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Wyświetlanie 1-15 z 347
Tytuł:
A Contribution to the Study of Traces of Psychotropic Substances Inside Miniature Vessels and Collared Flasks of the Eneolithic Funnel Beaker culture (FBC) from Poland
Autorzy:
Taras, Halina
Zakościelna, Anna
Osak, Marcin
Buszewicz, Grzegorz
Teresiński, Grzegorz
Powiązania:
https://bibliotekanauki.pl/articles/38620704.pdf
Data publikacji:
2023
Wydawca:
Uniwersytet Rzeszowski. Instytut Archeologii Uniwersytetu Rzeszowskiego. Muzeum Okręgowe w Rzeszowie
Tematy:
psychoactive substances
miniature vessels
Eneolithic
SE group of the FBC
Polska
GC-MS/MS
LC-MS/MS
Opis:
The text presents the results of laboratory analyses conducted on vegetal intoxicating substances identified on the walls of selected pottery forms discovered at Polish sites attributed to the south-eastern group of the FBC. The samples taken from miniature vessels and collared flasks were examined using the GC-MS/MS method (triple quadrupole) and then the reference method LC-MS/MS (linear ion trap). As a result of the research, psychotropic substances were identified in four samples: papaverine, scopolamine and atropine.  
Źródło:
Analecta Archaeologica Ressoviensia; 2023, 18; 97-102
2084-4409
Pojawia się w:
Analecta Archaeologica Ressoviensia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analytical strategies for assessing occupational exposure to antineoplastic drugs in healthcare workplaces
Autorzy:
Dugheri, Stefano
Bonari, Alessandro
Pompilio, Ilenia
Boccalon, Pierpaolo
Tognoni, Daniela
Cecchi, Michele
Ughi, Massimo
Mucci, Nicola
Arcangeli, Giulio
Powiązania:
https://bibliotekanauki.pl/articles/2162575.pdf
Data publikacji:
2018-12-18
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
occupational exposure
LC-MS/MS
ICP-MS
urine
antineoplastic drugs
wipe test
Opis:
Background Cytotoxic antineoplastic drugs (ADs), widely used in treating cancer, are considered hazardous in the workplace and thus require safe handling practices. An analytical protocol for environmental and biological AD monitoring in the healthcare environment has been developed, since Europe lacks clear guidelines and regulations for cytostatic preparation and handling. Material and Methods Liquid chromatography-tandem mass spectrometry (LC-MS/MS) was used for measuring contemporaneously 20 multi-class cytostatic compounds and urinary α-fluoro-β-alanine, whereas platinum was detected by inductively coupled plasma mass spectrometry (ICP-MS). Sampling procedures and analytical conditions were optimized and the assays were validated. Environmental AD monitoring data, collected in 2009–2017, for a total of 3749 wipe tests and 57 720 determinations, was evaluated. Results The proportion of positive samples gradually decreased from 11.7% in 2010 to 1% in 2017, however, 2266 determinations were positive. No urine sample had detectable concentrations of any of the 4 drugs considered (0/398 samples). Conclusions These improvements are so large that the key role played by the new, more stringent rules for preparing and administering ADs is evident. Hence, the analytical method involving multi-element determinations allows for a more thorough and complete investigation into the AD contamination of work environments. Med Pr 2018;69(6):589–604
Źródło:
Medycyna Pracy; 2018, 69, 6; 589-604
0465-5893
2353-1339
Pojawia się w:
Medycyna Pracy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Dissipation of methomyl residues in tomato fruits, soil and water using LC-MS/MS
Autorzy:
El-Hefny, D.
Abdallah, I.
Helmy, R.
Mahmoud, H.
