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Tytuł:
Diagnostic value of cone beam computed tomography in complex and compound odontomas: a systematic review and open classification matrix
Autorzy:
Dubron, Kathia
Gurniak, Anna
Gurniak, Eliza
Politis, Constantinus
Olszewski, Raphael
Powiązania:
https://bibliotekanauki.pl/articles/2129084.pdf
Data publikacji:
2022-05-08
Wydawca:
Presses Universitaires de Louvain
Tematy:
cone beam computed tomography
CBCT
complex odontoma
compound odontoma
odontogenic tumours
Opis:
Objective: Firstly, this review aims to analyse the recent literature about three-dimensional (3D) diagnostic imaging in complex and compound odontomas and compare it to two-dimensional (2D) imaging. Panoramic radiographs help to evaluate the vertical position of odontomas, and occlusal radiographs are used to evaluate the proximity to adjacent teeth. However, cone beam computed tomography (CBCT) can offer volumetric images, and therefore, a more accurate three-dimensional analysis. Secondly, this research aims to construct an open classification matrix for complex and compound odontomas for dentomaxillofacial CBCT radiology protocols based on a systematic literature review. Material and methods: Two systematic literature searches were conducted in PubMed (Medline), on 2 February 2022 concerning classification systems, and on 5 February 2022 concerning CBCT images. Results: In total, these searches revealed 391 papers by reviewing the databases mentioned above. Six articles were selected for inclusion on classification of odontomas and 13 articles were found on CBCT imaging. Consequently, the construction of an open classification matrix for compound and complex odontomas for dentomaxillofacial CBCT radiology protocols was performed using these 19 articles. Conclusions: CBCT offers a more precise position and accurate diagnosis of complex and compound odontomas compared to 2D imaging. Consequently, it enhances the detailed view of the site (multiple or unique), location (intraosseous, partially or completely extragnathic), size, extension (bony expansion, thinning or perforation cortical bone), density and type (denticulo type, particle type, denticulo-particle type, denticulo-amorphous type, amorphous tissue), relationship (with the crown or root of the definitive tooth), adjacent teeth resorption (deciduous or definitive), adjacent teeth (retention or impaction), and distance with adjacent structures (inferior alveolar nerve, sinus maxillaris), as well as adequate surgical planning. Moreover, this research presents an open classification matrix for the most complete description of compound and complex odontomas when analysing CBCT imaging.  
Źródło:
Nemesis. Negative Effects in Medical Sciences Oral and Maxillofacial Surgery; 2022, 23, 1; 1-50
2593-3604
Pojawia się w:
Nemesis. Negative Effects in Medical Sciences Oral and Maxillofacial Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Plasma interleukin-1α and interleukin-8 in female dogs with non-metastatic and metastatic malignant mammary gland tumours
Autorzy:
Szczubiał, M.
Łopuszyński, W.
Dąbrowski, R.
Bochniarz, M.
Brodzki, P.
Powiązania:
https://bibliotekanauki.pl/articles/16539196.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
IL-1α
IL-8
canine mammary tumours
plasma
metastases
Opis:
In this study plasma concentrations of IL-1α and IL-8 in 29 female dogs with malignant mammary gland tumours (19 without metastasis and 10 with metastasis) and in 10 healthy control animals were determined. Concentrations of IL-1α and IL-8 were analysed using a specific canine ELISA assay. Mean plasma concentrations of IL-1α and IL-8 were significantly higher (p<0.05) in female dogs with both non-metastatic and metastatic malignant tumours compared to the healthy animals. The concentrations of both tested cytokines were significantly increased (p<0.05) in the dogs with metastasis. In female dogs with mammary carcinomas, the plasma concentration of IL-1α was significantly higher (p<0.05) in the animals with grade 3 tumours compared to the dogs with grade 1 tumours. The concentration of IL-8 was significantly higher (p<0.05) in the dogs with grade 3 tumours compared to that found in the animals with grade 1 and grade 2 tumours. A moderate correlation (r=0.433) was found between IL-1α and IL-8 concentrations in the female dogs. These findings suggest that increased malignancy and invasiveness of canine mammary tumours is associated with an increased production of IL-1α and IL-8 in the tumour microenvironment, which, in turn, leads to an increase in their circulating levels. This may indicate that circulating levels of the cytokines investigated could be considered as diagnostic and prognostic markers in canine malignant mammary tumours. However, further studies in this fields are needed.
