Skocz do pozycji: 1.

Tytuł:

The influence of therapeutic education on diabetes-related distress and therapeutic adherence among patients with type 2 diabetes in Tetouan, Morocco

Autorzy:

Belhaj, Hajar
Barouaca, Hassan
Oudghiri, Dia Eddine
Lamiri, Abderrahmane
Mostakim, Mohammed
Timihiri, Abderrahim
Ahyayauch, Hasna
Saoud, Younes

Powiązania:

https://bibliotekanauki.pl/articles/40495585.pdf

Data publikacji:

2024-03-30

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

diabetes-related distress
therapeutic education
type 2 diabetes

Opis:

Introduction and aim. Diabetes-related distress is a prevalent issue that affects many patients, leading to challenges in adhering to treatment plans and lifestyle modifications. By implementing therapeutic education programs, healthcare providers seek to enhance patients’ understanding of their condition, coping mechanisms, and treatment adherence. This study aims to explore the impact of therapeutic education on diabetes-related distress and therapeutic adherence among individuals diagnosed with type 2 diabetes. Material and methods. This quasi-experimental study involved 40 patients with type 2 diabetes receiving therapeutic education during 6 Months from March 24 to September 30, 2022. Diabetes-related distress and adherence were assessed before and after the intervention using the Diabetes Distress Scale (DDS-17) and glycated hemoglobin (HbA1c) levels. Results. Wilcoxon signed rank tests revealed statistically significant improvements for all measures after the intervention. Patients showed improved DDS-17 scores (p<0.001) across all dimensions, and lower HbA1c levels (p<0.001). Pre- and post-intervention mean difference across all measures show that the greatest improvements were seen in emotional distress (1.37) and treatment-related distress (1.2). Conclusion. Therapeutic education had a positive impact on therapeutic adherence and diabetes-related distress. It should be an integral part of type 2 diabetes care protocols in Morocco.

Źródło:

European Journal of Clinical and Experimental Medicine; 2024, 22, 1; 140-146
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 2.

Tytuł:

Prevalence of depression in Indian patients with type 2 diabetes mellitus and/or hypertension: DEPTH Study

Autorzy:

Lalwani, Raj Kumar
Shah, Jayesh Dashrathlal
Chatterjea, Tapas
Nadakuduru, Papa Rao
Erande, Suhas

Powiązania:

https://bibliotekanauki.pl/articles/454720.pdf

Data publikacji:

2019

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

comorbidity
diabetes
depression
hypertension prevalence
type 2 diabetes mellitus

Opis:

ABSTRACT Introduction. Depression, a common psychiatric mood disorder, is a leading cause of disability and a significant contributor to the overall global burden of disease. Aim. To determine the prevalence of depression in patients with controlled and uncontrolled type-2 diabetes mellitus (T2DM) and/or hypertension (HTN) in India. The association of depression with socio-demographic profile and clinical risk factors was also assessed. Material and methods. In this cross-sectional epidemiological study, T2DM and/or HTN patients attending outpatient department at tertiary care hospitals and private clinics across 54 cities in India were enrolled. The primary outcome measure was to determine the prevalence of depression in T2DM, HTN and T2DM + HTN patients. Association of depression with patients’ demography, socio-economic status, anxiety, and clinically diagnosed insomnia were also investigated. Results. Of 1829 patients, the prevalence of depression in T2DM, HTN and T2DM+HTN cases were found to be 51.03%, 46.94% and 48.64%, respectively. A higher proportion of patients with uncontrolled T2DM and HTN reported depression (T2DM: 77.64% vs. 22.36%; HTN: 72.49% vs. 27.51%). There was a significant association between anxiety and severity of depression across all indications (p<0.0001). Depression was significantly associated with complications in T2DM (p=0.0001) and comorbidities in T2DM + HTN (p=0.0023) cases. Conclusion. Depression is highly prevalent and has a direct significant association with various socio-demographic variables and anxiety in Indian patients with T2DM and/or HTN.

Źródło:

European Journal of Clinical and Experimental Medicine; 2019, 4; 315-325
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 3.

Tytuł:

Diabetic autonomic neuropathy of the gastrointestinal tract - etiopathogenesis, diagnosis, treatment and complications

Autorzy:

Kuzemko, Dorota
Rymarz, Ewa
Prystupa, Andrzej
Dzida, Grzegorz
Mosiewicz, Jerzy

Powiązania:

https://bibliotekanauki.pl/articles/972715.pdf

Data publikacji:

2017

Wydawca:

Instytut Medycyny Wsi

Tematy:

diabetic neuropathies
diabetes complications
diabetes mellitus
gastrointestinal autonomic neuropathy

Opis:

Introduction. Late complications of diabetes mellitus are a serious challenge for physicians treating diabetic patients. Micro- and macro-angiopathic changes are of the most severe sequels. However, it should be remembered that the effects of long-term diabetes are also associated with changes in the peripheral nervous system. One of the complications most troublesome for patients is diabetic autonomic neuropathy of the gastrointestinal (GI) tract. Objective. The review article presents the pathogenesis of diabetic neuropathy of the autonomous gastrointestinal tract, and advances in the diagnosis and treatment of this disease. The study used materials in the database which demonstrate current standards of conduct, based on the principles of EBM. Brief description of the state of knowledge. Diabetic neuropathy is one of the most common complications of diabetes mellitus. According to epidemiologists, it affects 10% to even 100% of patients with long-standing disease. Damage to the nervous fibres mainly results from hyperglycaemia, which leads to the typical symptoms of dysfunction of GI tract segments. The main additional examinations include abdominal ultrasound (US) and abdominal X-ray. In cases with oesophageal disorders accompanied by dysphagia, gastroscopy is found useful for excluding possible neoplastic lesions. The gold standard for evaluation of gastric emptying is radioisotopic scintigraphy, however it is available only in some specialistic departments. Other recommended methods include: manometry, EGG, insulin tests, NMR and expiratory tests. To date, the problem has been managed symptomatically; in special cases, surgical interventions have been required. Conclusions. At present, a wide array of treatment options is available, including new forms of drugs and less radical surgical procedures carried out in numerous centres worldwide.

Źródło:

Journal of Pre-Clinical and Clinical Research; 2017, 11, 1; 6-9
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 4.

Tytuł:

Physical activity in type 2 diabetes mellitus: a review

Autorzy:

Burooj, Ahmed

Powiązania:

https://bibliotekanauki.pl/articles/33777868.pdf

Data publikacji:

2024-04-10

Wydawca:

Gdański Uniwersytet Medyczny

Tematy:

T2DM
Exercise
Diabetes
Diabetes Mellitus
Physical Activity

Opis:

Introduction This literature review explores the role of physical activity (PA) in managing and preventing type 2 diabetes mellitus (T2DM), synthesizing the latest guidelines for all T2DM patients. Following PRISMA guidelines, it identifies specific areas for further research. Material and Methods Indexing services (PubMed and Scopus) were used to identify relevant studies, emphasizing original research, review articles, and updated institutional guidelines spanning 2017-2023. The following keywords were used: diabetes, physical activity, type 2 diabetes mellitus, PA, and exercise. Proposal and opinion articles, non-English papers (or those lacking full-text translation), studies involving non-human subjects, pediatric populations or with skewed gender distribution were excluded. Results PA improves quality of life, BMI, glycemic control and well-being. Effects vary by activity domain, such as work or leisure time. Recommendations suggest 60 daily minutes of exercise for children, 150 weekly minutes of moderate intensity exercise for adults, and screening for adverse events. A “sit-less” approach is proposed for those unable to maintain regular activity, with glycemic monitoring for those with variability. Conclusions PA is crucial in T2DM management. Conflicting findings regarding glycemic control warrant further investigation to ascertain causes, whether related to bias or other factors.

Źródło:

European Journal of Translational and Clinical Medicine; 2024, 7, 1; 97-105
2657-3148
2657-3156

Pojawia się w:

European Journal of Translational and Clinical Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 5.

Tytuł:

Profilaktyka i leczenie cukrzycy typu 2 – walka z chorobą i edukacja zdrowotna
Prevention and Treatment of Type 2 Diabetes – Fight Against the Disease and Health Education

Autorzy:

Gostyńska, Maria M.

Powiązania:

https://bibliotekanauki.pl/articles/416461.pdf

Data publikacji:

2018-08

Wydawca:

Najwyższa Izba Kontroli

Tematy:

diabetes
diabetic foot
metabolic control
diabetes complications
risk factors

Opis:

Diabetes is considered a civilisation disease whose treatment, since the diagnosis, continues throughout lifetime. This is a huge burden to the health insurance system. From the data of the National Health Fund (Polish: Narodowy Fundusz Zdrowia, NFZ) it transpires that the number of those suffering from type 2 diabetes exceeds 1.6 million. In fact, this number is higher since some persons having diabetes have never been diagnosed. That is why it is very important, for both the health system, and the patients themselves and their relatives, to have access to education, appropriate prevention and, once diagnosed, to start treatment as soon as possible so that not to develop complications or to delay them. Therefore, the Supreme Audit Office conducted an audit to evaluate the activities aimed at diagnosing those threatened with and suffering from type 2 diabetes at an early stage, and at implementing effective methods for treating the disease.

Źródło:

Kontrola Państwowa; 2018, 63, 4 (381); 60-76
0452-5027

Pojawia się w:

Kontrola Państwowa

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 6.

Tytuł:

Novel diabetes classification approach based on CNN-LSTM: enhanced performance and accuracy

Autorzy:

Ayat, Yassine
Benzekri, Wiame
El Moussati, Ali
Mir, Ismail
Benzaouia, Mohammed
El Aouni, Abdelaziz

Powiązania:

https://bibliotekanauki.pl/articles/31341646.pdf

Data publikacji:

2024

Wydawca:

Polska Akademia Nauk. Polskie Towarzystwo Diagnostyki Technicznej PAN

Tematy:

diabetes
diabetes classification
dataset balancing
combined model
personalized healthcare

Opis:

This paper deals with the development of an approach for diabetes classification harnessing ConvolutionalNeural-network (CNN) and a Long-Short-Term-Memory (LSTM) model. The proposed method harnesses the strengths of LSTM and CNN architectures to effectively capture sequential patterns and extract meaningful features from the input data. A comprehensive dataset containing relevant features for diabetes patients is used to train and evaluate the classifiers. Evaluation metrics such as kappa score, F1-score, accuracy, precision, and recall are employed in ordre to assess the performance of each model. The results demonstrate that the CNNLSTM model outperforms other models, including Logistic Regression, Random Forest, SVM, and KNN, achieving an impressive accuracy of 97%. These findings shed light on the effectiveness of the proposed approach in accurately classifying diabetes, resulting in significant advancement in diabetes diagnosis and treatment and opening up exciting possibilities for personalized healthcare.

Źródło:

Diagnostyka; 2024, 25, 1; art. no. 2024112
1641-6414
2449-5220

Pojawia się w:

Diagnostyka

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 7.

Tytuł:

What next for diabetes mellitus?

Autorzy:

Witek, Bożena
Rochon-Szmejchel, Danuta
Kamińska, Dorota

Powiązania:

https://bibliotekanauki.pl/articles/472510.pdf

Data publikacji:

2016

Wydawca:

Uniwersytet Pedagogiczny im. Komisji Edukacji Narodowej w Krakowie

Tematy:

diabetes
insulin
glucagon

Źródło:

Annales Universitatis Paedagogicae Cracoviensis. Studia ad Didacticam Biologiae Pertinentia; 2016, VI; 6-19
2083-7267
2450-3487

Pojawia się w:

Annales Universitatis Paedagogicae Cracoviensis. Studia ad Didacticam Biologiae Pertinentia

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 8.

Tytuł:

An analysis of the level of knowledge about diabetes among pregnant women

Autorzy:

Buraczewska, Ewelina
Sokołowska, Barbara
Mazurkiewicz, Barbara
Borzęcki, Andrzej

Powiązania:

https://bibliotekanauki.pl/articles/552812.pdf

Data publikacji:

2016

Wydawca:

Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych

Tematy:

diabetes
pregnancy
knowledge.

Źródło:

Family Medicine & Primary Care Review; 2016, 3; 225-229
1734-3402

Pojawia się w:

Family Medicine & Primary Care Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 9.

Tytuł:

Pancreas transplantation in a patient after total pancreatectomy due to chronic pancreatitis – the first case in Poland

Autorzy:

Durlik, Marek
Baumgart, Katarzyna

Powiązania:

https://bibliotekanauki.pl/articles/1393931.pdf

Data publikacji:

2016

Wydawca:

Index Copernicus International

Tematy:

pancreas transplantation
brittle diabetes
pancreatogenic diabetes
total pancreatectomy
chronic pancreatitis

Opis:

Chronic pancreatitis is an inflammatory disease that may require surgical intervention. In some patients a total pancreatectomy is necessary. Such patients develop diabetes, which in some cases may be difficult to control. When standard insulin treatment is unsuccessful and the patient has frequent blood glucose swings with life-threatening hiper- and hypoglycemic episodes, a pancreas transplant should be considered.

Źródło:

Polish Journal of Surgery; 2016, 88, 2; 106-108
0032-373X
2299-2847

Pojawia się w:

Polish Journal of Surgery

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 10.

Tytuł:

Ocena sposobu żywienia i znajomości zagadnień związanych z cukrzycą wśród osób chorych na cukrzycę – badania wstępne
Assessment of the methods of nutrition and knowledge connected with diabetes among diabetic patients − preliminary research

Autorzy:

Pustułka, Karolina
Kucharska, Edyta
Sąsiadek, Wojciech

Powiązania:

https://bibliotekanauki.pl/articles/581760.pdf

Data publikacji:

2018

Wydawca:

Wydawnictwo Uniwersytetu Ekonomicznego we Wrocławiu

Tematy:

cukrzyca
badanie ankietowe
wiedza diabetyków
dieta
diabetes
survey
diabetes knowledge
diet

Opis:

Przestrzeganie odpowiedniej diety, oprócz wsparcia farmakologicznego, stanowi ważny element w leczeniu cukrzycy. Celem pracy było zbadanie podstawowej wiedzy diabetyków na temat cukrzycy i jej powikłań z zastosowaniem metody badania ankietowego. Ankieta została przeprowadzona w 2016 roku na próbie 236 osób chorych na cukrzycę typu 1 lub 2. Największą grupę badanych tworzyły osoby z cukrzycą wykrytą stosunkowo niedawno, czyli ok. 2-5 lat temu. Prawie 3/4 respondentów kontroluje stopień swojej choroby u diabetologa w przychodni bądź w poradni cukrzycowej. Większość ankietowanych jest w dużym stopniu świadoma zasad diety zalecanej dla cukrzyków, a prawie połowa z nich ją stosuje.
Observing a proper diet in addition to pharmacological support is an important element in the treatment of diabetes.The aim of the study was to examine the basic knowledge of diabetics on diabetes and its complications, using the survey method. The survey was conducted in 2016 on a sample of 236 people with diabetes type 1 or 2. The largest group of respondents consisted of people with diabetes detected relatively recently, about 2-5 years ago. Almost three quarters of respondents control the degree of their disease at a diabetologist in a practice or diabetic clinic. Respondents most often go for control visits once every six months or once every 3 months. Most of the respondents are largely aware of the principles of the diet recommended for diabetics, and almost half of them use it. Unfortunately, among the respondents was also the percentage of respondents who did not follow a proper diet and do not even know its principles.

Źródło:

Prace Naukowe Uniwersytetu Ekonomicznego we Wrocławiu; 2018, 542; 142-160
1899-3192

Pojawia się w:

Prace Naukowe Uniwersytetu Ekonomicznego we Wrocławiu

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 11.

Tytuł:

Disorders of carbohydrate metabolism and their relationship with the prevalence of cancer in patients with acromegaly – authors’ own observations

Autorzy:

Malicka, Joanna
Kurowska, Maria
Dudzińska, Marta
Smoleń, Agata
Oszywa-Chabros, Anna
Tarach, Jerzy

Powiązania:

https://bibliotekanauki.pl/articles/553129.pdf

Data publikacji:

2016

Wydawca:

Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych

Tematy:

acromegaly
diabetes
prediabetes
malignancy.

Źródło:

Family Medicine & Primary Care Review; 2016, 3; 291-293
1734-3402

Pojawia się w:

Family Medicine & Primary Care Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 12.

Tytuł:

PREVELANCE OF METFORMIN-INDUCED GASTROINTESTINAL PROBLEMS

Autorzy:

Sadeeqa, Saleha
Fatima, Madeeha
Latif, Sumera
Afzal, Hafsa
Nazir, Saeed Ur Rashid
Saeed, Hamid

Powiązania:

https://bibliotekanauki.pl/articles/895256.pdf

Data publikacji:

2019-12-29

Wydawca:

Polskie Towarzystwo Farmaceutyczne

Tematy:

Diabetes Mellitus
metformin
Gastrointestnal

Opis:

Metformin is used as an anti-diabetic drug among oral hypoglycemic drugs, which produces many gastrointestinal problems. Study aims to investigate the effect of metformin induced gastrointestinal problems and its prevalence. A cross-sectional study design was adapted using convenience sampling technique, at different Diabetic Centers of Lahore and Faisalabad, Pakistan from, June-2017 to November-2017. A total of 300 male and female patients participated in the study between 26 to 85 years and diagnosed with type-II diabetes. Data was directly collected from the patients and prevalence of metformin-induced gastrointestinal intolerance was determined by the symptoms of the patients. Data was analyzed by SPSS version 21. Results showed a significant difference between gender and symptoms (p=0.029). Moreover, the gastrointestinal problems were found to be dose related. A significant difference existed between patients who were taking 500mg and those taking 850 mg of metformin (p=0.006), patients who were taking 500mg and those taking 1000mg of metformin (p=0.000) and patients who were taking 850mg with those taking 1000mg of metformin (p=0.022). The prevelance of metformin-induced gastrointestinal symptoms was 45.8%. Most commonly occurring symptoms were, constipation (41.35%) followed by dyspepsia (27.89%), abdominal pain (26.92%), bloating and heart burn (25%), indigestion (15.38%), anorexia (11.54%), diarrhea (6.58%), flatulence (7.69%), nausea (6.73%) and vomiting (2.88%). It was concluded that gastrointestinal intolerance was more in females as compared to males. The gastrointestinal problems increased with the increase in dose. The side effects occurred were irrespective of the age and the most common gastrointestinal symptom was found to be constipation.

Źródło:

Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 6; 1073-1077
0001-6837
2353-5288

Pojawia się w:

Acta Poloniae Pharmaceutica - Drug Research

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 13.

Tytuł:

Spectroscopic Investigation of the Hair of Diabetic Patients

Autorzy:

Ali, A.
Verma, N.V.

Powiązania:

https://bibliotekanauki.pl/articles/412256.pdf

Data publikacji:

2013

Wydawca:

Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN

Tematy:

diabetes
metals
hair
AAS

Opis:

Diabetes is a major disease condition that is accountable for 5% of annual cause of death globally and it continues to escalate. In this research the levels of minerals in persons with type 2 diabetes were investigated using hair as the biopsy specimen. The philosophy behind is that minerals are involved in countless metabolic functions in all phases of the life process, an imbalance of which can have widespread implication, while hair due to its physiology serves an invaluable record of the body's exposure to minerals. Hair metal testing is a fascinating new diagnostic tool and often gives unexpected clues to mineral imbalances in the body. In executing the research samples of head hair collected from 6 type 2 diabetic patients were washed to remove exogenous contaminants, then subjected to open vessel acid digestion and subsequent analysis for the elements Ca, Cd, Cr, Cu Fe, K, Mg, Na and Zn using Flame Atomic Absorption Spectroscopy (FLAAS). After comparing the concentration of the elements to a range that is considered to be normal it was found that Ca, Zn, Fe, Mg, K, Cu, Cd and Cr were off range while Na was normal. Upon investigating the function and effects of the elements that were off range it was found that a deficiency of chromium and an excess of iron could be a possible cause of diabetes.

Źródło:

International Letters of Chemistry, Physics and Astronomy; 2013, 3; 37-45
2299-3843

Pojawia się w:

International Letters of Chemistry, Physics and Astronomy

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 14.

Tytuł:

Urolithins and their possible implications for diabetic kidney

Autorzy:

Kotewicz, Milena
Lewko, Barbara

Powiązania:

https://bibliotekanauki.pl/articles/2203255.pdf

Data publikacji:

2022-05-31

Wydawca:

Gdański Uniwersytet Medyczny

Tematy:

diabetes
kidney
podocytes
urolithins

Opis:

The increasing prevalence of diabetic kidney disease (DKD), a common complication of type 1 and type 2 diabetes, is becoming a leading risk factor of developing end stage renal disease (ESRD). The multiple mechanisms involved in renal tissue damage are a challenge for effective targeted therapy. Urolithins are metabolites generated by gut microbiota upon dietary intake of plant-derived elagitannins. Multidirectional effects of these compounds include their anti-inflammatory, antioxidant, anti-proliferatory, anti-migratory and antiglycative properties that are mediated by modulation of signaling pathways and gene expression. Biochemical properties of urolithins indicate their capacity to regulate numerous mechanisms responsible for developing the hyperglycemia-induced tissue injury. The potentially beneficial effects of urolithins on podocytes, the most vulnerable renal cells should be particularly considered. The purpose of this review is to provide the evidence from the in vivo and in vitro studies showing that urolithin-based therapy could be a useful tool for protecting the kidneys from damage in diabetes.

Źródło:

European Journal of Translational and Clinical Medicine; 2022, 5, 1; 53-63
2657-3148
2657-3156

Pojawia się w:

European Journal of Translational and Clinical Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 15.

Tytuł:

Complex relationships between endocrinopathies and obstructive sleep apnea syndrome

Autorzy:

Szymańska, Monika
Mizerski, Grzegorz
Kiciński, Paweł

Powiązania:

https://bibliotekanauki.pl/articles/454873.pdf

Data publikacji:

2017

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

obstructive sleep apnea endocrinopathies
diabetes

Opis:

Sleep-related disordered breathing (SRDB) is a term covering a heterogeneous group of conditions with a similar clinical picture yet different pathogenesis. Nocturnal episodes of obstructive apnoea, leading to repeated periods of desaturation and re-oxygenation, activate chemoreceptors and increase the activity of the sympathetic as well as renin-angiotensin-aldosterone system. Moreover, the generation of free radicals and proinflammatory cytokines increases. All the above mentioned disturbances interfere with the function of endocrine glands. On the other hand, many endocrine disorders are associated with an increased risk of obstructive sleep apnoea syndrome (OSAS). In this paper, we discuss relationships between selected endocrinopathies and OSAS.

Źródło:

European Journal of Clinical and Experimental Medicine; 2017, 3; 268-272
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 16.

Tytuł:

Metastatic tumors of the pituitary gland as a cause of diabetes insipidus in 4 patients

Autorzy:

Kurowska, Maria
Malicka, Joanna
Tarach, Jerzy
Dudzińska, Marta

Powiązania:

https://bibliotekanauki.pl/articles/551631.pdf

Data publikacji:

2013

Wydawca:

Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych

Tematy:

pituitary metastases
central diabetes insipidus

Źródło:

Family Medicine & Primary Care Review; 2013, 3; 499-501
1734-3402

Pojawia się w:

Family Medicine & Primary Care Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 17.

Tytuł:

Homocysteine as a non-classical risk factor for atherosclerosis in relation to pharmacotherapy of type 2 diabetes mellitus

Autorzy:

Borowska, Magdalena
Dworacka, Marzena
Winiarska, Hanna
Krzyżagórska, Ewa

Powiązania:

https://bibliotekanauki.pl/articles/1038542.pdf

Data publikacji:

2017

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

homocysteine
atherosclerosis
type 2 diabetes

Opis:

Aims. The aim of our study was to evaluate which of the pharmacotherapeutic methods that are frequently used to treat type 2 diabetes is associated with the most beneficial profile in relation to pro-atherogenic homocysteine levels. Patients and Methods. We measured the serum homocysteine level in 182 patients with type 2 diabetes treated with metformin (89), treated with insulin in combination with metformin (31), receiving sulfonylureas (31) and treated conventionally with insulin (31). The total homocysteine levels in the serum were assayed. To exclude the influence of selected metabolic and anthropometric factors on the differences between the examined groups, multivariate analysis of covariance was used (ANCOVA). In this analysis, serum homocysteine concentration was the dependent variable, while diabetes duration, waist circumference, HbA1c, 1,5-anhydro-D-glucitol, fasting glycaemia and peptide C were used as covariates. Results. The serum homocysteine levels in patients treated with insulin in monotherapy were significantly higher than what was observed in the metformin treated subjects and in the patients receiving insulin combined with metformin. The analysis of covariance also confirmed that the differences between the therapeutic groups were affected by waist circumference and the C-peptide levels. Conclusion. We conclude that conventional insulin therapy may have a negative effect on pro-atherogenic homocysteine levels in patients with type 2 diabetes. This study revealed that pro-atherogenic homocysteine levels may not only be modified by pharmacotherapy of type 2 diabetes, but also by beta cell secretory function and abdominal obesity.

Źródło:

Acta Biochimica Polonica; 2017, 64, 4; 603-607
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 18.

