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Wyszukujesz frazę ""lung"" wg kryterium: Temat


Tytuł:
Authors’ response (April 30, 2018) to the letter to the editor concerning the paper “Histological findings and lung dust analysis as the basis for occupational disease compensation in asbestos-related lung cancer in Germany”
Autorzy:
Feder, Inke S.
Theile, Anja
Tannapfel, Andrea
Powiązania:
https://bibliotekanauki.pl/articles/2162025.pdf
Data publikacji:
2018-12-20
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
asbestos bodies
occupational disease
lung fiber burden
lung dust analysis
lung cancer
compensation
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2018, 31, 6; 849-851
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Innovations in lung cancer treatment
Autorzy:
Sieńko, Anna
Rożenek, Karolina
Nalewaj, Piotr
Bożyk, Aleksandra
Krawczyk, Paweł
Powiązania:
https://bibliotekanauki.pl/articles/1178237.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Immunotherapy
Lung cancer
Lung cancer treatment
targeted therapy
Opis:
Lung cancer is associated with one of the highest mortality rates among malignant tumors. It is the main death cause of men and women in Poland where over 15 000 men and 7 000 women die with this diagnosis annually. 1.7 million people die every year due to lung cancer in the world. Two main types of lung cancer are small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). The history of lung cancer treatment begins with surgical approach followed by addition of chemotherapy and radiotherapy, which were used either separately or in combination depending on the stage of the lung cancer. Many somatic mutations were identified and molecularly targeted therapies could have been established. One of the oldest and the best known group of molecularly targeted drugs used in lung cancer treatment are tyrosine kinase inhibitors (TKIs) of epidermal growth factor receptor (EGFR). First EGFR-TKI was gefitinib, which has been examined in clinical trials before erlotinib, afatinib, dacomitinib and osimertinib. EGFR-TKIs increased overall survival (OS) with significantly less side effects when compared to standard chemotherapy. Another group of molecularly targeted drugs are anaplastic lymphoma (ALK) kinase inhibitors such as crizotinib, alectinib and ceritinib. Another innovation which was introduced in NSCLC treatment was immunotherapy. Its effect is based on modification of immune system leading to activation of cytotoxic T lymphocytes (CTL). Currently nivolumab and pembrolizumab (anti-PD1 antibodies) as well as atezoliumab (anti-PD-L1 antibody) are being used in NSCLC patients. The discovery of innovative therapies for NSCLC patients resulted in significant extension of patients' life expectancy while minimizing the side effects of such therapy. Moreover, the quality of patients’ life was significantly improved. However, important problems still remain to be solved: overcoming the resistance in the course of molecularly targeted therapies and the lack of predictive factors that determine the effectiveness of immunotherapy.
Źródło:
World Scientific News; 2018, 93; 115-124
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Authors’ response (March 14, 2018) to the letter to the Editor concerning the paper “Histological findings and lung dust analysis as the basis for occupational disease compensation in asbestos-related lung cancer in Germany”
Autorzy:
Feder, Inke S.
Theile, Anja
Tannapfel, Andrea
Powiązania:
https://bibliotekanauki.pl/articles/2162041.pdf
Data publikacji:
2018-12-20
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
lung cancer
occupational disease
compensation
asbestos bodies
lung asbestos fiber burden
lung dust analysis
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2018, 31, 6; 841-843
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pulmonary lymphangitic carcinomatosis in the course of gastric cancer - Case report
Autorzy:
Witczak, A.
Prystupa, A.
Zamecka, M.O.
Bilan, A.
Krupski, W.
Mosiewicz, J.
