Skocz do pozycji: 1.

Tytuł:

Motives for the choice of not undergoing breast reconstruction

Autorzy:

Szadowska-Szlachetka, Zdzisława
Charzyńska-Gula, Marianna
Muzyczka, Katarzyna
Dobrowolska, Beata
Stanisławek, Andrzej

Powiązania:

https://bibliotekanauki.pl/articles/972568.pdf

Data publikacji:

2016

Wydawca:

Instytut Medycyny Wsi

Tematy:

breast cancer
breast reconstruction motives

Opis:

Introduction and objective. Currently, most women with less advanced breast cancer are offered operations with breast conserving treatment; however, if it is necessary to completely remove the breast, the patients may benefit from free breast reconstruction. The aim of the study was to determine the motives for breast reconstruction after mastectomy or decisive reasons for rejecting this treatment. Material and methods. The study included 241 women hospitalized in Polish oncological hospitals who were divided into two groups: 55.19% (n=133) were women after mastectomy; 44.81% (n=108) after breast reconstruction. Quantitative approach with the use of survey method was utilised. Results. Women who wished to undergo breast reconstruction were generallyy younger, better educated and more often professionally active. For women who wished to undergo breast reconstruction, the most important aspect was the willingness to improve their body image, their mental well-being, the inconvenience connected with wearing the prosthesis, better sexual relations with husband/partner, and the possibility of exposing the neckline without discomfort. The strongest correlation was found between women’s young age and their functioning in a relationship. Women after mastectomy, who decided not to undergo a breast reconstruction, were afraid of another operation, suffering, and they believed that there were more important issues. Conclusions. The study revealed a relationship between the lack of knowledge, in which hospital breast reconstruction procedure can be performed and the lack of motivation for undergoing the procedure. Women who have had knowledge of the possibility of a free breast reconstruction were younger, better educated and more often lived in the city.

Źródło:

Journal of Pre-Clinical and Clinical Research; 2016, 10, 1; 39-44
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 2.

Tytuł:

Neoadjuvant therapy in breast cancer – objectives and tasks

Autorzy:

Ostańska, Elżbieta
Bartusik-Aebisher, Dorota
Aebisher, David
Kaznowska, Ewa

Powiązania:

https://bibliotekanauki.pl/articles/454710.pdf

Data publikacji:

2019

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

neoadjuvant therapy (NCT)
breast cancer (BC)
triple negative breast cancer (TNBC)

Opis:

Introduction. Neoadiuvant therapy (NCT) in the treatment of breast cancer is employed for patients with early stage disease or with inoperable disease. NCT can decrease the tumor volume. It can facilitate breast conservation therapy. Response to NCT is a strong predictor of outcome breast cancer (BC). Direct target therapies has markedly improved the result of treatment BC. Aim. Therapy for breast cancer continues to improve. The importance of tumor burden on local control rates will be in the future. Material and methods. This analysis was performed using a systematic literature search. Results. The latest scientific reports give hope for greater safety and a better life for patients based on optimized and effective therapy. Conclusion. Currently, improving the effectiveness of breast cancer treatment is mainly related to the optimal use of classic therapeutic strategies. New classes of substances have been approved for treatment or are in advanced stages of clinical development.

Źródło:

European Journal of Clinical and Experimental Medicine; 2019, 2; 153-156
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 3.

Tytuł:

Impact of selected environmental factors on attendance in the Breast and Cervical Cancer Early Detection Programme in the Wielkopolska Province of Poland during 2007–2012

Autorzy:

Kycler, Witold
Kubiak, Anna
Rzymski, Paweł
Wilczak, Maciej
Trojanowski, Maciej
Roszak, Magdalena
Włoszczak-Szubzda, Anna
Rzymska, Izabela

Powiązania:

https://bibliotekanauki.pl/articles/989556.pdf

Data publikacji:

2017

Wydawca:

Instytut Medycyny Wsi

Tematy:

screening
breast cancer
cervical cancer

Opis:

Breast and cervical cancer represent a significant health and economic issue for Polish society, although if detected early, both can be cured successfully. For this reason, since 2006, according to the National Cancer Combat Programme, populationbased screening programmes have been implemented, aimed at reducing the mortality and morbidity for breast and cervical cancer. The aim of this study is to determine which of the selected four environmental factors affect attendance for screening mammography and cytology. Analysis included data from questionnaires filled in during mammography by 582,959 women aged 50–69 years, and 288,142 women during cytology, aged 25–59 years, in 2007–2012 in the Wielkopolska Province of Poland. It was found that the impact of medical staff on the attendance for cytological screening was the strongest statistically significant factor (p = 0,0001). Invitation by name (p=0,001) and other factors (p= 0,0001) also affected the attendance. In the cytological screening, medical staff was the factor that had the greatest impact on attendance. Other factors, such as self-reporting, increased participation in the next screening rounds, although the factors that affect attendance changed over time. Their constant analysis is essential for the efficient and effective evaluation of screening programsme.

Źródło:

Annals of Agricultural and Environmental Medicine; 2017, 24, 3
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 4.

Tytuł:

Nowotwór piersi – problemy i jakość życia kobiet po mastektomii
Breast cancer – problems and quality of women’s life after mastectomy

Autorzy:

Ciechanowska, Karolina
Krajewska, Karolina
Antczak-Komoterska, Anna

Powiązania:

https://bibliotekanauki.pl/articles/1029746.pdf

Data publikacji:

2018

Wydawca:

Państwowa Uczelnia Zawodowa we Włocławku

Tematy:

breast cancer
mastectomy
prevention

Opis:

Introduction. Breast cancer is one of the most frequently reported cases of cancer among women. Prevention and a healthy lifestyle offer a significant opportunity to avoid mastectomy which is the most radical form of treatment. The aim. The aim of the work is to present the review of literature on health promotion, prevention and the way women cope with everyday life after surgical removal of the breast. Overview. A number of factors contribute to the development of breast cancer. A crucial aspect of prevention is the enhancement of pro-health behaviors among women, which helps to reduce the risk of disease. Mastectomy is one of many methods of treatment for breast cancer. The quality of life of women after mastectomy is significantly affected. The most common problem is the lack of self-acceptance, a changed body image. Conclusions. Statistics show a substantial increase in the burden of cancer and the number of deaths from breast cancer. The results of the research among post-mastectomy women indicate huge changes in the mental and physical sphere of their functioning.
Wstęp. Rak piersi jest jednym z najczęściej odnotowywanych przypadków nowotworów wśród kobiet. Profilaktyka oraz zdrowy styl życia stwarzają szansę na unikanie radykalnej formy leczenia jaką jest mastektomia. Cel. Celem pracy jest przegląd piśmiennictwa obejmujący zakres promocji zdrowia, profilaktyki oraz sposobu radzenia sobie kobiet po chirurgicznym usunięciu piersi. Przegląd. Szereg czynników sprzyja rozwojowi raka piersi. Bardzo istotnym aspektem profilaktyki jest potęgowanie zachowań prozdrowotnych wśród kobiet, co sprzyja zmniejszeniu ryzyka wystąpienia choroby. Mastektomia jest jedną z wielu metod leczenia raka piersi. Jakość życia kobiet po mastektomii ulega znacznej zmianie. Najczęściej występującym problemem jest brak akceptacji własnej osoby, zmienionego obrazu ciała. Wnioski. Dane statystyczne wskazują na przyrost liczby zachorowań i zgonów z powodu raka piersi. Wyniki badań wśród kobiet po mastektomii wskazują na ogromne zmiany w sferze psychicznej oraz fizycznej ich funkcjonowania.

Źródło:

Innowacje w Pielęgniarstwie i Naukach o Zdrowiu; 2018, 3, 4; 91-99
2451-1846

Pojawia się w:

Innowacje w Pielęgniarstwie i Naukach o Zdrowiu

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 5.

Tytuł:

Results of a multi-centre survey concerning the treatment of hormone-dependent breast cancer in Poland in 2009–2013

Autorzy:

Jagiełło-Gruszfeld, Agnieszka

Powiązania:

https://bibliotekanauki.pl/articles/1065050.pdf

Data publikacji:

2015

Wydawca:

Medical Education

Tematy:

breast cancer
hormonal therapy

Opis:

In order to present a reliable picture of hormone-dependent breast cancer treatment in Poland, an on-line survey has been conducted in 19 oncology centres. As a result, data on the treatment of 486 patients have been obtained (405 of them initially presenting with stage I–III of disease advancement, and 81 representing stage IV). It has been concluded that in the majority of cases the treatment in question involves combined therapy, including chemotherapy, hormonal therapy, targeted molecular therapy, radiotherapy, and surgical methods with reference to the group of patients subjected to radical treatment.

Źródło:

OncoReview; 2015, 5, 1; A21-A26
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 6.

Tytuł:

Knowledge about prevention, risk factors and treatment in women with diagnosed breast cancer. Whether the disease affects their healthy behaviour?

