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Tytuł:
Authors’ response (April 30, 2018) to the letter to the editor concerning the paper “Histological findings and lung dust analysis as the basis for occupational disease compensation in asbestos-related lung cancer in Germany”
Autorzy:
Feder, Inke S.
Theile, Anja
Tannapfel, Andrea
Powiązania:
https://bibliotekanauki.pl/articles/2162025.pdf
Data publikacji:
2018-12-20
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
asbestos bodies
occupational disease
lung fiber burden
lung dust analysis
lung cancer
compensation
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2018, 31, 6; 849-851
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Innovations in lung cancer treatment
Autorzy:
Sieńko, Anna
Rożenek, Karolina
Nalewaj, Piotr
Bożyk, Aleksandra
Krawczyk, Paweł
Powiązania:
https://bibliotekanauki.pl/articles/1178237.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Immunotherapy
Lung cancer
Lung cancer treatment
targeted therapy
Opis:
Lung cancer is associated with one of the highest mortality rates among malignant tumors. It is the main death cause of men and women in Poland where over 15 000 men and 7 000 women die with this diagnosis annually. 1.7 million people die every year due to lung cancer in the world. Two main types of lung cancer are small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). The history of lung cancer treatment begins with surgical approach followed by addition of chemotherapy and radiotherapy, which were used either separately or in combination depending on the stage of the lung cancer. Many somatic mutations were identified and molecularly targeted therapies could have been established. One of the oldest and the best known group of molecularly targeted drugs used in lung cancer treatment are tyrosine kinase inhibitors (TKIs) of epidermal growth factor receptor (EGFR). First EGFR-TKI was gefitinib, which has been examined in clinical trials before erlotinib, afatinib, dacomitinib and osimertinib. EGFR-TKIs increased overall survival (OS) with significantly less side effects when compared to standard chemotherapy. Another group of molecularly targeted drugs are anaplastic lymphoma (ALK) kinase inhibitors such as crizotinib, alectinib and ceritinib. Another innovation which was introduced in NSCLC treatment was immunotherapy. Its effect is based on modification of immune system leading to activation of cytotoxic T lymphocytes (CTL). Currently nivolumab and pembrolizumab (anti-PD1 antibodies) as well as atezoliumab (anti-PD-L1 antibody) are being used in NSCLC patients. The discovery of innovative therapies for NSCLC patients resulted in significant extension of patients' life expectancy while minimizing the side effects of such therapy. Moreover, the quality of patients’ life was significantly improved. However, important problems still remain to be solved: overcoming the resistance in the course of molecularly targeted therapies and the lack of predictive factors that determine the effectiveness of immunotherapy.
Źródło:
World Scientific News; 2018, 93; 115-124
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Authors’ response (March 14, 2018) to the letter to the Editor concerning the paper “Histological findings and lung dust analysis as the basis for occupational disease compensation in asbestos-related lung cancer in Germany”
Autorzy:
Feder, Inke S.
Theile, Anja
Tannapfel, Andrea
Powiązania:
https://bibliotekanauki.pl/articles/2162041.pdf
Data publikacji:
2018-12-20
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
lung cancer
occupational disease
compensation
asbestos bodies
lung asbestos fiber burden
lung dust analysis
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2018, 31, 6; 841-843
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pulmonary lymphangitic carcinomatosis in the course of gastric cancer - Case report
Autorzy:
Witczak, A.
Prystupa, A.
Zamecka, M.O.
Bilan, A.
Krupski, W.
Mosiewicz, J.
Powiązania:
https://bibliotekanauki.pl/articles/3002.pdf
Data publikacji:
2014
Wydawca:
Instytut Medycyny Wsi
Tematy:
pulmonary lymphangitic carcinomatosis
gastric cancer
interstitial lung disease
lung
Opis:
Pulmonary lymphangitic carcinomatosis is a special type of diffuse metastasis of carcinoma in the lymphatic vessels of the lungs. Lymphangitic carcinomatosis is commonly observed in malignancies of the breast, lung, pancreas, colon and cervix as a strong marker for poor prognosis. Presenting with common respiratory symptoms, it may be easily misdiagnosed as other pulmonary interstitial diseases. Pulmonary lymphangitic carcinomatosis is a rare manifestation of metastatic gastric cancer. The presented case describes a patient with pulmonary lymphangitic carcinomatosis in the course of stomach cancer. The primary diagnosis was established based on the exclusion of other interstitial lung diseases, with the use of imaging techniques as well as biochemical, microbiological and cytological findings. The patient’s general condition was very severe, rendering him bedridden and therefore not eligible for any treatment, including chemotherapy. He died suddenly before final verification of the diagnosis. Pulmonary lymphangitic carcinomatosis should be suspected in patients with advanced gastric cancer, presenting with symptoms and signs of respiratory disease. Imaging techniques are mostly helpful to establish the diagnosis.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2014, 08, 2
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Histological findings and lung dust analysis as the basis for occupational disease compensation in asbestos-related lung cancer in Germany
Autorzy:
Feder, Inke S.
Theile, Anja
Tannapfel, Andrea
Powiązania:
https://bibliotekanauki.pl/articles/2159908.pdf
Data publikacji:
2017-12-21
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
occupational disease
lung asbestos fiber burden
asbestos bodies
lung cancer
lung dust analysis
compensation
Opis:
Objectives This study has researched the significance of histologically raised findings and lung dust analyses in the context of claiming the recognition of and thus compensation for an asbestos-associated occupational disease. Material and Methods For this approach, all findings from the German Mesothelioma Register in 2015 that included lung dust analyses were evaluated and were compared with information on asbestos fiber exposure at work based on fiber years, and with the results of radiological findings. Results For 68 insured persons, recognition of an asbestos-induced lung disease according to Section 4104 of the German Ordinance on Occupational Diseases (Berufskrankheitenverordnung – BKV) could be recommended solely on the basis of the histological examinations of lung tissues and complementary lung dust analyses. Neither did the calculation of the cumulative asbestos dust exposure at work yield 25 fiber years, nor could bridge findings (e.g., plaques) be identified. In addition, the autopsies of 12 patients revealed plaques that had not been diagnosed during radiological examinations. These results show that – irrespective of the prescribed working techniques and radiological diagnosis – pathological/anatomical and histological diagnostics are often the only way for the insureds to demonstrate the causal connection between asbestos and their disease. Even after long intervals of up to 40 years post last exposure, the asbestos fibers would still be easily detectable in the lung tissues evaluated. Conclusions Whenever suitable tissue is available, it should be examined for mild asbestosis with the aid of a lung dust analysis. Otherwise there is a risk that an occupational disease is wrongfully rejected. In the context of health insurance, the lung dust analysis and the resulting proof of the presence of asbestosis often constitute one option of providing evidence of an occupational disease. Int J Occup Med Environ Health 2018;31(3):293–305
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2018, 31, 3; 293-305
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Is a linear probe helpful in diagnosing diseases of pulmonary interstitial spaces?
