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Tytuł:
A levels of endogenous gonadal hormones and their relationship with selected coronary artery disease risk factors among young women post myocardial infarction
Autorzy:
Ablewska, Urszula
Jankowski, Krzysztof
Rzewuska, Ewa
Liszewska-Pfejfer, Danuta
Hryniewiecki, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1039893.pdf
Data publikacji:
2011
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
myocardial infarction
gonadal hormones
risk factors
young women
Opis:
In recent decades a significant raise in the incidence of myocardial infarction among young women has been recorded. It is presumed that, apart from the classical risk factors, other reasons exist for premature atherosclerosis in young women, related to the homeostasis of gonadal hormones. The aim of the study was to analyze the levels of gonadal hormones (estradiol, progesterone, follicle-stimulating hormone, luteinizing hormone, testosterone and dehydroepiandrosterone) measured in the luteal phase, in 65 normally menstruating women post myocardial infarction (MI) and to investigate a possible relationship between the hormone profile and selected coronary artery disease (CAD) risk factors. The levels of gonadal hormones: estradiol, progesterone, follicle-stimulating hormone, luteinizing hormone, testosterone and dehydroepiandrosterone were measured in the luteal phase. All examined women had normal mean levels of gonadal hormones. In the post MI patients leading a sedentary life style, a significantly lower mean progesterone concentration was observed (16.29 ± 9.11 versus 29.43 ± 21.14 nmol/l, p < 0.05) and significantly higher mean testosterone concentration (2.34 ± 0.98 versus 1.76 ± 1.09 nmol/l, p < 0.05) when compared to patients from the same group, but leading a more active life. In obese post MI women (BMI ≥ 30 kg/m2) a lower mean concentration of progesterone was detected (18.02 ± 8.12 versus 26.16 ± 14.72 nmol/l, p < 0.05), than in slimmer patients from the same group. In post MI women with a positive family history for CAD, a significantly higher mean concentration of testosterone was detected (2.31 ± 1.22 versus 1.67 ± 0.74 nmol/l, p < 0.05) than in patients with no family history. The results suggest a correlation between levels of gonadal hormones and classical CAD risk factors.
Źródło:
Acta Biochimica Polonica; 2011, 58, 3; 385-389
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Changes in the concentrations of thyroid hormones in dairy sheep
Autorzy:
Flis, Z.
Molik, E.
Powiązania:
https://bibliotekanauki.pl/articles/2119543.pdf
Data publikacji:
2021
Wydawca:
Polskie Towarzystwo Zootechniczne
Tematy:
sheep
thyroid hormones
lactation
milk
Opis:
The aim of the research was to determine the changes in the concentrations of thyroid hormones (T3 and T4) in sheep during lactation. The experiment was conducted on 20 Polish Longwool ewes. Milking was begun after the lambs were weaned, on the 57th day of lactation. Sheep were milked twice a day (8:00 a.m. and 6:00 p.m.) until dry. The milk yield of each ewe was checked every 10 days. For determination of thyroid hormones, blood was collected every 28 days beginning at sunset, every 20 minutes for 6 hours. The average milk yield of the sheep was determined based on the individual yields on test days. The highest (P ≤ 0,01) milk yield was obtained in the first month of milking, i.e. April (0,48 ± 0,018 l). Milk yield decreased as lactation progressed. The concentration of hormone T3 was significantly higher (P ≤ 0,01) in the first and third months of lactation (0,72 ± 0,02 ng/ml in April and 0,74 ± 0,02 ng/ml in June) than in September (0,55 ± 0,01 ng/ml). The T3 concentration decreased in successive months of lactation. In contrast, the concentration of the T4 hormone increased with the progression of lactation. Significantly (P ≤ 0,01) the lowest concentration of T4 was found in the first and second month of milking (51,7 ± 9,8 ng/ml, 48,8 ± 7,4 ng/ml). The highest T4 concentration in lactating sheep was noted in August (60,55 ± 10 ng/ml). The research showed that the secretion of T3 decreases with milk yield, while secretion of T4 shows an upward trend as lactation progresses. Therefore thyroid hormones modulate secretion of milk in sheep.
