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Tytuł:
Laryngeal sarcoidoisis – a case report
Autorzy:
Michałkowska-Pędzisz, Magdalena
Raczkowska-Łabuda, Karolina
Dobrzyński, Paweł
Powiązania:
https://bibliotekanauki.pl/articles/1399459.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
larynx
sarcoidosis
upper respiratory tract
Opis:
Introduction: Sarcoidosis is a multi-organ disease characterized by noncaseating granulomas. The lesions are usually localized within the lungs and hilar lymph nodes. The sarcoidosis of the upper respiratory tract (SURT) rate is estimated at 0.5–6%. The involvement of the larynx is extremely rare – it occurs in 1.2% of cases of SURT. Materials and methods. We present a case of a patient with laryngeal sarcoidosis. Results: A 48-year-old man had had a diagnosed of dysphonia for 5 years. A diagnosis of chronic hypertrophic laryngitis was made. Empirical course of methylprednisolone was attempted with a short-term improvement. Due to coexisting skin lesions, he was diagnosed with allergy. Chest CT showed moderately enlarged mediastinal and hilar lymph nodes as well as bilateral nodules around the hila. The bronchial biopsy showed no granulomas. Samples taken during microlaryngoscopy revealed sarcoid infiltrates. Conclusions and discussion: There is no unambiguous test confirming the diagnosis of sarcoidosis. It is a typical example of a diagnosis by exclusion. Laryngeal involvement is extremely rare and occurs in 1.2% of cases of SURT. The clinical course of the disease is often difficult to predict. In many patients, the lesion may undergo spontaneous regression. In patients poorly responding to steroid therapy or developing side effects, cytotoxic drugs may be considered.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2019, 8, 2; 38-42
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Empirical first-line antibioticotherapy in adult rural patients with acute respiratory tract infections
Autorzy:
Panasiuk, L
Lukas, W.
Paprzycki, P.
Powiązania:
https://bibliotekanauki.pl/articles/49984.pdf
Data publikacji:
2007
Wydawca:
Instytut Medycyny Wsi
Tematy:
human disease
rural patient
acute respiratory tract infection
antibiotic
therapy
respiratory tract infection
rural population
Opis:
The objective of the study was the evaluation of the frequency of occurrence of acute respiratory infections among rural population from the Lublin Region, and verifi cation of the appropriateness of the use of antibiotics in empirical fi rst-line therapy of these diseases. The analysis covered medical records concerning 1,839 patients selected from 27 rural health centres within the period of one year (1 September 2005–31 August 2006). As many as 656 patient visits were recorded, the reasons for which were qualifi ed by physicians as infections of the upper and lower airways. These disorders were diagnosed in 450 patients, which constituted 24.46% of the population examined. The following diagnoses were most frequently made: acute pharyngitis and tonsillitis (31.25% of the total number of diagnoses), acute upper respiratory infections of multiple and unspecifi ed sites (22.25%), and common cold (21.64%). Antibiotics were used in empirical fi rst-line therapy in as many as 82% of the total number of patients. The analysis showed that in the great majority of cases the use of antibiotics was inappropriate. If this situation persists, in the near future it will lead to an increase in the phenomenon of antibioticoresistance in Poland. In order to prevent this situation, it is necessary to carry out an extensive educational action concerning the hazardous effect of excessive use of antibiotics, both among physicians and the whole society.
Źródło:
Annals of Agricultural and Environmental Medicine; 2007, 14, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Measurement of the upper respiratory tract aerated space volume using the results of computed tomography
Autorzy:
Rybak, Adam
Zając, Andrzej
Kukwa, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/221767.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
CT studies
upper respiratory tract diagnostics
quantitative measurement of upper respiratory tract aerated space volume
Opis:
The paper presents the possibilities of quantitative analysis of results obtained from CT examination of organs and anatomical structures of the upper respiratory tract. The presented results of the analysis were obtained using proprietary software developed in the MATLAB 2018b environment (Image Processing toolbox). The software enables to visualize the original results of CT scan and, after evaluating the visible structures, enables to select the area to be subjected to quantitative analysis. After the initial identification of an area of interest requiring detailed diagnostics, its volume and the surface areas of individual cross-sections are calculated in the area separated for examinations. A graphical presentation of the analysis results - the surface areas of selected cross-sections possible to visualize in two- and three-dimensional space - enables quick analysis of changes in the examined region.
