction of depression, a reduction in chronic psychophysical exhaustion, vegetative problem reduction, and the improvement of nurse-patient relations. Neurotherapy with the use of transcranial direct current stimulation (tDCS) is more effective in reducing burnout syndrome than the commonly used individual psychotherapy. It also helps to return these nurses to full professional activity. The studies presented above recommend the use of new neurotechnologies in therapy as a result of their usefulness and non-invasive character.

Źródło:

Acta Neuropsychologica; 2021, 19(2); 169-185
1730-7503
2084-4298

Pojawia się w:

Acta Neuropsychologica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 45.

Tytuł:

Predictors of hospitalization in patients presenting to emergency department with an acute exacerbation of COPD – a single-center study in Turkey

Autorzy:

Sanalp Menekşe, Tuğba
Taha Sert, Ekrem

Powiązania:

https://bibliotekanauki.pl/articles/29519429.pdf

Data publikacji:

2023-09-30

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

chronic obstructive pulmonary disease
emergency department
hospitalization

Opis:

Introduction and aim. In this study, we evaluated parameters that might be associated with hospitalization in patients admitted to the emergency department (ED) with an acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Material and methods. Patients with COPD who presented to ED due to AECOPD between January 1, 2020 and December 31, 2021 were included in the study. Patient data were obtained from the hospital database. Univariable and multivariable logistic regression methods were used to identify the relationship between hospitalization and clinical parameters. Results. The study included 237 patients divided into two groups: inpatients (n=124) and outpatients (n=113). We found significant differences between the two groups in terms of temperature, oxygen saturation, respiratory rate, C-reactive protein, white blood cell count, procalcitonin, albumin, arterial blood pH, pCO2, and non-invasive mechanical ventilation (NIMV) requirement. Multivariable logistic regression analysis showed that body temperature [odds ratio (OR):1.62;95% confidence interval (CI):1.21–4.91; p<0.001], oxygen saturation (OR:0.73, 95% CI:0.39-0.94, p<0.001), respiratory rate (OR:1.96; 95% CI: 1.07–6.14; p<0.001), albumin (OR:0.71; 95% CI:0.41–0.93; p=0.042), procalcitonin (OR:2.93; 95% CI:1.22–4.84; p<0.001), arterial blood pH (OR:0.78; 95% CI:0.29-0.91; p=0.038), pCO2 (OR:2.45; 95% CI:1.24–4.65; p<0.001), and NIMV requirement (OR:2.31; 95% CI:1.41–5.13; p<0.001) were the independent predictors of hospitalization. Conclusion. Our findings may help identify patients who will require hospitalization at an early stage.

Źródło:

European Journal of Clinical and Experimental Medicine; 2023, 3; 561-566
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 46.

Tytuł:

A Single-Blind Randomized Controlled Trial Investigating Changes in Electrical Muscle Activity, Pain, and Function after Shockwave Therapy in Chronic Non-Specific Low Back Pain: Pilot Study

Autorzy:

Elgendy, Mohamed Hussein
Mohamed, Mai
Hussein, Hisham Mohamed

Powiązania:

https://bibliotekanauki.pl/articles/28409172.pdf

Data publikacji:

2022-04-14

Wydawca:

Fundacja Edukacji Medycznej, Promocji Zdrowia, Sztuki i Kultury Ars Medica

Tematy:

chronic pain
electromyography
muscle
extracorporeal shockwave therapy

Opis:

Background. To investigate the effect of adding r-ESWT to a standard exercise program of chronic non-specific LBP on electrical muscle activity (EMG), pain and function. Materials and methods. Our single-blind randomized controlled trial enrolled 30 patients with chronic non-specific LBP randomly allocated to an r-ESWT (n=15) group and a control group (n=15). All patients received a standard exercise program, while r-ESWT was additionally administered in the r-ESWT group. EMG activity, pain and function were assessed before and after 6 weeks of treatment. Results. After treatment, all outcome measures were significantly different (p < 0.05). The addition of r-ESWT produced a significant increase in EMG activity (of all muscles tested) and a reduction in pain intensity and functional disability scores (p < 0.05) compared to the control group. Conclusions. 1. A standard intervention offered either alone or with r-ESWT increased EMG activities, reduced pain, and enhanced function in patients with chronic non-specific LBP. 2. Adding r-ESWT to the standard intervention program might produce better results.

Źródło:

Ortopedia Traumatologia Rehabilitacja; 2022, 24(2); 87-94
1509-3492
2084-4336

Pojawia się w:

Ortopedia Traumatologia Rehabilitacja

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 47.

Tytuł:

Children and adolescents with a chronic condition in the public school space – in search of an effective model of psychopedagogical support

Autorzy:

Krauze-Sikorska, Hanna

Powiązania:

https://bibliotekanauki.pl/articles/940918.pdf

Data publikacji:

2019-12-15

Wydawca:

Uniwersytet im. Adama Mickiewicza w Poznaniu

Tematy:

chronic condition
psychosocial issues of students with a chronic condition
model of supporting children and adolescents with a chronic condition in the educational and social space of the school

Opis:

Chronic condition may, in time, become a specific kind of „stigma” that determines the formation of a specific “conveyor belt” which determines the trajectories of the fate of children and adolescents. Analysing the functioning of children and adolescents with a chronic condition, for which the school should provide (as for other students) the conditions of learning, both in the cognitive and in the directional aspects, one may indicate not only the imperfections of educational activities, but also a myth of noble ideas inscribed in the function of school, as a place of universal development of every student. The article is a proposal of employing, within the process of educating children and adolescents with a chronic condition, an eclectic model of activities, based on their complexity and sequentiality. The model refers to models proposed by Frederick C. Thorne, or Richard James, used in situations of crisis intervention: the equilibrium model, the cognitive model, and the social change model.

Źródło:

Interdyscyplinarne Konteksty Pedagogiki Specjalnej; 2019, 26; 295-318
2300-391X

Pojawia się w:

Interdyscyplinarne Konteksty Pedagogiki Specjalnej

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 48.

Tytuł:

Clinical study on the application of dexamethasone and cyclosporine/dimethyl sulfoxide combination eye drops in the initial therapy of chronic superficial keratitis in dogs

Autorzy:

Balicki, I.
Szadkowski, M.
Balicka, A.
Zwolska, J.

Powiązania:

https://bibliotekanauki.pl/articles/2087091.pdf

Data publikacji:

2021

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

chronic superficial keratitis
German Shepherd
cyclosporine
DMSO

Źródło:

Polish Journal of Veterinary Sciences; 2021, 24, 3; 415-423
1505-1773

Pojawia się w:

Polish Journal of Veterinary Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 49.

Tytuł:

Serum paraoxonase 1 activity and lipid metabolism parameter changes in Dachshunds with chronic mitral valve disease.Assessment of its diagnostic usefulness

Autorzy:

Kulka, M.
Garncarz, M.
Parzeniecka-Jaworska, M.
Kluciński, W.

Powiązania:

https://bibliotekanauki.pl/articles/2087879.pdf

Data publikacji:

2017

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

PON1
chronic mitral valve disease
Dachshunds

Źródło:

Polish Journal of Veterinary Sciences; 2017, 4; 723-729
1505-1773

Pojawia się w:

Polish Journal of Veterinary Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 50.

Tytuł:

Anaemia in chronic kidney disease- new treatment options

Autorzy:

Żórawski, M.
Musiałowska, B.
Rudzińska, M.
Koc-Żórawska, E.
Małyszko, J.S.

Powiązania:

https://bibliotekanauki.pl/articles/1918763.pdf

Data publikacji:

2018

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

chronic kidney disease
anaemia
erythropoietin
hepcidin
iron

Opis:

In recent years anaemia has been recognized as one of the most specific and evident manifestations of chronic renal failure. In the majority of cases, renal anaemia is normocytic and normochromic with normal cellularity of bone marrow. Multiple factors contribute to the molecular origins of the anaemia of chronic kidney disease. Within those factors, the disturbances in the production of erythropoietin have the greatest impact on the disease pathogenesis. However, other components such as shortened erythrocyte survival, blood loss, iron or other nutritional deficiencies, hemolysis, the presence of uremic inhibitors of erythropoiesis among others can also significantly contribute to the occurrence of anaemia.

Źródło:

Progress in Health Sciences; 2018, 8(2); 210-214
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 51.

Tytuł:

Percutaneous revascularization of coronary chronic total occlusions – per aspera ad astra!

Autorzy:

Opolski, Maksymilian P.
Rużyłło, Witold

Powiązania:

https://bibliotekanauki.pl/articles/704161.pdf

Data publikacji:

2019

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

coronary chronic total occlusion
percutaneous coronary intervention

Opis:

Patients with coronary chronic total occlusions have usually anginal symptoms, reversible ischemia on stress testing and viable myocardium subtended by the occluded artery. Notwithstanding the optimal clinical characteristics for revascularization by means of percutaneous coronary intervention, the majority of subjects with chronic total occlusions are treated medically or referred for coronary artery bypass grafting. This review highlights the evolution and latest advancements in percutaneous techniques and technologies for revascularization of CTO.

Źródło:

Nauka; 2019, 2
1231-8515

Pojawia się w:

Nauka

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 52.

Tytuł:

Current issues in the diagnostics of paediatric chronic rhinosinusitis

Autorzy:

Standylo, A.
Obuchowska, A.
Horoch, T.
Mielnik-Niedzielska, G.

Powiązania:

https://bibliotekanauki.pl/articles/2098538.pdf

Data publikacji:

2021

Wydawca:

Instytut Medycyny Wsi

Tematy:

pediatrics
diagnostics
chronic rhinosinusitis
child
adolescent
otolaryngology

Opis:

Introduction and objective. Paediatric chronic rhinosinusitis (PCRS) is a common disease in children. It is defined as an ongoing inflammation of the nasal cavity and sinuses lasting for over 12 weeks. Due to prevalence in the population, PCRS is associated with a high healthcare and financial burden. During the examination, attention should be paid to symptoms that may suggest chronic rhinosinusitis (CRS), because it may be underdiagnosed. Due to the chronicity of the inflammatory process and the similarity of symptoms to allergic rhinitis and adenoid hypertrophy, diagnosis and treatment are difficult. In this review, guidelines from The European Position Paper on Rhinosinusitis and Nasal Polyps (EPOS) 2020 and recent literature reports from Medline and Scopus database are analysed. Materials and methods. Information was obtained through a review and analysis of the PubMed Medline and Scopus databases. Brief description of the state of knowledge. Diagnostic difficulties with CRS can be caused by many factors. The EPOS guidelines recommend flexible or rigid nasal endoscopy as a preliminary objective method to assist in the recognition of CRS. Computed tomography (CT) is not recommended for routine management; therefore, CT is the gold standard for imaging when establishing a PCRS diagnosis or preparing for sinus surgery. The use of conventional X-ray imaging for chronic rhinosinusitis is limited and not recommended. Conclusions. Understanding the symptoms of chronic rhinosinusitis is of utmost importance in daily practice. Early initial assessment of symptoms in children with a high probability of CRS allows for early diagnosis and reduces the need for endoscopic and imaging examination.

Źródło:

Journal of Pre-Clinical and Clinical Research; 2021, 15, 3; 134-136
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 53.

Tytuł:

Functional outcomes of tympanoplasty surgery

Autorzy:

Matuszewska, Izabela
Burduk, Paweł
Kaźmierczak, Wojciech
Janiak-Kiszka, Joanna

Powiązania:

https://bibliotekanauki.pl/articles/1398626.pdf

Data publikacji:

2016

Wydawca:

Index Copernicus International

Tematy:

chronic otitis media
Tympanoplasty
pure tone audiometry

Opis:

Objective: We reviewed functional outcomes of tympanoplasty. Study design: The results of tympanoplastic surgery are changing in time. We present late treatment outcomes among different types of tympanoplasty. Methods: Eighty-six patients who underwent tympanoplasty were enrolled in the study. The results of pure tone audiometry performed 7 days before, then at 3 months, 1 year, and 3 years after the surgery were assessed. Type II tympanoplasty involved implantation of a partial ossicular replacement prosthesis and type III tympanoplasty involved reconstruction with a total ossicular replacement prosthesis and the use of autogenous homogenous material. Statistical analysis was performed. Results: With all four types of tympanoplasty, hearing improvement was achieved at 3 months and 1 year after surgery based on the magnitude of the mean ABG reduction (p<0.001). In patients who underwent type I, type III, and type IV tympanoplasty, the ABG reduction at 3 years after surgery was maintained at the level reported at 3 months and 1 year after surgery (p<0.001). In patients who underwent type II tympanoplasty, however, the mean ABG value was increased at all tested frequencies (p<0.05). The mean ABG values reported 3 years after type II and type III tympanoplasty were similar. Conclusions: Based on the results over time, hearing improvement seems to be less durable after reconstruction with the partial ossicular replacement prosthesis procedure compared to the total ossicular replacement prosthesis procedure.

Źródło:

Polish Journal of Otolaryngology; 2016, 70, 6; 12-19
0030-6657
2300-8423

Pojawia się w:

Polish Journal of Otolaryngology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 54.

Tytuł:

Zastosowanie oktenidyny w praktyce lekarza rodzinnego
The use of octenidine in the practice of a family doctor

Autorzy:

Citko, Anna

Powiązania:

https://bibliotekanauki.pl/articles/2200592.pdf

Data publikacji:

2023-04-01

Wydawca:

Wydawnictwo Naukowe Medyk sp. z o.o.