Tytuł:

Potoczna wiedza o cukrzycy: porównanie osób posiadających i nieposiadających chorego na cukrzycę w rodzinie
Lay knowledge of diabetes - the comparison between family members of diabetic patients and those who had no family experience with diabetes

Autorzy:

Olchowska-Kotala, Agnieszka

Powiązania:

https://bibliotekanauki.pl/articles/2139048.pdf

Data publikacji:

2012

Wydawca:

Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego

Tematy:

diabetes
illness representations
healthy individuals

Opis:

The aim of the study was to examine the perception of diabetes and the knowledge about this disease. Participants were divided into two groups: the first one consisted of family members of diabetic patients (56 individuals; M age = 54) whereas the second one comprised those who had no family experiences with diabetes (104 individuals; M age = 55). In order to examine the perception of diabetes modified version of IPQ-R (The Revised Illness Perception Questionnaire), enabling examination of healthy individuals was applied. Additionally, participants were to decide whether certain given information on diabetes was true or false. Participants in both groups considered diabetes as a serious chronic disease which can be successfully treated and the course of which is largely dependent on a patient’s behaviour. In both groups there were false assumptions regarding the causes of the disease and opinions discordant with medical knowledge. It would be advisable to organize educational campaigns and screening programmes for the family members. As a result, family members would be able to provide better support for the patient and could also recognize dysfunctions of their own organism early enough.

Źródło:

Acta Universitatis Lodziensis. Folia Psychologica; 2012, 16; 47-59
2353-4842

Pojawia się w:

Acta Universitatis Lodziensis. Folia Psychologica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 19.

Tytuł:

Parity does not affect diabetes complications in women with type 1 diabetes

Autorzy:

Cypryk, K.
Grycewicz, J.
Świerzewska, P.
Kosiński, M.
Lewiński, A.
Żurawska-Klis, M.

Powiązania:

https://bibliotekanauki.pl/articles/2081577.pdf

Data publikacji:

2018

Wydawca:

Instytut Medycyny Wsi

Tematy:

diabetes
obstetric history
chronic complications

Opis:

Introduction. The problem concerning the impact of pregnancy on diabetic complications is a matter for discussion as there is some evidence suggesting that pregnancy may trigger development or progression of diabetic chronic complications. However, currently available data concerning this issue is still controversial. Objective. The aim of the study was to evaluate the impact of obstetric history on the development of chronic microangiopatic and macroangiopatic complications in type 1 diabetic women. Materials and Method. The retrospective study comprised 226 white Caucasian type 1 diabetic women, including 190 parous and 36 nulliparous women. Anthropometric data, information concerning the course of the disease, including metabolic control and chronic complications, together with obstetric history, were registered. Results. Parous women were older (p<0.001), but did not differ significantly regarding metabolic control in the course of the disease (p>0.05) and diabetes duration (p>0.05) from nulliparous subjects. There were no significant differences in the incidence (p>0.05) nor onset (p>0.05) of chronic diabetes complications between the groups. The number of deliveries did not correlate with either the incidence nor the onset of chronic complications. Longer DM duration at the moment of first delivery was related to the higher incidence of retinopathy (p<0.01), nephropathy (p<0.05) and neuropathy (p<0.001). Conclusions. The incidence of chronic diabetic complications does not differ between parous women and the subjects that were never pregnant, and is not related to the number of pregnancies.

Źródło:

Annals of Agricultural and Environmental Medicine; 2018, 25, 1; 114-119
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 20.

Tytuł:

High resolution ultrasonography of the tibial nerve in diabetic peripheral neuropathy
Zastosowanie ultrasonografii wysokiej rozdzielczości w badaniu nerwu piszczelowego u pacjentów z cukrzycową neuropatią obwodową

Autorzy:

Singh, Kunwarpal
Gupta, Kamlesh
Kaur, Sukhdeep

Powiązania:

https://bibliotekanauki.pl/articles/1033301.pdf

Data publikacji:

2017

Wydawca:

Medical Communications

Tematy:

diabetes mellitus
tibial nerve
ultrasonography

Opis:

Aim of the study: High-resolution ultrasonography of the tibial nerve is a fast and non invasive tool for diagnosis of diabetic peripheral neuropathy. Our study was aimed at finding out the correlation of the cross sectional area and maximum thickness of nerve fascicles of the tibial nerve with the presence and severity of diabetic peripheral neuropathy. Material and methods: 75 patients with type 2 diabetes mellitus clinically diagnosed with diabetic peripheral neuropathy were analysed, and the severity of neuropathy was determined using the Toronto Clinical Neuropathy Score. 58 diabetic patients with no clinical suspicion of diabetic peripheral neuropathy and 75 healthy non-diabetic subjects were taken as controls. The cross sectional area and maximum thickness of nerve fascicles of the tibial nerves were calculated 3 cm cranial to the medial malleolus in both lower limbs. Results: The mean cross sectional area (22.63 +/– 2.66 mm2 ) and maximum thickness of nerve fascicles (0.70 mm) of the tibial nerves in patients with diabetic peripheral neuropathy compared with both control groups was significantly larger, and statistically significant correlation was found with the Toronto Clinical Neuropathy Score (p < 0.001). The diabetic patients with no signs of peripheral neuropathy had a larger mean cross sectional area (14.40 +/– 1.72 mm2 ) and maximum thickness of nerve fascicles of the tibial nerve (0.40 mm) than healthy non-diabetic subjects (12.42 +/– 1.01 mm2 and 0.30 mm respectively). Conclusion: The cross sectional area and maximum thickness of nerve fascicles of the tibial nerve is larger in diabetic patients with or without peripheral neuropathy than in healthy control subjects, and ultrasonography can be used as a good screening tool in these patients.
Cel pracy: Ultrasonografia wysokiej rozdzielczości nerwu piszczelowego jest szybką i nieinwazyjną metodą możliwą do wykorzystania w rozpoznaniu cukrzycowej neuropatii obwodowej. Celem naszej pracy było ustalenie, czy istnieje zależność pomiędzy polem przekroju poprzecznego oraz maksymalną grubością pęczków nerwu piszczelowego a występowaniem i zaawansowaniem cukrzycowej neuropatii obwodowej. Materiał i metoda: Badaniu poddano 75 pacjentów cierpiących na cukrzycę typu 2 z klinicznym rozpoznaniem cukrzycowej neuropatii obwodowej. Stopień zaawansowania neuropatii oceniany był za pomocą Klinicznej skali neuropatii Toronto (Toronto Clinical Neuropathy Score). Grupę kontrolną w badaniu stanowiło 58 pacjentów z cukrzycą bez objawów klinicznych cukrzycowej neuropatii obwodowej oraz 75 zdrowych osób. Pole przekroju poprzecznego oraz maksymalna grubość pęczków nerwu piszczelowego wyliczane były na wysokości 3 cm powyżej kostki przyśrodkowej w obu kończynach dolnych. Wyniki: Średnie pole przekroju poprzecznego (2,63 +/− 2,66 mm2) oraz maksymalna grubość pęczków nerwu piszczelowego (0,70 mm) u pacjentów z cukrzycową neuropatią obwodową były istotnie statystycznie większe niż u osób z obu grup kontrolnych. Stwierdzono także występowanie istotnej statystycznie zależności pomiędzy wielkością tych parametrów a stopniem zaawansowania cukrzycowej neuropatii obwodowej według Klinicznej skali neuropatii Toronto (p < 0,001). U pacjentów chorujących na cukrzycę bez występowania objawów klinicznych cukrzycowej neuropatii obwodowej pole przekroju poprzecznego (14,40 +/− 1,72 mm2) oraz maksymalna grubość pęczków nerwu piszczelowego (0,40 mm) były większe niż u zdrowych uczestników badania (odpowiednio 12,42 +/− 1,01 mm2 i 0,30 mm). Wnioski: Przekrój oraz maksymalna grubość pęczków nerwu piszczelowego są większe niż u osób zdrowych zarówno u pacjentów z cukrzycą cierpiących na cukrzycową neuropatię obwodową, jak i bez klinicznych objawów neuropatii. Ultrasonografia może być z powodzeniem wykorzystywana u chorych z cukrzycą jako badanie przesiewowe pod kątem występowania cukrzycowej neuropatii obwodowej. Artykuł w wersji polskojęzycznej jest dostępny na stronie http://jultrason.pl/index.php/wydawnictwa/volume-17-no-71

Źródło:

Journal of Ultrasonography; 2017, 17, 71; 246-252
2451-070X

Pojawia się w:

Journal of Ultrasonography

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 21.

Tytuł:

Wybrane aspekty przygotowania do samoopieki w zakresie dietoterapii pacjentów z cukrzycą typu 2
Selected aspects of preparing for self-care in the field of diet therapy in patients with type 2 diabetes

Autorzy:

Sałata, Magdalena
Rezmerska, Leokadia

Powiązania:

https://bibliotekanauki.pl/articles/1030077.pdf

Data publikacji:

2016

Wydawca:

Państwowa Uczelnia Zawodowa we Włocławku

Tematy:

self-care
diet therapy
diabetes

Opis:

Introduction. Currently, diabetes is considered to be one of the most common chronic diseases in Poland and in the world. The diet applied by patients with diabetes helps to control the proper level of sugar in the blood and is a very important part of the treatment. It also helps reduce overweight, obesity and minimizes the risk of diabetes complications. Aim. The aim of the research in this study was to analyze selected aspects of behavior in terms of diet therapy in patients with type 2 diabetes in an effort to prepare for self-care. Material and methods. The study was carried out among 100 patients with type 2 diabetes using the method of diagnostic survey, based on the original questionnaire. Results. Patients mostly describe their knowledge on the diet in diabetes as an average. Such an assessment was performed more commonly by male than by female respondents. Lack of sufficient knowledge in this matter was typical for most respondents in the oldest age groups. Respondents in most cases followed dietary guidelines received from the members of the therapeutic team. Conclusions. Regardless of gender and age the patients in the course of type 2 diabetes most commonly specified their knowledge about diabetic diet as an average. They declared their following dietary recommendations they received from members of the therapeutic team. Gender and age did not significantly determine the scope of knowledge and behavior of patients regardingthe diet in type 2 diabetes.
Wstęp. Obecnie cukrzyca uznawana jest za jedną z najbardziej rozpowszechnioną chorób przewlekłych w Polsce i na świecie. Dieta stosowana przez chorych w cukrzycy wspomaga kontrolę prawidłowego poziomu cukru we krwi i stanowi bardzo ważny element leczenia. Sprzyja także redukcji nadwagi, otyłości i minimalizuje ryzyko powikłań cukrzycy. Cel. Celem przeprowadzonych badań w niniejszej pracy była analiza wybranych aspektów zachowań w zakresie dietoterapii pacjentów w przebiegu cukrzycy typu 2 w dążeniu do przygotowania do samoopieki. Materiał i metody. Badania przeprowadzono wśród 100 pacjentów z rozpoznaną cukrzycą typu 2 z wykorzystaniem metody sondażu diagnostycznego, w oparciu o autorski kwestionariusz ankiety. Wyniki. Pacjenci najczęściej określali swój zasób wiedzy na temat diety w cukrzycy jako przeciętny. Takiej oceny dokonywali częściej mężczyźni niż kobiety. Brak dostatecznej wiedzy w tym zakresie prezentowali najczęściej respondenci z najstarszych grup wiekowych. Respondenci w większości przestrzegali wytycznych dotyczących diety, które otrzymali od członków zespołu terapeutycznego. Wnioski. Niezależnie od płci i wieku pacjenci w przebiegu cukrzycy typu 2 określali najczęściej swój zasób wiedzy na temat diety cukrzycowej jako przeciętny. Deklarowali także przestrzeganie zaleceń dietetycznych, które otrzymali od członków zespołu terapeutycznego. Płeć i wiek nie determinowały istotnie zasobu wiedzy i prezentowanych zachowań pacjentów dotyczących żywienia w cukrzycy typu 2.

Źródło:

Innowacje w Pielęgniarstwie i Naukach o Zdrowiu; 2016, 1, 1; 45-59
2451-1846

Pojawia się w:

Innowacje w Pielęgniarstwie i Naukach o Zdrowiu

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 22.

Tytuł:

The design of an insulin pump concept of closing the loop

Autorzy:

Hawłas, H.
Lewenstein, K.

Powiązania:

https://bibliotekanauki.pl/articles/385242.pdf

Data publikacji:

2009

Wydawca:

Sieć Badawcza Łukasiewicz - Przemysłowy Instytut Automatyki i Pomiarów

Tematy:

insulin pump
diabetes
artificial pancreas

Opis:

This paper explains what insulin pump is and outlines basic requirements for such device. The material presented in this paper is an attempt to collect actual knowledge about closed loop insulin delivery systems. From scientific point of view we are going to propose the closed loop insulin-dispensing device with control built on the base of predictive neural network system. The blocks of such systems are listed, and main problems to overcome are defined.

Źródło:

Journal of Automation Mobile Robotics and Intelligent Systems; 2009, 3, 4; 195-198
1897-8649
2080-2145

Pojawia się w:

Journal of Automation Mobile Robotics and Intelligent Systems

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 23.

Tytuł:

Association between a nucleotide polymorphism in the calpain 10 gene and carbohydrate metabolism disturbances in patients with polycystic ovary syndrome

Autorzy:

Szydlarska, Dorota
Machaj, Małgorzata

Powiązania:

https://bibliotekanauki.pl/articles/552368.pdf

Data publikacji:

2016

Wydawca:

Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych

Tematy:

diabetes
hyperandrogenism
single nucleotide polymorphism.

Źródło:

Family Medicine & Primary Care Review; 2016, 4; 497-500
1734-3402

Pojawia się w:

Family Medicine & Primary Care Review

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 24.

Tytuł:

Roux-en-Y gastric bypass as a cure of iatrogenic steroid-induced diabetes

Autorzy:

Poznanska, Grazyna
Hogendorf, Piotr
Czupryniak, Leszek
Smolewski, Piotr
Grząsiak, Oliwia
Szmiel, Aneta
Kasiarz, Anna
Strzelczyk, Janusz
Durczyński, Adam

Powiązania:

https://bibliotekanauki.pl/articles/1392077.pdf

Data publikacji:

2019

Wydawca:

Index Copernicus International

Tematy:

bariatric surgery
cure
iatrogenic diabetes
Roux-en-Y gastric bypass
steroid induced diabetes
treatment

Opis:

Background: Steroid-induced diabetes (SIDM) is a frequently found clinical condition since steroid-based therapies continue to be widely used in hospital and ambulatory care. Recommended optimal treatment of SIDM includes similar glucose lowering strategies as in type 2 diabetes. This typical management cannot cure the disease, it can only control blood glucose. Recently, bariatric surgery has emerged as an effective treatment for type 2 diabetes mellitus. However, up to now, the usefulness of bariatric surgery in treatment of SIDM has not been evaluated. Case report: A 49-year-old female oncologic patient with steroid induced diabetes was referred for surgical treatment to the Department of General and Transplant Surgery in November 2009. Six years earlier, she underwent successful oncologic treatment with cladribine and high doses of steroids due to hairy cell leukemia. Finally complete hematologic remission with normalization of morphology and reduction of spleen size has been obtained. Prior to steroid treatment, blood glucose and urine examinations were within normal range. The patient was non-obese and had no family history of diabetes. Nevertheless, the patient developed diabetes secondary to corticosteroid therapy, poorly controlled by oral hypoglycemic agent (acarbosum), successfully converted to insulin therapy. Upon admission to the Department of General and Transplant Surgery, the patient was treated with 58 units of insulin per day. The patient was scheduled for Roux-en-Y gastric bypass (RYGB). Insulin was withdrawn immediately after the surgery and within six months after the surgery, plasma glucose and glycated hemoglobin (HbA1c-5.5%) levels reached and remained within normal range. Currently, eight years after surgery, body weight and BMI are 80 kg and 27.68 kg/m2, respectively. Plasma glucose and glycated hemoglobin are also normal. Importantly, from an oncological point of view, the patient has remained in continuous complete remission since October 2003. Conclusions: Our report is the first to our knowledge describing the effect of gastric bypass surgery on SIDM in a patient with prior hematologic malignancy. It proves that surgically altered anatomy of the small intestine improves glucose homeostasis previously disturbed with pro-diabetic medication.

Źródło:

Polish Journal of Surgery; 2019, 91, 5; 52-54
0032-373X
2299-2847

Pojawia się w:

Polish Journal of Surgery

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 25.

Tytuł:

A survey on prediction of diabetes using classification algorithms

Autorzy:

Khanwalkar, A.
Soni, R.

Powiązania:

https://bibliotekanauki.pl/articles/1818807.pdf

Data publikacji:

2021

Wydawca:

Stowarzyszenie Komputerowej Nauki o Materiałach i Inżynierii Powierzchni w Gliwicach

Tematy:

diabetes
diabetes prediction
algorithm
data mining
machine learning
cukrzyca
algorytm
eksploracja danych
uczenie maszynowe

Opis:

Purpose: Diabetes is a chronic disease that pays for a large proportion of the nation's healthcare expenses when people with diabetes want medical care continuously. Several complications will occur if the polymer disorder is not treated and unrecognizable. The prescribed condition leads to a diagnostic center and a doctor's intention. One of the real-world subjects essential is to find the first phase of the polytechnic. In this work, basically a survey that has been analyzed in several parameters within the poly-infected disorder diagnosis. It resembles the classification algorithms of data collection that plays an important role in the data collection method. Automation of polygenic disorder analysis, as well as another machine learning algorithm. Design/methodology/approach: This paper provides extensive surveys of different analogies which have been used for the analysis of medical data, For the purpose of early detection of polygenic disorder. This paper takes into consideration methods such as J48, CART, SVMs and KNN square, this paper also conducts a formal surveying of all the studies, and provides a conclusion at the end. Findings: This surveying has been analyzed on several parameters within the poly-infected disorder diagnosis. It resembles that the classification algorithms of data collection plays an important role in the data collection method in Automation of polygenic disorder analysis, as well as another machine learning algorithm. Practical implications: This paper will help future researchers in the field of Healthcare, specifically in the domain of diabetes, to understand differences between classification algorithms. Originality/value: This paper will help in comparing machine learning algorithms by going through results and selecting the appropriate approach based on requirements.

Źródło:

Journal of Achievements in Materials and Manufacturing Engineering; 2021, 104, 2; 77--84
1734-8412

Pojawia się w:

Journal of Achievements in Materials and Manufacturing Engineering

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 26.

Tytuł:

Long-term complications of diabetes and the risk of diabetic foot
Przewlekłe powikłania cukrzycy i ryzyko stopy cukrzycowej

Autorzy:

Krysiak-Zielonka, I.

Powiązania:

https://bibliotekanauki.pl/articles/2052827.pdf

Data publikacji:

2018

Wydawca:

Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej

Tematy:

diabetes mellitus
chronic complications of diabetes
diabetic foot
cukrzyca
przewlekłe powikłania cukrzycy
stopa cukrzycowa

Opis:

Background. Chronic complications of diabetes are presently the most vital problem in diabetology and the most significant challenge in the treatment of the diseases. Because of peripheral neuropathy and macroangiopathy, people with diabetes are particularly vulnerable to foot problems. The following study aims to evaluate the development of chronic complications in patients with type 2 diabetes, with a particular focus on the prevalence of limb ischemia symptoms. Material and methods. The study involved patients with type 2 diabetes mellitus and nondiabetic persons at a similar age. Diabetics were divided into 2 groups. Group 1 consisted of type 2 diabetic patients with no trophic lesions of the limbs; Group 2 included patients with diabetic foot disease; and the control group (Group 3) were the non-diabetic elderly. The study was to analyse the incidence of retinopathy, nephropathy and neuropathy in both diabetic groups. Besides, it was to evaluate changes in macroangiopathy among diabetic patients and the control group. Results. In all groups, symptoms of lower limb ischaemia were assessed, which allowed making comparisons between them. The studied material indicated that the occurrence of diabetic ulcers is mostly associated with macroangiopathy and its symptoms, polyneuropathy and particular types of neuropathy, retinopathy and horny foot skin. Conclusions. An interdisciplinary approach to the problem of the diabetic foot allows recognising its early clinical symptoms.
Wprowadzenie. Przewlekłe powikłania cukrzycy są obecnie najważniejszym problemem w diabetologii i stanowią największe wyzwanie w leczeniu cukrzycy. Z powodu obwodowej neuropatii i makroangiopatii chorzy na cukrzycę są grupą szczególnie narażoną na problemy zdrowotne stóp. Celem pracy jest ocena rozwoju przewlekłych powikłań u chorych na cukrzycę typu 2 ze szczególnym uwzględnieniem analizy częstości występowania objawów niedokrwienia kończyn. Materiał i metody. Badaniami objęto chorych z cukrzycą typu 2 oraz osoby niechorujące na cukrzycę w podobnym przedziale wiekowym. Diabetyków podzielono na 2 grupy. Grupę 1- stanowili chorzy na cukrzycę typu 2 bez zmian troficznych kończyn, grupę 2- stanowili chorzy z zespołem stopy cukrzycowej, grupę kontrolną (grupa 3)- stanowiły osoby w wieku podeszłym niechorujące na cukrzycę. Przeanalizowano występowanie retinopatii, nefropatii i neuropatii w obu grupach diabetyków. Oceny zmian o charakterze makroangiopatii dokonano wśród chorych na cukrzycę i w grupie kontrolnej. Wyniki. We wszystkich grupach oceniano objawy niedokrwienia kończyn dolnych. Dokonano porównań między grupami. W badanym materiale występowanie owrzodzeń cukrzycowych wiąże się w największym stopniu z makroangiopatią i jej objawami, polineuropatią i poszczególnymi typami neuropatii, retinopatią oraz występowaniem zrogowaciałego naskórka stóp. Wnioski. Interdyscyplinarne podejście do problemu stopy cukrzycowej umożliwia rozpoznawanie jej wczesnych objawów klinicznych.

Źródło:

Health Problems of Civilization; 2018, 12, 1; 14-21
2353-6942
2354-0265

Pojawia się w:

Health Problems of Civilization

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 27.

Tytuł:

Comparison of nutrition knowledge in patients with type 1 and type 2 diabetes

Autorzy:

Luszczki, E.
Deren, K.
Sobek, G.

Powiązania:

https://bibliotekanauki.pl/articles/3125.pdf

Data publikacji:

2015

Wydawca:

Instytut Medycyny Wsi

Tematy:

comparison
nutrition
knowledge
patient
diabetes type 1
diabetes type 2
human disease
metabolic disease

Opis:

Introduction. Diabetes as a non-infectious chronic metabolic disease is a problem of the contemporary world, including Poland. Behaviour therapy plays an important role in its treatment, i.e. proper diet and regular physical activity. Patient’s knowledge of nutrition principles is also an essential complement to the treatment, reducing the risk of late complications of diabetes. Objective. Assessment of the nutrition knowledge of patients with type 1 and type 2 diabetes. Materials and method. The study involved 300 randomly selected patients from Rzeszów and the surrounding area (135 patients with type 1 diabetes and 165 patients with type 2 diabetes) aged 8–78.The analysis was made using a survey questionnaire prepared by the authors of the study, conducted in the period July – December 2011. Results. The survey revealed that patients with type 1 diabetes have greater nutrition knowledge and knowledge about diabetes than patients with type 2 diabetes. On the other hand, they are less likely to comply with the recommendations of the diet prescribed by a doctor or a dietician. Conclusions. Patients with diabetes, regardless of age, type of diabetes, gender, or disease duration require continuous broadening of diabetes knowledge. Systematic training will teach patients proper eating habits related to their diet and lifestyle.

Źródło:

Journal of Pre-Clinical and Clinical Research; 2015, 09, 1
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 28.

Tytuł:

Stężenie glukozy w surowicy krwi w podostrym zatruciu chlorpyrifosem – insektycydem fosforoorganicznym
Serum glucose concentration in subacute intoxication with chlorpyrifos – Organophosphate insecticide

Autorzy:

Łukaszewicz-Hussain, Anna

Powiązania:

https://bibliotekanauki.pl/articles/2166328.pdf

Data publikacji:

2014-11-04

Wydawca:

Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi

Tematy:

chlorpyrifos
glukoza
cukrzyca
glucose
diabetes mellitus

Opis:

Wstęp: Z badań epidemiologicznych wynika, że narażenie na pestycydy fosforoorganiczne zwiększa ryzyko zachorowania na niektóre choroby, m.in. neurologiczne (np. chorobę Parkinsona, chorobę Alzheimera) i układu krążenia, a także na cukrzycę. Celem niniejszej pracy była ocena stężenia glukozy w surowicy krwi szczurów przy podostrym zatruciu niskimi dawkami chlorpyrifosu - związku fosforoorganicznego stosowanego jako insektycyd. Materiały i metody: Badania wykonano na szczurach samcach szczepu Wistar, którym przez 14 lub 28 dni sondą dożołądkowo podawano raz dziennie roztwór olejowy chlorpyrifosu w dawce 0,2; 2 lub 5 mg/kg m.c./dzień. Zwierzęta z grupy kontrolnej otrzymywały olej. W surowicy oznaczano stężenie glukozy metodą kolorymetryczną przy użyciu gotowych zestawów. Wyniki: Stwierdzono wzrost stężenia glukozy w surowicy po 14 dniach podawania chlorpyrifosu w najwyższej badanej dawce oraz po 28 dniach podawania związku we wszystkich badanych dawkach. Wnioski: Zarówno uzyskane wyniki (wzrost stężenia glukozy w surowicy krwi w podostrym zatruciu chlorpyrifosem), jak i dane z piśmiennictwa sugerują, że narażenie na insektycydy fosforoorganiczne może sprzyjać rozwojowi cukrzycy. U osób mających zawodowy kontakt z tymi związkami konieczne jest więc częstsze wykonywanie badań diagnostycznych w kierunku jej wczesnego wykrycia. Med. Pr. 2013;64(4):527–531
Background: Epidemiological studies suggest that exposure to organophosphate insecticides enhances the risk of various diseases, including neurological disorders, e.g. Parkinson's or Alzheimer's disease, arteriosclerosis and diabetes mellitus. For this reason the aim of the presented study was to estimate serum concentration of glucose in subchronic intoxication with low doses of chlorpyrifos, an organophosphate insecticide. Materials and Methods: The rats received chlorpyrifos at a daily dose of 0.2, 2 or 5 mg/kg b.w./day for 14 or 28 days. For biochemical determinations of serum glucose in the rats ready-to-use kit was applied. Results: In subacute intoxication with chlorpyrifos the increased serum concentration of glucose was observed after 14 days of intoxication with the highest dose (5 mg/kg b.w.) and after 28 days of intoxication with all dose levels used. Conclusions: The results of this study showing the increased concentration of serum glucose in subacute intoxication with low doses of chlorpyrifos, as well as the literature data suggest that exposure to organophosphate insecticides can increase the risk of diabetes mellitus. It may thus be concluded that people occupationally exposed to these compounds should be subjected to diagnostic tests for early detection of diabetes. Med Pr 2013;64(4):527–531

Źródło:

Medycyna Pracy; 2013, 64, 4; 527-531
0465-5893
2353-1339

Pojawia się w:

Medycyna Pracy

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 29.