Źródło:
Metrology and Measurement Systems; 2019, 26, 2; 387-401
0860-8229
Pojawia się w:
Metrology and Measurement Systems
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Poles in pharmacy - source of knowledge and prevalence of over the counter usage
Autorzy:
Bandurska, Ewa
Zaleska, Judyta
Zarzeczna-Baran, Marzena
Powiązania:
https://bibliotekanauki.pl/articles/895595.pdf
Data publikacji:
2018-08-31
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
respiratory tract infections
Self Care
Nonprescription Drugs
Opis:
Self-medication is a procedure that is increasingly eagerly chosen by people all over the world, especially in common conditions (e.g. infections of upper respiratory tract). The main objective of this study was to determine the prevalence of self-medication and identify the sources of knowledge used by Polish society in searching for information on OTC medicines. The study was conducted in the group of 252 Internet users at working age (18-64 years) living in Poland (women n=208; 82.5%, men m=44; 17.5%) and used an original questionnaire consisting of 29 questions available on Internet from December 2016 to February 2017. According to the obtained results self-treatment was undertaken by 90.08% of Poles. Using OTC products was most prevalent among people with university education (p=0.01) and without children (p=0.03). Most popular source of knowledge on self-medication was own experience (n=149; 59.1%) and pharmacists’ advice (n=148; 58.7%). TV commercials were considered as unimportant for most of respondents (54.3%). Young women (18-26 years) most often used Internet to search for information about OTC drugs (p=0.03), young male trusted own experience (p=0.03) and men from older age groups (p=0.04) advice of a pharmacist. Self-medication can characterized as prevalent in Poland. People with lower levels of education used OTC medicines less often and therefore might benefit from stronger support of professionals.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 4; 1041-1049
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Prevalence of respiratory tract infections and differences in antibiotic treatment in young adults in various countries – preliminary data from the multinational online survey
Autorzy:
Kulczyński, Marcin
Chudzik, Robert
Tomaszewski, Mateusz
Marciniec, Michał
Papuć, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1164544.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Respiratory tract infections
antibiotic therapy
communicable diseases
Opis:
Respiratory tract infections are the most common communicable diseases, which include pharyngitis, otitis media, rhinosinusitis, laryngitis, bronchitis and pneumonia. Although the majority of pathogenic agents responsible for these conditions are cosmopolitan, the differences in frequency and severity of these diseases associated with climate and living conditions may appear. The aim of the study is to assess if there are significant differences in frequency and severity of respiratory tract infections in different countries. A survey, consisting of 49 questions involving the frequency of respiratory tract infections, antibiotics’ usage and demographic data was delivered to the users of a social network used to finding penfriends from abroad. Collected data was statistically analyzed and compared with climate conditions and economic indices in different countries. 462 respondents, aged 12-79 (mean age 25,15 ± 9,43, median 23) from 119 countries submitted their answers. First raw, preliminary data describe a prevalence of different types of respiratory tract infections and commonness of antibiotic therapy. This initial report with preliminary results of the survey should be a first step towards determining the differences in frequency and severity of respiratory tract infections, as well as in antibiotic treatment. Data gained during the survey need further analysis.
Źródło:
World Scientific News; 2018, 107; 46-57
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Oral immunomodulatory agents in the prevention of bacterial respiratory tract infections
Autorzy:
Jurkiewicz, Dariusz
Zielnik-Jurkiewicz, Beata
Powiązania:
https://bibliotekanauki.pl/articles/1400551.pdf
Data publikacji:
2016
Wydawca:
Index Copernicus International
Tematy:
respiratory tract infection
prevention
bacterial lysates
Opis:
Respiratory infections are a major health and economic problems in every country. Most infections are viral, bacterial in-fection but also are not rare. It should be emphasized that the respiratory tract infections are the cause of 20% of all med-ical consultations and 75% antibiotic treatment. To reduce the need for antibiotics, more and more attention is paid to the preparation increases the body’s resistance to bacterial infection. Non-specific multivalent vaccines containing killed at high temperature, bacterial cells or lysates. These preparations are non-specifically stimulate the overall immunity. They operate on the non-specific defense mechanisms, leading to increased antibody type IgA in secretions of the mu-cous membranes, phagocytic activity and IFN-γ. They may also stimulate the production of specific antibodies against bacterial antigens included in the formulation. Available on the Polish market oral preparations immunomodulatory of the best documented clinical efficacy are Luivac, Ribomunyl, Broncho-Vaxom and Ismigen. All lysates of bacterial strains are most often causing respiratory tract infections. Many clinical studies have shown that oral bacterial lysates reduce the risk of recurrent respiratory tract infections in adults and children and reduce the need for antibiotics.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2016, 5, 2; 21-25
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of fat mass and its correlation with abnormal blood pressure in children and adolescents
Autorzy:
Pirogowicz, Iwona
Ornat, Maciej
Pachołek, Krzysztof
Pawelak, Agnieszka
Domeredzka, Paulina
Jerczak, Bartosz
Gojny, Łukasz
Powiązania:
https://bibliotekanauki.pl/articles/552529.pdf
Data publikacji:
2017
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
hypertension
overweight
body composition
pediatrics
respiratory tract diseases.
Źródło:
Family Medicine & Primary Care Review; 2017, 3; 256-260
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Bacterial lysates in the prevention of respiratory tract infections
Autorzy:
Jurkiewicz, Dariusz
Zielnik-Jurkiewicz, Beata
Powiązania:
https://bibliotekanauki.pl/articles/1398206.pdf
Data publikacji:
2018
Wydawca:
Index Copernicus International
Tematy:
bacterial lysates
immunity
prevention
respiratory tract infection
Opis:
Bacterial lysates stimulate the general immunity of the body in a non-specific way. They act on non-specific defense mechanisms, leading to an increase in type A antibody in mucous membranes, phagocytic activity and INF-ƴ production. They can also stimulate the production of specific antibodies against the bacterial antigens that make up the preparation. The oral immunomodulatory preparations with the best documented clinical efficacy available on the Polish market are Ismigen, Broncho-Vaxom, Ribomunyl and Luivac. They are all lysates of bacterial strains that most often cause respiratory tract infections. In many clinical trials, oral bacterial lysates have been shown to minimize the risk of recurrent respiratory infections in children and adults and reduce the need for antibiotics.