Powiązania:
https://bibliotekanauki.pl/articles/3002.pdf
Data publikacji:
2014
Wydawca:
Instytut Medycyny Wsi
Tematy:
pulmonary lymphangitic carcinomatosis
gastric cancer
interstitial lung disease
lung
Opis:
Pulmonary lymphangitic carcinomatosis is a special type of diffuse metastasis of carcinoma in the lymphatic vessels of the lungs. Lymphangitic carcinomatosis is commonly observed in malignancies of the breast, lung, pancreas, colon and cervix as a strong marker for poor prognosis. Presenting with common respiratory symptoms, it may be easily misdiagnosed as other pulmonary interstitial diseases. Pulmonary lymphangitic carcinomatosis is a rare manifestation of metastatic gastric cancer. The presented case describes a patient with pulmonary lymphangitic carcinomatosis in the course of stomach cancer. The primary diagnosis was established based on the exclusion of other interstitial lung diseases, with the use of imaging techniques as well as biochemical, microbiological and cytological findings. The patient’s general condition was very severe, rendering him bedridden and therefore not eligible for any treatment, including chemotherapy. He died suddenly before final verification of the diagnosis. Pulmonary lymphangitic carcinomatosis should be suspected in patients with advanced gastric cancer, presenting with symptoms and signs of respiratory disease. Imaging techniques are mostly helpful to establish the diagnosis.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2014, 08, 2
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Histological findings and lung dust analysis as the basis for occupational disease compensation in asbestos-related lung cancer in Germany
Autorzy:
Feder, Inke S.
Theile, Anja
Tannapfel, Andrea
Powiązania:
https://bibliotekanauki.pl/articles/2159908.pdf
Data publikacji:
2017-12-21
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
occupational disease
lung asbestos fiber burden
asbestos bodies
lung cancer
lung dust analysis
compensation
Opis:
Objectives This study has researched the significance of histologically raised findings and lung dust analyses in the context of claiming the recognition of and thus compensation for an asbestos-associated occupational disease. Material and Methods For this approach, all findings from the German Mesothelioma Register in 2015 that included lung dust analyses were evaluated and were compared with information on asbestos fiber exposure at work based on fiber years, and with the results of radiological findings. Results For 68 insured persons, recognition of an asbestos-induced lung disease according to Section 4104 of the German Ordinance on Occupational Diseases (Berufskrankheitenverordnung – BKV) could be recommended solely on the basis of the histological examinations of lung tissues and complementary lung dust analyses. Neither did the calculation of the cumulative asbestos dust exposure at work yield 25 fiber years, nor could bridge findings (e.g., plaques) be identified. In addition, the autopsies of 12 patients revealed plaques that had not been diagnosed during radiological examinations. These results show that – irrespective of the prescribed working techniques and radiological diagnosis – pathological/anatomical and histological diagnostics are often the only way for the insureds to demonstrate the causal connection between asbestos and their disease. Even after long intervals of up to 40 years post last exposure, the asbestos fibers would still be easily detectable in the lung tissues evaluated. Conclusions Whenever suitable tissue is available, it should be examined for mild asbestosis with the aid of a lung dust analysis. Otherwise there is a risk that an occupational disease is wrongfully rejected. In the context of health insurance, the lung dust analysis and the resulting proof of the presence of asbestosis often constitute one option of providing evidence of an occupational disease. Int J Occup Med Environ Health 2018;31(3):293–305
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2018, 31, 3; 293-305
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Is a linear probe helpful in diagnosing diseases of pulmonary interstitial spaces?
Czy głowica liniowa jest pomocna w diagnostyce chorób zajmujących przestrzeń śródmiąższową płuc?
Autorzy:
Buda, Natalia
Kosiak, Wojciech
Powiązania:
https://bibliotekanauki.pl/articles/1033448.pdf
Data publikacji:
2017
Wydawca:
Medical Communications
Tematy:
interstitial lung disease
Opis:
In a lung ultrasound examination, interstitial lung lesions are visible as numerous B-line artifacts, and are best recorded with the use of a convex probe. Interstitial lung lesions may result from many conditions, including cardiogenic pulmonary oedema, non-cardiogenic pulmonary oedema, or interstitial lung disease. Hence difficulties in the differential diagnostics of the above clinical conditions. This article presents cases of patients suffering from interstitial lung lesions discovered in the course of lung ultrasound examination. The patients were examined with a 3.5–5.0 MHz convex probe and a 7.0–11.0 MHz linear probe. Ultrasound images have been analysed, and differences in the imaging with both probes in patients with interstitial lung lesions have been detailed. The use of a linear probe in patients with interstitial lung lesions (discovered with a convex or a micro-convex probe) provides additional information on the source of the origin of the lesions.