Źródło:
Polish Journal of Veterinary Sciences; 2022, 25, 2; 317-324
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analiza wielkości guzów OUN jako weryfikacja efektów leczenia radiochirurgicznego nerwiaków techniką Gamma Knife – badanie pilotażowe
Analysis of the size of CNS tumours as a verification of the effects of radio surgical treatment of neuromas using the Gamma Knife technique – pilot study
Autorzy:
Antończyk-Szewczyk, Katarzyna
Szurko, Agnieszka
Wydmańska, Anna
Mitek, Anna
Stanek, Agata
Cholewka, Armand
Powiązania:
https://bibliotekanauki.pl/articles/2146797.pdf
Data publikacji:
2020
Wydawca:
Indygo Zahir Media
Tematy:
Gamma Nóż
nowotwór mózgu
nerwiak
izodoza terapeutyczna
izodoza 90%
Gamma Knife
brain tumours
neuroma
therapeutic isodose
isodose 90%
Opis:
Nowotwory ośrodkowego układu nerwowego (OUN) wywodzą się z mózgu, rdzenia, opon mózgowych, a także są efektem przerzutów z nowotworów powstałych w innych narządach. Nawet zmiany histologicznie niezłośliwe mogą powodować śmierć wskutek ucisku na życiowo ważne struktury [1]. Nowotwory mózgu powodują 3% zgonów nowotworowych u obu płci i 1/3 zgonów nowotworowych u dzieci (0-19 lat) [2]. Gamma Knife stosowany jest w radiochirurgii stereotaktycznej w celu leczenia nowotworów zlokalizowanych w obrębie głowy oraz szyi. Ta metoda leczenia polega na precyzyjnym dostarczeniu dawki promieniowania w obszar guza [3]. Napromieniowanie zwykle nie powoduje natychmiastowego zniszczenia komórki. Obecność przetrwałego guza w krótkim czasie po zakończeniu napromieniania nie musi oznaczać nieskuteczności terapii. Analiza obrazów guza wykonanych w każdej płaszczyźnie przed leczeniem i po radiochirurgii wykazała znaczny wzrost objętości guza w pierwszej obserwacji, po którym nastąpił istotny statystycznie spadek. Ponadto analiza otrzymanych obrazów uwzględniająca izodozę terapeutyczną (linia żółta) oraz izodozę 90% (linia zielona) umożliwiła precyzyjną obserwację efektów leczenia.
Tumours of the central nervous system (CNS) originate in the brain, spine, meninges, and are also the result of metastases from tumours in other organs. Even histologically benign changes may cause death as a result of pressure on vital structures [1]. Brain tumours cause 3% of cancer deaths in both sexes and 1/3 of deaths in children (0-19 years) [2]. Gamma Knife is used in stereotaxic radiosurgery to treat neoplasms located in the head and neck area. This method of treatment is based on a precise radiation dose delivery to the tumour area [3]. Irradiation does not usually destroy the cell immediately. The presence of a persistent tumour shortly after the end of irradiation does not necessarily mean that the therapy is ineffective. Analysis of tumour images taken in each plane before treatment and after radiosurgery showed a significant increase in tumour volume at the first follow-up, followed by a statistically significant decrease. Moreover, the analysis of the obtained images using the therapeutic isodose (yellow line) and the 90% isodose (green line), made it possible to precisely observe the effects of the treatment.
