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Wyświetlanie 1-15 z 69
Tytuł:
13C-urea breath test for detection of Helicobacter pylori and its correlation with endoscopic and histologic findings
Autorzy:
Hilker, E
Domschke, W.
Stoll, R.
Powiązania:
https://bibliotekanauki.pl/articles/71128.pdf
Data publikacji:
1996
Wydawca:
Polskie Towarzystwo Fizjologiczne
Tematy:
gastritis
gastric ulcer
infection
mucosa
endoscopical finding
duodenal ulcer
urea breath test
Helicobacter pylori
gastric carcinoma
lymphatic tissue
ulcer
stable isotope
histological finding
stomach
urease
malignant lymphoma
Źródło:
Journal of Physiology and Pharmacology; 1996, 47, 1
0867-5910
Pojawia się w:
Journal of Physiology and Pharmacology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analiza cech histoklinicznych w grupie dzieci z infekcją Helicobacter pylori potwierdzoną w raportach histopatologicznych
Autorzy:
Taran, Katarzyna
Prasał, Katarzyna
Toporowska-Kowalska, Ewa
Wąsowska-Królikowska, Krystyna
Kobos, Józef
Powiązania:
https://bibliotekanauki.pl/articles/553060.pdf
Data publikacji:
2013
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
Helicobacter pylori
zapalenie błony śluzowej żołądka
dzieci
Źródło:
Family Medicine & Primary Care Review; 2013, 2; 186-187
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antigen-specific lymphocyte proliferation as a marker of immune response in guinea pigs with sustained Helicobacter pylori infection
Autorzy:
Miszczyk, Eliza
Walencka, Maria
Rudnicka, Karolina
Matusiak, Agnieszka
Rudnicka, Wiesława
Chmiela, Magdalena
Powiązania:
https://bibliotekanauki.pl/articles/1039292.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Helicobacter pylori
T cells
proliferation
guinea pigs
Opis:
Helicobacter pylori (H. pylori) bacteria are human pathogens causing symptomatic gastritis, peptic ulcer or gastric cancer. Little is known about the kinetics of immune responses in H. pylori infected patients because the initial moment of infection has not been identified. Various animal models are used to investigate the immune processes related to H. pylori infection. In this study we checked whether H. pylori infection in guinea pigs, mimicking natural H. pylori infection in humans, resulted in the development of specific immune responses to H. pylori antigens by measuring the proliferation of lymphocytes localized in mesenteric lymph nodes, spleen and peripheral blood. The maturity of macrophages and cytokines, delivered by monocyte-macrophage lineage or lymphocytes, were considered as mediators, which might influence the lymphocyte blastogenic response. The obtained results showed the activation of T cells localized in mesenteric lymph nodes by H. pylori antigens in H. pylori infected guinea pigs four weeks postinfection. The blastogenic activity of lymphocytes was shaped by their interaction with antigen presenting cells, which were present in the cell cultures during the whole culture period. Moreover, the balance between cytokines derived from adherent leukocytes including interleukin 8 - IL-8 as well as interferon gamma - IFN-γ, and transforming growth factor beta - TGF-β delivered by lymphocytes, was probably important for the successful proliferation of lymphocytes. The H. pylori specific lymphocytes were not propagated in peripheral blood and spleen of H. pylori infected animals. The modulation of immunocompetent cells by H. pylori antigens or their different distribution cannot be excluded.
