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Wyszukujesz frazę "mitochondrial DNA" wg kryterium: Wszystkie pola


Wyświetlanie 1-49 z 49
Tytuł:
Properties of mitochondrial DNA polymerase in mitochondrial DNA synthesis in yeast
Autorzy:
Biswas, Tapan
Sengupta, Pritam
Green, Renee
Hakim, Paul
Biswas, Bani
Sen, Sribir
Powiązania:
https://bibliotekanauki.pl/articles/1045221.pdf
Data publikacji:
1995
Wydawca:
Polskie Towarzystwo Biochemiczne
Źródło:
Acta Biochimica Polonica; 1995, 42, 3; 317-324
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Organisation of Unionid mitochondrial DNA
Autorzy:
Soroka, M.
Powiązania:
https://bibliotekanauki.pl/articles/83417.pdf
Data publikacji:
2010
Wydawca:
Uniwersytet Mikołaja Kopernika. Wydział Biologii i Ochrony Środowiska. Stowarzyszenie Malakologów Polskich
Źródło:
Folia Malacologica; 2010, 18, 3
1506-7629
Pojawia się w:
Folia Malacologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mitochondrial DNA in pediatric leukemia patients
Autorzy:
Kodroń, Agata
Ghanim, Magda
Krawczyk, Katarzyna
Stelmaszczyk-Emmel, Anna
Tońska, Katarzyna
Demkow, Urszula
Bartnik, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1038705.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
pediatric ALL
mtDNA
chemotherapy
Opis:
Numerous studies of mitochondrial DNA (mtDNA) in cancer have shown differences between mtDNA sequences in tumor and normal tissue and at various stages of cancer treatment in the same patient. However, there is little data on acute lymphoblastic leukemia (ALL), the most common type of leukemia in children. In this study we compared mitochondrial sequence variation in the D-loop region and in 5 genes of mtDNA in bone marrow samples of 6 pediatric patients with ALL at various stages of therapy. We found several common polymorphisms and one variant at position 3688 whose level varied during leukemia treatment. Our results suggest that mitochondrial DNA mutations, whose levels change during patient treatment, could be potential biomarkers for monitoring treatment efficacy and disease progression.
Źródło:
Acta Biochimica Polonica; 2017, 64, 1; 183-187
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Organisation of mitochondrial DNA in dreissenid bivalves
Autorzy:
Soroka, M.
Burzynski, A.
Rymaszewska, A.
Powiązania:
https://bibliotekanauki.pl/articles/84655.pdf
Data publikacji:
2012
Wydawca:
Uniwersytet Mikołaja Kopernika. Wydział Biologii i Ochrony Środowiska. Stowarzyszenie Malakologów Polskich
Tematy:
mitochondrial DNA
bivalve
Dreissenidae
genome
Cristaria plicata
Placopecten magellanicus
gene number
Dreissena
Dreissena polymorpha
Dreissena bugensis
Źródło:
Folia Malacologica; 2012, 20, 1
1506-7629
Pojawia się w:
Folia Malacologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Fluorescent in situ hybridization of mitochondrial DNA and RNA
Autorzy:
Alán, Lukáš
Zelenka, Jaroslav
Ježek, Jan
Dlasková, Andrea
Ježek, Petr
Powiązania:
https://bibliotekanauki.pl/articles/1040297.pdf
Data publikacji:
2010
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
molecular beacon fluorescent hybridization probes
nucleoids of mitochondrial DNA
confocal microscopy
transcription and replication intermediates
mitochondrial DNA and RNA
Opis:
To reveal nucleic acid localization in mitochondria, we designed molecular beacon fluorescent probes against: i) the light strand complementary to ND5 mitochondrial DNA (mtDNA) gene (annealing also to corresponding mRNA); ii) displacement (D) loop 7S DNA (annealing also to parallel heavy strand mtDNA and corresponding light strand transcript); iii) the proximal D-loop heavy strand displaced by the light strand promoter minor RNA. Confocal microscopy demonstrated ND5 probe spreading (less for other probes) in mitochondrial reticulum tubules but upon RNase A treatment all probes contoured mtDNA nucleoid localization. DNase I spread the signal over mitochondrial tubules. Future applications are discussed.
Źródło:
Acta Biochimica Polonica; 2010, 57, 4; 403-408
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mitochondrial DNA-based diagnostic molecular markers for freshwater bivalves
Autorzy:
Soroka, M.
Grygienczo-Razniewska, E.
Powiązania:
https://bibliotekanauki.pl/articles/84024.pdf
Data publikacji:
2005
Wydawca:
Uniwersytet Mikołaja Kopernika. Wydział Biologii i Ochrony Środowiska. Stowarzyszenie Malakologów Polskich
Opis:
The study was carried out on 9 species of freshwater bivalves (Dreissena polymorpha, D. bugensis, Unio crassus, U. pictorum, U. tumidus, Anodonta anatina, A. cygnea, A. woodiana, and Pseudanodonta complanata). The mitochondrial COI gene studied with PCR-RFLP and 6 restriction enzymes (ScrFI, Csp6I, BsiZI, EcoRI, BamHI and AluI) showed the absence of individual variability within each species studied. The genetic variability of the COI involved differences at the species, genus, and family level, depending on the restriction enzyme used. Four restriction enzymes (ScrFI, Csp6I, BsiZI and AluI) proved efficient in differentiating between D. polymorpha and D. bugensis as well as in identifying the three Unio species (Csp6I and AluI), U. crassus, and P. complanata (ScrFI and AluI). EcoRI and AluI made it possible to identify A. anatina and P. complanata. Two (for EcoRI), 3 (for Csp6I, BsiZI), 5 (for ScrFI) and 9 (for AluI) unique genotypes that occurred in a single species each were observed; the enzymes may therefore be regarded as species-specific markers. Only restriction enzyme AluI can differentiate between A. cygnea and A. woodiana.
Źródło:
Folia Malacologica; 2005, 13, 4
1506-7629
Pojawia się w:
Folia Malacologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mitochondrial DNA sequence in phylogenetic studies on lymnaeid snails
Autorzy:
Rybska, E.
Pacak, A.
Szwykowska-Kulinska, Z.
Lesicki, A.
Powiązania:
https://bibliotekanauki.pl/articles/84362.pdf
Data publikacji:
2002
Wydawca:
Uniwersytet Mikołaja Kopernika. Wydział Biologii i Ochrony Środowiska. Stowarzyszenie Malakologów Polskich
Źródło:
Folia Malacologica; 2002, 10, 1
1506-7629
Pojawia się w:
Folia Malacologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Characteristics of mitochondrial DNA of unionid bivalves (Mollusca: Bivalvia: Unionidae). I. Detection and characteristics of doubly uniparental inheritance (DUI) of unionid mitochondrial DNA
Autorzy:
Soroka, M.
Powiązania:
https://bibliotekanauki.pl/articles/84282.pdf
Data publikacji:
2010
Wydawca:
Uniwersytet Mikołaja Kopernika. Wydział Biologii i Ochrony Środowiska. Stowarzyszenie Malakologów Polskich
Opis:
Doubly Uniparental Inheritance (DUI), a peculiar way of inheritance of mitochondrial DNA in animals, has been detected in seven families of marine and freshwater bivalves, including Unionidae. DUI involves two independently inherited mitochondrial genomes: maternal (F genome) and paternal (M genome), which show different tissue localisation and wide genetic variation. F genomes occur in somatic tissues of both sexes and are inherited maternally (Strict Maternal Inheritance, SMI). M genomes are located in male germ cells and transmitted to next generations along the male lineage, i.e. from fathers to male offspring. The objective of this study was detection of M genomes and characteristics of DUI in unionid bivalves from Poland, based on sequential analyses of seven mitochondrial genes. This is the study to analyse F and M haplotypes at intra- and interspecific level in seven species of freshwater mussels. DUI was first observed in species of the genus Unio (U. crassus, U. pictorum and U. tumidus), and the best M haplotype marker was gene cox1. In the studiem bivalves F and M sequences showed a similar intraspecific variation, with differences among the genes. Three tRNA genes showed the smallest (ca. 20%) nucleotide variation, followed by the gene coding for RNA for the small ribosomal subunit, srRNA (24%); a significantly greater variation (exceeding 30%) was recorded for protein-coding genes (cox1, cytb) and the gene coding for RNA for the large ribosomal subunit, lrRNA. Interspecific variation of F sequences of the studied unionids ranged from 5% for tRNAs to18% for cytb. Higher values were observed for M sequences: from 7% for tRNAs to19% for cox1. The Chinese mussel occurring in Poland, despite the morphology-based identification as Anodonta / Sinanodonta woodiana, proved to be genetically more similar to A. arcaeformis than toAsian specimens of A. woodiana. Phylogenetic analyses showed that in the genus Unio the youngest species were U. pictorum and U. mancus, and the earliest species was U. tumidus showing the greatest genetic distinctness.