Czy głowica liniowa jest pomocna w diagnostyce chorób zajmujących przestrzeń śródmiąższową płuc?
Autorzy:
Buda, Natalia
Kosiak, Wojciech
Powiązania:
https://bibliotekanauki.pl/articles/1033448.pdf
Data publikacji:
2017
Wydawca:
Medical Communications
Tematy:
interstitial lung disease
Opis:
In a lung ultrasound examination, interstitial lung lesions are visible as numerous B-line artifacts, and are best recorded with the use of a convex probe. Interstitial lung lesions may result from many conditions, including cardiogenic pulmonary oedema, non-cardiogenic pulmonary oedema, or interstitial lung disease. Hence difficulties in the differential diagnostics of the above clinical conditions. This article presents cases of patients suffering from interstitial lung lesions discovered in the course of lung ultrasound examination. The patients were examined with a 3.5–5.0 MHz convex probe and a 7.0–11.0 MHz linear probe. Ultrasound images have been analysed, and differences in the imaging with both probes in patients with interstitial lung lesions have been detailed. The use of a linear probe in patients with interstitial lung lesions (discovered with a convex or a micro-convex probe) provides additional information on the source of the origin of the lesions.
Zmiany śródmiąższowe płuc w badaniu ultrasonograficznym prezentują się jako liczne artefakty linii B, rejestrowane najlepiej przy pomocy sondy konweksowej. Przyczyn zmian śródmiąższowych płuc może być wiele: kardiogenny obrzęk płuc, niekardiogenny obrzęk płuc oraz zmiany w przebiegu śródmiąższowych chorób płuc. Powoduje to trudności w diagnostyce różnicowej powyższych stanów klinicznych. W artykule przedstawiono serię przypadków pacjentów, u których w badaniu ultrasonograficznym płuc stwierdzono zmiany śródmiąższowe płuc. Badania wykonano przy pomocy sondy konweksowej (3,5–5,0 MHz) oraz liniowej (7,0–11,0 MHz). Dokonano analizy obrazów ultrasonograficznych oraz wskazano różnice w obrazowaniu obiema głowicami w grupie pacjentów ze zmianami śródmiąższowymi w płucach. Zastosowanie sondy liniowej u pacjentów ze stwierdzonymi (przy pomocy sondy konweksowej lub mikrokonweksowej) zmianami śródmiąższowymi płuc wnosi nowe informacje na temat źródła ich pochodzenia. Artykuł w wersji polskojęzycznej jest dostępny na stronie http://jultrason.pl/index.php/wydawnictwa/volume-17-no-69
Źródło:
Journal of Ultrasonography; 2017, 17, 69; 136-141
2451-070X
Pojawia się w:
Journal of Ultrasonography
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hyponatremia secondary to the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) during the course of lung cancer. A case report
Autorzy:
Radzka, Agnieszka
Fałkowska, Urszula
Sławiński, Aleksander
Ryczkowski, Aleksander
Obel, Ewa
Lewicki, Marcin
Powiązania:
https://bibliotekanauki.pl/articles/454668.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
hyponatremia
SIADH
lung cancer
Opis:
Introduction. Hyponatremia is a frequently observed electrolyte disorder among patients with cancer. In 1957, Schwartz et al. reported the first case of a patient with hyponatremia due to SIADH, secondary to lung cancer. From that moment on, there has been data published that indicates patients with SIADH are less responsive to chemotherapy, have greater predisposition to central nervous system metastases and are often characterized by an advanced stage of cancer during time of diagnosis. Hyponatremia has many possible causes, and the differential diagnosis can pose a challenge. Aim. The aim of the study was to consider the occurrence of secondary hyponatremia in the course of cancer and the significance of this disorder in the prognosis of the disease. Methods. An analysis of the clinical history of the patient and a review of available literature. Results. A 66-year old patient with hyponatremia was admitted to the Department of Endocrinology, and lung cancer was determined as the cause of the aforementioned electrolyte disorder. Conclusion. SIADH secondary to cancers should be included in a differential diagnosis of every case of hyponatremia of undetermined etiology.
Źródło:
European Journal of Clinical and Experimental Medicine; 2018, 2; 163-167
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pulmonary actinomycosis - the great imitator
Autorzy:
Grzywa-Celińska, A.
Emeryk-Maksymiuk, J.
Szmigin-Millanowska, K.
Czekajska-Cherhab, E.
Milanowski, J.
Powiązania:
https://bibliotekanauki.pl/articles/2081602.pdf
Data publikacji:
2018
Wydawca:
Instytut Medycyny Wsi
Tematy:
actinomycosis
imitator
lung cancer
Opis:
Pulmonary localisation represents only 15% of all cases of actinomycosis. The clinical symptoms and radiological changes of this disease are non-specific and sometimes it can be misdiagnosed, usually as tuberculosis, lung cancer or lung abscess. In the reported case, what might look like the lung cancer, finally turned out to be actinomycosis. The interesting case is presented of lung actinomycosis in a 77-year-old farmer, admitted to the Department of Pneumonology, Oncology and Allegology in Lublin due to a massive haemoptysis. CT scan of the chest showed, apart from other changes, the spicular consolidation in the right lung which aroused oncology vigilance. The diagnostic path, which was a real medical challenge, led to the diagnosis of actinomycosis. The process of diagnosis and consequent treatment, which led to the complete regression of clinical and radiological changes, is presented.
Źródło:
Annals of Agricultural and Environmental Medicine; 2018, 25, 2; 211-212
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Thiram - toxic inhalational lung injury
Autorzy:
Siwiec, J.
Siek, E.
Grzywa-Celińska, A.
Mackiewicz, B.
Czekajska-Chehab, E.