Źródło:
Roczniki Naukowe Polskiego Towarzystwa Zootechnicznego; 2021, 17, 1; 7-12
1733-7305
Pojawia się w:
Roczniki Naukowe Polskiego Towarzystwa Zootechnicznego
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Czy cechy osobowości i aktualny status hormonalny determinuje w przyszłości osiągnięcia sportowe łuczników i łuczniczek?
Are personality traits and current hormonal status determine future achievements of male and female archers?
Autorzy:
Obmiński, Zbigniew
Mroczkowska, Helena
Powiązania:
https://bibliotekanauki.pl/articles/2152202.pdf
Data publikacji:
2020-10-20
Wydawca:
Fundacja Edukacji Medycznej, Promocji Zdrowia, Sztuki i Kultury Ars Medica
Tematy:
archery
hormones
gender
sport achievements
łucznictwo
osobowość
płeć
osiągnięcia sportowe
Opis:
Background. The intent of our study was to seek possible relationships between selected personality traits and the current hormonal status in blood (cortisol and testosterone) among young male and female archers of similar average age (~16.4 years) and their sport achievements (SA) in a future. Material and methods. Morning blood cortisol (C) and testosterone (T) levels and selected personality traits were determined in19 male and 19 female archers. 16 years after the study the data were analyzed with regards to the (SA) expressed by numerical rating and achieved until the end of their career. Results. There were no significant differences between the males and females in scores of examined: trait anxiety (An), neuroticism (Ne), extraversion (Ex), briskness (Br), perseveration (Pe), sensory sensitivity (SS), emotional reactivity (ER), endurance (En), activity (Ac) and C. In females An, Ne and ER correlated positively SA. In males SA was independent on any personality trait, while T correlated negatively with An and Ne and positively with briskness. Conclusions. In young archers there is no significant sex-related differences in personality traits, but this thesis is of limited value because of small sample size. Assuming that in young athletes the personality is not very stable, there are recommended short-term prognosis regarding sport achievements.
Wstęp. Celem naszego badania było poszukiwanie możliwych relacji między wybranymi cechami osobowości a obecnym stanem hormonalnym we krwi (kortyzol i testosteron) wśród młodych łuczników i łuczniczek płci w podobnym średnim wieku (~ 16,4 lat) i ich osiągnięciach sportowych (SA) w przyszłości. Materiał i metody. Poranne stężenie kortyzolu we krwi (C) i testosteronu (T) oraz wybrane cechy osobowości określono u 19 łuczników i 19 łuczniczek. 16 lat po tym badaniu zebrane wcześniej dane zostały przeanalizowane w odniesieniu do (SA) wyrażonych ocenę numeryczną do zakończenia kariery. Wyniki. Nie było istotnych między-płciowych w wynikach: lęku jako cechy (An), neurotyczności (Ne), ekstrawersji (Ex), żwawości (Br), perseweratywności (Pe), wrażliwości sensorycznej (SS), reaktywności emocjonalnej (ER), wytrzymałości (En), aktywności (Ac) i C. U kobiet An, Ne i ER dodatnio korelują z SA. U mężczyzn SA nie zależał od jakiejkolwiek cechy osobowości, podczas gdy T ujemnie korelował z An i Ne a dodatnio z Br. Wnioski. U młodych łuczników nie ma znaczących różnic w cechach osobowości związanych z płcią, ale ta teza ma ograniczoną wartość ze względu na małą wielkość próbki. Zakładając, że u młodych sportowców osobowość nie jest zbyt stabilna, zaleca się krótkoterminowe rokowanie dotyczące osiągnięć sportowych w przyszłości.