Źródło:
Inżynier i Fizyk Medyczny; 2020, 9, 6; 435--440
2300-1410
Pojawia się w:
Inżynier i Fizyk Medyczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hazards of electromagnetic radiation
Zagrożenia przez promieniowanie elektromagnetyczne
Autorzy:
Jeleński, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1831407.pdf
Data publikacji:
2020
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Technologii Materiałów Elektronicznych
Tematy:
electromagnetic field
high voltage power lines
mobile phone base stations
mobile phones
radio and TV transmitters
household appliances
leukaemia
brain tumours
pole elektromagnetyczne
linie wysokiego napięcia
stacje bazowe telefonii komórkowej
telefony komórkowe
nadajniki radiowe i TV
sprzęt AGD
białaczka
nowotwory mózgu
Opis:
After a brief overview of the nature of electromagnetic (EM) radiation and its sources, the article presents selected findings concerning the risks caused by low-frequency EM fields emitted by 50 Hz high-voltage power lines and home appliances. These sources of radiation affect mainly the nervous system and may contribute to the development of cancer. On the other hand, the impact of high frequency EM fields emitted by radio and television transmitters, and mobile phones originate mainly from dielectric losses leading to body heating (thermal hazards) as well as from some non-thermal hazards, which have been less extensively investigated. The remote consequences include: auditory and behavioural effects, blood-brain barrier disruption and cancer. The examples of the recommendations and standards developed by the international and national organizations are also presented.
Po krótkim omówieniu źródeł i charakteru promieniowania elektromagnetycznego przedstawiono wybrane wyniki badań zagrożeń powodowanych przez pola EM niskiej częstotliwości emitowane przez linie energetyczne wysokiego napięcia 50 Hz i sprzęt AGD. Ich głównym efektem jest oddziaływanie na układ nerwowy i wpływ na choroby nowotworowe. Z kolei efektem pól EM wysokich częstotliwości emitowanych przez nadajniki radiowe, telewizyjne, telefony komórkowe są głównie straty dielektryczne prowadzące do nagrzewania ciała (zagrożenia termiczne) oraz słabiej zbadane zagrożenia nietermiczne. Do tych ostatnich należą: efekty słuchowe, behawioralne, zakłócenia działania bariery krew-mózg, choroby nowotworowe. Przedstawiono również przykłady zaleceń i norm opracowanych przez międzynarodowe i krajowe organizacje.
Źródło:
Materiały Elektroniczne; 2020, T. 48, nr 1-4, 1-4; 3-14
0209-0058
Pojawia się w:
Materiały Elektroniczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Rare Benign cystic teratoma in the parotid gland
Autorzy:
Gharaibeh, Mahmoud M.
Wadiya, Ahmed Al
Gharaibeh, Ahmad
Hammad, Huda
Powiązania:
https://bibliotekanauki.pl/articles/454919.pdf
Data publikacji:
2020-03-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
benign cystic teratoma
parotid gland
benign parotid tumours
Opis:
Introduction. A teratoma is a tumor developed of several different types of tissue, like hair, muscle, teeth or bone. Aim. Mature benign cystic teratomas are very rare in the salivary glands and just few cases were reported. Description of the case. A 13 years old female was presented to our dental clinic of Princes Basma Hospital in Irbid in north of Jordan, with a painless, insidious progressive swelling in left parotid region without any significant family and personal history. Parents were cancer phobic and nervous from the condition of their daughter, they were very confused. There was no pain or any history of trauma. It was present just inferior to left ear cartilage. The mass was of size 3x3cm, non-tender, fixed, soft to firm in consistency, having smooth surface. Conclusion. Teratoma in parotid region is an extremely rare entity. Lack of any pathognomonic feature, it is hard to diagnose preoperatively. Lumpectomy is advisable to remove the mass because the risk of damaging facial nerve in young patients and recurrence is rare. A definitive diagnosis is achieved after the histopathological study. Teratoma should be kept in account while evaluating a case of a soft tissue mass of parotid gland as a differential diagnosis.
Źródło:
European Journal of Clinical and Experimental Medicine; 2020, 1; 42-44
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Complications of radio- and radiochemotherapy in patients undergoing major salivary gland cancer surgery
Autorzy:
Kordzińska-Cisek, Izabela
Grzybowska-Szatkowska, Ludmiła
Powiązania:
https://bibliotekanauki.pl/articles/1397794.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
salivary gland tumours
radiotherapy
radiochemotherapy
radiation-induced reaction
Opis:
Purpose: The aim of this retrospective study was to present the prevalence of early and late radiation-induced reaction and factors affecting its formation and severity in patients after adjuvant radio- or radiochemotherapy in salivary gland cancer. Material and methods: A total of 113 patients with early and 91 with late radiation-induced reaction, irradiated in 2006-2016 were enrolled in the study. The frequency of acute mucosal radiation-induced reaction, time of onset, intensity, healing time, as well as the incidence of late radiation-induced reaction from the skin and subcutaneous tissue were analyzed. Factors that could influence the development and intensity of reaction were identified. Results: Acute severity and the presence of late radiation-induced reaction do not affect overall survival. Dosage in the tumor bed site, as well as the dosage in the nodal region, affect the severity of the acute radiation-induced mucosal reaction. The severity of the early radiation-induced reaction is higher in men, more advanced patients (higher T and N+ in TNM classification), irradiated into a larger area, and those in whom two-dimensional planning and complementary chemoradiotherapy were applied. The late reaction of the skin and subcutaneous tissue was dominated by patients irradiated in the nodal regions and those with a higher intensity of early radiation-induced reaction. Conclusions: Supplementary radiotherapy or radiochemotherapy in salivary gland cancer is associated with acceptable toxicity which has no effect on overall survival.