Autorzy:

Nowicki, Andrzej
Rusak, Karolina
Rhone, Piotr

Powiązania:

https://bibliotekanauki.pl/articles/1065232.pdf

Data publikacji:

2015

Wydawca:

Medical Education

Tematy:

breast cancer
knowledge
prevention

Opis:

Objective. The assessment of knowledge about prevention and risk factors of women with diagnosed breast cancer. Material and methods. The study involved 100 women aged from 28 to 82 years (median 56.2 years) who were treated at the Oncology Center in Bydgoszcz in 2014 for breast cancer. Author’s original questionnaire containing questions on knowledge about breast cancer as well as environmental and demographic data was used in this research. Results. Self-examination of a breast was made by 83% of women, 85% of women benefited from invitations for mammography. 56% of women knew how often mammography should be repeated but only 28% knew at what age it should be started. Tumor in a breast (20.5%) and “pulling” nipples (14.4%) were the most frequently reported symptoms of a cancer. In terms of risk factors, genetics (32.2%) and unhealthy lifestyle (16.3%) were the factors pointed by women most often. Every third women indicated only one factor while every four indicated three factors. 69% of the respondents increased their knowledge after falling ill, from the Internet (20.5%) as well as from information leaflets and brochures (16.6%). Women’s knowledge about breast cancer was at the edge of low and average levels and the average value was 11.7 points. More knowledge had women with higher education 12.95 points, single 12.9 and young women 12.3. Conclusions. The knowledge about the disease among women with diagnosed breast cancer was unsatisfactory and did not depend on age, marital status, place of residence, type of work but on education level only. Older and uneducated women had less knowledge, particularly about factors increasing the risk of developing the disease. The Internet, information leaflets and brochures were the primary source of knowledge about the disease, not a doctor or a nurse. Women with breast cancer were aware of the importance of preventive tests. They declared that they can perform self-examination. The most frequently reported symptoms of cancer are tumor and “pulling” nipples.

Źródło:

OncoReview; 2015, 5, 2; A81-90
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 7.

Tytuł:

Stomach metastasis from breast cancer-mimicking linitis plastica

Autorzy:

Czerko, Katarzyna
Ostrowski, Michał
Bodnar, Lubomir

Powiązania:

https://bibliotekanauki.pl/articles/3200732.pdf

Data publikacji:

2022-09-30

Wydawca:

Medical Education

Tematy:

breast cancer
gastric metastases

Opis:

We report a rare case of metastatic gastric cancer from invasive carcinoma of the breast (BC) as the first symptom of disease-mimicking primary gastric linitis plastica.

Źródło:

OncoReview; 2022, 12, 3; 65-67
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 8.

Tytuł:

Cardiotoxicity in breast cancer patients after radiotherapy – modern methods of minimizing the dose to the heart and dilemmas of choosing critical cardiac structures for monitoring dose distribution

Autorzy:

Pudełek, Katarzyna
Pudełek, Jacek
Nawrocki, Sergiusz

Powiązania:

https://bibliotekanauki.pl/articles/1064839.pdf

Data publikacji:

2016

Wydawca:

Medical Education

Tematy:

breast cancer
cardiotoxicity
radiotherapy

Opis:

Radiotherapy in breast cancer patients is an important component of multidisciplinary treatment. It reduces the risk of local recurrence and mortality from breast cancer. However, it can lead to secondary effects due to the presence of the heart within the irradiation field. Adjuvant radiation therapy for breast cancer increases the risk of coronary artery disease, myocardial infarction and cardiovascular death. It is important to determine the optimal treatment to minimize cardiotoxicity. Modern radiotherapy techniques may reduce radiation-induced cardiac toxicity, but it is necessary to determine the most sensitive structures within the heart, tolerance doses, and methods for early detection and monitoring of adverse effects.

Źródło:

OncoReview; 2016, 6, 3; A113-117
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

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Skocz do pozycji: 9.

Tytuł:

Retrospective analysis of local recurrence rate in breast cancer patients treated at the department of surgical oncology in Łódź between 2009 and 2013

Autorzy:

Morawiec, Jan
Dziki, Adam
Morawiec, Zbigniew
Kołacińska, Agnieszka

Powiązania:

https://bibliotekanauki.pl/articles/1395718.pdf

Data publikacji:

2014-02-01

Wydawca:

Index Copernicus International

Tematy:

breast cancer
local recurrence

Opis:

The aim of the study was to analyze clinicopathological features in breast cancer patients with local recurrence (LR). Material and methods. A retrospective analysis of database of breast cancer patients operated on in the Department of Surgical Oncology in Łódź from 2 January 2009 to 30 June 2013, identified 1080 women with primary breast cancer and 11 patients with LR. Results. LR rate was 0.23% per year. True recurrence (TR) occurred more frequently in patients with luminal B molecular subtype, in HER-2 positive and in triple-negative subgroups. In one patient with luminal -A subtype new primary (triple negative) occurred. TR were noted predominantly in patients with axillary lymph nodes metastases and with luminal B subtype who did not receive adjuvant chemotherapy but were given only endocrine therapy. LR were observed more frequently in patients who did not receive adjuvant radiotherapy or this treatment was delayed. Minimal surgical margins in postoperative specimens measured by pathologist were 4-25 mm, mean 9.5 mm. Conclusions. The LR rate in patients operated on breast cancer in the Department of Surgical Oncology between 2009 and 2013 was low. TR was diagnosed in patients with non- luminal A breast cancer despite wide surgical margins, especially if the patients did not receive optimal adjuvant systemic treatment or radiotherapy was delayed or omitted. Complete cancer excision followed by an immediate implementation of optimal adjuvant treatment seems to be crucial especially in patients with poor tumor biology.

Źródło:

Polish Journal of Surgery; 2014, 86, 2; 77-81
0032-373X
2299-2847

Pojawia się w:

Polish Journal of Surgery

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 10.

Tytuł:

Fertility and breast cancer

Autorzy:

Kufel-Grabowska, Joanna

Powiązania:

https://bibliotekanauki.pl/articles/1064776.pdf

Data publikacji:

2016

Wydawca:

Medical Education

Tematy:

breast cancer during pregnancy
breast cancer in young women
fertility
fertility preservation strategies

Opis:

Breast cancer is the most common cancer among females worldwide. The mean age of breast cancer patients is > 60 yrs old, and it is seldom found in women < 40 yrs old (6.5%) and in very young women < 35 yrs old (0.6%). In young females, fertility and all its aspects are an additional therapeutic challenge. Before initiating treatment, the oncologist should offer effective contraception to be applied throughout the therapy, bearing in mind that fertility preservation is of utmost importance. When it comes to breast cancer in pregnancy, the attending physician should use a therapy which is safe for both the mother and the foetus. Chemotherapy, radiotherapy, hormonal therapy and immunotherapy can, to a lesser or greater degree, damage the ovarian function resulting in amenorrhea in women < 50 yrs (33–76%). However, owing to fertility preservation strategies, more and more pregnancies are successful, even in breast cancer survivors.

Źródło:

OncoReview; 2016, 6, 4; A157-161
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

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Skocz do pozycji: 11.

Tytuł:

Determinants of women’s behavior in breast cancer prevention

Autorzy:

Nagórska, Małgorzata
Aksamit, Magdalena
Krygowska, Krystyna
Bassara-Nowak, Dorota

Powiązania:

https://bibliotekanauki.pl/articles/454727.pdf

Data publikacji:

2019

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

attitudes
breast cancer
knowledge
prophylaxis

Opis:

Introduction. According to statistics, breast cancer is the second leading cause of death in Poland. Progress in treatment and diagnosis gives an opportunity of a quick diagnosis, but women are reluctant to undergo prophylaxis screening. Aim. To identify women’s attitudes about breast cancer prophylaxis. Material and methods. The diagnostic survey was conducted in a group of 200 women. The research tool was the questionnaire developed by the authors. Results. Knowledge about breast cancer and prophylaxis was on an average level. Nearly half of the women surveyed (45.5%) declared that they do not ask for a breast examination while visiting a gynecologist. Only 26.8% of the surveyed women were systematically subjected to preventive examinations for breast cancer, while 18.7% of them performed breast self-examination. Every fifth respondent used invitation for a free mammogram. Conclusion. The women’s knowledge about breast cancer is average, but it does not translate into their attitudes towards the prevention of this cancer. Most women niether perform breast self-examination nor benefit from free prophylaxis programs. Younger respondents most often use the Internet. Education and place of residence do not affect the participation of women in preventive examinations for breast cancer.

Źródło:

European Journal of Clinical and Experimental Medicine; 2019, 2; 123-130
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 12.