Powiązania:
https://bibliotekanauki.pl/articles/2084623.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
dissipation
LC-MS/MS
methomyl
tomato
QuEChERS
Opis:
Tomato is an economically important vegetable crop which is attacked heavily by insect pests leading to reduction of yield and quality of the fruits. Field experiments were carried out to investigate the dissipation of methomyl (a common insecticide) used mainly on tomato fruits. LC-MS/MS coupled with the QuEChERS method were used for the determination of methomyl. The results showed that the recovery using matrix-matched standards ranged from 87.8 to 101.3%, with relative standard deviation of 2.5 to 7.5%. Kinetics equation, Log R = log R0 – 0.434 Kt, was used to calculate the rate of degradation in tomato, soil and water. Residue half-life calculated using kinetic rate ranged from 1.95 to 1.63 days in tomato and soil, respectively. From the results it was concluded that tomato fruits can be safely harvested for consumption after 15 days of application based on estimated preharvest interval (PHI). It is advisable to re-estimate the PHI regularly owing to data from the EU and Codex.
Źródło:
Journal of Plant Protection Research; 2019, 59, 3; 355-361
1427-4345
Pojawia się w:
Journal of Plant Protection Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
New Rapid Analysis of two Classes of Pesticides in Food Wastewater by Quechers-Liquid Chromatography/Mass Spectrometry
Autorzy:
Łozowicka, B.
Kaczyński, P.
Szabuńko, J.
Ignatowicz, K.
Warentowicz, D.
Łozowicki, J.
Powiązania:
https://bibliotekanauki.pl/articles/123585.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Inżynierii Ekologicznej
Tematy:
wastewater
azole
neonicotinoids
QuEChERS
LC-MS/MS
Opis:
The rapid analytical method was developed in response to increasing concern over the environmental impact of azoles (sterol biosynthesis inhibitors) and neonicotinoids (nicotinic acetylcholine receptor site). These chemicals are commonly used to protect fruit and vegetables crops against fungi and pests. Seven insecticides and twenty one fungicides commonly occurring in food industrial wastewater have been determined. For this purpose, active substances from two new pesticide classes were extracted and isolated by QuEChERS by addition of acetonitrile, buffering salts and chitin as a clean-up sorbent. The novelty of this procedure was one step sample preparation including extraction and removing of co-extracts in short time. Instrumental analysis was conducted by liquid chromatography coupled with mass spectrometry using multiple reaction monitoring. The limits of detection ranged from 0.002 to 0.005 μg·L-1 with satisfactory accuracy and precision The recoveries for the pesticides ranged from 81–103%, with high repeatability (n = 3, RSD ≤ 9%) and low LOQs (0.01 μg·L-1). Matrix effects calculated were less than 12% for all analyses. The method was applied to routine analysis of food industrial wastewater. Concerning the results, total pesticide levels in most cases were below 1 μg·L -1. The most significant pesticides in terms of concentration and frequency of detection were acetamiprid (0.07 μg· L-1); tebuconazole (1.2 μg· L-1) and thiacloprid (0.04 μg·L-1).
Źródło:
Journal of Ecological Engineering; 2016, 17, 3; 97-105
2299-8993
Pojawia się w:
Journal of Ecological Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Occurrence of mycotoxins in talkan: a cereal-based food traditional for Turkic population
Autorzy:
Tattibayeva, D.
Nebot, C.
Miranda J.M.
Abuova, A.B.
Kizatova, M.Z.
Vazquez, B.