Źródło:
Folia Malacologica; 2010, 18, 4
1506-7629
Pojawia się w:
Folia Malacologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mitochondrial DNA variability in Gyimesi Racka and Turcana sheep breeds
Autorzy:
Kusza, Szilvia
Zakar, Erika
Budai, Csilla
Cziszter, Ludovic-Toma
Padeanu, Ioan
Gavojdian, Dinu
Powiązania:
https://bibliotekanauki.pl/articles/1039104.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
farm animal conservation
genetic diversity
mtDNA
trans-boundary breeds
Zackel group
Opis:
The current knowledge and documentation on the origins and relationship between Gyimesi Racka reared in Hungary and the Romanian Turcana is rather controversial. Lack of information and scientific reliable proofs for the divergent theories found in the two countries motivated us to implement a trial using molecular methods to assess the genetic distance and diversity in the two breeds. Hair follicles were collected from Gyimesi Racka (2 phenotypes) and from Turcana (6 ecotypes). The 599 bp segment of the D-loop region of the mitochondrial DNA was sequenced. Altogether, 42 haplotypes were identified, while 23 were found in both populations. Populations were highly diverse according to the haplotype and nucleotide diversity indices. AMOVA analysis showed that most of the variation was observed within populations (98%), indicating a weak genetic structure between the two breeds. Animals were grouped into seven groups based on their phenotype; however genetic distances among them were also low. Tajima's D, Fu's Fs, goodness-of-fit statistics, mismatch distribution and network analysis suggested recent demographic expansion. Current comprehensive mtDNA study indicates that there is very low level of genetic differentiation between the Gyimesi Racka and Turcana populations therefore they are de facto one trans-boundary breed.
Źródło:
Acta Biochimica Polonica; 2015, 62, 2; 273-280
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analysis of ancient mitochondrial DNA of the Baltic Sea sturgeon (Acipenser sp.)
Autorzy:
Fopp-Bayat, D.
Ciesielski, S.
Luczyński, M.
Powiązania:
https://bibliotekanauki.pl/articles/363174.pdf
Data publikacji:
2005
Wydawca:
Uniwersytet Warmińsko-Mazurski w Olsztynie
Tematy:
jesiotr
historyczny mtDNA
filogeneza molekularna
gen cytochromu b
Morze Bałtyckie
Acipenser baeri
Acipenser oxyrinchus
Acipenser sturio
ancient mtDNA
cytochrome b gene
molecular phylogeny
Opis:
Genetic relatedness between Baltic Sea sturgeon (Acipenser sturio L.) specimens caught in different geographic areas is not clear. According to previous studies, fish captured in different locations within the historic area of A. sturio habitation are genetically different to each other. We have examined a fragment (191 base pairs) of mitochondrial cytochrome b gene of four specimens of A. sturio found in Poland: three fish were preserved in museums of natural history and the bone of one fish was from an archaeological site. DNA sequences of the three museum samples were identical, whereas the DNA sequence of the archaeological sample differed in the 918 position of the cytochrome b gene. All the analyzed DNA fragments were similar to those of Acipenser baeri and genetically distant to Acipenser sturio and A. oxyrinchus.
Źródło:
Environmental Biotechnology; 2005, 1, 1; 29-33
1734-4964
Pojawia się w:
Environmental Biotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
RNA-seq reveals differentially expressed genes in cucumber MSC lines possessing mitochondrial DNA rearrangements
Autorzy:
Mroz, T.
Pryszcz, L.
Skarzynska, A.
Kielkowska, A.
Havey, M.
Bartoszewski, G.
Powiązania:
https://bibliotekanauki.pl/articles/80502.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
conference
cucumber
gene expression
mitochondrial DNA
transcriptome
wild-type line
oxidoreductase
rearrangement
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Nuclear and mitochondrial genome responses in HeLa cells treated with inhibitors of mitochondrial DNA expression
Autorzy:
Piechota, Janusz
Szczęsny, Roman
Wolanin, Kamila
Chlebowski, Aleksander
Bartnik, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1041204.pdf
Data publikacji:
2006
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
thiamphenicol
mtDNA depletion
HeLa
dideoxycytidine
mitochondrial biogenesis
ethidium bromide
Opis:
The influence of mutations in the mitochondrial DNA (mtDNA) on the bioenergetic metabolism of the cell is still poorly understood. Many of the mutations in the mtDNA affect the expression of the mitochondrial genome. Investigations on cells from patients are not easy, especially as the mitochondrial DNA is heteroplasmic and this state is changed in culture. Moreover, the nuclear background and the mitochondrial haplotype may affect the behaviour of cells. Transfer of patient mitochondria to rho zero cell lines is also not optimal as these cells in general have many nuclear changes which may also affect cell behaviour. Thus, we decided to use inhibitors of mitochondrial genome expression, such as thiamphenicol, ethidium bromide and dideoxycytidine to investigate the bioenergetic metabolism of HeLa cells. We found that oxidative phosphorylation and glycolysis participate equally in ATP production in HeLa cells and that decreased activity of the respiratory chain leads to increased glycolysis and the reduction of cell growth. Insufficient ATP production in the oxidative phosphorylation process was not compensated by increased proliferation of the mitochondria. However, we were able to show that there are some mechanisms compensating limited expression of the mitochondrial genome within the mitochondria. Experiments with dideoxycytidine revealed that 10-fold decrease of the mtDNA copy number resulted in almost normal activity of cytochrome c oxidase. We found that mtDNA depletion is compensated mostly on the level of RNA metabolism in the mitochondria. Thus, our results are in agreement with the hypothesis that transcription initiation rather than mtDNA copy number is a rate limiting factor for expression of the mitochondrial genome.
Źródło:
Acta Biochimica Polonica; 2006, 53, 3; 485-495
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of the suitability of mitochondrial DNA for species identification of microtraces and forensic traces
Autorzy:
Natonek-Wiśniewska, Małgorzata
Krzyścin, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/1038564.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
biological traces
forensic DNA analysis
species identification of forensic DNA
species identification of biological traces
mtDNA
Opis:
The objective of the study was to demonstrate how mitochondrial DNA (mtDNA) can be used to determine the species origin of animal microtraces. The study included pieces of cat and dog hair without the root, a fragment of cooked chicken bone (0.1g), three goose down samples (0.028 g), a pork swab, a pork scratching (5×5×5 mm), and pork lard (0.22 g). DNA was isolated from all of these samples using the method appropriate for the particular source material. The extracts had DNA concentration exceeding 5.4 ng/µl with A260/280 purity range of 1.14-1.88. Next, the samples were subjected to PCR and real-time PCR with species-specific primers and primers complementary to mitochondrial DNA (mtDNA). Control reactions based on the amplification of eukaryotic-specific fragment (18S rRNA) were additionally performed. PCR and real-time PCR products for detection of species-specific mtDNA were obtained for all templates, whereas during the detection of eukaryote DNA no product was obtained for dog and cat hair only. The poor quality of the obtained DNA did not prevent the analysis. The results showed that mitochondrial DNA is suitable for identification of small or highly processed samples, in which genomic DNA often cannot be analyzed.
Źródło:
Acta Biochimica Polonica; 2017, 64, 4; 705-708
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Biotechnology in the restoration of extinct animal species. An analysis of genomic and mitochondrial DNA of aurochs
Autorzy:
Lipinski, D.
Przystalowska, H.
Szalata, M.
Zeyland, J.
Wielgus, K.
Frackowiak, H.
Dzieduszycki, A.M.
Ryba, M.S.
Slomski, R.
Powiązania:
https://bibliotekanauki.pl/articles/80741.pdf
Data publikacji:
2011
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
analysis
animal species
aurochs
biotechnology
description
extinct species
genomic DNA
history
mitochondrial DNA
museum
restoration
skeleton
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2011, 92, 1
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Variation patterns of mitochondrial DNA of Abies alba Mill. in suture zones of postglacial migration in Europe
Autorzy:
Gomory, D
Longauer, R.
Liepelt, S.
Ballian, D.
Brus, R.