Tematy:

oktenidyna
rany przewlekłe
biofilm
octenidine
chronic wounds

Opis:

Dichlorowodorek oktenidyny należy do grupy antyseptyków, to jest preparatów wykazujących działanie przeciwdrobnoustrojowe na różnych poziomach: na powierzchni rany, w wysięku, w strukturach opatrunku oraz w tkankach. Spektrum działania oktenidyny jest bardzo szerokie i obejmuje bakteryjne formy wegetatywne, bakterie Gram-ujemne, bakterie Gram-dodatnie (w tym MRSA, ORSA, VRSA, VRE), grzyby, wirusy oraz pierwotniaki. Oktenidyna nie wykazuje działania genotoksycznego oraz kancerogennego, a jednocześnie ma niski potencjał cytotoksyczny wobec komórek gospodarza. Szczególne znaczenie oktenidyna odgrywa w leczeniu ran przewlekłych. Utrudniony proces gojenia się jest często związany z obecnością w ranie drobnoustrojów chorobotwórczych, zwłaszcza szczepów wielolekoopornych oraz obecnością biofilmu. Oktenidyna wykazuje swoje działanie przeciwdrobnoustrojowe w ciągu 1 minuty po ekspozycji. Substancja ta charakteryzuje się dobrą penetracją przez struktury biofilmu. Oktenidyna wykazuje skuteczność wobec biofilmu wytworzonego przez patogeny struktur, z których nie jest się w stanie wypłukać zaaplikowanej substancji. Może być skuteczna w leczeniu zakażeń gronkowcowych u pacjentów z atopowym zapaleniem skóry. Co ciekawe, oktenidyna hamuje tworzenie się płytki nazębnej i zmniejsza częstość występowania stanów zapalnych dziąseł. Może być także skutecznym środkiem pomocniczym w leczeniu kandydoz jamy ustnej.

Źródło:

Lek w Polsce; 2023, 383, 4; 34-28
2353-8597

Pojawia się w:

Lek w Polsce

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 55.

Tytuł:

Analysis of relationship between UMOD polymorphisms rs13335818, rs4293393 and rs13333226 and risk of chronic kidney disease caused by chronic glomerulonephritis
Analiza związku polimorfizmów rs13335818, rs4293393 i rs13333226 genu UMOD z występowaniem przewlekłej choroby nerek na tle przewlekłego kłębuszkowego zapalenia nerek

Autorzy:

Żywiec, Joanna
Piecha, Grzegorz
Gola, Mateusz
Kiliś-Pstrusińska, Katarzyna
Więcek, Andrzej
Gumprecht, Janusz
Grzeszczak, Władysław

Powiązania:

https://bibliotekanauki.pl/articles/1035893.pdf

Data publikacji:

2017

Wydawca:

Śląski Uniwersytet Medyczny w Katowicach

Tematy:

przewlekła choroba nerek
przewlekłe kłębuszkowe zapalenie nerek
polimorfizmy genu uromoduliny
chronic kidney disease
chronic glomerulonephritis
uromodulin gene polymorphisms

Opis:

INTRODUCTION: Chronic glomerulonephritis is one of the common causes of chronic kidney disease that can lead to end-stage renal failure and the need for renal replacement therapy. Understanding the aetiology of this disease and its risk factors can help develop new methods of early diagnosis and effective therapy. Uromodulin is a protein with a broad spectrum of activity, and is involved in the key pathways that regulate kidney homeostasis. AIM OF THE STUDY: The aim of the study was to analyse the relationship between three selected polymorphisms (rs13335818, rs4293393 and rs13333226) of the uromodulin gene (UMOD) and the risk of chronic kidney disease caused by chronic glomerulonephritis. MATERIAL AND METHODS: 113 patients with chronic glomerulonephritis and eGFR < 60 ml/min/1.73 m2 (experimental group) and 196 patients from the General Outpatient Clinic without a history of renal disease and eGFR > 60 ml/min/1.73 m2 (control group) were recruited for the study. The study protocol assumed a one-time blood collection for genetic testing and serum creatinine level determination. Genetic material was isolated from the peripheral blood lymphocytes of the subjects. Genotyping of the analysed polymorphisms was performed using TaqMan SNP Genotyping Assay kits. The results were processed with statistical methods using Statistica 10 and Microsoft Office Exel 2003 software, the Mann-Whitney U test and the χ2 test. Statistical significance was adopted at p < 0.05. RESULTS: No statistically significant differences in the distribution of genotypes between the experimental and control groups were found for any of the three analysed UMOD variants. CONCLUSIONS: UMOD polymorphisms rs13335818, rs4293393 and rs13333226 are not associated with the risk of chronic kidney disease caused by chronic glomerulonephritis.
WSTĘP: Przewlekłe kłębuszkowe zapalenie nerek jest jedną z częstych przyczyn przewlekłej choroby nerek mogącej prowadzić do ich schyłkowej niewydolności i konieczności stosowania terapii nerkozastępczej. Poznanie etiologii tej choroby oraz czynników ryzyka daje nadzieję na wdrożenie nowych metod wczesnej diagnostyki i skutecznej terapii. Uromodulina jest białkiem prezentującym szerokie spektrum działań, włączonym w kluczowe szlaki warunkujące homeostazę nerek. CEL PRACY: Celem pracy była ocena związku wybranych trzech polimorfizmów (rs13335818, rs4293393 i rs13333226) genu uromoduliny (UMOD) z występowaniem przewlekłej choroby nerek na tle przewlekłego kłębuszkowego zapalenia nerek. MATERIAŁ I METODY: Do badania zrekrutowano 113 chorych z przewlekłym kłębuszkowym zapaleniem nerek i eGFR < 60 ml/min/1,73 m2 (grupa badana) oraz 196 pacjentów Poradni Ogólnej POZ bez chorób układu moczowego w wywiadzie, z eGFR > 60 ml/min/1,73 m2 (grupa kontrolna). Protokół badania przewidywał jednorazowe pobranie krwi do wykonania badań genetycznych oraz w celu oznaczenia stężenia kreatyniny w surowicy. Materiał genetyczny wyizolowano z limfocytów krwi obwodowej badanych. Genotypowanie badanych polimorfizmów przeprowadzono z wykorzystaniem zestawów TaqMan SNP Genotyping Assay. Uzyskane wyniki opracowano statystycznie na podstawie programów Statistica 10 i Microsoft Office Exel 2003 z wykorzystaniem: testu Manna-Whitneya i testu χ2. Za granice istotności statystycznej przyjęto wartości p < 0,05. WYNIKI: W zakresie żadnego z trzech badanych polimorfizmów UMOD nie stwierdzono znamiennych statystycznie różnic w rozkładzie genotypów pomiędzy grupami badaną a kontrolną. WNIOSKI: Nie wykazano związku polimorfizmów rs13335818, rs4293393 i rs13333226 genu UMOD z występowaniem przewlekłej choroby nerek na tle przewlekłego kłębuszkowego zapalenia nerek.

Źródło:

Annales Academiae Medicae Silesiensis; 2017, 71; 193-203
1734-025X

Pojawia się w:

Annales Academiae Medicae Silesiensis

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 56.

Tytuł:

Chroniczne zmęczenie oraz bezsenność wśród pielęgniarek
Chronic fatigue and insomnia among pediatric nurses

Autorzy:

Dudek, Aleksandra

Powiązania:

https://bibliotekanauki.pl/articles/20214143.pdf

Data publikacji:

2021-09-28

Wydawca:

Państwowa Akademia Nauk Stosowanych we Włocławku

Tematy:

chroniczne zmęczenie
zespół przewlekłego zmęczenia
praca zmianowa
pielęgniarstwo
chronic fatigue
chronic fatigue syndrome
sleep disturbance
insomnia
shift work
nursing

Opis:

Wstęp. Pielęgniarstwo to zawód obciążony wieloma czynnikami. Jednymi z wielu problemów jest praca zmianowa, narażenie na zmęczenie, problemy ze snem, bezsenność. Do czynników społecznych zaliczyć można błędy w komunikacji między personelem i pacjentem. W pracy przybliżono zagadnienie zespołu przewlekłego zmęczenia. Cel. Celem pracy jest ocena chronicznego zmęczenia i bezsenności wśród pielęgniarek oraz określenie jaki wpływ mają one na relacje w zespole pielęgniarskim. Materiał i metody. Populacją, która została poddana badaniu była grupa 100 pielęgniarek pediatrycznych, chirurgicznych, internistycznych oraz podstawowej opieki zdrowotnej. Narzędziami były: Skala Zmęczenia Chronicznego (FAS),  Ateńska Skala Bezsenności (AIS), kwestionariusz ankiety własnego autorstwa. W pracy wykorzystano metodę sondażu diagnostycznego oraz metodę szacowania. Wyniki. Blisko połowa pielęgniarek w grupie badanej miała objawy zmęczenia chronicznego, a 36% pielęgniarek w grupie badanej przejawiała bezsenność. Wnioski. Chroniczne zmęczenie pielęgniarek często jest spowodowane specyfiką oddziałów, na których pracują. Na bezsenność wpływa praca zmianowa, która zwiększa odczuwanie zmęczenia i desynchronizuje biologiczny zegar. Lata stażu nie wpływają znacząco na poziom zmęczenia i senności pielęgniarek. Na bezsenność wpływa praca zmianowa oraz zła organizacja pracy.
Introduction. Nursing is overloaded proffesion. One of many factors causes job problem are: shift work, exposure to fatigue, stress, sleep disturbance and, insomnia. Communication lapses with medical staff and patients are social factors. This essay highlights chronic fatigue syndrom’s problems. Aim. This thesis purpose is chronic fatigue and insomnia level evaluation among nurses and their influence to atmosphere in nurse team. Material and methods. The examined population was a group of 100 pediatric, surgical, internal medicine and primary care nurses. The tools were the Chronic Fatigue Scale (FAS), the Athens Insomnia Scale (AIS), and a self-written questionnaire. Method of a diagnostic survey and the method of estimation. Results. Nearly half of the nurses had symptoms of chronic fatigue, and 36% of the nurses had insomnia. Conclusions. Chronic fatigue of nurses is often caused by the specificity of wards. Shift work and defective work organization contribute to insomnia.

Źródło:

Innowacje w Pielęgniarstwie i Naukach o Zdrowiu; 2021, 6, 3; 38-58
2451-1846

Pojawia się w:

Innowacje w Pielęgniarstwie i Naukach o Zdrowiu

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 57.

Tytuł:

Polypharmacy, medication adherence and medication management at home in elderly patients with multiple non-communicable diseases in Thai primary care

Autorzy:

Vatcharavongvan, Pasitpon
Puttawanchai, Viwat

Powiązania:

https://bibliotekanauki.pl/articles/552602.pdf

Data publikacji:

2017

Wydawca:

Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych

Tematy:

aged
chronic diseases
polypharmacy
primary care
patient adherence.

Źródło:

Family Medicine & Primary Care Review; 2017, 4; 412-416
1734-3402

Pojawia się w:

Family Medicine & Primary Care Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 58.

Tytuł:

Style życia seniorów chorych na cukrzycę
Lifestyles of senior people with diabetes

Autorzy:

Kościńska, Elżbieta

Powiązania:

https://bibliotekanauki.pl/articles/464435.pdf

Data publikacji:

2016

Wydawca:

Akademickie Towarzystwo Andragogiczne

Tematy:

choroba przewlekła
senior
styl życia
chronic disease
lifestyle

Opis:

W artykule zawarte są teoretyczne rozważania na temat choroby przewlekłej, jaką jest cukrzyca oraz nad stylem życia i jego uwarunkowaniach. Autorka przedstawia wyniki badań własnych prowadzonych na temat stylu życia seniorów z cukrzycą typu 2. Na podstawie uzyskanych wyników badań wyodrębniono styl dominujący, najbardziej rozpowszechniony: „Unikanie wyborów egzystencjalnych” i style alternatywne: „Aktywni w sieci ograniczeń”, „Na pograniczu poświęcenia i ofiary”, „Nastawienie na korzystanie z przyjemności życia i »używanie życia«”, realizowane przez nieliczne osoby.
The article contains theoretical reflections on diabetes as a chronic disease, on the lifestyle and its conditioning. The author presents results of her own research on the lifestyle of people with type 2 diabetes. Based on achieved results the prevailing and the most widespread style has been determined as ‘Avoiding existential choices,’ accompanied by alternative styles: ‘Active in the network of restrictions,’ ‘On the border between dedication and sacrifice,’ ‘Focus on enjoying pleasures of life and “using life”, ’ adopted by few.

Źródło:

Edukacja Dorosłych; 2016, 2; 59-70
1230-929X

Pojawia się w:

Edukacja Dorosłych

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 59.

Tytuł:

Selected problems of the relation between pain-immunity and depression

Autorzy:

Ortenburger, Dorota
Rodziewicz - Gruhn, Joanna
Jacek, Wąsik
Marfina, Olga
Polina, Natalya

Powiązania:

https://bibliotekanauki.pl/articles/1031730.pdf

Data publikacji:

2017

Wydawca:

PPHU Projack Jacek Wąsik

Tematy:

chronic pain
closed circle
depression
immunity system
interactions

Opis:

The paper presents selected problems of the coexistence of chronic pain and depression . It has been assumed that chronic pain and depression make two se parate ailments that often coexist. The phenomenon of the coexistence of physical symptoms (including pain) and depression have been widely popularised. Over 65% of patients with pain ailments suffer from depression that is often undiagnosed. The therapi sts specify this phenomenon as a “closed circle”, as it is not known what the beginning of its appearance was. On one hand, pain often hides the symptoms of depression so effectively that its recognition by a physician seems impossible; on the other, it is known that chronic pain causes continual lowering of mood and depression that increases pain ailments. Moreover, the existence of common neurobiological mechanisms makes depression and pain escalate mutually.

Źródło:

Physical Activity Review; 2017, 5; 74-77
2300-5076

Pojawia się w:

Physical Activity Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 60.

Tytuł:

Contemporary storytelling: can writing about negative experiences regarding chronic disease be a way of therapy?