Tytuł:

The use of fulvestrant in patients with advanced breast cancer

Autorzy:

Kufel-Grabowska, Joanna

Powiązania:

https://bibliotekanauki.pl/articles/1035843.pdf

Data publikacji:

2018

Wydawca:

Medical Education

Tematy:

breast cancer
fulvestrant
hormone therapy

Opis:

Breast cancer is the most common malignancy in women in Poland and the entire world, but thanks to early diagnostics and efficacious therapeutic methods, its prognosis is good. In some patients with advanced breast cancer, long-term survival is observed, which is why it is essential to select the most appropriate therapy, and to follow up on the course of disease and possible adverse events related to the treatment applied. The slow development of hormone-receptor-positive cancer, and a multitude of therapeutic options constitute a real challenge in palliative treatment. The use of fulvestrant resulted in a good response in both of the presented cases, and did not in any way comprise the daily lives of the patients over a long period of time.

Źródło:

OncoReview; 2018, 8, 1; 15-18
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

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Skocz do pozycji: 13.

Tytuł:

Efficacy and safety of liposomal doxorubicin in a patient treated for metastatic breast cancer

Autorzy:

Streb, Joanna
Słowik, Agnieszka

Powiązania:

https://bibliotekanauki.pl/articles/1065206.pdf

Data publikacji:

2015

Wydawca:

Medical Education

Tematy:

breast cancer
cardiotoxicity
liposomal doxorubicin

Opis:

Liposomal doxorubicin is a newer form of chemotherapeutic agents that, due to its own special properties, preferably accumulates in cancer tissue. On the other hand, it shows lower affinity to cardiomyocytes and in this way is less cardiotoxic. As a result of that, there is the possibility to use liposomal form of doxorubicin until disease progression or chemotherapy intolerance in palliative setting, without treatment cessation after reaching the maximum cumulative dose of conventional doxorubicin. In this article we describe the case of a female patient diagnosed with breast cancer who was primary treated with adjuvant treatment, including chemotherapy and in whom a disease recurrence occurred after seven years of observation. As a primary palliative treatment the patient received chemotherapy based on liposomal doxorubicin and cyclofosphamide with a very good tolerance. The initial response was partial remission in lungs and in mediastinal lymph nodes. During the whole course of therapy there were no pathological changes in electrocardiogram, no signs and no symptoms of congestive heart failure, and the left ventricular ejection fraction was within normal limits.

Źródło:

OncoReview; 2015, 5, 2; A67-70
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

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Skocz do pozycji: 14.

Tytuł:

Everolimus – effectively reverses acquired resistance on endocrine therapy of patients with advanced breast cancer. A case report

Autorzy:

Grela-Wojewoda, Aleksandra
Kruczała, Maksymilian
Cedrych, Ida

Powiązania:

https://bibliotekanauki.pl/articles/1065382.pdf

Data publikacji:

2014

Wydawca:

Medical Education

Tematy:

breast cancer
endocrine therapy
everolimus

Opis:

Breast cancer is the most common malignancy among women in Poland. Endocrine therapy is the first line of treatment in hormone-receptor-positive advanced breast cancer. Progression during endocrine therapy is unavoidable. Administration of mTOR inhibitor gives a chance of reversing the acquired resistance. This paper presents a case report of a patient with metastatic breast cancer successfully treated with everolimus added to endocrine therapy.

Źródło:

OncoReview; 2014, 4, 3; A117-120
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

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Skocz do pozycji: 15.

Tytuł:

The Influence Of Obesity On Results Of AT (Doxorubicin Plus Docetaxel) Neoadjuvant Chemotherapy In Locally Advanced Breast Cancer Patients

Autorzy:

Karpińska, Agnieszka
Safranow, Krzysztof
Kładny, Józef
Sulżyc-Bielicka, Violetta

Powiązania:

https://bibliotekanauki.pl/articles/1395628.pdf

Data publikacji:

2015-05-01

Wydawca:

Index Copernicus International

Tematy:

obesity
neoadjuvant chemotherapy
breast cancer

Opis:

The achieve pathologic complete response is proven to be the most important parameter of prognosis. Thereports evaluating the impact of obesity on the obtained pathologic response to chemotherapy are unequal. The aim of the study was to evaluate in locally advanced breast cancer patients, treated with AT(doxorubicin plus docetaxel) neoadjuvant chemotherapy: 1. The relationship of obesity with obtaining pathological response. 2. The relationship of obesity and free of disease recurrence survival (DFS) and overall survival (OS) associated with the tumour. Material and methods. A retrospective study was carried out in a group of 105 patients with locally advanced breast cancer, treated with AT neoadjuvant chemotherapy and then treated with radical surgery. Two variants of pathological response have been adopted: a pCR (T0N0) and pCR1 (TisN0, TxN1, T1N0, T1N1, T0N1). The relationship of obesity with pathological response and survival was investigated. Results. In univariate analysis the pCR1 was obtained with its arising from the borderline of statistical significance with lower incidence of obesity. In pCR1 multivariate analysis, negative pCR1 relationship with obesity was on the borderline of the statistical significance. The multivariate analysis showed a significant negative association OS with obesity (p=0.047) and positive with the occurrence of menopause (p = 0.029). Conclusions. In patients with locally advanced breast cancer treated with AT neoadjuvant chemotherapy. 1. Obesity seems to be an independent and unfavourable predictor of the lack of obtaining pCR1 pathological response 2. In the multivariate analysis, the obesity was a significant independent factor related to shorter OS.

Źródło:

Polish Journal of Surgery; 2015, 87, 5; 231-237
0032-373X
2299-2847

Pojawia się w:

Polish Journal of Surgery

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 16.

Tytuł:

Role of nurse in the breast cancer education

Autorzy:

Cetlova, Lada
Dvorakova, Vlasta

Powiązania:

https://bibliotekanauki.pl/articles/2141042.pdf

Data publikacji:

2011

Wydawca:

Instytut Studiów Międzynarodowych i Edukacji Humanum

Tematy:

education
breast cancer
patient
nurse

Opis:

Incidence of female breast cancer in our population remains very high and the incidence increase every year. Breast cancer and following demanding oncological treatment extensively influence life of female patients. It intervene biological, psychical and social life of patient. Objective of our research was to check how women are informed about preventive precautions and how they are following them. Our research sample were randomly selected women of all age groups. Our results showed that it is necessary to increase activity in the area of education, increase personal responsibility in area of breasts self-examination and better inform about the influence of obesity to breast cancer incidence. Considering our previous experience in health care we were surprised that the role of nurse in education process is very low. We think that general nurses have enough opportunities to use daily contacts with patients to inform and lecture them.

Źródło:

Humanum. Międzynarodowe Studia Społeczno-Humanistyczne; 2011, 2(7); 315-320
1898-8431

Pojawia się w:

Humanum. Międzynarodowe Studia Społeczno-Humanistyczne

Dostawca treści:

Biblioteka Nauki

/5

Artykuł

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Skocz do pozycji: 17.

Tytuł:

Active dynamic thermography in mammography

Autorzy:

Kaczmarek, M.
Nowakowski, A.

Powiązania:

https://bibliotekanauki.pl/articles/1965793.pdf

Data publikacji:

2004

Wydawca:

Politechnika Gdańska

Tematy:

thermography
breast cancer
mathematical modelling

Opis:

We discuss limitations of the known methods of IR imaging in diagnostics of breast cancer. In conclusion we show that the known methods, based on simple observation of external temperature distribution, are not fully effective. Even advanced pattern recognition could not help in analysis of static images. May active dynamic thermography, known in non-destructive testing of materials, be of any help in breast cancer diagnostics? Analysis of thermal transients forced by external thermal excitation shows, even on simple models, that one may expect a visible improvement in resolution after such excitation. Applied models allow analysis of both static and active thermograms. Basing on the models one may recognise elements of the internal structure of a breast not visible in static pictures. This method, new in clinical practice, seems to be promising, but requires further studies.

Źródło:

TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk; 2004, 8, 2; 259-267
1428-6394

Pojawia się w:

TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 18.

Tytuł:

Physiotherapy in women after breast cancer treatment – review

Autorzy:

Skutnik, K.
Ustymowicz, W.
Zubrewicz, K.
Zińczuk, J.
Kamińska, D.
Pryczynicz, A.

Powiązania:

https://bibliotekanauki.pl/articles/1918836.pdf

Data publikacji:

2019

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

breast cancer
rehabilitation
mastectomy
physiotherapy

Opis:

Introduction: Breast cancer is the most common malignant tumor in women in the Polish region. Surgery is a basic method of breast cancer treatment. Surgery often carries a lot of unwanted changes as follows: limitation of mobility in the shoulder joint on the operated side, secondary lymphoedema, post mastectomy pain syndrome (PMPS), reduction of muscle strength or disorders in body posture. Therefore, the implementation of physiotherapeutic activities that are designed to prevent and eliminate postoperative complications seems very important. The main aim of this work was to present physiotherapeutic management in women after mastectomy based on the analysis of available literature. The physiotherapeutic process can be divided into three periods: early hospital, early ambulatory and the late ambulatory period. In the first period, active slow exercises, self-support of the upper limb on the operated side and breathing exercises on the thoracic track are used to prevent circulatory disorders, pulmonary complications, and edema. The early ambulatory period includes corrective exercises, general improvement exercises, stretching and learning of automatic massage of the upper limb of the operated side. The last period should be enriched by recreational methods of physical activity such as swimming, cycling or Nordic walking to maintain physical fitness, proper mobility of the shoulder girdle and improve the patient's psychophysical state. It is very important the patient regular continues the rehabilitation program after curing of breast cancer as well. In the case of secondary lymphoedema of the upper limb, comprehensive rehabilitation physiotherapy is used, consisting of manual lymphatic drainage, healing exercises, compression therapy, and skin care. Conclusions: Physiotherapy in women after breast cancer surgery is a complex and long-term process. Physiotherapeutic methods are effective in treating complications after surgery of breast cancer surgery. It is necessary to constantly update the physio-therapy knowledge in women after breast cancer surgery.