Powiązania:
https://bibliotekanauki.pl/articles/2087741.pdf
Data publikacji:
2018
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
food-contamination
corn
fungi
HPLC-MS/MS
Kazakhstan
Źródło:
Polish Journal of Veterinary Sciences; 2018, 21, 2; 333-341
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Acrylamide content in cigarette mainstream smoke and estimation of exposure to acrylamide from tobacco smoke in Poland
Autorzy:
Mojska, Hanna
Gielecińska, Iwona
Cendrowski, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/989240.pdf
Data publikacji:
2016
Wydawca:
Instytut Medycyny Wsi
Tematy:
acrylamide
cigarette mainstream smoke
lc-ms/ms
exposure assessment
Opis:
Introduction and objective. Acrylamide is a “probably human carcinogen” monomer that can form in heated starchy food as a result of a reaction between asparagine and reducing sugars via Maillard reaction. The main source of acrylamide in human diet are potato products, cereal products and coffee. Tobacco smoke may be another significant source of exposure to acrylamide. The aim of our study was to determine acrylamide content in cigarettes available on the Polish market and to estimate the exposure to acrylamide originating from tobacco smoke in smokers in Poland. Materials and methods. The material was cigarettes of the top five brands bought in Poland and tobacco from non-smoked cigarettes. Acrylamide content in cigarettes mainstream smoke was determined by LC-MS/MS. Exposure assessment was carried out using analytical data of acrylamide content in cigarettes and the mean quantity of cigarettes smoked daily by smokers in Poland, assuming body weight at 70 kg. Results. The mean content of acrylamide was 679.3 ng/cigarette (range: 455.0 – 822.5 ng/cigarette). The content of acrylamide was evidenced to correlate positively with total particulate matter (TPM) content in cigarettes. The estimated average exposure to acrylamide from tobacco smoke in adult smokers in Poland is 0.17 μg/kg b.w./day. Conclusions. Our results demonstrate that tobacco smoke is a significant source of acrylamide and total exposure to acrylamide in the population of smokers, on average, is higher by more than 50% in comparison with non-smokers. Our estimation of exposure to acrylamide from tobacco smoke is the first estimation taking into account the actual determined acrylamide content in the cigarettes available on the market.
Źródło:
Annals of Agricultural and Environmental Medicine; 2016, 23, 3
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Investigation of Colour Centres in SrLaAlO$\text{}_{4}$ and SrLaGaO$\text{}_{4}$ Single Crystals
Autorzy:
Ubizskii, S. B.
Savytskii, D.I.
Olijnyk, V. Ya.
Matkovskii, A. O.
Gloubokov, A.
Pajączkowska, A.
Powiązania:
https://bibliotekanauki.pl/articles/1964350.pdf
Data publikacji:
1997-07
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
61.82.Ms
Opis:
Absorption spectra of SrLaAlO$\text{}_{4}$ and SrLaGaO$\text{}_{4}$ single crystals are investigated as well as their changes after irradiation by γ-quanta ($\text{}^{60}$Co source). Both crystals reveal a similar behaviour that is caused, as it seems, by the same nature of colour centres in them. The conclusion that oxygen defects as well as Fe impurities play a significant role in the colour centres formation in these crystals.
Źródło:
Acta Physica Polonica A; 1997, 92, 1; 163-168
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Integracja systemu MS-WIM w środowisku LabView
MS-WIM system integration in LabView
Autorzy:
Piwowar, P.
Powiązania:
https://bibliotekanauki.pl/articles/155886.pdf
Data publikacji:
2007
Wydawca:
Stowarzyszenie Inżynierów i Techników Mechaników Polskich
Tematy:
MS-WIM
LabView
Opis:
W pracy zaprezentowano nadrzędny system zbierania i przetwarzania danych pomiarowych przeznaczony do współpracy z wieloczujnikowym systemem WIM. System zbudowany został w oparciu o komputer klasy PC i kartę PCI RS232/8 firmy National Instrument zwiększającą o osiem liczbę portów RS232 komputera oraz oprogramowanie w postaci programu MS-WIM v.1.0, które steruje systemami podrzędnymi oraz odbieraniem i przetwarzaniem danych pomiarowych. Oprogramowanie zostało stworzone przy wykorzystaniu środowiska LabView.
The paper presents a master system of data acquisition and data processing, designed for cooperation with Multisensor WIM System. The system consists of the PC computer, PCI RS232/8 National Instrument board and application software MS-WIM v.1.0. The application software was created with using LabView graphical software system.