Źródło:
Polish Journal of Sports Medicine; 2020, 36(2); 57-64
1232-406X
2084-431X
Pojawia się w:
Polish Journal of Sports Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Dualizm poznawczy czyli sztuka interpretacji architektury [obiekt architektoniczny – dzieło sztuki]
Cognitive Dualism, or the Art of Architecture Interpretation [Architectural Object – Work of Art]
Autorzy:
Słuchocka, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/2058455.pdf
Data publikacji:
2020
Wydawca:
Politechnika Krakowska im. Tadeusza Kościuszki. Wydział Architektury. Instytut Projektowania Architektonicznego. Zakład Architektury Mieszkaniowej i Kompozycji Architektonicznej
Tematy:
hormony architektury
kontrola poznawcza
przestrzeń egzystencjalna
hormones of architecture
cognitive control
existential space
Opis:
Poszukiwanie metod badawczych w porównawczych sferach złożoności psychiki kobiecej ze skomplikowaną strukturą architektury ma na celu optymalizację procesów projektowych w oczekiwaniach skutkujących przestrzenią kształtowaną na miarę wymagań, wygodną, bezpieczną, kroczącą z duchem czasu, ikoniczną, a przy tym wyrażającą się niekwestionowanym pięknem. Weryfikacja podobieństw zachodzi na dwóch płaszczyznach, oceny funkcji i oceny formy, przy uwzględnieniu czynników hormonalnych. W tym kontekście upodmiotowienie architektury do roli kobiety pozwala w jak najszerszym zakresie korzystać z operowania emocjami i zmysłami, stanowiącymi nieprzebyte źródło rodzących się doznań, często fenomenologicznie budujących nasze doświadczenie. Bogactwo charakterologiczne obu, wsparte rzemiosłem budowlanym, rzetelnością wykonawczą, technologią, a nade wszystko wiedzą, wyobraźnią i świadomością architekta, wskazuje na możliwość pojawienia się elementów kontroli poznawczej, co implikuje zwiększenie wpływu na jakość kształtowanej wokół nas rzeczywistości.
Looking for research methods in the comparative spheres of female psychological complexity and complex architectural structure is aimed at optimizing the design processes and expected to result in a space that is shaped to satisfy requirements, comfortable, safe, up– to–date, iconic and at the same time emanates unquestionable beauty. Verification of similarities is made on two levels: evaluation of form and evaluation of function, with taking hormonal factors into account. In this context, subjectification of architecture to the woman’s role allows one to make use, to the widest possible extent, of emotions and senses being an endless source of emerging sensations that often phenomenologically build our experience. Characterological richness of both, supported with construction craftsmanship, reliability of execution, technology, but more importantly by knowledge, imagination and awareness of an architect, points to the possibility of occurrence of cognitive control elements, which implies increased impact on the quality of the reality shaped around us.
Źródło:
Pretekst; 2020, 10; 38--45
2449-5247
Pojawia się w:
Pretekst
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effects of creatine hydrochloride supplementation on physical performance and hormonal changes in soldiers
Autorzy:
Tayebi, Mohammad Milad
Yousefpour, Mitra
Ghahari, Laya
Powiązania:
https://bibliotekanauki.pl/articles/1932984.pdf
Data publikacji:
2021-05-19
Wydawca:
PPHU Projack Jacek Wąsik
Tematy:
creatine
performance
HCl
hormones
Opis:
Purpose: The aim of this study was to examine the effects of 2 weeks of creatine hydrochloride (CrHCl) supplementation on physical performance and hormonal changes in army soldiers. Materials: Eighteen male army soldiers were randomly assigned in a double-blind fashion to either a CrHCl (n=9) or placebo (Pl) (n=9) groups. CrHCl group costumed 3g of creatine per day, whereas Pl group was given dextrose. Before and after supplementation period, the subjects performed a battery of performance tests including one repletion maximum (1RM) of bench press and back squat, vertical jump (VJ) and Wingate anaerobic test. In addition, blood samples were obtained to determine changes in testosterone and cortisol concentrations per and post supplementation. Results: There were significant increases in VJ, peak and mean power, and 1RM back squat test following the 2 weeks of CrHCl supplementation (p < 0.05) without any significant change for the Pl group. In addition significant changes were observed in testosterone and cortisol concentrations from before to after supplementation in CrHCl group (p < 0.05) and compared with Pl group (p=0.001). Conclusions: In conclusion, the present study indicates that CrHCl supplementation can improve VJ, power performance, 1RM back squat and hormonal changes in army soldiers.
Źródło:
Physical Activity Review; 2021, 1, 9; 93-99
2300-5076
Pojawia się w:
Physical Activity Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effects of rooting hormones on the juvenile stem cuttings of Annona muricata Linn. (Annonaceae)
Autorzy:
Dada, C. A.
Kayode, J.
Arowosegbe, S.