Kraigher, H.
Parpan, V.I.
Parpan, T.V.
Paule, L.
Stupar, V.I.
Ziegenhagen, B.
Powiązania:
https://bibliotekanauki.pl/articles/58447.pdf
Data publikacji:
2004
Wydawca:
Polskie Towarzystwo Botaniczne
Tematy:
postglacial migration
mitochondrial DNA
Abies alba
suture zone
silver fir
Europe
Opis:
Thirty silver fir populations originating from the putative suture zones of the postglacial recolonization (Slovenia, Bosnia and Hercegovina, Ukraine) were studied using a mitochondrial nad5-4 gene marker. The geographical distribution of mtDNA haplotypes in the Ukrainian Carpathians and their northern foothills indicates a very recent meeting of migration streams arriving from the Romanian Carpathians and Central Europe. In the western part of the Balkan Peninsula, two counterparallel migration streams are the most plausible explanation of the pattern observed. The haplotype typical for the Balkan Peninsula predominates along the Adrian coast, whereas the CentralEuropean haplotype is more represented in the inland.
Źródło:
Acta Societatis Botanicorum Poloniae; 2004, 73, 3
0001-6977
2083-9480
Pojawia się w:
Acta Societatis Botanicorum Poloniae
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Detection of recombinant mitochondrial genomes: Implications for the mechanism of mtDNA inheritance in mussel Mytilus
Autorzy:
Filipowicz, M.
Burzyński, A.
Wenne, R.
Powiązania:
https://bibliotekanauki.pl/articles/363232.pdf
Data publikacji:
2008
Wydawca:
Uniwersytet Warmińsko-Mazurski w Olsztynie
Tematy:
DNA mitochondrialne
rekombinacja
Mytilus
mitochondrial DNA
recombination
Opis:
Recombination plays a fundamental role in the creation of biodiversity. It is the mechanism inducing formation of rearrangements within the genomes which, beside mutations, are the major source of genetic variation. In the process of recombination a single or double DNA strand is broken and rejoined with unassociated DNA fragments. There are several types of recombination: homologous recombination, sitespecific recombination and transposition. Within mitochondrial genomes, inter- and intra-molecular recombination can occur. Except for intramolecular recombination of mtDNA, the other types of recombination always result in the creation of mosaic genomes. However, in the natural populations mtDNA recombination is detected extremely rarely. It is caused by the clonal inheritance of mitochondrial genomes and consequential lack of sufficient divergence between parental mitochondrial molecules. Mussels of the genus Mytilus possess two types of mitochondrial genomes inherited from males and females, respectively, and their mode of mtDNA inheritance is called doubly uniparental inheritance (DUI). The presence of two highly diverged parental molecules gives the opportunity for detection of recombinant variants. This feature of Mytilus mtDNA can be broadly exploited in the search for and characteristics of recombinant sequences. Apart from the high level of sequence divergence, fusion of mitochondria and appropriate enzymatic toolkit are principal requirements for the occurrence of recombination. The majority of phylogenetic and demographic analysis based on mtDNA assumes the lack of recombination. If this assumption turned out to be erroneous, previous analyses would be weakened. Recombination is associated with DUI abnormalities, e.g. masculinization of mitochondrial genomes. It may even lead to the breakdown of DUI system resulting in the new, unidentified mode of mtDNA inheritance in mussel Mytilus that might be regulated by stochastic events.
Źródło:
Environmental Biotechnology; 2008, 4, 2; 54-59
1734-4964
Pojawia się w:
Environmental Biotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Human lipoprotein lipase deficiency: does chronic dyslipidemia lead to increased oxidative stress and mitochondrial DNA damage in blood cells?
Autorzy:
Ven Murthy, M.
Julien, Pierre
Singh, Preman
Levy, Emile
Powiązania:
https://bibliotekanauki.pl/articles/1045189.pdf
Data publikacji:
1996
Wydawca:
Polskie Towarzystwo Biochemiczne
Źródło:
Acta Biochimica Polonica; 1996, 43, 1; 227-240
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Searching for association of the CAG repeat polymorphism in the mitochondrial DNA polymerase gamma gene (POLG) with colorectal cancer
Autorzy:
Linkowska, Katarzyna
Jawień, Arkadiusz
Marszałek, Andrzej
Skonieczna, Katarzyna
Grzybowski, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1039019.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
POLG gene
CAG repeat
colorectal cancer
somatic mutations
Opis:
Mitochondrial DNA polymerase gamma (POLG) is the only DNA polymerase involved in maintaining the mitochondrial genome. Recent studies demonstrated an association of CAG repeat polymorphism in the second exon of POLG gene with the risk of cancer. We investigated the CAG repeat variability in the POLG gene in tumor and non-tumor tissues from colorectal cancer patients and in DNA samples isolated from blood obtained from age-matched healthy persons. Somatically occuring CAG-repeat alterations in cancer tissues have been observed in 10% of patients, but no association has been found between the CAG repeat variants in the POLG gene and colorectal cancer risk.
Źródło:
Acta Biochimica Polonica; 2015, 62, 3; 625-627
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Changes in accumulation of heteroplasmic mitochondrial DNA and frequency of recombination via short repeats during plant lifetime in Phaseolus vulgaris
Autorzy:
Woloszynska, Magdalena
Gola, Edyta
Piechota, Janusz
Powiązania:
https://bibliotekanauki.pl/articles/1039695.pdf
Data publikacji:
2012
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Phaseolus vulgaris
sublimons
heteroplasmy
quantitative real-time PCR
plant mitochondrial genome
mtDNA recombination
Opis:
Recombination via short repeats in plant mitochondrial genomes results in sublimons - DNA molecules with a copy number much lower compared to the main mitochondrial genome. Coexistence of stoichiometrically different mitotypes, called heteroplasmy, plays an important evolutionary role, since sublimons occasionally replace the main genome resulting in a new plant phenotype. It is not clear, how frequency of recombination and sublimon production is regulated and how it is related to changes in the quantity of the main genome and sublimons. We analyzed the accumulation of two recombining main genome sequences and two resulting sublimons in apical meristems, undifferentiated tissues and leaves of different age of Phaseolus vulgaris. Copy numbers of the main genome sequences varied greatly depending on tissue type and organ age while accumulation of sublimons remained much more stable. Although the overall accumulation of plant mtDNA decreased with the leaf age, the quantity of sublimons increased relative to the main genome indicating a higher frequency of recombination via the short 314 bp repeat. Recombination was symmetrical in young developing leaves while in senescent tissues it shifted towards asymmetric events resulting in overrepresentation of one product. We propose that during plant lifetime replication and recombination frequencies change oppositely sustaining heteroplasmic compositions of the genome, which are favorable for inheritance and maintenance of complex plant mtDNA.
Źródło:
Acta Biochimica Polonica; 2012, 59, 4; 703-709
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mitochondrial DNA transmission in the hybridization and introgression zone of Mytilus edulis and M.Trossulus in the Baltic and Danish straits
Autorzy:
Kijewski, T.
Wenne, R.
Powiązania:
https://bibliotekanauki.pl/articles/83498.pdf
Data publikacji:
2000
Wydawca:
Uniwersytet Mikołaja Kopernika. Wydział Biologii i Ochrony Środowiska. Stowarzyszenie Malakologów Polskich
Źródło:
Folia Malacologica; 2000, 08, 4
1506-7629
Pojawia się w:
Folia Malacologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Heteroplasmy analysis in the Polish patients with 11778A mutation responsible for Leber hereditary optic neuropathy.
Autorzy:
Mroczek-Tońska, Katarzyna
Ratajska, Dorota
Guillot, Cecile
Sąsiek, Maria
Ambroziak, Anna
Lubos, Leszek
Bartnik, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1043837.pdf
Data publikacji:
2002
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
11778A mutation
mitochondrial DNA
human
Leber hereditary optic neuropathy
Opis:
We have analysed the heteroplasmy level in 11 individuals from 3 families harbouring the mitochondrial 11778A mutation responsible for Leber hereditary optic neuropathy using last cycle hot PCR. The mutation level exceeded 90% both in affected and in unaffected individuals. We also checked whether any of the families belonged to the J haplogroup of mitochondrial DNA and obtained a negative result.