Powiązania:
https://bibliotekanauki.pl/articles/2085136.pdf
Data publikacji:
2019
Wydawca:
Instytut Medycyny Wsi
Tematy:
thiram
lung injury
inhalation
Opis:
Introduction. Thiram, a fungicides, is widely used on seeds and as foliar agent on turf, vegetables and fruit. It is also used in the rubber industry as a vulcanization accelerator. When absorbed through the respiratory system, it is rapidly metabolised to dimethylthiocarbamate and carbon disulphide, causing noxious effects. A brief review is presented of the literature, centering on the interesting case of a 45-year-old woman admitted to the hospital suffering from acute respiratory failure. Results. Computer tomography in angiographic option (angio-CT) showed an extensive, irregular area of ground glass in both upper lobes and apical segments of the lower lobes of the lungs. A significant enlargement of both atria was also described. There was no improvement after cardiac treatment and patient was transferred to the pulmonary department where she was succesfully treated with systemic glucocortycosteroids. The patient remains under the supervision of the pulmonary out-patient department.
Źródło:
Annals of Agricultural and Environmental Medicine; 2019, 26, 4; 672-673
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Combined analysis of onco-epidemiological studies of the relationship between lung cancer and indoor radon exposure
Autorzy:
Yarmoshenko, Ilia V.
Malinovsky, Georgy P.
Powiązania:
https://bibliotekanauki.pl/articles/146354.pdf
Data publikacji:
2020
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
lung cancer
radon
relative risk
Opis:
Objectives: Recent results of epidemiological and medical statistics studies of lung cancer and indoor radon in different regions of the world make a relevant new combined analysis of residential exposure health effects. In particular, new data were obtained by means of a meta-analysis of case-control studies as well as taking into account a confounding effect of human papillomavirus infection in studies of geographically aggregated data. Materials and methods: Two sources of epidemiological data are considered: (1) studies of ecological design and (2) case-control studies. Ecological studies included the analysis performed for the USA counties and Russian oblasts with adjusting for the main confounders. Data on the case-control studies were gained from the meta-analysis of 31 individual studies with a weighting of obtained odds ratios according to the quality of radon exposure reconstruction and size of the reference group. Estimations of lung cancer excess relative risk (ERR) associated with indoor radon exposure are combined. Results: Two types of epidemiological study design provided generally consistent EER estimations. The combined value of ERR due to radon exposure is 0.14 (90% CI: 0.10–0.18) per 100 Bq/m3 . Conclusion: Available geographically aggregated data in regions of Russia and the United States and the meta-analysis of case-control studies conducted in a large number of countries confirm the association of lung cancer with indoor radon exposure.
Źródło:
Nukleonika; 2020, 65, 2; 83-88
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Oxidative stress assessment in lung of lead-exposed rats
Ocena stresu oksydacyjnego w płucach szczurów narażonych na ołów
Autorzy:
Machoń-Grecka, Anna
Kaletka, Zbigniew
Pryzwan, Tomasz
Szczęsny, Patrycja
Maciejczyk, Maciej
Kasperczyk, Aleksandra
Dobrakowski, Michał
Powiązania:
https://bibliotekanauki.pl/articles/1035320.pdf
Data publikacji:
2018
Wydawca:
Instytut Medycyny Wsi
Tematy:
"lead poisoning"
"lung"
"oxidative stress"
Opis:
Objective. Little is known about lead toxic effects on lung tissue. Therefore, the present study was undertaken to estimate the values of selected parameters related to oxidative stress in the lung of rats exposed to lead acetate. Material and methods. Twenty male Wistar rats were randomly divided into two groups: control (n=10) and lead-treated (n=10). The lead-treated group was fed with regular rat chow and distilled water supplemented with lead acetate (1200 ppm) for 7 days. In lung homogenates, the level of malondialdehyde (MDA) and the activities of superoxide dismutase (SOD, CuZn-SOD, Mn-SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), and glutathione-S-transferase (GST) were determined. Results. The activity of catalase was significantly higher in the lung of lead-treated rats than in controls by 98%. Similarly, the activities of GPx and GR were higher by 57% and 45%, respectively. The level of MDA was also higher in lead-exposed rats than in the control group by 52%. The remaining parameters did not differ between the studied groups. Conclusions. Lead exposure stimulates antioxidant defense mechanisms in rat lung; however, these mechanisms are insufficient to prevent lead-induced oxidative stress development
Wstęp. Toksyczny wpływ ołowiu na tkankę płucną jest słabo poznany. W związku z tym, prezentowany eksperyment miał na celu ocenę zmian w wybranych parametrach związanych ze stresem oksydacyjnym w tkance płucnej u szczurów narażonych na octan ołowiu. Materiał i metody. Dwadzieścia szczurów szczepu Wistar, podzielono na dwie grupy: kontrolną (n=10) i badaną z podawanym ołowiem (n=10). Szczury z grupy badanej były regularnie karmione granulatem dla szczurów i pojone wodą destylowaną z octanem ołowiu (1200 ppm) przez 7 dni. W homogenatach z tanki płucnej oznaczany był poziom malonylodialdehydu (MDA) i aktywność dysmutazy ponadtlenkowej (SOD, CuZn-SOD, Mn-SOD), katalazy (CAT), peroksydazy glutationowej (GPx), reduktazy glutationowej (GR), oraz transferazy glutationowej (GST). Wyniki. Aktywność katalazy była o 98% wyższa w grupie badanej aniżeli w grupie kontrolnej. Podobnie, aktywności GPx i GR były wyższe odpowiednio o 57% i 45%. Poziom MDA był również wyższy w grupie badanej, o 52% w porównaniu do grupy kontrolnej. Pozostałe parametry nie różniły się pomiędzy grupami. Wnioski. Ekspozycja na ołów stymuluje mechanizmy obrony antyoksydacyjnej, jednakże mechanizmy te są niewystarczające by zapobiec stresowi oksydacyjnemu wywołanemu działaniem ołowiu.