Powiązania:
https://bibliotekanauki.pl/articles/1077472.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Annona muricata
Juvenile Stem Cuttings
Medicinal plant
Rooting Hormones
Opis:
Annona muricata is a recognized medicinal plant species. Despite its usefulness, adequate attention has not been given to its propagation and cultivation. Therefore, this study investigates the effect of some rooting hormones on juvenile stem cuttings of Annona muricata. Uniform, healthy, single node leafy stem cuttings were obtained from eighty (80) uniformly growing seedlings. The cuttings were treated with 1mg/ml of Indole Acetic Acid (IAA), 1 mg/ml of Indole Butyric Acid (IBA), coconut water and distilled water as control, using the quick dip method. The percentage survival of the cuttings, percentage of die back, number of new roots formed per cutting, length of new roots formed, and number of new shoot were assessed after 60 days. Results obtained revealed that the species responded differently to the four treatments. Coconut water had the highest survivor percentage (100%) and IBA had the lowest (25%). Coconut water had the highest mean number of roots (5.25) and IBA had the least (1.75), but there was no significant difference between the values obtained from IBA and distilled water. IAA had the highest mean value (1.80) for new shoots, while IBA had the least value and there was no significant difference between the values obtained from coconut water and distilled water. Significant differences, however, did abound in the root length. Coconut water had the highest mean root length value (4.70 cm), followed by distilled water (1.95 cm), while IBA had 1.55 cm and IAA had the least value (0.80 cm). Thus the use of coconut water might enhance the development of stem cuttings of Annona muricata.
Źródło:
World News of Natural Sciences; 2019, 23; 336-342
2543-5426
Pojawia się w:
World News of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Estrogen removal from wastewater
Usuwanie estrogenu ze ścieków
Autorzy:
Grdulska, Agnieszka
Kowalik, Robert
Powiązania:
https://bibliotekanauki.pl/articles/402106.pdf
Data publikacji:
2020
Wydawca:
Politechnika Świętokrzyska w Kielcach. Wydawnictwo PŚw
Tematy:
estrogens
hormones in sewage
methods of estrogen removal from sewage
sewage treatment
estrogeny
hormony w ściekach
metody usuwania estrogenów ze ścieków
oczyszczanie ścieków
Opis:
Currently, a significant problem of water and sewage management is the presence of human hormones, especially estrogens and progestagens, consumed by women in contraceptives and then excreted from the body. While other drugs are used by a small part of the population and rather sporadically, hormonal contraception is used by a large number of women, which contributes to their high concentration in sewage. Even relatively low estrogen concentrations (compared to other drugs) can have harmful effects on the body, disturbing the hormonal balance and leading to various endocrine disorders. In this paper the types of individual estrogen groups were characterized. Next, different methods of their removal from wastewater were presented. The parameters of estrogen removal efficiency depend on which parameters. Next, the effectiveness of each method was compared, also taking into account economic aspects. The work was summarized with appropriate conclusions.
Obecnie istotnym problemem gospodarki wodno-ściekowej jest obecność w ściekach ludzkich hormonów, a zwłaszcza estrogenów i progestagenów, spożywanych przez kobiety w preparatach antykoncepcyjnych i wydalanych następnie z organizmu. O ile po inne leki sięga niewielka część populacji i to raczej sporadycznie, o tyle z antykoncepcji hormonalnej korzysta olbrzymia liczba kobiet, co przyczynia się do wysokiego ich stężenia w ściekach. Nawet stosunkowo małe stężenie estrogenów (w porównaniu z innymi lekami) może mieć szkodliwe skutki dla organizmu, zaburzając w nim równowagę hormonalną i prowadząc do różnych schorzeń endokrynologicznych. W pracy scharakteryzowano rodzaje poszczególnych grup estrogenów. Następnie przedstawiono różne metody ich usuwania ze ścieków. Przedstawiono, od jakich parametrów zależy efektywność usuwania estrogenów. Następnie porównano skuteczność każdej z metod, biorąc również pod uwagę aspekty ekonomiczne. Pracę podsumowano odpowiednimi wnioskami.