Źródło:
Acta Biochimica Polonica; 2014, 61, 2; 295-303
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antimicrobial Activity of the Essential oil of Thymus capitatus against Helicobacter pylori
Autorzy:
güvenir, meryem
Hanoglu, Azmi
Hanoglu, Duygu
Suer, Kaya
Baser, Husnu Can
Ozkum Yavuz, Dudu
Sanlıdag, Tamer
Powiązania:
https://bibliotekanauki.pl/articles/895252.pdf
Data publikacji:
2020-02-29
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
helicobacter pylori
Thymus capitatus
in vi
essential oil
Opis:
Helicobacter pylori (H.pylori) is an infective agent and the main resourceful factor of chronic, active ot type B gastritis, peptic and duodenal ulcer, gastric carcinoma and mucosa-associated lymphoid tumors. Nowadays, pharmological treatment of H. pylori infections attract attention beside antibiotic treatment. The aim of this study is to analyse the chemical composition of the essential oils of Thymus capitatus and the antimicrobial activity against H. pylori. Aerial parts of wild growing plant materials were collected during flowering stage from three different locations. Essential oil composition analyses were performed simultaneously by GC-FID and GC-MS systems. The antimicrobial activity of the essential oil were tested by broth dilution method. The thymol percentage was determined as more than half of the essential oil composition of Thymus capitatus-Yedidalga (51.9%) and Thymus capitatus –Yıldırım (57.1%); however, the composition of thymol was 47.2% followed by 15.1% (p-cymene), 10.0% (-terpinene) and 5.7% (carvacrol) for Thymus capitatus-Boğaz/Girne.The essential oil from Thymus capitatus- Boğaz/Girne showed the lowest MIC and MBC values and the strongest bactericidal activity against H. pylori compared to the other tested essential oils. Bactericidal efficacy of essential oil of Thymus capitatus on H. pylori could have been affected due to the varied rates of major compounds. Thymus capitatus essential oil could be an alternative way for the treatment of H. pylori infections.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2020, 77, 1; 155-160
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Apoptosis in the gastric mucosa: molecular mechanisms, basic and clinical implications
Autorzy:
Szabo, I.
Tarnawski, A.S.
Powiązania:
https://bibliotekanauki.pl/articles/69195.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Fizjologiczne
Tematy:
plasma membrane
molecular mechanism
epithelial cell
gastric gland
gastric mucosa
mucosal surface
stomach
apoptosis
Helicobacter pylori
clinical implication
Źródło:
Journal of Physiology and Pharmacology; 2000, 51, 1
0867-5910
Pojawia się w:
Journal of Physiology and Pharmacology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Application of Helicobacter pylori antigen test to evaluate gastric mucosa specimens
Autorzy:
Namiot, A.
Leszczyńska, K.
Namiot, D.B.
Chilewicz, M.
Bucki, R.
Kemona, A
Namiot, Z.
Powiązania:
https://bibliotekanauki.pl/articles/1916576.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
Helicobacter pylori antigens
immunoassay
gastric mucosa
Opis:
Purpose: To investigate, whether the test documenting the presence of Helicobacter pylori (H. pylori) antigens in the gastric mucosa may be used as diagnostic test. Materials and methods: Mucosal specimens taken from eighty-three patients during gastroscopic examination were subjected to rapid urease test (CLO test), histology, and H. pylori culture. The same biopsy specimens that had been evaluated in the CLO test or collected into the transport medium for bacterial culture were used to detect H. pylori antigens. An amplified immunoassay for the detection of H. pylori antigens in stool was used for gastric mucosa specimens. The sensitivity and specificity of the H. pylori antigen test were evaluated in relation to the results of each verifying test (CLO test, histology, culture) separately and to all 3 tests analysed together. Results: The sensitivity and specificity of the H. pylori antigen test in relation to the CLO test, histological examination, and H. pylori culture were 85.4% and 90.5%, 76.1% and 83.4%, and 90.7% and 90.0% for specimens taken for the CLO test and 90.0% and 82.0%, 78.0% and 81.0%, and 93.0% and 88.0% for specimens taken for bacterial culture, respectively. The sensitivity and specificity of the antigen test in relation to all 3 verifying tests analysed together were 91.3% and 97.3% for specimens taken for the CLO test, and 91.7% and 97.1% for specimens taken for bacterial culture, respectively. Conclusions: H. pylori antigen test in gastric mucosa specimens may be a sufficiently reliable source of information about stomach infection.
Źródło:
Progress in Health Sciences; 2014, 4, 2; 52-57
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Badania przezywalnosci Heliobacter pylori w mleku
Heliobacter pylori survival in milk
Autorzy:
Kafel, S
Pogorzelska, E.
Lekowska-Kochaniak, A.
Powiązania:
https://bibliotekanauki.pl/articles/877132.pdf
Data publikacji:
1993
Wydawca:
Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
Tematy:
przezywalnosc bakterii
Heliobacter pylori
mikrobiologia zywnosci
choroby bakteryjne
choroby czlowieka
zywnosc
choroby przewodu pokarmowego
mleko
bakterie
zywienie czlowieka
bacterial survival
Helicobacter pylori
food microbiology
bacterial disease
human disease
food
alimentary tract disease
milk
bacteria
human nutrition
Opis:
W związku z brakiem doniesień na temat występowania Heliobacter pylori w żywności oraz źródeł infekcji i sposobu przenoszenia tych bakterii na ludzi przeprowadzono badania nadprzeżywalnością H. pylori w mleku przechowywanym w temperaturze pokojowej oraz w lodówce w temperaturze 5-TC.