Źródło:
Medycyna Środowiskowa - Environmental Medicine; 2018, 21, 1; 21-24
1505-7054
2084-6312
Pojawia się w:
Medycyna Środowiskowa - Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The relationship between chest pain and level of perioperative anxiety in patients with lung cancer
Autorzy:
Malinowska, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/1392739.pdf
Data publikacji:
2018
Wydawca:
Index Copernicus International
Tematy:
perioperative anxiety
pain
lung cancer
Opis:
Introduction: Chest pain is one of the symptoms of lung cancer. Chest pain disrupts patient’s functioning in somatic and psychic area. Purpose: Whether the existence of chest pain affects the level of perioperative anxiety in lung cancer patients. Is there a relationship between everyday functioning due to the chest pain and the level of perioperative anxiety? Is there a relation between anxiety associated with pain and gender? What is the cause of anxiety in this group of the patiens? Methodology: The study was conducted among 150 patients with lung cancer before the scheduled surgery. Data was collected with the use of questionnaire assessment of perioperative anxiety level in patients with lung cancer. Results: The chest pain before the surgery was confirmed by 63 (42%) patients, in case of 87 (58%) patients it was not identified. Chest pain was in case of 48% women and 36% men. 50 (33,3%) research participants who experienced chest pain and 35 patients (23,3%) without this symptom declared experiencing perioperative anxiety. In patients with lung cancer, the correlation: between chest pain and perioperative anxiety was (Z = -4.67; p< .001); between the difficult daily functioning of pain and perioperative anxiety was (Z = -4.72; p< .001); between gender and perioperative anxiety associated with pain was (Z = -3.24; p = 001). Patients afraid of: pain (37,3%), breathing problems (24,0%), physical disability (16,0%), eating problems (12,0%) sleep disorders (9,3%), nothing (1,3%). Conclusions: Patients with chest pain exhibited significantly higher of perioperative anxiety levels than non-symptomatic patients, as well as higher anxiety levels due to deteriorated daily functioning caused by the disorder. Women had a higher level of anxiety associated with pain than men before the surgery. Patients with lung cancer were most afraid of pain in the perioperative period.
Źródło:
Polish Journal of Surgery; 2018, 90, 2; 23-27
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Minimization of Ventilator-Induced Lung Injury in ARDS Patients – Part I: Complex Model of Mechanically Ventilated ARDS Lungs
Autorzy:
Glapiński, J.
Jabłoński, I.
Powiązania:
https://bibliotekanauki.pl/articles/221252.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
lung alveolar surfactant
respiratory mechanics
mathematical modelling
medical decision support
lung protective ventilation
Opis:
A complex model of mechanically ventilated ARDS lungs is proposed in the paper. This analogue is based on a combination of four components that describe breathing mechanics: morphology, mechanical properties of surfactant, tissue and chest wall characteristics. Physical-mathematical formulas attained from experimental data have been translated into their electrical equivalents and implemented in MultiSim software. To examine the adequacy of the forward model to the properties and behaviour of mechanically ventilated lungs in patients with ARDS symptoms, several computer simulations have been performed and reported in the paper. Inhomogeneous characteristics observed in the physical properties of ARDS lungs were mapped in a multi-lobe model and the measured outputs were compared with the data from physiological reports. In this way clinicians and scientists can obtain the knowledge on the moment of airway zone reopening/closure expressed as a function of pressure, volume or even time. In the paper, these trends were assessed for inhomogeneous distributions (proper for ARDS) of surfactant properties and airway geometry in consecutive lung lobes. The proposed model enables monitoring of temporal alveolar dynamics in successive lobes as well as those occurring at a higher level of lung structure organization, i.e. in a point P0 which can be used for collection of respiratory data during indirect management of recruitment/de-recruitment processes in ARDS lungs. The complex model and synthetic data generated for various parametrization scenarios make possible prospective studies on designing an indirect mode of alveolar zone management, i.e. with a minimized risk of repeated alveolar recruitment/de-recruitment and mechanical overstraining of lung tissues.
Źródło:
Metrology and Measurement Systems; 2017, 24, 4; 685-699
0860-8229
Pojawia się w:
Metrology and Measurement Systems
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Not only cigarettes - other culprits of lung cancer
Autorzy:
Grzywa-Celińska, A.
Drogoń, I.
Emeryk-Maksymiuk, J.
Chmielewska, I.
Milanowski, J.
Powiązania:
https://bibliotekanauki.pl/articles/2085178.pdf
Data publikacji:
2019
Wydawca:
Instytut Medycyny Wsi
Tematy:
lung cancer
cigarettes
e-cigarettes
Opis:
Introduction. Before cigarettes became popular, lung cancer was an extremely rare disease, but currently it is the most common cause worldwide of cancer death in both genders. Therefore, it constitutes a huge epidemiological, diagnostic and socio-economic challenge around the world. In Poland, lung cancer is the second most common carcinoma in both men and women, and it is also the most prevailing cause of carcinous death. Undoubtedly, although smoking classical cigarettes is the strongest risk factor of developing the cancer, unfortunately it is not the only one. Objective. The aim of this study was to present smoking-related factors, e.g. cigars, pipes, e-cigarettes or marijuana smoking, etiologically related to lung cancer incidence.
Źródło:
Annals of Agricultural and Environmental Medicine; 2019, 26, 4; 661-664
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Rehabilitation after anatomical resection of lung parenchyma with persistent air leakage
Rehabilitacja po anatomicznej resekcji miąższu płuca z utrzymującym się przeciekiem powietrza
Autorzy:
Janczura, Mirosław
Powiązania:
https://bibliotekanauki.pl/articles/1790776.pdf
Data publikacji:
2020-11-10
Wydawca:
Akademia Wychowania Fizycznego im. Bronisława Czecha w Krakowie
Tematy:
lung cancer
rehabilitation
resection of the lung parenchyma
rak płuca
rehabilitacja
resekcja miąższu płuca
Opis:
Anatomical resection of the lung parenchyma is the treatment of choice at an early stage of lung cancer. The inevitable result of these operations is the loss of the respiratory surface causing varying degrees of respiratory dysfunction, depending on the extent of the procedure and the operated side. Therefore, from the first hours after the operation, patients should undergo comprehensive rehabilitation, which is fundamental to minimize the risk of complications and improve respiratory function. Due to the popularization of the concept of enhanced recovery after surgery (ERAS), the importance of effective rehabilitation is increasing. One of the more common complications after anatomical resection of the lung parenchyma is persistent air leakage. There are no guidelines in the literature regarding rehabilitation in this group of patients. This paper describes the physiotherapy of patients after resection of the lung parenchyma complicated by persistent air leakage.