Źródło:
Structure and Environment; 2020, 12, 3; 133-141
2081-1500
Pojawia się w:
Structure and Environment
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of the Psychological and Hormonal Parameters in Paragliding
Autorzy:
Çalık, Deniz Sinem
Gürsoy, Recep
Saruhan, Ercan
Powiązania:
https://bibliotekanauki.pl/articles/1627250.pdf
Data publikacji:
2021-09-10
Wydawca:
Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
Tematy:
paragliding
hormones
risk
anxiety
Opis:
Background. Paragliding is an extreme sport performed by gliding from a mountain at high altitude into the air. The authors aimed to determine the differences between the levels of adrenaline, cortisol, and insulin before and after the flight of tandem pilots and passengers flying for the first time, and to determine the relationship between these hormones and death anxiety and risk-taking levels. Materials and methods. The study included 12 experienced male pilots and 15 male passengers flying for the first time. Heart rate and blood pressure were measured after the participants had filled in Personal Information Form, DOSPERT Risk-Taking Scale and Death Anxiety Scale before the flight. Blood samples were taken before and after the flight to determine adrenaline, cortisol, and insulin levels. Results. Adrenaline and cortisol levels, as well as heart rate, increased significantly after the flight, while insulin levels decreased significantly in the passenger group (p < 0.05). There were no statistically significant differences in the pilot group. Conclusions. The experience factor plays an important role in the positive effect of paragliding flight on cortisol, adrenaline, insulin, and various physiological parameters, as well as mediates the adaptation of the organism to unusual situations. The human organism adapts physiologically and hormonally to the flying action. One of the striking results of the study was that cortisol levels were at the upper limit of normal values in the passenger group after the flight.
Źródło:
Central European Journal of Sport Sciences and Medicine; 2021, 34, 2; 15-23
2300-9705
2353-2807
Pojawia się w:
Central European Journal of Sport Sciences and Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of the relationship between subclinical hypothyroidism and metabolic syndrome components among workers
Autorzy:
Cheserek, Maureen
Wu, Guirong
Shen, Liye
Shi, Yonghui
Le, Guowei
Powiązania:
https://bibliotekanauki.pl/articles/2178818.pdf
Data publikacji:
2014-05-17
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
cardiovascular risks
metabolic syndrome
occupation
subclinical hypothyroidism
thyroid hormones
university workers
Opis:
Objectives: Both hyperthyroidism and overt hypothyroidism are associated with increased prevalence of metabolic syndrome and its components, while data on subclinical hypothyroidism is currently limited especially in working populations. The aim of this study was to examine the association between subclinical hypothyroidism and metabolic syndrome components in workers; and to evaluate whether there are differences by sex and occupation. Material and Methods: A total of 1150 university employees (male - 792, female - 358) aged 30-60 years who came for an annual medical check-up were studied. Anthropometric measurements were taken, and blood pressure, fasting plasma glucose (FPG), lipid profiles, thyroid stimulating hormone (TSH), free thyroxin (FT4) and free triiodothyronine (FT3) levels were measured. Results: After adjustment for age and body mass index (BMI), TSH was positively associated with increased triglyceride (TG) levels (β = 0.108, p = 0.020) and FPG (β = 0.130, p = 0.006) in subclinical hypothyroid male workers. However, TSH was not associated (p > 0.05) with any component of metabolic syndrome (MS) in the euthyroid group. In females, TSH was not correlated with MS components in both euthyroid and subclinical hypothyroid groups. Furthermore, comparison by occupation showed higher TSH in subclinical hypothyroid male workers employed in administration (5.23±0.52 mU/l) than those working as academics (5.12±0.52 mU/l), which resulted in elevated systolic and diastolic blood pressure, FPG, total cholesterol, TG and high density lipoprotein cholesterol. In females, BMI, systolic and diastolic blood pressure, TG and FPG were significantly (p < 0.05) higher in subclinical hypothyroid administrators than those in academics. Conclusions: Subclinical hypothyroidism was associated with metabolic syndrome components in male workers and not in females. Administration workers showed increased metabolic risks compared to academics. The findings suggest that the assessment of thyroid function in individuals with metabolic syndrome in the workplace may be favorable especially among men.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2014, 27, 2; 175-187
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Expression of abscisic and gibberellic acid signalling factors in Fagus sylvatica L. seeds during dormancy breaking and germination
Autorzy:
Staszak, A.M.
Pers-Kamczyc, E.
Klupczynska, E.A.
Pawłowski, T.A.