Źródło:

Progress in Health Sciences; 2019, 1; 162-168
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 19.

Tytuł:

Everolimus with exemestane in elderly breast cancer patients – case report

Autorzy:

Jagiełło-Gruszfeld, Agnieszka

Powiązania:

https://bibliotekanauki.pl/articles/1065836.pdf

Data publikacji:

2014

Wydawca:

Medical Education

Tematy:

breast cancer
elderly
everolimus
exemestan

Opis:

Treating elderly patients suffering from metastatic breast cancer still constitutes a significant therapeutic problem. The possibility of administering everolimus in combination with exemestane appears to be a promising therapeutic option in the case of hormone-dependent cancers, without HER2 receptor overexpression.

Źródło:

OncoReview; 2014, 4, 1; A33-36
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 20.

Tytuł:

Imaging methods of early detection and screening for breast cancer. A review

Autorzy:

Gustalik, Joanna
Bartusik-Aebisher, Dorota
Aebisher, David
Kaznowska, Ewa

Powiązania:

https://bibliotekanauki.pl/articles/454888.pdf

Data publikacji:

2019

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

breast cancer
breast MRI
early detection
screening

Opis:

Introduction. Breast cancer is the most frequent neoplasm among women. That is the reason why scientists all over the world are attempting to improve early detection methods of this particular malignancy. Aim. The most common and most widely used examination methods for screening for and detecting breast cancer is presented herein. Material and methods. This review was performed according to systematic literature search of three major bibliographic databases. Results. Available data suggest that incidence and mortality in high-resource countries has been declining whereas incidence and mortality in low-resource countries has been increasing. Conclusion. The role of a physician is to select the most suitable one for each patient in order to obtain the best result. No matter the method however, between 2005 and 2011, the 5-year relative survival was found to be 89%. This is thought to be due to both the increase in utilization of population-wide screening, as well as advances in treatment.

Źródło:

European Journal of Clinical and Experimental Medicine; 2019, 2; 142-145
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 21.

Tytuł:

Same quality of life for polish breast cancer patients treated with mastectomy and breast reconstruction or breast-conserving therapy

Autorzy:

Szutowicz-Wydra, Beata
Wydra, Jacek
Ciesielski, Maciej
Kruszewski, Wiesław J
Szajewski, Mariusz
Walczak, Jakub
Hansdorfer-Korzon, Rita

Powiązania:

https://bibliotekanauki.pl/articles/1393915.pdf

Data publikacji:

2016

Wydawca:

Index Copernicus International

Tematy:

breast cancer
breast surgery
quality of life

Opis:

Breast cancer often requires combined oncologic treatments, the base of which is surgery. Quality of life (QoL) after each surgical procedure may influence the process of decision making among women, who qualify for multiple oncological strategies. Our knowledge about QoL in breast cancer patients is derived from comparative studies. Results may differ, depending on country, culture, and societal relations. The aim of the study was to investigate the quality of life of Polish patients treated with breastconserving therapy (BCT) or mastectomy with breast reconstruction. Material and methods. The study involved women who underwent surgery for breast cancer in the Department of Surgical Oncology of the Gdynia Oncology Center from September 2010 to November 2013. Eighty-two breast reconstructions (in 79 patients) and 226 BCT procedures were performed. QoL was measured with the use of EORTC QLQ-C30 and QLQ-BR23 questionnaires. Results. Global QoL was high in both groups and did not differ significantly. Body image was slightly better after BCT than after mastectomy with breast reconstruction, but sexual QoL was lower. Future perspective was quite low in both groups. Disease symptoms were not bothering. Conclusions. The global QoL among Polish breast cancer patients treated with BCT or mastectomy with breast reconstruction is high and does not differ between groups. There is a need for anxiety and disease-related fear prophylaxis and for the improvement of sex life of breast cancer survivors.

Źródło:

Polish Journal of Surgery; 2016, 88, 5; 464-474
0032-373X
2299-2847

Pojawia się w:

Polish Journal of Surgery

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 22.

Tytuł:

Coffee and its Biologically Active Components: Is There a Connection to Breast, Endometrial, and Ovarian Cancer? - a Review

Autorzy:

Witkowska, Anna M.
Mirończuk-Chodakowska, Iwona
Terlikowska, Katarzyna M.
Kulesza, Kamila
Zujko, Małgorzata E.

Powiązania:

https://bibliotekanauki.pl/articles/1447277.pdf

Data publikacji:

2020-05-25

Wydawca:

Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie

Tematy:

coffee
caffeine
breast cancer
ovarian cancer
Endometrial Cancer

Opis:

Coffee is an important dietary source of biologically active components, not to mention caffeine, phenolic acids, and diterpenes. It has been suggested that selected coffee secondary metabolites may beneficially modulate several mechanisms of anti-cancer protection. This literature review was intended to present current knowledge related to coffee and its components and hormone-dependent female cancers, such as breast, endometrial and ovarian cancer, and to identify gaps in research that may be exploited in the future. The search for studies was conducted through electronic databases. Publications on coffee composition, coffee preparation and brewing methods, in vitro and in vivo experiments with the use of substances naturally present in coffee, observational studies, and meta-analyses were collected. In population studies, the greatest attention has been paid to the anticancer effect of caffeinated coffee and/or caffeine. In general, most studies and meta-analyses indicated that there was no clear correlation between coffee and breast cancer or ovarian cancer. Some subgroups of women may benefit from coffee consumption. This is the case for post-menopausal women with regard to the risk of breast cancer and obese women with regard to the risk of endometrial cancer. This paper identifies a number of issues for future research, related to a better understanding of the anti-cancer mechanisms of coffee compounds and further research that would focus on specific target groups, taking into account both the different methods of coffee preparation and lifestyle factors that may influence the results.

Źródło:

Polish Journal of Food and Nutrition Sciences; 2020, 70, 3; 207-222
1230-0322
2083-6007

Pojawia się w:

Polish Journal of Food and Nutrition Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 23.

Tytuł:

Epidemiology of breast cancer in Podkapackie voivodship

Autorzy:

Gustalik, Joanna
Bartusik-Aebisher, Dorota
Ostańska, Elżbieta
Przyczyna, Piotr
Osuchowski, Michał
Aebisher, David
Galiniak, Sabina
Kaznowska, Ewa

Powiązania:

https://bibliotekanauki.pl/articles/454657.pdf

Data publikacji:

2019

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

breast cancer
statistics
epidemiology
podkarpackie voivodship

Opis:

Introduction. Breast cancer is the second most prevalent reason for cancer deaths after lung cancer. Incidence rates have increased worldwide. Aim. To present epidemiology of breast cancer in Podkapackie voivodship. Material and methods. This analysis was performed using a systematic literature search. Results. In the Podkarpackie voivodship up until 2014, the incidence rate of female breast cancer was rising and in 2015 it dropped by 68 cases. Even though the survival rate is increasing, it is still one of the leading causes of cancer deaths placing second after lung cancer. Conclusion. Mortality rate, unfortunately, rose gradually. This shows that even though there is a National Health Program aiming at breast cancer awareness and prevention, it is still not enough to reduce the number of breast cancer deaths.

Źródło:

European Journal of Clinical and Experimental Medicine; 2019, 3; 242-245
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 24.

Tytuł:

Intermittent pneumatic compression in patients with postmastectomy lymphedema

Autorzy:

Chmielewska, Daria
Stania, Magdalena
Błaszczak, Edward

Powiązania:

https://bibliotekanauki.pl/articles/551707.pdf

Data publikacji:

2016

Wydawca:

Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych

Tematy:

breast cancer
intermittent pneumatic compression
lymphedema.

Źródło:

Family Medicine & Primary Care Review; 2016, 4; 419-424
1734-3402

Pojawia się w:

Family Medicine & Primary Care Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 25.

Tytuł:

Breast Cancer in Art Painting

Autorzy:

Forma, Ewa
Bernaciak, Magdalena
Bryś, Magdalena

Powiązania:

https://bibliotekanauki.pl/articles/764935.pdf

Data publikacji:

2010

Wydawca:

Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego

Tematy:

breast cancer
art paintings
famous painters

Opis:

Breast cancer is an emotive cancer. It is a disease that affects a visible sexual organ and it is the commonest single cause of death of women between 40 and 60 years of age. Nevertheless, this type of cancer was infrequently depicted in art paintings. In this article the themes from the breast cancer in famous art paintings are discussed.