Źródło:
Acta Biochimica Polonica; 2002, 49, 1; 257-262
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
W poszukiwaniu Piastów
In search of the Piasts
Autorzy:
Handschuh, Luiza
Stolarek, Ireneusz
Juras, Anna
Zeńczak, Michał
Marcinkowska-Swojak, Małgorzata
Myszka, Anna
Trzciński, Dawid
Losik-Sidorska, Aleksandra
Wojtczak, Jakub
Philips, Anna
Różański, Artur
Dębski, Artur
Kozłowski, Piotr
Matla, Marzena
Dobosz, Józef
Jasiński, Tomasz
Piontek, Janusz
Kóčka-Krenz, Hanna
Figlerowicz, Marek
Powiązania:
https://bibliotekanauki.pl/articles/697389.pdf
Data publikacji:
2016
Wydawca:
Uniwersytet Opolski
Tematy:
The Piasts
genetic tests
DNA sequencing
ancient DNA (aDNA)
mitochondrial DNA (mt DNA)
Y chromosome
Opis:
The origin of the Piast dynasty is a matter of lively discussions and disputes. At least a few controversial hypotheses exist, but their credibility is difficult to assess due to the scarcity of written as well as material sources, especially from the time of Polish state formation. Life sciences, however, can support history and archeology. Application of genetic tests, used earlier mainly in forensic laboratories, enabled identification of the remains of King Richard III, the Romanov dynasty members and Nicolaus Copernicus. Contemporary DNA studies, based on next generation DNA sequencing, outreach the narrow area of known markers such as mitochondrial DNA (mtDNA) and selected regions of Y chromosome. Although ancient DNA (aDNA), extracted from remains, is usually highly degraded and contaminated with genetic material of microorganisms, there are methods which allow for the analysis of such material and retrieval of information about origin, kinship and some phenotypic features of an individual. Genetic studies of the Piast dynasty, a subject of our research project, have to deal with numerous difficulties. In or der to gain access to bone samples, we need to meet a number of formal requirements. Moreover, despite the existence of available abundant documentation on the Piast burials, the actual situation is not always consistent with the written sources. Our first experiences show how difficult it is to localize the remains, identify them and extract DNA of sufficient quality.
Źródło:
Opolskie Studia Administracyjno-Prawne; 2016, 14, 4 (2); 63-77
2658-1922
Pojawia się w:
Opolskie Studia Administracyjno-Prawne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
MELAS as an example of a mitochondrial disease
Autorzy:
Piechota, J
Mroczek, K.
Bartnik, E.
Powiązania:
https://bibliotekanauki.pl/articles/2041823.pdf
Data publikacji:
2001
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
encephalopathia
pathogenesis
mitochondrial DNA
genetics
tRNA gene
mitochondrial disease
mutation
mitochondrial myopathy
Źródło:
Journal of Applied Genetics; 2001, 42, 3; 351-358
1234-1983
Pojawia się w:
Journal of Applied Genetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Influence of plasmogenes on the productivity of morphogenesis in strawberry (Fragaria x ananassa Duch.)
Wpływ plazmogenów na produktywność morfogenezy u truskawki (Fragaria x ananassa Duch.)
Autorzy:
Zebrowska, J.
Pacek, A.
Powiązania:
https://bibliotekanauki.pl/articles/28140.pdf
Data publikacji:
2008
Wydawca:
Polskie Towarzystwo Botaniczne
Tematy:
plasmagene
productivity
morphogenesis
strawberry
Fragaria x ananassa
chloroplast DNA
inheritance
mitochondrial DNA
Opis:
Plasmogenes are largely located in mitochondria or plastids and they can infl uence the inheritance of many plant characteristics. This phenomenon is called cytoplasmic inheritance and can be detected on the basis of the expression of a trait in progeny F1 obtained from single and reciprocal crosses. The aim of this study was to examine the cytoplasmic inheritance of in vitro productivity of morphogenesis in three genotypes of Fragaria x ananassa Duch., i.e. the cultivars ‘Dukat’, ‘Teresa’ and the breeding clone no. 590. Single and reciprocal crosses were done according to Griffi ng’s method 3. The value of general combining ability (GCA) indicated cv. ‘Teresa’ as the best maternal component for crossing and ‘Dukat’ as the worst. The negative reciprocal cross effects (rij) revealed the cytoplasmic inheritance for cv. ‘Dukat’ as maternal form and positive rij for the breeding clone no. 590 indicated the nuclear inheritance of morphogenetic ability. Cv. ‘Teresa’, as maternal component, showed nuclear inheritance of that trait in crossing with cv. ‘Dukat’ and with 590 cytoplasmic inheritance. The productivity of morphogenesis in strawberry depended on the parental combination and the direction of crossing.
Plazmogeny zlokalizowane są głównie w mitochondriach oraz plastydach i mogą wpływać na dziedziczenie wielu cech u roślin. Zjawisko to określa się mianem dziedziczenia cytoplazmatycznego, wykrywanego na podstawie ekspresji danej cechy w pokoleniu F1, uzyskanym z krzyżowań prostych i odwrotnych. Celem badań było określenie wpływu dziedziczenia cytoplazmatycznego na produktywność morfogenezy in vitro trzech genotypów Fragaria x ananasa Duch. tj. odmiany ‘Dukat’, ‘Teresa’ i klonu hodowlanego nr 590. Proste i odwrotne krzyżowania wykonano według trzeciej metody Griffi ng’a. Najlepszym komponentem matecznym określonym na podstawie ogólnej zdolności kombinacyjnej (GCA) była odmiana ‘Teresa’, natomiast najsłabszym odmiana ‘Dukat’. Negatywny efekt krzyżowań odwrotnych (rij) wskazał na cytoplazmatyczne dziedziczenie zdolności morfogenetycznych u odmiany ‘Dukat’ jako formy matecznej, natomiast pozytywny rij na dziedziczenie jądrowe u klonu hodowlanego nr 590. U odmiany ‘Teresa’ jako komponentu matecznego, w krzyżowaniu z odmianą ‘Dukat’, stwierdzono dziedziczenie jądrowe danej cechy a cytoplazmatyczne w krzyżowaniu z klonem hodowlanym nr 590. Produktywność morfogenezy badanych odmian i klonu truskawki zależała od kombinacji rodzicielskiej oraz kierunku krzyżowania.
Źródło:
Acta Agrobotanica; 2008, 61, 2
0065-0951
2300-357X
Pojawia się w:
Acta Agrobotanica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Molekularna identyfikacja gatunków z rodzaju Abies na podstawie polimorfizmu DNA mitochondrialnego
Molecular identification of species from Abies genus based on the mitochondrial DNA polymorphism
Autorzy:
Pawlaczyk, E.M.
Staniak, J.
Maliński, T.
Bobowicz, M.A.
Powiązania:
https://bibliotekanauki.pl/articles/989708.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Leśne
Tematy:
lesnictwo
drzewa lesne
genetyka roslin
jodla
Abies
gatunki roslin
identyfikacja
haplotypy
DNA mitochondrialny
polimorfizm DNA
abies species
haplotype
capillary electrophoresis
mitochondrial marker
Opis:
The plant material was collected on 34 individuals growing in the Dendrological Garden of Poznań University of Life Sciences (52°25'32,95" N 16°53'39,83" E) and Botanical Garden of Adam Mickiewicz University in Poznań (52°25'11,70" N 16°52'55,07" E). The species for this study originated from Europe, Asia Minor, central and eastern Asia and North America and included: Abies alba, Abies cephalonica, Abies cilicica, Abies equi−trojani, Abies sibirica, Abies koreana, Abies pinsapo, Abies ×insignis, Abies bornmulleriana, Abies homolepsis, Abies holophylla, Abies grandis, Abies concolor, Abies concolor var. violacea, Abies concolor var. lowiana, Abies nordmanniana, Abies ×arnoldiana, Abies nephrolepis and Abies balsamea. The aim of this study was to define the species haplotypes (the length of allele) on the basis of nad5−4 mitochondrial DNA marker detected by capillary electrophoresis. This marker has been suggested as an easy−to−use tool to distinguish species of the Abies genus and it could be species−specific. Seven different haplotypes were identified. The first one appears in the species from Europe, Asia and North America. The second one was detected in firs from Europe and Asia Minor. A. cephalonica and A. sibirica were identified by the third haplotype, which occurs also in A. alba from the Balkan region. The fourth haplotype is characteristic for species from Asia and North America. The fifth and sixth haplotypes were identified in A. pinsapo and A. numidica. The seventh haplotype was detected only in A. holophylla. Applied marker is a very useful for verification of fir species especially allopatric species, less for parapatric ones. This marker is more helpful to exclude the species than to precisely identify them.