Źródło:
Polish Journal of Otolaryngology; 2019, 73, 3; 26-31
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Challenges in diagnosing and treating pancreatic neuroendocrine tumours in patients with a multiple endocrine neoplasia type 1 (MEN1) syndrome
Autorzy:
Rogozik, Natalia
Kolasińska-Ćwikła, Agnieszka
Ćwikła, Jarosław B.
Cichocki, Andrzej
Przybyłkowski, Adam
Słodkowski, Maciej
Bednarczuk, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1035818.pdf
Data publikacji:
2018
Wydawca:
Medical Education
Tematy:
diagnosis
multiple endocrine neoplasia type 1 syndrome
pancreatic neuroendocrine tumours
treatment
Opis:
Multiple endocrine neoplasia type 1 (MEN1) syndrome is an autosomal dominant hereditary disorder characterised by coexistence of pancreatic neuroendocrine tumours (pNETs) with parathyroid and pituitary tumours. PNETs, including mostly non-functioning tumours, gastrinoma and insulinoma, occur in nearly 95% of MEN1 patients and account for over 50% of disorder-related mortality. Therefore, early initiation of screening for pNET using biochemical and imaging tests as well as appropriate surgical and systemic treatment are of particular importance for this group of patients. Currently, there are no clearly defined guidelines which determine the optimal methods for detection and treatment of pNET in MEN1. Caution should be exercised when applying the guidelines designed for patients with sporadic pNET to MEN1 patients as the clinical course of the disorder is slightly different, involving multifocality of lesions and younger age of patients at onset. This paper discusses the distinctive features and challenges in diagnosing and treating pNETs in MEN1 patients.
Źródło:
OncoReview; 2018, 8, 2; 42-47
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Changes in serum neopterin and C-reactive protein concentrations in female dogs with mammary gland tumours
Autorzy:
Szczubiał, M.
Dabrowski, R.
Łopuszyński, W.
Bochniarz, M.
Krawczyk, M.
Powiązania:
https://bibliotekanauki.pl/articles/2087616.pdf
Data publikacji:
2018
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
neopterin
C-reactive protein
mammary gland tumours
female dogs
Źródło:
Polish Journal of Veterinary Sciences; 2018, 21, 4; 691-696
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Male infertility and human environmental pollution
Autorzy:
Kołłątaj, Witold
Kołłątaj, Barbara
Karwat, Dorota Irena
Klatka, Maria
Kozyra, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/765459.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Mikołaja Kopernika w Toruniu. Wydział Nauk o Ziemi i Gospodarki Przestrzennej. Katedra Kultury Fizycznej
Tematy:
male reproductive organs
semen
male infertility
tumours
the environment
the pollution of the
Opis:
Introduction. Man is the only being that has created an artificial environment, or civilization. The development of civilization entails changes in the environment. The rapid growth of the impact of human economic activity has led to such changes that are able to threaten not only other living creatures but also themselves. Increasing environmental pollution are well-known factors negative influencing on human environment. Is now a global problem. Anthropogenic pollution contribute to the unfavorable demographic changes and grooving number of health problems of the population. Unfavourable demographic changes manifest themselves as not only increment in the number of deaths and malformations (defects in the reproductive organs), but also as decrement in the fertility rates being the consequence of increasing the growing problem of couples infertility. There is observed the increasing role of male factor in the couple infertility problem. In some developed countries its participation rate reaches 50%.Objective. The aim of the study is to assess the impact of environmental pollution on human development and reproductive function of male gonads.Material and methods. The study was carried out using the method of data analysis published in the works and scientific reports.Current state of knowledge. The paper presents information on identified environmental pollution with proven adverse effects on the development of the gonads and the their reproductive function. There are also known possible negative impacts of environmental pollution on carcinogenesis in male gonads.Wider awareness of the negative impact of environmental pollution and attempts put emphasis on primary prevention can give better long-term effects than increasing spending on the therapies of developmental disorders as well as gonadal dysfunctions symptoms including fertility problems.Conclusions.Among the environmental pollutants there are many chemicals adversely affecting the organogenesis as well as reproductive function of testicles.Many of these contaminants are pesticides or chemicals currently approved for use in agriculture and industry, including the food and cosmetics industry.Those chemicals, adversely affecting organogenesis and testicular generative function, are present in air, water and foods, packaged foods and everyday objects - including clothes (ingredients sponges), perfumes, creams and detergents.The increase in environmental pollution coincides with the deterioration of sperm quality and reduction in male infertility in highly civilized countries.Striving for continuous reduction of the environmental seems to be necessary to stop the growing problem of couples infertility.
