- Tytuł:
- Effect of a high amino acid diet on antioxidant barrier parameters of rat skin.
- Autorzy:
-
Niczyporuk, M.
Knaś, M.
Grądzka, K.
Car, H. - Powiązania:
- https://bibliotekanauki.pl/articles/1918838.pdf
- Data publikacji:
- 2019
- Wydawca:
- Uniwersytet Medyczny w Białymstoku
- Tematy:
-
Whey protein concentrate
oxidative stress
skin
rat - Opis:
- Introduction: Oxidative stress is largely responsible for numerous skin complications that occur in the course of various diseases as well as accelerated skin aging. A high amino acid diet, supplemented with whey protein concentrate (WPC), is well-balanced and has well-absorbing proteins, which are an ideal source of essential amino acids. Purpose: To assess what changes will occur in the antioxidant barrier of unharmed skin of rats on a high amino acid diet. Materials and methods: The study was conducted on sexually mature male Wistar rats (160-180g): 1. control (standard feed), 2. high amino acid diet (WPC-80 80% whey protein) administered for 7 days at a dose of 0.3g/kg of body weight, 3. WPC-80 for 7 days at a dose of 0.5g/kg of body weight, 4. WPC-80 for 14 days at a dose of 0.3g/kg of body weight, 5. WPC-80 for 14 days at a dose of 0.5g/kg of body weight. Total antioxidant capacity, total oxidative status and oxidative stress index were determined. Results: Enrichment of a standard diet with WPC-80 did not affect the total oxidative status of undamaged healthy rat skin. This study shows that a diet rich in amino acids in rats caused an increase in total antioxidant capacity, but statistically significant values were obtained after 14 days of administering WPC at a dose of 0.5mg/kg of body weight. Conclusions: Enrichment of a standard diet with WPC-80 strengthens the antioxidant barrier in unwounded healthy rat skin.
- Źródło:
-
Progress in Health Sciences; 2019, 1; 45-50
2083-1617 - Pojawia się w:
- Progress in Health Sciences
- Dostawca treści:
- Biblioteka Nauki
Artykuł