Autorzy:

Osowiecka, Małgorzata
Błajet-Grabowska, Monika

Powiązania:

https://bibliotekanauki.pl/articles/1178900.pdf

Data publikacji:

2017

Wydawca:

Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN

Tematy:

Chronic disease
blog
cancer
coping with
expressive writing

Opis:

Chronic disease is often connected with huge dose of uncertainty. Some sick people suffer from isolation from family and lack of other intimate relationships. Patients struggling with chronic disease seek variety forms of support. One form of coping with a chronic illness is writing about emotions. The main contribution of this article is to present selected forms of coping with chronic disease through expressive writing. Writing a blog is an increasingly popular way of describing patient’s experiences of cancer. It allows patients to express negative emotions such sadness, guilt and loneliness without speaking aloud. We analyzed hundreds of blogs written by women with cancer on most popular websites in Poland in 2016 year. Very important for patients with chronic disease is how they talk about illness and how they treat it. The growing importance of blogging, as well as the increasing availability of various forms of blogging motivate people to try blogging as a way of coping with cancer. It is becoming increasingly a real treatment for cancer patients.

Źródło:

World Scientific News; 2017, 89; 120-125
2392-2192

Pojawia się w:

World Scientific News

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 61.

Tytuł:

Evaluation of renal function in primary care

Autorzy:

Musiałowska, B.
Rudzińska, M.
Koc-Żórawska, E.
Żórawski, M.

Powiązania:

https://bibliotekanauki.pl/articles/1918735.pdf

Data publikacji:

2018

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

chronic kidney disease
acute kidney injury
Primary Care

Opis:

Evaluation of renal function is one of the primary tools used in treatment and monitoring kidney injury such as acute kidney injury (AKI) or chronic kidney disease (CKD) in Primary Care patients. Accompanying chronic diseases also have an impact on the assessment of renal function, treatment monitoring and adjustment of drug doses.

Źródło:

Progress in Health Sciences; 2018, 8(2); 202-205
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 62.

Tytuł:

Partial remission in patient with Richter syndrome: an „emergency” treatment with pixantrone

Autorzy:

Szwedyk, Paweł

Powiązania:

https://bibliotekanauki.pl/articles/1035640.pdf

Data publikacji:

2020-06-30

Wydawca:

Medical Education

Tematy:

Richter syndrome
chemotherapy
chronic lymphocytic leukemia
immunotherapy
pixantrone

Opis:

Chronic lymphocytic leukemia is the most commonly recognized type of leukemia in adults. The appearance of systemic symptoms such as weight loss, fever, or local symptoms in the form of rapidly growing organomegaly, lymphadenopathy in a patient with CLL raises the suspicion of transformation into a high-grade lymphoma – defined as Richter syndrome which is usually associated with very poor prognosis. The described case concerns a 71-year-old patient with this diagnosis, in whom due to the confirmed resistance to subsequent lines of immuno- and chemotherapy, an „emergency” treatment with a modern chemotherapy drug from the aza-anthracendion group – pixantrone was used. Treatment with pixantrone was associated with a relatively good response, translating into partial remission (also in the area of infiltrative changes in the head and neck structures), stabilization of the course of the disease and, consequently, allowed to extend the patient’s life.

Źródło:

OncoReview; 2020, 10, 2; 52-56
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 63.

Tytuł:

The effect of tyrosine kinase inhibitors used in the treatment of chronic myeloid leukemia on the cardiovascular system

Autorzy:

Sacha, Tomasz
Góra-Tybor, Joanna
Szmit, Sebastian

Powiązania:

https://bibliotekanauki.pl/articles/1035757.pdf

Data publikacji:

2019

Wydawca:

Medical Education

Tematy:

cardiovascular toxicity
chronic myeloid leukemia
tyrosine kinase inhibitors

Opis:

The use of tyrosine kinase inhibitors (TKIs) in the treatment of chronic myeloid leukemia has significantly improved the prognosis and outcomes for most patients. Clinical trials indicate that long-term CML therapy requires the introduction of second- or third-generation inhibitors in approximately 40–50% of cases. Effective in the case of imatinib resistance or intolerance, second generation TKI’s can also be used as a first-line treatment, leading to a faster, and deeper molecular response. TKIs, however, have also been observed to cause significant late adverse effects, including cardiovascular complications, which may raise certain safety concerns. The excellent treatment outcomes achieved with tyrosine kinase inhibitors have led to a gradual increase in the number and age of treated patients, and the associated higher incidence and severity of age-related co-morbidities such as diabetes, hypercholesterolemia, atherosclerosis, ischemic heart disease, hypertension, and congestive heart failure, which raise the risk of treatment-related cardiovascular complications. The article discusses the effects of individual TKIs on the pathogenesis of cardiovascular complications and presents the results of clinical trials that studied their impact on the incidence of such events.

Źródło:

OncoReview; 2019, 9, 1; 3-21
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 64.

Tytuł:

Radon-enriched hot spring water therapy for upper and lower respiratory tract inflammation

Autorzy:

Passali, Desiderio
Gabelli, Giacomo
Passali, Giulio Cesare
Mösges, Ralph
Bellussi, Luisa Maria

Powiązania:

https://bibliotekanauki.pl/articles/1398521.pdf

Data publikacji:

2017

Wydawca:

Index Copernicus International

Tematy:

Balneology
Allergic Rhinitis
Chronic Rhino sinusitis
Asthma
Radon

Opis:

Background Radon-222-enriched hot spring therapy, which is characterized by a safe level of radioactivity, is used for the treatment of rheumatic disorders, and its efficacy has already been studied in several clinical trials. Radon-water inhalation therapy for the treatment of upper and lower airway inflammatory diseases is used in many hot springs centers. However, its application has not been reviewed to date. Methods We systematically searched the PubMed and Scopus databases for clinical trials published in the last 20 years in which objective parameters of upper and lower airway function had been tested before and after radon-enriched inhalation treatment. Results Four prospective studies were found: 1 asthma trial, 1 placebo-controlled chronic rhinosinusitis trial, 1 upper respiratory tract inflammation with nasal obstruction trial, and 1 case-control allergic rhinitis trial. Patients were treated with nasal inhalations of radon-enriched water for 12 to 28 days and were assessed at baseline and after therapy. After 2 weeks of treatment, nasal resistance decreased, flow increased, mucociliary clearance was enhanced, ciliated-to-muciparous cell ratio increased, and %FEV1 increased in asthmatic patients. Conclusion Radon-enriched inhalation therapy improves objective indicators of nasal function in allergic rhinitis and chronic rhinosinusitis, and causes relief of pulmonary obstruction in asthma.

Źródło:

Polish Journal of Otolaryngology; 2017, 71, 4; 8-13
0030-6657
2300-8423

Pojawia się w:

Polish Journal of Otolaryngology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 65.

Tytuł:

Hearing loss in patients with extracranial complications of chronic otitis media

Autorzy:

Przewoźny, Tomasz
Kuczkowski, Jerzy

Powiązania:

https://bibliotekanauki.pl/articles/1398541.pdf

Data publikacji:

2017

Wydawca:

Index Copernicus International

Tematy:

chronic suppurative otitis media
complications
extracranial
hearing loss

Opis:

Objective: A pure tone audiomety analysis of patients with extracranial complications of chronic suppurative otitis media (ECCSOM). Material and methods: We retrospectively analyzed audiometric data performed before treatment from 63 patients with ECCSOM (56 single, 7 multiple complications) including groups of frequencies. Results: The greatest levels of hearing loss were noted for 6 and 8 kHz (79.0 and 75.7 dBHL) and for the frequency groups high tone average (76.1 dBHL). As regards the severity of hearing impairment in pure tone average the prevalence of complications was as follows: labyrinthitis (77.8±33.6 dBHL), facial palsy (57.1±14.3 dBHL), perilymphatic fistula (53.9±19.9 dBHL) and mastoiditis (42.2±9.5 dBHL) (p=0.023). Conclusions: Hearing loss in ECCSOM is dominated by mixed, high-tone, moderate type of hearing loss, most profound in labyrinthitis. In 11% of patients the complication causes total deafness.

Źródło:

Polish Journal of Otolaryngology; 2017, 71, 3; 31-41
0030-6657
2300-8423

Pojawia się w:

Polish Journal of Otolaryngology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 66.

Tytuł:

Parotid gland tumors. Results of retrospective analysis of 149 patients treated at the Clinical Department of Cranio-Maxillofacial Surgery, Clinic of Otolaryngology and Oncologic Laryngology of Military Institute of Medicine in Warsaw in years 2006–2016.

Autorzy:

Chloupek, Aldona
Zarzycki, Krzysztof
Dąbrowski, Jarosław
Domański, Wojciech

Powiązania:

https://bibliotekanauki.pl/articles/1398551.pdf

Data publikacji:

2017

Wydawca:

Index Copernicus International

Tematy:

chronic suppurative otitis media
complications extracranial
hearing loss

Opis:

Wstęp: Nowotwory mające swoją etiologię w gruczołach ślinowych występują rzadko i stanowią ok. 3–10% wszystkich guzów w obrębie głowy i szyi. Materiał i metody: W latach 2006–2016 w Klinicznym Oddziale Chirurgii Czaszkowo-Szczękowo-Twarzowej Wojskowego Instytutu Medycznego w Warszawie z powodu nowotworów ślinianek przyusznych hospitalizowano i leczono 149 pacjentów. Podstawą do analizy były historie chorób pacjentów, wyniki badań histopatologicznych oraz protokoły zabiegów operacyjnych. Wyniki: W 126 przypadkach guzy były łagodne, natomiast w 26 guzy złośliwe. Analizując wyniki można stwierdzić, że nowotwory - zarówno łagodne, jak i złośliwe – częściej występowały u mężczyzn. Średni wiek całej grupy badanych wynosił 58,3 lat, dla zmian złośliwych – 65,5 lat, a dla zmian łagodnych był nieznacznie niższy i wynosił 56,9 lat. Wśród pacjentów objętych analizą szczyt zachorowalności przypadał na przedział wiekowy 60–69 lat. Ponadto zwraca uwagę, iż przedział ten był taki sam dla ogólnej liczby guzów, jak i nowotworów łagodnych, natomiast dla nowotworów złośliwych był nieznacznie wyższy i wynosił 70–79 lat. Z analizy zebranego materiału wynika, że guzy łagodne występowały znamiennie częściej, stanowiąc 84,56% wszystkich guzów. Najczęstszymi rozpoznaniami wśród nowotworów łagodnych były gruczolak wielopostaciowy (adenoma pleomorphicum) oraz gruczolak limfatyczny (adenolymphoma), które stanowiły łącznie 93,66%. Rezultaty badań wskazują, że wśród nowotworów złośliwych dominowały: gruczolakorak polimorficzny o niskiej złośliwości (polymorphous low-grade adenocarcinoma) występujący w 26,07% przypadków, gruczolakorak inaczej nieokreślony (adenocarcinoma NOS) oraz rak zrazikowokomórkowy (acinic cell carcinoma). Każdy z nich stanowił po 13,04% rozpoznań. Jak wynika z przeprowadzonej analizy najczęstszą metodą leczenia było leczenie chirurgiczne jako metoda stosowana samodzielnie. Wnioski: Uzyskane z retrospektywnej analizy dane korelują z piśmiennictwem krajowym i światowym.

Źródło:

Polish Journal of Otolaryngology; 2017, 71, 3; 42-47
0030-6657
2300-8423

Pojawia się w:

Polish Journal of Otolaryngology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 67.

Tytuł:

Rare case of Richter’s syndrome localization in liver and thyroid of a patient with a chronic lymphocytic leukemia (CLL) - case report and literature

Autorzy:

Wasik-Szczepanek, E.
Szymczyk, A.
Szczepanek, D.
Grywalska, E.
Szumiło, J.
Trojanowski, P.
Czabak, O.
Hus, M.

Powiązania:

https://bibliotekanauki.pl/articles/2085452.pdf

Data publikacji:

2020

Wydawca:

Instytut Medycyny Wsi

Tematy:

liver
thyroid
chronic lymphocytic leukemia
Richter’s syndrome

Opis:

Richter’s syndrome (RS) is a rare complication in which chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL) transforms into a more aggressive type of lymphoma – diffuse large B cell lymphoma (DLBCL), or Hodgkin’s lymphoma (HL). The review describes the clinical case of a patient with CLL and RS diagnosis. A computed tomography (CT) scan of the abdominal cavity detected numerous normodense areas in the liver. Simultaneously, ultrasound examination (USG) of the thyroid revealed the presence of a solid hypoechogenic lump. The material sampled from closed biopsies of liver and thyroid in both cases allowed the diagnosis of diffuse large B cell lymphoma (DLBCL). The liver and the thyroid are particularly rare locations of RS. However, those cases allowed the conclusion that RS may occur even in a very unexpected and less probable location.

Źródło:

Annals of Agricultural and Environmental Medicine; 2020, 27, 1; 160-164
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 68.

Tytuł:

Effect of body weight on disability and chronic disease rates in the elderly in south-eastern Poland

Autorzy:

Ćwirlej-Sozańska, A.B.
Wiśniowska-Szurlej, A.
Wilmowska-Pietruszyńska, A.
Sozański, B.
Mazur, A.

Powiązania:

https://bibliotekanauki.pl/articles/2085581.pdf

Data publikacji:

2020

Wydawca:

Instytut Medycyny Wsi

Tematy:

aged
disability evaluation
chronic disease
body mass index

Opis:

Introduction and objective. The rapid aging of the human population is an increasing challenge to public health. Effective strategies are required to prevent disability and dependency of the elderly. This study aimed to evaluate the effect of body weight on the prevalence of disability and chronic diseases among 60–80-year-old people living in south-eastern Poland. Materials and method. The study included 1,800 randomly selected people aged 60–80 years living in the Podkarpackie region of south-eastern Poland. Respondents, holders of a – personal identification number (PESEL), were randomly drawn by the Ministry of Interior and Administration (MSWiA) in Poland. The study was conducted in the form of a face-to-face interview at the respondent’s residence. The WHODAS 2.0 questionnaire was used to assess disability and functioning. Socio-demographic data were also collected, and the body weight measured in 5% of the respondents after completion of the study. Statistical analysis was performed using Statistica 10. Results. Respondents with Body Mass Index (BMI)<18.5 and BMI ≥35.0 had significantly higher disability levels than those in the normal weight and overweight categories. The greatest limitations were found in participating in everyday life, household activities, getting along and mobility. There was also a statistically significant relationship between BMI and the number of chronic diseases (p<0.001). Conclusions. When planning a healthcare strategy for people aged 60–80 living in Poland, additional support should be provided to those at risk in the categories of underweight and obesity. The obtained findings indicate that the health behaviour of seniors should be assessed – especially regarding their diet and eating habits, physical activity, and participation in social life – in order to tailor prevention programmes specifically to their needs.