Źródło:
Polish Journal of Otolaryngology; 2018, 72, 5; 1-8
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Diagnostic difficulties with COVID-19 in a patient after total laryngectomy
Trudności diagnostyczne w rozpoznaniu COVID-19 u pacjenta po laryngektomii całkowitej
Autorzy:
Czech, Joanna
Burduk, Paweł
Wierzchowska, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/1399027.pdf
Data publikacji:
2021-06-22
Wydawca:
Index Copernicus International
Tematy:
COVID-19
laryngectomy
lower respiratory tract
SARS-CoV-2
upper respiratory tract
dolne drogi oddechowe
górne drogi oddechowe
laryngektomia
Opis:
Coronavirus disease (COVID-19) is caused by the SARS-CoV-2 virus and often presents with flu-like symptoms that can have varying degrees, which may subsequently lead to acute respiratory distress (ARDS). The genetic material of the virus in samples of respiratory secretions is identified by way of basic diagnostic tests. Due to the altered course of the respiratory tract, patients after total laryngectomy require special attention in the diagnosis of SARS-CoV-2 infection. We present a case of a patient after laryngectomy who obtained different results of COVID-19 tests depending on the site of sampling.
Choroba COVID-19 wywoływana jest przez wirusa SARS-CoV-2 i często manifestuje się objawami grypopodobnymi, które mogą przebiegać z różnym nasileniem. W dalszej kolejności może prowadzić do ostrej niewydolności oddechowej (ARDS). Podstawowe testy diagnostyczne identyfikują materiał genetyczny wirusa w próbkach wydzielin z dróg oddechowych. Chorzy po laryngektomii całkowitej z uwagi na zmieniony przebieg dróg oddechowych wymagają szczególnej uwagi pod względem diagnostyki w kierunku zakażenia SARS-CoV-2. W naszej pracy przedstawiamy przypadek pacjenta po laryngektomii, u którego uzyskano różne wyniki testów w kierunku COVID-19 w zależności od miejsca pobrania próbek. Słowa kluczowe: SARS-CoV-2, laryngektomia, drogi oddechowe
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2021, 10, 2; 44-47
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Incidence of respiratory tract infections and antibiotic use in primary health care
Autorzy:
Pietrzykowska, Małgorzata
Nowicka-Sauer, Katarzyna
Gutknecht, Piotr
Siebert, Janusz
Powiązania:
https://bibliotekanauki.pl/articles/553127.pdf
Data publikacji:
2016
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
respiratory tract infections
antimicrobial therapy
general practitioner (GP).
Źródło:
Family Medicine & Primary Care Review; 2016, 3; 332-335
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Choroby układu oddechowego – jak poprawić dostępność i wyniki leczenia?
Diseases of the Respiratory System – Ways to Improve Access to and Results of Treatment
Autorzy:
Wasilewski, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/416798.pdf
Data publikacji:
2017-04
Wydawca:
Najwyższa Izba Kontroli
Tematy:
diseases of the respiratory system
chronic lung diseases
respiratory tract
smoking
healthcare
Opis:
According to epidemiological forecasts, the incidence and mortality related to chronic diseases of the respiratory tract will be increasing systematically due to, among others, the growing number of persons above the age of 65, the pollution of the natural environment and smoking. In the opinion of the World Health Organisation, smoking is the main reason for diseases associated with the progress of civilisation, closely related to the respiratory tract. The Supreme Audit Office, taking the above factors into account, conducted the first coordinated audit in this area.
Źródło:
Kontrola Państwowa; 2017, 62, 2 (373); 72-81
0452-5027
Pojawia się w:
Kontrola Państwowa
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Detection of the influenza virus yesterday and now
Autorzy:
Woźniak-Kosek, Agnieszka
Kempińska-Mirosławska, Bogumiła
Hoser, Grażyna
Powiązania:
https://bibliotekanauki.pl/articles/1039248.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
influenza
virus
detection method
diagnostics
PCR
viral respiratory tract infection
Opis:
Demographic changes and the development of transportation contribute to the rapid spread of influenza. Before an idea of a 'person to person' spread appeared, divergent theories were developed to explain influenza epidemics in the past. Intensified virological and serological tests became possible after isolation of the human influenza virus in 1933. The first influenza virus detection methods were based on its isolation in egg embryos or cell lines and on demonstration of the presence of the viral antigens. Molecular biology techniques associated with amplification of RNA improved the quality of tests as well as sensitivity of influenza virus detection in clinical samples. It became possible to detect mixed infections caused by influenza types A and B and to identify the strain of the virus. Development of reliable diagnostic methods enabled fast diagnosis of influenza which is important for choosing an appropriate medical treatment.
Źródło:
Acta Biochimica Polonica; 2014, 61, 3; 465-470
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Differentiation by random amplified polymorphic DNA-polymerase chain reaction (RAPD-PCR) of Candida albicans isolated from upper respiratory tract in patients with non-small cell lung cancer
Autorzy:
Biernasiuk, Anna
Korona-Głowniak, Izabela
Grzegorczyk, Agnieszka
Malm, Anna
Powiązania:
https://bibliotekanauki.pl/articles/1039202.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
RAPD-PCR
Candida albicans
upper respiratory tract
genetic diversity
Opis:
Cancer patients are predisposed to fungal infections caused by Candida albicans, especially to oral or respiratory tract candidiasis. The aim of this study was to estimate genetic diversity by RAPD-PCR (random amplified polymorphic DNA-polymerase chain reaction) of C. albicans isolated from upper respiratory tract of 100 patients with non-small cell lung cancer. Among 52 strains, 34 genotypes were defined. 10 clusters comprising 28 (53.85%) isolates with similarity coefficient ≥ 80% were formed. The remaining 24 (46.15%) isolates represented individual genotypes. The RAPD-PCR technique revealed genomic variability within C. albicans isolated from upper respiratory tract of the cancer patients.