Źródło:
Pomiary Automatyka Kontrola; 2007, R. 53, nr 9 bis, 9 bis; 713-716
0032-4140
Pojawia się w:
Pomiary Automatyka Kontrola
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Study of Anticoagulant Dabigatran by Analytical Instrumentation
Autorzy:
Patel, B.
Ram, P.
Khatri, T.
Ram, V
Dave, P.
Powiązania:
https://bibliotekanauki.pl/articles/412564.pdf
Data publikacji:
2014
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Dabigatran
UPLC/MS/MS
zeta potential
FTIR
UV-NIR
Thermal analysis
Opis:
Dabigatran with IUPAC name 3-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-methyl-1H-benzoimidazole-5-carbonyl}-pyridin-2-yl-amino)-propionic acid, which can be used to prevent strokes in those with atrial fibrillation due to causes other than heart valve disease, and at least one additional risk factor for stroke (congestive heart failure, hypertension, age, diabetes, and prior stroke), with molecular formula C34H41N7H5 was studied in detail for functional group analysis with FTIR, characteristic absorbance by UV-NIR, thermal behavior by TGA-DTA-DSC, particle size and stability of the molecule with Nano particle size analyzer. The structure was confirmed by LC-MS/MS with ESI probe and mass was found in aggregation with the reported standard values. The purity of drug was determined by Prep. HPLC analysis. FTIR analysis showed the characteristic peak of carboxylic acid, UV-NIR analysis showed that the λmax was 224 nm with methanol as a diluent, the compound was found stable in the thermal analysis, the average particle size was found to be 25.2 nm, Z-average as 0.2 nm and zeta potential as -67.6 mv hence showed excellent stability in the zeta potential analysis as per ASTM standards D4187-82, American Society of Testing and Materials, 1985.
Źródło:
International Letters of Chemistry, Physics and Astronomy; 2014, 11, 3; 233-242
2299-3843
Pojawia się w:
International Letters of Chemistry, Physics and Astronomy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Eschatologia w teorii i w praktyce. Próba prezentacji zagadnienia na podstawie wybranych tekstów ks. Jana Berthiera MS
Eschatology in Theory and in Practice. An Attempt to Present the Issue Based on Selected Texts of Fr. Jan Berthier MS
Autorzy:
Kulik, Bogdan
Powiązania:
https://bibliotekanauki.pl/articles/28903305.pdf
Data publikacji:
2021
Wydawca:
Uniwersytet Papieski Jana Pawła II w Krakowie
Tematy:
eschatologia
ars moriendi
ks. Jan Berthier MS
eschatology
Fr. John Berthier MS
Opis:
Artykuł jest próbą prezentacji dwóch tekstów ks. Jana Berthiera MS – założyciela Misjonarzy Świętej Rodziny: traktatu o rzeczach ostatecznych i praktycznej metody towarzyszenia umierającym. Celem artykułu nie jest krytyczna analiza eschatologii Berthiera, lecz wykazanie na jej przykładzie konieczności łączenia akademickiego wykładu eschatologii (teoria) z duszpasterstwem (praktyka). Dokonana prezentacja prowadzi do trzech wniosków: 1) nieustająca konieczność obecności eschatologii w nauczaniu i praktyce Kościoła; 2) potrzeba aktualizowania rozumienia jej treści i sposobu przekazu; 3) waga spójności teorii i praktyki eschatologicznej.
The article is an attempt to present two texts by Fr. Jan Berthier MS – Founder of the Missionaries of the Holy Family: a treaty on the last things and a practical method of accompanying the dying. The aim of this article is not to critically analyze Berthier’s eschatology, but to demonstrate on its example the necessity of combining academic lecture of eschatology (theory) with pastoral care (practice). The presentation leads to three conclusions: 1) the continuing need for presence of eschatology in the teaching and practice of the Church; 2) the need to update the understanding of its content and method of its communication; 3) the importance of coherence of eschatological theory and practice.
