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    Wyświetlanie 1-4 z 4
    Tytuł:
    Association between intestinal and antioxidant barriers in children with cancer
    Autorzy:
    Stachowicz-Stencel, Teresa
    Synakiewicz, Anna
    Owczarzak, Anna
    Sliwinska, Aleksandra
    Lysiak-Szydlowska, Wieslawa
    Balcerska, Anna
    Powiązania:
    https://bibliotekanauki.pl/articles/1039739.pdf
    Data publikacji:
    2012
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    childhood cancer
    intestinal permeability
    oxidative stress
    Opis:
    Objective: Reactive oxygen species (ROS) play a role in cancerogenesis processing and damage tissues. Furthermore, oncological treatment may impair proper function of the gut barrier. The aim of this study was to measure intestinal permeability in children in clinical remission for solid tumours and to search for a possible relationship between free radicals and the intestinal barrier. No such investigation in children has been reported so far. Research Methods and Procedures: The prospective study consisted of 19 paediatric patients with cancer after completion of chemotherapy. 32 healthy children from the outpatients clinics were recruited for measurement of intestinal permeability and antioxidant barrier as a control group. Intestinal permeability was assessed by measurement of urinary lactulose and mannitol after oral challenge. Antioxidant enzymes: superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in erythrocytes were assessed. Ischemia modified albumin (IMA) concentration was measured in serum. Results: Cancer patients excreted less mannitol and more lactulose versus controls. The ratio of lactulose to mannitol was significantly higher in oncological children vs control (mean 0.188 and 0.0453, respectively, p=0.0006,). Significantly higher IMA level in the oncological group vs control was noted (mean 123.8 and 87.3 U/ml, respectively, p=0.0037). No correlation between intestinal permeability and oxidative stress barrier was found. Conclusions: Our data shows that intestinal barrier is damaged in paediatric cancer patients after chemotherapy. IMA is believed to play a protective role in the defence against tissue damage. No correlation was found between these two barriers.
    Źródło:
    Acta Biochimica Polonica; 2012, 59, 2; 237-242
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Psychosocial functioning of childhood cancer survivors living in rural areas
    Autorzy:
    Samardakiewicz, M
    Kowalczyk, J.R.
    Powiązania:
    https://bibliotekanauki.pl/articles/49655.pdf
    Data publikacji:
    2007
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    patient
    psychosocial functioning
    rural area
    childhood cancer
    cancer
    cognitive functioning
    Opis:
    High-dose chemotherapy currently used in the treatment of children with cancer may induce late effects on psychosocial and cognitive functioning in some of them. The aim of the study was to evaluate psychosocial functioning of childhood cancer survivors living in rural regions. In total, 29 children entered the study. The children were diagnosed as having cancer between 1993-1995 in a single centre. Each patient was examined 5 years after the completion of cancer therapy. The children had been diagnosed with leukemia and lymphoma (72.4%), and solid tumours. Self-report questionnaires, as well as standardized psychological test (WISC-R, WAIS-R-PL) were performed for the evaluation of psychosocial and cognitive functioning of the patients. Most of the studied cancer survivors living in rural areas did not reveal diffi culties with cognitive and psychosocial functioning. In some patients, however, we observed more diffi culties in verbal tasks and existing major learning diffi culties. Cancer survivors living in rural areas in our region may be more unprivileged due to poor additional supporting services.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2007, 14, 2
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Cognitive and language-based disabilities of children diagnosed with cancer
    Poznawcze i językowe zaburzenia u dzieci z rozpoznaniem raka
    Autorzy:
    Alvarez-Benito, Gloria
    Fernandez-Corbacho, Anali
    Herrero Machancoses, Francisco
    del Carmen Fonseca-Mora, Maria
    Powiązania:
    https://bibliotekanauki.pl/articles/1401440.pdf
    Data publikacji:
    2019-06-25
    Wydawca:
    Państwowa Uczelnia Zawodowa we Włocławku
    Tematy:
    childhood cancer
    language disabilities
    cognitive evaluation
    discourse analysis
    communication abilities
    language use
    rak dziecięcy
    zaburzenia językowe
    ocena poznawcza
    analiza dyskursu
    zdolności komunikacyjne
    użycie języka
    Opis:
    The survival rate of children suffering from cancer has increased, but collateral effects have been observed. A mixed-method was used to evaluate cancer children’s language and cognitive abilities. Variables such as IQ and verbal comprehension, perceptual reasoning, working memory and processing speed were tested. Further-more, a semiguided 30-minute-long conversation on everyday matters was used for linguistic evaluation. Results confirm that language problems were present at phonological, lexical-semantic, structural or syntactic, pragmatic and non-verbal levels.
    Wskaźnik przeżywalności dzieci cierpiących na raka wzrósł, ale zaobserwowano efekty dodatkowe. Metoda mieszana została wykorzystana do oceny języka i zdolności poznawczych dzieci chorych na raka. Przetestowano zmienne, takie jak IQ i rozumienie werbalne, rozumowanie percepcyjne, pamięć roboczą i szybkość przetwarzania. Ponadto do oceny językowej użyto 30-minutowej, częściowo sterowanej rozmowy na temat spraw codziennych. Wyniki potwierdzają, że problemy językowe były obecne na poziomach fonologicznych, leksykalno-semantycznych, strukturalnych lub syntaktycznych, pragmatycznych i niewerbalnych.
    Źródło:
    Zeszyty Naukowe Zbliżenia Cywilizacyjne; 2019, 15, 2; 12-37
    1896-4087
    Pojawia się w:
    Zeszyty Naukowe Zbliżenia Cywilizacyjne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Uwarunkowania skłonności do palenia papierosów. Wyniki modelowania równań strukturalnych
    Autorzy:
    Czaderny, Krzysztof
    Powiązania:
    https://bibliotekanauki.pl/articles/1827684.pdf
    Data publikacji:
    2017-06-02
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    lung cancer
    cancer prevention
    cancer control
    smoking
    masculinity
    childhood
    SEM
    structural equation modeling
    epidemiology
    health gap
    Opis:
    According to the age-period-cohort projection of lung cancer incidence (ICD-10 codes C33-C34), smoking prevention will be crucial for both men and women longevity. Lung cancer remains the main cancer cause of death among males in Poland. In 2014 the number of deaths in Poland caused by lung cancer among men was more than twice as high as for women. The study is focused on identification of attitudes influencing the propensity to smoke, which is performed by structural equation modelling (SEM) based on weighted least squares means and variance adjusted (WLSMV) estimation. Good fit of the presented models is demonstrated by RMSEA, NNFI and CFI values. Reliability of scales is assessed by ordinal alpha and ordinal theta coefficients. Commitment to learning in childhood exhibits the highest standardized effect on propensity to smoke, which is an argument for youth smoking prevention. Structural equation model was estimated for men and women separately because of gender differences in smoking determinants. A strong character, individualism and self-reliance are the factors, which increase smoking propensity among males. These can be treated as features of masculinity and are not statistically important determinants of being a smoker for females. Depressive disorders, being a victim of violence as adults are statistically significant determinants of smoking among women.
    Źródło:
    Studia Demograficzne; 2017, 171, 1; 49-69
    0039-3134
    Pojawia się w:
    Studia Demograficzne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-4 z 4

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