Źródło:

Annals of Agricultural and Environmental Medicine; 2020, 27, 2; 240-247
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 69.

Tytuł:

Atorvastatin improves tubular status in non-diabetic patients with chronic kidney disease - placebo controlled, randomized, cross-over study

Autorzy:

Renke, Marcin
Tylicki, Leszek
Rutkowski, Przemysław
Neuwelt, Alexander
Larczyński, Wojciech
Ziętkiewicz, Marcin
Aleksandrowicz, Ewa
Łysiak-Szydłowska, Wiesława
Rutkowski, Bolesław

Powiązania:

https://bibliotekanauki.pl/articles/1040322.pdf

Data publikacji:

2010

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

proteinuria
kidney
tubular injury
chronic kidney disease
Atorvastatin

Opis:

Background. There is evidence that dyslipidemia is associated with chronic kidney disease (CKD) and it has been implicated in the progression of renal damage. Optimal management of dyslipidemia should therefore lead to renal benefits. A number of experimental models demonstrate a beneficial effect of statins in ameliorating renal damage. However, the exact mechanism by which statins protect against renal damage remains unclear. Methods. In a placebo-controlled, randomized, cross-over study we evaluated the influence of atorvastatin (ATO) 40 mg/day added to the renin-angiotensin-aldosterone systeme (RAAS) blockade on proteinuria and surrogate biomarkers of tubular damage or injury in 14 non-diabetic patients with proteinuria (0.4-1.8 g per 24 h) with normal or declined kidney function (eGFR 55-153 ml/min). In the eight-week run-in period, therapy using angiotensin converting enzyme inhibitors (ACEI) and/or angiotensin II subtype 1 receptor antagonists (ARB) was adjusted to achieve a blood pressure below 130/80 mm Hg. Next, patients were randomly assigned to one of two treatment sequences: ATO/washout/placebo or placebo/washout/ATO. Clinical evaluation and laboratory tests were performed at the randomization point and after each period of the study. The primary end point of this study was a change in proteinuria measured as 24-h urine protein excretion (DPE). Secondary end points included urine N-acetyl-β-d-glucosaminidase (NAG) and α1-microglobulin (α1m) excretion. Results. The ATO therapy significantly reduced urine excretion of α1m (p=0.033) and NAG (p=0.038) as compared to placebo. There were no differences in proteinuria, blood pressure, eGFR and serum creatinine between the ATO and placebo groups. Conclusion. Atorvastatin treatment is safe and improves biomarkers of tubular damage or injury in non-diabetic patients with CKD.

Źródło:

Acta Biochimica Polonica; 2010, 57, 4; 547-552
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 70.

Tytuł:

Endothelial progenitor cells participation in cardiovascular and kidney diseases: a systematic review

Autorzy:

Kiewisz, Jolanta
Kaczmarek, Monika
Pawlowska, Anna
Kmiec, Zbigniew
Stompor, Tomasz

Powiązania:

https://bibliotekanauki.pl/articles/1038766.pdf

Data publikacji:

2016

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

endothelial progenitor cells
chronic kidney diseases
cardiovascular diseases.

Opis:

Endothelial progenitor cells (EPCs) represent a small population of blood cells (5-40 cells/mm3), with an ability to differentiate into endothelial cells that form the lining of the blood vessels and contribute to postnatal angiogenesis. Abundant evidence shows that recruitment of EPCs from the bone marrow, the monocyte/macrophage lineage and the organs facilitate the endothelial regeneration and repair. Changes in the number of EPCs were observed in both, chronic kidney and cardiovascular diseases. Thus, these cells were tested for usage in diagnosis and therapy. In this paper, we review the current knowledge on the EPC biology and contribution of these cells to the kidney and cardiovascular diseases.

Źródło:

Acta Biochimica Polonica; 2016, 63, 3; 475-482
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 71.

Tytuł:

Mitochondrial mutagenesis in BCR-ABL1-expressing cells sensitive and resistant to imatinib

Autorzy:

Blasiak, Janusz
Hoser, Grazyna
Bialkowska-Warzecha, Jolanta
Pawlowska, Elzbieta
Skorski, Tomasz

Powiązania:

https://bibliotekanauki.pl/articles/1038829.pdf

Data publikacji:

2016

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

Imatinib
chronic myeloid leukemia
BCR-ABL1 gene

Opis:

Imatinib revolutionized the treatment of chronic myeloid leukemia (CML) with the expression of the BCR-ABL1 tyrosine kinase, but imatinib resistance is an emerging problem. Imatinib can hinder the inhibitory effects of BCR-ABL1 on mitochondrial apoptotic pathway, so mitochondrial mutagenesis can be important for its action. To explore the mechanisms of imatinib resistance we created a mouse-derived CML model cells consisting of parental 32D cells (P) and cells transfected with the BCR-ABL1 gene (S cells) or its variants with the Y253H or T315I mutations (253 and 315 cells, respectively), conferring resistance to imatinib. A fraction of the S cells was cultured in increasing concentrations of imatinib, acquiring resistance to this drug (AR cells). The 253, 315 and AR cells, in contrast to S cells, displayed resistance to imatinib. We observed that the T315I cells displayed greater extent of H2O2-induced mtDNA damage than their imatinib-sensitive counterparts. No difference in the sensitivity to UV radiation was observed among all the cell lines. A decrease in the extent of H2O2-induced mtDNA damage was observed during a 120-min repair incubation in all cell lines, but it was significant only in imatinib-sensitive and T315I cells. No difference in the copy number of mtDNA and frequency of the 3,867-bp deletion was observed and genotoxic stress induced by H2O2 or UV did not change this relationship. In conclusion, some aspects of mtDNA mutagenesis, including sensitivity to oxidative stress and DNA repair can contribute to imatinib resistance in BCR-ABL1-expressing cells.

Źródło:

Acta Biochimica Polonica; 2016, 63, 2; 365-370
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 72.

Tytuł:

Giardiosis complicated with mycosis

Autorzy:

Materla, S.
Malecka-Panas, E.
Lipczyk, J.
Planeta-Malecka, I.
Kurnatowska, A.

Powiązania:

https://bibliotekanauki.pl/articles/838815.pdf

Data publikacji:

1998

Wydawca:

Polskie Towarzystwo Parazytologiczne

Tematy:

disease
infection
giardiasis
mycosis
child
Candida
chronic giardiasis

Źródło:

Annals of Parasitology; 1998, 44, 3
0043-5163

Pojawia się w:

Annals of Parasitology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 73.

Tytuł:

The Construction of Self-Identity in the Chronically Mentally Ill: A Focus on Autobiographic Narratives of Mentally Ill Patients in South Korea

Autorzy:

Nam, Sang-hui

Powiązania:

https://bibliotekanauki.pl/articles/2138435.pdf

Data publikacji:

2008-04-30

Wydawca:

Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego

Tematy:

Psychiatry
Chronic mental illness
Autobiographic narratives
Biographical methods

Opis:

A systematic policy for treatment and management of chronic psychiatric patients in South Korea was begun with the passage of the Mental Health Act in 1995. The mentally ill patients who were previously separated from the society now have opportunities to live in local communities under medication with the help of rehabilitation facilities. This study aims to understand how mentally ill patients deal with their new medical environment. An autobiographic narrative analysis is methodically applied in order to link the social and the individual levels. Autobiographic narratives of illness show how the patient’s self-identity is formed and further developed according to the chronic conditions of his illness and the continual learning from experiences. In regard to the construction of selfidentity, two aspects should be taken into consideration: First, medication is absolutely necessary before patients can leave the hospital and participate in rehabilitation programs. Secondly, social integration is usually evaluated by the return of the patient into a normal biographical stage. It turns out that medication deprives the patients of control over their emotions, their bodies. Furthermore, their social environments – including family, friends and the labor market – work against them. Under these circumstances, mentally ill patients are liable to adhere to their own interpretation of mental illness, and what they experience is far different from the expectations of experts in the field. The new mental health environment also contributes to the formation of patient communities. As a result, chronic psychiatric patients are able to build their own subculture and to see themselves through their own eyes. Further studies are needed to explore whether and to what extent the ongoing improvement of social conditions for mentally ill patients has an impact on autobiographic narratives and self-identity construction.

Źródło:

Qualitative Sociology Review; 2008, 4, 1; 150-170
1733-8077

Pojawia się w:

Qualitative Sociology Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 74.

Tytuł:

Uczestnictwo w zajęciach lekcyjnych i pozalekcyjnych w zależności od stanu zdrowia uczniów oraz wybranych czynników kontekstowych

Autorzy:

Berkowska, Aleksandra
Kowalewska, Anna
Mazur, Joanna

Powiązania:

https://bibliotekanauki.pl/articles/1789410.pdf

Data publikacji:

2019-11-04

Wydawca:

Uniwersytet Warszawski. Wydawnictwa Uniwersytetu Warszawskiego

Tematy:

health
chronic diseases
education
school activities
extracurricular activities

Opis:

The article is devoted to the problem of pupils’ perception of difficulties in participating in classes and extracurricular activities. The research was carried out in Poland as part of the international HBSC (Health Behavior in School-aged Children) study in the school year 2013/2014. Data refer to 3,448 schoolkids who completed an extended questionnaire about functioning in a school environment. The research covered five school years – from the fifth grade of primary school to the third grade of lower secondary school. The average age of the respondents was 14.2 years (SD = 1.7). The aim of this work was to compare the pupils’ perception of difficulties in access to school and extracurricular activities depending on the health conditions and selected socio-demographic factors. The obtained results indicate that only one in five pupils declared complete lack of difficulty. The results of the average values of the scale of “restrictions on participation in extracurricular activities and after-school programmes” showed a significant relationship with the sex and wealth of the family, to the detriment of boys and poor families. Pupils with diseases and health problems more often declared that they had difficult access to school and extracurricular activities. Analyses taking into account the state of health of the respondents and the socio-economic status of the family and place of residence indicated that these differences are not offset by children from rich families living in medium-sized cities. An important task of the school in order to equalise educational opportunities is to diagnose the needs related to the students’ health conditions but also taking into account environmental conditions.

Źródło:

Kwartalnik Pedagogiczny; 2019, 64(3 (253)); 207-222
0023-5938

Pojawia się w:

Kwartalnik Pedagogiczny

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 75.

Tytuł:

Quality of life after inguinal hernia repair

Autorzy:

Iftikhar, Nazish
Kerawala, Asad Ali

Powiązania:

https://bibliotekanauki.pl/articles/1391538.pdf

Data publikacji:

2021

Wydawca:

Index Copernicus International

Tematy:

chronic pain
hernia
inguinal
mesh
quality of life

Opis:

Introduction: Inguinal hernias are the most commonly presented abdominal hernias with approximately 20 million people operated annually throughout the world. Severe chronic pain after hernia repair effects social life, daily activity and overall quality of life. The Short Form-36 is (SF-36) a validated indicator of overall health status. Studies have shown that the reliability of the SF-36 is exceeding 0.80. Aim: Our aim of study is to determine the effect of unilateral open mesh repair by using SF-36 on pain control and quality of life of patient. Methods: This cross-sectional study was carried out at Indus Hospital Karachi from 1st April 2018 to 10th September 2018. 88 patients were enrolled in this study according to the inclusion and exclusion criteria. A written and informed consent was taken from all of them. After surgery they were sent home on painkillers. They were called at 4 weeks and were required to fill a pre designed questionnaire Short form-36. Results: Results showed that out of the 88 patients enrolled in this study 35 (39.8%) experienced mild pain, 37 (42%) experience moderate pain and only 16 (18.2%) experienced severe pain. Quality of life was satisfactory in 72 (81%) and unsatisfactory in 13 (14.7%). Conclusion: Hence it is concluded that post operatively patients experienced better physical functioning and emotional role functioning whereas their perceptions about their general health and energy were satisfactory. Hernia surgery should be offered to all the patients with a clinically detectable hernia.

Źródło:

Polish Journal of Surgery; 2021, 93, 3; 35-39
0032-373X
2299-2847

Pojawia się w:

Polish Journal of Surgery

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 76.