Tytuł:

Diabetes association of polyps and colon cancer

Autorzy:

Miłek, Tomasz
Forysiński, Karol
Myrcha, Piotr
Ciostek, Piotr

Powiązania:

https://bibliotekanauki.pl/articles/1392134.pdf

Data publikacji:

2019

Wydawca:

Index Copernicus International

Tematy:

colorectal cancer
colorectal polyps
diabetes mellitus

Opis:

Aim: The aim of the study was to retrospectively assess the relationship between the occurrence of polyps and colon cancer in patients with type 2 diabetes. Methods: In 2014–2015, 976 colonoscopies were performed in patients. We compared the number of polyps with high-grade dysplasia and colorectal cancers in patients with and without diabetes. In addition, in the diabetic group we documented the relationship between HbA1C and the occurrence of polyps with high-grade dysplasia, and colon cancer. The data were statistically analyzed. Results: 1. Patients with diabetes show a higher incidence of polyps with high-grade dysplasia/carcinoma – 32/91 (35.16%) in comparison to patients without diabetes – 136/885 (15.37%), P < 0.001; 2. Patients with diabetes show a higher incience of polyps with cancer – 9/91 (9.89%) as compared to patients without diabetes – 18/885 (2.03%), P < 0.001. 3) Colorectal cancer occurred significantly more often in uncontrolled diabetes (P = 0.022). Conclusion: The conducted study shows a significant association between type 2 diabetes and the incidence of colorectal adenomas. These findings may lead to a conclusion that diabetic patients are at a higher risk of developing colorectal cancer, thus are in higher need for controlled colonoscopy. Therefore, it may be worth considering a scheme for screening patients in the above-mentioned group with colonoscopy.

Źródło:

Polish Journal of Surgery; 2019, 91, 4; 9-12
0032-373X
2299-2847

Pojawia się w:

Polish Journal of Surgery

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 30.

Tytuł:

Obesity-diabetes-endocrinopathy – the metabolic connection

Autorzy:

Kozakowski, Jarosław
Dudek, Piotr
Zgliczyński, Wojciech

Powiązania:

https://bibliotekanauki.pl/articles/2216797.pdf

Data publikacji:

2022-12-30

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

diabetes
endocrinopathy
hypogonadism
insulin resistance
obesity

Opis:

Introduction and aim. The article outlines the mechanisms of interrelationships between obesity, type 2 diabetes, and certain disorders of the endocrine system. The paper explains how insulin resistance develops, which is a key link between obesity and several related disorders, how hypercortisolemia leads to the development of obesity and glucose intolerance, why thyroid dysfunctions are bidirectionally associated with metabolic disturbances, in what way excessive body weight leads to the hypogonadism in men, or how menopause promotes the development of abdominal obesity, carbohydrate intolerance and, in some cases type 2 diabetes. Material and methods. Scientific articles were reviewed by searching for information using the online database with scientific articles, including PubMed, Google Scholar and other available scientific databases. Analysis of the literature. The huge prevalence of obesity, diabetes, and hormonal disorders (e.g., autoimmune thyroid disease, female and male hypogonadism) over the contemporary world together with the serious health consequences of these conditions makes up a specific triangle of metabolic connections, increasingly absorbing the human, organizational and financial resources of health systems. Conclusion. Recognizing the relationship between the components of this triangle and understanding the risks arising from this phenomenon may allow to effectively reduce its impact on our health.

Źródło:

European Journal of Clinical and Experimental Medicine; 2022, 4; 459-469
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 31.

Tytuł:

The importance of obesity and carbohydrate metabolism disorders on the course of gastroesophageal reflux disease – a pilot study

Autorzy:

Pardak, Piotr
Filip, Rafał
Krzaczek, Maciej

Powiązania:

https://bibliotekanauki.pl/articles/2203254.pdf

Data publikacji:

2022-05-31

Wydawca:

Gdański Uniwersytet Medyczny

Tematy:

obesity
gastroesophageal reflux disease
diabetes mellitus

Opis:

BackgroundCarbohydrate metabolism disorders, obesity and a severe course of gastroesophageal reflux correlate with more frequent development of esophageal complications. The aim of this study was to assess the influence of obesity and carbohydrate disorders on the characteristics of gastroesophageal reflux disease (GERD).Material and methodsThe study included 58 patients with excess weight. Anthropometric parameters (including the body mass index, BMI), data regarding GERD (severity of symptoms, gastroscopy and esophageal pH monitoring results) were included in the study. Correlations between obesity and GERD parameters were analyzed. Subjects were divided into a diabetic and a control group and the severity of GERD was compared.ResultsGERD was diagnosed in 40 patients and occurred more frequently in the obese group (73%) than in the overweight group (57%). Increased GERD severity was associated with increased BMI only for postprandial parameters. GERD was diagnosed in most of the group with carbohydrate disorders (78% vs 63% in the non-diabetic group). No differences in the severity of GERD were observed between groups depending on carbohydrate disorders.ConclusionsIn our study, GERD was common in obesity and in diabetic disorders. Increased severity of postprandial reflux was associated with an increased BMI. Diabetic disorders were not associated with more severe GERD.

Źródło:

European Journal of Translational and Clinical Medicine; 2022, 5, 1; 17-26
2657-3148
2657-3156

Pojawia się w:

European Journal of Translational and Clinical Medicine

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 32.

Tytuł:

High-density lipoprotein (HDL) cholesterol - more complicated than we think?

Autorzy:

Nessler, K.
Windak, A.
Grzybczak, R.
Nessler, M.B.
Siniarski, A.
Gajos, G.

Powiązania:

https://bibliotekanauki.pl/articles/2081847.pdf

Data publikacji:

2018

Wydawca:

Instytut Medycyny Wsi

Tematy:

cardiovascular disease
diabetes mellitus
dysfunctional HDL

Opis:

Introduction and objective. There are some clinical situations where a high level of HDL cholesterol (HDL-C) may be unfavourable. In these situations, HDL-C may undergo some changes, and even if its quantity is within the reference range, its quality is no longer the same. Brief description of state of knowledge. Diabetes is the state of elevated oxidative stress. Studies conducted to-date have revealed an increased production of the reactive forms of oxygen as the result of tissue damage in diabetes patients. The expression ‘dysfunctional HDL’ has been coined in the literature to describe high-density lipoproteins that lose their antioxidative and anti-inflammatory properties, that is, HDL-C that loses its basic functions. Recent observational studies have confirmed that the atheroprotective activity of properly functioning HDL-C is frequently impaired in clinical situations associated with oxidative stress. The presented review lays the foundation for a new approach to understanding how the functional properties of HDL help reduce cardiovascular risk. Conclusions. In the light of presented findings it seems that there is a need to seek a better diagnostic marker than HDL-C level. This study presents some possible directions for future research to bring us closer to the full understanding of the HDL particle and its role in patients with ischemic heart disease and type 2 diabetes.

Źródło:

Annals of Agricultural and Environmental Medicine; 2018, 25, 3; 517-526
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 33.

Tytuł:

Awareness among nursing students about care for children with type 1 diabetes
Dziecko z cukrzycą typu 1 w świadomości studentów pielęgniarstwa

Autorzy:

Ławnik, A.
Pańczuk, A.
Kubińska, Z.

Powiązania:

https://bibliotekanauki.pl/articles/2053561.pdf

Data publikacji:

2019

Wydawca:

Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej

Tematy:

diabetes
child
care
cukrzyca
dziecko
opieka

Opis:

Background. Diabetes, due to its prevalence and the rapid increase in the number of new incidences, has been recognized as an epidemic of the 21st century. It is estimated that over 3 million people in Poland currently suffer from this disease. According to the Ministry of Health, the knowledge of the society about diabetes is too little and insufficient. The aim of the study was to investigate and present general and expert knowledge of nursing students about type 1 diabetes, taking into account the needs of a child and the specialist skills required to care for diabetic children. Material and methods. The study was conducted among the students of nursing at Pope John Paul II State School of Higher Education in Biała Podlaska. A questionnaire designed by the author was used in this study. Results. The respondents reported that they possess basic knowledge about type 1 diabetes and at the same time are willing to learn more. They recognize that a child with type 1 diabetes requires special support, therefore medical personnel, educators and physical education teachers should have relevant knowledge and skills about care for type 1 diabetic children. Conclusions. The majority of the students surveyed had a basic knowledge and skills enabling them to provide assistance to children with type 1 diabetes and are familiar with their needs. The significance of physical activity in the life of a child with type 1 diabetes was known to a lesser extent. The students surveyed are willing to broaden their knowledge about type 1 diabetes.
Wprowadzenie. Cukrzyca z racji częstości występowania i szybkiego wzrostu liczby nowych zachorowań została uznana za epidemię XXI wieku. Szacuje się, że aktualnie w Polsce choruje ponad 3 mln ludzi. Zdaniem Ministerstwa Zdrowia wiedza społeczeństwa na temat cukrzycy jest zbyt mała i niewystarczająca. Celem pracy było zbadanie i przedstawienie wiedzy ogólnej i specjalnej studentów pielęgniarstwa na temat cukrzycy typu 1 z uwzględnieniem potrzeb dziecka oraz umiejętności umożliwiających pomoc choremu dziecku. Materiał i metody. Badania przeprowadzono wśród studentów kierunku pielęgniarstwo Państwowej Szkoły Wyższej im. Papieża Jana Pawła II w Białej Podlaskiej. W badaniach zastosowano autorski kwestionariusz ankiety. Wyniki. Badani ocenili, iż posiadają podstawową wiedzę na temat cukrzycy typu 1, a jednocześnie są chętni ją pogłębić. Przyznają, że dziecko z cukrzycą typu 1 wymaga szczególnego wsparcia, dlatego personel medyczny, pedagodzy oraz nauczyciele wychowania fizycznego powinni posiadać wiedzę i umiejętności z zakresu cukrzycy typu 1. Wnioski. Badani studenci w zdecydowanej większości posiadają podstawową wiedzę i umiejętności umożliwiające pomoc dziecku z cukrzycą typu 1 oraz znają potrzeby chorego dziecka. Zdrowotne znaczenie aktywności fizycznej w życiu dziecka z cukrzycą typu 1 jest znane badanym w mniejszym zakresie. Badani studenci zgłaszają chęć poszerzenia swojej wiedzy na temat cukrzycy typu 1.

Źródło:

Health Problems of Civilization; 2019, 13, 4; 248-253
2353-6942
2354-0265

Pojawia się w:

Health Problems of Civilization

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 34.

Tytuł:

Estimating the confidence interval of the regression coefficient of the blood sugar model through a multivariable linear spline with known variance

Autorzy:

Islamiyati, Anna
Raupong, Raupong
Kalondeng, Anisa
Sari, Ummi

Powiązania:

https://bibliotekanauki.pl/articles/2019723.pdf

Data publikacji:

2022-03-15

Wydawca:

Główny Urząd Statystyczny

Tematy:

confidence interval
diabetes
known variance
spline

Opis:

Estimates from confidence intervals are more powerful than point estimates, because there are intervals for parameter values used to estimate populations. In relation to global conditions, involving issues such as type 2 diabetes mellitus, it is very difficult to make estimations limited to one point only. Therefore, in this article, we estimate confidence intervals in a truncated spline model for type 2 diabetes data. We use a non-parametric regression model through a multi-variable spline linear estimator. The use of the model results from the irregularity of the data, so it does not form a parametric pattern. Subsequently, we obtained the interval from beta parameter values for each predictor. Body mass index, HDL cholesterol, LDL cholesterol and triglycerides all have two regression coefficients at different intervals as the number of the found optimal knot points is one. This value is the interval for multivariable spline regression coefficients that can occur in a population of type 2 diabetes patients.

Źródło:

Statistics in Transition new series; 2022, 23, 1; 201-212
1234-7655

Pojawia się w:

Statistics in Transition new series

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 35.

Tytuł:

Factors associated with poor glycaemic control in type 2 diabetic elderly patients with mild cognitive impairment

Autorzy:

Gorska-Ciebiada, M.
Ciebiada, M.

Powiązania:

https://bibliotekanauki.pl/articles/2098566.pdf

Data publikacji:

2021

Wydawca:

Instytut Medycyny Wsi

Tematy:

diabetes mellitus
elderly
mild cognitive impairment

Opis:

Introduction and objective. Recently, data has indicated a higher incidence of mild cognitive impairment (MCI) in patients with diabetes. Old age is a risk factor for cognitive deterioration and dementia. The aim of the study was to find the factors associated with poor glycaemic control in type 2 diabetic elderly patients with MCI. Materials and method. A cross-sectional study was conducted on 87 diabetic patients with MCI in an outpatient clinic. All subjects were screened for MCI using the Montreal Cognitive Assessment (MoCA). Detailed medical history and collection of blood test samples were performed. Results. 83.9% of participants had poor glycaemic control. A positive correlation was found between HbA1c level and number of visit to a doctor per year, number of co-morbidities, duration of T2DM, triglycerides and fasting glucose level; and a negative correlation between HbA1c level and years of education, HDL cholesterol level and MoCA score. The univariate logistic regression models revealed factors which are associated with poor glycemic control are: less years of education, higher no of visit to doctor per year, increased number of co-morbidities, presence of CVD, retinopathy, higher levels of triglycerides and fasting glucose, lower level of HDL cholesterol, lower MoCA score. Multivariable model revealed that higher plasma levels of fasting glucose and triglycerides are significant predictors. Conclusions. There is a high prevalence of poor glycemic control patients among elderly diabetics with MCI. Higher plasma levels of fasting glucose and triglycerides seems to be the most important predictors of poor glycemic control, however father larger studies are needed to elucidate these relationships.

Źródło:

Journal of Pre-Clinical and Clinical Research; 2019, 13, 4; 143-149
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 36.

Tytuł:

Diabulimia – a diagnostic and therapeutic challenge in the emergency department

Autorzy:

Atriham, Adan R.
Kleszczyński, Jacek
Sierakowska, Alicja
Springer, Janusz

Powiązania:

https://bibliotekanauki.pl/articles/33778957.pdf

Data publikacji:

2024-03-22

Wydawca:

Gdański Uniwersytet Medyczny

Tematy:

diabetes
eating disorders
emergency department
diabulimia

Opis:

Diabulimia is the intentional omission or reduction of insulin administration in a patient with insulin-dependent diabetes mellitus (IDDM) and coexisting eating disorder in the attempt to reduce or avoid weight gain. Although the true incidence of diabulimia is unknown, it is estimated that between 20-30% of girls and up to 40% young women with IDDM have experienced diabulimia since their diagnosis of IDDM was made. Patients with diabulimia frequently present to the emergency department, therefore early recognition of the eating disorder and prompt psychiatric consultation are essential. The aim of this review article is to summarize the existing literature about diabulimia and to raise awareness amongst emergency physicians about how to identify and treat these patients.

Źródło:

European Journal of Translational and Clinical Medicine; 2024, 7, 1; 57-62
2657-3148
2657-3156

Pojawia się w:

European Journal of Translational and Clinical Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 37.

Tytuł:

Diabetyk w pracy : realne zagrożenia i mity związane z pracą osób chorych na cukrzycę
People with diabetes at work : real threats and myths

Autorzy:

Łastowiecka-Moras, E.
Bugajska, J.

Powiązania:

https://bibliotekanauki.pl/articles/181021.pdf

Data publikacji:

2017

Wydawca:

Centralny Instytut Ochrony Pracy

Tematy:

cukrzyca
diabetyk
miejsce pracy
hipoglikemia
kontrola cukrzycy w miejscu pracy
edukacja w cukrzycy
diabetes
diabetic
workplace
hypoglycemia
diabetes control in the workplace
education in diabetes

Opis:

Cukrzyca jest chorobą metaboliczną o złożonej i różnorakiej etiologii, która charakteryzuje się stanem przewlekłego, podwyższonego poziomu glukozy we krwi. Typ 2 cukrzycy stanowi około 90% wszystkich przypadków tej choroby. Cukrzyca jest chorobą cywilizacyjną, dotykającą osób coraz młodszych, dlatego też wraz ze wzrostem liczby nowych przypadków zwiększają się koszty nie tylko diagnostyki i leczenia cukrzycy i jej powikłań, ale i koszty wynikające z przedwczesnego zaprzestania działalności zawodowej, a także bezrobocia, które dotyka osoby chorujące. Diabetycy często mają problem ze znalezieniem odpowiedniego zajęcia, a ci, którzy pracują boją się utraty pracy ze względu na powszechnie panujące, a nieprawdziwe przekonanie dotyczące ich częstszej absencji w pracy czy niższej wydajności. Wykonywanie pracy zawodowej przez diabetyka jest zalecane i korzystne i tylko nieliczne zawody są niewskazane. Aby pracownik z cukrzycą mógł bezpiecznie pracować, należy stworzyć mu odpowiednie warunki pracy, a edukacja na temat cukrzycy musi dotyczyć wszystkich – nie tylko samego pacjenta, lecz także jego rodzinę, znajomych oraz współpracowników.
Diabetes is a metabolic disease with complex and varied etiology characterized by chronic elevated level of glucose in the blood. Type 2 diabetes accounts for about 90% of all cases of the disease. Diabetes is a civilization disease, affecting a person younger and younger, and therefore with an increase in the number of new cases of the disease increase not only costs of the diagnosis and treatment of diabetes and its complications, but also the costs resulting from premature cessation of employment and unemployment, which affects people suffering from diabetes. Diabetics often have trouble with finding the appropriate job and those who work are afraid of losing their jobs because of the false belief about their frequent absenteeism and lower productivity. Performance of work by a diabetic is recommended and beneficial, and only a few professions are not recommended for them. To employee with diabetes can safely work, you must create it with adequate working conditions and education in diabetes must apply to all - not only the patient but also his family, friends and co-workers.

Źródło:

Bezpieczeństwo Pracy : nauka i praktyka; 2017, 2; 12-15
0137-7043

Pojawia się w:

Bezpieczeństwo Pracy : nauka i praktyka

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 38.

Tytuł:

Type 2 diabetes risk factors among the unemployed

Autorzy:

Filarski, R.

Powiązania:

https://bibliotekanauki.pl/articles/2052270.pdf

Data publikacji:

2014

Wydawca:

Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej

Tematy:

unemployment
type 2 diabetes
risk factors

Opis:

Unemployment is a significant social problem which has numerous negative health consequences. Findings of numerous researches provide  data on the range of the consequences of unemployment with risk of health deterioration being one of the most important. Unemployment remains an area of interest for the following fields of science: psychology, economics, sociology. More and more researches prove that there is a link between the increase of disease occurrence and death rate and long-term unemployment. Both in Poland and all over the world a steady increase in the incidence of type 2 diabetes is being observed. World Health Organization (WHO) estimates that, taking into consideration present dynamics of changes, in 2025 there will be 300 million people diagnosed with diabetes. That is why a diabetes epidemic is such a topical issue, and according to some epidemic data this epidemic is starting to reach Poland as well. Data provided by IDF (International Diabetes Federation) show that in Poland the percentage of diabetes patients is 9,1% of the whole population and it is a little higher than the European average (8,6%). It is predicted that by 2015 the percentage will rise to 11%. Identification of adverse health behaviors and introducing actions promoting health in a given population group can prove to be beneficial for the present condition of members of a given group as well as decrease the risk connected with the occurrence of diseases associated with the progress of civilization in the future. The aim of the article is to indicate type 2 diabetes risk factors among the unemployed in Poland.

Źródło:

Health Problems of Civilization; 2014, 08, 4; 4-8
2353-6942
2354-0265

Pojawia się w:

Health Problems of Civilization

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 39.

Tytuł:

Guidelines for the use of physical activity in children with type I diabetes

Autorzy:

Niewiadomska, Monika
Radziyevska, Mariya
Radziyevsky, Pavlo

Powiązania:

https://bibliotekanauki.pl/articles/1054629.pdf

Data publikacji:

2013

Wydawca:

Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego

Tematy:

insulin
physical exercise
type 1 diabetes

Opis:

Type 1 diabetes is a metabolic disorder whose treatment depends not only on the administration of insulin and diabetic control, but also on properly applied physical activity to improve insulin sensitivity and thus the patient’s condition. In order to fulfill this role, physical exercise must be systematic and properly administered. An adequate intensity depends on the physical fitness level of the patient, which may be determined in a six-minute walk test. Before a training cycle, the patient should be subjected to basic clinical tests. The intensity of training may be determined by the Karvonen or Strunz formula to precisely specify the training heart rate (60–75% of maximum heart rate, depending on the condition of the individual). Blood sugar levels should be measured before and after the training session, while during exercise a heart rate monitor should be used. All these measures should help prevent the occurrence of adverse effects such as hypoglycemia.

Źródło:

Central European Journal of Sport Sciences and Medicine; 2013, 1, 1; 47-52
2300-9705
2353-2807

Pojawia się w:

Central European Journal of Sport Sciences and Medicine

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 40.

Tytuł:

Coexistence of type 1 diabetes mellitus and spinal muscular atrophy in an 8-year-old girl: a case report

Autorzy:

Borkowska, Anna
Jankowska, Agnieszka
Szlagatys-Sidorkiewicz, Agnieszka
Sztangierska, Beata
Liberek, Anna
Plata-Nazar, Katarzyna
Kamińska, Barbara

Powiązania:

https://bibliotekanauki.pl/articles/1039156.pdf

Data publikacji:

2015

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

Spinal muscular atrophy
diabetes mellitus
children

Opis:

The spinal muscular atrophy is a rare autosomal recessive genetic disease characterized by the progressive loss of muscular strength. In its natural course the disease leads to death. Diabetes mellitus type 1 is an autoimmune metabolic disorder characterized by the disturbed insulin synthesis. This is a case report of an 8-year-old girl suffering from Werdnig Hoffman disease in whom DM1 was diagnosed. The unspecific clinical manifestation and diagnostic difficulties are presented in this paper. To the authors' knowledge, this is the first publication concerning the co-existence of these two medical conditions.

Źródło:

Acta Biochimica Polonica; 2015, 62, 1; 167-168
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 41.

Tytuł:

Autoimmunity markers in subjects with diabetes

Autorzy:

Litwińczuk-Hajduk, Joanna
Bernat-Karpińska, Małgorzata
Kowrach, Marek
Cielecka-Kuszyk, Joanna
Piątkiewicz, Paweł

Powiązania:

https://bibliotekanauki.pl/articles/972601.pdf

Data publikacji:

2016

Wydawca:

Instytut Medycyny Wsi

Tematy:

diabetes
anty-GAD
ANA
ASMA
APCA

Opis:

Introduction. Diabetes is a growing social and epidemiological problem. Accordingly, the incidence of complications associated with diabetes can cause a persistent high percentage of diseases of the cardiovascular system, kidney and nervous systems, and impaired vision. Objective. The aim of the study was to evaluate the incidence of immunological markers in patients with type 1 diabetes and those with type 2 diabetes: the anti-GAD, ANA, AMA, ASMA, APCA and LKM, compared to healthy people. Another objective of the study was to evaluate the correlation between their presence and the degree of metabolic control in both groups. Materials and methods. The study comprised 100 subjects aged 25–75 years with a body mass index (BMI) between 20–30 kg / m2, hospitalized in the Department of Internal Diseases, Diabetology and Endocrinology, at the Medical University of Warsaw, with previously diagnosed diabetes who were assigned to one of 2 groups (50 subjects with type 1 diabetes and 50 subjects with type 2 diabetes). The control group consisted of 21 healthy individuals without the diagnosis of diabetes and a prediabetic state. All the study participants had the examined antibodies determined along with the panel of biochemical tests and neurological examination for diabetic neuropathy and fundus examination. Results. Anti-GAD antibodies were present in both groups of patients. Their presence was found in 30% of people with type 1 diabetes and in 16% of people with diabetes type 2. The presence of ANA antibodies was found in 24% of people with type 1 diabetes and 22% of people with type 2 diabetes. There was no correlation between the presence of ANA antibodies ANA and duration of diabetes. In the group of patients with type 1 diabetes, there was a correlation between the presence of ANA and the incidence of diabetic polyneuropathy. ASMA and APCA antibodies occurred with equal frequency in both studied groups (4% vs. 10%). There were no antibodies of AMA or anti-LKM in any of the patients. Conclusions. Marking of ANA antibodies in patients with type 1 diabetes may be a marker used to isolate a group of patients at risk of developing diabetic neuropathy. The presence of anti-GAD in type 2 diabetes may be a LADA marker which specifically marks the group of patients with type 2 diabetes, in whom there is a faster metabolic death of beta cells. The current classification of diabetes is vague, and in the near future it should be modified based on specific patient characteristics, phenotypic appearance, as well as the results of additional tests. Determination of antibodies AMA, ASMA, APCA and anti-LKM does not seem to be significant in the diagnosis of diabetes and its chronic complications.