Źródło:
Sylwan; 2015, 159, 08; 675-683
0039-7660
Pojawia się w:
Sylwan
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Participation of non-coding RNAs in plant organelle biogenesis
Autorzy:
Rurek, Michal
Powiązania:
https://bibliotekanauki.pl/articles/1038718.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
non-coding RNAs
chloroplast DNA
mitochondrial DNA
organelle gene expression
stress response
Opis:
The biogenesis of plant mitochondria and plastids is a multistep process that depends on the expression of both, organellar and nuclear genes. A growing body of evidence suggests that the indispensable coordination of different steps in this process may be gained by participation of the non-coding RNAs. A plethora of non-coding RNAs of diverse length, both intraorganellar ones, as well as encoded by the nuclear genome (including microRNAs and short interfering RNAs), were also suggested to play a role in the stress response by regulating the expression levels of targeted genes important for organelle biogenesis. Selected points of current interest regarding the regulation of plant mitochondrial and plastid gene expression by diverse non-coding RNAs, also discussed in the aspect of abiotic stress conditions, are highlighted here.
Źródło:
Acta Biochimica Polonica; 2016, 63, 4; 653-663
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Characteristics of mitochondrial DNA of unionid bivalves (Mollusca: Bivalvia: Unionidae). II. Comparison of complete sequences of maternally inherited mitochondrial genomes of Sinanodonta woodiana and Unio pictorum
Autorzy:
Soroka, M.
Powiązania:
https://bibliotekanauki.pl/articles/84135.pdf
Data publikacji:
2010
Wydawca:
Uniwersytet Mikołaja Kopernika. Wydział Biologii i Ochrony Środowiska. Stowarzyszenie Malakologów Polskich
Opis:
The objective of the study was to sequence the complete female mitochondrial genomes of Sinanodonta woodiana and Unio pictorum, and toascertain their intra- and inter-specific variation within all the genes and non-coding regions. Complete sequence of maternally inherited mitochondrial genome of Sinanodonta woodiana is 16,243 bp long and is one of the three longest mt genomes in unionids; mt genome of Unio pictorum with its 15,761 bp is one of the smallest in the family. Each genome includes 14 protein-coding genes (13 as in most Metazoa, plus one open reading frame F ORF), 2 ribosomal RNA genes and 22 genes for transfer RNA with typical secondary structures, except for tRNA for serine1. S. woodiana has 25, and U. pictorum 27 non-coding sequences, which constitute 7.8 and 4.9% of mt genome, respectively. The content of A+T bases is 65.8% in S. woodiana and 65.1% in U. pictorum; the difference between the twospecies is 21%. Intra-specific variation in S. woodiana is three times greater than in U. pictorum. Lower nucleotide diversity within the second species suggests a small effective population size of the Polish U. pictorum. The twospecies show a similar usage of the most frequent and least frequent codons; the differences pertain to the usage of both stop codons. Gene trnS1 (serine, UGA) in unionids is very little variable with respect to tRNA secondary structure (absence of DHU arm), and nucleotide composition, while its inter-specific variation is half lower than in other mt-tRNAs.
Źródło:
Folia Malacologica; 2010, 18, 4
1506-7629
Pojawia się w:
Folia Malacologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
News of Pseudamnicola (Corrosella) of Spain and France (Mollusca: Gastropoda: Truncatelloidea)
Autorzy:
Boeters, H.D.
Callot-Girardi, H.
Knebelsberger, T.
Powiązania:
https://bibliotekanauki.pl/articles/83269.pdf
Data publikacji:
2015
Wydawca:
Uniwersytet Mikołaja Kopernika. Wydział Biologii i Ochrony Środowiska. Stowarzyszenie Malakologów Polskich
Tematy:
new species
Pseudamnicola
Corrosella
Spain
France
Mollusca
Gastropoda
Truncatelloidea
mitochondrial DNA
distribution range
Źródło:
Folia Malacologica; 2015, 23, 2
1506-7629
Pojawia się w:
Folia Malacologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Adaptor-mediated amplification of minute amounts of severely fragmented ancient nucleic acids
Autorzy:
Pusch, C M
Blin, N.
Broghammer, M.
Nicholson, G.J.
Scholz, M.
Powiązania:
https://bibliotekanauki.pl/articles/2042022.pdf
Data publikacji:
2001
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
mitochondrial DNA
genetics
nucleic acid
ancient DNA
polymerase chain reaction
DNA
cDNA
sex typing
Źródło:
Journal of Applied Genetics; 2000, 41, 4; 303-315
1234-1983
Pojawia się w:
Journal of Applied Genetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sirt3 regulates the level of mitochondrial DNA repair activity through deacetylation of NEIL1, NEIL2, OGG1, MUTYH, APE1 and LIG3 in colorectal cancer
Autorzy:
Kabziński, Jacek
Walczak, Anna
Mik, Michał
Majsterek, Ireneusz
Powiązania:
https://bibliotekanauki.pl/articles/1391859.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
cancer
colorectal cancer
DNA damage/repair
genetics
proteins
Opis:
Colorectal cancer (CRC) is one of the most common malignant tumors. One of the factors increasing the risk of its occurrence may be the reduced efficiency of repairing DNA damage, both nuclear and mitochondrial. The main mechanism for repairing oxidative damage is the BER system (in mitochondria mtBER), whose key proteins NEIL1, NEIL2, OGG1, MUTYH, APE1 and LIG3 obtain full efficiency only at the appropriate level of acetylation. Sirtuin 3 is a key protein for mitochondrial homeostasis, regulating a number of metabolic processes related mainly to the control of the level of reactive oxygen species. Because Sirt3 possesses acetylase activity, it can modulate the level of activity of mtBER proteins by their deacetylation. The conducted study showed that the tested proteins NEIL1, NEIL2, OGG1, MUTYH, APE1 and LIG3 are the substrate for the enzymatic deacetylation activity of Sirt3, which may lead to modulation of the risk of CRC, and in cancer cells may be a potential therapeutic target enhancing the action of cytostatic drugs.
Źródło:
Polish Journal of Surgery; 2020, 92, 1; 1-4
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Postglacjalna migracja jodły pospolitej (Abies alba Mill.) do Polski - analiza na podstawie polimorfizmu mitochondrialnego DNA
Postglacial migration of silver fir (Abies alba Mill.) to Poland - analysis on the basis of mitochondrial DNA polymorphism
Autorzy:
Pawlaczyk, E. M.
Kroplewska, I.
Bobowicz, M. A.
Powiązania:
https://bibliotekanauki.pl/articles/991708.pdf
Data publikacji:
2013
Wydawca:
Polskie Towarzystwo Leśne
Tematy:
drzewa lesne
migracje roslin
okres polodowcowy
Polska
jodla pospolita
Picea abies
populacje roslin
badania molekularne
DNA mitochondrialny
polimorfizm DNA
silver fir (abies alba mill.)
refugium
postglacial migration
mitochondrial marker
Opis:
Mitochondrial DNA marker was applied to 10 populations of silver fir from Poland and one from Belarusia. These populations were located within and beyond the natural range of silver fir. The marker exhibited two highly conserved alleles (first – 230 bp and second – 150 bp) based on an insertion−deletion of 80 bp in the fourth intron of the mitochondrial nad5 gene. The geographical distribution of the maternally inherited mitochondrial variation is known to support the existence of at least two refugia with two recolonizing maternal lineages remaining largely separated throughout the range. Our results provide that in all studied populations the first allele was discovered. Therefore we postulate that the silver fir migrate to Poland from the refugium in western Europe (probably from central Italy).
Źródło:
Sylwan; 2013, 157, 06; 458-463
0039-7660
Pojawia się w:
Sylwan
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Przypadek cytopatii mitochondrialnej
Mitochondrial cytopathy – case report
Autorzy:
Wieremiejczyk, Joanna
Adamkiewicz, Bożena
Sztamska, Elżbieta
Sikorska, Beata
Liberski, Paweł P.