Zmiany śródmiąższowe płuc w badaniu ultrasonograficznym prezentują się jako liczne artefakty linii B, rejestrowane najlepiej przy pomocy sondy konweksowej. Przyczyn zmian śródmiąższowych płuc może być wiele: kardiogenny obrzęk płuc, niekardiogenny obrzęk płuc oraz zmiany w przebiegu śródmiąższowych chorób płuc. Powoduje to trudności w diagnostyce różnicowej powyższych stanów klinicznych. W artykule przedstawiono serię przypadków pacjentów, u których w badaniu ultrasonograficznym płuc stwierdzono zmiany śródmiąższowe płuc. Badania wykonano przy pomocy sondy konweksowej (3,5–5,0 MHz) oraz liniowej (7,0–11,0 MHz). Dokonano analizy obrazów ultrasonograficznych oraz wskazano różnice w obrazowaniu obiema głowicami w grupie pacjentów ze zmianami śródmiąższowymi w płucach. Zastosowanie sondy liniowej u pacjentów ze stwierdzonymi (przy pomocy sondy konweksowej lub mikrokonweksowej) zmianami śródmiąższowymi płuc wnosi nowe informacje na temat źródła ich pochodzenia. Artykuł w wersji polskojęzycznej jest dostępny na stronie http://jultrason.pl/index.php/wydawnictwa/volume-17-no-69
Źródło:
Journal of Ultrasonography; 2017, 17, 69; 136-141
2451-070X
Pojawia się w:
Journal of Ultrasonography
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hyponatremia secondary to the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) during the course of lung cancer. A case report
Autorzy:
Radzka, Agnieszka
Fałkowska, Urszula
Sławiński, Aleksander
Ryczkowski, Aleksander
Obel, Ewa
Lewicki, Marcin
Powiązania:
https://bibliotekanauki.pl/articles/454668.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
hyponatremia
SIADH
lung cancer
Opis:
Introduction. Hyponatremia is a frequently observed electrolyte disorder among patients with cancer. In 1957, Schwartz et al. reported the first case of a patient with hyponatremia due to SIADH, secondary to lung cancer. From that moment on, there has been data published that indicates patients with SIADH are less responsive to chemotherapy, have greater predisposition to central nervous system metastases and are often characterized by an advanced stage of cancer during time of diagnosis. Hyponatremia has many possible causes, and the differential diagnosis can pose a challenge. Aim. The aim of the study was to consider the occurrence of secondary hyponatremia in the course of cancer and the significance of this disorder in the prognosis of the disease. Methods. An analysis of the clinical history of the patient and a review of available literature. Results. A 66-year old patient with hyponatremia was admitted to the Department of Endocrinology, and lung cancer was determined as the cause of the aforementioned electrolyte disorder. Conclusion. SIADH secondary to cancers should be included in a differential diagnosis of every case of hyponatremia of undetermined etiology.
Źródło:
European Journal of Clinical and Experimental Medicine; 2018, 2; 163-167
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pulmonary actinomycosis - the great imitator
Autorzy:
Grzywa-Celińska, A.
Emeryk-Maksymiuk, J.
Szmigin-Millanowska, K.
Czekajska-Cherhab, E.
Milanowski, J.
