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Wyświetlanie 1-10 z 446
Tytuł:
Contribution of the intra- and intermolecular routes in autocatalytic zymogen activation: application to pepsinogen activation
Autorzy:
Varón, Ramón
Fuentes, Matilde
García-Moreno, Manuela
Garcìa-Sevilla, Francisco
Arias, Enrique
Valero, Edelmira
Arribas, Enrique
Powiązania:
https://bibliotekanauki.pl/articles/1041258.pdf
Data publikacji:
2006
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
intermolecular activation
intramolecular activation
autocatalysis
enzyme kinetics
proenzyme activation
Opis:
Taking as the starting point a recently suggested reaction scheme for zymogen activation involving intra- and intermolecular routes and the enzyme-zymogen complex, we carry out a complete analysis of the relative contribution of both routes in the process. This analysis suggests the definition of new dimensionless parameters allowing the elaboration, from the values of the rate constants and initial conditions, of the time course of the contribution of the two routes. The procedure mentioned above related to a concrete reaction scheme is extrapolated to any other model of autocatalytic zymogen activation involving intra- and intermolecular routes. Finally, we discuss the contribution of both of the activating routes in pepsinogen activation into pepsin using the values of the kinetic parameters given in the literature.
Źródło:
Acta Biochimica Polonica; 2006, 53, 2; 407-420
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The mechanism of azide activation of polyphenol oxidase II from tobacco.
Autorzy:
Shi, Chunhua
Liu, Qingliang
Dai, Ya
Xie, Yongshu
Xu, Xiaolong
Powiązania:
https://bibliotekanauki.pl/articles/1043711.pdf
Data publikacji:
2002
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
polyphenol oxidase (PPO)
azide activation
peroxide activation
superoxide activation
copper proteins
Opis:
So far, azide has been consistently reported to act as an inhibitor of metal enzymes, especially copper proteins. The present work shows that azide can also act as an activator of polyphenol oxidase II (PPO II) from tobacco leaves. From0 the square-wave voltammetry of native PPO II, peroxide-PPO II complex and azide-PPO II complex, the reduction of nitro blue tetrazolium by the enzymes and activation of PPO II by peroxide it follows that the binding of azide to PPO II induces the formation of CuO(2)(2-)Cu in the active site of PPO II from CuO(2)(-)Cu in native PPO II. The reason for azide acting as an activator can be attributed to azide complexing with PPO II, thus inducing the formation of CuO(2)(2-)Cu, which is the active site of the peroxide-PPO II complex in which peroxide plays the role of activator.
Źródło:
Acta Biochimica Polonica; 2002, 49, 4; 1029-1035
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Determination of the emission rate for the 14 MeV neutron generator with the use of radio-yttrium
Autorzy:
Laszynska, E.
Jednorog, S.
Ziolkowski, A.
Gierlik, M.
Rzadkiewicz, R.
Powiązania:
https://bibliotekanauki.pl/articles/146115.pdf
Data publikacji:
2015
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
14 MeV neutron generator
activation method
yttrium activation
Opis:
The neutron emission rate is a crucial parameter for most of the radiation sources that emit neutrons. In the case of large fusion devices the determination of this parameter is necessary for a proper assessment of the power release and the prediction for the neutron budget. The 14 MeV neutron generator will be used for calibration of neutron diagnostics at JET and ITER facilities. The stability of the neutron generator working parameters like emission and angular homogeneity affects the accuracy of calibration other neutron diagnostics. The aim of our experiment was to confi rm the usefulness of yttrium activation method for monitoring of the neutron generator SODERN Model: GENIE 16. The reaction rate induced by neutrons inside the yttrium sample was indirectly measured by activation of the yttrium sample, and then by means of the γ-spectrometry method. The pre-calibrated HPGe detector was used to determine the yttrium radioactivity. The emissivity of neutron generator calculated on the basis of the measured radioactivity was compared with the value resulting from its electrical settings, and both of these values were found to be consistent. This allowed for a positive verifi cation of the reaction cross section that was used to determine the reaction rate (6.45 × 10–21 reactions per second) and the neutron emission rate (1.04 × 108 n·s–1). Our study confi rms usefulness of the yttrium activation method for monitoring of the neutron generator.