Źródło:
Acta Biochimica Polonica; 2014, 61, 4; 727-729
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Non specific vaccines – immunostimulation in patients with recurrent respiratory infections
Autorzy:
Paśnik, Jarosław
Powiązania:
https://bibliotekanauki.pl/articles/1398623.pdf
Data publikacji:
2016
Wydawca:
Index Copernicus International
Tematy:
recurrent respiratory tract infections
innate immunity
acquired immunity
immunostimulation
Opis:
Recurrent respiratory tract infections in children are the most common cause of outpatient visits. Due to the necessity of treatment of chronic, frequent use of antibiotics and the dangers of complications are a major clinical problem. Big hopes are now with the possibility of the use of immunostimulation as prevention of these infections. The paper discusses the most important methods of stimulation of the immune system in children. In the light of previous reports were evaluated effects of this type of therapy.
Źródło:
Polish Journal of Otolaryngology; 2016, 70, 6; 31-39
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The utility of a modified technique for lower respiratory tract sampling in COVID-19 ICU and review of diagnostic approaches in suspected ventilator associated pneumonia
Autorzy:
Anokar, Anita
Jedge, Prashant
Shah, Jignesh
Chougale, Samruddhi
Powiązania:
https://bibliotekanauki.pl/articles/1918273.pdf
Data publikacji:
2021-09-30
Wydawca:
Towarzystwo Pomocy Doraźnej
Tematy:
Closed suction system
ventilator-associated pneumonia
COVID-19
lower respiratory tract sampling
Opis:
INTRODUCTION: Lower respiratory tract (LRT) sampling is an aerosol generating procedure. In COVID 19 pandemic, guidelines have advocated caution against all aerosol generating procedures. However, microbial cultures on tracheobronchial aspirates are important to guide antibiotic usage in ventilator-associated pneumonia (VAP). MATERIAL AND METHODS: In our tertiary care COVID-19 intensive care unit (ICU), a protocol was set for using closed suction system for timely LRT sampling in VAP and to reduce the risk of exposure to respiratory secretions. Timing of sample collection was as per intensivist discretion following CDC VAP definition. This prospective study was conducted between June to November 2020, to assess the utility of this technique in diagnosis of suspected VAP. Microbiological and clinico-radiological parameters were documented. Heavy growth (>105 cfu/mL) on semiquantitative culture was taken as significant. RESULTS: Total 69 samples generated from 63 patients were analyzed. Mean age 54.48 years and 77.78% of patients had one or more comorbidities. Average duration of invasive ventilation prior to the first culture was 7.14 ± 4.36 days. Progressive radiological worsening at the time of sample collection was in 92.75% (64 of 69 episodes). Microbiological diagnosis of VAP was confirmed in 76.81%. Culture reports guided antibiotic change. Insignificant culture growth in 13.06%. The positivity rate for early and late (>4days) samples were 69.56% and 80.43% respectively. 95% of culture isolates were Gram negative microorganisms. Most common being Acinetobacter baumannii (41.67%) and Klebsiella pneumoniae (31.66%) in both early and late VAP. Around 85% were multidrug resistant organisms. There were no significant adverse events related to sampling technique. CONCLUSIONS: Lower respiratory tract sampling using closed suction system is easy to execute and minimizes procedure related risk to both patient and health care workers in COVID-19 ICU. Gram negative MDR pathogens are prevalent in both early and late VAP. Need further comparative study to understand effectiveness of this technique against other conventional techniques in VAP diagnosis.
Źródło:
Critical Care Innovations; 2021, 4, 3; 1-14
2545-2533
Pojawia się w:
Critical Care Innovations
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Comorbidities and clinical outcomes of a lung cancer screening trial participants with chronic obstructive pulmonary disease in three-year follow-up
Autorzy:
Undrunas, Aleksandra
Bąk, Agata
Kasprzyk, Piotr
Dziedzic, Robert
Dziurda, Dominik
Rzyman, Witold
Gierlotka, Marek
Kuziemski, Krzysztof
Powiązania:
https://bibliotekanauki.pl/articles/25714585.pdf
Data publikacji:
2022-10-03
Wydawca:
Gdański Uniwersytet Medyczny
Tematy:
chronic obstructive pulmonary disease
diagnostic radiology
oncology
lung cancer
respiratory tract
screening
Opis:
Background To improve the effectiveness of lung cancer screening using low-dose computed tomography (LDCT), the presence of smoking-related comorbidities that may significantly affect mortality in this group should be taken into account. Material and methods A questionnaire survey and spirometry tests were conducted in a group of 730 respondents as part of a lung cancer screening study between 2016 and 2018. People diagnosed with COPD underwent a three-year follow-up to assess the incidence of medical events. Results Our study confirmed that cardiovascular diseases (CVDs) were the most common comorbidities in patients who were diagnosed with COPD and participated in LDCT lung cancer screening. Among the CVDs, the most common were arterial hypertension (45.8%) and coronary artery disease (12.5%). Tobacco-related diseases (e.g. CVD, lung cancer, and exacerbations of COPD) were the leading causes of emergency department visits and hospitalizations. The number of visits due to COPD in specialized clinics more than doubled in the observed period. Conclusions Properly planned screening tests allow not only for the detection of the disease for which they were designed but also for the assessment of comorbidities. In patients undergoing lung cancer screening, it is justified to extend the diagnostics to include spirometry.