Źródło:
Journal of Education, Health and Sport; 2017, 7, 4
2391-8306
Pojawia się w:
Journal of Education, Health and Sport
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Matrix metalloproteinases in urinary system tumours. Part I - Matrix metalloproteinases in renal cell carcinoma
Autorzy:
Młynarczyk, G.
Kudelski, J.
Darewicz, B.
Galewska, Z.
Romanowicz, L.
Powiązania:
https://bibliotekanauki.pl/articles/1918434.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
Extracellular matrix
matrix metalloproteinases
urinary tract tumours
renal clear cell carcinoma
Opis:
Extracellular matrix metalloproteinases - MMPs, also referred to as matrixines, provide a group of proteolytic enzymes. They belong to the family of endopeptidases that break down elements of extracellular matrix, resulting in its continuous remodelling. Their activity is regulated at multiple levels, while tissue inhibitors of metalloproteinases play a major role in this process. Metalloproteinases play a significant part in neoplastic processes due to their contribution to local tumour invasion and formation of distant metastases, as well as to angiogenesis Urinary tract tumours pose a significant diagnostic and therapeutic challenge and their incidence tends to grow every year. The aim of this part of review is to describe extracellular matrix and matrix metalloproteinases and to highlight the contribution of matrix metalloproteinases in the development of renal clear cell carcinoma.
Źródło:
Progress in Health Sciences; 2017, 7(1); 161-168
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Octreotide LAR in neuroendocrine tumours – a summary of the experience
Autorzy:
Kolasińska-Ćwikła, Agnieszka
Powiązania:
https://bibliotekanauki.pl/articles/1061844.pdf
Data publikacji:
2017
Wydawca:
Medical Education
Tematy:
neuroendocrine tumours
octreotide LAR
somatostatin analogues
Opis:
Neuroendocrine tumours are a rare and heterogeneous group of neoplasms. Most of the patients are diagnosed with locally advanced or metastatic disease and curative surgery is rarely an option. Somatostatin analogues have been shown to control the symptoms and growth of well-differentiated metastatic neuroendocrine tumours. Octreotide LAR is one of the treatment options.