Klimek, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1059233.pdf
Data publikacji:
2008
Wydawca:
Medical Communications
Tematy:
cytopatia mitochondrialna
mitochondrial DNA
mitochondrial cytopathy
mitochondrial diseases diagnosis
muscle biopsy
phenotype diversity
diagnostyka zaburzeń mitochondrialnych
biopsja mięśnia
różnorodność fenotypowa
mitochondrialne DNA
Opis:
Mitochondrial cytopathies are heterogeneous group witch may be caused by mutations in the mitochondrial as well as nuclear DNA. The most frequent type of inheritance is the maternal type. Difficulties with establishment type off inheritance are caused either by heterogeneous phenotype among family members or by de novo mutations. The phenotype diversity is defined by heteroplasmy and by limitary effect. Heteroplasmy (coexistence of wild-type and mutated DNA) may occur on cellular or on mitochondrial level. The grade of heteroplasmy may change in particular cells and tissues. We presented a case of 45-year-old man with multifocal brain lesion, cardiomyopathy with atrioventricular heart block with implanted cardiostimulator and epilepsy. Since patient was 20 year old he have had headache and incidents of transient blindness. In spite of implanting cardiostimulator losses of consciousness had returned. The epilepsy was diagnosed and treatment was initiated. In neurological examination we noticed multifocal symptoms. Patient was treated in many departments, where SM was suspected (based on MRI findings). Our diagnose was based on absence of clinical data for SM, multisystemic manifestations and issue of anatomopathological muscle biopsy.
Cytopatie mitochondrialne stanowią heterogenną grupę chorób wynikających z uszkodzenia zarówno mitochondrialnego (mtDNA), jak i jądrowego DNA. Najczęstszym typem dziedziczenia jest typ matczyny. Trudności w ustaleniu typu dziedziczenia mogą wynikać z różnorodności klinicznej ekspresji wśród członków rodziny oraz mutacji de novo. Różnorodność fenotypowa uwarunkowana jest heteroplazmią oraz tzw. efektem progowym. Heteroplazmia (współistnienie prawidłowego i zmutowanego mtDNA) może występować na poziomie komórki lub na poziomie poszczególnych mitochondriów. Stopień heteroplazmii zmienia się w poszczególnych komórkach i tkankach. Autorzy przedstawiają przypadek 45-letniego mężczyzny z wieloogniskowym uszkodzeniem OUN, kardiomiopatią z blokiem A-V, po implantacji kardiostymulatora oraz pada - czką. Od 20. roku życia występowały u pacjenta migrenopodobne bóle głowy z incydentami obuocznego zaniewidzenia oraz utraty przytomności, które pierwotnie przypisywano kardiomiopatii i zaburzeniom w układzie bodźco-przewodzącym serca. Pomimo wszczepienia kardiostymulatora utraty przytomności nadal powtarzały się, rozpoznano padaczkę i rozpoczęto terapię. W międzyczasie na podstawie wyniku badania MRI rozpoznano stwardnienie rozsiane; rozpoczęto leczenie. Biorąc pod uwagę całość obrazu klinicznego, przeprowadzono diagnostykę w kierunku choroby mitochondrialnej. Wynik badania histopatologicznego wycinka mięśniowego potwierdził nasze przypuszczenie.
Źródło:
Aktualności Neurologiczne; 2008, 8, 2; 109-114
1641-9227
2451-0696
Pojawia się w:
Aktualności Neurologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Frequent D-loop polymorphism in mtDNA enables genotyping of 1400-year-old human remains from Merowingian graves
Autorzy:
Zeller, M
Mirghomizadeh, F.
Wehner, H.D.
Blin, N.
Powiązania:
https://bibliotekanauki.pl/articles/2042042.pdf
Data publikacji:
2000
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
X chromosome
ancient remains
amplification technique
Y chromosome
ancient DNA
mtDNA
remains
Merowingian culture
polymorphism
mitochondrial DNA
man
DNA marker
DNA extraction
DNA
Źródło:
Journal of Applied Genetics; 2000, 41, 4; 285-292
1234-1983
Pojawia się w:
Journal of Applied Genetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mitochondrial and nuclear DNA differentiation of Picea abies populations in Poland
Autorzy:
Nowakowska, J A
Powiązania:
https://bibliotekanauki.pl/articles/40976.pdf
Data publikacji:
2009
Wydawca:
Polska Akademia Nauk. Instytut Dendrologii PAN
Tematy:
international conference
Europe
forest ecosystem
plant breeding
tree
Norway spruce
Picea abies
Polska
mitochondrial DNA
nuclear DNA
plant population
microsatellite marker
post-glacial migration
Opis:
The natural stands of Norway spruce in Poland are split between the southern and the northeastern parts of the country. Two so-called "spruceless" zones separate the northern spruce locations from those in the south, one "spruceless" zone is situated in Central Poland, and the other one in the Beskid Mts. Mitochondrial (STS) and nuclear (SSR) markers were used to perform the genetic identification of Norway spruce. Four different variants of haplotypes, "a", "b", "c" and "d", were found to occur in the nad1 locus of STS markers. Populations from the northern range of Picea abies distribution in Poland harboured exclusively haplotypes "c" and "d", except for the Białowieża population which had haplotypes "a" and "c". Populations from the "spruceless" zones contained four types of haplotypes whilst those from southern Poland were mostly composed of haplotype "a". High mean gene diversity was observed for both STS and SSR markers (HT = 0.529, and HT = 0.851, respectively). The total genetic differentiation of Norway spruce populations was very low (FST= 0.088). Two main groups of populations were distinguished in the dendrogram defined by Nei's genetic distances based on microsatellite markers. The distribution of the genotypes was scattered and did not show any connection with the spatial distribution of P. abies in Poland. Only the mtDNA markers were able to differentiate the northern populations of Norway spruce from the southern ones, proving the historical separation between the Baltico-Nordic and the Hercyno-Carpathian ranges of P. abies in Poland. By contrast, the microsatellite data suggested an overlap between the genotypes due to the human manipulation of Norway spruce stands in the past.
Źródło:
Dendrobiology; 2009, 61 Supplement
1641-1307
Pojawia się w:
Dendrobiology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Geographical pattern of haplotypic variation in Austrian native stands of Picea abies
Autorzy:
Mengl, M
Geburek, T.
Schueler, S.
Powiązania:
https://bibliotekanauki.pl/articles/41567.pdf
Data publikacji:
2009
Wydawca:
Polska Akademia Nauk. Instytut Dendrologii PAN
Tematy:
international conference
Europe
forest ecosystem
plant breeding
tree
Norway spruce
Picea abies
mitochondrial DNA
biogeography
genetic diversity
haplotypic variation
native stand
Austria
tree species
Opis:
In the present study we analysed the mitochondrial intraspecific variation in natural populations of Norway spruce. We used the second intron of the nad1 gene, which contains two polymorphic short tandem repeats. Due to the maternal inheritance of mitochondrial DNA in Norway spruce, the spatial distribution of haplotype DNA allows insights into seed dispersal and artificial seed transfer. A total of 504 trees distributed all over Austria were genotyped, and 9 different haplotypes could be found. A geographical map of the haplotype variation pattern of Picea abies is presented.
Źródło:
Dendrobiology; 2009, 61 Supplement
1641-1307
Pojawia się w:
Dendrobiology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pochodzenie drzewostanów świerkowych (Picea abies L. Karst.) z Puszczy Białowieskiej na tle regionu RDLP Białystok na podstawie analiz mitochondrialnego DNA
Origin of the Norway spruce (Picea abies L. Karst.) stands from Bialowieza Forest at the level of Bialystok Regional Directorate of the State Forests based on mitochondrial DNA analysis
Autorzy:
Nowakowska, J.A.
Łukaszewicz, J.
Borys, M.
Tereba, A.
Konecka, A.
Zawadzka, A.
Sułkowska, M.
Zajączkowski, P.