Źródło:
European Journal of Translational and Clinical Medicine; 2022, 5, 2; 24-30
2657-3148
2657-3156
Pojawia się w:
European Journal of Translational and Clinical Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Place of phytotherapy in the treatment of acute infections of upper respiratory tract and upper gastrointestinal tract
Autorzy:
Pietruszewska, Wioletta
Barańska, Magda
Wielgat, Jakub
Powiązania:
https://bibliotekanauki.pl/articles/1398294.pdf
Data publikacji:
2018
Wydawca:
Index Copernicus International
Tematy:
acute rhinosinusitis
acute pharyngitis
phytotherapy
acute infections of an upper respiratory tract and upper gastrointestinal tract
Opis:
Acute infections of the upper respiratory tract and upper gastrointestinal tract (mouth and throat) are still the most common reason for reporting to the general practitioner or ENT specialist. Despite the fact that the most common causative agent of these diseases is a virus, antibiotics are still flavored in about 60-80% of patients who report to the doctor. In consensuses such as EPOS, WHO reports and other local/ / national reports, there is a need to limit antibacterial treatment for and to replace it with symptomatic and anti-inflammatory drugs. In addition to intranasal steroids and mucocutaneous decongestants, supplementary treatment should be considered which resolves persistent symptoms. Plant preparations are used here. The growing role of rational phytotherapy is emphasized, especially due to the most frequent the etiological factor of these infections, i.e. viruses. Modern phytotherapy is a part of pharmacology, and all preparations based on plants meet the standards for of medicines and are subject to standard registration procedures. The article discusses the use and mechanism of action of selected herbs, among others: sorrel, elderberry, yarrow, and horsetail in the treatment of upper respiratory tract infections and upper gastrointestinal tract. The phytotherapy shows good efficacy and tolerance and can be used both in children and adults in recurrent infections of the upper respiratory tract. It is worth paying attention to the combined preparations, the components of which have the effects confirmed by randomized trials and long-term registration for use in treatment, both during the first signs of cold and its further duration, and supportive as support in chronic inflammation especially of the paranasal sinuses.
Źródło:
Polish Journal of Otolaryngology; 2018, 72, 4; 42-50
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ditlenek azotu. Dokumentacja proponowanych wartości dopuszczalnych wielkości narażenia zawodowego
Nitrogen dioxide
Autorzy:
Starek, A.
Powiązania:
https://bibliotekanauki.pl/articles/138057.pdf
Data publikacji:
2005
Wydawca:
Centralny Instytut Ochrony Pracy
Tematy:
ditlenek azotu
układ oddechowy
działanie klastogenne
nitrogen dioxide
respiratory tract
clastogenic action
Opis:
Ditlenek azotu (NO2) jest gazem, który dosyć często występuje w środowisku pracy i środowisku komunalnym. Związek ten powstaje podczas: spalania substancji organicznych zawierających azot, detonacji materiałów wybuchowych, obróbki elektrochemicznej metali oraz pracy silników dieslowskich. W 2001 r. w Polsce było 736 osób narażonych zawodowo na ditlenek azotu o stężeniu większym od obowiązującej wartości NDS. Zarówno u ludzi, jak i u zwierząt laboratoryjnych narządem krytycznym dla ditlenku azotu jest układ oddechowy. Ostre zatrucie tym związkiem manifestuje się obrzękiem płuc prowadzącym nawet do zejścia śmiertelnego; związek jest klasyfikowany jako substancja toksyczna. Ditlenek azotu może działać klastogennie (czynnik powodujący załamania chromosomów i ich następstwa w postaci pozyskania, utraty lub przemieszczenia części chromosomów) oraz może sprzyjać rozwojowi nowotworów. Związek ten może również negatywnie wpływać na ontogenetyczny rozwój organizmu. Podstawą wartości najwyższego dopuszczalnego stężenia (NDS) ditlenku azotu są wyniki dobrze udokumentowanych badań przeprowadzonych w przemyśle, których wyniki posłużyły do wykazania pneumotoksycznego działania związku. Wartość NDS ditlenku azotu obliczono na podstawie wartości LOAEL (2,95 mg/m3) i dwóch współczynników niepewności. Na podstawie wartości NDS obliczono również wartość najwyższego dopuszczalnego stężenia chwilowego (NDSCh) ditlenku azotu. Po analizie wyliczeń zaproponowano przyjęcie wartości NDS ditlenku azotu wynoszącej 0,7 mg/m3 oraz wartości NDSCh wynoszącej 1,5 mg/m3.
Nitrogen dioxide (NO2) is a gas commonly present in both occupational and general environments. It is a product of fired materials containing nitrogen. In 2001 in Poland 736 workers were exposed to NO2 at a level above the MAC value. Respiratory tract is a critical organ for toxic action of NO2 in both humans and animals. This chemical is a clastogen. In the industry pneumotoxic effects in workers exposed to NO2 at level of 0.8 – 5.1 mg/m3 were observed. The MAC (TWA) value of 0.7 mg/m3 was calculated on the basis of the LOAEL value (2.95 mg/m3) and relevant uncertainty factors. The MAC (STEL) value was established by calculation at level of 1.5 mg/m3.