Źródło:
OncoReview; 2017, 7, 1; 22-27
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wodogłowie wymagające implantacji układu zastawkowego u pacjentów z pierwotnymi guzami komór mózgowych – doświadczenia własne
Shunt-dependent hydrocephalus in patients with primary intraventricular
Autorzy:
Chodakowski, Paweł
Kapustka, Bartosz
Kotas, Adrian
Marcol, Wiesław
Wysokiński, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1035864.pdf
Data publikacji:
2017
Wydawca:
Śląski Uniwersytet Medyczny w Katowicach
Tematy:
guzy wewnątrzkomorowe
wodogłowie
zastawka komorowo-otrzewnowa
hydrocephalus
intraventricular tumours
ventricular shunt
Opis:
WSTĘP: Guzy wewnątrzkomorowe stanowią 1,5–3% wszystkich guzów mózgu. Są to zmiany o znacznej heterogenności pod względem rozpoznania histopatologicznego, symptomatologii oraz możliwych dostępów operacyjnych. Jednym z powikłań guzów wewnątrzkomorowych jest wodogłowie wymagające implantacji układu zastawkowego. Autorzy ocenili zależność rozwoju wodogłowia „zastawkozależnego” od lokalizacji guza, doszczętności resekcji, występowania wodogłowia przedoperacyjnego oraz zastosowania drenażu zewnętrznego komór mózgu. MATERIAŁ I METODA: Analizie retrospektywnej poddano 31 przypadków chorych z pierwotnie wewnątrzkomorowymi guzami mózgu, leczonych na Oddziale Neurochirurgii Szpitala w Jastrzębiu-Zdroju w latach 2002–2013. Wiek chorych wahał się od 17 do 75 lat. Grupa ta stanowiła 2,3% wszystkich pacjentów z guzami mózgu. Wybór dostępu operacyjnego był uzależniony od lokalizacji i charakteru zmiany oraz preferencji operatora. WYNIKI: 14 guzów (45,2%) położonych było w komorze czwartej, 9 (35%) w komorze trzeciej, 8 (25,8%) w komorach bocznych. Diagnostyka histopatologiczna wykazała: 6 przypadków ependymoma WHO II (19,4%), 4 subependymoma WHO I (12,9%), 3 carcinoma plexus choroidei WHO IV (9,7%), po dwa przypadki (6,5%) torbieli koloidowej i malignant ependymoma WHO III/IV oraz 10 innych rozpoznań. W 81% przypadków wykonano całkowitą resekcję guza. Wodogłowie przedoperacyjne występowało w 35% przypadków. U 42% chorych zastosowano drenaż komorowy zewnętrzny w okresie okołooperacyjnym. Wodogłowie pooperacyjne, wymagające implantacji układu zastawkowego, wystąpiło w 12,9% przypadków (4 chorych). Analiza statystyczna wykazała statystycznie istotną zależność jedynie między występowaniem takiego wodogłowia a lokalizacją guza (p = 0,041). WNIOSKI: Doszczętność operacyjna, obecność wodogłowia obturacyjnego przed zabiegiem oraz założenie drenażu komorowego zewnętrznego nie mają statystycznie istotnego wpływu na ryzyko rozwoju wodogłowia po zabiegu. Istotny statystycznie wpływ na powstanie „zastawkozależnego” wodogłowia w przebiegu pooperacyjnym ma jedynie lokalizacja guza z predylekcją do komory czwartej.
INTRODUCTION: Intraventricular tumours constitute 1.5–3% of all brain tumours. These tumours are a very heterogeneous group. There are many histologic types, various symptomatology and different surgical approaches. One of the possible complications is hydrocephalus, sometimes demanding shunt implantation. The authors estimated the relationship between shunt-dependent hydrocephalus and tumour location, the extension of resection, occurrence of preoperative hydrocephalus and the use of an external ventricular shunt. MATERIAL AND METHODS: A retrospective analysis of 31 cases with primary intraventricular tumours operated on in the Neurosurgical Department of the State Hospital in Jastrzebie-Zdroj between 2002 and 2013 was conducted. The age of the patients ranged between 17 and 75 years. This group constituted 2.3% of all patients with brain tumours. RESULTS: 14 tumours (45.2%) were located in the 4th ventricle, 9 (35%) in the 3rd ventricle, 8 (25.8%) in lateral ventricles. The histopathological diagnostics revealed: 6 cases of ependymoma WHO II (19.4%), 4 cases of subependymoma (12.9%), 3 cases of choroid plexus carcinoma, 2 coloid cysts (6.5%), 2 cases of malignant ependymoma WHO III/IV (6.5%) and 10 other diagnoses. Total resection was performed in 81% of tumours. Preoperative hydrocephalus appeared in 35% of cases. A perioperative external ventricular shunt was applied in 42% of patients. Shunt-dependent hydrocephalus appeared after 12.9% of operations (4 patients). Statistical analysis revealed a significant relationship between the existence of shunt-dependent hydrocephalus and tumour location (p = 0.041). CONCLUSION: The extent of resection, the occurrence of preoperative hydrocephalus and the use of an external ventricular shunt do not change the risk of the development of postoperative hydrocephalus. Only the location of the tumour has a statistically significant influence on the occurrence of shunt-dependent hydrocephalus.