Powiązania:
https://bibliotekanauki.pl/articles/2077752.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Instytut Dendrologii PAN
Tematy:
ABI5
RGL2
14-3-3
plant hormones
tree
Opis:
European beech seeds are characterised by deep physiological dormancy and to germinate, they require several weeks of stratification at 3°C. Seed dormancy is under hormonal regulation, but the de- tails of how hormones regulate deep dormancy in trees remain not yet well elucidated. We hypothesised that the mechanism of seed dormancy breaking is differentially regulated according to depth of dormancy. Expression of ABI5 and 14-3-3, members of the abscisic acid pathway, and RGL2, a member of gibberel- lic acid pathways, were examined at the protein and mRNA levels during dormancy alleviation of beech seeds. Unlike in non-deep dormant seeds, ABI5, 14-3-3 and RGL2 were present during nearly all periods of cold stratification in beech seeds, but during dormancy breaking and germination these proteins nearly disappeared. Relative abundances of ABI5 and 14-3-3 transcripts were the highest in dormant dry seeds, and during stratification it decreased gradually. We suppose that during stratification, de novo translation of proteins on the basis of deposited mRNA occurred. On the base of our research we can conclude that the seed dormancy breaking mechanism differs according to seed’s dormancy depth
Źródło:
Dendrobiology; 2019, 81; 22-30
1641-1307
Pojawia się w:
Dendrobiology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Fizjologiczne reakcje zwierząt na penetrację turystyczną zajmowanej przez nie przestrzeni
Physiological reaction of animals on touristic penetration of their habitat
Autorzy:
Juszko, S.
Powiązania:
https://bibliotekanauki.pl/articles/95906.pdf
Data publikacji:
2016
Wydawca:
Fundacja Ekonomistów Środowiska i Zasobów Naturalnych
Tematy:
turystyka na obszarach naturalnych
hormon stresu
fotodetekcja
wpływ turystyki na zwierzęta
tourism in natural areas
stress hormones
photodetection
impact of tourism on animals
Opis:
In many studies on tourism in the environmentally valuable areas the advantages for both human health and the budgets of local governments and its residents themselves are emphasized, as well as for increasing knowledge and awareness of tourists through personal contact with nature. However, while we admire the colorful folders, describing the charms of experiencing the nature and plan a similar trip, we should remember that our vacation, especially when spend in environmentally valuable areas require some kind of responsibility and discipline and can not be completely carefree. Since the beginning of the 90s the growth of various forms of tourism is observed in Poland, both: mass and individual. People are increasingly looking for personal contact with nature, to rest from a daily activities, to regenerate and regain health, to acquire knowledge but also to find a unique and sometimes strong experiences to boast with them in front of friends. For a human those things are undoubtedly something positive, but the presence of a human in a space inhabited by wild animals may cause negative reactions, because a man is a potent inducer of stress for the animals. We know about the destructive effects of stress on human health from the daily press or from TV, and it seems that it may have just the same effect on life of animals. Current research techniques allow us to study stress levels in the bodies of wild animals by non-invasively, by analyzing the concentration of glucocorticoids (ie. Stress hormone) in their feces. This method was used for both research on non-predatory influence of predators on the prey and the impact of human on the wild animals. Studies have confirmed that human is a strong stress factor for animals (stressor), which the animals are trying to avoid if possible. It was also stated that he higher levels of stress hormones in animals in places and time related with greater touristic penetration. The negative impact of long-lasting stressor is the greater when rarer species are treated exposed on it. That is why the organization and planning of tourism in environmentally valuable areas should also consider its impact on local animals populations.