Źródło:

Acta Universitatis Lodziensis. Folia Biologica et Oecologica; 2010, 6; 61-68
1730-2366
2083-8484

Pojawia się w:

Acta Universitatis Lodziensis. Folia Biologica et Oecologica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 26.

Tytuł:

Multimodal Ultrasonic Imaging for Breast Cancer Detection

Autorzy:

Camacho, J.
Medina, L.
Cruza, J. F.
Moreno, J. M.
Fritsch, C.

Powiązania:

https://bibliotekanauki.pl/articles/176695.pdf

Data publikacji:

2012

Wydawca:

Polska Akademia Nauk. Czytelnia Czasopism PAN

Tematy:

ultrasound imaging
ultrasound tomography
breast cancer

Opis:

Ultrasound is used for breast cancer detection as a technique complementary to mammography, the standard screening method. Current practice is based on reflectivity images obtained with conventional instruments by an operator who positions the ultrasonic transducer by hand over the patient’s body. It is a non-ionizing radiation, pain-free and not expensive technique that provides a higher contrast than mammography to discriminate among fluid-filled cysts and solid masses, especially for dense breast tissue. However, results are quite dependent on the operator’s skills, images are difficult to reproduce, and state-of-the-art instruments have a limited resolution and contrast to show micro-calcifications and to discriminate between lesions and the surrounding tissue. In spite of their advantages, these factors have precluded the use of ultrasound for screening. This work approaches the ultrasound-based early detection of breast cancer with a different concept. A ring array with many elements to cover 360. around a hanging breast allows obtaining repeatable and operator-independent coronal slice images. Such an arrangement is well suited for multi-modal imaging that includes reflectivity, compounded, tomography, and phase coherence images for increased specificity in breast cancer detection. Preliminary work carried out with a mechanical emulation of the ring array and a standard breast phantom shows a high resolution and contrast, with an artifact-free capability provided by phase coherence processing.

Źródło:

Archives of Acoustics; 2012, 37, 3; 253-260
0137-5075

Pojawia się w:

Archives of Acoustics

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 27.

Tytuł:

Detection of circulating breast cancer cells in peripheral blood by a two-marker reverse transcriptase-polymerase chain reaction assay.

Autorzy:

Fabisiewicz, Anna
Kulik, Jadwiga
Kober, Paulina
Brewczyńska, Elżbieta
Pieńkowski, Tadeusz
Siedlecki, Janusz

Powiązania:

https://bibliotekanauki.pl/articles/1041553.pdf

Data publikacji:

2004

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

RT-PCR
breast cancer
molecular markers

Opis:

The aim of this study was to use a two-marker assay for the detection of breast cancer cells circulating in patients' blood. We have applied a PCR-based methodology to follow up the possibility of the development of metastatic disease in stage I and II patients who had undergone curative surgery. Since the number of circulating cancer cells in peripheral blood is very low, the technique for their detection needs to be not only highly sensitive, but also very specific. The reverse transcriptase-polymerase chain reaction (RT-PCR) technique may improve the sensitivity of breast cancer cell detection up to only a few cells per one million. The principle of the RT-PCR assay is to amplify a messenger RNA characteristic for breast epithelial cells in a blood sample. Since we do not expect such cells to be circulating in peripheral blood of healthy subjects, detection of the characteristic mRNA should indicate the presence of circulating breast cancer cells. We analyzed the usefulness of three mRNA markers: cytokeratin 19 (CK19), mammaglobin (hMAM) and β subunit of human chorionic gonadotropin (β-hCG) for this test. Blood samples (112) were obtained from 55 patients, in stages I and II, with or without metastasis to regional lymph nodes (N0 or N1). We found that a two-marker assay increases the sensitivity of detection of breast cancer cells in comparison with a single-marker one. Combination of two tumor-specific mRNA markers, hMAM/CK19 or β-hCG/CK19, allowed the detection of circulating breast cancer cells in 65% of N1 patients and 38% of N0 patients. By comparison, the combination hMAM/β-hCG allowed the detection of circulating breast cancer cells in the blood of 68% of N1 patients and 46% of N0 patients. Addition of the third marker did not significantly increase the detection sensitivity.

Źródło:

Acta Biochimica Polonica; 2004, 51, 3; 747-755
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 28.

Tytuł:

Connecting the dots: understanding the relationship between religiosity, psychological resilience and depression in breast cancer patients

Autorzy:

Fradelos, E.C.

Powiązania:

https://bibliotekanauki.pl/articles/1918864.pdf

Data publikacji:

2019-08-26

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

Religiosity
breast cancer
depression
psychological resilience

Opis:

Introduction: Death anxiety, fear of abundance, isolation, stigma of the disease and medication side effects are among the most common sources of anxiety and depression in patients with breast cancer. Purpose: To examine the possible relationship between religiosity, psychological resilience and depression on breast cancer patients. Materials and methods: A cross-sectional design was employed in this study which 152 breast cancer patients participated. Data were collected with the following instruments: Patient Health Questionnaire-2-item scale, Connor-Davidson Resilience Scale 25 and Centrality of Religiosity Scale and a special designed sheet reporting social, demographic and clinical characteristics. Statistical analyses were conducted with the Statistical Package for the Social Science V25. Descriptive statistics such means, and frequencies were calculated and inferential statistics such correlation test, simple and multiple regression analysis were applied. Results: Approximately 1 in 3 patients suffered symptoms of depression while they were reporting moderate religiosity and resilience values. Based on the four-step mediation analysis religiosity was strongly associated with psychological resilience but it was not found to affect directly either depression, but psychological resilience can be a mediator between religiosity and depression. Conclusion: This study supports the notion thatreligiosity and spirituality can have a beneficial influence on health outcomes.

Źródło:

Progress in Health Sciences; 2019, 1; 98-104
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 29.

Tytuł:

Za gruba, za chuda, nieładna – problem społecznej stygmatyzacji osób o ciele nieidealnym

Autorzy:

Brandt, Anna
Buszman, Krystyna

Powiązania:

https://bibliotekanauki.pl/articles/2157775.pdf

Data publikacji:

2016

Wydawca:

Instytut Studiów Międzynarodowych i Edukacji Humanum

Tematy:

stigmatization
somatocentric attitudes
breast cancer
anorexia

Opis:

The aim of this paper is to present the phenomenon of social exclusion of persons whose body has been deformed due to disease process. Modern concepts of stigmatization and sociocultural aspects, which can be the background of social exclusion process, are going to be shown. Authors’ own research fo- cused on how the bodies of women after mastectomy and those suffering from anorexia are perceived in the society. In the lights of obtained results, stigmatization process is in the more advanced stage in women with anorexia than in those after mastectomy. In women after mastectomy it stops on social labeling, but in the context of anorexia it reaches the stage of social rejection according to Link and Phelan’s (2001) theory, which can be connected with social attribution of responsibility for having a stigma (somatic vs mental illness).

Źródło:

Społeczeństwo i Edukacja. Międzynarodowe Studia Humanistyczne; 2016, 1(20); 103-115
1898-0171

Pojawia się w:

Społeczeństwo i Edukacja. Międzynarodowe Studia Humanistyczne

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 30.

Tytuł:

Epidemiological profile and distribution of prognostic factors in invasive breast cancer among Algerian women

Autorzy:

Elbasyouni, Amel
Saadi, Leila
Baha, AbdelKarim

Powiązania:

https://bibliotekanauki.pl/articles/2047226.pdf

Data publikacji:

2021-09-22

Wydawca:

Medical Education

Tematy:

breast cancer
epidemiology
biomarkers
immunohistochemistry
prognostic

Opis:

Although the widespread of early screening and advanced medical therapies, the breast cancer incidence rate continues to rise among Algerian women. This retrospective study investigated mammary lesions’ epidemiological profile and histopathological characteristics and evaluated primary invasive breast cancer prognostic factors. We found that the incidence of breast cancer increases in middle- aged women between 40 and 60 years. Scarff Bloom Richardson grade II predominates in invasive breast cancer samples. In this study, molecular profiling shows that 82.1% of invasive tumours are hormone receptor-positive. A significant correlation is observed between the age of the patient and the SBR grade (p = 0.001) and with the hormone receptor expression (p = 0.001). In addition, the tumour grade is significantly correlated to oestrogen and progesterone receptor expression (p = 0.000; p = 0.000, respectively). Twenty-two per cent of cases were human epidermal growth factor receptor 2-positive. The Ki-67 proliferation index is expressed in 91% of breast cancer patients and was significantly associated with Scarff Bloom Richardson grade (p = 0.030), the progesterone receptor expression (p = 0.029) and with human epidermal growth factor receptor 2-positivity (p = 0.023). Primary breast cancer with a high grade is more frequent (31%) in young women under 40 years old, presenting 17% of our population. In summary, breast cancer patients in Algeria develop an unfavourable profile. Immunohistochemistry assay has played a pivotal role in assessing breast cancer predictive biomarkers improving the tumour behaviour and response to treatment.