Tytuł:

Tonsillectomy in own material

Autorzy:

Bant, Przemysław
Szczygielski, Kornel
Cierniak, Szczepan
Kosek, Jarosław
Kania, Joanna
Sienicki, Rafał
Jurkiewicz, Dariusz

Powiązania:

https://bibliotekanauki.pl/articles/1397346.pdf

Data publikacji:

2020

Wydawca:

Index Copernicus International

Tematy:

chronic tonsillitis
histopathological examination
palatine tonsil
tonsillar hyperthrophy

Opis:

Introduction: Tonsillectomy belongs to the most frequently performed surgical treatments; however, the necessity of its performance is questioned. Therefore, there are many attempts to unify and define the indications for the procedure. Aim: The main objective of the current dissertation was an analysis of the clinical symptoms occurring in patients qualified for tonsillectomy, as well as a comparison of those with a histopathological image of the removed tonsils in a repeatedly carried out, unified pathomorphological examination. The secondary objective was the designation of the demographic profile, existing comorbidities, and complications in the form of postoperative bleeding in patients after tonsillectomy in own material. Material and method: A retrospective analysis of 301 procedures of palatine tonsil removal was performed, which were completed in the years 2017–2019 at the Department of Otolaryngology with Division of Cranio-Maxillo-Facial Surgery of the Military Institute of Medicine, Warsaw, Poland. The indications were defined on the grounds of data from the anamnesis. Based on unified criteria, the removed material was divided into 2 groups: with the signs of Chronic Tonsillitis (CT) as well as Tonsillar Hyperthrophy (TH). Results: The average size of tonsils was the greatest in a group of patients under 35 years of age, and smallest in the group over 51 years of age. As patients aged, the reduction in size of the palatal tonsils was observed. In the examined group, the histopathological diagnosis in the form of HT was found in 165 patients (54.8%), while CT in 136 (45.2%). It was proven that the larger the tonsils in the clinical picture, the more often the histopathological image responded to HT. Among clinical symptoms reported by patients qualified for tonsillectomy, the following were observed: recurring tonsil inflammation in 211 (70.1%), snoring and sleep apnea in 47 (15.6%), as well as sleep apnea in 33 (11%) patients. Primary bleeding occurred in 10 patients (3.34%), and secondary in 8 patients (2.66%). The most common comorbidities were cardiovascular burdens. Conclusions: For most cases, clinical symptoms were confirmed by adequate features of removed material in histopathological examination. The most common histopathological diagnosis was tonsillar hyperthrophy.

Źródło:

Polish Journal of Otolaryngology; 2020, 74, 6; 29-34
0030-6657
2300-8423

Pojawia się w:

Polish Journal of Otolaryngology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 77.

Tytuł:

Hearing loss in mild OSAS and simple snoring patients

Autorzy:

Spinosi, Maria Carla
D'Amico, Francesca
Passali, Giulio
Cingi, Cemal
Rodriguez, Hugo
Passali, Desiderio

Powiązania:

https://bibliotekanauki.pl/articles/1398309.pdf

Data publikacji:

2017

Wydawca:

Index Copernicus International

Tematy:

hearing loss
OSAS
snoring
chronic noise
auditory damage

Opis:

Introduction Obstructive Sleep Apnea Syndrome (OSAS) is characterized by recurrent episodes of prolonged partial or complete obstruction of the upper airways. Several study groups studied the effect of snoring and OSAS on auditory function, showing an increase in the incidence of hearing loss in apneic patients, an earlier onset and/or a degree of hearing loss deeper than in peers. The aim of our study is to evaluate the audiological performance of a population of simple-snoring patients and patients suffering from mild OSAS, and the impact that such pathological condition can have on the auditory function, considering the significant levels of chronic noise. Materials and Methods Data was collected by analyzing audiometric exams on snoring patients and a control group of non-snoring patients. Our study included simple snoring patients without OSAS (AHI < 5) or with low level of OSAS (5< AHI < 15). Possible hearing loss was classified in a crescent scale (A-B-C-D-E), from greater to minor auditory performance, according to the indications of the national protocol of occupational medicine for evaluation of hearing loss in patients exposed to chronic noise. Results We have found independence between simple snorers, mild-OSAS snorers and non-snoring patients compared to the scale of hearing performance classification. Conclusions Our results show a distribution of hearing loss in the different groups that appear independent of the presence or absence of snoring, complicated or uncomplicated by mild OSAS.

Źródło:

Polish Journal of Otolaryngology; 2017, 71, 2; 12-16
0030-6657
2300-8423

Pojawia się w:

Polish Journal of Otolaryngology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 78.

Tytuł:

The use of petrosectomy in cochlear implant surgery

Autorzy:

Amernik, Katarzyna
Niemczyk, Kazimierz
Twardowska, Renata
Jaworowska, Ewa

Powiązania:

https://bibliotekanauki.pl/articles/1399062.pdf

Data publikacji:

2020

Wydawca:

Index Copernicus International

Tematy:

cholesteatoma
chronic otitis
cochlear implant
hearing loss
petrosectomy

Opis:

Introduction: The treatment and rehabilitation of hypoacusis with the use of cochlear implants is a safe and reliable method suitable for both children and adults. In people affected by chronic otitis media cholesteatomatosa or such who have previously undergone open repair of the ear, we use a special surgical technique known as lateral/subtotal petrosectomy. Material and methods: The study group consisted of patients with profound bilateral sensorineural hearing loss, in which otitis media with and without cholesteatoma has been diagnosed or after open repair of the middle ear. A retrospective analysis of patient data, as well as radiological and audiological results, was conducted. Results: In the Clinic of Otolaryngology and Laryngological Oncology of the Pomeranian Medical University in the years 2008–2018 we performed 90 cochlear implant surgeries, including a petrosectomy in 1 child with cholesteatoma (5 years) and in 2 adults after open repair (62 and 73 years). In all cases the procedure was done in a single stage. Healing proceeded correctly in all patients undergoing petrosectomy. The observation period ranges from 26 to 32 months, computed tomography examinations revealed no indirect characteristics of recurrent cholesteatoma. The patients remain under constant ENT supervision. The child has risk factors for autism and mental retardation, he displays good auditory responses and speech understanding; he has not developed active speech. As regarding free field pure tone audiometry, in adults hearing in the cochlear implant remains at 35 and 40 dB, and speech understanding at 80%. Discussion: Patients with chronic otitis media can be treated efficiently and safely with a cochlear implant using lateral petrosectomy. Lateral/subtotal petrosectomy is the access of choice when deep sensorimotor hearing loss coexists with chronic inflammation in the middle ear.

Źródło:

Polski Przegląd Otorynolaryngologiczny; 2020, 9, 2; 1-6
2084-5308
2300-7338

Pojawia się w:

Polski Przegląd Otorynolaryngologiczny

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 79.

Tytuł:

Rodzinny wymiar troski – rola opiekuna osoby z chorobą Alzheimera

Autorzy:

Szluz, Beata

Powiązania:

https://bibliotekanauki.pl/articles/614505.pdf

Data publikacji:

2017

Wydawca:

Uniwersytet Marii Curie-Skłodowskiej. Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej

Tematy:

family
family caregiver
chronic illnesses
chronic health problems
Alzheimer’s disease
rodzina
opiekun rodzinny
choroby przewlekłe
przewlekłe problemy zdrowotne
choroba Alzheimera

Opis:

Most patients have families that are providing some level of care and support. In the case of older adults and people with chronic disabilities of all ages, this “informal care” can be substantial in scope, intensity, and duration. Family care giving raises safety issues in two ways. First, caregivers are sometimes referred to as “secondary patients”, who need and deserve protection and guidance. Second, family caregivers are unpaid help providers who often need help to learn how to become competent volunteer workers who can better protect their family members (i.e. the care recipients). This article summarizes quality evidence from both of these perspectives. The focus is on the adult caregiver who provides care and support primarily for adults with chronic illnesses and chronic health problems.
Większość osób chorych posiada rodziny, które zapewniają pewien poziom opieki i wsparcia. W przypadku osób starszych i osób przewlekle niepełnosprawnych w każdym wieku ta „nieformalna opieka” może mieć znaczny zakres, intensywność i czas trwania. Opieka rodzinna podnosi kwestie bezpieczeństwa na dwa sposoby. Po pierwsze, opiekunowie są czasami określani jako „drugorzędni pacjenci”, którzy potrzebują i zasługują na ochronę i poradnictwo. Po drugie, opiekunowie rodzinni są nieopłacanymi dostawcami, którzy często potrzebują pomocy, aby dowiedzieć się, jak stać się kompetentnym opiekunem, który może lepiej chronić swoich członków rodziny, tj. biorców opieki. W niniejszym opracowaniu przedstawiono przykłady dotyczące jakości życia w kontekście tych dwu spojrzeń. Akcent położono na opiekuna osoby dorosłej, który zapewnia opiekę i wsparcie głównie osobom dorosłym z przewlekłymi chorobami i przewlekłymi problemami zdrowotnymi.

Źródło:

Annales Universitatis Mariae Curie-Skłodowska, sectio J – Paedagogia-Psychologia; 2017, 30, 4
0867-2040

Pojawia się w:

Annales Universitatis Mariae Curie-Skłodowska, sectio J – Paedagogia-Psychologia

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 80.

Tytuł:

The mutual cooperation of blood platelets and lymphocytes in the development of autoimmune thyroid diseases

Autorzy:

Tomczyńska, Małgorzata
Saluk-Bijak, Joanna

Powiązania:

https://bibliotekanauki.pl/articles/1038518.pdf

Data publikacji:

2018

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

autoimmune thyroid diseases
autoantibodies
blood platelets
chronic inflammation
lymphocytes

Opis:

Autoimmune thyroid diseases include several distinct clinical entities, mainly Graves' disease and Hashimoto's thyroiditis. An incompetent immune response directed against the body's own tissues, and the production of antibodies against specific cell antigens accompanied by chronic inflammation, all occur in autoimmune thyroid diseases. The autoimmune process is induced by genetic and environmental factors that are difficult to identify and generates the development of concomitant diseases in other systems. Leukocyte activation and overproduction of inflammatory mediators, as well as improper levels of thyroid hormones, play an essential role in the chronic course of these diseases. The development of autoimmune thyroid diseases results from the impairment of the regulatory and suppressor functions of T-cells or NK cells and activation of B cells, or from the changes in the number of those cells. Many reports have shown the significant role of platelet-leukocyte interaction in inflammation. Autoantibodies react with target antigens in different kinds of cells, including blood platelets, and autoimmune processes can modulate the mutual cooperation of blood platelets and lymphocytes. The activity of blood platelets and lymphocytes is reciprocally regulated. It has been suggested that blood platelets can influence lymphocyte function by direct contact with receptors, and indirectly via soluble mediators. The interactions of platelet-immune cells (neutrophils, monocytes, lymphocyte and dendritic cells) can have a potent enhancing effect on immune cells functions.

Źródło:

Acta Biochimica Polonica; 2018, 65, 1; 17-24
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 81.

Tytuł:

OPINIONS OF PHARMACISTS ON COMMUNITY PHARMACY-BASED HEALTH SCREENINGS FOR COMMON CHRONIC DISEASES

Autorzy:

Waszyk-Nowaczyk, Magdalena
Skura, Oliwier
Michalak, Michał
Ratka, Anna

Powiązania:

https://bibliotekanauki.pl/articles/895378.pdf

Data publikacji:

2018-06-30

Wydawca:

Polskie Towarzystwo Farmaceutyczne

Tematy:

health promotion
chronic diseases
pharmacist
community pharmacy
screening services

Opis:

Rising number of chronic diseases worldwide requires improvement of patients’ care system, especially in disease prevention and health promotion. Therefore it is justified to broaden the range of services in community pharmacies in Poland. The aim of this study was to evaluate pharmacists’ opinion about health screenings for chronic diseases in community pharmacies. Research was based on original, anonymous questionnaire administered between July 2016 and March 2017 to pharmacists (n=175; 77.7% women and 22.3% men) practicing in a community pharmacy in Wielkopolska (n=106; 77.4% women and 22.6% men) and Zachodniopomorskie Region (n=69; 78.3% women and 21.7% men). The effect of age and gender on pharmacists’ opinions was evaluated. Among pharmacists who responded, 93.7% agreed that patients don’t have health check-ups when they don’t experience bothersome symptoms of a disease. Almost three fourth of respondents considered implementation of health screening services in pharmacy as valuable as it can have positive influence on development of pharmaceutical care. Younger pharmacists (p=0.019) who collaborate with physicians (p=0.009) were most certain about it. 80,0% of pharmacist, in particular younger one, would offer their patients the screening services (p=0.006). 79,4% pharmacists confirmed that this new service should be reimbursed by National Health Fund. Development of new health screening services in community pharmacies may help to prevent or lower the risk of complications associated with common chronic diseases.

Źródło:

Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 3
0001-6837
2353-5288

Pojawia się w:

Acta Poloniae Pharmaceutica - Drug Research

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 82.

Tytuł:

Inhibition of cell proliferation and induction of apoptosis in K562 human leukemia cells by the derivative (3-NpC) from dihydro-pyranochromenes family

Autorzy:

Rahimi, Roghayeh
Mahdavi, Majid
Pejman, Sina
Zare, Payman
Balalaei, Saeed

Powiązania:

https://bibliotekanauki.pl/articles/1039138.pdf

Data publikacji:

2015

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

apoptosis
chronic myeloid leukaemia
dihydro-pyranochromenes
K562 cells

Opis:

Leukemia is a particular type of cancer characterized by the failure of cell death or disability in differentiation of hematopoietic cells. Chronic myelogenus leukemia (CML) is the most studied kind of this cancer. In this study, anti-cancer effect of dihydro-pyranochromenes derivatives were investigated in the human leukemia K562 cells. These compounds were found to be active cell proliferation inhibitors using MTT assay. Among these compounds, 3-NpC was determined as stronger compound with IC50 value of 100±3.1 µM and was chosen for further studies. Induction of apoptosis was analyzed by AO/EtBr staining, DNA fragmentation assay, Annexin V/PI double staining and cell cycle analysis. Furthermore, Western Blot analysis showed that treatment of the cells with 3-NpC led to up-regulation and activation of caspase-3. The results of this investigation clearly indicated that dihydro-pyranochromenes derivatives induce apoptosis in the K562 cell line. This information signalizes also that these compounds may prepare a new therapeutic approach for the treatment of leukemia.

Źródło:

Acta Biochimica Polonica; 2015, 62, 1; 83-88
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 83.