Powiązania:
https://bibliotekanauki.pl/articles/2081602.pdf
Data publikacji:
2018
Wydawca:
Instytut Medycyny Wsi
Tematy:
actinomycosis
imitator
lung cancer
Opis:
Pulmonary localisation represents only 15% of all cases of actinomycosis. The clinical symptoms and radiological changes of this disease are non-specific and sometimes it can be misdiagnosed, usually as tuberculosis, lung cancer or lung abscess. In the reported case, what might look like the lung cancer, finally turned out to be actinomycosis. The interesting case is presented of lung actinomycosis in a 77-year-old farmer, admitted to the Department of Pneumonology, Oncology and Allegology in Lublin due to a massive haemoptysis. CT scan of the chest showed, apart from other changes, the spicular consolidation in the right lung which aroused oncology vigilance. The diagnostic path, which was a real medical challenge, led to the diagnosis of actinomycosis. The process of diagnosis and consequent treatment, which led to the complete regression of clinical and radiological changes, is presented.
Źródło:
Annals of Agricultural and Environmental Medicine; 2018, 25, 2; 211-212
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Thiram - toxic inhalational lung injury
Autorzy:
Siwiec, J.
Siek, E.
Grzywa-Celińska, A.
Mackiewicz, B.
Czekajska-Chehab, E.
Powiązania:
https://bibliotekanauki.pl/articles/2085136.pdf
Data publikacji:
2019
Wydawca:
Instytut Medycyny Wsi
Tematy:
thiram
lung injury
inhalation
Opis:
Introduction. Thiram, a fungicides, is widely used on seeds and as foliar agent on turf, vegetables and fruit. It is also used in the rubber industry as a vulcanization accelerator. When absorbed through the respiratory system, it is rapidly metabolised to dimethylthiocarbamate and carbon disulphide, causing noxious effects. A brief review is presented of the literature, centering on the interesting case of a 45-year-old woman admitted to the hospital suffering from acute respiratory failure. Results. Computer tomography in angiographic option (angio-CT) showed an extensive, irregular area of ground glass in both upper lobes and apical segments of the lower lobes of the lungs. A significant enlargement of both atria was also described. There was no improvement after cardiac treatment and patient was transferred to the pulmonary department where she was succesfully treated with systemic glucocortycosteroids. The patient remains under the supervision of the pulmonary out-patient department.
Źródło:
Annals of Agricultural and Environmental Medicine; 2019, 26, 4; 672-673
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Combined analysis of onco-epidemiological studies of the relationship between lung cancer and indoor radon exposure
Autorzy:
Yarmoshenko, Ilia V.
Malinovsky, Georgy P.
Powiązania:
https://bibliotekanauki.pl/articles/146354.pdf
Data publikacji:
2020
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
lung cancer
radon
relative risk
Opis:
Objectives: Recent results of epidemiological and medical statistics studies of lung cancer and indoor radon in different regions of the world make a relevant new combined analysis of residential exposure health effects. In particular, new data were obtained by means of a meta-analysis of case-control studies as well as taking into account a confounding effect of human papillomavirus infection in studies of geographically aggregated data. Materials and methods: Two sources of epidemiological data are considered: (1) studies of ecological design and (2) case-control studies. Ecological studies included the analysis performed for the USA counties and Russian oblasts with adjusting for the main confounders. Data on the case-control studies were gained from the meta-analysis of 31 individual studies with a weighting of obtained odds ratios according to the quality of radon exposure reconstruction and size of the reference group. Estimations of lung cancer excess relative risk (ERR) associated with indoor radon exposure are combined. Results: Two types of epidemiological study design provided generally consistent EER estimations. The combined value of ERR due to radon exposure is 0.14 (90% CI: 0.10–0.18) per 100 Bq/m3 . Conclusion: Available geographically aggregated data in regions of Russia and the United States and the meta-analysis of case-control studies conducted in a large number of countries confirm the association of lung cancer with indoor radon exposure.
Źródło:
Nukleonika; 2020, 65, 2; 83-88
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł

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