Źródło:

OncoReview; 2021, 11, 4; 95-101
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 31.

Tytuł:

Satisfaction with life and health-promoting behaviours in the context of prevention and early detection of breast cancer in physically active women

Autorzy:

Nowicki, Andrzej
Kosicka, Beata
Lemanowicz, Marzena

Powiązania:

https://bibliotekanauki.pl/articles/1061804.pdf

Data publikacji:

2017

Wydawca:

Medical Education

Tematy:

breast cancer
life satisfaction
physical activity

Opis:

Objective: Assessment of the impact of life satisfaction in physically active women on their health promoting behaviours in terms of prevention and early detection of breast cancer. Materials and methods: The study, involving 100 women, was carried out in a fitness centre in Bydgoszcz in 2015. The research instruments used included the authors’ self-designed questionnaire and the SWLS life satisfaction score. Results: Women aged 25–34 constituted 57% of the study participants, with 82% of them domiciled in the city, and 74% of them holding secondary or higher education qualifications. 67% of them assessed their knowledge about breast cancer and breast cancer prevention programme as good, 65% of them believed it was impossible to protect oneself from cancer, 68% of them occasionally consumed alcohol. 89% of the respondents engaged in breast self-examination, and 68.4% of the subjects aged 25–34 considered excessive weight/obesity as a risk factor. 61.5% of women aged 45–60 were smokers. Respondents living in the city would dedicate one hour more for physical activity than those from the countryside. 93.2% of women with secondary/tertiary education carried out breast self-examination. Surveyed women received high scores on the scale of life satisfaction, averaging 25.69 points, they were less likely to smoke cigarettes, and more likely to engage in breast self examination (95.5%). Conclusions: Physically active women assess their knowledge on health-promoting behaviours well, lead a healthy lifestyle, and avoid breast cancer risk factors. Physically active women accomplish a high level of life satisfaction, which is especially true for married women with a higher education degree. On the other hand, life satisfaction does not correlate with age, place of residence or marital status. Women presenting a high level of life satisfaction are more involved in health-promoting behaviours, carry out regular breast self-examination, and undergo preventative medical check-ups.

Źródło:

OncoReview; 2017, 7, 1; 5-14
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 32.

Tytuł:

The influence of socio-demographic factors on making a decision related to the disease and treatment in women with breast cancer

Autorzy:

Nowicki, Andrzej
Wiśniewska, Kamila
Rhone, Piotr

Powiązania:

https://bibliotekanauki.pl/articles/1065312.pdf

Data publikacji:

2015

Wydawca:

Medical Education

Tematy:

breast cancer
prevention
socio-demographic factors

Opis:

Introduction. Socio-demographic factors may affect the decision making associated with the disease and the long-term results of treatment. Objective. Exploring the relationship between socio-demographic factors of women treated for breast cancer and decision- making associated with the disease and treatment. Material and methods. The study involved 100 women aged 30 to 72 (mean: 57 years) who were treated at the Oncology Center in Bydgoszcz in 2013–2014 due to breast cancer. A survey questionnaire on socio-demographic factors and data on knowledge about prevention and disease was used in the study. Results. The number of women performing breast self-examination decreased with age; 83% of patients over 50 years old and 76% (p = 0.0001) over 69 years old underwent mainly mammography (p = 0.03). Self-detection of breast tumor also decreased with age and was detected more frequently by the medical personnel (p = 0.0001). More educated women (85%) examined themselves more often than those with primary and vocational education (p = 0.001). According to our assessment, the number of women with knowledge about cancer decreased with age (p = 0.004). The same was true for women in a very good and good financial situation, with 94% of them declaring a higher knowledge level (p = 0.001). Conclusions. Women’s knowledge about breast cancer is not satisfactory, especially in older and less educated women. They obtain knowledge from the Internet mainly and from the medical staff in the smallest degree. Young women up to 49 years of age perform self-examination to detect breast cancer most often, while older women use mammography. Almost all women immediately report to the doctor and are admitted to clinics after detecting lesions with mammography or self-examination.

Źródło:

OncoReview; 2015, 5, 3; A125-132
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 33.

Tytuł:

Myocardial dysfunction related to trastuzumab therapy – is effective treatment always possible?

Autorzy:

Szmit, Sebastian
Kownacki, Łukasz
Torbicki, Adam

Powiązania:

https://bibliotekanauki.pl/articles/1065798.pdf

Data publikacji:

2014

Wydawca:

Medical Education

Tematy:

breast cancer
cardiotoxicity type II
trastuzumab

Opis:

Left ventricle systolic dysfunction manifesting during trastuzumab treatment is defined as cardiotoxicity type II. It is characterized by full reversibility after discontinuation of trastuzumab and cardiological pharmacological treatment. In a group of patients, however, systolic cardiac function does not fully recover. The reasons of this unfavorable prognosis are subject of heated discussion.

Źródło:

OncoReview; 2014, 4, 2; A62-68
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 34.

Tytuł:

Pathophysiological roles of ERα in the ER signaling mediated oncogenesis of breast cancer

Autorzy:

Abda Neja, Sultan

Powiązania:

https://bibliotekanauki.pl/articles/2040136.pdf

Data publikacji:

2020-12-30

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

breast, cancer
estrogen receptor alpha
oncogenesis

Opis:

Introduction. Estrogen receptors (ER) are members of nuclear receptors that act in the ER signaling pathway regulating the pathophysiology of hormone-responsive target cells including breast tissue. Aim. This detailled review literature was written on the pathophysiology of ER signaling as well as the effect altered ERα and associated pathway derangement in the oncogenesis of breast cancer. Material and methods. This review was performed according to systematic literature search of three major bibliographic databases (Scopus, PubMed, and Cochran). Analysis of the literature. In this pathway, estrogen receptor alpha (ERα) is a key estradiol-17β (E2) induced transcription factor that has been implicated in the initiation and development of the major fraction of breast cancers. Hence understanding the ERα-mediated ER signaling that results in alterations from normal phenotypic features of breast tissue to the oncogenic features of breast cancer is important. The oncogenic effect of ERα in ER signaling is driven by combinations of molecular assets within the cancer cells. Normally, the transcriptional activity of ERα is controlled by tight regulation of its protein level inside the cells. Altered stability and activity of ERα due to its phosphorylation, ubiquitination, glycosylation, sumoylation, and acetylation events can trigger oncogenic ER signaling. Conclusion. The function and activity of ERα is also modulated by its interaction with coregulators as well as crosstalk with oncogenic factors from other oncogenic pathways. These all events increase the complexity of the progression of ER+ breast cancer and its response to endocrine therapy

Źródło:

European Journal of Clinical and Experimental Medicine; 2020, 4; 289-302
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 35.

Tytuł:

Is there a rationale for aggressive breast cancer liver metastases resections in Polish female patients? Analysis of overall survival following hepatic resection at a single centre in Poland

Autorzy:

Kobryń, Eliza
Kobryń, Konrad
Wróblewski, Tadeusz
Kobryń, Krzysztof
Pietrzak, Radosław
Rykowski, Paweł
Ziarkiewicz-Wróblewska, Bogna
Lamparski, Krzysztof
Zieniewicz, Krzysztof
Patkowski, Waldemar
Krawczyk, Marek
Paluszkiewicz, Rafał

Powiązania:

https://bibliotekanauki.pl/articles/991146.pdf

Data publikacji:

2016

Wydawca:

Instytut Medycyny Wsi

Tematy:

liver metastases
breast cancer
liver surgery

Opis:

Introduction. Breast cancer (BC) makes up nearly 26% of malignant tumours worldwide and is the leading cause of cancerrelated deaths in European women. With approximately 18,000 new cases of BC diagnosed in Polish women annually, breast cancer liver metastasis (BCLM) is respectively an increasing issue. Recent data found in literature indicates improved survival following liver resection with systemic therapy. Objective. The aim of study was to evaluate surgical treatment in patients with isolated BCLM. Materials and method. During 2009–2013, a retrospective study was undertaken and 30 cases analysed. From nearly 2,000 liver resections performed, 11 female patients at the mean age of 59.18 years with BCLM were qualified for surgery. Results. The median time between primary and secondary treatment was 3.5 years (1–7). One patient (9.1%) presented an extrahepatic lesion – bone metastasis. The left lobe, right lobe and both lobes of the liver were affected, respectively, in 3 (27.3%), 4 (36.4%) and 4 (36.4%) patients. 5 patients (45.5%) presented single hepatic lesion, in contrast to the maximum number of lesions which equalled 6 in the right lobe. Average hospitalisation period was 13.27 days and discharge on the 11.3 postoperative day. One-year survival was 72.7% (8 patients); therefore, three-year survival was 36.4% (4 patients). Conclusions. Oncological centres should assess BCLM patients more openly and qualify them for hepatic resection along with adjuvant systemic treatment in order to improve overall survival. This, however, needs to be studied in a multicentre randomized trial.