Tytuł:

Lower-limb ooedema during pregnancy
Obrzęk kończyn dolnych u kobiet w ciąży

Autorzy:

Ochałek, Katarzyna
Frydrych-Szymonik, Aleksandra
Szyguła, Zbigniew

Powiązania:

https://bibliotekanauki.pl/articles/1798651.pdf

Data publikacji:

2016

Wydawca:

Akademia Wychowania Fizycznego im. Bronisława Czecha w Krakowie

Tematy:

Pregnancy
oedema
chronic vein insufficiency
Ciąża
obrzęk
niewydolność żylna

Opis:

Lower-limb oedemas can be the result of abnormalities in the structure and functioning of the lymphatic system, injuries or inflammation, or can be related to cancer and its treatment; however, they are more often one of the basic symptoms accompanying women in the third trimester of pregnancy due to vein insufficiency. The purpose of this overview is to discuss the current knowledge related to risk factors, prevention and treatment of lower-limb oedemas during pregnancy. The risk factors linked to gravidity-related oedema comprise of increased volume of circulating blood, the augmented uterus, increased body mass and changes to hormonal turnover. Vein insufficiency occurs as a result of venous hypertension caused by insufficiency of the muscle pump and valvar regurgitation. Pregnancy, the application of Caesarean section and the postpartum period predispose to deep vein thrombosis (DVT). The basic and unquestionable method applied in the prophylaxis and treatment of abnormalities to the venous-lymphatic system and corresponding complications consists in compression therapy involving compressive bandaging and the use of compression garments. Compression can be applied either individually or in combination with other methods, such as manual lymph drainage, intermittent pump compression and physical or breathing exercises. Based on the scientific evidence and experts’ recommendations, compression is also considered to be an effective solution in the prevention and treatment of deep vein thrombosis and swelling in pregnant women, but further investigation is needed. Ochałek K., Frydrych-Szymonik A., Szyguła Z. Lower-limb oedema during pregnancy. Med Rehabil 2016; 20(4): 17-21. DOI: 10.5604/01.3001.0009.5481
Autorzy przedstawili przypadek 30-letniego mężczyzny, u którego doszło do nagłego zatrzymania krążenia w wyniku porażenia prądem wysokiego napięcia. Od 2. tygodnia po wypadku przeprowadzano rehabilitację w warunkach szpitalnych, mającą na celu utrzymanie zakresu ruchomości w stawach oraz od 6. tygodnia przeprowadzano intensywną rehabilitację w warunkach domowych. Mimo przeprowadzanego leczenia zaobserwowano całkowite ograniczenie ruchomości stawów biodrowych oraz w oparciu o radiogram i projekcję przestrzenną TK zdiagnozowano masywne neurogenne skostnienia heterotopowe (NSH). Przeprowadzono dwa zabiegi mające na celu usunięcie NSH: najpierw z okolicy lewego (15. miesiąc od wypadku), a następnie prawego stawu biodrowego (18. miesiąc od wypadku). Po interwencji zaobserwowano istotny wzrost ruchomości obu stawów biodrowych oraz zmniejszenie dolegliwości bólowych, co w efekcie znacznie poprawiło możliwości funkcjonalne pacjenta. Dodatkowo wprowadzono profi laktykę zapobiegającą nawrotom NSH, która polegała na utrzymaniu zarówno biernego, jak i czynnego zakresu ruchu oraz na stosowaniu zabiegów fi zykoterapeutycznych w postaci głębokiej oscylacji. W badaniu TK, wykonanym w 41. miesiącu po wypadku, uwidoczniono NSH w mniejszym stopniu, aniżeli miało to miejsce pierwotnie.

Źródło:

Medical Rehabilitation; 2016, 20(4); 17-21
1427-9622
1896-3250

Pojawia się w:

Medical Rehabilitation

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 84.

Tytuł:

The needs of persons with chronic health conditions to maintain or return to work 30 years after transformation from socialism into capitalism – a preliminary report from the Polish part of the PATHWAYS project

Autorzy:

Gałaś, Aleksander
Piłat, Aleksandra
Tobiasz–Adamczyk, Beata
Leonardi, Matilde

Powiązania:

https://bibliotekanauki.pl/articles/2116564.pdf

Data publikacji:

2020-06-16

Wydawca:

Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi

Tematy:

Disability
workplace
needs assessment
flexibility
chronic conditions
labor force

Opis:

ObjectivesAn increased burden of chronic diseases in the working age population is observed across high income countries. Persons with chronic diseases (PwCDs) are less likely to maintain or return to work due to several constraints they experience. The purpose of the study was to assess the preferences and needs of PwCDs regarding 6 areas of flexibility at the workplace. It was assessed whether there were any personal characteristics associated with higher or lower expectations and needs.Material and MethodsThis was a part of a large multicenter international project, i.e., the PArticipation To Healthy Workplaces And inclusive Strategies in the Work Sector (PATHWAYS) project, aimed to contribute to the development of innovative approaches to promote professional integration and reintegration of PwCDs into the work sector. In Poland, 59 respondents diagnosed with different chronic diseases were identified through advocacy groups. An on-line survey was conducted to collect information on their needs and expectations. A cluster analysis was performed to reveal some expectation types which differentiated individuals across 6 analyzed domains, along with a multivariable logistic regression to identify some characteristics associated with a special expectation type.ResultsWorkplace facilitator items were generally scored as needed (“rather conductive” and “very conductive” groups identified). The factors positively associated with higher needs in this domain were education, and a hindering type of the disease. Unrestricted working hours were very conductive or indifferent, and were positively associated with education. Legal solutions were more conductive for older people. Medical support, access to training, and supervisors’ knowledge were needed in general, with no associations with the personal characteristics identified.ConclusionsPersons with chronic diseases report several facilitators which are needed for them to maintain or return to work, but they are not satisfied with the existing economy in Poland. These needs should be taken into consideration in the effective policy development.

Źródło:

International Journal of Occupational Medicine and Environmental Health; 2020, 33, 4; 427-444
1232-1087
1896-494X

Pojawia się w:

International Journal of Occupational Medicine and Environmental Health

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 85.

Tytuł:

The role of speech therapy in the rehabilitation of people with chronic cough
Znaczenie terapii logopedycznej w rehabilitacji osób z przewlekłym kaszlem

Autorzy:

Watras, Anna
Jamróz, Barbara
Czernicki, Tomasz
Walczak, Joanna
Milewska, Magdalena
Arcimowicz, Magdalena
Niemczyk, Kazimierz

Powiązania:

https://bibliotekanauki.pl/articles/1399703.pdf

Data publikacji:

2018-11-23

Wydawca:

Index Copernicus International

Tematy:

chronic cough
MTD
SPL therapy
przewlekły kaszel
terapia logopedyczna

Opis:

Introduction. Cough is the most common symptom of respiratory diseases. It has a significant impact on the quality of life of patients. Aim. Examination and comparison of cough intensity, symptoms associated with cough, head and neck muscle’s tonus, breathing type and maximum phonation time in patients with chronic cough before and after speech therapy. Material and methods. The study comprised 10 patients, including 8 women and 2 men from 30 to 73 years of age. All participants completed The Visual Analogue Scale (VAS), Reflux Symptoms Index (RSI), Voice Tract Discomfort (VTD), Voice Handicap Index (VHI). Additionally, the breathing track, muscle tension within the head and neck, maximum time of phonation were evaluated. Results. The results Visual Analogue Scale, Voice Handicap Index and the maximum phonation time after speech therapy were statistically significant (p <0.05) lower compared to the pre-therapy results. Not all results of the Reflux Symptoms Index and Voice Tract Discomfort were consistent with the normal distribution (p> 0.05) Conclusions. Speech therapy therapy has a significant impact on the severity of chronic cough, symptoms associated with cough, the normalization of head muscle tension, improvement of the breathing track and the elongation of the maximum time of phonation. It is the future direction in the therapy of patients with chronic cough.
Cel pracy: Ocena wpływu terapii logopedycznej na jakość głosu u pacjentów z jednostronnym porażeniem krtani. Materiał i Metody: Badaniem objęto 11 pacjentów, w tym 8 kobiet i 3 mężczyzn w wieku od 16 do 72 lat, diagnozowanych z powodu problemów z głosem w Klinice Otolaryngologii i Poradni Foniatrycznej SP CSK w latach 2017‒2018. Każda osoba została poproszona o wypełnienie kwestionariuszy: skala samooceny niepełnosprawności głosu (VHI), skala jakości życia zależnej od głosu (VRQoL), skala dyskomfortu traktu głosowego (VTD). Powyższe kwestionariusze były wypełniane przez badanych dwukrotnie, przed rozpoczęciem rehabilitacji głosu oraz po niej. Ponadto u każdego z pacjentów została dwukrotnie wykonana analiza akustyczna głosu, ocena maksymalnego czasu fonacji oraz toru oddechowego. Każdy z chorych odbył rehabilitację głosu składającą się z cyklu 10 spotkań. Wyniki: Analiza statystyczna wyników maksymalnego czasu fonacji, skali samooceny niepełnosprawności głosu, skali jakości życia zależnej od głosu, skali dyskomfortu traktu głosowego analizy akustycznej głosu wykazała istotne statystycznie różnice w wynikach przed rehabilitacją i po niej (p<0,005). Ponadto u większości pacjentów zaobserwowano poprawę toru oddechowego. Wnioski: Terapia logopedyczna istotnie wpływa na jakość głosu pacjentów z jednostronnym porażeniem nerwu krtaniowego.

Źródło:

Polski Przegląd Otorynolaryngologiczny; 2018, 7, 4; 1-7
2084-5308
2300-7338

Pojawia się w:

Polski Przegląd Otorynolaryngologiczny

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 86.

Tytuł:

Influence of nasal mucosa irritants on the occurrence of chronic rhinosinusitis without /and with polyps

Autorzy:

Olszewska, Aleksandra
Niewiadomski, Piotr
Olszewski, Jurek

Powiązania:

https://bibliotekanauki.pl/articles/1397254.pdf

Data publikacji:

2021

Wydawca:

Index Copernicus International

Tematy:

chronic rhinosinusitis with/without nasal polyps
irritants
nasal mucosa

Opis:

Introduction: The aim of the study was to assess the effect of nasal mucosa irritants on the occurrence of chronic rhinosinusitis without/and with nasal polyps. Material and methods: The study involved 100 adult participants, including 39 women and 61 men, aged 21–68, diagnosed and treated at the Department of Otolaryngology, ENT Oncology, Audiology and Phoniatrics at the University Clinical Hospital WAM in Łódź. Based on the otorhinolaryngological and imaging (CT) tests they were divided into two groups: I – 50 patients, including 23 women and 27 men, aged 21–64 – with chronic rhinosinusitis without nasal polyps, II – 50 patients, including 16 women and 34 men, aged 22–68 – with chronic rhinosinusitis with nasal polyps. The control group consisted of 50 people (group III), including 25 women and 25 men, aged 18–30, students of the Faculty of Military Medicine at the Medical University of Lodz. All respondents completed a prepared questionnaire consisting of 17 questions addressed in the form of an anonymous interview among patients treated in the Department of Otolaryngology, ENT Oncology, Audiology and Phoniatrics. Results: The conducted surveys indicate the impact of the following factors in pathogenesis of chronic rhinosinusitis without/ with nasal polyps: exogenous factors (viruses, bacteria, fungi, drugs, injuries, toxic substances, environmental pollution), general endogenous factors (allergy, hypersensitivity to acetylsalicylic acid and its derivatives, hormonal disorders, supraesophageal reflux disease, granulation disease, immunity disorders, local endogenous factors. Conclusions: In the examined material, patients with chronic rhinosinusitis without/and nasal polyps in most cases are in the age range 51–60 years and over 60 years, they most often live in large cities over 250 thousand inhabitants, suffer from allergic rhinorhinitis in 38.0% in group I and 36.0% in group II, rapid temperature changes and dry air have a negative impact on comfort of breathing. The conducted surveys confirm that the cause of chronic rhinosinusitis with polyps is multifactorial, but a significant factor affecting typical tissue remodeling in this disease is long-term breathing of polluted atmospheric air.

Źródło:

Polish Journal of Otolaryngology; 2021, 75, 1; 36-44
0030-6657
2300-8423

Pojawia się w:

Polish Journal of Otolaryngology

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 87.

Tytuł:

Functional endoscopic sinus surgery (FESS) in unilateral sinus disease

Autorzy:

Mielcarek-Kuchta, Daniela
Simon, Karolina
Kondratowicz, Dawid
Łukomska, Zofia
Rybak-Korytowska, Aleksandra

Powiązania:

https://bibliotekanauki.pl/articles/1398482.pdf

Data publikacji:

2017

Wydawca:

Index Copernicus International

Tematy:

unilateral sinus disease
FESS
chronic rhinosinusitis
inverted papilloma
mycosis

Opis:

Background: Unilateral sinus disease (USD) occurs in 23 % of all cases. It is believed that it is mainly associated with cancer development. Retrospective data from large rhinological centers show that the most common USD is chronic rhinosinusitis (CRS), followed by mycosis, inverted papilloma and finally cancer, but only in a small percent of cases. The aim of the study: The analysis of USD in the group of patients who underwent FESS at the secondary referral center. Material and Method: The retrospective study of patients treated for USD in the Department of Otolaryngology in the Provincial Hospital in Poznan between June 2014 and June 2016. The analysis includes age, sex, the localization of lesions, histopathological and microbiological results, an extension of the surgery and treatment results. Results: Over the analyzed period of time, 415 FESS for chronic sinusitis were performed. In this group, 83 patients underwent surgery for USD. There were 35 women and 48 men.CRS was found in 48 cases, mycosis in nine cases, 12 patients were operated for non-malignant tumors, such as inverted papilloma (9), osteoma (2) and fibrosis tumor(1); seven patients had a choanal polyp and two of them had a foreign body in maxillary sinus – a tooth root lying loose. Four patients were diagnosed with a hypoplastic maxillary sinus and one patient suffered from frontal sinus pyocele. One side endoscopic opening of all sinuses was performed in the group with CRS, endoscopic medial maxillectomy was conducted in patients with inverted papilloma, and an isolated opening of the affected sinus was performed in the cases with mycosis. Conclusions: USD must be always suspected of malignant degeneration until proven otherwise. Endoscopic sinus surgery with the use of angled scope allows for the removal of even very extensive lesions. In our opinion, the extent of operation is determined by the nature of pathology. While extensive surgery is recommended in patients with inverted papilloma, a limited procedure should be performed in those with isolated mycosis.