Źródło:
Polonia Sacra; 2021, 25, 3; 149-167
1428-5673
Pojawia się w:
Polonia Sacra
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pozostałości pestycydów w próbkach wielkopolskich wód powierzchniowych pobieranych na terenach intensywnie użytkowanych rolniczo (2006-2007)
Pesticide residues in surface water samples collected in areas of intensive agricultural practice of the Wielkopolska Province (2006-2007)
Autorzy:
Dróżdżyński, D.
Folkman, W.
Kowalska, J.
Powiązania:
https://bibliotekanauki.pl/articles/127551.pdf
Data publikacji:
2009
Wydawca:
Towarzystwo Chemii i Inżynierii Ekologicznej
Tematy:
wody powierzchniowe
pozostałości pestycydów
RP-UPLC-MS/MS
surface waters
pesticide residues
Opis:
Próbki wód powierzchniowych zlokalizowanych na terenach intensywnej gospodarki rolnej województwa wielkopolskiego były pobierane w 2006 i 2007 roku. Ogółem 55 próbek (30 i 25 odpowiednio w latach 2006 i 2007) pozyskano z jezior (15 w 2006 roku, 10 w 2007 roku), rzek (po 9 próbek w każdym z lat) oraz stawów (po 6 próbek w każdym z lat). Badaniami objęto 42 herbicydy, insektycydy i fungicydy popularnie stosowane w ochronie roślin. Spośród wszystkich pobranych próbek wód 43 (78,2%) miało pozostałości środków ochrony roślin używanych w intensywnej produkcji rolnej. Wszystkie wybrane do badań pestycydy były ekstrahowane z próbek wód z wykorzystaniem ekstrakcji do fazy stałej (węgiel aktywowany), a następnie oznaczane metodą chromatografii cieczowej z tandemowym detektorem masowym (RP-UPLC-MS/MS). Najczęściej w analizowanych próbkach wykrywano pozostałości atrazyny (60,0%), desetyloatrazyny (56,4%), karbendazymu (45,4%), symazyny (36,4%), desisopropyloatrazyny (34,5%), izoproturonu (29,1%) i etofumesatu (21,8%). Ogółem, pozostałości 29 z 42 poszukiwanych pestycydów zostały znalezione, jednakże ich stężenia były zazwyczaj na bardzo niskim poziomie. Dolna granica oznaczalności została wyznaczona dla poszczególnych pestycydów w przedziale od 0,01 do 0,05 µg/dm3. Największa znaleziona pozostałość pochodziła od metabolitu triazyn desetyloatrazyny (0,55 µg/dm3, staw, maj 2007). Wszystkie próbki wody pozyskane ze stawów były zanieczyszczone pozostałościami poszukiwanych pestycydów i zarazem na najwyższym poziomie ilościowym. W próbkach wód pozyskanych z rzek pozostałości pestycydów były oznaczane tylko na bardzo niskim poziomie (0,01÷0,04 µg/dm3).
Samples of surface waters of intensively exploited arable lands in Wielkopolska province of Poland were collected in 2006 and 2007. Totally, 55 samples (30 and 25 in 2006 and 2007, respectively) from lakes (15 and 10 in 2006 and 2007, respectively), rivers (9 and 9 in 2006 and 2007, respectively) and ponds (6 and 6 in 2006 and 2007, respectively) were collected. The studies included 42 herbicides (and their metabolites), insecticides and fungicides popularly used in plants protection. All selected pesticides were extracted from water samples by means of solid phase extraction (SPE, carbon black) followed by reverse phase ultra performance liquid chromatography analysis with quadrupole mass detection (RP-UPLC-MS/MS). Of all samples, 43 (78.2%) were contaminated with residues of plant protection products used in intensive plant production. Contamination with atrazine (60.0%), atrazine-desethyl (56.4%), carbendazim (45.4%), simazine (36.4%), atrazine-deisopropyl (34.5%), isoproturon (29.1%), and ethofumesate (21.8%) of the samples were mostly detected. Totally, twenty nine of forty two studied pesticides were found however, concentrations of their residues were usually very low. The limit of quantification for determined pesticides were between 0.01 to 0.05 µg/dm3. The highest concentration was quantified for the triazine metabolite atrazine-desethyl (0.55 µg/dm3, pond, May 2007). All the pond water samples were contaminated by pesticide residues and the highest concentration was found in these samples. In the river water samples pesticide residues were detected only occasionally and on the very low level (0.01÷0.04 µg/dm3).