Źródło:

Journal of Pre-Clinical and Clinical Research; 2016, 10, 1; 28-33
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 42.

Tytuł:

Zmiany w zapisie EKG u chorych na cukrzycę zakwalifikowanych do operacji pomostowania aortalno-wieńcowego
ECG changes in diabetes patients qualified for coronary artery bypass grafting surgery

Autorzy:

Brazevic, S.
Grajek, M.
Kopyciuk, T.

Powiązania:

https://bibliotekanauki.pl/articles/261379.pdf

Data publikacji:

2015

Wydawca:

Politechnika Wrocławska. Wydział Podstawowych Problemów Techniki. Katedra Inżynierii Biomedycznej

Tematy:

CABG
EKG
cukrzyca
BMI
ECG
diabetes

Opis:

Praca przedstawia wyniki analizy statystycznej danych uzyskanych podczas badania EKG w grupie pacjentów chorych na cukrzycę i zakwalifikowanych do operacji CABG (pomostowanie aortalno-wieńcowe), a także analizę wskaźnika BMI w przebadanej grupie. Na podstawie wyników uzyskanych w badaniu EKG sprawdzano, jaki sposób leczenia cukrzycy typu 1 lub 2 ma korzystniejszy wpływ na stan pacjenta i proces rekonwalescencji. Ponadto dodatkowym celem było określenie istotnych statystycznie zmian patologicznych w zapisie EKG oraz sprawdzenie, czy związane z nimi choroby, takie jak zawał mięśnia sercowego czy nadciśnienie tętnicze, mają również negatywny wpływ na stan pacjenta. Uzyskane wyniki analizy EKG w grupie pacjentów chorych na cukrzycę mają charakter poznawczy, stanowią tylko część przeprowadzonego badania pacjentów z zaawansowaną chorobą niedokrwienną serca i mogą być podstawą wykonania dalszych, bardziej dokładnych badań.
Results of the statistical analysis ECG signals of diabetes patients qualified for CABG (coronary artery bypass grafting), as well as an analysis of BMI in the studied group, are presented. Basing on ECG analysis, the influence of the treatment methods of diabetes type 1 or 2 on patient’s condition and convalescence process, were studied. Furthermore, an additional goal was to determine statistically significant pathological changes in ECG and verification if associated diseases, such as myocardial infarction and hypertension also have a negative impact on the patient's condition. ECG analysis in case of patients with diabetes may be a part of further extended research on patients with advanced coronary artery.

Źródło:

Acta Bio-Optica et Informatica Medica. Inżynieria Biomedyczna; 2015, 21, 3; 177-184
1234-5563

Pojawia się w:

Acta Bio-Optica et Informatica Medica. Inżynieria Biomedyczna

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 43.

Tytuł:

Glucagonoma as a rare case of neuroendocrine tumor of the pancreas: a case report

Autorzy:

Zińczuk, J.
Lewoniewska, S.
Zaręba, K.
Pryczynicz, A.
Guzińska-Ustymowicz, K.

Powiązania:

https://bibliotekanauki.pl/articles/1918859.pdf

Data publikacji:

2019-08-26

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

Glucagonoma
pancreas
neuro-endocrine tumor
diabetes

Opis:

Introduction: Glucagonoma is a rare neuroendocrine tumor with characteristic features such as the presence of the glucagon-producing tumor, diabetes, and necrolytic migratory erythema. Case presentation: the 60-year-old patient was admitted to hospital with periodic pain in the right and middle upper abdominal appearing after eating. Laboratory tests presented a high glucose level and anemia. Tumor of the body and tail of the pancreas passing the organ pouch has been found during the surgery. Diagnosis of glucagonoma was confirmed in histopathological examination in immunohistochemical stainings: a positive reaction was observed with chromogranin, synaptophysin and CEA. The proliferative activity of Ki-67 was less than 1%. Staining for glucagon also was positive so confirmed the presence of neuroendocrine tumor - glucagonoma. Conclusions: Glucagonoma sometimes may occur without characteristic features which may cause delayed diagnosis. Early diagnosis of glucagonoma is important because it increases the chances of successful recovery.

Źródło:

Progress in Health Sciences; 2019, 1; 169-173
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 44.

Tytuł:

Relationship between sociodemographic factors and depression symptoms and level of diabetes acceptance

Autorzy:

Cyuńczyk, A.
Misiak, B.
Lewko, K.
Dziekońska, M.
Lewko, J.

Powiązania:

https://bibliotekanauki.pl/articles/1918889.pdf

Data publikacji:

2019

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

Diabetes
glycemic control
depression
disease acceptance

Opis:

Introduction: Diabetes is a disease whose course is strongly determined by self-monitoring and self-care. Ensuring metabolic control of diabetes is not only important for the current state of health, it also allows to maintain the body in the best condition despite the existing chronic disease. Purpose: To assess the relationship between sociodemographic factors and depression symptoms and the level of disease acceptance in diabetes. Materials and methods: The study used a diagnostic survey method with a questionnaire, the Beck Depression Inventory, and the Acceptance of Illness Scale. The study group consisted of 43 women (51%) and 41 men (49%). A total of 67% of respondents had diagnosed type 2 diabetes, 24% type 1 diabetes, and 6% LADA. Average disease duration was 15 years. Results: In the studied group, 15% of patients had diagnosed symptoms of depression; while according to the Beck Depression Inventory, depressive episodes occurred more often in mild (30%) and moderate (23%) severity. They were observed more often in people over 50 years old. Depression symptoms were significantly more common in the group of overweight and obese people (p=0.022, r(X,Y)=0.2490). Conclusions: The problem of depression increases with disease duration. People diagnosed with type 2 diabetes have lower levels of disease acceptance. Disease acceptance is a factor that eliminates the occurrence of depressive disorders of varying severity.

Źródło:

Progress in Health Sciences; 2019, 2; 21-28
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 45.

Tytuł:

Wpływ stylu zachowania na jakość życia chorych z cukrzycą, poziom samoopieki oraz parametry kliniczne
The influence of behaviour upon the quality of the life of patients with diabetes, the level of self-care and clinical parameters

Autorzy:

Fibich, Ewa

Powiązania:

https://bibliotekanauki.pl/articles/2119896.pdf

Data publikacji:

2019-01-08

Wydawca:

Europejskie Centrum Kształcenia Podyplomowego

Tematy:

cukrzyca
styl zachowania
diabetes
behavioural style

Opis:

Wstęp. Przewlekła hiperglikemia w cukrzycy wiąże się z występowaniem odległych powikłań, zaburzeniami funkcji i niewydolnością niektórych narządów, szczególnie oczu, nerek, serca oraz powikłaniami ze strony układu nerwowego i naczyń krwionośnych. Cukrzyca występuje z różnym natężeniem we wszystkich rasach, populacjach i w każdym wieku. Cel pracy. Uzyskanie odpowiedzi na następujące pytania: 1. Jaki wpływ ma styl zachowania na jakość życia chorych z cukrzycą? 2. Jaki wpływ mają typy zachowań na poziom samoopieki pacjentów z cukrzycą? 3. W jaki sposób styl zachowania wpływa na parametry kliniczne? Materiał i metody. Badanie zostało przeprowadzone wśród 100 pacjentów z cukrzycą w przedziale wiekowym 18–85 lat, leczonych w Klinice Endokrynologii, Diabetologii i Leczenia Izotopami we Wrocławiu. W badanej grupie 40 osób było leczone insuliną, 27 – doustnymi środkami hipoglikemizującymi, 23 – terapią skojarzoną, a 10 osób – tylko dietą. Narzędziami wykorzystanymi do badań były dwa kwestionariusze autorskie oraz analiza dokumentacji medycznej. Wyniki. Po analizie przeprowadzonych badań stwierdzono, że styl 1, dezadaptacyjny, skoncentrowany na unikaniu reprezentuje 20 osób; styl 2, dezadaptacyjny, skoncentrowany na przeżywanie emocji i bierność reprezentują 33 osoby; styl 3, zorientowany na rozwiązanie problemu prezentuje 35 osób; styl 4, zorientowany na poszukiwanie najlepszego rozwiązania problemu reprezentuje 12 osób. W zależności od stylu pacjenci wykazują różne postawy wobec walki z chorobą. Wnioski. Przeprowadzone badanie uwidoczniło zróżnicowanie w postrzeganiu choroby w zależności od stylu zachowania. Jednocześnie analizując wyniki badań, pokazano, że styl zachowania wpływa na jakość życia chorych z cukrzycą, na poziom samoopieki oraz na parametry kliniczne.
Background. Chronic hyperglycemia in diabetes is related with long- -term complications, functional disorder and insufficiency of some organs, in particular eyes, kidneys, heart and complications related to the nervous system and blood vessels. Diabetes occurs with the different intensity in all races, populations and at every age. Objectives. The goal of the paper is to present answers to the following questions: 1. What influence does the behavioural style exert upon the quality of life of patients having diabetes? 2. What influence do types of behaviour exert upon the level of self-care of patients having diabetes? 3. How does the behavioural style influence clinical parameters? Material and methods. The research was conducted among 100 patients having diabetes within the age between 18 and 85, treated in the Clinic of Endocrinology, Diabetology and Isotope Therapy in Wrocław. In the researched group 40 patients received insulin treatment, 27 patients received oral hypoglycemic drugs, 23 patients received the combination therapy, 10 patients were treated only with the diet. The research methods embraced two questionnaires created by the researcher and an analysis of the medical documentation. Results. After conducting the analysis the following conclusions were observed: style 1. non-adaptive, focused on avoidance represented by 20 patients; style 2. non-adaptive, focused on experiencing emotions and passive approach, represented by 33 patients; style 3. focused on problem-solving, represented by 35 patients; style 4. focused on finding the best solution of the problem, represented by 12 patients. Depending on the style patients show different attitudes to the fight with the disease. Conclusions. The research showed differences in perceiving the illness in relation to the behavioural style. The analysis made it clear that the behavioural style influences the quality of life of patients suffering from diabetes, the level of the self-care and clinical parameters.

Źródło:

Współczesne Pielęgniarstwo i Ochrona Zdrowia; 2019, 8, 1; 10-14
2084-4212

Pojawia się w:

Współczesne Pielęgniarstwo i Ochrona Zdrowia

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 46.

Tytuł:

Selected Physical Fitness Parameters in Individuals with Type 2 Diabetes Mellitus and Apparently Healthy Controls: A Comparative Cross-Sectional Study

Autorzy:

Ogunlana, Michael O.
Lateef, Ramon O.
Oyewole, Olufemi O.
Raimi, Taiwo H.
Alimi, Talayo J.
Adesina, Olubiyi
Odole, Adesola C.
Faniyi, Oluwatimilehin
Ayodeji, Ayomikun F.
Adebimpe, Busayo D.
Afolabi, Wasiu
Adepoju, Modinant O.
Ogunsola, Bose F.

Powiązania:

https://bibliotekanauki.pl/articles/39824761.pdf

Data publikacji:

2022

Wydawca:

Politechnika Opolska. Wydział Wychowania Fizycznego i Fizjoterapii

Tematy:

Fitness
Evaluation
Cardio-respiratory
Physical
Diabetes

Opis:

Objective: The study aimed to compare the physical fitness of subjects with type 2 diabetes mellitus (ST2DM) and apparently healthy non-diabetic controls (NDC). Methods: Thirty-two ST2DMs and 32 NDCs were recruited for a comparative cross-sectional study. Flexibility, balance, power, and strength were assessed using sit-up and sit and reach (SR), one leg stand, horizontal jump (HJ), and hand grip tests, respectively. Cardiovascular endurance was assessed using Vo2max estimated with a 6-minute walk test. Also, body composition was estimated using body mass index (BMI), waist circumference (WC), hip circumference (HC), waist-hip ratio (WHR), and percent body mass. Data were analyzed using descriptive and inferential statistics. The alpha level was set at p < 0.05. Results: Static balance was significantly higher in the NDCs (11.1 ± 12.6 vs 5.5 ± 5.0 sec; p = 0.047) than in the ST2DMs. Hand (34.6 ± 19.9 vs 23.6 ± 12.7 kg; p = 0.001) and leg (122.4 ± 42.8 vs 26.5 ± 43.9 cm; 0.001) strength/power were significantly higher in the NDC group compared with the ST2DM. The SR test, a measure of flexibility, was significantly higher in the NDC (SDM = 12.2 ± 19.8cm, NDC = 35.3 ± 8.8cm, p = 0.001). BMI (28.7 ± 4.3 vs 26.4 ± 41kgm-2; p = 0.048), WC (104.2 ± 8.0 vs 94.2 ± 8.7cm; p = 0.001) and WHR (1.0 ± 0.6 vs 0.9 ± 0.7; p = 0.001) were significantly higher in the ST2DM than in the NDC. There was no significant difference in the estimated VO2max between the subject group and the control group. Conclusion: Balance, flexibility, and strength were significantly lower, while measures of adiposity are significantly higher in subjects with type 2 diabetes mellitus compared with non-diabetic controls.

Źródło:

Journal of Physical Education & Health - Social Perspective; 2022, 11, 19; 13-22
2084-7971

Pojawia się w:

Journal of Physical Education & Health - Social Perspective

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 47.

Tytuł:

LADA Diabetes as a Hybrid Disease – a Narrative Review
Cukrzyca LADA jako choroba hybrydowa – przegląd literatury

Autorzy:

Mataczyńska, Anna
Paprocki, Michał
Jurgiel, Jan
Majdowski, Maciej
Wrzosek, Kamil
Lis, Michał

Powiązania:

https://bibliotekanauki.pl/articles/30146459.pdf

Data publikacji:

2023

Wydawca:

Uczelnia Łazarskiego. Oficyna Wydawnicza

Tematy:

LADA
type 1 diabetes
type 2 diabetes
autoimmune diseases
cukrzyca typu 1
cukrzyca typu 2
choroby autoimmunologiczne

Opis:

Latent autoimmune diabetes in adults (LADA) is a common hybrid disease because it combines features of both type 1 and type 2 diabetes. It is a slow-onset autoimmune disease characterized by an initial relative insulin deficiency. Studies to date indicate a clear genetic overlap between LADA and type 1 diabetes. This is related to the variants in the human leukocyte antigen (HLA) region, which encodes main histocompatibility antigens (MHC). Main histocompatibility antigens are responsible for immunoregulatory processes that are impaired in both type 1 diabetes and LADA, leading to immune system disturbances in individuals. Autoantibodies against pancreatic islets are produced, serving as key markers for distinguishing type 1 diabetes and LADA. They are characterized by occurring at a lower level, as a result of which the destruction of the immune system progresses much more slowly. In the etiopathogenesis of this disease, environmental factors and lifestyle play a significant role, which are also associated with the pathogenesis of type 2 diabetes. In most LADA cases, hyperglycemia does not reach levels as high as in type 1 diabetes, whith contributes to the misdiagnosis of it as type 2 diabetes. So far, an optimal treatment for LADA has not been established. Currently, the proposed treatment focuses on achieving good glycemic control and preventing or delaying the onset of complications. Some authors suggest that this effect can be achieved through the early use of insulin as the first-line pharmacotherapy. Emerging oral hypoglycemic agents used in other types of diabetes may also have a role in the treatment of this condition. Hereby, we discuss the possible usage of Continuous Glucose Monitoring (CGM) in this entity for precise real-time control of blood glucose levels. Despite their many advantages, it is important to remember that these systems still require a certain level of user engagement.
Cukrzyca typu LADA (latent autoimmune diabetes in adults) to powszechna choroba o postaci hybrydowej, która łączy w sobie cechy zarówno cukrzycy typu 1, jak i 2 [1]. Jest to choroba autoimmunologiczna rozwijająca się powoli i charakteryzująca się początkowo względnym niedoborem insuliny. Dotychczasowe badania wskazują na genetyczne nakładanie się cukrzyc typu LADA i typu 1. Ma to związek z wariantami w regionie ludzkich antygenów leukocytarnych (human leukocyte antigen, HLA), które kodują główne antygeny zgodności tkankowej (main histocompatibility antigens, MHC) [2, 3, 4]. Antygeny te odpowiadają za procesy immunoregulujące, które zarówno w cukrzycy typu 1, jak i typu LADA są nieprawidłowe, w wyniku czego dochodzi do zaburzeń w obrębie układu odpornościowego. W przebiegu cukrzycy typu LADA wytwarzane są autoprzeciwciała przeciwko wyspom trzustkowym, które są kluczowymi markerami służącymi do rozpoznawania cukrzyc typu 1 oraz typu LADA [5]. Występują one w dość niskim mianie, w wyniku czego destrukcja układu odpornościowego postępuje stosunkowo wolno. Zaobserwowano również, że w etiopatogenezie cukrzycy typu LADA istotne znaczenie wykazują czynniki środowiskowe i styl życia, które również związane są z patogenezą cukrzycy typu 2 [6]. U większości osób z cukrzycą typu LADA hiperglikemia nie osiąga tak dużych wartości, jak w cukrzycy typu 1, co wpływa na błędne rozpoznanie jej jako cukrzycy typu 2. Dotychczas nie ustalono optymalnego leczenia cukrzycy typu LADA, a proponowane leczenie opiera się na próbach uzyskania dobrej kontroli glikemii oraz zapobieganiu lub opóźnianiu wystąpienia powikłań. Efekt ten według niektórych autorów może być uzyskany poprzez wczesne stosowanie insuliny jako pierwszej linii farmakoterapii. Swoje miejsce w leczeniu tej jednostki chorobowej mogą także znaleźć pojawiające się na rynku doustne preparaty hipoglikemizujące stosowane w innych typach cukrzycy. W pracy została poruszona kwestia wykorzystania systemów ciągłego monitorowania glikemii (continuous glucose monitoring, CGM). Służą one do precyzyjnego kontrolowania poziomu glukozy we krwi w czasie rzeczywistym. Mimo ich wielu zalet należy jednak pamiętać, że systemy te nadal wymagają pewnego poziomu zaangażowania użytkownika.

Źródło:

Review of Medical Practice; 2023, XIX, 4; 72-77
2956-4441
2956-445X

Pojawia się w:

Review of Medical Practice

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 48.

Tytuł:

Evaluation of neutrophil phagocytic, complement functions, and cytokines expression among diabetic patients in Abuja, Nigeria

Autorzy:

Babandina, Musa Muhammad
Mainasara, Abdullahi Suleiman
Bakare, Mustapha
Emeribe, Anthony Uchenna
Shuwa, Halima Ali
Haruna, Shamsuddeen
Muhammad, Aminu Said
Abdullahi, Idris Nasir

Powiązania:

https://bibliotekanauki.pl/articles/454973.pdf

Data publikacji:

2019

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

diabetes mellitus
effector molecules
pro-inflammatory markers

Opis:

Introduction. Inflammatory response in Diabetes Mellitus (DM) begins with chronic sub-clinical inflammations as a result of insulin resistance and activation of both innate and adaptive immune system as the disease progresses to complicated diabetes. Hence, the present study investigated the neutrophil phagocytic, complement function (CH50), and some cytokine profiles among diabetic and non-diabetic patients attending the National Hospital in Abuja, Nigeria. Aim. To evaluate the neutrophil phagocytic, complement function (CH50), and some cytokine profiles among post-operative septic diabetic and post-operative septic non-diabetic patients at the National Hospital in Abuja, Nigeria. Material and methods. Subjects were recruited by convenient sampling technique through interviewer-administered questionnaires. Subsequently, blood samples were collected. Fasting blood sugar (FBS) (mmol/L) was determined using glucose oxidase method. Neutrophil function test (Fmol/phag) was assayed using nitroblue tetrazolium reduction test (NBT). Hemolytic complement function (CH 50) test was conducted using serum harvested from sheep sensitized with human group (ORh D +ve) red blood cells. While serum Interleukin-4, -6, -10 and TNF- α were determined using Enzyme Linked Immunosorbent Assay (ELISA). Results. Mean ± Standard deviation (SD) of FBS concentration of 10.5 ± 1.3 (mmol/|L) among diabetic and 4.7 ± 0.9 (mmol/L) among non-diabetics was recorded. There is a decrease in neutrophil phagocytic function with a mean ± SD of 5.4 ± 2.1 (Fmol/ phag) in diabetics compared to 9.2 ± 2.1 (Fmol/phag) in non-diabetics. Similarly, complement (CH 50) function and C-reactive protein were significantly lower in diabetics when compared to non-diabetics (p<0.001). There was a significant difference in IL-6 concentration between diabetics and non-diabetics groups, but no significant difference was observed in TNF-α, IL-4 and IL-10 concentrations between study groups (p>0.05). TNF-α and IL-6 was significantly higher in diabetics with cardiovascular disorders compared to non-diabetics subjects with cardiovascular disorders (p<0.001). Conclusion. Findings from this study revealed the association of complement, neutrophil phagocytic function, CRP and IL-6 among septic diabetic patients,. In addition TNF-α and IL-6 expression was higher in DM patients with cardiovascular disorders.

Źródło:

European Journal of Clinical and Experimental Medicine; 2019, 3; 229-235
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 49.

Tytuł:

The seven-year epidemiological study of legal abortion caused by heart disease, blood disorders, diabetes and hypertension as referred to forensic medicine centers in Fars Province

Autorzy:

Ghodrati, Fatemeh
Saadatmand, Narjes
Gholamzadeh, Saeid
Akbarzadeh, Marzieh

Powiązania:

https://bibliotekanauki.pl/articles/552001.pdf

Data publikacji:

2019

Wydawca:

Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych

Tematy:

heart diseases
diabetes mellitus
hypertension
abortion
legal.

Opis:

common risk factors for high risk pregnancies and spontaneous or therapeutic abortions. Objectives. To investigate the legal abortion caused by heart disease, blood disorders, diabetes and hypertension as referred to forensic medicine centers in Fars Province from 2007 to 2013. Material and methods. In a retrospective, cross-sectional study, samples consisted of all documents of people referred to forensic medicine centers in Shiraz since 2007 to 2013, comprising of 1664 files. Data collection tools included a demographic forum and the checklist of abortion causes. SPSS.16.0 was applied to analyze the data through descriptive statistical analysis. Results. The most frequent age group was 25–29 years at 31.5% (n = 522) and the lowest was over 40 years old at 4.15% (n = 70). The statistical report of the reasons for legal abortion permission were 19% (n = 63), 24.4% (n = 81), 10.54% (n = 35), and 8.13% (n = 27) due to heart problems, blood disorders, hypertension, and diabetes mellitus, respectively. Most frequent legal abortion permits by forensic medicine due to maternal causes were between the years of 2011–2012 at 17.8–28% (n = 59–93). The relationship between legal abortion permission at The Forensic Medicine Center at different years and maternal ages was statistically significant (p < 0.00001). Conclusions. The most common prevalent reason of abortion was Blood Disorder – 81 patients (24.4%) and heart disease – 63 cases (19%). It is essential that family education and prevention of repeated pregnancies be done with high-risk women. Also, initiation of pregnancy care at lower gestational age in identifying risky pregnancies and timely control of complications must also be undertaken

Źródło:

Family Medicine & Primary Care Review; 2019, 1; 23-29
1734-3402

Pojawia się w:

Family Medicine & Primary Care Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 50.

Tytuł:

Endophthalmitis following cataract surgery in diabetic patients

Autorzy:

Maya-Sapira, Hanapi
Koh, Yi-Ni
Azhany, Yaakub
Zunaina, Embong
Khairy-Shame, Sonny-Teo
Liza-Sharmini, Ahm ad Tajuddin
Draman, Nani
Noordin, Zamri

Powiązania:

https://bibliotekanauki.pl/articles/552628.pdf

Data publikacji:

2017

Wydawca:

Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych

Tematy:

endophthalmitis
cataract surgery
diabetes mellitus
Streptococcus mitis.

Źródło:

Family Medicine & Primary Care Review; 2017, 4; 431-436
1734-3402

Pojawia się w:

Family Medicine & Primary Care Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 51.