The survival of microaerophilic bacteria Heliobacter pylori (Hp) isolated from gastric mucosa was studied in 2 ml and 10 ml samples of milk contaminated with a suspension of these bacteria in 20% glucose solution. Milk was kept at 5-7°C temperature in refrigerator and at room temperature. Hp was found in samples kept at 5-TC during 3 days. On the other hand, Hp was not found after 24-hours keeping at room temperatura.
Źródło:
Roczniki Państwowego Zakładu Higieny; 1993, 44, 2-3; 171-173
0035-7715
Pojawia się w:
Roczniki Państwowego Zakładu Higieny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Can urea breath test (UBT) replace rapid urea test (RUT)?
Autorzy:
Nawacki, Łukasz
Czyż, Agata
Bryk, Piotr
Kozieł, Dorota
Stępień, Renata
Głuszek, Stanisław
Powiązania:
https://bibliotekanauki.pl/articles/1392890.pdf
Data publikacji:
2018
Wydawca:
Index Copernicus International
Tematy:
Helicobacter pylori
urea breath test
rapid urea test
gastric cancer
Opis:
Background: Helicobacter pylori (Hp) is classified by the International Agency for Research on Cancer (IARC) as a Group 1 carcinogen. Its influence on the carcinogenesis of gastric cancer has been confirmed in many research studies. The conclusion is obvious - early detection and eradication of Hp can prevent the development of the disease. Methods: The objective of the study was to analyze the clinical and practical value of Carbon-13 urea breath test (UBT) in patients hospitalized due to pain complaints in the upper abdomen and dyspeptic symptoms. Fifty patients were enrolled in the study. Each patient underwent urea breath test according to the instruction included by the producer. Thereafter, each patient included in the study group was subjected to endoscopy of the upper gastrointestinal tract with the biopsy of the mucosa to determine the urease activity with rapid urease test (RUT). Results: In the study group, 14 patients (28%) achieved a positive urease test result which was confirmed in RUT. Four (8%) patients, despite a positive breath test, did not have a positive result in urease activity test from gastric mucosa. In 2 cases (4%) despite negative result of UBT, urease activity was confirmed in gastroscopic sections. The remaining 30 patients (60%) had a negative result in both studies. Conclusions: The limited availability of the gold standard for diagnostics of upper gastrointestinal tract diseases (gastroscopy) is the basis for the search for new methods of detection of Helicobacter pylori infections. The urea breath test is a method of high sensitivity and specificity. The positive result of urea breath test may be the basis for inclusion of eradication therapy.
Źródło:
Polish Journal of Surgery; 2018, 90, 5; 44-48
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Comparison of aspartate proteinase activity of Candida albicans strains isolated from children with and without Helicobacter pylori
Autorzy:
Rozga, A.
Kurnatowski, M.
Wasowska-Krolikowska, K.
Powiązania:
https://bibliotekanauki.pl/articles/841572.pdf
Data publikacji:
1998
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
aspartate proteinase
gastrointestinal tract
child
Candida albicans
Helicobacter pylori
Źródło:
Annals of Parasitology; 1998, 44, 3
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Conflicting results of non-invasive methods for detection of Helicobacter pylori infection in children with celiac disease - a preliminary study
Autorzy:
Józefczuk, Jan
Mądry, Edyta
Nowak, Jan
Walkowiak, Marek
Łochocka, Klaudia
Banasiewicz, Tomasz
Pławski, Andrzej
Kwiecień, Jarosław
Walkowiak, Jarosław
Powiązania:
https://bibliotekanauki.pl/articles/1038852.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Helicobacter pylori
celiac disease
fecal test
breath test
urea
Opis:
Background: There are no data addressing the usefulness of non-invasive tests for the detection of Helicobacter pylori (HP) infection in celiac disease (CD). Aim: The aim of this study was to compare two most sensitive and specific tests - urea breath test (UBT) and fecal antigen test (FAT) in HP diagnosis in CD patients. Materials and Methods: The study comprised of 76 CD patients, 49 healthy subjects (HS) and 35 patients who underwent differential diagnosis due to abdominal pain (AP patients). The presence of HP infection was evaluated using the 13C isotope-labeled UBT and FAT (ELISA). Results: HP infection was diagnosed based on UBT and FAT in 8 (16.3%) and 7 (14.3%) HS, and in 8 (10.5%) CD patients and 12 (34.3%) AP patients, respectively, using both tests. The prevalence of conflicting results in comparison with positive results (obtained with any of the two tests) was distinctly higher (54.5%) in CD group than in other subjects (23.3%); however, due to low HP prevalence, it did not reach the level of significance (p<0.1759). Conclusion: CD may increase the risk of divergent results of non-invasive tests used for the detection of HP infection in children. Since UBT is the most reliable test, we suggest its standard use as a method of choice in pediatric CD - at least until new evidence emerges supporting a different approach.