Źródło:
Proceedings of ECOpole; 2009, 3, 2; 445-449
1898-617X
2084-4557
Pojawia się w:
Proceedings of ECOpole
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Characterization of Triterpene Saponin Composition of White, Yellow and Red Beetroot (Beta vulgaris L.)
Autorzy:
Spórna-Kucab, Aneta
Tekieli, Anna
Skalicka-Woźniak, Krystyna
Grzegorczyk, Agnieszka
Świergosz, Tomasz
Wybraniec, Sławomir
Powiązania:
https://bibliotekanauki.pl/articles/2051041.pdf
Data publikacji:
2022-06-06
Wydawca:
Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie
Tematy:
betavulgarosides
Beta vulgaris L
food composition
LC-MS/MS
oleanolic acid
saponins
Opis:
Beta vulgaris L. is an important source of bioactive saponins – a group of secondary metabolites – that have spurred a growing interest due to their health-promoting properties. This study aimed to gain information on triterpene saponin profile of the peel and flesh of white, yellow and red beet of six cultivars – Snow Ball, Boldor, Ceryl, Chrobry, Forono and Tytus – harvested in Poland, in the same region. Twenty four saponins with oleanolic acid, hederagenin, akebonoic acid and gypsogenin as aglycons were identified and quantified by liquid chromatography/tandem mass spectrometry (LC-ESI-MS/MS). Among them, betavulgaroside I, II, III and IV were the major compounds, but the quantitative profile of saponins was found to be dependent on beet cultivar and root part, respectively. The highest content of saponins was found in the peel of yellow B. vulgaris Boldor (20812 mg/kg fresh weight, fw), while the lowest saponin content was determined in the flesh of white B. vulgaris Snow Ball (497 mg/kg fw). In addition, the total saponin content in peel and flesh in yellow beet (26054 mg/kg fw) was much higher than the total content in peel and flesh in red beet Tytus (8364 mg/kg fw) and white beet Snow Ball (1204 mg/kg fw). This is the first report on the profile of saponins in white and yellow beets.
Źródło:
Polish Journal of Food and Nutrition Sciences; 2022, 72, 2; 159-170
1230-0322
2083-6007
Pojawia się w:
Polish Journal of Food and Nutrition Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Progressive forms of multiple sclerosis: disease-modifying therapy review
Autorzy:
Sapko, Klaudia
Szczepańska-Szerej, Anna
Jamroz-Wiśniewska, Anna
Kulczyński, Marcin
Marciniec, Michał
Rejdak, Konrad
Powiązania:
https://bibliotekanauki.pl/articles/1167060.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Disease-modifying drugs
Multiple sclerosis
New therapy
Primary-progressive MS
Secondary-progressive MS
Opis:
Multiple sclerosis (MS) is a demyelinating, inflammatory, autoimmune disease of the central nervous system which affects most commonly young adults. It has wide spectrum of clinical and radiological presentations with relapses or steady progression. Recent years have brought new reports on the pathogenesis of MS. This systematized the current MS classification and created new parameters describing the course of the disease, such as activity and progression. Attention has been paid to the need for new drugs that focus on the treatment of progressive MS. Until now, the primary and secondary progressive MS have been somewhat forgotten, and most of modifying-disease drugs have been registered in the treatment of relapsing-remitting subtype. In recent years, not only new drug has been registered for the treatment of progressive MS (ocrelizumab) and another one is planned to be approved soon (siponimod), but also indications of old medicines (interferon-beta1b, cladribine, mitoxantrone, cyclophosphamide, azathioprine) have been extended. Despite intensive development, there is still a great need to seek new drugs that will stop the progression of disability in MS patients.