Anatomiczna resekcja miąższu płuca jest leczeniem z wyboru we wczesnym stadium zaawansowania raka płuca. Nieuniknionym skutkiem tych operacji jest ubytek powierzchni wymiany gazowej powodujący różnego stopnia, w zależności od rozległości zabiegu oraz operowanej strony, zaburzenie czynności oddechowej. Dlatego od pierwszych godzin po operacji pacjenci powinni być poddawani kompleksowej rehabilitacji, która ma podstawowe znaczenie dla minimalizacji ryzyka powikłań oraz poprawy funkcji oddechowej. Ze względu na upowszechnianie się koncepcji kompleksowej opieki okołooperacyjnej (ang. Enhanced recovery after surgery – ERAS), znaczenie skutecznego postępowania rehabilitacyjnego jest coraz większe. Jednym z częstszych powikłań po anatomicznej resekcji miąższu płuca jest utrzymujący się po zabiegu przeciek powietrza. W piśmiennictwie brak jest wytycznych dotyczących postępowania rehabilitacyjnego w tej grupie pacjentów. W niniejszej pracy opisano fizjoterapię pacjentów po zabiegu resekcji miąższu płuca powikłanym utrzymującym się przeciekiem powietrza.
Źródło:
Medical Rehabilitation; 2020, 24(3); 35-37
1427-9622
1896-3250
Pojawia się w:
Medical Rehabilitation
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Lung cancer mortality and radon exposure in Russia
Autorzy:
Yarmoshenko, I. V.
Malinovsky, G. P.
Powiązania:
https://bibliotekanauki.pl/articles/146532.pdf
Data publikacji:
2016
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
lung cancer
radon
relative risk
smoking
Opis:
The association between the lung cancer and indoor radon exposure in Russian population was investigated. The average indoor radon concentration for each region was estimated using the annual reports issued by the Saint-Petersburg Ramzaev Research Institute of Radiation Hygiene for the period 2008–2013. The average standardized lung cancer mortalities among males and females were estimated using the reports of the Moscow Hertzen Cancer Research Institute for the period 2008–2012. The relative risk (RR) was estimated as a ratio between the average mortality within seven exposure intervals and background mortality. The slope factors of linear dependence between the indoor radon exposure and lung cancer RR are 0.026 (–0.11÷0.17) and 0.83 (0.52–1.12) per radon concentration 100 Bq/m3 for males and females, respectively (with 90% confidence interval). The obtained results can be explained by the confounding effect of tobacco smoking. Significant excess risk of lung cancer in female population can be associated with radon exposure and low prevalence of smoking.
Źródło:
Nukleonika; 2016, 61, 3; 263-268
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The influence of saturated fatty acids on human lung epithelial cells
Autorzy:
Reczyńska, K.
Pamuła, E.
Chrzanowski, W.
Powiązania:
https://bibliotekanauki.pl/articles/286111.pdf
Data publikacji:
2017
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
epithelial cells
fatty acid
human lung
Źródło:
Engineering of Biomaterials; 2017, 20, no. 143 spec. iss.; 55
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The acceptance of illness in lung cancer patients before and after surgical treatment
Autorzy:
Nowicki, Andrzej
Graczyk, Paulina
Lemanowicz, Marzena
Powiązania:
https://bibliotekanauki.pl/articles/1392947.pdf
Data publikacji:
2017
Wydawca:
Index Copernicus International
Tematy:
lung cancer
surgery
acceptance of illness
Opis:
Summary: Lung cancer is the most common malignant tumor in the world, as well as one of the cancers with the most fatal prognosis. The acceptance of the disease is the most important element of the adaptive process. The better the illness acceptance, the lower the stress level and the higher the self-esteem, which facilitates the adaptation to the health status. Aim: The aim of this study was to assess the acceptance of the disease in patients before and after lung cancer surgery. Materials and methods: The study was conducted in 2016 at the Center of Oncology in Bydgoszcz and the Kuyavian and Pomeranian Pulmonology Center in Bydgoszcz. The study involved 87 patients who were assessed both before and after lung cancer surgery. The original questionnaire, as well as the Acceptance of Illness Scale, were used. Results: Men accounted for 75% of the probands, 65% of the study population were 50-69 years old. The highest number of patients – 25 (28.7%) had a 5-pack-year history, and the lowest amount of patients – 8 (9.2%) had a 2.5-pack-year history. The level of acceptance of illness before and after surgery differed in 58 persons. In 29, the level of acceptance remained the same, in 45, the level of acceptance decreased, and in 13 – it increased. Before surgery, the mean acceptance of illness score was 26.2 points, and after surgery – 20.89 points. The patients both after and before surgery had acceptance of illness scores regardless of their gender, age, education, place of residence or occupational activity. Conclusions: In more than a half of the patients, the acceptance of illness decreases after surgery and is at an average level. Male patients, patients aged 50-69 years, with primary, middle or vocational education, employed persons show a significantly worse illness acceptance, regardless of their place of residence, and occupational activity do not influence the acceptance of the disease.
Źródło:
Polish Journal of Surgery; 2017, 89, 4; 11-15
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of Ageratina adenophora on hepatic and pulmonic pathological lesions in horses
Autorzy:
Gu, X.L.
Dai, F.Y.
Xiao, X.
Li, G.Z.
Zhang, L.M.
Qu, W.J.
Powiązania:
https://bibliotekanauki.pl/articles/2087129.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Ageratina adenophora
liver
lung
horse
toxicity
Źródło:
Polish Journal of Veterinary Sciences; 2021, 24, 4; 611-613
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Methotrexate binding causes structural and functional changes in lung cystatin
Autorzy:
Khan, Mohd
Priyadarshini, Medha
Sumbul, Sadia
Bano, Bilqees
Powiązania:
https://bibliotekanauki.pl/articles/1040310.pdf
Data publikacji:
2010
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
FTIR
goat lung cystatin
methotrexate
emphysema
Opis:
Regulation of cysteine proteinases and their inhibitors is of utmost importance in diseases like lung cancer, chronic inflammatory conditions such as asthma, emphysema, and idiopathic pulmonary fibrosis. Protease-antiprotease imbalance accelerates disease progression. In the present study, the effect of antineoplastic and antirheumatic drug methotrexate (MTX) on lung cystatin (a cysteine protease inhibitor) was studied to explore drug induced changes in functional and structural integrity of the protein. The basic binding interaction was studied by UV-absorption, FT-IR and fluorescence spectroscopy. The quenching of protein fluorescence confirmed the binding of MTX with goat lung cystatin (GLC-I). Stern-Volmer analysis of MTX-GLC-I system at different temperatures indicates the presence of static component in the quenching mechanism. The thermodynamic parameters ΔH0 and ΔS0 were -3.8 kJ/mol and 94.97 J•mol-1•K-1, respectively, indicating that both hydrogen bonds and hydrophobic interactions played a major role in the binding of MTX to GLC-I. Methotrexate (7 µM) caused complete inactivation of lung cystatin after 6 hours. The results of FT-IR spectroscopy reflect perturbation of the goat lung cystatin on interaction with MTX. Methotrexate induced loss of function change in the inhibitor could provide a rationale for the off target tissue injury caused by the drug and for the design of agents against such an injury.