Powiązania:
https://bibliotekanauki.pl/articles/987121.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Leśne
Tematy:
lesnictwo
Puszcza Bialowieska
drzewostany swierkowe
drzewa lesne
swierk pospolity
Picea abies
markery genetyczne
DNA mitochondrialny
pochodzenie roslin
zmiennosc genetyczna
RDLP Bialystok
genetic diversity
mitochondrial dna marker
postglacial migration routes
białowieża forest
Opis:
Considered to be the most natural of all other Polish stands Picea abies in Białowieża Forest has suffered severely of bark beetle damages for decades. In order to find out some historical events in native Norway spruce stands diversity at regional level, we carried out the study on poly− morphism with DNA markers and performed Principal Coordinate Analysis (PCoA) on the basis of genetic distance matrix. Two ranges (i.e. Baltico−Nordic and Hercyno−Carpathian) of Norway spruce cover north−eastern and southern Poland, respectively. The spruceless zone separates the these two ranges in lowland Poland. From genetic point of view, the Baltico−Nordic P. abies populations mainly harbor mitochondrial haplotype ‘c', whereas the spruces from the Hercyno− −Carpathian range – haplotype ‘a'. Until recently, the Białowieża Forest has been considered to belong to the northern range of spruce occurrence in Europe. Seven populations from Biało− wieża Forest were studied (two of them from the Strict Reserve in Białowieski National Park) according to mitochondrial DNA diversity, and compared with genetic diversity found in 24 other populations located in Białystok Regional Directorate of the State Forests (north−eastern Poland). All studied spruce populations were more than 100 years old and were of natural origin. As result, the spruces from the Białowieża Forest harbored three mitochondrial haplotypes of the nad1 gene (‘c', ‘a' and ‘a1'), with the haplotype ‘a' being more frequently present (>51%) than the hap− lotype ‘c'. The spruce stands from Białowieża Forest have the highest gene diversity (h Nei=0.527) comparing to the other stands from the Białystok RDSF. The PCoA proved the particularity of the spruces from Białowieża Forest grouping them into one cluster of genetic similarity. Our data demonstrated that most of Norway spruces populations from Białystok RDSF harbor haplotype ‘c', which confirms their historical relationship with the Baltico−Nordic range of P. abies in Europe, while most spruces from Białowieża Forest have different historic origin, because they share high frequency of the southern haplotype ‘a'. It also turned out that Norway spruce pop− ulations from two different European ranges met in lowland Poland after the last glacial period, as proved by the presence of two mitochondrial haplotypes ‘a' and ‘c'. It can be assumed, that the spruceless zone was created by human activity in the past millennia. The results of all molecular analyses confirmed the unique character of spruces of Białowieża Forest, which is distinguished by the greater richness of the gene pool in comparison to the region of Białystok RDSF as well as good adaptation to local environmental conditions.
Źródło:
Sylwan; 2017, 161, 01; 40-51
0039-7660
Pojawia się w:
Sylwan
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Historia biologiczna populacji Homo sapiens zamieszkujących centralną i wschodnią części Europy
Biological history of Homo sapiens populations living in Central and Eastern Europe
Autorzy:
Marcinkowska-Swojak, Małgorzata
Stolarek, Ireneusz
Zeńczak, Michał
Handschuh, Luiza
Figlerowicz, Marek
Powiązania:
https://bibliotekanauki.pl/articles/2197849.pdf
Data publikacji:
2023-03-31
Wydawca:
Wydawnictwo Adam Marszałek
Tematy:
historia biologiczna
Homo sapiens
archeogenomika
sekwencjonowanie nowej generacji
kopalny DNA (aDNA)
haplogrupy mitochondrialnego DNA
haplogrupy chromosomu Y
biological history
archaeogenomics
next-generation sequencing
ancient DNA (aDNA)
mitochondrial DNA haplogroups
Y-chromosome haplogroups
Opis:
Archaeogenomis is a recently developed interdisciplinary research field that utilizes advanced molecular biology techniques, especially DNA sequencing, to study the history of biological species, including humans. Analyses of ancient genomes provide independent information about human ancestors and their migrations, allowing researchers to uncover history of mankind. Here, we present the fundamental principles of archaeogenomics and its application in the studies of biological history of the populations inhabiting central-east Europe.
Źródło:
Historia Slavorum Occidentis; 2023, 1(36); 143-165
2084-1213
Pojawia się w:
Historia Slavorum Occidentis
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Broad Taxon Sampling of Ciliates Using Mitochondrial Small Subunit Ribosomal DNA
Autorzy:
DUNTHORN, Micah
HALL, Meaghan
Foissner, Wilhelm
STOECK, Thorsten
KATZ, Laura A.
Powiązania:
https://bibliotekanauki.pl/articles/763463.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego
Tematy:
Ciliophora, Colpodea, mitochondria, phylogeny, Phyllopharyngea, SSU-rDNA
Opis:
Mitochondrial SSU-rDNA has been used recently to infer phylogenetic relationships among a few ciliates. Here, this locus is compared with nuclear SSU-rDNA for uncovering the deepest nodes in the ciliate tree of life using broad taxon sampling. Nuclear and mitochondrial SSU-rDNA reveal the same relationships for nodes well-supported in previously-published nuclear SSU-rDNA studies, although support for many nodes in the mitochondrial SSU-rDNA tree are low. Mitochondrial SSU-rDNA infers a monophyletic Colpodea with high node support only from Bayesian inference, and in the concatenated tree (nuclear plus mitochondrial SSU-rDNA) monophyly of the Colpodea is supported with moderate to high node support from maximum likelihood and Bayesian inference. In the monophyletic Phyllopharyngea, the Suctoria is inferred to be sister to the Cyrtophora in the mitochondrial, nuclear, and concatenated SSU-rDNA trees with moderate to high node support from maximum likelihood and Bayesian inference. Together these data point to the power of adding mitochondrial SSU-rDNA as a standard locus for ciliate molecular phylogenetic inferences.
Źródło:
Acta Protozoologica; 2014, 53, 2
1689-0027
Pojawia się w:
Acta Protozoologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pochodzenie świerka pospolitego (Picea abies (L.) Karst.) w Nadleśnictwie Kartuzy
Origin of Norway spruce (Picea abies (L.) Karst.) in the Kartuzy Forest District
Autorzy:
Lewandowski, A.
Szydlarski, M.
Litkowiec, M.
Powiązania:
https://bibliotekanauki.pl/articles/989990.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Leśne
Tematy:
lesnictwo
Nadlesnictwo Kartuzy
drzewa lesne
swierk pospolity
Picea abies
pochodzenie roslin
badania genetyczne
markery genetyczne
DNA mitochondrialny
origin
picea abies
mitochondrial marker
mitotype
Opis:
The origin of the Norway spruce in the Kartuzy Forest District was verified using the maternally inherited mitochondrial DNA marker mt15−D02 that shows distinct geographical distribution in Europe. We analyzed 462 trees from 26 populations. The majority of trees were of Alpine origin and they were present in all populations at a frequency of 6−90% (mean 59%). About 30% of trees were of the Carpathian origin and the least abundant (11%) were trees of north−eastern origin. The trees carrying north−eastern type of the mitochondial DNA marker were found only in 13 populations, but at a very different frequency (from 5 to 88%). The possibility of natural origin of Norway spruce in the area of Kartuzy Forest District was shortly discussed.
Źródło:
Sylwan; 2014, 158, 07; 509-515
0039-7660
Pojawia się w:
Sylwan
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mutations in DNA polymerase gamma cause error prone DNA synthesis in human mitochondrial disorders
Autorzy:
Copeland, William
Ponamarev, Mikhail
Nguyen, Dinh
Kunkel, Thomas
Longley, Matthew
Powiązania:
https://bibliotekanauki.pl/articles/1043659.pdf
Data publikacji:
2003
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
aging
DNA replication
mitochondria
DNA repair
DNA polymerase
Opis:
This paper summarizes recent advances in understanding the links between the cell's ability to maintain integrity of its mitochondrial genome and mitochondrial genetic diseases. Human mitochondrial DNA is replicated by the two-subunit DNA polymerase γ (pol γ). We investigated the fidelity of DNA replication by pol γ with and without exonucleolytic proofreading and its p55 accessory subunit. Pol γ has high base substitution fidelity due to efficient base selection and exonucleolytic proofreading, but low frameshift fidelity when copying homopolymeric sequences longer than four nucleotides. Progressive external ophthalmoplegia (PEO) is a rare disease characterized by the accumulation of large deletions in mitochondrial DNA. Recently, several mutations in the polymerase and exonuclease domains of the human pol γ have been shown to be associated with PEO. We are analyzing the effect of these mutations on the human pol γ enzyme. In particular, three autosomal dominant mutations alter amino acids located within polymerase motif B of pol γ. These residues are highly conserved among family A DNA polymerases, which include T7 DNA polymerase and E. coli pol I. These PEO mutations have been generated in pol γ to analyze their effects on overall polymerase function as well as the effects on the fidelity of DNA synthesis. One mutation in particular, Y955C, was found in several families throughout Europe, including one Belgian family and five unrelated Italian families. The Y955C mutant pol γ retains a wild-type catalytic rate but suffers a 45-fold decrease in apparent binding affinity for the incoming dNTP. The Y955C derivative is also much less accurate than is wild-type pol γ, with error rates for certain mismatches elevated by 10- to 100-fold. The error prone DNA synthesis observed for the Y955C pol γ is consistent with the accumulation of mtDNA mutations in patients with PEO. The effects of other pol γ mutations associated with PEO are discussed.