Źródło:
Nukleonika; 2015, 60, 2; 319-322
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Włączenie społeczne osób z niepełnosprawnością intelektualną
Autorzy:
Kuta, Tomasz
Adamek, Dominik
Powiązania:
https://bibliotekanauki.pl/articles/2157767.pdf
Data publikacji:
2016
Wydawca:
Instytut Studiów Międzynarodowych i Edukacji Humanum
Tematy:
inclusion
mental disability
society
social activation
professional activation
Opis:
People with mental disabilities are a great group of members of our society. This article presents a development of approach to people touched with mental disablities over the years. The opportunities for their needs to be met by society were presented and discussed. The ways of their social inclusion and social and professional activation were presented as well.
Źródło:
Społeczeństwo i Edukacja. Międzynarodowe Studia Humanistyczne; 2016, 1(20); 215-223
1898-0171
Pojawia się w:
Społeczeństwo i Edukacja. Międzynarodowe Studia Humanistyczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Implementation of innovative social investments at the local level. Case study
Autorzy:
Moroń, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/583431.pdf
Data publikacji:
2018
Wydawca:
Wydawnictwo Uniwersytetu Ekonomicznego we Wrocławiu
Tematy:
social innovation
social investments
social activation
professional activation
homelessness
accompaniment method
Opis:
The article presents the results of research on the implementation of innovative social investments at the local level based on the case study Assistance from A to Z – Professional activation of homeless people from Wroclaw Circle St. Brother Albert Aid Society. The aim is to analyse the possibilities of applying innovative and investment solutions in the area of social and professional activation of people threatened by social exclusion, especially the homeless. The author uses the case study method and the method of desk research, in which the analysis of the strategy documents, source materials and acts was carried out. The analysis of the Assistance from A to Z project showed that applied in the project forms of support brought satisfactory results in the field of social and professional activation of the homeless, brought social and economic benefits and thus the project can be seen as a social investment.
Źródło:
Prace Naukowe Uniwersytetu Ekonomicznego we Wrocławiu; 2018, 510; 140-151
1899-3192
Pojawia się w:
Prace Naukowe Uniwersytetu Ekonomicznego we Wrocławiu
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Rządzenie aktywizacją – ujęcie metodologiczne
Governance of activation – methodological approach
Autorzy:
Mering, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/473800.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
rządzenie
aktywizacja
governance
activation
Opis:
Podstawowym celem artykułu jest określenie użyteczności koncepcji rządzenia (governance) dla analizy programów aktywnej polityki społecznej (APS). W opracowaniu wykazano, że governance jest szeroka perspektywą badawczą, która pozwala na wielowymiarowe badania empiryczne. Rządzenie jest właściwą kategoria do analizowania funkcjonowania podmiotów polityki społecznej odpowiedzialnych za programy aktywnej polityki społecznej. Podstawową zaletą governance jest aktualność tego podejścia, którą dobrze oddaje hasło „rządzenia bez rządu” w ramach powiązań sieciowych i z wykorzystaniem szerokie spektrum instrumentów współczesnego zarządzania.
The main objective of this paper is to discuss a general concept of governance for the analysis of active social policy programs (APS). The study shows that governance is a broad prospect research, which allows for multi-dimensional empirical studies. Governance is the right category to analyze the functioning of bodies responsible for social policy programs of an active social policy. The main advantage of governance is the relevance of this approach, which is well illustrated by the slogan “governance without government” in the network connections and using a wide range of contemporary management instruments.
Źródło:
Problemy Polityki Społecznej. Studia i Dyskusje; 2013, 22(3); 131-148
1640-1808
Pojawia się w:
Problemy Polityki Społecznej. Studia i Dyskusje
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Zatrudnienie socjalne w województwie mazowieckim
The Social Employment in the Mazovia Voivodship
Autorzy:
Kruk, Anna Monika
Powiązania:
https://bibliotekanauki.pl/articles/586367.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Ekonomiczny w Katowicach
Tematy:
Aktywizacja bezrobotnych
Aktywizacja rynku pracy
Spółdzielnie
Zatrudnienie
Employment
Labour market activation
Unemployed activation
Opis:
This article is the result of investigative experiences attribution to social employment organization by author. Text shows the general information about number of institutions, selected unemployment and demographic aspect based on Mazovia Voivodship. It is a news report of investigation on research projects: "Social employment as a chance for activity of marginalized people" and "Social-organizational difficulties in activity of social employment institutions". The research projects were sponsoring by The Maria Grzegorzewska Academy of Special Education. The type of organizations described in this article are: the social integration centers; the social integration clubs; the social cooperatives
Źródło:
Studia Ekonomiczne; 2014, 167; 139-147
2083-8611
Pojawia się w:
Studia Ekonomiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Boride Layer Growth Kinetics of AISI H13 Steel Borided with Nano-Sized Powders
Autorzy:
Karakaş, M. S.