Źródło:
Ekonomia i Środowisko; 2016, 1; 223-235
0867-8898
Pojawia się w:
Ekonomia i Środowisko
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hormony steroidowe, leki przeciwzapalne, pigułki antykoncepcyjne. związki i ludzie : notatki historyczne (część I i II)
Hormones, antiinflammatory drugs, contraceptive pills. compounds and the people : historic notes (part I and II)
Autorzy:
Wicha, Jerzy
Powiązania:
https://bibliotekanauki.pl/articles/1409983.pdf
Data publikacji:
2021
Wydawca:
Polskie Towarzystwo Chemiczne
Tematy:
notatki historyczne
steroidy
hormony płciowe
kortykosteroidy
pigułki antykoncepcyjne
transformacje steroidowe
synteza totalna
historic notes
steroids
sex hormones
corticosteroids
contraceptive pills
steroid transformations
total synthesis
Opis:
A short historical outlook of steroid hormones isolation, structure elucidation and hormonal drugs development following by a survey of contraceptive therapeutics syntheses and advancements is given. Structural evolution of the first pills, “the pill”, to the presently used oral contraceptives for women is scrutinized. Comments on activities of selected major researchers in the field: Josef Fried, Russell E. Marker, Arthur J. Birch, Carl Djerassi, Georgy G. Pincus, M. C. Chang, John Rock, Igor V. Torgov, Zoltan G. Hajos and Herchel Smith from the personal prospect are presented. Steroid sex hormones, estrogens (female), androgens (male) and gestagens (progesterone, pregnancy hormone) were isolated and identified as chemical entities in 20-tiest and 30-ties of the 20th century. Development of partial synthesis of basic hormones from cholesterol made possible the initial steroid drugs production: Testosterone propionate and 17a-Methyltestosterone (Ciba) as well as Proviron, Progynon, Proluton (Schering AG). In 1940th and 1950th corticosteroids were isolated and recognized as “magic” anti-inflammatory and antiarthritic drugs. Growing demand for antiarthritic drugs in 1950th stimulated search for new corticosteroid analogues and new steroid row materials. Exploration of Mexican plant Dioscorea “cabeza” by Synthex SA provided economical starting material, diosgenin, and opened the new prospects for hormonal drug research and the production. Subsequently, highly active corticosteroid analogues were developed by several pharmaceutical companies and 19-norprogesterone analogues of high gestagenic activity were synthesized - Norethisterone (Synthex) and Norethyndrel (Searle). Complex studies on the application of Norethyndrel as oral contraceptive for women were carried out in the Worcester Foundation for Experimental Biology. In 1959 the first drug “the pill”, which was developed on the grounds of Searls’ Norethyndrel - Enovid was registered by Food and Drug Administration in the USA. Shortly after that Norlutin, based upon Synthex’s Norethisterone, had also been approved for application. Commercial success of “the pill”, Enovid and Norlutin, triggered a broad research aimed at the partial synthesis and application of related progesterone analogues. In the end of 1950th and the beginning of 1960th the total synthesis of estrogens and 19-norsteroids gained practical importance. On these grounds Norgestrel and its active enancjomer Levonorgestrel were developed and commercialized by Wyeth Laboratories Inc. in the USA as the first contraceptive products by total synthesis. Starting from 1970th medicinal applications of corticosteroids gradually diminished, whereas growing attention was given to the development of hormonal contraceptives suitable for general application. Several synthetic modifications of Norethisterone and Levonorgestrel were developed and produced in a large scale. Another class of oral contraceptives stem from the steroid total synthesis developed in the Russell Uclaf laboratories. Structurally these compounds are characterized by 19-norsteroid core and the presence of bulky substituent at the position 11ß, as 4-(N,N-dimethylamino)phenyl- in Mifepristone (RU 486). The synthesis of 19-norpregnane derivatives bearing at the position 11ß various large aromatic or alphatic groups, which currently is receiving a great deal of attention, is considered.
Źródło:
Wiadomości Chemiczne; 2021, 75, 5-6; 677-753
0043-5104
2300-0295
Pojawia się w:
Wiadomości Chemiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Microbiome impact on metabolism and function of sex, thyroid, growth and parathyroid hormones
Autorzy:
Kunc, Michał
Gabrych, Anna
Witkowski, Jacek
Powiązania:
https://bibliotekanauki.pl/articles/1038795.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
microbiome
lipopolysaccharide
estrogens
thyroid hormones
growth hormone
Opis:
Commensal bacteria and their genes associated with host are known as microbiome. In recent years, microbial influence on host endocrine system has been under detailed investigation. The role of microbiome in the pathogenesis of insulin resistance and obesity, the function of hypothalamic-pituitary-adrenal axis and secretion of hormones regulating appetite is well described in world literature. In this article we discuss poorly reviewed issues: the microbiome role in modulation of non-peptide (sex and thyroid) and peptide (growth hormone and parathyroid hormone) functions. Understanding complex bidirectional relations between host endocrine system and bacteria is of fundamental importance to understanding microbial impact on host reproduction, risk of endocrine-related cancers, pathogenesis of non-thyroidal illness syndrome, growth failure in children and hormonal changes during chronic kidney disease. This article also highlights effects of dietary compounds on microbiome composition and bacterial enzymes activity, and thus host hormonal status.