Źródło:

Polish Journal of Otolaryngology; 2017, 71, 5; 29-35
0030-6657
2300-8423

Pojawia się w:

Polish Journal of Otolaryngology

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 88.

Tytuł:

Zásady výživy u pacientů s chronickou renální insuficiencí

Autorzy:

Gulášová, Ivica
Görnerová, Lenka
Babečka, Jozef

Powiązania:

https://bibliotekanauki.pl/articles/2130390.pdf

Data publikacji:

2019

Wydawca:

Instytut Studiów Międzynarodowych i Edukacji Humanum

Tematy:

chronic renal failure
diet therapy
low-protein diet
uremia

Opis:

New researches confirm that nutrition, along with modern therapeutic procedures, is of great im- portance for the optimal treatment of chronic renal insufficiency. Necessary is the reduction in total protein intake based on the level of renal function. Low protein diets can reduce uremic symptoms in non-dialysis patients with chronic renal failure and can slow down the progression of renal insuffi- ciency in patients with chronic renal insufficiency. At present, protein-restricted diets are used in con- junction with a nutritional therapist. Long-term administration of low-protein diet is contraindicated in patients with end-stage chronic renal failure, with uremic complications, with severe signs of urine retention and electrolytes and with poor compliance with low-protein diet. A low-protein diet with ketoanalogs can not only stabilize renal function but also has a beneficial effect on blood pressure, proteinuria, lipid profile and calcium phosphate metabolism. Depending on the size of diuresis, blood pressure, sodium and fluid balance and potassium levels, the maximal intake of fluids, sodium and potassium should be considered.

Źródło:

Humanum. Międzynarodowe Studia Społeczno-Humanistyczne; 2019, 2 (33); 83-90
1898-8431

Pojawia się w:

Humanum. Międzynarodowe Studia Społeczno-Humanistyczne

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 89.

Tytuł:

Multiple sclerosis and pregnancy – treatment considerations

Autorzy:

Kamieniak, M.P.
Wolanin, N.
Jarosz, P.
Kobialka, I.
Kosmider, K.
Petit, V.
Rejdak, K.

Powiązania:

https://bibliotekanauki.pl/articles/2098207.pdf

Data publikacji:

2020

Wydawca:

Instytut Medycyny Wsi

Tematy:

multiple sclerosis
chronic inflammatory disease
pregnancy
neurology
gynaecology
treatment

Opis:

Multiple sclerosis is a chronic inflammatory disease which, due to the destruction of the fibres of the central nervous system in the process of demyelination, leads to numerous neurological symptoms and progressive disability. The disease is autoimmune, which means that myelin is destroyed by the patient’s own cells, caused by improper functionong and regulation of the immune system. Multiple sclerosis affects more and more people and is therefore a significant clinical problem which, to a large Entent, affects women, especially in childbearing age This presents a big challenge for carrying out pregnancy while continuing the therapy, ensuring the safety of the foetus and simultaneously achieving the best possible therapeutic effect. The decision whether the therapy should be continued or whether it should be eliminatedis usually made according to assessment of the possible gains and losse. Despite the lack of clear indications, there are many studies proving the relative safety of the use of individual but not all the drugs during pregnancy. Pregnancy, however, has a fairly good impact on the development of multiple sclerosis, and that safety considerations, especially those concerning the growing foetus, force a decision to change or completely suspend the therapy. In-depth research on the already available and emerging therapeutic pathways in multiple sclerosis bring hope for increasingly better results in the future in the treatment of pregnant patients with multiple sclerosis.

Źródło:

Journal of Pre-Clinical and Clinical Research; 2020, 14, 4; 126-129
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 90.

Tytuł:

Adherence to treatment among chronically ill ambulatory patients

Autorzy:

Bojanowska, Agnieszka
Zatorski, Mateusz
Gazdowska, Jolanta
Durlik, Magdalena

Powiązania:

https://bibliotekanauki.pl/articles/2128251.pdf

Data publikacji:

2017

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

adherence
chronic illness
Information-Motivation-Behavioural Skills model
treatment

Opis:

According to Information-Motivation-Behavioural Skills model (IMB), accurate Information, strong Motivation and adequate Behavioural skills are prerequisites of treatment adherence. This model has been verified among chronically ills patients, usually suffering from one particular disorder. No studies report how the model fits data from a more diverse group. The aim of the study was to analyze adherence and its barriers in a group of three hundred patients suffering from various, common chronic disorders. They filled out IMB and Adherence Questionnaire. Information and Motivation correlated moderately (.35). Behavioural Skills was the strongest predictor of adherence (.24). An additional relationship was found: Information and Motivation interacted and the role of either of these dimensions vanished if the indices of the other were high enough. The relationships between IMB dimensions and adherence were confirmed in a varied clinical sample. Behavioural skills must be considered when working with non-adherent patients, as they are the strongest predictor of adherence. Other interventions may be limited to either Information or Motivation only if there is a chance of raising one of them to extreme levels. This may be useful with special cases, when increasing both is problematic.

Źródło:

Polish Psychological Bulletin; 2017, 3; 380-387
0079-2993

Pojawia się w:

Polish Psychological Bulletin

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 91.

Tytuł:

Role of sulfide anion in the development of chronic alcoholic hepatitis under the conditions of modulation of adenosine monophosphate kinase – a correlational study

Autorzy:

Mykytenko, Andrii
Akimov, Oleh
Shevchenko, Oleksandr
Neporada, Karine

Powiązania:

https://bibliotekanauki.pl/articles/29519432.pdf

Data publikacji:

2023-09-30

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

AMPK
chronic alcohol hepatitis
doxorubicin
liver
phenformin
sulfide anion

Opis:

Introduction and aim. Hydrogen sulfide (H₂S) has attracted the attention of researchers as a novel signaling molecule that affects vascular metabolism, immune function, stress and inflammation. It plays an important role in pathophysiological disorders under the conditions of the development of obesity, diabetes, non-alcoholic fatty liver disease and cardiovascular diseases. The purpose of this work is to establish correlation ratios of H₂S concentration with markers of oxidative-nitrosative stress and extracellular matrix metabolism of the liver during chronic alcoholic hepatitis modeling and AMPK modulation by phenformin and doxorubicin. Material and methods. The experiments were performed on 36 white, sexually mature male Wistar rats, weighing 180-220 g. Alcoholic hepatitis was modelled by alcohol administration, on the background of alcoholic hepatitis animals received phenformin orally at a dose of 10 mg/kg or doxorubicin at a dose of 1.25 mg/kg intraperitoneally. Statistical processing of the results of biochemical studies was carried out using the non-parametric method of Spearman to determine correlations. Results. H₂S during alcoholic hepatitis inversely proportionally strongly correlates with the concentration of nitrites, oxyproline and arginase activity. Phenformin administration during alcoholic hepatitis leads to formation of inversely proportionally strongly correlation of H₂S with the production of superoxide anion radical, the concentration of malondialdehyde, activities of constitutive NO-synthases, nitrite reductases, nitrate reductases, and arginase. Doxorubicin administration during alcoholic hepatitis leads to formation of directly proportional strongly correlation of H₂S with the activity of constitutive NO-synthases, nitrite reductases, nitrate reductases. Conclusion. Administration of phenformin or doxorubicin expands correlations between H₂S and indicators of oxidative-nitrosative stress.

Źródło:

European Journal of Clinical and Experimental Medicine; 2023, 3; 567-575
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 92.

Tytuł:

Prevalence, prescription patterns, and quality of life of anaemia in adults with chronic renal disease

Autorzy:

Sandeep, Akkam
Elumalai, Karthikeyan
Williams, Helen
Salkapuram, Sunilkumar
Anandakumar, Shanmugam
Srinivasan, Sivaneswari

Powiązania:

https://bibliotekanauki.pl/articles/29520467.pdf

Data publikacji:

2023

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

anaemia
chronic kidney disease
prescribing pattern
quality of life

Opis:

Introduction and aim. Anaemia is a chronic kidney disease (CKD) condition characterised by a decline in glomerular filtration rate (GFR) and impaired kidney function. The aim of this study was to assess the prevalence, prescribing patterns, and quality of life of anaemia in patients with chronic renal disease who were adults (>18 years of age) at a tertiary care hospital. Material and methods. Data on demographic characteristics, laboratory results, medication prescriptions, and quality of life assessments were collected. Statistical tests were performed to determine associations between anaemia prevalence and factors like age, gender, and CKD stage. The study included 132 patients, with a gender distribution of 89 men and 43 women. Results. The most frequently prescribed drugs are epoetin (15.06%), multivitamins (14.82%), iron (10.65%), folic acid (10.22%), calcium carbonate (8.17%), calcitriol (5.6%), and omeprazole (4.22%). The cardiovascular system, blood disorders, and blood-producing organs come after the gastrointestinal tract and metabolism in the first anatomical level of the ATC classification. Conclusion. It suggests hospital audits and recommendations for improved prescription practices. Further investigation into anaemia causes and drug class appropriateness is needed, and implementing improvements could potentially improve health outcomes

Źródło:

European Journal of Clinical and Experimental Medicine; 2023, 4; 785-792
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 93.

Tytuł:

The 30-day mortality predictor role of c-reactive protein/albumin ratio in critically ill COPD patients

Autorzy:

Cırık, Mustafa Özgür
Baldemir, Ramazan
Doğanay, Güler Eraslan
Ünver, Meriç
Avcı, Sema

Powiązania:

https://bibliotekanauki.pl/articles/29432111.pdf

Data publikacji:

2020-12

Wydawca:

Towarzystwo Pomocy Doraźnej

Tematy:

C-reactive protein
albumin
chronic obstructive pulmonary disease
mortality

Opis:

INTRODUCTION: Chronic Obstructive Pulmonary Disease (COPD) is a progressive disease that develops due to inflammation in the airways. The aim of this study is to demonstrate the effectiveness of c-reactive protein/albumin ratio (CAR) as a 30-day mortality indicator in COPD patients admitted to ICU. MATERIAL AND METHODS: A total of 235 COPD patients with available data between January 2018 and December 2018 were included in this retrospective cohort study. Demographics, APACHE II, Charlson comorbidity index (CCI), SOFA score, CAR and outcomes were evaluated. RESULTS: 87 (37%) of the cases were female and 148 (63%) were male. Their ages ranged from 26 to 95 years, with an average of 70.9± 11.4. The non-survivors had significantly higher APACHE II, CCI, SOFA score, procalcitonin, creatinine, mechanical ventilation (MV) time, WBC, CRP and CAR compared to the survivors (p˂0.05). Albumin and prealbumin were significantly lower (p˂0.05) in non-survivors. In the univariate model; age, sepsis, inotropic support, APACHE II score, CCI, SOFA, procalcitonin, creatinine, MV time, WBC, CRP, albumin, prealbumin and CAR were observed to be significantly effective (p˂0.05) in predicting 30-day mortality. In the multivariate reduced model; inotropic support, SOFA, WBC and prealbumin value exhibited significant independent (p<0.05) effectiveness in predicting 30-day mortality. Albumin, CRP, CAR, APACHE II, SOFA and CCI value were observed to be significant in predicting mortality (p=0.000). CONCLUSIONS: In the study, the predictive power of APACHE II score, CCI, SOFA score, albumin and prealbumin values alone was found to be significantly higher than that of the CAR.

Źródło:

Critical Care Innovations; 2020, 3, 4; 1-12
2545-2533

Pojawia się w:

Critical Care Innovations

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 94.

Tytuł:

Exhaled nitric oxide in smokers and former smokers with chronic obstructive pulmonary disease

Autorzy:

Galiniak, S.
Aebisher, D.
Rachel, M.

Powiązania:

https://bibliotekanauki.pl/articles/2087917.pdf

Data publikacji:

2020

Wydawca:

Uniwersytet Opolski. Instytut Nauk o Zdrowiu

Tematy:

nitric oxide
smoking
respiratory diseases
chronic obstructive pulmonary disease

Opis:

Background: Measurement of fractional exhaled nitric oxide (FeNO) is a useful technique for detection of eosinophilic airway inflammation and assessment of efficiency of corticosteroid treatment in patents with respiratory disease. Generally studies agree that measurement of FeNO is a useful non-invasive biomarker in patients with chronic obstructive pulmonary disease (COPD), however, there are reports that do not confirm such a relationship between FeNO and COPD. Aim of the study: The main objective of this study was to investigate FeNO levels in Polish patients with COPD compared to healthy controls. As a secondary objective, we assessed the influence of smoking on FeNO levels in healthy patients, and patients with COPD. Material and methods: FeNO concentration was measured using an electrochemical analyzer in healthy nonsmokers (n=21), healthy smokers (n=25), and former smokers with COPD (n=30) and smokers with COPD (n=38). General characteristics, hematological variables and serum biochemical parameters were also obtained and analyzed using the Kruskal-Wallis test. Results: FeNO measurement revealed significantly reduced NO levels in healthy smokers compared to healthy non-smokers, former smokers with COPD and smokers with COPD (median [range]: 14 [6–17] vs. 21 [15–29], 25 [15–53], and 19 [11–32] ppb, respectively, p<0.001). Moreover, we found increased FeNO levels in ex-smokers with COPD compared with smokers with COPD (p<0.05). No associations between FeNO and other analyzed parameters were found. Conclusions: Levels of FeNO, measured by with an electrochemical analyzer, were elevated among patients with COPD compared to healthy non-smoking controls. Moreover, our study confirms that smoking results in a reduction in FeNO concentration in both healthy patients and patients with COPD.