Źródło:

Annals of Agricultural and Environmental Medicine; 2016, 23, 4
1232-1966

Pojawia się w:

Annals of Agricultural and Environmental Medicine

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 36.

Tytuł:

Quality of life during the first year after breast cancer resection

Autorzy:

Kulesza-Bronczyk, B.
Dobrzycka, B.
Piekut, K.
Terlikowski, R.
Mackowiak-Matejczyk, B.
Wojno, A.
Terlikowski, SJ.

Powiązania:

https://bibliotekanauki.pl/articles/1916396.pdf

Data publikacji:

2014

Wydawca:

Uniwersytet Medyczny w Białymstoku

Tematy:

Breast cancer
quality of life
questionnaires

Opis:

Introduction: Quality of life can be determined by a number of factors, including subjective perception of various spheres of health and health-unrelated factors. Purpose: To compare the quality of life of women who had breast cancer one month and one year after mastectomy, and to verify the usefulness of health-related quality of life (HRQoL) scales in early identification of patients having problems in various functional spheres. Materials and methods: The study included the group of 110 mastectomized women. Quality of life of the participants was estimated with EORTC QLQ-C30 and EORTC QLQ-BR23 questionnaires. Results: Global health status (QoL) determined with the aid of the EORTC QLQ-C30 questionnaire turned out to be significantly higher in women surveyed one year after mastectomy than in those examined one month after the surgery (74.23 vs. 58.33, p<0.001). Moreover, the two groups of patients differed significantly in terms of physical, cognitive, social and role functioning scores. Most of the symptoms assessed were resolved within a year after the breast cancer surgery. No significant intergroup differences were revealed with regard to emotional and socioeconomic functioning or future perspective scores. Conclusions: Quality of life of most mastectomized women improves considerably within one year after the surgery. The use of quality of life instruments can be useful in early postoperative identification of patients who score low on functional and symptom scales. Such patients require support and/or psycho-oncological treatment during the early postoperative period. Quality of life of breast cancer patients during the early postoperative period can be a predictor of this parameter in a longer-term perspective.

Źródło:

Progress in Health Sciences; 2014, 4, 1; 124-129
2083-1617

Pojawia się w:

Progress in Health Sciences

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 37.

Tytuł:

The assessment of the attitudes regarding medical information and participation in making medical decisions in patients with breast cancer

Autorzy:

Makara-Studzińska, Marta
Kowalska, Agnieszka
Urbańska, Anna

Powiązania:

https://bibliotekanauki.pl/articles/551598.pdf

Data publikacji:

2012

Wydawca:

Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych

Tematy:

breast cancer
medical information
medical decisions

Źródło:

Family Medicine & Primary Care Review; 2012, 1; 48-51
1734-3402

Pojawia się w:

Family Medicine & Primary Care Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 38.

Tytuł:

Cancer awareness and socioeconomic status are associated with mammography screening participation and early detection of breast cancer

Autorzy:

Badur, Włodzimierz
Donizy, Piotr
Szełemej, Joanna
Kornafel, Jan
Hałoń, Agnieszka
Matkowski, Rafał

Powiązania:

https://bibliotekanauki.pl/articles/551927.pdf

Data publikacji:

2014

Wydawca:

Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych

Tematy:

breast cancer
oncological awareness
screening
mammography

Źródło:

Family Medicine & Primary Care Review; 2014, 4; 329-332
1734-3402

Pojawia się w:

Family Medicine & Primary Care Review

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 39.

Tytuł:

The quality of life, general health, and pain sensations after treatment in the assessment of breast cancer patients

Autorzy:

Nowicki, Andrzej
Trybulska, Joanna
Rhone, Piotr

Powiązania:

https://bibliotekanauki.pl/articles/1035822.pdf

Data publikacji:

2018

Wydawca:

Medical Education

Tematy:

breast cancer
health
life quality
pain

Opis:

Introduction: General quality of life, health, and sensation of pain caused by cancer are connected with the physical, mental and social state of a human being. Aim of the study: The aim of the study is self-assessment of life quality, general health, and pain sensations in breast cancer patients after adjuvant therapy with chemo- and radiotherapy. Material and methods: The study was carried out in 2016 at the Professor Franciszek Łukaszczyk Oncology Clinic in Bydgoszcz. 56 women with breast cancer were qualified for the study, upon completion of treatment. Socio-demographic and clinical data was used, questions 29 and 30 from the QLQ C30 questionnaire, and the Memorial Pain Assessment Card. Results: Generally, the average self-assessment of health and life quality was 4.98 and 5.18 points, respectively. Age, education, marital status and the place of residence did not have any influence on the self-assessment of health and life quality (p > 0.05). 46 women (82.1%) did not take analgesics. Those patients who did not take analgesics assessed their health and life quality better, with the average scores of 5.3 and 5.63 points, respectively. The average for pain intensity was 2.05 on a 0–11 scale. Most women – 14 (25%) – assessed their mood as very good. The mood average was 2.91 points. Only the administration of analgesics influenced the mood score (p = 0.001). Conclusions: Women with breast cancer after radical treatment assess their health and life quality as good. Those not taking analgesics assess their health and life quality better and are decidedly in a better mood than those taking such medications. Socio-demographic factors do not influence self-assessment of health, life quality, or pain intensity.

Źródło:

OncoReview; 2018, 8, 2; 54-59
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 40.

Tytuł:

Anti-breast cancer potential of honey: a narrative review

Autorzy:

Qadirifard, Mohammad Sadegh
Fathabadi, Amirhossein
Hajishah, Hamed
Gholami, Kosar
Abbasi, Mohammadmehdi
Sami, Nafiseh
Zo, Mostafa Mahmoudi
Kadkhodaei, Fateme
Sina, Mahla
Ansari, Arina
Rahimi, Zahra
Deravi, Niloofar

Powiązania:

https://bibliotekanauki.pl/articles/2047807.pdf

Data publikacji:

2022-03-31

Wydawca:

Medical Education

Tematy:

honey
breast cancer
anticancer
complementary medicine

Opis:

Cancer is responsible for the death of millions of people all around the world. Among the large group of cancers, the prevalence of breast cancer is highest in women. Therapeutic interventions, including removal surgery, radiation therapy, hormone therapy, and chemotherapy which is largely used, may cause adverse effects on the quality of patients’ life. This fact has encouraged researchers to find natural substances such as honey to overcome harmful effects. Nowadays, honey is recommended for plenty of abnormalities because of its antioxidant, anti-inflammatory, and antimicrobial properties. Various studies have been conducted to explore the anticancer benefits of different types of honey from different origins. In this review, we are going to summarize in-vitro, animal, and human studies on the anti-breast cancer potential of honey.

Źródło:

OncoReview; 2022, 12, 1; 5-15
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 41.

Tytuł:

Principles of follow-up assessments in patients with breast cancer after radical treatment

Autorzy:

Hodorowicz-Zaniewska, Diana
Herman, Krzysztof

Powiązania:

https://bibliotekanauki.pl/articles/1393556.pdf

Data publikacji:

2017

Wydawca:

Index Copernicus International

Tematy:

breast cancer
treatment follow-up
recommendations

Opis:

A follow-up assessment plan after radical treatment is a part of a comprehensive approach to treating patients with breast cancer. Because breast cancer is the most frequent cancer both worldwide and in Poland, adequate follow-up is important not only for patients but also for economic reasons. Herein, we review current recommendations for follow-up assessments in patients with breast cancer. The main aim of such assessment is detection of early recurrence or tumor presence in the other breast, observation of long-term treatment complications, and creation of multidisciplinary infrastructure that will allow to reduce the risk of recurrence and alleviate physical, mental, and social consequences of treatment.

Źródło:

Polish Journal of Surgery; 2017, 89, 3; 36-39
0032-373X
2299-2847

Pojawia się w:

Polish Journal of Surgery

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 42.

Tytuł:

HER2-positive breast cancer -a vailable anti-HER2 therapies and new agents under investigation

Autorzy:

Zielinska, M.
Zarankiewicz, N.
Kosz, K.
Kuchnicka, A.
Cisel, B.