Źródło:
Acta Biochimica Polonica; 2016, 63, 2; 189-201
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Możliwości wykorzystania nanofiltracji do usuwania estrogenów z roztworów wodnych
Removal of estrogens by nanofiltration
Autorzy:
Dudziak, M.
Bodzek, M.
Powiązania:
https://bibliotekanauki.pl/articles/236784.pdf
Data publikacji:
2005
Wydawca:
Polskie Zrzeszenie Inżynierów i Techników Sanitarnych
Tematy:
środowisko wodne
hormony płciowe
estrogeny
oczyszczanie wody
oczyszczanie ścieków
nanofiltracja
water environment
hormones
estrogens
water treatment
wastewater treatment
nanofiltration
Opis:
Obecnie obserwuje się nowe zagrożenia wynikające z obecności w środowisku wodnym substancji biologicznie aktywnych, które mogą zakłócać funkcje endokrynologiczne organizmu (EDCs - Endocrine Disrupting Compunds). Do tej grupy związków zalicza się żeńskie hormony płciowe (estron, 17(beta)-estradiol i estriol), których obecność w środowisku wodnym była do niedawna ignorowana. Ponadto w wodach zidentyfikowano szereg odpowiedników naturalnych estrogenów, stosowanych w medycynie i w weterynarii (17(alfa)-etinylestradiol, mestranol i dietylostilbestrol). Nieodpowiednio oczyszczone ścieki powodują obciążenie środowiska wodnego tymi mikrozanieczyszczeniami, co może prowadzić do nieodwracalnych zmian. Jako jeden z kierunków rozwoju technologii oczyszczania wody i ścieków proponuje się stosowanie technik membranowych. W pracy przedstawiono podstawowe parametry procesu nanofiltracji oraz jego zastosowanie do usuwania naturalnych i syntetycznych estrogenów z roztworów wodnych. Omówione w pracy osiągnięcia i problemy wskazują na potrzebę prowadzenia badań w tym kierunku, co może przyczynić się do lepszego poznania procesu nanofiltracji oraz do jego szybszego wdrożenia na skalę techniczną.
In recent years new environmental threats arising from the presence of some endocrine disrupting compounds (EDCs) in aquatic environment have been reported. Female sex hormones (estrone, 17 (beta)-estradiol and estriol) are frequently regarded as the main species belonging to the EDCs group. Their presence in the water environment has been ignored until recently. These days also various equivalent compounds to natural estrogens that are widely used in medicine and veterinary medicine (17 (alfa)-ethinylestradiol, mestranol and diethylstilbestrol) are being detected there. An inadequate treatment of wastewaters carrying micropollutants of that type may produce contamination of the aquatic environment, as well as some irreversible changes. Membrane techniques are regarded as an alternative to conventional water and wastewater treatment. In the study reported on in this paper consideration was given to the nanofiltration process, its parameters and potentiality for the removal of natural and synthetic estrogens from aqueous solutions. The results obtained, along with those reported by other investigators, substantiate the need of further research in this field in order to gain a better understanding of the nanofiltration process and speed up its application on a technical scale.
Źródło:
Ochrona Środowiska; 2005, R. 27, nr 2, 2; 9-12
1230-6169
Pojawia się w:
Ochrona Środowiska
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Oznaczanie hormonów steroidowych w materiale biologicznym
Autorzy:
Kotłowska, A.
Szulfer, J.
Kamysz, W.
Powiązania:
https://bibliotekanauki.pl/articles/274307.pdf
Data publikacji:
2010
Wydawca:
Roble
Tematy:
oznaczanie hormonów steroidowych
hormony steroidowe
steroid hormones marking
Źródło:
LAB Laboratoria, Aparatura, Badania; 2010, 15, 4; 20-23
1427-5619
Pojawia się w:
LAB Laboratoria, Aparatura, Badania
Dostawca treści:
Biblioteka Nauki
Artykuł
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