Tytuł:

EFFECTS OF VITAMIN D3 AND RESVERATROL ON MEMORY AND LEARNING IMPAIRMENT IN MICE WITH STREPTOZOTOCIN INDUCED DIABETES

Autorzy:

Kukula, Osman

Powiązania:

https://bibliotekanauki.pl/articles/895350.pdf

Data publikacji:

2019-06-28

Wydawca:

Polskie Towarzystwo Farmaceutyczne

Tematy:

diabetes
memory
vitamin D3
resveratrol
learning

Opis:

This study was conducted for investigating the effects of chronically administered vitamin D3 and resveratrol, which has antioxidant properties, on memory and learning impairment caused by streptozotocin-induced diabetes. Saline was administered to the mice in the first group. Streptozotocin (60 mg/kg, i.p.) was given to the mice in the second group for 3 consecutive days and no treatment was performed. Vitamin D3 (800 IU/kg, i.p.) was given to the streptozotocin-induced hyperglycemic mice in the third group for 4 weeks. Resveratrol (40 mg/kg, i.p.) was given to the streptozotocin-induced hyperglycemic mice in the fourth group for 4 weeks. Then, passive avoidance test was applied to the mice. A significant difference was found between DM+Vit D3 group (21.6±1.7, n=7) and diabetic control group (28±2.6, n=7) in the acquisition test (p<0.001). A similar result was observed between diabetic-resveratrol group (23.7±2.5, n=7) and the untreated diabetic mice group (28±2.6, n=7). There was a significant difference. 4-week vitamin D3 (400 IU/day, i.p.) and 4-week resveratrol (40 mg/kg, i.p.) treatments given to streptozotocin-induced diabetic mice were observed to significantly improved the passive avoidance acquisition and retention times. These results show the positive effects of vitamin D3 on memory.

Źródło:

Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 3; 563-568
0001-6837
2353-5288

Pojawia się w:

Acta Poloniae Pharmaceutica - Drug Research

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 52.

Tytuł:

Investigation of phytochemicals and in vivo antidiabetic evaluation of leaves and bark of Engelhardtia colebrookiana Lindl.

Autorzy:

Faisal, Muhammad
Mushtaq, Waheeda
Isthtiaq, Muhammad
Qadeer, Mohammad

Powiązania:

https://bibliotekanauki.pl/articles/1178253.pdf

Data publikacji:

2018

Wydawca:

Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN

Tematy:

Diabetes
Engelhardtia colebrookiana
Glucose
Medicinal Plant
Rabbits

Opis:

Diabetes mellitus is a complex metabolic disorder resulting from either insulin insufficiency or insulin dysfunction. Diabetes mellitus affects most of the people in both developed and developing countries. The treatment of diabetes with synthetic drugs is costly and chances of side effects are high. Phytomedicine has been used since ancient times in various parts of the world where access to modern medicine is limited. Present study was designed to check the anti-diabetic activity of methanolic extract of Engelhardtia colebrookiana L. locally known as samma or samna on Alloxan induced diabetic rabbits. Animals were divided into five groups. Group I: In this group rabbits were considered as normal control. Group II: In this group rabbits was considered as diabetic control. Group III: In this group rabbits were given by Glucophage. Group IV: In this group rabbits were given by oral dose of 1g of methanolic extract of Engelhardtia colebrookiana’s bark per day. Group V: In this group rabbits were given oral dose of 1g of methanolic extract of Engelhardtia colebrookiana’s leaves per day. The leaves extract significantly reduces the blood glucose level and body weight along with these it was found very effective in improving serum insulin level as compared to other groups and no side effect was observed in the rabbits during treatment.

Źródło:

World Scientific News; 2018, 91; 99-110
2392-2192

Pojawia się w:

World Scientific News

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 53.

Tytuł:

Amatorskie nurkowanie pacjentów z rozpoznaną cukrzycą
Diabetic patients who are amateur divers

Autorzy:

Ługowska, D.
Ługowski, T.
Krzywińska, O.
Kozakiewicz, M.
Grzelakowski, P.

Powiązania:

https://bibliotekanauki.pl/articles/1359563.pdf

Data publikacji:

2018

Wydawca:

Polskie Towarzystwo Medycyny i Techniki Hiperbarycznej

Tematy:

cukrzyca
nurkowanie amatorskie
diabetes mellitus
recreational diving

Opis:

Cukrzyca to „epidemia XXI wieku”, szacuje się, że w 2011 roku na cukrzycę chorowało 6,7% populacji Polski, z czego jedna czwarta nie miała świadomości choroby. Tak duże rozpowszechnienie cukrzycy sprawia, że coraz więcej lekarzy staje przed problemem prawidłowej kwalifikacji pacjenta z cukrzycą do amatorskiego uprawiania sportu, w tym nurkowania. W niniejszej publikacji przedstawiono najważniejsze informacje dotyczące oceny ryzyka, dopuszczenia do amatorskiego nurkowania pacjentów z cukrzycą oraz proponowanych protokołów postępowania przed i podczas uprawiania tego sportu.
Diabetes is an "epidemic of the 21st century" and it is estimated that in 2011 6.7% of Poland's population suffered from diabetes, one quarter of which was unaware of the disease. Such a high prevalence of diabetes mellitus results in an increasing number of physicians being confronted with the problem of qualifying patient with diabetes to partake in amateur sports, including diving. This publication presents the most important information concerning risk assessment, admission of diabetic patients to amateur diving and some proposed protocols of management before and during sport practice.

Źródło:

Polish Hyperbaric Research; 2018, 3(64); 39-44
1734-7009
2084-0535

Pojawia się w:

Polish Hyperbaric Research

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 54.

Tytuł:

Levels of interleukin-2 in patients with colon cancer and diabetes type 2

Autorzy:

Bosek, Irina
Sulich, Agnieszka
Rabijewski, Michał
Kaleta, Beata
Kniotek, Monika
Miłek, Tomasz
Piątkiewicz, Paweł

Powiązania:

https://bibliotekanauki.pl/articles/972606.pdf

Data publikacji:

2016

Wydawca:

Instytut Medycyny Wsi

Tematy:

diabetes type 2
colon cancer
interleukin-2

Opis:

Introduction and objective: The risk of development colon cancer (CC) is increased significantly among patients with the type 2 diabetes (T2DM). A mechanism responsible for the higher prevalence of CC among diabetic patients may be associated with the immunity system. The aim of this study is to point out the differences in the immunity state in terms of interleukin 2 level among patients with T2DM suffering from CC, and patients without these diseases Material and Methods: 79 patients were included the tests, divided into 4 groups: Group 1–23 people with T2DM, Group 2–23 people with large intestine CC, Group 3–10 people with large CC and T2DM, and Group 4–23 people without T2DM or CC. Each patient had a colonoscopy and those with cancer were confirmed in a histopathological examination. Laboratory measurements included fasting glucose, insulin, C-peptide. The concentration of interleukin-2 in serum was determined with the immunoenzymatic (ELISA) method. Results: The results obtained showed that in patients with T2DM and CC the concentration of interleukin-2 was statistically higher than in the other groups.(4.21±1.61 pg/ml vs. Group 1 -1.64±0.44 pg/ml, Group 2–1.54±0.21 pg/ml, and Group 4–1.70±0.36 pg/ml; p<0.05). Insulin levels, C-peptide and HOMA-IR did not differ significantly between groups, but a tendency was observed to higher values of HOMA-IR and insulin levels in the groups with T2DM alone and T2DM with concomitant CC. Conclusions: The data show differences in the immunity state of patients with T2DM and CC, compared with people without those two diseases. Elevated level of interleukin 2 found in this group, after confirmation in other studies with more patients, could be used as a marker of an increased risk of CC in people with T2DM

Źródło:

Journal of Pre-Clinical and Clinical Research; 2016, 10, 1; 1-5
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 55.

Tytuł:

Salivary glands dysfunction and oral manifestations in diabetes and obesity - review

Autorzy:

Garbowska, M.
Kurek, K.
Żendzian-Piotrowska, M.
Bartłomiej Łukaszuk, B.

Powiązania:

https://bibliotekanauki.pl/articles/1918605.pdf

Data publikacji:

2018-06-18

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

Diabetes
obesity
hyperglycemia
oral complications
co-morbitidities

Opis:

Diabetes mellitus (DM) is a group of metabolic disorders of multiple etiologies characterized by hyperglycemia. In 2014 it affected approximately 422 million individuals worldwide. Unfortunately, it is associated with a set of co-morbidities that contribute to a significantly reduced, i.e. 5-10 years, life expectancy. The following review will discuss the most common long-term complications of diabetes. For practical reasons we decided to narrow our interests to its very widespread, even 90-95% of the cases, form - type 2 diabetes mellitus. During the discussion particular emphasis will be placed on the salivary glands function since previous investigation has confirmed its relation to many burdensome oral diseases, while the effective medical care over diabetic patients requires better understanding of pathomechanisms of its (i.e. diabetic) oral manifestations.

Źródło:

Progress in Health Sciences; 2018, 8(1); 130-140
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 56.

Tytuł:

Parents awareness of type 1 diabetes: knowledge status

Autorzy:

Çınar, Derya
Binay Yaz, Şeyda

Powiązania:

https://bibliotekanauki.pl/articles/1918971.pdf

Data publikacji:

2021-06-14

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

Family
children
parent
type 1 diabetes
nursing

Opis:

Purpose: Type 1 diabetes is a common disease in children and teenagers, but it can occur at any age. This study aimed to determine the awareness and knowledge of type 1 diabetes in parents' to diagnose early. Materials and methods: This study is a descriptive type. Data were collected from 1 April to 1 July 2020 date in Turkey. The study sample consisted of 214 parents who accepted to participate in the study and completed the questionnaire were included in the sample. Results: It was found that the knowledge level of the parents participating in the study about type 1 diabetes was close to medium level (6.10±1.89). The study's findings revealed that there are misperceptions about the incidence of type 1 diabetes in parents. Parents are often confused about the reasons for type 1 and type 2 diabetes. Conclusions: In this study, although the knowledge level of the parents about type 1 diabetes is close to medium level, it is below the intermediate level. It is important and necessary for families to know about type 1 diabetes and its symptoms, observe their child or children and diagnose the disease early.

Źródło:

Progress in Health Sciences; 2021, 11(1); 97-103
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 57.

Tytuł:

Arterial stiffness can predict cardiorespiratory fitness in type 2 diabetic patients?

Autorzy:

Italiano Monteiro, Clara
Polaquini Simões, Rodrigo
Domingues Heubel, Alessandro
Donisete da Silva, Claudio
Ricci, Paula Angélica
Petronilho, Ariane
Borghi-Silva, Audrey
Gonçalves Mendes, Renata

Powiązania:

https://bibliotekanauki.pl/articles/2049182.pdf

Data publikacji:

2022-03-30

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

augmentation index
cardiorespiratory fitness
type 2 diabetes

Opis:

Introduction and aim. Arterial stiffness (AS) has been associated with reduced cardiorespiratory fitness (CRF). The aim of this study was to verify if there is a relationship between augmentations index (AIx), as an index for AS assessment, and CRF in individuals with type 2 Diabetes Mellitus (T2DM). Material and methods. Observational cross-sectional study including 32 individuals diagnosed with T2DM who performed two evaluations: 1. Arterial stiffness assessment using SphygmoCor and 2. CRF throughout a cardiopulmonary exercise test on a treadmill ergometer. Oxycon Mobile® device was used to obtain oxygen uptake consumption at peak (V˙O2peak); oxygen uptake efficiency slope (OUES) determined by linear regression in reason of the logarithmic transformation of the ventilation and V˙O2 obtained every minute of exercise test. Statistical analysis comprised Pearson’s Correlation and linear regression analysis performed in SigmaPlot. Results. There was a significant correlation between AS and CRF: AIx and OUES; AIx@75 and; OUES. In linear regression, AIx was determinant for V˙O2peak and OUES – AIx and; AIx@75 and V˙O2peak. Conclusion. AS was associated with CRF in individuals with T2DM. These results contribute to the body of evidence linking arterial functional properties to CRF and suggests greater attention for this important index.

Źródło:

European Journal of Clinical and Experimental Medicine; 2022, 1; 28-35
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 58.

Tytuł:

Sztuczna trzustka - stan obecny i prognozy
Artificial pancreas - present and prediction

Autorzy:

Marcinkowska, M.
Wyrodek, K.
Żórawski, P.
Łagan, S.

Powiązania:

https://bibliotekanauki.pl/articles/98930.pdf

Data publikacji:

2010

Wydawca:

Politechnika Śląska. Katedra Biomechatroniki

Tematy:

sztuczna trzustka
implant
cukrzyca
artificial pancreas
diabetes

Opis:

Cukrzyca jest chorobą cywilizacyjną spowodowaną nieprawidłowym funkcjonowaniem trzustki, dotykającą coraz większy procent społeczeństwa. Leczenie objawów tej groźnej choroby uzależnia pacjenta od regularnych pomiarów glukozy, zastrzyków insulinowych oraz ścisłej diety. Dlatego wiele ośrodków naukowych pracuje nad skutecznymi sposobami regulacji poziomu cukru we krwi. Szczególnie obiecujące wyniki dają tzw. sztuczne trzustki, czyli mechaniczne, biologiczne i biochemiczne obiekty, których głównym zadaniem jest zapewnienie pacjentowi przez długi czas lub na stałe odpowiedniej dawki insuliny. Dzięki trafnemu doborowi pomiaru poziomu glukozy i metod dozowania, które odgrywają ważną rolę w całym procesie leczenia, można ułatwić życie milionom ludzi.
Diabetes is a lifestyle disease, caused by abnormal funcionality of pancreas, which afflict more and more people every year. Treatment of this dangerous diseases makes patients dependant on regular glucose measurement , insulin injections and strict diet. Because of that many research facilities is trying to develope an effective way of blood sugar regulation. Particulary propitious are so called “artifficial pancreases”. They are biological, biochemical and mechanical objects, which are suppoused to stabilise blood sugar concetration for longest possible period, ultimately for life. Thanks to apposite selection of glucose measurment and posology methods, which have main role in treatment, life of millions of people can be facilitated.

Źródło:

Aktualne Problemy Biomechaniki; 2010, 4; 131-136
1898-763X

Pojawia się w:

Aktualne Problemy Biomechaniki

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 59.

Tytuł:

Study of health risks in patients with type 2 diabetes by assessing their diet
Badanie zagrożeń zdrowia pacjentów z cukrzycą typu 2 za pomocą oceny ich sposobu żywienia

Autorzy:

Grochowska-Niedworok, Elżbieta
Szczepańska, Elżbieta
Całyniuk, Beata
Kardas, Marek
Muc-Wierzgoń, Małgorzata

Powiązania:

https://bibliotekanauki.pl/articles/1038970.pdf

Data publikacji:

2012

Wydawca:

Śląski Uniwersytet Medyczny w Katowicach

Tematy:

nutrition
energy
diabetes
odżywianie
wartość energetyczna
cukrzyca

Opis:

Treating diabetes is a complex process covering proper diet, regular and moderate physical activity and medication. The basis of diet planning is to determine the energy requirements, considering the age, sex, physical activity, physiological condition, concomitant diseases and body mass of the patient. The aim of the study was to evaluate the energy value of meals consumed by patients with type 2 diabetes considering their age, sex and body mass. MATERIAL AND METHODS The study was performed three times on 100 patients, including 52 men and 48 women. It consisted in a 24-hour diet recall and performing anthropometric measures. To evaluate the energy value of meals, the Dieta 2 computer program was used, whereas the Statistica 7.1 program was used for statistical analyses purposes. RESULTS Among the men and women of all the age groups, the daily energy requirements were lower comparing to the dietary recommendations. Moreover, the energy value of individual meals was lower in comparison to the recommendations, excluding dinner which for all the age and weight groups (excluding men aged 31–50 of 90–99kg body mass and women over 75 years of age of 60–69 kg body mass) provided more energy comparing to the recommended value. The energy value of individual meals consumed by the studied patients regardless of their age, weight and body mass was lower comparing to the dietary recommendations. An improper distribution of energy in daily rations and its inadequate division in meals was noted, regardless of the age and sex of the studied subjects. CONCLUSIONS A 24-hour diet recall is an element enabling possible health risks assessment, including undernutrition, overweight or obesity in patients with type 2 diabetes.
Leczenie cukrzycy jest procesem kompleksowym i obejmuje stosowanie odpowiedniej diety, regularnej i umiarkowanej aktywności fizycznej oraz przyjmowanie leków. Podstawą planowania diety jest ustalenie zapotrzebowania energetycznego, które powinno uwzględniać wiek, płeć, aktywność fizyczną, stan fizjologiczny, współistnienie chorób oraz masę ciała pacjenta. Celem pracy była ocena wartości energetycznej posiłków spożywanych przez pacjentów z cukrzycą typu 2, z uwzględnieniem ich płci, wieku i masy ciała. MATERIAŁ I METODY Badanie zostało przeprowadzone trzykrotnie. Uczestniczyło w nim 100 pacjentów, w tym 52 mężczyzn i 48 kobiet. Składały się na nie 24-godzinny wywiad żywieniowy oraz pomiary antropometryczne. Do oceny wartości energetycznej posiłków posłużono się programem komputerowym Dieta 2, do analiz statystycznych wykorzystano program Statistica 7.1. WYNIKI Dla mężczyzn i kobiet we wszystkich grupach wiekowych dobowa podaż energii była niższa od wskazywanej w zalecaniach żywieniowych. Także wartość energetyczna poszczególnych posiłków była niższa od zalecanej, z wyjątkiem posiłku obiadowego, który we wszystkich grupach wiekowych i wagowych (poza mężczyznami w wieku 31–50 lat i masie ciała 90–99 kg oraz kobietami powyżej 75 lat i masie ciała 60–69 kg) dostarczał więcej energii od ilości rekomendowanej. Wartość energetyczna poszczególnych posiłków spożywanych przez badanych pacjentów niezależnie od ich płci, wieku i masy ciała była niższa od zaleceń żywieniowych. Stwierdzono nieprawidłowy rozkład energii zawartej w dziennej racji pokarmowej i podział jej na posiłki, niezależnie od płci i wieku badanych osób. WNIOSEK 24-godzinny wywiad żywieniowy jest elementem umożliwiającym ocenę możliwości wystąpienia zagrożeń zdrowia, w tym niedożywienia, nadwagi lub otyłości, u pacjentów z cukrzycą typu 2.

Źródło:

Annales Academiae Medicae Silesiensis; 2012, 66, 5; 15-21
1734-025X

Pojawia się w:

Annales Academiae Medicae Silesiensis

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 60.

Tytuł:

Comparative analysis of socioeconomic, behavioral and biological factors between healthy patients and patients with newly diagnosed diabetes in the Lubuskie Voivodeship

Autorzy:

Bonikowska, I.
Jasik-Pyzdrowska, J.
Szwamel, K.

Powiązania:

https://bibliotekanauki.pl/articles/2087637.pdf

Data publikacji:

2020

Wydawca:

Uniwersytet Opolski. Instytut Nauk o Zdrowiu

Tematy:

patients
type 2 diabetes mellitus
prediabetic state

Opis:

Background: The most effective way to prevent an increasing diabetic population lies in early detection of risk factors and diagnosis of carbohydrate metabolism disorders. Aim of the study: The study aimed at determining socio-economic variables, lifestyle behaviours and biological factors differentiating patients with newly diagnosed diabetes from diabetes-free individuals. Material and methods: Assessment of diabetic vs. non-diabetic individuals was performed according to the American criteria issued by the Commission on Social Determinants of Health as well as the FINDRISC form, which helps identify patients who are at risk of developing type 2 diabetes on the basis of multi-factorial determinants of its development. The research was conducted in 2018 among 1167 primary health care patients from Lubuskie Voivodeship using a diagnostic survey method which interviewed the respondents according to the FINDRISC standard questionnaire. Results: The group of healthy patients was similar to the group of patients with newly diagnosed diabetes with respect to variables such as age (p=0.713), sex (p=1), place of residence (p=1), level of education (p=0.076), professional activity (p=0.758), BMI (p=0.133), waist measurement (p=0.665), frequency of fruit and vegetables intake (p=0.572), frequency of taking hypotensive medications (p=0.176), frequency of diabetes occurrence in the family history (p=0.227) and physical activity (p=0.321). Conclusions: Early detection of carbohydrate metabolism disorders, with the use of standardised tools that assess diabetes development, appears to be essential in the prevention of this disorder. Therefore, there is a strong need to create a tool adjusted to socio-demographic factors such as geographical location, economic conditions and lifestyle. Additionally, active and massive screening for carbohydrate metabolism disorders in patients with a low risk of diabetes seems to be crucial in its prevention.

Źródło:

Medical Science Pulse; 2020, 14, 3; 55-63
2544-1558
2544-1620

Pojawia się w:

Medical Science Pulse

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 61.

Tytuł:

Osobowość młodzieży chorej na cukrzycę
The personality of adolescents with diabetes mellitus

Autorzy:

Szymańska, Sylwia

Powiązania:

https://bibliotekanauki.pl/articles/2139249.pdf

Data publikacji:

2000

Wydawca:

Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego

Tematy:

diabetes mellitus type 1
adolescents
personality traits

Opis:

The aim of this study was evaluation of personality traits’ differences between adolescents with diabetes (type 1) and their healthy peers. 100 diabetics (age 16–22,17) and 103 healthy adolescents were assessed. They completed Cattell’s the 16 Personality Questionnaire. The diabetics are significantly different from their healthy peers in a factor H (resistance-lack of resistance) and factors of the second degree – introversion–extraversion and worry–integration. Girls with diabetes are different from healthy girls in a factor C (emotionally stability–neurosis). The diabetics are less resistant to stress, have bigger difficulty in making social contacts, are more shy and anxiously. The girls with diabetes are more neurotic than the healthy girls.

Źródło:

Acta Universitatis Lodziensis. Folia Psychologica; 2000, 04; 57-65
2353-4842

Pojawia się w:

Acta Universitatis Lodziensis. Folia Psychologica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 62.

Tytuł:

Death due to rare rhinocerebral mucormycosis infection: a case report

Autorzy:

Baral, T.
Mugada, V.
Kolakota, R.K.

Powiązania:

https://bibliotekanauki.pl/articles/2088062.pdf

Data publikacji:

2019

Wydawca:

Uniwersytet Opolski. Instytut Nauk o Zdrowiu

Tematy:

Mucormycosis
Diabetes mellitus
Orbital cellulitis
amphotericin B

Opis:

Background: Rhinocerebral mucormycosis is the most common form of mucormycosis in patients with diabetes mellitus; it is linked to poor prognosis, presenting most commonly in an acute setting, mimicking symptoms of sinusitis or periorbital cellulitis. The general survival rate in chronic cases is 83%, compared to 10–35% in acute. Aim of the study: To report a death due to rhinocerebral mucormycosis in a 45-year-old male patient. Case report: In this case report a 45-year-old male presented with acute rhinocerebral mucormycosis and was admitted in a state of unconsciousness with complaints of sudden onset weakness of right upper and lower limb, motor aphasia, right facial swelling, orbital swelling, and diminished distant vision. Upon primary diagnosis of stroke, treatment started immediately. However, past medical history from patient’s attendants revealed that the patient underwent a tooth extraction procedure 20 days prior, and had since developed redness of the right eye, diminished distant vision, and swelling of the right side of the face. Pus was drained, and reports revealed orbital cellulitis with an intracranial spread. By the time of admission to hospital, the patient had abnormal lab profiles (WBC, ESR, serum creatinine), acute kidney injury, with MRI revealing rhinocerebral mucormycosis. The patient developed septic shock and died during treatment. Conclusions: Acute mucormycosis carries a high mortality rate. Pleiotropic manifestations and organ dysfunction add to the further risk of mortality. Timely diagnosis and management may increase the chances of the survival rate of the patient.

Źródło:

Medical Science Pulse; 2019, 13, 4; 40-43
2544-1558
2544-1620

Pojawia się w:

Medical Science Pulse

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 63.

Tytuł:

Correction by lisozyme of biochemical changes in periodontium of rats with Alloxane Diabetes

Autorzy:

Levitsky, A.P.
Stupak, E.P.

Powiązania:

https://bibliotekanauki.pl/articles/1032520.pdf

Data publikacji:

2014

Wydawca:

Uniwersytet Kazimierza Wielkiego w Bydgoszczy

Tematy:

alloxane diabetes
periodont
inflammation
dysbiosis
mineralization
lysozyme

Opis:

Aim. Aim of this study is to investigate gingivitis development in rats with experimentally induced diabetes mellitus type 1 and study of therapeutic and prophylactic actions lysozyme on periodontal condition. Methods. Alloxane diabetes has been induced by single injection of alloxane, in dose 100 mg/kg. A gel with lysozyme in concentration 2 mg/ml inflicted on the gum everyday. Taking out the animals from experiment performed at 21-th day. In gomogenates of gums the biochemical markers were estimated: malone dyaldegyde, elastase, urease, lysozyme, catalase. In homogenates of alveolar bone the activity of phosphatases, proteolytic activity was determined. Results. With alloxane diabetes in gum increased levels of biochemical markers of inflammation and increases the degree of disbiosis. In alveolar bone increases the activity of acid phosphatase and dropping the index mineralization. Appliques on a gum gel with lysozyme fixes the phenomenon of dysbiosis and inflammation in the gum, restores the index of mineralization in the alveolar bone. Conclusion. In the pathogenesis of periodontal disorders in diabetes mellitus plays an important role developing of dysbiosis. For prevent the development it periodontal complication need the use of lysozyme gel.