Źródło:
Annales Academiae Medicae Silesiensis; 2017, 71; 32-37
1734-025X
Pojawia się w:
Annales Academiae Medicae Silesiensis
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluating the diagnostic accuracy of ultrasonography in differential diagnosis of adnexal tumours
Autorzy:
Smoleń, Agata
Stachowicz, Norbert
Czekierdowski, Artur
Powiązania:
https://bibliotekanauki.pl/articles/552437.pdf
Data publikacji:
2016
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
ultrasound
ovarian cancer
adnexal tumours.
Źródło:
Family Medicine & Primary Care Review; 2016, 3; 340-344
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ocena skuteczności oraz ryzyka powikłań „bezramowej” biopsji stereotaktycznej guzów mózgu opartej na neuronawigacji i badaniu MRI
Effiectiveness and safety of MRI based 'frameless' stereotactic biopsy of brain tumours
Autorzy:
Chodakowski, Paweł
Kapustka, Bartosz
Marcol, Wiesław
Kiwic, Grzegorz
Wysokiński, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1036720.pdf
Data publikacji:
2016
Wydawca:
Śląski Uniwersytet Medyczny w Katowicach
Tematy:
biopsja „bezramowa”
guzy mózgu
biopsja stereotaktyczna
neuronawigacja
'frameless' biopsy
brain tumours
stereotactic biopsy
neuronavigation
Opis:
INTRODUCTION: Stereotactic biopsy is a relatively commonly used tool for brain tumour diagnostics. A frame-based stereotactic biopsy is the standard, but the so-called 'frameless' biopsy, which is done by using a special neuronavigation system, seems to be a safe and convenient alternative. The authors have assessed the safety and effectiveness of an MRI based 'frameless' stereotactic biopsy of brain tumours. MATERIAL AND METHODS: 42 cases of patients, who underwent 'frameless' brain tumour biopsies in 2011–2013, were been retrospectively analysed. The biopsies were done by using BrainLab™ neuronavigation with VarioGuide and biopsy side-cut needles. The operation plan was based on a preoperative MRI head. In every case, at least 3 specimens various trajectories were taken. Pathological analysis was performed in the same place in every case. RESULTS: There were 85.7% cases with an exact histopathological result. 14.3% cases obtained a pathological result, but without exact diagnosis. One patient (2.4%) with astrocytoma WHO III died as a result of a perioperative intraventricular hemorrhage. Other clinically significant perioperative complications occurred in 2 cases (4.8%). The histopathological diagnostics revealed: 12 cases of GBM (28.6%), 8 cases of astrocytoma WHO III (19%), 10 cases of astrocytoma WHO II (23.8%), 1 case of metastasis (2.4%), 1 case of lymphoma (2.4%) as well as 2 other lesions (4.8%). Statistical analysis revealed no significant differences in the patients’ pre- and postoperative state. CONCLUSIONS: The 'frameless' biopsy is an effective and relatively safe way of diagnosing brain tumours. This type of biopsy takes less time to perform. It seems that it can be recommended as a convenient alternative to frame-based biopsy.
Źródło:
Annales Academiae Medicae Silesiensis; 2016, 70; 122-126
1734-025X
Pojawia się w:
Annales Academiae Medicae Silesiensis
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The mTOR signalling pathways in the pathogenesis and treatment of neuroendocrine tumours
Autorzy:
Kolasińska-Ćwikła, Agnieszka
Powiązania:
https://bibliotekanauki.pl/articles/1064993.pdf
Data publikacji:
2016
Wydawca:
Medical Education
Tematy:
mTOR inhibitors
mTOR signalling pathway
neuroendocrine tumours (NETs)
Opis:
Neuroendocrine tumours (NET) are a rare and heterogeneous group of neoplasms. The majority of patients are diagnosed with locally advanced or metastatic disease, and curative surgery is rarely an option. Treatment approaches involving targeted therapy, including the use of agents inhibiting the mTOR signalling pathways involved in neuroendocrine tumourigenesis, provide new therapeutic options for patients with NETs.
Źródło:
OncoReview; 2016, 6, 1; A37-42
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
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