Źródło:
Podstawy i Metody Oceny Środowiska Pracy; 2005, 3 (45); 49-64
1231-868X
Pojawia się w:
Podstawy i Metody Oceny Środowiska Pracy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The role of bronchoscopy in the diagnosis of lower respiratory tract infections
Autorzy:
Mierzejewski, Michał
Krenke, Rafał
Powiązania:
https://bibliotekanauki.pl/articles/1401689.pdf
Data publikacji:
2016
Wydawca:
Index Copernicus International
Tematy:
bronchoscopy
lower respiratory tract infections
bronchoalveolar lavage
opportunistic infections
tuberculosis
pulmonary mycoses
Opis:
Bronchoscopy was introduced into clinical practice over 100 years ago. Due to technological advances, diagnostic capabilities of current bronchoscopy are not limited to the trachea and proximal bronchi but also include the peripheral airways as well as various anatomical structures located outside the bronchi. A wide range of available techniques that include bronchoalveolar lavage, protected microbiological brush, transbronchial biopsy of the lungs and mediastinal lymph nodes makes bronchoscopy useful in diagnosing various lower respiratory tract infections. For example, the collection of high quality biological samples for microbiological examination plays a crucial role when treating patients with nosocomial pneumonia. Bronchoscopy may provide the samples directly from the site of infection. In immunocompromised hosts bronchoscopy is routinely used as the diagnostic tool in lower respiratory tract infections. Due to implementation of novel therapies, the number of immunocompromised patients is steadily increasing, hence there are growing needs for effective diagnosis of opportunistic pulmonary infections. In the specific group of lung transplant recipients, bronchoscopy play a crucial role in monitoring the rejection process and also in differentiating between the rejection and pulmonary infections. Bronchoscopy is also useful in diagnosing tuberculosis or nontuberculous pulmonary infections. This particularly refers to patients who are unable to produce sputum for microbiological examination.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2016, 5, 3; 1-6
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Czynniki ryzyka związane ze stylem i jakością życia a częstość zachorowań na nowotwory złośliwe górnych dróg oddechowych w mikroregionie Mysłowice, Imielin i Chełm Śląski
Risk factors associated with life style and quality of life and frequency of incidence of malignant neoplasms of upper respiratory tract in micro-region of Mysłowice, Imielin and Chełm Śląski
Autorzy:
Stockfisch, Jerzy
Markowski, Jarosław
Pilch, Jan
Zemła, Brunon
Dziubdziela, Włodzimierz
Likus, Wirginia
Bajor, Grzegorz
Powiązania:
https://bibliotekanauki.pl/articles/1035099.pdf
Data publikacji:
2014
Wydawca:
Śląski Uniwersytet Medyczny w Katowicach
Tematy:
nowotwory złośliwe
górne drogi oddechowe
czynniki ryzyka
upper respiratory tract
malignant tumors
risk factors
Opis:
INTRODUCTION The most frequent risk factors of malignant neoplasms in the upper respiratory tract (MNURT) are tobacco smoking, excessive consumption of spirits with a high percentage of alcohol, vitamin A deficiency, genetic pre-disposition, as well as exposure to carcinogenic compounds present in the environment. The aim of the study was to analyze the life style and quality of life factors, and their influence upon the incidence of MNURT within the micro-region of Mysłowice. MATERIAL AND METHODS The paper presents a retrospective analysis of MNURT incidence in the towns of Mysłowice, Imielin, and Chełm Śląski, on the basis of materials concerning patients treated in the Laryngologic Ward of the Mysłowice hospital, in the years 1995–2004. On the basis of patients’ data, the authors carried out analysis of MNURT incidence in correlation with risk factors related to the work in which patients were engaged, the number of cigarettes smoked as function of time, consumption of strong alcohols, social and living conditions, place of employment, current place of residence, as well as education. RESULTS Cigarette smoking and/or consumption of strong alcohols are the main risk factors in MNURT. The level of education as well as socio-economic status are also significant risk factors in MNURT incidence. CONCLUSIONS The firm conclusion of the paper is that the increased number of cases of MNURT in the micro-region of Mysłowice, Imielin, and Chełm Śląski may be due to the living conditions, higher level of consumption of strong alcohols, excessive cigarette smoking, as well as low socio-economic status of the examined patients.
WSTĘP Najczęściej wymienianymi czynnikami ryzyka w nowotworach złośliwych górnych dróg oddechowych (NZGDO) jest palenie tytoniu, nadmierne spożycie wysokoprocentowego alkoholu, niedobór witaminy A, predyspozycja genetyczna i narażenie na działanie związków rakotwórczych pochodzenia środowiskowego. Celem pracy była analiza czynników związanych ze stylem i jakością życia oraz ich wpływ na zachorowalność na NZGDO w obrębie mikroregionu Mysłowic. MATERIAŁ I METODY W pracy przedstawiono retrospektywną analizę zachorowań na NZGDO w obrębie miejscowości: Mysłowice, Imielin i Chełm Śląski na podstawie danych oddziału laryngologicznego szpitala w Mysłowicach z lat 1995–2004. Dokonano analizy zapadalności na NZGDO w korelacji z czynnikami ryzyka związanymi z wykonywaną pracą, liczbą wypalanych papierosów, czasem palenia, spożyciem wysokoprocentowego alkoholu, warunkami socjalno-bytowymi, miejscem zatrudnienia i aktualnym miejscem zamieszkania, chorobami współistniejącymi i poziomem wykształcenia. WYNIKI Z analizy wynika, że głównymi czynnikami ryzyka w NZGDO były palenie papierosów i/lub spożywanie wysokoprocentowego alkoholu. Liczba i rodzaj wypalanych papierosów wiąże się istotnie ze wzrostem zapadalności na NZGDO. Znaczącymi czynnikami ryzyka są także poziom wykształcenia i status społeczno-ekonomiczny: im wyższy poziom wykształcenia, tym mniejsze ryzyko zachorowania. WNIOSKI Zwiększona liczba zachorowań na NZGDO w mikroregionie Mysłowic, Imielina i Chełmu Śląskiego może wiązać się ze zwiększonym spożyciem wysokoprocentowych alkoholi, nadmierną liczbą wypalanych papierosów oraz niskim statusem społeczno-ekonomicznym badanych chorych. W pracy potwierdzono wpływ uznanych czynników ryzyka na częstość zachorowań na NZGDO.