Źródło:

Journal of Health Sciences; 2014, 4, 1; 161-170
1429-9623

Pojawia się w:

Journal of Health Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 64.

Tytuł:

Polyphenols and flavonoids in the prevention and treatment of diabetes type 2

Autorzy:

Wałkuski, M.
Szwed, O.
Lendzioszek, M.
Terlikowska, K.M.

Powiązania:

https://bibliotekanauki.pl/articles/1918750.pdf

Data publikacji:

2018

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

Diabetes
diet
food
polyphenols
flavonoids
genes
alleles

Opis:

The genetic basis of diabetes is associated with genes that predispose to obesity development. There are also variants of genes that change the metabolism and distribution of glucose in the body tissues. Others regulate the lipid profile or affect insulin resistance, directly or indirectly affecting the risk of developing diabetes. Polyphenols are a group of compounds that have a protective effect on pancreatic cells. Thanks to their antioxidant activity, they protect cells against apoptosis, improve glucose metabolism and reduce hyperglycemia. The aim of the review was to discuss the mechanisms of bioactive food compounds influence on the human genome and to demonstrate their relationship between diabetes prevention and treatment.

Źródło:

Progress in Health Sciences; 2018, 8(2); 174-180
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 65.

Tytuł:

Acute cholecystitis in patients with diabetes mellitus - systematic review

Autorzy:

Łącka, Monika
Spychalski, Piotr
Dobrzycka, Małgorzata
Rostkowska, Olga
Kobiela, Jarosław

Powiązania:

https://bibliotekanauki.pl/articles/895729.pdf

Data publikacji:

2020-01-09

Wydawca:

Gdański Uniwersytet Medyczny

Tematy:

complications
Diabetes Mellitus
Cholecystitis
course of hospitalization

Opis:

Introduction: According to the WHO, an estimated 422 million people are suffering from diabetes worldwide. Among them, the incidence of cholelithiasis is higher than in the healthy population. The aim of this literature review was to summarize the available evidence about acute cholecystitis in patients with diabetes. Materials and methods: This study adhered to the PRISMA guidelines. The course of hospitalization of patients with and without diabetes who underwent cholecystectomy due to acute cholecystitis was compared. Following information was abstracted from original studies: general study information, patient characteristics, complications, and recommendations for patients with diabetes. Results: Initial search provided 1632 results. After full text assessment, 40 studies met the inclusions criteria. Operative and postoperative complication rates were significantly higher among the diabetic patients. Diabetes is a risk factor for conversion from laparoscopic to open cholecystectomy method. The authors' opinions on elective surgery before the onset of acute cholecystitis symptoms are divided. Conclusions: Diabetic patients are at greater risk of developing complications. An individualized screening and treatment approach, as well as proper preparation of the diabetic patient for an elective cholecystectomy could have a positive effect on the outcome. However, the low quality of the data from the systematic review does not allow for meta-analysis, which is why we cannot draw strong conclusions.

Źródło:

European Journal of Translational and Clinical Medicine; 2019, 2, 2; 71-79
2657-3148
2657-3156

Pojawia się w:

European Journal of Translational and Clinical Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 66.

Tytuł:

Endocrine disorders in patients with hereditary hemochromatosis

Autorzy:

Banaszkiewicz, Katarzyna
Sikorska, Katarzyna
Sworczak, Krzysztof

Powiązania:

https://bibliotekanauki.pl/articles/895739.pdf

Data publikacji:

2019-02-05

Wydawca:

Gdański Uniwersytet Medyczny

Tematy:

Diabetes Mellitus
Osteoporosis
endocrinology
iron overload
hemochromatosis

Opis:

Hereditary hemochromatosis (HH) is a rare genetic disorder, developing secondary to the accumulation of iron in tissues, which may lead to multiple organ failure. If untreated, it may result in liver cirrhosis or cardiomyopathy. The damage to the pancreas and the anterior pituitary, on the other hand, leads to a decreased production and secretion of hormones that are essential to life. Common symptoms of HH, that are distressing for patients, include joint pain, particularly involving hands and wrists, as well as the chronic fatigue syndrome. Iron overload affects the skeletal system, leading to osteoporosis. The pathological accumulation of iron in the anterior pituitary impairs the gonadotropin synthesis, resulting in reduced serum levels of testosterone in men and estrogens in women. This, however, contributes to lower bone mass. In vivo tests have also revealed that abnormal iron accumulation is related to an increased activity and number of osteoclasts, as well as the influence on the differentiation and activity of osteoblast-lineage cells. Based on a systematic review of literature, hereditary hemochromatosis (HH) will be presented as a chronic disease, affecting most of the endocrine glands.

Źródło:

European Journal of Translational and Clinical Medicine; 2018, 1, 2; 72-76
2657-3148
2657-3156

Pojawia się w:

European Journal of Translational and Clinical Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 67.

Tytuł:

The analysis of health behaviors and illness acceptance in patients with diabetes

Autorzy:

Starczewska, Małgorzata
Kujawska, Renata
Stanisławska, Marzanna
Rybicka, Anita
Grochans, Elżbieta

Powiązania:

https://bibliotekanauki.pl/articles/551609.pdf

Data publikacji:

2018

Wydawca:

Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych

Tematy:

diabetes mellitus
health
Acceptance of Illness Scale

Źródło:

Family Medicine & Primary Care Review; 2018, 4; 352-355
1734-3402

Pojawia się w:

Family Medicine & Primary Care Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 68.

Tytuł:

Infuence of HbA1c, serum lipids, blood pressure and BMI on Auditory Brainstem Response in diabetic patients

Autorzy:

Dąbrowski, Mariusz
Mielnik-Niedzielska, Grażyna
Nowakowski, Andrzej

Powiązania:

https://bibliotekanauki.pl/articles/454729.pdf

Data publikacji:

2017

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

auditory brainstem response diabetes mellitus
serum lipids

Opis:

Introduction. Impaired hearing organ function including abnormalities in auditory brainstem response (ABR) are more frequent in diabetic subjects compared to the general population. The aim of our study was to assess the impact of selected modifiable factors on ABR latencies in diabetic subjects. Material and Methods. 58 patients with type 1 and type 2 diabetes, aged <45 years, with diabetes duration <10 years, and without clinically overt hearing impairment or diabetic neuropathy, were included. In all subjects vital signs and blood samples were obtained, and ABR audiometry was performed. Results. Significantly delayed latencies in ABR were found in patients with total cholesterol <192 mg/dL, with HDL-cholesterol <49.5 mg/dL, with triglycerides >89 mg/dL, with presence of hypertension, and with systolic and diastolic blood pressure >135 and >78 mm Hg respectively. A linear correlation between triglycerides and wave I and III latencies, and between systolic blood pressure and wave III latency were revealed. A relationship between ABR latencies and HbA1c, LDL-cholesterol or BMI was not found. Conclusions. Several modifiable factors affect functioning of the retrocochlear part of the auditory pathway. If these results were confirmed in further studies, a vast area of possible therapeutic interventions to preserve hearing function in diabetic patients would become available.

Źródło:

European Journal of Clinical and Experimental Medicine; 2017, 3; 185-191
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 69.

Tytuł:

Osobowość pacjentek z cukrzycą typu 2
The personality of diabetic women

Autorzy:

Kocemba, Iwona

Powiązania:

https://bibliotekanauki.pl/articles/2139340.pdf

Data publikacji:

2003

Wydawca:

Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego

Tematy:

diabetes mellitus type 2
women
adult
personality

Opis:

The aim of this study was to estimate the relationship between personality of 66 healthy women and 66 women with type 2 diabetes. The average age of both groups was 63. I use the 16th Personality Factors Test by Cattell. A lower level of intelligence characterizes the personality of a diabetic, they are more submissive, effusive and responsible. They are calmer and more practical in their behavior. Healthy women are more self-sufficient and unconventional.

Źródło:

Acta Universitatis Lodziensis. Folia Psychologica; 2003, 07; 77-85
2353-4842

Pojawia się w:

Acta Universitatis Lodziensis. Folia Psychologica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 70.

Tytuł:

Wsparcie społeczne a kontrola poziomu cukru we krwi w cukrzycy typu 2
Social support and glycemic control in type 2 diabetes mellitus

Autorzy:

Kocemba, Iwona

Powiązania:

https://bibliotekanauki.pl/articles/2139601.pdf

Data publikacji:

2007

Wydawca:

Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego

Tematy:

diabetes mellitus
social support
HbA1c

Opis:

Diabetes is an incurable disease. Recently researchers are focusing more often on the role of the social support in diabetes treatment. It seams that support from family and friends plays a big role in the results of the disease treatment. Lack of such support may decrease patients’ treatment motivations. The aim of this study was to estimate the relationship between social support and metabolic control. The group which was examined consisted of 35 people with type 2 diabetes not treated with insulin and 31 who were on insulin. The Social Support Inventory by Saranson and glycosylated hemoglobin (HbA1c) for glycemic control were used in this study. The research indicates that poorer metabolic control was correlated with the lack of social support.

Źródło:

Acta Universitatis Lodziensis. Folia Psychologica; 2007, 11; 59-65
2353-4842

Pojawia się w:

Acta Universitatis Lodziensis. Folia Psychologica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 71.

Tytuł:

Cushing’s disease: is pasireotide LAR a breakthrough in adjuvant therapy after unsuccessful surgery?

Autorzy:

Witek, Przemysław
Mazur, Marta
Witek, Joanna

Powiązania:

https://bibliotekanauki.pl/articles/1062550.pdf

Data publikacji:

2017

Wydawca:

Medical Education

Tematy:

Cushing’s disease
corticotrophin
cortisol
diabetes
pasireotide

Opis:

Cushing’s disease is a rare endocrine disorder caused by ACTH-secreting pituitary adenoma. The treatment of choice is a transsphenoidal surgery performed by an experienced neurosurgeon. However, in some patients adjuvant treatment is required due to ineffective surgery or disease recurrence. This article discusses new aspects of pharmacological treatment of ACTH-dependent hypercortisolism in light of a recent publication reporting the efficacy and safety of once a month pasireotide LAR injections in Cushing’s disease.

Źródło:

OncoReview; 2017, 7, 4; 176-179
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 72.

Tytuł:

Stigma and its relationship with life satisfaction in patients with type 2 diabetes mellitus

Autorzy:

Turen, Sevda
Yurtsever, Melike

Powiązania:

https://bibliotekanauki.pl/articles/40418503.pdf

Data publikacji:

2024-03-30

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

life satisfaction
stigma
type 2 diabetes mellitus

Opis:

Introduction and aim. This study aims to determine the level of stigma in patients with type 2 diabetes mellitus (T2DM) and evaluate its relationship with their life satisfaction. Material and methods. This is a descriptive and cross-sectional study conducted in a single tertiary care center. Two hundred and ten patients ≥18 years old diagnosed with T2DM were included in this study. The relationship between the “Type 2 diabetes stigma assessment scale” and the “Satisfaction with life scale” was assessed using Pearson correlation analysis. Results. The average age of the participants was 54.85±15.81 years. The majority of patients reported adherence to diabetes treatment and having comorbidities. Stigma levels were higher in patients ≤65 years, those with less than a high school education, and those receiving insulin or oral anti-diabetic treatment, but lower with a T2DM diagnosis duration of ≤ 5 years (p<0.05). Life satisfaction was influenced by age, education status, economic status, adherence to treatment, dietary compliance, and the presence of comorbidities. A moderately negative relationship between stigma level and life satisfaction was identified. Conclusion. The study’s results indicate that an increase in stigma level is associated with a decrease in life satisfaction in patients with type 2 diabetes mellitus.

Źródło:

European Journal of Clinical and Experimental Medicine; 2024, 22, 1; 128-133
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 73.

Tytuł:

Świadomość pacjentów na temat późnych powikłań cukrzycy typu 2
Patients’ awareness of late complications in type 2 diabetes

Autorzy:

Antczak-Komoterska, Anna
Boruczkowska, Beata

Powiązania:

https://bibliotekanauki.pl/articles/26435320.pdf

Data publikacji:

2020

Wydawca:

Państwowa Akademia Nauk Stosowanych we Włocławku

Tematy:

cukrzyca
powikłania cukrzycy
retinopatia
neuropatia
nefropatia
kardiomiopatia
stopa cukrzycowa
diabetes
diabetes complications
retinopathy
neuropathy
nephropathy
cardiomyopathy
diabetic foot

Opis:

Wstęp. Cukrzyca to grupa chorób metabolicznych charakteryzująca się hiperglikemią wynikającą z defektu produkcji lub działania insuliny wydzielanej przez komórki beta trzustki. Najczęstszą postacią cukrzycy jest cukrzyca typu 2, w której pierwotnie dochodzi do zmniejszonej wrażliwości tkanek na insulinę (insulino oporność). Wieloletnia cukrzyca prowadzi do wielu groźnych powikłań, które dotyczą wielu narządów, np. narządu wzroku, nerek czy włókien nerwowych. Cel. Celem pracy była ocenia świadomości pacjentów na temat późnych powikłań cukrzycy typu 2. Materiał i metody. W badaniu wzięło udział 100 pacjentów zarówno płci żeńskiej jak i męskiej leczących się w Poradni Diabetologicznej CDL Barska. Wybrano metodę sondażu diagnostycznego, zastosowano technikę ankietową i analizę dokumentacji medycznej. Narzędziem badawczym wykorzystanym w pracy był autorski kwestionariusz ankiety oraz dokumentacja medyczna. Wyniki. Z przeprowadzonych badań własnych wynika, że zdecydowaną większość pacjentów stanowią kobiety (63%), powyżej 60 roku życia (40%), mieszkające w mieście (62%), aktywne zawodowo (44%), które chorowały poniżej 5 lat (45%). Najwięcej badanych wskazywało na uczestniczenie w konsultacjach okulistycznych (65%). Największa grupa badanych wskazywała na powikłanie w postaci nadciśnienia (37,4%), zaburzenie widzenia (23,7%), najmniej wskazało na stopę cukrzycową (0,7%).
Admission. Diabetes mellitus is a group of metabolic diseases characterized by hyperglycaemia resulting from a defect in the production or function of insulin secreted by the beta cells of the pancreas. The most common form of diabetes is type 2 diabetes, in which there is primarily a decreased sensitivity of tissues to insulin (insulin resistance). Long-term diabetes leads to many serious complications that affect many organs, such as the eyes, kidneys and nerve fibers. Aim. The aim of the study was to assess the patients' awareness of late complication of type 2 diabetes. Material and methods. The study involved 100 female and male patients treated at the CDL Barska Diabetes Clinic. The diagnostic survey method was selected, the survey technique and the analysis of medical records were used. The research tool used in the work was the original questionnaire and medical documentation. Results. The conducted research shows that the vast majority of patients are women (63%), over 60 (40%), living in the city (62%), professionally active (44%), who were ill for less than 5 years (45%). Most respondents indicated participation in ophthalmological consultations (65%). The largest group of respondents indicated a complication in the form of hypertension (37.4%), visual impairment (23.7%), and the least indicated a diabetic foot (0.7%).

Źródło:

Innowacje w Pielęgniarstwie i Naukach o Zdrowiu; 2020, 5, 4; 54-65
2451-1846

Pojawia się w:

Innowacje w Pielęgniarstwie i Naukach o Zdrowiu

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 74.

Tytuł:

An evaluation of the prevalence of autoimmunological diseases in patients with diabetes and obesity hospitalized in the Department of Diabetology, Rural Medicine Institute in Lublin

Autorzy:

Szcześniak, Grzegorz
Zdybel, Wojciech
Kozak-Nurczyk, Patrycja
Dziemidok, Piotr

Powiązania:

https://bibliotekanauki.pl/articles/551931.pdf

Data publikacji:

2016

Wydawca:

Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych

Tematy:

obesity
autoimmune diseases
diabetes
Hashimoto’s thyroiditis, APS.

Źródło:

Family Medicine & Primary Care Review; 2016, 3; 345-347
1734-3402

Pojawia się w:

Family Medicine & Primary Care Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 75.

Tytuł:

Koszty leczenia i prewencji cukrzycy
Costs of treatment and prevention of diabetes

Autorzy:

Jasik-Pyzdrowska, Justyna
Bonikowska, Iwona

Powiązania:

https://bibliotekanauki.pl/articles/466250.pdf

Data publikacji:

2018

Wydawca:

Uniwersytet Humanistyczno-Przyrodniczy im. Jana Długosza w Częstochowie. Wydawnictwo Uczelniane

Tematy:

koszty
terapia
prewencja
cukrzyca
costs
therapy
prevention
diabetes

Opis:

W artykule przedstawiono zagadnienie stale rosnących nakładów finansowych związanych z kosztami leczenia cukrzycy – choroby cywilizacyjnej XXI wieku. Na podstawie danych literaturowych stwierdzono dysproporcję pomiędzy kosztami prewencji oraz leczeniem powikłań cukrzycy. Problematyka profilaktyki jest dyskusyjna, głównie ze względu na jej ograniczony zasięg terytorialny oraz incydentalność, podczas gdy potrzeby są wielosektorowe i wymagają zmian systemowych.
The article presents the issue of constantly rising costs associated with the treatment of diabetes – a civilization disease of the 21st century. Based on the literature data, there was a huge disproportion between the costs of prevention and the treatment of diabetes complications. The problem of prevention is debatable, mainly due to its limited territorial coverage and incidentality, while the needs are multi-sectoral and require systemic changes.

Źródło:

Prace Naukowe Akademii im. Jana Długosza w Częstochowie. Pragmata tes Oikonomias; 2018, 12; 77-87
2300-2999

Pojawia się w:

Prace Naukowe Akademii im. Jana Długosza w Częstochowie. Pragmata tes Oikonomias

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 76.

Tytuł:

The course of glucose intolerance in children with cystic fibrosis: a retrospective study − preliminary report
Przebieg nietolerancji glukozy u dzieci z mukowiscydozą: badanie retrospektywne − doniesienie wstępne

Autorzy:

Piechowiak, Katarzyna
Trippenbach-Dulska, Hanna
Walicka-Serzysko, Katarzyna

Powiązania:

https://bibliotekanauki.pl/articles/772645.pdf

Data publikacji:

2015

Wydawca:

Wydawnictwo ALUNA

Tematy:

cystic fibrosis related diabetes
glucose monitoring
insulin
pump

Opis:

Diabetes is a common and severe complication of cystic fibrosis. If unrecognized, the condition not only causes deterioration of pulmonary function and failure to gain weight, but also a six-fold increase in mortality. Aim: 1. To evaluate the course of abnormal glucose tolerance and cystic fibrosis-related diabetes (CFRD), as well as the effects of treating these conditions in children with cystic fibrosis. 2. To analyze the association between the classes of mutations in both alleles of the CFTR gene and glucose intolerance. Materials and methods: analysis was undertaken of the clinical records of 12 children (from the years 2002 to 2014), who were under the care of the Diabetes Outpatient Clinic at the Medical University of Warsaw and the Cystic Fibrosis Centre of the Institute of Mother and Child in Warsaw. The patients were divided into groups based on glucose tolerance categories in the Oral Glucose Tolerance Test (impaired glucose tolerance - IGT, cystic fibrosis related diabetes without fasting hyperglycemia − CFRD FH(-) or with fasting hyperglycemia – CFRD FH (+)). The mean age of the children who were referred to the Diabetes Outpatient Clinic was 12.09±3.57 years and the mean HbA1c at the baseline versus the end of the follow up was 6.16±1,77% versus 6.03±1.05%, respectively. We used the continuous glucose monitoring system (CGMS) for the diagnostics of 4 patients. The mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene were investigated in all the patients. All the children had mutations in at least one allele of the CFTR gene belonging to class I or II. Six (6/12) patients were homozygous, and 3 (3/12) patients heterozygous for the Phe508del (former F508del) mutation. Three children had other mutations (1717-1G>A/2183AA-G, R553X/3380delGAAG, G542X/2143delT). Results: In our study group we recognized impaired glucose tolerance (IGT) in 7 (7/12) patients and cystic fibrosis-related diabetes (CFRD) in 5 (5/12) patients; there were 4 patients with CFRD FH(+) and 1 patient with CFRD FH(-). During follow up we observed IGT deterioration of glucose tolerance towards CFRD FH(-) in 4(4/7) patients. Eight (8/12) patients were on functional insulin therapy, five of them (5/8) used insulin pumps. The remaining patients (4 individuals - 4/12), who were in good condition and on a high-glycemic index product restricted diet, did not require insulin. In the group treated with insulin we observed improvement in BMI z-scores (from-1.14 to -0.70). Conclusions: Glucose tolerance in children with cystic fibrosis deteriorates with age. Patients in a good condition and with good compliance to a low-glycemic index product diet, start insulin therapy later. Patients with a severe course of cystic fibrosis and diabetes require immediate insulin implementation. Insulin treatment improves their nutritional status. A continuous glucose monitoring system is a useful diagnostic tool which can be taken into account in therapeutic decisions. Prospective studies on the pediatric population with cystic fibrosis are needed in Poland for a better analysis of the associations between abnormal glucose tolerance, the class of mutation in the CFTR gene and the impact of glucose intolerance treatment on the clinical status of the patients.
Cukrzyca jest częstym i ciężkim powikłaniem mukowiscydozy. Nierozpoznana nie tylko prowadzi do pogorszenia czynności płuc i słabszych przyrostów masy ciała, lecz również zwiększa 6-krotnie śmiertelność. Cel: 1. Ocena przebiegu zaburzeń tolerancji glukozy i cukrzycy u dzieci z mukowiscydozą oraz efekty ich leczenia. 2. Ocena związku pomiędzy klasą mutacji w genie CFTR i nietolerancją glukozy. Materiały i metody: Przeanalizowano retrospektywnie dokumentację medyczną 12 dzieci (z lat 2002- -2014), będących pod opieką Poradni Diabetologicznej Kliniki Pediatrii Warszawskiego Uniwersytetu Medycznego i Zakładu Mukowiscydozy Instytutu Matki i Dziecka w Warszawie. Pacjentów podzielono według kategorii zaburzeń tolerancji glukozy w teście doustnego obciążenia glukozą (nieprawidłowa tolerancja glukozy, cukrzyca związana z mukowiscydozą bez hiperglikemii na czczo, cukrzyca związana z mukowiscydozą z hiperglikemią na czczo). Średni wiek dziecka w momencie skierowania do Poradni Diabetologicznej wynosił 12,09±3,57 lat, średnia wartość HbA1c na początku i na końcu obserwacji wynosiła 6,16±1,77% versus 6,03±1,05. U 4 pacjentów w trakcie diagnostyki zaburzeń przemiany węglowodanowej zastosowano ciągły monitoring glikemii. U wszystkich dzieci oznaczono klasy mutacji w genie CFTR. Wszyscy pacjenci mieli przynajmniej w jednym allelu genu CFTR mutacje należące do I lub II klasy. Sześcioro (6/12) pacjentów było homozygotami a troje (3/12) pacjentów heterozygotami mutacji Phe508del (dawniej F508del). Troje dzieci miało inne mutacje (1717-1G>A/2183AA-G, R553X/3380delGAAG, G542X/2143delT). Wyniki: U 7 (7/12) pacjentów z badanej grupy rozpoznano nieprawidłową tolerancję glukozy, u 5 (5/12) pacjentów cukrzycę związaną z mukowiscydozą w tym u 4 pacjentów z hiperglikemią na czczo a u jednego bez hiperglikemii na czczo. W trakcie obserwacji stwierdziliśmy u 4 (4/7) pacjentów z nieprawidłową tolerancją glukozy pogorszenie jej przebiegu w kierunku cukrzycy bez hiperglikemii na czczo. U 8 (8/12) pacjentów zastosowano insulinoterapię, u większości (5/8) pacjentów przy pomocy pompy insulinowej. Pozostali pacjenci (4 osoby -4/12), którzy byli w dobrym stanie klinicznym i przestrzegali diety z ograniczeniem produktów o wysokim indeksie glikemicznym, nie wymagali insulinoterapii. U pacjentów leczonych insuliną obserwowano wzrost BMI z-scores (z -1,14 do -0,70). Wnioski: Tolerancja glukozy u dzieci z mukowiscydozą pogarsza się z wiekiem. Pacjenci w dobrym stanie klinicznym i przestrzegający diety z ograniczeniem produktów o wysokim indeksie glikemicznym wymagają insulinoterapii w późniejszym okresie. Pacjenci z ciężkim przebiegiem mukowiscydozy i cukrzycą wymagają natychmiastowej insulinoterapii. Leczenie insuliną poprawia stan odżywienia. Ciągły monitoring glikemii jest przydatnym narzędziem diagnostycznym, który należy brać pod uwagę przy podejmowaniu decyzji terapeutycznych. Prospektywne badania większej populacji pediatrycznej chorych na mukowiscydozę w Polsce są potrzebne, celem lepszego poznania związku pomiędzy zaburzeniami tolerancji glukozy, klasą mutacji w genie CFTR, wpływu metody leczenia zaburzeń tolerancji glukozy na stan kliniczny pacjentów.

Źródło:

Developmental Period Medicine; 2015, 1; 80-91
1428-345X

Pojawia się w:

Developmental Period Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 77.

Tytuł:

Biosensory elektrochemiczne - możliwości i ograniczenia komercjalizacji
Development of Commercially Successful Biosensors for Glucose

Autorzy:

Magner, E.