Źródło:
Acta Biochimica Polonica; 2010, 57, 4; 499-503
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Characteristics of a new respiratory syndrome associated with the use of a humidifier disinfectant: humidifier disinfectant-related respiratory syndrome (HDRS)
Autorzy:
Leem, Jong Han
Joh, Joon-Sung
Hong, Young-Seoub
Kim, Jungwon
Park, Soyoung
Lim, Soyeoun
Kim, Yangho
Powiązania:
https://bibliotekanauki.pl/articles/2116504.pdf
Data publikacji:
2020-10-20
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
pneumonitis
respiratory
lung
disinfection
injuries
humidifier
Opis:
ObjectivesThe purpose of this study was to characterize a new respiratory syndrome associated with exposure to a humidifier disinfectant (HD) in South Korea that is distinct from the well-known HD-related lung injury (HDLI). The authors identified this condition in 24 study subjects who were family members of patients with definite or probable HDLI (referred to as index cases), and were exposed to HD in the same room as the index cases.Material and MethodsThe authors reviewed medical records of 236 family members in 110 families who were exposed to HD in the same rooms and residences as the index cases.ResultsThey identified 24 family members who were exposed to HD in the same rooms and residences as the index cases, and who developed respiratory disorders that were distinct from HDLI. The clinical signs and symptoms of these individuals were in the upper respiratory tract, such as allergic rhinitis and croup, or in the lower respiratory tract, such as bronchitis and pneumonia. The diffusing capacity of the lung fordetermicarbon monoxide was reduced in 9 of 12 children (data not available for 1 child), and in 4 of 5 adults (data not available for 6 adults). The percent forced vital capacity and forced expiratory volume in one second/forced vital capacity ratios were within the normal ranges in most patients. The computed tomography findings, which mostly indicated non-specific inflammation, were inconsistent with the radiological diagnostic criteria for HDLI, but were abnormal in 8 of 11 adults, and in 2 of 13 children.ConclusionsThe authors propose a new condition, i.e., HD-related respiratory syndrome (HDRS), which is characterized by mild to moderate or atypical respiratory symptoms and signs, and is related to HD exposure, but is distinct from HDLI. The recognition of HDRS may provide a basis for understanding the natural history of HD-related respiratory problems, and for capturing the whole spectrum of HD-related clinical manifestations in the respiratory tract.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2020, 33, 6; 829-839
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Surgeon’s viewpoint on lung transplantatio in cystic fibrosis patients – preliminary report
Punkt widzenia chirurga na przeszczepianie płuc u chorych z mukowiscydozą – doniesienie wstępne
Autorzy:
Kubisa, Bartosz
Piotrowska, Maria
Milczewska, Justyna
Bielewicz, Michał
Kochanowski, Leszek
Pieróg, Jarosław
Kozak, Anna
Czarnecka, Michalina
Wójcik, Norbert
Wasilewski, Piotr
Feledyk, Grzegorz
Kubisa, Anna
Brykczyński, Mirosław
Sielicki, Piotr
Grodzki, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1032984.pdf
Data publikacji:
2015
Wydawca:
Wydawnictwo ALUNA
Tematy:
cystic fibrosis
lung transplantation
qualification
respiratory insufficiency
Opis:
Introduction: The surgeon’s viewpoint on a patient with cystic fibrosis differs from that of a pediatrician or internist. The problems a cystic fibrosis specialist encounters are different from those faced by the surgeon who takes over the patient in a very advanced, often terminal stage of the disease. Hence, the main problem for the surgeon is the decision concerning the surgery (lung transplantation, pneumonectomy, lobectomy). It is, therefore, important to lay down fundamental and appropriate rules concerning the indications and contraindications for lung transplantation, especially in patients with cystic fibrosis. Aim: The aim of this study was to analyze the methods of qualifying and preparing patients for surgery, as well as carrying out the procedure of transplantation and postoperative short and long-term care. Material and methods: The investigation was carried out on 16 patients with cystic fibrosis. Three were operated on and 10 were on the waiting list for transplantation. Two patients on the waiting list died, one patient was disqualified from transplantation. During qualification for lung transplantation, strict indications, contraindications and other factors (such as blood type, patient’s height, coexisting complications) were taken under consideration. Results: All the 3 patients after lung transplantation are alive and under our constant surveillance. Ten patients await transplantation, though four of them are suspended due to hepatitis C infection. Two patients on the waiting list died: one from respiratory insufficiency and the other in the course of bridgeto-transplant veno-venous extracorporeal membrane oxygenation due to hepatic failure. One patient has been disqualified because of cachexia. Conclusions: Since lung transplantation is the final treatment of the end-stage pulmonary insufficiency in cystic fibrosis patients, the number of such procedures in cystic fibrosis is still too low in Poland. The fast development of these procedures is highly needed. It is necessary to develop better cooperation between different disciplines and specialists, especially between pediatricians and surgeons. The correct choice of the suitable moment for lung transplantation is crucial for the success of the procedure.