Źródło:
Annales Academiae Medicae Silesiensis; 2014, 68, 1; 38-46
1734-025X
Pojawia się w:
Annales Academiae Medicae Silesiensis
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The perspective of immunoprophylaxis and selected immunological issues in the course of the turkey rhinotracheitis
Autorzy:
Smialek, M.
Tykalowski, B.
Stenzel, T.
Koncicki, A.
Powiązania:
https://bibliotekanauki.pl/articles/32005.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
perspective
immunoprophylaxis
turkey rhinotracheitis
animal infection
vaccination
upper respiratory tract
animal disease
turkey
Opis:
This review article presents immunological issues in the course of the turkey rhinotracheitis (TRT) emphasizing local immunity mechanisms, both humoral and cell-mediated, in the upper respiratory system. Studies on the influence of the humoral immunity in the course of infection and vaccinations against TRT have revealed many times the absence of correlation between the titre of specific IgY anti-aMPV (avian Metapneumovirus) antibodies in the serum and in the upper respiratory washings and the immunity against the occurrence of the clinical form of the TRT. Considering the above, T cells are increasingly often regarded as the main factor involved in the upper respiratory immunity against the TRT. However, there have been just a few reports on the role of the T cells in the local immunity processes in the infection with aMPV in turkeys. Additionally, studies of the T-cell-associated immunity against the TRT have given ambiguous results. Immunoprophylaxis issues against the aMPV infections are a significant part of the work where the authors confront current vaccination programmes against the perspectives of use of the future vaccines against the TRT. Future vaccines should face the following criteria: absence of the risk of immunosuppressive effect and reversion of vaccine strains virulence, ease-of-use combined with the possibility of administration of the vaccine to the large numbers of turkeys. The leading role in future vaccination programs for birds against the TRT is likely to be played by the in ovo technique and the recombinant vaccines. Great hopes are also linked with the development of subunit vaccines against the aMPV.
Źródło:
Polish Journal of Veterinary Sciences; 2012, 15, 1
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antibiotic susceptibility of bacteria isolated from respiratory tract of pigs in Poland between 2004 and 2008
Autorzy:
Markowska-Daniel, I
Urbaniak, K.
Stepniewska, K.
Pejsak, Z.
Powiązania:
https://bibliotekanauki.pl/articles/30384.pdf
Data publikacji:
2010
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Polska
pig
respiratory tract
bacteria
isolation
antibiotic susceptibility
animal health
productivity
animal production
Opis:
Antibiotic susceptibility of bacteria isolated from nasal swabs and lungs of pigs, to 16 commonly used antibiotics, was determined by disc diffusion test, ß-lactams showed the best activity against Streptococcus suis (S. suis) (> 99% of susceptible strains). The lowest sensitivity of S. suis was evidenced to: tylosin, tetracycline and neomycin (50%, 40% and 25%, respectively). Isolates of Escherichia coli (E. coli) demonstrated the highest susceptibility to cephalosporin (85% strains), gentamicin and norfloxacin (over 74%). The lowest susceptibility of E. coli was demonstrated to tiamulin and penicillin (11.3% and 1.9%, respectively). Over 80% of Actinobacillus pleuropneumoniae (App) strains were susceptible to all antibiotics tested. The highest resistance of App, but demonstrated by below 20% of tested isolates only, was evidenced to neomycin and LxS. Isolates of Pasteurella multocida (Pm), Haemophilus parasuis (Hps) and Arcanobacterium pyogenes (A. pyogenes) were highly susceptible to the most antibiotics included in the analysis. The comparison of the in vitro susceptibility of pathogens to the chemotherapeutics used on Polish farms for the therapy of bacterial infection of pigs within the last five years and the last 10 years, showed an increasing percent of E. coli and S. suis strains resistant to commonly used antibiotics. It is also shown that Pm, Hps, App and A. pyogenes isolates were continuously susceptible to the most chemotherapeutics applied.
Źródło:
Polish Journal of Veterinary Sciences; 2010, 13, 1; 29-36
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Molecular analysis of a fragment of gene E1B 19K of canine adenovirus 2 (CAV-2) isolated from dogs with symptoms of cough
Autorzy:
Kalinowski, M.
Adaszek, L.
Miloszowska, P.
Skrzypczak, M.
Zietek-Barszcz, A.
Kutrzuba, J.
Gradzki, Z.
Winiarczyk, S.