Źródło:
Acta Biochimica Polonica; 2016, 63, 1; 127-130
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cost-effectiveness of H. pylori eradication
Autorzy:
Roesch, W
Powiązania:
https://bibliotekanauki.pl/articles/69557.pdf
Data publikacji:
1996
Wydawca:
Polskie Towarzystwo Fizjologiczne
Tematy:
peptic ulcer
antimicrobial agent
infection
antibiotic
duodenal ulcer
therapy
antisecretory drug
disorder
eradication
Helicobacter pylori
Źródło:
Journal of Physiology and Pharmacology; 1996, 47, 1
0867-5910
Pojawia się w:
Journal of Physiology and Pharmacology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Critical evaluation of the treatment of peptic ulcer diseases associated with Helicobacter pylori infection
Autorzy:
Gabryelewicz, A
Powiązania:
https://bibliotekanauki.pl/articles/69294.pdf
Data publikacji:
1996
Wydawca:
Polskie Towarzystwo Fizjologiczne
Tematy:
gastric ulcer
tetracycline
pathogenesis
infection
gastric acid secretion
in vivo
intragastric pH
tinidazole
bismuth
in vitro
Helicobacter pylori
peptic ulcer
histamine
metronidazole
clarithromycin
antibiotic
antimicrobial drug
amoxicillin
eradication
Źródło:
Journal of Physiology and Pharmacology; 1996, 47, 1
0867-5910
Pojawia się w:
Journal of Physiology and Pharmacology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Current status of Helicobacter pylori associated human gastric cancer and the therapeutic approaches – A Review
Autorzy:
Pal, Partha
Powiązania:
https://bibliotekanauki.pl/articles/1189965.pdf
Data publikacji:
2016
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Helicobacter pylori
Gastric carcinoma
Peptic ulcers
Antibiotic treatment
Opis:
In the recent years one of the common causes of cancer related deaths in humans is associated with the development of gastric carcinoma leading to gastric cancer. It had long before reported that the potent agent that is intimately related with the gastric cancer is the infection of the bacterium Helicobacter pylori (H. pylori). H. pylori infection in humans is characterised by the development of acute peptic ulcers which creates a lots of gastroenterological symptoms. Co-existence of H. pylori in the human gastric environment is well adapted by the pathogen by evading the immune responses of the host. Gastric biopsy in patients suffering from H. pylori infection reported the development of gastric lesions having the chance to proceed towards development gastric cancer. Recently it was reported that eradication of the H. pylori colonization is not possible even after continued current antibiotic treatment over long periods and even combined regimes are unsuccessful.Moreover alterations of the genetic background of the host gastric cells were also reported along with infection of H. pylori, the primary concern for the evolution of the genetically transformed cells which is the hallmark for the development of malignancy. Clinical studies have reported the limited efficacy in decreasing the incidence of gastric carcinoma even after the eradication therapy has been completed for the bacterial colonization. Research based on the biopsy specimens obtained from conventional gastric endoscopy of affected patients has revealed some genetic or epigenetic alterations in the gastric mucosa. The cause of concern to human life lies in the fact that the number of sporadic cases of primary or metachronous gastric carcinoma has increased after successful eradication.The purpose of the present review is to assess the current status of the research based on the concept of development of gastric carcinoma in association with H. pylori infection in humans and to throw some light in the remedial measures against the pathogen which is a chronic burden in the well-being of the human society.
Źródło:
World Scientific News; 2016, 52; 162-180
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 69

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