Wstęp: Punt widzenia chirurga odnośnie leczenia pacjenta z mukowiscydozą różni się od spojrzenia pediatry czy internisty. Duży jest bagaż zadań lekarza specjalisty w zakresie leczenia chorego z mukowiscydozą w różnych okresach choroby, a inny chirurga, który przejmuje go w bardzo zaawansowanym, a nierzadko w terminalnym stadium. Stąd dla chirurga głównym problemem jest podjęcie decyzji odnośnie leczenia operacyjnego (transplantacja płuc, pneumonektomia, lobektomia). Dlatego tak ważne jest sformułowanie podstawowych i właściwych zasad dotyczących wskazań i przeciwwskazań do transplantacji płuc zwłaszcza w odniesieniu do pacjentów z mukowiscydozą. Cel: Celem pracy była analiza metod kwalifikacji i przygotowania, a także przeprowadzenia transplantacji oraz pooperacyjnej opieki krótko- i długoterminowej. Materiał i metody: W niniejszej pracy przedstawiamy 3 przypadki pacjentów z mukowiscydozą po zabiegu transplantacji płuc oraz 10 kandydatów, którzy w chwili obecnej są potencjalnymi biorcami narządu i oczekują na jej przeprowadzenie. Dwóch pacjentów nie doczekało przeszczepienia, jedna pacjentka została zdyskwalifikowana z zabiegu. W toku kwalifikacji do transplantacji płuc omawiane są istniejące wskazania, przeciwwskazania i szereg innych czynników (takich jak grupa krwi, wysokość ciała pacjenta, istniejące powikłania choroby podstawowej, choroby współistniejące). Wyniki: Wszyscy (troje) pacjenci po przeprowadzonej transplantacji żyją i są pod stałą kontrolą naszego ośrodka. Z dziesięciu kandydatów oczekujących na przeszczepienie, czterech jest zawieszonych na liście oczekujących z powodu infekcji (wirusowe zapalenie wątroby typu C). Dwóch pacjentów nie doczekało przeszczepienia: pierwszy zmarł z powodu niewydolności oddechowej, adrugi kwalifikowany do przeszczepienia płuc iwątroby pozostający na pozaustrojowym natlenianiu membranowym żylno-żylnym, zmarł wskutek niewydolności wątroby. Jedna pacjentka została zdyskwalifikowana z zabiegu z powodu skrajnego niedoboru masy ciała. Wnioski: Biorąc pod uwagę, że transplantacja płuc jest ostatecznym leczeniem schyłkowej niewydolności oddechowej w mukowiscydozie. Liczba wykonywanych w Polsce przeszczepień płuc u chorych z mukowiscydozą jest ciągle za mała, o czym świadczy los oczekujących pacjentów. Konieczny jest więc szybki rozwój placówek zajmujących się przeszczepieniami płuc u tych chorych. Wybór odpowiedniego momentu przeprowadzenia transplantacji płuc, ma zasadnicze znaczenie dla powodzenia procedury.
Źródło:
Developmental Period Medicine; 2015, 1; 120-126
1428-345X
Pojawia się w:
Developmental Period Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cadaver as a didactic tool for auscultating lung sounds
Ludzkie zwłoki jako narzędzie dydaktyczne w osłuchiwaniu płuc
Autorzy:
Bakalarski, Paweł
Klepacka, Monika
Sówka, Karolina
Bojko, Izabela
Głowala, Damian
Bodecot, Bastien
Pinet Peralta, Luis M.
Powiązania:
https://bibliotekanauki.pl/articles/1033046.pdf
Data publikacji:
2019
Wydawca:
Towarzystwo Pomocy Doraźnej
Tematy:
Pulmonary auscultation
cadavers
education
learning
lung sounds
Opis:
INTRODUCTION: Lung auscultation is one of the basic physical examination tests both in the pre-hospital and hospital settings and should be performed on any patient who has problems with the respiratory system. Depending on the condition, clinicians can hear different breathing sounds. Our aim is to assess the effectiveness of lung auscultation on cadavers. MATERIAL AND METHODS: The study was conducted in October 2018, among 27 Emergency Medical Services (EMS) students at the University of Natural Sciences and Humanities in Siedlce. The research tool used in this study was prepared human cadaver. Students listened to four pulmonary fields (apices and bases) using a stethoscope. RESULTS: The study included 27 students with an average age of 21.76 (SD ± 3.20). The average auscultation results were: right lung at the apex - 59.26% (SD ± 49.14), right lung at the base - 96.30% (SD ± 18.89), left lung at the apex - 40.74% (SD ± 49 , 14), left lung at the base - 77.78% (SD ± 41.57). The average satisfaction score on a scale from 1 to 5 was 4.37 points (SD ± 1.13). CONCLUSIONS: The study showed that conducting classes on mannequins is not sufficient for effective auscultation of pulmonary fields, which could probably be obtained through practice on cadavers. Students showed a high level of satisfaction with participation in the study. In order to improve the quality of students’ education and practical skills, periodic classes oncadavers should be conducted.
WSTĘP: Osłuchiwanie płuc jest jednym z podstawowych badań zarówno w warunkach przedszpitalnych jak i w trakcie hospitalizacji. Należy je wykonać u każdego pacjenta, u którego występują problemy z układem oddechowym. W zależności od obecnego schorzenia, można usłyszeć różne szmery oddechowe. Celem publikacji jest ocena efektywności osłuchiwania płuc na kadawerach. MATERIAŁ I METODY: Badanie przeprowadzono w październiku 2018 roku, wśród 27 studentów ratownictwa medycznego Uniwersytetu Przyrodniczo-Humanistycznego w Siedlcach. Narzędziem badawczym był preparat ludzkiego korpusu, który wcześniej został odpowiednio przygotowany. Studenci przy użyciu stetoskopu osłuchiwali cztery pola płucne (szczyty i podstawy). WYNIKI: W badaniu wzięło udział 27 studentów, u których średnia wieku wyniosła 21.76 (SD ± 3.20). Średnie wyniki osłuchiwania wyniosły: prawe płuco u szczytu – 59,26 % (SD ± 49,14), prawe płuco u podstawy – 96.30 % (SD ± 18,89), lewe płuco u szczytu – 40,74 % (SD ± 49,14), lewe płuco u podstawy – 77,78 % (SD ± 41,57). Średni wynik poziomu satysfakcji w skali od 1 do 5 wyniósł 4,37pkt (SD ± 1,13). WNIOSKI: Badanie wykazało, iż prowadzenie zajęć na fantomach nie jest wystarczające pod względem odpowiedniego przygotowania studentów do efektywnego osłuchiwania pól płucnych, co prawdopodobnie można by było uzyskać poprzez ćwiczenia na kadawerach. Studenci wykazali wysoki poziom satysfakcji z udziału w badaniu. Należy poszukać rozwiązań umożliwiających okresowe prowadzenie zajęć na kadawerach dla studentów w celu podnoszenia jakości ich kształcenia i umiejętności praktycznych.