Powiązania:

https://bibliotekanauki.pl/articles/142647.pdf

Data publikacji:

2013

Wydawca:

Stowarzyszenie Inżynierów i Techników Przemysłu Chemicznego. Zakład Wydawniczy CHEMPRESS-SITPChem

Tematy:

biosensor elektrochemiczny
glukoza
cukrzyca
electrochemical biosensors
glucose
diabetes

Opis:

W artykule opisano właściwości i warunki rozwoju biosensorów elektrochemicznych, na przykładzie biosensorów do oznaczania glukozy. Omówiono czynniki, które mają wpływ na handlowy sukces produkcji elektrochemicznych biosensorów glukozy na dużą skalę.
The development and characterization of electrochemical biosensors is described from the perspective of the development of biosensors for the determination of glucose. The factors that have influenced the large scale commercial development of electrochemical glucose biosensors are discussed.

Źródło:

Chemik; 2013, 67, 2; 105-110
0009-2886

Pojawia się w:

Chemik

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 78.

Tytuł:

Wpływ akceptacji choroby na jakość życia pacjentów z cukrzycą typu 2
Effect of disease acceptance on the quality of life of patients with type 2 diabetes

Autorzy:

Pantlinowska, Danuta
Antczak, Anna

Powiązania:

https://bibliotekanauki.pl/articles/1030036.pdf

Data publikacji:

2016

Wydawca:

Państwowa Uczelnia Zawodowa we Włocławku

Tematy:

type 2 diabetes
quality of life
acceptance
patient

Opis:

Introduction. Type 2 diabetes is a chronic disease and its development is often asymptomatic, showing no clinical problems, but often after diagnosis it is already accompanied by the microvascular and macrovascular complications. A chronic disease changes the picture of the world, revalues the lives of most people who are forced to change their life goals. Depending on the situation, each person reacts differently to the illness. Some people accept this condition, others cannot accept the fact of the disease. Aim. The aim of the study was to identify the relationship between the acceptance by patients with type 2 diabetes, and the quality of their lives. At the same time based on the studies carried out it is possible to evaluate one’s adaptation to living with the disease. Material and methods. The study included 80 patients diagnosed with type 2 diabetes. They were the patients hospitalized in the Department of Internal Medicine and registered in the Outpatient Diabetes Health Care Centre in Chełmno. As a research tool the Quality of Life Rating Questionnaire SF-36 and AIS questionnaire were applied. The study was approved by the aforementioned institutions and the Committee on Bioethics. Results. The average point value of quality of life among the respondents was 78.64 points. This result indicates that the study group is a group with an average level of quality of life, on the border of the high level. The biggest negative impact on the quality of life of respondents came from a general feeling of health. Of all the areas of the disease acceptance, most respondents assessed the sense - I think people staying with me are often embarrassed because of my illness - average 3.74 point, and my state of health makes me not feel a fully fulfilled person - average 3.64 point. Conclusions. 1. Patients indicating a higher degree of acceptance function better in emotional and physics pheresl, and thus may be realized in the professional and social sphere. 2. Patients exhibiting a higher degree of acceptance of the disease more easily adapted to the limitations imposed by the disease. 3 Patients showing a higher degree of acceptance of the disease feel fully-fulfilled as a person.
Wstęp. Cukrzyca typu 2 jest chorobą przewlekłą, rozwija się często bezobjawowo, nie wykazując problemów klinicznych, natomiast często po rozpoznaniu towarzyszą już jej powikłania mikronaczyniowe i makronaczyniowe. Przewlekła choroba zmienia obraz świata, przewartościowuje życie większości osób, które zmuszone są do zmiany swoich życiowych celów. W zależności od zaistniałej sytuacji każdy człowiek inaczej reaguje na chorobę. Jedni ludzie akceptują ten stan, inni nie mogą pogodzić się z faktem choroby. Cel. Celem badań było wskazanie zależności między zaakceptowaniem przez pacjentów cukrzycy typu 2, a jakością ich życia. Jednocześnie na podstawie przeprowadzonych badań można ocenić przystosowanie się do życia z chorobą. Materiał i metody. W badaniach wzięło udział 80 osób ze zdiagnozowaną cukrzycą typu 2. Byli to pacjenci hospitalizowani w Oddziale Chorób Wewnętrznych i zarejestrowani w Poradni Diabetologicznej Zespołu Opieki Zdrowotnej w Chełmnie. Jako narzędzie badawcze zastosowano Kwestionariusz Oceny Jakości Życia SF-36 oraz kwestionariusz AIS. Na przeprowadzenie badań uzyskano zgodę powyższej placówki oraz Komisji Bioetycznej. Wyniki. Średni wartość punktowa jakości życia wyniosła wśród badanych - 78,64 punktu. Wynik ten wskazuje, że badane to grupa o przeciętnym poziomie jakości życia, na granicy poziomu wysokiego. Największy negatywny wpływ na poziom jakości życia badanych miało ogólne poczucie zdrowia. Ze wszystkich obszarów akceptacji choroby, najwyżej ocenili badani poczucie - myślę, że ludzie przebywający ze mną są często zakłopotani z powodu mojej choroby - średnia3,74 punktu oraz mój stan zdrowia sprawia, że nie czuję się człowiekiem pełnowartościowym - średnia 3,64 punktu. Wnioski. 1. Pacjenci wykazujący wyższy stopień akceptacji lepiej funkcjonują w sferze emocjonalnej i fizycznej, a co za tym idzie mogą realizować się w sferze zawodowej oraz społecznej. 2. Pacjenci wykazujący wyższy stopień akceptacji choroby łatwiej przystosowali się do ograniczeń narzuconych przez chorobę. 3. Pacjenci wykazujący wyższy stopień akceptacji choroby czują się ludźmi pełnowartościowymi.

Źródło:

Innowacje w Pielęgniarstwie i Naukach o Zdrowiu; 2016, 1, 4; 32-39
2451-1846

Pojawia się w:

Innowacje w Pielęgniarstwie i Naukach o Zdrowiu

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 79.

Tytuł:

Forms of Activities with a Dog as Modern Types of Physical Recreation

Autorzy:

Niewiadomska, Monika

Powiązania:

https://bibliotekanauki.pl/articles/1030579.pdf

Data publikacji:

2018

Wydawca:

Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego

Tematy:

agility
dog sports
physical activity
type 1 diabetes

Opis:

The rapid civilisational development that took place in the second half of the 20th century, and the resulting changes in the conditions and ways of people’s lives brought forth a number of social phenomena, both positive and negative. Physical activities, i.e. any forms of physical effort undertaken voluntarily in leisure time for entertainment and health purposes, contribute greatly to overcoming the dangers of modern civilization. Among these, activities with the participation of a dog are becoming increasingly popular. These activities are exercised by people of all ages in the form of dog sports, as well as for recreational and therapeutic purposes. The aim of the paper is to present various forms of activities with a dog as modern types of physical recreation exercised by people of all ages. Regular exercise with a dog greatly improves the well-being and provides a feeling of harmony and inner peace. It is becoming yet another modern form of activity.

Źródło:

Central European Journal of Sport Sciences and Medicine; 2018, 23, 3; 53-58
2300-9705
2353-2807

Pojawia się w:

Central European Journal of Sport Sciences and Medicine

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 80.

Tytuł:

Effectiveness of electrical stimulation and low-intensity laser therapy on diabetic neuropathy: A systematic review

Autorzy:

Adehunoluwa, Emmanuel A.
Adesina, Miracle A.
Adeulure, Taiwo G.
Akinfolarin, Yemi T.
Babatunde, Kazeem O.
Efunniyi, Adenike O.
Mamud, Olusola S.
Oyejola, Oluwatimilehin G.
Tiamiyu, Oluwaleke M.
Olajire, Tolulope I.

Powiązania:

https://bibliotekanauki.pl/articles/1077040.pdf

Data publikacji:

2019

Wydawca:

Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN

Tematy:

Diabetes mellitus
diabetic neuropathy
electric stimulation
laser therapy

Opis:

Diabetes mellitus (DM) is a group of metabolic diseases which typically presents with frequent urination, increased thirst and increased hunger. DM be classified into three main types: type I (insulin-dependent DM), type-II (non-insulin dependent DM) and type III (gestational DM). Diabetes is a group of diseases of global health significance as 382 million people worldwide had diabetes in the year 2013 and this was projected to increase to an estimated 415 million in 2015. Damage to the nerves of the body (diabetic neuropathy) is the most common complication of diabetes. The signs and symptoms of diabetic neuropathy include numbness, diminished sensation, pain etc. Various types of electrotherapy, such as transcutaneous electrical nerve stimulation (TENS), pulsed-dose electrical stimulation, frequency-modulated electromagnetic neural stimulation, have been reported effective in managing diabetic neuropathy. This study is a systematic review of the evidence to enable the determination of the effectiveness of electrical stimulation and low-intensity laser therapy (LILT), and also aid their recommendation if proven to be effective. The outcome of this study was that TENS and other forms of electrical stimulation reviewed in this study may be effective and safe non-pharmacological treatment modalities in relieving the symptoms associated with diabetic neuropathy. The effectiveness of LILT couldn’t be determined due to the different parameters used to evaluate patients’ outcome and limited number of studies. Authors recommend that further randomized controlled trials with similar methodological parameters and studies with higher quality of evidences are needed to establish the true effectiveness of these modalities in diabetic neuropathy.

Źródło:

World News of Natural Sciences; 2019, 23; 110-127
2543-5426

Pojawia się w:

World News of Natural Sciences

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 81.

Tytuł:

Levels of physical activity in people with diabetes residing in Spain
Niveles de actividad física en personas con diabetes residentes en España

Autorzy:

González-Carcelén, Carmen M.
Nicolás López, Jonathan
López Sánchez, Guillermo Felipe

Powiązania:

https://bibliotekanauki.pl/articles/1491126.pdf

Data publikacji:

2020-01-03

Wydawca:

Atena Research Association

Tematy:

Physical activity
Mediterranean diet
Diabetes
Diabetic retinopathy
Spain

Opis:

Objectives: The aim of this study was to analyze the level of physical activity in people with diabetes, depending on their characteristics. Methods: The sample consisted of 81 participants with type 1 and type 2 diabetes and belonging to a diabetes care association. First of all, the participants completed the short version of the International Physical Activity Questionnaire and the Mediterranean Diet Adherence Questionnaire online. Subsequently, they indicated their sex, age, type of diabetes, the presence of other complications and the years since diagnosis. In addition, data on consumption of tobacco and alcohol, glycosylated hemoglobin and fasting glucose were collected. For the analysis of the data, t-test for independent samples was used to compare means between categories, always with a level of significance of p <.05. Furthermore, effect size was calculated through Cohen’s d. Finally, the frequency and the percentage of the variables were calculated. Findings: The results showed in all the categories an average level of physical activity higher than the recommendations of physical activity for people with diabetes, being the level of physical activity predominantly moderate. Although women also complied with the recommendations for physical activity, their level of physical activity was significantly lower than the level of men Conclusions: It is recommended to expand the research on the barriers and motivations found by people with diabetes to practice physical activity, playing special attention to women with diabetes.

Źródło:

Atena Journal of Public Health; 2020, 2; 2-2
2695-5911

Pojawia się w:

Atena Journal of Public Health

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 82.

Tytuł:

Efficacy of Lepidium Sativum to act as an anti-diabetic agent

Autorzy:

Mishra, N.
Mohammed, A.
Rizvi, S.I.

Powiązania:

https://bibliotekanauki.pl/articles/1918412.pdf

Data publikacji:

2017

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

Lepidium sativum
diabetes
insulin
streptozotocin
oxidative stress
cholesterol

Opis:

Objective: Lepidium sativum, commonly known as chandrashoor in India, has been used in the Indian traditional medicine system for the treatment of various diseases. The present study was undertaken to investigate the hypoglycemic effect of Lepidium sativum in normal and streptozotocin-induced diabetic rats. Materials and methods: Thirty (30) adult male Wistar rats weighing 157±51g were randomly assigned to five groups of six rats each as Normal control, Diabetic control, Diabetics supplemented with Lepidium sativum extract, Diabetics treated with insulin, and Normal rats supplemented with Lepidium sativum. All rats were fed with a normal laboratory diet, nutrient rich pellets, and had free access to drinking water. The rats were injected with streptozotocin at a dose of 45 mg/kg body weight intraperitoneally to induce diabetes. The extracts were then given orally to different groups of rats at a dose of 20mg/kg body weight for 16 days. Thereafter, the rats were sacrificed, and blood samples collected by cardiac puncture were used for the determination of Glucose, Creatinine, Alkaline Phosphatase, Cholesterol, Malondialdehyde level, % DPPH, and FRAP content. Results: Administration of lepidium extract showed a significant reduction in glucose, creatinine, and alkaline phosphatase levels. Elevated cholesterol level was restored approximately to normal; a significant decrease in malondialdehyde levels was also observed compared to diabetic controls. Conclusion: Lepidium sativum extract shows efficacy in the prevention and management of diabetes mellitus and its related complications.

Źródło:

Progress in Health Sciences; 2017, 7(1); 44-53
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 83.

Tytuł:

Insulin initiative attitudes of type 2 diabetes individuals Turkish validity and reliability study

Autorzy:

Guleryuz, İlayda Oylum
Okçın, Figen

Powiązania:

https://bibliotekanauki.pl/articles/1918967.pdf

Data publikacji:

2021-06-14

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

Validity
reliability
nursing care
type 2 diabetes
attitudes

Opis:

Purpose: A study was conducted to investigate the Turkish Validity and Reliability of the Insulin Initiation Attitudes Scale of individuals with Type 2 diabetes. Materials and methods: This methodologically planned study was conducted with 128 Type 2 diabetes mellitus patients who met the sampling criteria. Data collected using a personal information form to identify individuals diagnosed with diabetes and CH-ASIQ, which assessed their attitudes towards diabetes, and the form Insulin Therapy Attitude Scale parallel as a parallel form. For the statistical analysis of the data, Construct Validity, Exploratory Factor Analysis, and Kaiser-Meyer-Olkin test, Confirmatory Factor Analysis, Pearson, Gutmann, Split Half, Spearman, Cronbach Alpha coefficient methods were used. Results: It was statistically significant; it is seen that 14.1% of the participants were in the 41-50 age range, 37.5% were in the 51-60 age range, and 48.8% were 61 and over. According to Kaiser-Meyer-Olkin test, the result was found to be 0.626. According to the results of factor analysis, 4 factors have emerged which have Eigenvalues above 1 and explain 69.48% of the total variance. According to Confirmatory Factor Analysis, Structural Equation Modeling Results of the scale were found to be p=0.000. According to Cronbach Alpha result 0.756. Conclusion: There was a relationship between attitudes to having information about the treatment of diabetics and attitude, and there was the relationship between them. Effects of fear, pain on these findings were observed. The importance of education for a positive attitude was determined. The importance of patients' attitudes towards insulin therapy should be emphasized for adaptation to the disease.

Źródło:

Progress in Health Sciences; 2021, 11(1); 75-82
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 84.

Tytuł:

Evaluation of the Finnish Diabetes Risk Score (FINDRISC) for diabetes screening in occupational health care

Autorzy:

Vandersmissen, Godelieve J.
Godderis, Lode

Powiązania:

https://bibliotekanauki.pl/articles/2177344.pdf

Data publikacji:

2015-04-24

Wydawca:

Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi

Tematy:

diabetes mellitus
occupational health
questionnaires
cross-sectional studies

Opis:

Objectives The objective of the study was to investigate the prevalence of undiagnosed dysglycaemia and the risk for type 2 diabetes using the Finnish Diabetes Risk Score (FINDRISC) in the working population of Belgium. Moreover, it was to evaluate performance and applicability of FINDRISC as a screening tool during occupational health surveillance. Material and Methods A cross-sectional analysis was carried out over the years 2010–2011 among 275 healthy employees who underwent a health check including fasting plasma glucose and the FINDRISC questionnaire. The sensitivity, specificity and predictive value of different FINDRISC cut-off values to detect dysglycaemia was revised in the literature and then calculated. Results The prevalence of unknown dysglycaemia was 1.8%. Twelve percent of the employees had a FINDRISC score of 12 to 14 corresponding to a moderate risk of 17% to develop diabetes within the next 10 years, and 5.5% had a score of 15 or more corresponding to a high – very high risk of 33% to 50%. All dysglycaemic individuals had a FINDRISC score of 12 or higher. The sensitivity and specificity for detecting dysglycaemia was respectively 100% and 84.1% for a FINDRISC cut-off value ≥ 12; and 80% and 95.9% for a cut-off value ≥ 15. Conclusions A considerable number of workers had dysglycaemia or was at risk for developing type 2 diabetes. The questionnaire is a reliable, valuable and easy to use screening tool in occupational health surveillance.

Źródło:

International Journal of Occupational Medicine and Environmental Health; 2015, 28, 3; 587-591
1232-1087
1896-494X

Pojawia się w:

International Journal of Occupational Medicine and Environmental Health

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 85.

Tytuł:

Assessment of the incidence rate of end-stage renal disease in patients with and without diabetes in Poland

Autorzy:

Wierzba, W.
Karnafel, W.
Tyszko, P.
Kanecki, K.
Śliwczyński, A.

Powiązania:

https://bibliotekanauki.pl/articles/2081907.pdf

Data publikacji:

2018

Wydawca:

Instytut Medycyny Wsi

Tematy:

diabetes mellitus
end-stage renal disease
incidence rate

Opis:

Introduction. Several studies have suggested, that diabetes is very important factor of the risk of the chronic a renal disease. The paper aims to present a retrospective analysis of incidence of end-stage renal disease in subgroups of patients with and without diabetes in Poland. Material and methods. For assessing this problem an electronic search was performed using Polish National Health Fund data base from 01.01.2011 until 31.12.2013 in general population and from 01.01.2012 until 31.12.2012 in 2 populations: with diabetes and without diabetes mellitus. Results. The 43.70 % patients with end-stage renal disease was diabetic. The incidence rate in 2012 was: 292.48 ± 90.97 diabetic men / 100,000 diabetic population; 203.10 ± 90.97 diabetic women / 100,000 diabetic population; 23.44 ± 6.34 non-diabetic men / 100,000 non-diabetic population; 17.88 ± 6.33 non-diabetic women / 100,000 non-diabetic population. Conclusions. The incidence rate of end-stage renal failure in diabetics was multiple times higher than the incidence rate in non-diabetics. The incidence rate of new ESRD cases in Poland estimated to be 36.17 per 100,000 of general populations in 2011, 35.28% in 2012 and 30.46 per 100,000 of general populations in 2013. In 2012, the incidence rate of new ESRD cases in male diabetics was 292.48 ± 90.97 per 100,000 of diabetes men population, and in women diabetics 203.10 ± 66.06 per 100,000 of diabetes women population. In the same 2012 year, the incidence of new ESRD cases in men non-diabetics was 3.44 ± 6.34 per 100,000 of non-diabetes, and in women non-diabetes 17.58 ± 6.33 per 100,000 of non-diabetes women population.

Źródło:

Annals of Agricultural and Environmental Medicine; 2018, 25, 3; 568-571
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 86.

Tytuł:

The role of acetylsalicylic acid and circulating microRNAs in primary prevention of cardiovascular events in patients with Diabetes Mellitus Type 2 - a review

Autorzy:

Chabior, A.
Pordzik, J.
Mirowska-Guzel, D.
Postuła, M.

Powiązania:

https://bibliotekanauki.pl/articles/2085138.pdf

Data publikacji:

2019

Wydawca:

Instytut Medycyny Wsi

Tematy:

diabetes mellitus
primary prevention
platelets
acetylsalicylic acid
microRNA

Opis:

Introduction. Type 2 diabetes mellitus (T2DM) is a common metabolic disorder, which carries a risk for atherosclerosis and cardiovascular impairment. The purpose of this review is to demonstrate the role of acetylsalicylic acid (ASA) in primary cardiovascular prevention in T2DM patients, as well as present an outline of microRNAs (miRNA) relevant to ASA therapy and should be evaluated as targets to improve treatment. Brief description of state of knowledge. Although the etiology of hypercoagulable state in T2DM is considered multifactorial, attention mainly focuses on platelet disturbances. Platelets in T2DM not only demonstrate intensified adhesion, activation, aggregation, and thrombin generation, but are likely to deliver miRNAs at specific sites of action in the cardiovascular system, hence contributing to the pathogenesis of cardiovascular events. Objective. Since cardiovascular disease (CVD) is currently the leading cause of mortality among T2DM patients, appropriate risk stratification and management is necessary to reduce morbidity and mortality in this group. A large number of T2DM patients show inadequate response to antiplatelet therapy, which currently revolves around ASA, despite compliance with treatment regimens proposed by the guidelines. Conclusions. The review shows that the use of ASA for primary prevention is beneficial in patients at high cardiovascular risk. However, it is important to select patients in whom ASA therapy will bring the most beneficial outcome with minimal risk for adverse effects. This can be potentially achieved with the use of unique biomarkers. The biologically diverse characteristics of miRNA make them a promising novel biomarker and potential tool for better risk stratification, as well as antiplatelet therapy optimization.

Źródło:

Annals of Agricultural and Environmental Medicine; 2019, 26, 4; 515-522
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 87.

Tytuł:

Quality of life of patients with type 2 diabetes in relation to method of treatment

Autorzy:

Dudzińska, M.
Tarach, J.S.
Zwolak, A.
Malicka, J.
Kowalczyk, M.
Daniluk, J.

Powiązania:

https://bibliotekanauki.pl/articles/2052362.pdf

Data publikacji:

2015

Wydawca:

Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej

Tematy:

type 2 diabetes
quality of life
insulin therapy

Opis:

Inappropriate glycaemic control in type 2 diabetes leads to long-term complication and affects length of life. Intensification of treatment, involving insulin therapy is often delayed because of fear of negative influence on quality of life (QoL). Aims: evaluation of differences on QoL with type 2 diabetes patients in relation to method of current antidiabetic treatment, especially patients who are on the threshold of insulin therapy introduction. Methods: study involved 274 patients (mean 62.2years, 55.8%F) who were divided into 3 groups: patients treated with oral anti-diabetic agents (OAD group, n=111), patients, for whom insulin was introduced (Intensification group, n=68) and patients treated with insulin (Insulin group, n=95). QoL was measured with questionnaires: EQ-5D, DQL-BCI and DSC-R. Results: There were no statistically significant differences in EQ-5D indices among studied patients (OAD group-0.82, Intensification group–0.78, Insulin group–0.75). EQ-VAS among patients switched to insulin therapy was lower than in OAD group (52.7 and 59.3, respectively, p=0.004). The differences in DQL-BCI scores among all groups of patients were statistically insignificant (scores: OAD group-56.7, Intensification group-54.8, Insulin group-51.7). DSC-R score in Intensification group was higher than among OAD group (30.9 and 25.3, respectively, p=0,08). Patients switched to insulin therapy manifested the highest level of hyperglycemia-related burden and the lowest treatment satisfaction. Conclusions: patients whose treatment was intensified reported their QoL as lower than the patients treated with OAD, however there was no significant difference found in respect of QoL between patients from the latter group and patients already treated with insulin.

Źródło:

Health Problems of Civilization; 2015, 09, 4; 26-31
2353-6942
2354-0265

Pojawia się w:

Health Problems of Civilization

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 88.

Tytuł:

Medical and socio-demographic determinants of depressive disorders in diabetic patients

Autorzy:

Florek-Łuszczki, M.
Choina, P.
Kostrzewa-Zabłocka, E.
Panasiuk, L.
Dziemidok, P.

Powiązania:

https://bibliotekanauki.pl/articles/2085636.pdf

Data publikacji:

2020

Wydawca:

Instytut Medycyny Wsi

Tematy:

diabetes
medical and socio-demographic factors
depressive disorders

Opis:

Introduction. Diabetes is a civilisation disease creating a serious challenge for public health. In Poland, approximately 2 million people suffer from diabetes, of which about 25% are unaware of their illness. A considerable part of persons with diabetes experience complications related with the disease. Objective. The aim of the study was to determine the relationship between elements of the state of health and socio-demographic characteristics of diabetic patients treated in the Diabetes Clinic at the Institute of Rural Health (IMW) in Lublin, eastern Poland, and the occurrence of depressive symptoms in these patients. Materials and method. The study was conducted in 2017–2018 among patients treated in the Diabetes Clinic at the Institute of Rural Health in Lublin, by the method of a diagnostic survey using the Beck’s Depression Inventory and an author-constructed questionnaire, as well as data from the patients’ medical records. The study included 314 patients from the Diabetes Clinic who expressed their informed consent to participate in the research. Results. The study showed that diabetes is a disease which predisposes for the occurrence of depression. The occurrence of depressive symptoms of various degrees of intensity was confirmed in more than a half of the examined patients. Among the factors which exerted a significant effect on the occurrence of depressive symptoms were: diabetic neuropathy, type 2 diabetes, high BMI value, lack of occupational activity, poor material standard, and the need to obtain assistance in daily functioning due to the fact of being ill with diabetes. Conclusions. It is necessary to implement routinely performed examinations into the diagnostic-therapeutic process to assess the state of psychological health of diabetic patients, which would allow sufficiently early application of appropriate psychological or psychiatric intervention.