Źródło:

Medical Science Pulse; 2020, 14, 2; 36-43
2544-1558
2544-1620

Pojawia się w:

Medical Science Pulse

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 95.

Tytuł:

Wpływ stresu przewlekłego na rozwój nadciśnienia tętniczego
The influence of chronic stress on development of hypertension

Autorzy:

Jodłowska, Emilia
Juszczak, Marlena

Powiązania:

https://bibliotekanauki.pl/articles/1032728.pdf

Data publikacji:

2013

Wydawca:

Łódzkie Towarzystwo Naukowe

Tematy:

stres przewlekły
glukokortykosteroidy
nadciśnienie tętnicze
chronic stress
glucocorticoids
hypertension

Opis:

Chronic stress is one of the factors which increase the probability of arterial hypertension development. The chronic stimulation of central and peripheral components of the stress system affects this process directly and indirectly by, among others, the evolution of visceral obesity. The hypothalamus-pituitaryadrenal gland axis (HPA) activity and the sympathetic nervous system stimulation play a significant role in the pathogenesis of arterial hypertension. Glucocorticoids are terminal effectors of the HPA axis and they are responsible for the initiation of many pathomechanisms leading to arterial hypertension development. These hormones may adversely affect the lipid and carbohydrate metabolism and the endocrine glands activity. The excessive secretion of glucocorticoids and the chronic hyperactivity of the HPA axis conduce the visceral fat accumulation. Adipose tissue is metabolically active and significantly affects hyperinsulinemia and insulin resistance by producing adipokines. The hypertensive effect induced by glucocorticoids action results, among others, from the inhibition of nitric oxide synthesis and impaired action of the isoform 2 of the 11-β-hydroxysteroid dehydrogenase. On the other hand, the stimulation of the sympathetic nervous system during chronic stress results in disturbances in the central regulation of arterial pressure, hyperactivity of the renin–angiotensin-aldosterone system and augmentation of the vasoconstrictor substances production. Chronic stress leads to endothelial dysfunction, remodelling of the blood vessels and their hypertrophy, growing of vascular resistance, inflammatory and prothrombotic processes in blood vessels. The paper discusses the major pathomechanisms which are induced by chronic stress and may potentially lead to development of hypertension.
Stres przewlekły jest jednym z czynników zwiększających prawdopodobieństwo rozwoju nadciśnienia tętniczego. Chroniczne pobudzenie ośrodkowych i obwodowych składowych reakcji stresowej wpływa na rozwój nadciśnienia tętniczego bezpośrednio oraz pośrednio, między innymi, poprzez rozwój otyłości trzewnej. W patogenezie nadciśnienia tętniczego uwarunkowanego stresem przewlekłym istotne znaczenie ma aktywacja osi podwzgórze-przysadka-kora nadnerczy (PPKN) i pobudzenie układu współczulnego. Glukokortykosteroidy, jako końcowy efektor osi PPKN, inicjują szereg patomechanizmów sprzyjających rozwojowi nadciśnienia tętniczego - wywierają niekorzystny wpływ na profil lipidowy, gospodarkę węglowodanową oraz czynność gruczołów wydzielania wewnętrznego. Nadmierne wydzielanie glukokortykosteroidów i chroniczna aktywacja osi PPKN sprzyjają akumulacji tkanki tłuszczowej w obrębie jamy brzusznej. Tkanka tłuszczowa posiada aktywność metaboliczną i poprzez produkcję adipokin istotnie przyczynia się do rozwoju hiperinsulinemii oraz insulinooporności. Efekt hipertensyjny wywołany działaniem kortyzolu jest konsekwencją uwrażliwienia mięśniówki gładkiej naczyń na wewnątrzpochodne czynniki presyjne, zwiększenia zatrzymywania sodu i wody w ustroju (co prowadzi do hiperwolemii), zwiększenia lepkości krwi, hipercholesterolemii i dyslipoproteinemii oraz nasilonej trombocytozy, która sprzyja powstawaniu zakrzepów. Istotne znaczenie ma tu zahamowanie syntezy tlenku azotu i upośledzenie czynności izoformy 2 dehydrogenazy 11-β-hydroksysteroidowej. Z drugiej strony, chroniczna aktywacja układu współczulnego w stresie przewlekłym prowadzi do zaburzenia ośrodkowej regulacji ciśnienia tętniczego, a także do pobudzenia układu renina-angiotensyna-aldosteron i nasilenia syntezy czynników naczyniokurczących. Stres przewlekły sprzyja uszkodzeniu śródbłonka naczyniowego, przebudowie ściany naczyń krwionośnych i zwiększeniu oporu obwodowego oraz aktywacji procesów zapalnych i prozakrzepowych w naczyniach krwionośnych, a także przerostowi lewej komory serca. Celem niniejszego opracowania jest przedstawienie patomechanizmów, które indukowane są w warunkach stresu przewlekłego i mogą potencjalnie prowadzić do rozwoju pierwotnego nadciśnienia tętniczego.

Źródło:

Folia Medica Lodziensia; 2013, 40, 1; 53-77
0071-6731

Pojawia się w:

Folia Medica Lodziensia

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 96.

Tytuł:

Dietary supplement use among patients with chronic kidney disease

Autorzy:

Jakimowicz-Tylicka, Marzena
Chmielewski, Michał
Kuźmiuk-Glembin, Izabella
Skonieczny, Piotr
Dijakiewicz, Grażyna
Zdrojewska, Grażyna
Rutkowski, Bolesław
Tylicki, Leszek
Dębska Ślizień, Alicja

Powiązania:

https://bibliotekanauki.pl/articles/1038410.pdf

Data publikacji:

2018

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

dietary supplements
vitamins
minerals
chronic kidney disease
dialysis
toxicity

Opis:

Background. Dietary supplements (DS) are available over the counter, but patients with impaired renal function are specifically at risk for toxicity when consuming certain DS. The aim of this study was to evaluate the prevalence and characteristics of DS use in patients with chronic kidney disease (CKD). Material and methods. A cross-sectional, controlled DS use survey (22 questions) was conducted among 180 CKD patients (stage 1-5, dialysis, kidney transplant), with 60 patients without CKD serving as controls. Results. DS use did not differ significantly between subjects with and without CKD, unless the CKD patients were on dialysis. In the CKD group, 20% admitted to use DS regularly and 22% did not take the mat all. In the controls, DS consumption was 17% and 13%, respectively (NS). The DS use was higher among women ascompared to men (89% vs. 70%; p < 0.005), and people living in cities versus those living in the country side (81% vs. 63%; p < 0.05). DS most commonly used were: vitamins, minerals, and herbs. Major indications for DS use included: musculoskeletal issues, general health improvement and prevention of urinary tract infections. Subgroup analyses revealed that dialysis patients were characterized by a significantly higher DS use in comparison to CKD stage 1-5 subjects and renal transplant recipients. The decision to introduce DS was made by the physician in 54% of cases; by a pharmacist in 9% of cases, and by the patients themselves in 37%. Only 21% of patients with CKD, and 27% of subjects without CKD, declared knowledge of any possible side-effects associated with DS (NS). Conclusions. The use of DS among patients with CKD is similar to patients without CKD, with the exception of those on dialysis. Vitamins and minerals were the most commonly reported DS consumed. The knowledge on potential side-effectof DS was limited to approximately one-fourth of those surveyed.

Źródło:

Acta Biochimica Polonica; 2018, 65, 2; 319-324
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 97.

Tytuł:

Diagnosis and treatment difficulties in 18-year-old male patient with hereditary hemochromatosis, chronic hepatitis B, Gilbert syndrome and ulcerative colitis

Autorzy:

Sikorska, Katarzyna
Liberek, Anna
Romanowski, Tomasz
Szlagatys-Sidorkiewicz, Agnieszka
Landowski, Piotr
Bielawski, Krzysztof

Powiązania:

https://bibliotekanauki.pl/articles/1039929.pdf

Data publikacji:

2011

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

hereditary hemochromatosis
ulcerative colitis
chronic hepatitis B
Glibert syndrome

Opis:

Among possible causes of chronic hepatitis in adolescents most common are infections, autoimmune disorders and metabolic diseases. Thus, diagnostic procedures should be multidirectional. This study reports diagnosis and treatment difficulties in an 18-year-old male patient with hereditary hemochromatosis (HH), ulcerative colitis (UC), chronic hepatitis B (CHB) and Gilbert syndrome. The presented case illustrates problems in diagnostics related to the presence of numerous disease conditions in one patient. It should be taken into consideration that these diseases coexisting in one patient can mutually affect their symptoms creating specific diagnostic difficulties.

Źródło:

Acta Biochimica Polonica; 2011, 58, 2; 251-254
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 98.

Tytuł:

Selenium supplementation to chronic kidney disease patients on hemodialysis does not induce the synthesis of plasma glutathione peroxidase

Autorzy:

Zachara, Bronislaw
Gromadzinska, Jolanta
Zbrog, Zbigniew
Swiech, Rafal
Wasowicz, Wojciech
Twardowska, Ewa
Jablonska, Ewa
Sobala, Wojciech

Powiązania:

https://bibliotekanauki.pl/articles/1040656.pdf

Data publikacji:

2009

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

hemodialysis
selenium supplementation
glutathione peroxidase
chronic kidney disease
plasma

Opis:

Background: Numerous authors have shown that selenium (Se) concentration and glutathione peroxidase (GSH-Px) activity in plasma of chronic kidney disease (CKD) patients are lower than in healthy subjects, but there are only few publications on the level of GSH-Px protein in those patients and no reports on the effect of Se supplementation to HD patients on the level of this enzyme. Subjects and Methods: Se concentration and GSH-Px protein level in plasma were measured in a group of 30 CKD patients on hemodialysis (HD) supplemented with 200 µg Se/day for 3 months, and 28 patients on HD administered with placebo. Se concentration was measured by graphite furnace atomic absorption spectrometry and plasma GSH-Px protein level by the sandwich ELISA method using polyclonal antibody specific for human plasma GSH-Px. Results: Se concentration in patients on placebo did not change throughout the 3-month study period, but increased significantly in Se supplemented group. Se supplementation to CKD patients on HD had no effect on the level of GSH-Px protein. Conclusions: The lack of GSH-Px protein in CKD patients on HD is not linked to Se deficiency since the level of this element increased after Se supplementation while enzyme protein level did not change. The damaged kidney of HD patients is unable to synthesize GSH-Px, even after induction with selenium.

Źródło:

Acta Biochimica Polonica; 2009, 56, 1; 183-187
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 99.

Tytuł:

Differentiated Diagnostics and Multimodal Therapy of Neuropathic Pain
Differenzierte Diagnostik und multimodale Therapie neuropathischer Schmerzen

Autorzy:

F. MASUHR, Karl

Powiązania:

https://bibliotekanauki.pl/articles/1033768.pdf

Data publikacji:

2014

Wydawca:

Zakład Opieki Zdrowotnej Ośrodek Umea Shinoda-Kuracejo

Tematy:

chronic pain
multimodal therapy
neuropathic pain diseases
phantom pain

Opis:

Whereas acute pain acts as a warning sign, neuropathic pain loses this protective attribute and develops a self–sustaining chronic course. Almost 33 % of the general population report chronic pain and at least 3,3 % neuropathic pain, in Germany ≤ 5 million people. The prevalence is higher in women and increases with age. Neuropathic pain is defined as a direct consequence of a lesion or disease affecting the somatosensory system either at peripheral or central level. Spontaneously occurring dysesthesias, particularly burning pain and repetitive stimulus–triggered neuralgias such as classical trigeminal neuralgia are typical clinical features. Neuropathic pain is frequently found in patients with radiculopathy, nerve compression syndrome and polyneuropathy. The complex regional pain syndrome (CRPS) is associated with abnormal sudomotor, vasomotor and trophic findings as well as psychosomatic symptoms. Frequent reasons for neuropathic pain of CNS origin are cerebral ischemia and traumatic injuries of the spinal cord with phantom pain. Clinical examination, including accurate sensory examination and Quantitative sensory testing (QST), is the basis of pain diagnosis and therapy. It is important to distinguish neuropathic pain from other chronic pain syndromes: Multimodal therapy differs from treatment of nociceptive pain (for example, in most cases of arthropathy), when the nervous system is intact. Drugs of choice are antidepressants and antiepileptics with analgesic properties.

Źródło:

Medicina Internacia Revuo; 2014, 26, 103; 97-105
0465-5435

Pojawia się w:

Medicina Internacia Revuo

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 100.

Tytuł:

Selenium, glutathione and glutathione peroxidases in blood of patients with chronic liver diseases.

Autorzy:

Czuczejko, Jolanta
Zachara, Bronisław
Staubach-Topczewska, Ewa
Halota, Waldemar
Kędziora, Józef

Powiązania:

https://bibliotekanauki.pl/articles/1043405.pdf

Data publikacji:

2003

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

selenium
glutathione peroxidase
chronic liver disease
glutathione
oxidative stress

Opis:

Disturbances in the antioxidant system could play a role in pathogenesis of chronic liver disease. The aim of our study was to evaluate the levels/activities of antioxidants in blood of patients with chronic liver disease. We estimated selenium and glutathione concentrations and glutathione peroxidase activities in blood of 59 patients with chronic hepatitis B or C virus infection (group 1) and 64 patients with alcoholic, autoimmune or cryptogenic chronic liver disease (group 2). The results were compared with 50 healthy controls. Whole blood and plasma selenium and red cell glutathione concentrations were significantly lower in the patients compared with the controls. Red cell glutathione peroxidase activity was slightly reduced in both subgroups of group 1 and in group 2 with normal alanine aminotransferase values. Plasma glutathione peroxidase activity was slightly but significantly higher in patients with elevated aminotransferase values. The findings suggest that disturbances in antioxidant parameters in blood of patients with chronic liver disease may be the cause of the peroxidative damage of cells.

Źródło:

Acta Biochimica Polonica; 2003, 50, 4; 1147-1154
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

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