Günen, A.
Kanca, E.
Yilmaz, E.
Powiązania:
https://bibliotekanauki.pl/articles/351842.pdf
Data publikacji:
2018
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
boriding
growth kinetics
activation energy
Opis:
Growth kinetics of boride layers in AISI H13 steel was investigated using the pack boriding method at temperatures of 1073, 1173 and 1273 K (800°C, 900°C and 1000°C) for periods of 2, 4 and 6 h with nano-sized boron (NB) and micron-sized Ekabor II powders as boriding agents. The total thickness of the boride layer (including both FeB and Fe2B) after boriding at 1273 K (1000°C) for 6 h was 103.8 μm and 96.5 μm for the NB and Ekabor II specimens, respectively. X-ray diffraction analysis of the boride layers on the surfaces borided with NB and Ekabor II revealed the presence of FeB and Fe2B phases with sawtooth morphology. The FeB/Fe2B volume ratio was higher in the specimens borided with NB. The thickness of the boride layer (FeB + Fe2B) increased with the increasing boriding temperature and time. The FeB layer in the NB specimen displayed a (002) preferred orientation.
Źródło:
Archives of Metallurgy and Materials; 2018, 63, 1; 159-165
1733-3490
Pojawia się w:
Archives of Metallurgy and Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The surface features of activated stibnite surface with copper or lead ion
Autorzy:
Cao, Q.
Huang, Y.
Zou, H.
Wen, S.
Powiązania:
https://bibliotekanauki.pl/articles/110393.pdf
Data publikacji:
2018
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
stibnite
flotation
activation
active layer
Opis:
Cu2+ and Pb2+ are widely used as activators for the flotation of stibnite. In this work, by the treatment of Cu2+ or Pb2+, the activation product and the thickness of activation layer on the stibnite surface were both investigated. Based on the flotation results, zeta potential analysis and X-ray photoelectron spectroscopy (XPS) study, it was found that Cu2+ was reduced to Cu+ at the stibnite surface and a layer of Cu2S was formed at the surface. While, a PbS layer presenting at the stibnite surface is responsible for the activation flotation of stibnite with Pb2+. Time of flight secondary ion mass spectrometry (TOF-SIMS) analysis further implies that, when stibnite was activated with 5×10-5 mol/dm3 of CuSO4 or Pb(NO3)2, the thickness of Cu2S layer on the Cu-activated surface was close to 2.7 nm, while the thickness of PbS layer was about 1.8 nm on the Pb-activated surface.
Źródło:
Physicochemical Problems of Mineral Processing; 2018, 54, 3; 763-770
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Aktywizacja i oddolna inicjatywa mieszkańców jako metody działania na rzecz rozwoju lokalnego jednostek pomocniczych gminy na przykładzie sołectw
Activation And Grassroots Initiative Of Residents As A Method Of Action For The Development Of Municipality Support On The Example Of Municipal Subdivisions
Autorzy:
Biniasz-Celka, Danuta
Powiązania:
https://bibliotekanauki.pl/articles/911509.pdf
Data publikacji:
2019-03-15
Wydawca:
Uniwersytet im. Adama Mickiewicza w Poznaniu
Tematy:
activation
grassroots initiative
resources
development
Opis:
Activation and grassroots initiative of inhabitants are components of social change affecting local development. It is here that ideas materialise through the actions of individuals. It is assumed that development always exists in an active relation to social and cultural change, involving human, financial, environmental and infrastructural resources. It includes primarily community interactions of individuals in the process of activation for the local environment. The study assumed the hypothesis that activation and grass-roots initiative have a significant impact on local development of auxiliary units. The management of local affairs is based on the assumption that inhabitants of a certain area constitute a community aware of their needs and objectives, able to manage their own affairs independently. Activation and development of the community is defined as a collective undertaking, which requires, among other things, emotional commitment and effort of residents. It is a process that follows the steps of planned operation which involves preparing the action programme, establishing the aim, and setting ways to its implementation. At the same time there must be determined a method which will allow to achieve the intended effectiveness of the undertaking. Comprehensive understanding of activation and grassroots initiative indicates the role of development planning, strategy, and the importance of citizen participation in building a better future for their own socio-cultural environment. Activation within the meaning of citizen activation is associated with the search for independence and identification with the community and place as a “little homeland.”
Źródło:
Studia Prawa Publicznego; 2019, 1, 25; 145-160
2300-3936
Pojawia się w:
Studia Prawa Publicznego
Dostawca treści:
Biblioteka Nauki
Artykuł
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