Źródło:
Critical Care Innovations; 2019, 2, 3; 11-18
2545-2533
Pojawia się w:
Critical Care Innovations
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Rola przezklatkowej ultrasonografii płuc u dzieci
Role of lung ultrasound in paediatric patients
Autorzy:
Kryger, Magdalena
Kosiak, Wojciech
Powiązania:
https://bibliotekanauki.pl/articles/1033374.pdf
Data publikacji:
2014
Wydawca:
Medical Communications
Tematy:
children
lung diseases
paediatrics
transthoracic lung ultrasound
ultrasonography
ultrasonografia
przezklatkowe ultrasonograficzne badanie płuc
choroby płuc
dzieci
pediatria
Opis:
Transthoracic lung ultrasound is ultrasonographic assessment of the lungs, parietal and visceral pleura and the space between these two membranes. It is a part of chest ultrasound examination which also includes assessment of the ribs, intercostal spaces, diaphragm, heart and mediastinum. Lung ultrasound as a diagnostic tool which has been known for 30 years, but its advantages and disadvantages are not commonly known and therefore it is not routinely used by clinicians. In paediatrics, lung ultrasound has become more popular since the first decade of the 21st century. The main advantage of this method is no exposure to ionizing radiation. Transthoracic lung ultrasound can be performed in practically any conditions and repeated several times. What is more, its accessibility, reliability, accuracy and low cost compared to other methods, makes lung ultrasound the great tool for lung assessment. It can be used both for initial diagnosis and monitoring of treatment (bedside examinations are possible). In this paper, we describe the technique of lung ultrasound examination, equipment requirements, normal lung ultrasound appearance, disadvantages of the examination and lung ultrasound findings in the most common paediatric lung diseases, such as: pneumonia, pleural fluid, atelectasis, pneumothorax, bronchiolitis, pulmonary oedema and pulmonary embolism.
Przezklatkowe ultrasonograficzne badanie płuc to ultrasonograficzna ocena płuc, opłucnej ściennej, opłucnej płucnej i przestrzeni między tymi błonami. Jest częścią ultrasonograficznego badania klatki piersiowej, w którym dodatkowo ocenia się struktury powierzchowne ograniczające jamę klatki piersiowej, przeponę, śródpiersie i serce. Przezklatkowa ultrasonografia płuc jako metoda diagnostyczna chorób płuc stosowana jest od ponad 30 lat, jednakże jej zalety i ograniczenia nie są powszechnie znane i nie uzyskały jeszcze pełnej akceptacji klinicystów. Od pierwszej dekady XXI wieku badanie to staje się coraz powszechniej wykorzystywaną metodą diagnostyki obrazowej w pediatrii. Do tej pory nie udokumentowano działań niepożądanych, co więcej – jest to metoda pozbawiona szkodliwego promieniowania jonizującego. Przezklatkowe ultrasonograficzne badanie płuc można wykonać praktycznie w każdych warunkach i wielokrotnie powtarzać. Z uwagi na jego dostępność, wiarygodność i dokładność w porównaniu z metodami uznanymi za referencyjne, a także niski koszt wydaje się najlepszym badaniem służącym do oceny płuc. Może być ono wykorzystywane zarówno w procesie wstępnej diagnostyki, jak i w monitorowaniu przebiegu leczenia (możliwość wykonania badań przyłóżkowo). W artykule oprócz zagadnień dotyczących techniki badania ultrasonograficznego, wymagań sprzętowych, prawidłowego ultrasonograficznego obrazu płuc i ograniczeń badania omówiono jego rolę w diagnostyce chorób płuc u dzieci, takich jak: zapalenie płuc, płyn w jamie opłucnej, niedodma, odma opłucnowa, zapalenie oskrzelików, obrzęk płuc i zatorowość płucna.
Źródło:
Pediatria i Medycyna Rodzinna; 2014, 10, 4; 386-396
1734-1531
2451-0742
Pojawia się w:
Pediatria i Medycyna Rodzinna
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Occupational exposure to radon for underground tourist routes in Poland: Doses to lung and the risk of developing lung cancer
Autorzy:
Walczak, Katarzyna
Olszewski, Jerzy
Politański, Piotr
Zmyślony, Marek
Powiązania:
https://bibliotekanauki.pl/articles/2161885.pdf
Data publikacji:
2017-07-14
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
occupational exposure
radon
effective dose
relative risk of lung cancer
equivalent dose to lung
underground tourist routes
Opis:
Objectives Radon concentrations for 31 Polish underground tourist routes were analyzed. The equivalent dose to the lung, the effective dose and the relative risk were calculated for employees of the analyzed routes on the grounds of information on radon concentrations, work time, etc. Material and Methods The relative risk for lung cancers was calculated using the Biological Effects of Ionizing Radiation (BEIR) VI Committee model. Equivalent doses to the lungs of workers were determined using the coefficients calculated by the Kendall and Smith. The conversion coefficient proposed by the International Atomic Energy Agency (IAEA) in the report No. 33 was used for estimating the effective doses. Results In 13 routes, the effective dose was found to be above 1 mSv/year, and in 3 routes, it exceeded 6 mSv/year. For 5 routes, the equivalent dose to lungs was higher than 100 mSv/year, and in 1 case it was as high as 490 mSv/year. In 22.6% of underground workplaces the risk of developing lung cancer among employees was about 2 times higher than that for the general population, and for 1 tourist route it was about 5 times higher. The geometric mean of the relative risk of lung cancer for all workers of underground tourist routes was 1.73 (95% confidence interval (CI): 1.6–1.87). Routes were divided into: caves, mines, post-military underground constructions and urban underground constructions. Conclusions The difference between levels of the relative risk of developing lung cancer for all types of underground tourist routes was not found to be significant. If we include the professional group of the employees of underground tourist routes into the group of occupational exposure, the number of persons who are included in the Category A due to occupational exposure may increase by about 3/4. The professional group of the employees of underground tourist routes should be monitored for their exposure to radon. Int J Occup Med Environ Health 2017;30(5):687–694
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2017, 30, 5; 687-694
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-25 z 163

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