Źródło:

Annals of Agricultural and Environmental Medicine; 2020, 27, 2; 255-259
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 89.

Tytuł:

Comparison of course of infections and antibiotherapy in patients with and without diabetes mellitus – one center experience
Porównanie przebiegu infekcji oraz zastosowanej antybiotykoterapii u pacjentów chorych na cukrzycę i bez cukrzycy – doświadczenie jednego centrum medycznego

Autorzy:

Stec, Maria
Suleja, Agata
Kuczmik, Wiktoria
Mroskowiak, Aleksandra
Migacz, Maciej
Holecki, Michał

Powiązania:

https://bibliotekanauki.pl/articles/21265478.pdf

Data publikacji:

2023-12-04

Wydawca:

Śląski Uniwersytet Medyczny w Katowicach

Tematy:

infekcje
terapia antybiotykowa
diabetes
infections
antibiotic therapy
cukrzyca

Opis:

INTRODUCTION: Infections affect all patients, including those with diabetes mellitus (DM), which can determine the course of infection. The aim of the study was to compare the course and treatment of infection in patients with DM and without DM. MATERIAL AND METHODS: 180 medical records of patients hospitalized in 2021 at the Department of Internal Medicine, Autoimmune and Metabolic Diseases in Katowice, with infections were analyzed. The analysis included age, sex, clinical diagnosis, DM treatment, antibiotic therapy, and laboratory parameters. The Statistica program was used for statistical analysis. RESULTS: The most prevalent reasons for hospitalization in both groups were: pneumonia in the course of COVID-19 (35.5% DM vs 33.7% non-DM) and urinary tract infections (26.3% DM vs 19.2% non-DM). Significantly more non-DM patients required polyantibiotic treatment (69.7% DM vs 89.4% non-DM). The most frequently used antibiotics were β-lactams (59.2% DM vs 57.7% non-DM). In-hospital mortality was 20% (21% DM vs 19.2% non-DM). The length of hospitalization was 1–35 days, the median in the whole group was 9 days (10 days DM vs 8 days non-DM). Both the initial and terminal CRP concentrations were analyzed. The median of the initial value was 71.6 (72.3 DM vs 66.2 non-DM) and the median of the terminal value was 17.15 (17.9 DM vs 15.3 non-DM). The glucose concentration on admission was assessed with the median 123.5 mg/dL (156 mg/dL DM vs 107 mg/dL non-DM). CONCLUSIONS: Many DM complications are well known, yet the course and treatment of infection do not differ significantly in patients with DM and without DM. Despite that, each patient should be considered individually, so the chosen treatment constitutes an optimized therapy.
WSTĘP: Zakażenia występują u wszystkich pacjentów, w tym także u chorych na cukrzycę (diabetes mellitus – DM), której współwystąpienie może jednak determinować przebieg zakażenia. Celem pracy było porównanie przebiegu i leczenia infekcji u chorych z DM i bez DM. MATERIAŁ I METODY: Analizie poddano dokumentację medyczną 180 pacjentów hospitalizowanych w 2021 r. w Klinice Chorób Wewnętrznych, Autoimmunologicznych i Metabolicznych w Katowicach z powodu infekcji. W analizie uwzględniono wiek, płeć, rozpoznanie kliniczne, metodę leczenia DM, antybiotykoterapię i parametry laboratoryjne. Do analizy statystycznej wykorzystano program Statistica. WYNIKI: Najczęstszymi przyczynami hospitalizacji w obu grupach były: zapalenie płuc w przebiegu COVID-19 (35,5% DM vs 33,7% bez DM) oraz infekcje dróg moczowych (26,3% DM vs 19,2% bez DM). Istotnie więcej pacjentów bez DM wymagało leczenia z użyciem wielu antybiotyków (69,7% DM vs 89,4% bez DM). Najczę-ściej stosowanymi antybiotykami były β-laktamy (59,2% DM vs 57,7% bez DM). Śmiertelność wewnątrzszpitalna wyniosła 20% (21% DM vs 19,2% bez DM). Czas hospitalizacji wynosił 1–35 dni, mediana w całej grupie wyniosła 9 dni (10 dni w przypadku DM vs 8 dni bez DM). Analizowano zarówno początkowe, jak i końcowe stężenie CRP. Mediana wartości początkowej wyniosła 71,6 (72,3 DM vs 66,2 bez DM), a mediana wartości końcowej 17,15 (17,9 DM vs 15,3 bez DM). Mediana stężenia glukozy przy przyjęciu wynosiła 123,5 mg/dL (156 mg/dL DM vs 107 mg/dL bez DM). WNIOSKI: Wiele powikłań DM jest dobrze znanych, jednak przebieg i leczenie infekcji nie różnią się istotnie u pacjentów z DM i bez DM. Mimo to do każdego pacjenta należy podchodzić indywidualnie, tak aby wybrane leczenie stanowiło zoptymalizowaną terapię.

Źródło:

Annales Academiae Medicae Silesiensis; 2023, 77, 1; 217-225
1734-025X

Pojawia się w:

Annales Academiae Medicae Silesiensis

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 90.

Tytuł:

Biochemical and medical importance of vanadium compounds

Autorzy:

Korbecki, Jan
Baranowska-Bosiacka, Irena
Gutowska, Izabela
Chlubek, Dariusz

Powiązania:

https://bibliotekanauki.pl/articles/1039732.pdf

Data publikacji:

2012

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

inflammation
cancer
vanadium
diabetes
insulin-mimetic action
pollution

Opis:

Vanadium belongs to the group of transition metals and is present in the air and soil contaminants in large urban agglomerations due to combustion of fossil fuels. It forms numerous inorganic compounds (vanadyl sulfate, sodium metavanadate, sodium orthovanadate, vanadium pentoxide) as well as complexes with organic compounds (BMOV, BEOV, METVAN). Depending on the research model, vanadium compounds exhibit antitumor or carcinogenic properties. Vanadium compounds generate ROS as a result of Fenton's reaction or of the reaction with atmospheric oxygen. They inactivate the Cdc25B2 phosphatase and lead to degradation of Cdc25C, which induces G2/M phase arrest. In cells, vanadium compounds activate numerous signaling pathways and transcription factors, including PI3K-PKB/Akt-mTOR, NF-κB, MEK1/2-ERK, that cause cell survival or increased expression and release of VEGF. Vanadium compounds inhibit p53-dependent apoptosis and promote entry into the S phase of cells containing functional p53 protein. In addition, vanadium compounds, in particular organic derivatives, have insulin-mimetic and antidiabetic properties. Vanadium compounds lower blood glucose levels in animals and in clinical trials. They also inhibit the activity of protein tyrosine phosphatase 1B. By activating the PI3K-PKB/Akt pathway, vanadium compaunds increase the cellular uptake of glucose by the GLUT4 transporter. The PKB/Akt pathway is also used to inactivate glycogen synthase kinase-3. The impact of vanadium compounds on inflammatory reactions has not been fully studied. Vanadium pentoxide causes expression of COX-2 and the release of proinflammatory cytokines in a human lung fibroblast model. Other vanadium compounds activate NF-κB in macrophages by activating IKKβ.

Źródło:

Acta Biochimica Polonica; 2012, 59, 2; 195-200
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 91.

Tytuł:

Factors Associated with Physical Activity in People with Diabetes

Autorzy:

Sieńko-Awieraniów, Elżbieta
Stępień-Słodkowska, Marta
Latkowska, Agnieszka
Głowacka, Ewa

Powiązania:

https://bibliotekanauki.pl/articles/1054668.pdf

Data publikacji:

2015

Wydawca:

Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego

Tematy:

Body Mass Index
diabetes mellitus
lifestyle
physical activity

Opis:

Background: Diabetes mellitus is a chronic disease related to the occurrence of numerous metabolic disorders. Their common feature is hyperglycaemia, caused by insufficient insulin secretion or its malfunction. The World Health Organization states that 346 million people worldwide have diabetes. The studies in adults with type 2 diabetes clearly demonstrate that the change of lifestyle behaviours effectively improves glycemic control. The modifications of lifestyle habits, such as regular physical activity and healthier dietary habits prove to be beneficial for patients. The aim of this study was to determine the factors affecting the level of physical activity in people with diabetes mellitus. Methods: Research material consisted of the data gathered from a diagnostic survey, which was conducted in a form of a questionnaire. The study included 60 people with type 1 or type 2 diabetes. Results: Unfortunately, the results show that not all of them were active enough, which is so crucial for stabilizing the disease. Conclusions: The diagnosis of diabetes in the respondents resulted in more time being spent by them on physical activity, which resulted in the improvement of diabetes control and the normalization of body weight according to BMI, thus increasing the effectiveness of diabetes treatment and reducing complications. The frequency of the physical activity undertaken by the respondents prior to the disease was not related to gender, however, after the diagnosis, it was dependent on gender

Źródło:

Central European Journal of Sport Sciences and Medicine; 2015, 12, 4; 73-81
2300-9705
2353-2807

Pojawia się w:

Central European Journal of Sport Sciences and Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 92.

Tytuł:

[5-(Benzyloxy)-1H-indol-1-yl]acetic acid, an aldose reductase inhibitor and PPARγ ligand

Autorzy:

Soltesova Prnova, Marta
Majekova, Magdalena
Milackova, Ivana
Díez-Dacal, Beatriz
Pérez-Sala, Dolores
Ceyhan, Muserref
Banerjee, Sreeparna
Stefek, Milan

Powiązania:

https://bibliotekanauki.pl/articles/1038997.pdf

Data publikacji:

2015

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

aldose reductase inhibitor
PPARγ ligand
diabetes
indole

Opis:

Based on overlapping structural requirements for both efficient aldose reductase inhibitors and PPAR ligands, [5-(benzyloxy)-1H-indol-1-yl]acetic acid (compound 1) was assessed for inhibition of aldose reductase and ability to interfere with PPARγ. Aldose reductase inhibition by 1 was characterized by IC50 in submicromolar and low micromolar range, for rat and human enzyme, respectively. Selectivity in relation to the closely related rat kidney aldehyde reductase was characterized by approx. factor 50. At organ level in isolated rat lenses, compound 1 significantly inhibited accumulation of sorbitol in a concentration-dependent manner. To identify crucial interactions within the enzyme binding site, molecular docking simulations were performed. Based on luciferase reporter assays, compound 1 was found to act as a ligand for PPARγ, yet with rather low activity. On balance, compound 1 is suggested as a promising lead-like scaffold for agents with the potential to interfere with multiple targets in diabetes.

Źródło:

Acta Biochimica Polonica; 2015, 62, 3; 523-528
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 93.

Tytuł:

Costs of elective vs emergency cholecystectomy in diabetic patients

Autorzy:

Łącka, Monika
Spychalski, Piotr
Obłój, Paweł
Łaski, Dariusz
Rostkowska, Olga
Wieszczy, Paulina
Kobiela, Jarosław

Powiązania:

https://bibliotekanauki.pl/articles/1196132.pdf

Data publikacji:

2020-12-03

Wydawca:

Gdański Uniwersytet Medyczny

Tematy:

diabetes
elective cholecystectomy
emergency cholecystectomy
costs of hospitalization

Opis:

Introduction: Hospitalization costs of diabetic patients are estimated to be higher than non-diabetic. Literature on the topic is however limited. The aim of this study was to compare the costs of elective and emergency cholecystectomy of diabetic and non-diabetic patients. Material and methods: A retrospective analysis involved diabetic versus non-diabetic age- and sex-matched patients who underwent emergency and elective cholecystectomy at a single center in Poland between 2016-2019. Results: The total costs of an elective cholecystectomy were 739.31 ± 423.07 USD for diabetic patients and 797.14 ± 772.24 USD for non-diabetic patients (p = 0.51). Whereas emergency cholecystectomy total costs were 3950.72 ± 2856.83 USD (diabetic patients) and 2464.31 ± 1718.21 USD (non-diabetic patients) (p = 0.04). The difference in total costs between elective cholecystectomy vs emergency cholecystectomy in both groups (diabetic vs non-diabetic patients) was statistically significant (p < 0.01 vs p < 0.05 respectively). Conclusions: In this study we demonstrated that emergency cholecystectomy is associated with a significant increase in hospitalization costs, particularly in diabetic patients. This suggests that early qualification of diabetic patients for an elective cholecystectomy could be beneficial for both diabetic patients and public health insurers.

Źródło:

European Journal of Translational and Clinical Medicine; 2020, 3, 2; 37-43
2657-3148
2657-3156

Pojawia się w:

European Journal of Translational and Clinical Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 94.

Tytuł:

Lack of association between the development and clinical course of Type 1 and Type 2 Diabetes Mellitus and rare T130I variant of the HNF4A gene in the Polish population

Autorzy:

Grzanka, Małgorzata
Matejko, Bartłomiej
Klupa, Tomasz
Malecki, Maciej T.

Powiązania:

https://bibliotekanauki.pl/articles/972570.pdf

Data publikacji:

2016

Wydawca:

Instytut Medycyny Wsi

Tematy:

diabetes
HNF4A
Thr130lle variant

Opis:

Type 2 diabetes (T2DM) is a multifactorial disease related to both environmental and genetic factors. While environmental factors leading to the development for T2DM are well established, the majority of factors responsible for the genetic background of the disease remain unknown. The aim of this study was to test whether a rare variant within the HNF4A gene, Thr130Ile (rs1800961), may influence the development of clinical course of T1DM or T2DM subjects. The analysis included 574 patients with T2DM, 207 T1DM individuals and 284 healthy controls. All subjects were genotyped for the Thr130Ile polymorphism in HNF4A. For T2DM, no differences were found in allele frequencies between cases and controls. The percentage of CT genotype in these groups were 5.7% (33 patients) and 5.6% (16 healthy controls), respectively (p=0.89). For T1DM, the allele frequency was not statistically different from T2DM or control subjects. In conclusion, no association was found between rare variant Thr130Ile of the HNF4A gene and the development of either T2DM nor T1DM in the Polish population.

Źródło:

Journal of Pre-Clinical and Clinical Research; 2016, 10, 1; 63-65
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 95.

Tytuł:

The role of temperament in the changes of coping in Type 2 diabetes: direct and indirect relationships

Autorzy:

Kroemeke, Aleksandra
Kwissa-Gajewska, Zuzanna

Powiązania:

https://bibliotekanauki.pl/articles/430728.pdf

Data publikacji:

2014-06-01

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

temperament
coping
cognitive appraisal
emotions
diabetes mellitus
mediation

Opis:

The paper investigates whether the changes in cognitive appraisal and coping strategies related to initiation of insulin treatment onset mediate the effect of temperament on changes in positivity ratio among diabetic patients. Temperament, cognitive appraisal, coping strategies and positivity ratio (ratio of positive to negative affect) were assessed among 278 patients: just before conversion to insulin therapy and then one month later. Mediation analysis indicated that endurance and briskness were directly connected to changes in positivity ratio, whilst the effect of perseveration on positivity ratio was indirect via changes in negative appraisal, emotion- and problem-focused coping. The results confirm the stressful nature of the initiation of insulin treatment, and the assumptions of Lazarus’ model of stress and regulative role of temperament.

Źródło:

Polish Psychological Bulletin; 2014, 45, 2; 240-248
0079-2993

Pojawia się w:

Polish Psychological Bulletin

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 96.

Tytuł:

The analysis of the level and trends of potential years of life lost due to diabetes in Poland in the years 2002-2013

Autorzy:

Papaj, D.
Papaj, E.
Beck, M.

Powiązania:

https://bibliotekanauki.pl/articles/1918835.pdf

Data publikacji:

2019

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

Diabetes
potential years of life lost
PYLL
trends

Opis:

Introduction: The industrial and socio-economic development is the direct cause of changes in major health threats in highly developed societies. Diabetes is a civilization disease and it depends on the impaired action of insulin. Together with its complications, it is a significant cause of deaths all over the world. Purpose: To assess the level and trends of potential years of life lost (PYLL) due to diabetes in Poland in the years 2002-2013. For specific purposes, it is necessary to assess the PYLL level and the dynamics of PYLL rates due to diabetes and comparison with all causes of death. Materials and Methods: The research material consists of data from generally available databases from the Polish Statistical Office. Potentially lost years of life were calculated using the method proposed by J-M Romeder. Premature deaths have been defined as deaths occurring before the age of 70. Trends in PYLL coefficients were generated by the computer program Joinpoint Regression Programme. Results: The results of the conducted analysis unambiguously indicate the increase in the PYLL ratio due to diabetes was observed in both the general population and the male population. The higher rate of PYLL growth and its much higher level in the male population, compared to the female population, point out to the fact that men die much younger because of diabetes. The dynamics of the PYLL coefficient trends connected with all causes of death indicate the reduction of premature mortality.

Źródło:

Progress in Health Sciences; 2019, 1; 51-59
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 97.

Tytuł:

Influence of food-derived advanced glycation end products on health

Autorzy:

Galiniak, Sabina
Bieiadecki, Marek

Powiązania:

https://bibliotekanauki.pl/articles/454957.pdf

Data publikacji:

2018

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

advanced glycation end products AGEs
CML
diabetes
glycation

Opis:

Introduction. Advanced glycation end products (AGEs) are compounds formed endogenously in the human body. Besides this source of AGEs, they also exist in food and can be generated during cooking. Enhanced endogenous generation and intake of dietary AGEs have physiological impact on human health and are associated with progression of many diseases, including diabetes and its complications. Aim. The purpose of this review is to the present the current state of knowledge about the various negative effects of advanced glycation end products on human health. Materials and methods. This study is based on analysis of literature reporting the content of AGEs in food and high or low AGEs dietary interventions in human and animal subjects. Results. Literature data present databases gathering description of AGEs determinations in various types of food. Conclusions. Excessive consumption of AGEs-rich products, especially abundant in protein and fat or cooked for a long time at high temperature, may contribute to the deterioration of human health, including development of hypertension, insulin resistance, and diabetic complications.

Źródło:

European Journal of Clinical and Experimental Medicine; 2018, 4; 330-334
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 98.

Tytuł:

Heterogeneity of change in state affect following insulin therapy initiation in type 2 diabetic patients

Autorzy:

Kroemeke, Aleksandra
Kwissa-Gajewska, Zuzanna
Gruszczyńska, Ewa

Powiązania:

https://bibliotekanauki.pl/articles/2128257.pdf

Data publikacji:

2017

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

latent class growth modeling
type 2 diabetes
affect

Opis:

The aim of the study was to explore heterogeneity of change in state affect following the introduction of insulin therapy in patients with type 2 diabetes. State affect was assessed twice among 305 patients: just before the introduction of insulin therapy and at 1-month follow-up. Latent class growth modeling showed that negative affect (NA) increased in 78% of the sample, whereas positive affect (PA) improved in only 17% of the participants. On the basis of cross-tabulation of these changes a 4-class model of emotional response to the new treatment was obtained. The largest subgroup of participants (57%) manifested “threat response”, i.e. moderate-stable PA with increase in NA. Participants in the “challenge response” subgroup (11.8%) showed increases in both NA and PA. The third class (10.2%) characterized by “no response”, had low-stable NA and moderate-stable PA. The smallest “stress response” subgroup (9.8%) showed increase in NA and high-stable PA. Gender, age and education level were significant covariates of group membership. Thus, the findings revealed heterogeneous emotional response to the new treatment, which may be of clinical relevance for improving diabetic patients’ adjustment through a more individual, person-centered approach.

Źródło:

Polish Psychological Bulletin; 2017, 3; 338-346
0079-2993

Pojawia się w:

Polish Psychological Bulletin

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 99.

Tytuł:

Zastosowanie komórek macierzystych w leczeniu cukrzycy
Stem cell treatment for diabetes

Autorzy:

Nowak, Dorota
Klakla, Katarzyna
Fatyga, Edyta
Błażelonis, Adam

Powiązania:

https://bibliotekanauki.pl/articles/1039062.pdf

Data publikacji:

2012

Wydawca:

Śląski Uniwersytet Medyczny w Katowicach

Tematy:

komórki macierzyste
cukrzyca
leczenie
stem cells
diabetes
treatment

Opis:

Immunomodulatory features, unlimited possibilities of self-renewal, multidirectional differentiation, the ability to selectively migrate to the injury site – these are the features of stem cells which allow them to be seen as a promising therapeutic tool. The study shows the division of stem cells on the basis of their ability to differentiate and origin, the source of their acquisition and the possible therapeutic effect on diabetes and its organ complications. The safety aspects as well as the limitations of the analysed methods are discussed.
Właściwości immunomodulacyjne, nieograniczone możliwości samoodnawiania, wielokierunkowe różnicowanie oraz zdolność selektywnej migracji do miejsca uszkodzeń – to cechy komórek macierzystych, pozwalające postrzegać je jako obiecujące narzędzie terapeutyczne. W pracy omówiono podział komórek macierzystych ze względu na zdolność różnicowania i pochodzenie, źródła ich pozyskiwania oraz możliwy efekt terapeutyczny w cukrzycy i jej powikłaniach narządowych. Analizowano również aspekty bezpieczeństwa oraz ograniczenia omawianej metody.

Źródło:

Annales Academiae Medicae Silesiensis; 2012, 66, 5; 71-76
1734-025X

Pojawia się w:

Annales Academiae Medicae Silesiensis

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 100.

Tytuł:

Eating habits of patients with type 2 diabetes mellitus with regard to body mass index
Nawyki żywieniowe pacjentów z cukrzycą typu 2 z uwzględnieniem wskaźnika masy ciała

Autorzy:

Janion, Karolina
Szczepańska, Elżbieta

Powiązania:

https://bibliotekanauki.pl/articles/765988.pdf

Data publikacji:

2017

Wydawca:

Śląski Uniwersytet Medyczny w Katowicach

Tematy:

BMI
diabetes mellitus
eating habits
cukrzyca
nawyki żywieniowe

Opis:

INTRODUCTION: Recent years have seen a significant increase in the incidence of diabetes mellitus, type 2 diabetes in particular, which closely correlates with the growing problem of overweight and obesity. The aim of the study was to compare eating habits among type 2 diabetic patients with varying body weight as well as to verify whether there was a relationship between dietary habits and the body mass index in these patients. MATERIAL AND METHODS: The study was conducted in diabetology outpatient clinics. A total of 353 diabetic patients participated in the study. The study consisted of two parts, i.e. authors' questionnaire and anthropometric measurements. RESULTS: The recommended number of 4–5 meals a day was declared by 48.6% of subjects with normal body weight, 50.3% of overweight and 48.4% of obese patients. Daily consumption of breakfast was confirmed by 77.1%, 73.9% and 77.8% of respondents, respectively. Daily consumption of whole-grain bread and coarse grits was mostly declared by subjects with normal body weight (62.8%), followed by overweight and obese patients (22.9% and 23%, respectively). Daily consumption of milk and fermented dairy beverages was reported by 24.3% and 15.7% of subjects with normal body weight, 22.3% and 14.7% of overweight patients as well as by 16.7% and 12% of obese patients, respectively. CONCLUSIONS: Eating habits among patients with type 2 diabetes are varied, with healthy eating habits dominating in subjects with normal body weight. A relationship was found between the patients’ BMI values and some of the eating habits as well as consumption rates of various food products.
WSTĘP: W ostatnich latach odnotowuje się znaczący wzrost zachorowalności na cukrzycę, zwłaszcza typu 2, co ściśle koreluje z narastającym problemem nadwagi i otyłości. Celem pracy było porównanie nawyków żywieniowych pacjentów z cukrzycą typu 2 o różnej masie ciała oraz odpowiedź na pytanie, czy występują zależności pomiędzy nawykami a wskaźnikiem masy ciała (BMI) badanych osób. MATERIAŁ I METODY: Badanie zostało przeprowadzone w poradniach diabetologicznych wśród 353 pacjentów z cukrzycą. Składało się z dwóch części – przeprowadzenia ankiety z wykorzystaniem autorskiego kwestionariusza oraz wykonania pomiarów antropometrycznych. WYNIKI: Spożywanie zalecanej liczby 4–5 posiłków w ciągu dnia zadeklarowało 48,6% osób z prawidłową masą ciała, 50,3% z nadwagą oraz 48,4% z otyłością. Codzienne spożywanie I śniadania potwierdziło odpowiednio 77,1%, 73,9% oraz 77,8% z nich. Codzienną konsumpcję pełnoziarnistego pieczywa i gruboziarnistych kasz najczęściej deklarowały osoby z prawidłową masą ciała (62,8%), rzadziej osoby z nadwagą i otyłością, odpowiednio 22,9% i 23% wskazań. Spożycie mleka i mlecznych napojów fermentowanych każdego dnia deklarowało odpowiednio 24,3% i 15,7% osób z prawidłową masą ciała, 22,3% i 14,7% z nadwagą oraz 16,7% i 12% z otyłością. WNIOSKI: Nawyki żywieniowe badanych pacjentów z cukrzycą typu 2 są zróżnicowane, przy czym największą liczbę prawidłowych nawyków żywieniowych zaobserwowano u osób z prawidłową masą ciała. Stwierdzono, iż występuje zależność pomiędzy BMI badanych pacjentów a niektórymi nawykami żywieniowymi i częstością spożycia poszczególnych produktów spożywczych.

Źródło:

Annales Academiae Medicae Silesiensis; 2017, 71; 363-370
1734-025X

Pojawia się w:

Annales Academiae Medicae Silesiensis

Dostawca treści:

Biblioteka Nauki

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