Źródło:
World Scientific News; 2018, 105; 157-167
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Puffed cereals with added chamomile - quantitative analysis of polyphenols and optimization of their extraction method
Autorzy:
Blicharski, Tomasz
Oniszczuk, Anna
Olech, Marta
Oniszczuk, Tomasz
Wójtowicz, Agnieszka
Krawczyk, Wojciech
Nowak, Renata
Powiązania:
https://bibliotekanauki.pl/articles/986662.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
matricaria chamomilla
functional food
polyphenolic antioxidants
lc-esi-ms/ms analysis
extraction methods
Opis:
Introduction. Functional food plays an important role in the prevention, management and treatment of chronic diseases. One of the most interesting techniques of functional food production is extrusion-cooking. Functional foods may include such items as puffed cereals, breads and beverages that are fortified with vitamins, some nutraceuticals and herbs. Due to its pharmacological activity, chamomile flowers are the most popular components added to functional food. Objective. Quantitative analysis of polyphenolic antioxidants, as well as comparison of various methods for the extraction of phenolic compounds from corn puffed cereals, puffed cereals with an addition of chamomile (3, 5, 10 and 20%) and from Chamomillae anthodium. Materials and Methods. Two modern extraction methods – ultrasound assisted extraction (UAE) at 40 °C and 60 °C, as well as accelerated solvent extraction (ASE) at 100 °C and 120 °C were used for the isolation of polyphenols from functional food. Analysis of flavonoids and phenolic acids was carried out using reversed-phase high-performance liquid chromatography and electrospray ionization mass spectrometry (LC-ESI-MS/MS). Results and Conclusions. For most of the analyzed compounds, the highest yields were obtained by ultrasound assisted extraction. The highest temperature during the ultrasonification process (60 °C) increased the efficiency of extraction, without degradation of polyphenols. UAE easily arrives at extraction equilibrium and therefore permits shorter periods of time, reducing the energy input. Furthermore, UAE meets the requirements of ‘Green Chemistry’.
Źródło:
Annals of Agricultural and Environmental Medicine; 2017, 24, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Influence of selected soil parameters on amino acid profile in Stellaria media
Autorzy:
M. Dziągwa-Becker, Magdalena
Kalitowska, Olga
A. Oleszek, Wiesław
Powiązania:
https://bibliotekanauki.pl/articles/2168198.pdf
Data publikacji:
2016-12-30
Wydawca:
Instytut Uprawy Nawożenia i Gleboznawstwa – Państwowy Instytut Badawczy
Tematy:
free amino acids
LC-MS/MS
soil organic matter
soil quality
common chickweed
Opis:
The study investigates the relationship between soilsthat vary for different basic physicochemical parameters (pH,phosphorus and potassium content, granulometric compositionand soil organic matter content) and the free amino acids content of Stellaria media. According to some research, plant aminoacid profile is a good indicator of the condition of the soils onwhich plants are grown. In this experiment, a rapid and sensitiveliquid chromatography coupled with tandem mass spectrometry(LC-MS/MS) method was used for the identification and quantification of nineteen proteinogenic amino acids in Stellaria mediasamples, which is a very common weed found worldwide. Significant linkage was found between the soil parameters and Stellariamedia amino acid content. Garden soil is the most favourable soilfor amino acid content. Glutamine, glutamic and aspartic acid arethe most abundant amino acids in Stellaria media grown on allthree tested soils.
Źródło:
Polish Journal of Agronomy; 2016, 27; 32-37
2081-2787
Pojawia się w:
Polish Journal of Agronomy
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 347

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