Powiązania:
https://bibliotekanauki.pl/articles/31384.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
molecular analysis
gene
canine adenovirus 2
isolation
dog
disease symptom
cough
upper respiratory tract infection
Opis:
The aim of this study was to perform molecular analysis of canine adenovirus 2 (CAV-2) E1B 19K gene fragment isolated from 20 dogs of various breeds (12 males and 8 females aged 1-9 years), with clinical symptoms of upper respiratory tract infections, from the Lubelszczyzna region. Nasal swabs were taken from dogs. DNA of CAV-2 was detected using the PCR method in 16 swabs. All PCR products were sequenced, and the obtained sequences were compared with each other and with the sequence of the E1B 19K gene of the CAV-2 strain from an online database of NCBI GenBank: AC 000003. Based on analysis of the obtained sequences, three polymorphic variants of CAV-2 (No.1-3) with homology of 78 - 100% were distinguished. The nucleotide and amino acid sequences of the most frequently represented polymorphic variant, No. 1, differed from the sequences of polymorphic variant No. 2 with one substitution. The nucleotide and amino acid sequence of the E1B 19K gene of CAV-2 AC 000003 differed from the analogous sequences of representatives of variant No. 1 with 44 nucleotide and 19 amino acid substitutions. The small number of nucleotide differences in the E1B 19K CAV-2 gene among the examined own isolates, compared with AC 000003, suggest that the infections in dogs were caused by a relatively genetically stable virus which occurs in eastern Poland.
Źródło:
Polish Journal of Veterinary Sciences; 2012, 15, 3
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Incidence of Betulaceae pollen and pollinosis in Zagreb, Croatia, 2002-2005
Autorzy:
Peternel, R
Milanovic, S.M.
Hrga, I.
Mileta, T.
Culig, J.
Powiązania:
https://bibliotekanauki.pl/articles/50670.pdf
Data publikacji:
2007
Wydawca:
Instytut Medycyny Wsi
Tematy:
human disease
Croatia
respiratory tract
pollen grain
aerobiology
Betulaceae
pollinosis
allergy
Zagreb
pollen allergy
Opis:
Pollen allergy is characterized by seasonal allergic manifestations affecting patients during the plant pollen season. The aim of this study was to analyze the Betulaceae pollen pattern in Zagreb (2002-2005) and to determine the incidence of sensitization to these pollen types in patients with seasonal respiratory allergy. Twenty-four-hour pollen counts were carried out using volumetric procedure. Skin prick test were performed on a total of 864 patients aged 18-80< in Zagreb between 2 January – 31 December 2004. Pollen of the representatives of the family Betulaceae accounted for a signifi cant proportion of total pollen (34% on an average), predominated by Betula pollen and considerably lower proportion of Alnus sp. and Corylus sp. pollen. Alder and hazel pollen fi rst occurred in the air in February throughout the study period. The highest airborne pollen concentration of these taxa was recorded in February and March. The birch pollen season generally peaked in April. Only 2.67% of patients showed birch pollen monosensitization. The proportion of patients with polysensitization to Betulaceae pollen was considerably greater (12.88%), whereas polysensitization to Betulaceae, Poaceae and Ambrosia pollen was recorded in the highest proportion of patients (26.23%). According to age, the highest and lowest rate of allergy was recorded in the 31-50 and >51 age groups, respectively (46.22% vs 23.12%). Female predominance was observed across all age groups. The patients with monosensitization to birch pollen had the most severe symptoms in April. In the patients with poylsensitization to alder, hazel and birch pollen who developed cross-reaction, initial symptoms occurred as early as February, with abrupt exacerbation in March and April. The most severe condition was observed in the patients allergic to birch, hazel, alder, grass and ragweed pollen, with symptoms present throughout the year and exacerbation in spring and late summer months.
Źródło:
Annals of Agricultural and Environmental Medicine; 2007, 14, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Equine herpesvirus type 1 (EHV-1) replication in primary murine neurons culture
Autorzy:
Cymerys, J.
Dzieciatkowski, T.
Slonska, A.
Bierla, J.
Tucholska, A.
Chmielewska, A.
Golke, A.
Banbura, M.W.
Powiązania:
https://bibliotekanauki.pl/articles/31974.pdf
Data publikacji:
2010
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
replication
animal disease
horse
equine herpesvirus 1
respiratory tract infection
neurological disorder
abortion
neuron
Opis:
Equine herpesvirus-1 (EHV-1) infections cause significant economic losses for equine industries worldwide as a result of abortion, respiratory illness, and neurologic disease in all breeds of horses. The occurrence of abortions caused by EHV-1 has repeatedly been confirmed in Poland, but neurological manifestations of the infection have not been described yet. Also it is unknown how the infection of neurons with non-neuropathogenic strains is regulated. To further understand the virus- neuron interaction we studied two strains of EHV-1 in murine primary neuron cell cultures. Both strains were isolated from aborted fetuses: Rac-H, a reference strain isolated by Woyciechowska in 1959 (Woyciechowska 1960) and Jan-E isolated by Bańbura et al. (Bańbura et al. 2000). Upon infection of primary murine neuronal cell cultures with Jan-E or Rac-H strains, a cytopathic effect was observed, manifested by a changed morphology and disintegration of the cell monolayer. Positive results of immunofluorescence, nPCR and real-time PCR tests indicated high virus concentration in neurons, meaning that both EHV-1 strains were likely to replicate in mouse neurons in vitro without the need for adaptation. Moreover, we demonstrated that some neurons may survive (limited) virus replication during primary infection, and these neurons (eight weeks p.i.) harbour EHV-1 and were still able to transmit infection to other cells.
Źródło:
Polish Journal of Veterinary Sciences; 2010, 13, 4
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
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