Źródło:
Acta Biochimica Polonica; 2003, 50, 1; 155-167
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Complete mitochondrial genome of wild aurochs (Bos primigenius) reconstructed from ancient DNA
Autorzy:
Zeyland, J.
Wolko, L.
Bocianowski, J.
Szalata, M.
Slomski, R.
Dzieduszycki, A.M.
Ryba, M.
Przystalowska, H.
Lipinski, D.
Powiązania:
https://bibliotekanauki.pl/articles/31815.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
Extinct aurochs (Bos primigenius), accepted as the ancestor of domestic cattle, was one of the largest wild animals inhabiting Europe, Asia and North Africa. The gradual process of aurochs extinction finished in Poland in 1627, were the last recorded aurochs, a female, died. Some aspects of cattle domestication history and the distribution of aurochs genetic material among modern cattle breeds still remain unclear. Analyses of ancient DNA (aDNA) from bone sample deliver new genetic information about extinct wild aurochs as well as modern cattle phylogeny. DNA was extracted from a fragment of aurochs fossil bone found in the Pisz Forest, Poland. The sample was radiocarbon-dated to about 1500 yBP. The aDNA was used for Whole Genome Amplification in order to form a DNA bank. Auroch mitochondrial DNA sequences were amplified using sets of 41 primers overlapping the whole mtDNA, cloned and sequenced. The sequence of the whole mitochondrial genome was reconstructed and deposed in GenBank [GenBank:JQ437479]. Based on the phylogenetic analyses of the Bovine mitochondrial genomes, a phylogenetic tree was created. As expected, the tree clearly shows that the mtDNA sequence of the analyzed PWA (Polish Wild Aurochs) individual belongs to haplogroup P. In the course of the comparative mtDNA analysis we identified 30 nucleotide marker positions for haplogroup P and nine unique PWA differences compared to the two remaining haplotype P representatives. Our analysis provides the next step to the reconstruction of the demographic history of this extinct but still exciting species.
Źródło:
Polish Journal of Veterinary Sciences; 2013, 16, 2
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mitochondrial transcription factor A is the major protein in rodent hepatocytes that recognizes DNA lesions induced by N-acetoxy-acetylaminofluorene
Autorzy:
Pietrowska, Monika
Kołodziejczyk, Izabela
Widłak, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/1041174.pdf
Data publikacji:
2006
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
UV-radiation
cisplatin
TFAM
AAAF
Opis:
Extracts from rodent liver cells contain an abundant protein that recognizes DNA adducts induced by the chemical carcinogen N-acetoxy-acetylaminofluorene (AAAF). This protein also has a strong affinity for DNA damaged by cisplatin (DDP), but not by benzo(a)pyrene diolepoxide or UV-radiation, and has been termed AAAF/DDP-DDB. Here we purified this protein from rat tissue and analyzed it by mass spectrometry and identified it as mitochondrial transcription factor A (TFAM). Experiments with bacterially expressed recombinant TFAM confirmed its high affinity for DNA damaged by AAAF. Assuming its abundance and specificity for AAAF induced lesions, TFAM may significantly impede recognition and repair of DNA adducts induced by AAAF and other derivatives of 2-aminofluorene.
Źródło:
Acta Biochimica Polonica; 2006, 53, 4; 777-782
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Application of molecular techniques to taxonomic studies
Autorzy:
Lesicki, A.
Szweykowska-Kulinska, Z.
Powiązania:
https://bibliotekanauki.pl/articles/84088.pdf
Data publikacji:
1999
Wydawca:
Uniwersytet Mikołaja Kopernika. Wydział Biologii i Ochrony Środowiska. Stowarzyszenie Malakologów Polskich
Tematy:
application
molecular technique
taxonomy
genome organization
phylogenetic analysis
rRNA gene
animal genome
mitochondrial genome
nuclear genome
DNA hybridization
mollusc
phylogenesis
Źródło:
Folia Malacologica; 1999, 07, 4
1506-7629
Pojawia się w:
Folia Malacologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Genetic studies on the invasive slug Arion lusitanicus Mabille, 1868 (Gastropoda: Pulmonata) in Poland
Autorzy:
Soroka, M.
Kaluski, T.
Powiązania:
https://bibliotekanauki.pl/articles/83651.pdf
Data publikacji:
2011
Wydawca:
Uniwersytet Mikołaja Kopernika. Wydział Biologii i Ochrony Środowiska. Stowarzyszenie Malakologów Polskich
Tematy:
animal genetics
invasive species
slug
Arion lusitanicus
pest
Gastropoda
Pulmonata
Polska
migration route
DNA
mitochondrial gene
Arionidae
cytochrome oxidase subunit 1 gene
Opis:
Within the last decades the slug Arion lusitanicus has expanded its range over wide areas of Europe, in most of them it is now a serious pest. Poland has been invaded relatively recently (since the late 1980s). Considering the ecological importance of the slug, very little is known yet about the mechanism of invasion, establishment of new populations and influence on the native fauna and flora. The analysis of nucleotide sequences of mitochondrial cytochrome oxidase subunit 1 gene (cox1) revealed a great inter- and intrapopulation variation in the Polish populations of A. lusitanicus. The differentiation of all the studied Polish populations of A. lusitanicus is 0.2–2.2%, while two analysed Belgian populations are monomorphic and moderately genetically diverse at 0.8%. This indicates a heterogeneous origin of the Polish populations, probably resulting from multiple independent introduction events. The genotype found in the first four Polish populations (S. Poland) suggests that their origin is different from the remaining populations.
Źródło:
Folia Malacologica; 2011, 19, 4
1506-7629
Pojawia się w:
Folia Malacologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Śladami badań Władysława Jedlińskiego – określenie pochodzenia świerka na terenie Nadleśnictwa Skrwilno
Following the research of Wladyslaw Jedlinski – determination of the origin of spruce in the Skrwilno Forest District
Autorzy:
Lewandowski, A.
Litkowiec, M.
Fischer, A.
Powiązania:
https://bibliotekanauki.pl/articles/1008413.pdf
Data publikacji:
2012
Wydawca:
Polskie Towarzystwo Leśne
Tematy:
lesnictwo
Nadlesnictwo Skrwilno
drzewa lesne
swierk pospolity
Picea abies
pochodzenie roslin
markery genetyczne
DNA mitochondrialny
origin
picea abies
mitochondrial marker
Opis:
Origin of Norway spruce in the territory of Skrwilno Forest District was studied with the use of mitochondrial mt−D02 region inherited through maternal line. The former suppositions of Jedliński, who claimed that the origin of spruce in this territory was natural, have been confirmed. Concurrently, it has been established that in the majority of tree stands subject to our study there occurs spruce of Carpathian origin. The obtained results together with the palinological data indicate that the northern border of spruce range in Poland runs right through the territory of Skrwilno Forest District and not about 100 km to the south from this place as has been claimed so far.
Źródło:
Sylwan; 2012, 156, 09; 703-709
0039-7660
Pojawia się w:
Sylwan
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Weryfikacja pochodzenia świerka pospolitego (Picea abies) w Nadleśnictwie Gołdap
Verification of the origin of Norway spruce (Picea abies) stands in the Goldap Forest District
Autorzy:
Lewandowski, A.
Litkowiec, M.
Grygier, A.
Dering, M.
Powiązania:
https://bibliotekanauki.pl/articles/972766.pdf
Data publikacji:
2012
Wydawca:
Polskie Towarzystwo Leśne
Tematy:
region mt-D02
lesnictwo
Nadlesnictwo Goldap
drzewa lesne
swierk pospolity
Picea abies
drzewa mateczne
pochodzenie roslin
weryfikacja
metody badan
markery genetyczne
DNA mitochondrialny
origin
mitochondrial marke
Opis:
The origin of the Norway spruce in the Gołdap Forest District from the north−eastern part of Poland was verified using the maternally inherited mitochondrial marker mt15−D02, which in Poland displays a geo−graphical specifity. We analyzed 730 trees from 29 populations and 21 plus trees. These populations included four reserves, four registered seed stand and 21 managed tree−stands. As a result of the performed analyses it was found that 8 out of 21 plus trees were non−native. Also 11 out of the 29 investigated pop−ulations contained trees of non−native origin. The scale of this phenomenon varies, although it encom−passes the entire region of the forest district.
Źródło:
Sylwan; 2012, 156, 07; 494-501
0039-7660
Pojawia się w:
Sylwan
Dostawca treści:
Biblioteka Nauki
Artykuł
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