Powiązania:

https://bibliotekanauki.pl/articles/2097840.pdf

Data publikacji:

2020

Wydawca:

Instytut Medycyny Wsi

Tematy:

breast cancer
targeted therapies
HER2-positive breast cancer
HER2-targeting treatment
anti-HER2 drugs

Opis:

Introduction and objectives. Breast cancer (BC) is the most common malignancy and the leading cause of cancer death among women. About 15–20% of all BCs are HER2-positive. Proper assessment of HER2 status is crucial to choose appropriate treatment. The review summarizes data on anti-HER2 drugs used to treat HER2-positive BC and provides basic information on new agents under investigation. Brief description of the state of knowledge. Specific HER2-targeting drugs are available or are being evaluated in clinical trials. Anti-HER2 agents include: monoclonal antibodies, tyrosine kinase inhibitors, antibody-drug conjugates, bispecific antibodies, PI3K/AKT/mTOR inhibitors and heat shock protein 90 inhibitors, HER2-targeting vaccines and CDK4/6 inhibitors. The advent of anti-HER2 therapies increased the time of progression free survival and overall survival in BC patients. Results. Final analysis of the CLEOPATRA trial shows that the combination of trastuzumab, pertuzumab and taxane significantly improved outcomes in metastatic HER2-positive BC and it is currently preferred first-line treatment. The recommended second-line treatment is based on trastuzumab emtansine or on the combination of lapatinib and capecitabine. Some promising agents such as margetuximab or trastuzumab deruxtecan are still under investigation. Conclusions. Anti-HER2 directed treatment undoubtedly improves outcomes among patients with HER2-positive BC. Access to drugs such as trastuzumab, pertuzumab, lapatinib and T-DM1 improves prognosis even in patients with advanced disease. Further studies and clinical trials on novel anti-HER2 therapies are required. Nevertheless, BC treatment is becoming more effective and, hopefully, one day it may be possible to cure patients even with metastases.

Źródło:

Journal of Pre-Clinical and Clinical Research; 2020, 14, 2; 44-48
1898-2395

Pojawia się w:

Journal of Pre-Clinical and Clinical Research

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 43.

Tytuł:

Aspects of Post-Traumatic Stress Disorder symptomatology in patients with breast cancer: a review of prevalence, risk and mediating factors

Autorzy:

van Oers, Helena

Powiązania:

https://bibliotekanauki.pl/articles/1065168.pdf

Data publikacji:

2019

Wydawca:

Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN

Tematy:

Breast cancer
PTSD
distress
stress
subsyndromal PTSD

Opis:

It is widely accepted that a cancer diagnosis is a stressful and often traumatic experience for patients. Stress as a psychological side-effect of diagnosis has been well-researched. However, it is also possible that the life changing and potentially life-threatening aspects of disease may lead to symptoms of Post-Traumatic Stress Disorder (PTSD), including heightened anxiety, intrusive and distressing thoughts, avoidance of reminders of the trauma and sleeping disturbances. These symptoms may be of short duration but studies show that is possible for patients to live with PTSD for years after diagnosis and treatment. Even if not all the criteria for a full PTSD diagnosis are present, subthreshold or subsyndromal PTSD has been shown to cause significant distress and affect the quality of life of breast cancer patients. Given that with earlier diagnoses and ever more effective treatment interventions, the number of women who survive cancer and whose survival intervals are longer, identification, monitoring and treatment of patients living with PTSD becomes ever more important.

Źródło:

World Scientific News; 2019, 120, 2; 266-274
2392-2192

Pojawia się w:

World Scientific News

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 44.

Tytuł:

Cytotoxicity of PP(Arg)2- and PP(Ala)2(Arg)2-based photodynamic therapy and early stage of apoptosis induction in human breast cancers in vitro

Autorzy:

Nowak-Stępniowska, Agata
Wiktorska, Katarzyna
Małecki, Maciej
Milczarek, Małgorzata
Lubelska, Katarzyna
Padzik-Graczyk, Alfreda

Powiązania:

https://bibliotekanauki.pl/articles/1039664.pdf

Data publikacji:

2012

Wydawca:

Polskie Towarzystwo Biochemiczne

Tematy:

photodynamic therapy
breast cancer
transmembrane mitochondrial potential

Opis:

Mitochondria are cell energetic centers where ATP is produced. They also play a very important role in the PDT as intracellular sites of photosensitizer localization. Photosensitizers gathering in mitochondria (like porphyrin derivatives used in this work) are more effective in tumor cell destruction. Moreover, it was assumed that di-amino acid substituents attached to porphyrin ring will strengthen the effectivity of interaction with membrane receptors of examined cells. MTT assay was performed to investigate the influence of PP(Arg)2 and PP(Ala)2(Arg)2-based PDT on breast cancer cell viability for 24 h, 48 h and 120 h after cell irradiation. Then the influence of PP(Ala)2(Arg)2- and PP(Arg)2-mediated PDT on early mitochondrial apoptosis induction via measurements of the transmembrane mitochondrial potential changes was examined. Results showed that lower energy doses and maximal nontoxic photosensitizer doses of PP(Ala)2(Arg)2 and PP(Arg)2 applied in PDT can imply apoptotic cell death. It was confirmed that modification of the protoporphyrin IX by attaching two alanine substituents raised the efficiency of photodynamic therapy.

Źródło:

Acta Biochimica Polonica; 2012, 59, 4; 603-611
0001-527X

Pojawia się w:

Acta Biochimica Polonica

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 45.

Tytuł:

Educational programme of Early Breast Cancer Detection in 40-year-old female inhabitants from Cracow, as an element of a preventive treatment of complications requiring oncological rehabilitation
Program Edukacyjny Wczesnego Wykrywania Raka Piersi u 40-letnich mieszkanek miasta Krakowa jako element profilaktyki powikłań wymagających rehabilitacji onkologicznej

Autorzy:

Łabuzek, Monika
Kołodziejski, Leszek S

Powiązania:

https://bibliotekanauki.pl/articles/1966255.pdf

Data publikacji:

2014

Wydawca:

Akademia Wychowania Fizycznego im. Bronisława Czecha w Krakowie

Tematy:

breast cancer
Education
Mammography screening
prevention
Rehabilitation

Opis:

Introduction: Breast cancer is the most common malignant tumour among women in Poland, with a dynamically increasing incidence rate. At present, one-half of breast cancer cases are diagnosed at the stage of high locoregional advancement, which leads to common radical mastectomies. These procedures are the cause of the most serious complications, i.e. restricted mobility of the glenohumeral joint and lymphoedema of the upper limb, which usually require rehabilitation.Objective: An evaluation of the attendance and effectiveness of detecting suspicious breast lesions in 40-year-old female inhabitants of Kraków who were personally invited to take part in the Educational Programme of Early Breast Cancer Detection (EPEBCD). This study assumes that increasing the level of oncological education amongst women should result in high attendance in screening, which would lead to detection of breast cancer at earlier stages. In these cases, effective methods of breast-conserving therapy are used, which carry a minimal risk of complications that require rehabilitation.Material and methods: The subject of the analysis was a group of 19,773 female inhabitants of Kraków who took part in the EPEBCD between 2003 and 2008. The group consisted of 4723 women aged 40 years who were personally invited to take part in the Programme, and 15,010 other women who volunteered for the research. The percentage of suspicious lesions discovered in physical and mammographic examinations in both groups was analysed. In the statistical analysis, the stratum weight was examined, using a two-tailed test and the STATISTICA 6.0 program. The significance level α < 0.05 was assumed.Results: The attendance rate of 40-year old women who were sent personal invitations was similar in each year (2003 to 2008) and, on average, accounted for 24.4%, which was half of the assumed attendance. It demonstrates that the level of oncological education among young women is low. Breast cancer awareness increased with age and resulted in voluntary participation of older women in screening programmes. The percentage of suspicious changes detected by a physical examination among the 40-year-old women invited personally (Group 1; 0.49%) did not differ significantly from the “before screening” group (Group 2, aged 41 to 49; 0.47%) and even from the “screening” group (Group 3, aged 50 to 69; 0.45%). Only in the “after screening” group of the oldest women (Group 4, over 69), the percentage (1.57%) was significantly higher (p < 0.001). The percentage of suspicious changes detected by mammography did not differ significantly in the group of 40-year-old women (Group 1; 3.58%) and in the “before screening” group (Group 2; 4.11%; Groups 1 and 2, p > 0.05). Significant differences were only found in the “before screening” Group 2 and “after screening” Group 4 (p < 0.001). The percentage of suspicious changes identified by mammography did indeed increase with age, though this was only a marginal increase, at the level of tenths of a percent. Only in the oldest group (Group 4), this percentage (5.16%) was significantly higher than in the other research groups.Conclusions: The much higher percentage of suspicious breast lesions discovered by mammography in comparison with those discovered in a physical examination demonstrates a low level of breast cancer advancement in most cases, which can be treated by means of breast-conserving therapy. Dissemination of educational and screening programmes will help to increase the percentage of early detected breast cancer cases which, after breast-conserving therapy, will not constitute a risk of serious complications requiring rehabilitation.

Źródło:

Medical Rehabilitation; 2014, 18(1); 5-14
1427-9622
1896-3250

Pojawia się w:

Medical Rehabilitation

Dostawca treści:

Biblioteka Nauki

/5

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Skocz do pozycji: 46.

Tytuł:

Ocena kardiotoksyczności u pacjentek z rakiem piersi leczonych trastuzumabem*
Evaluation of cardiotoxicity in trastuzumab-treated women with breast cancer

Autorzy:

Sidło-Stawowy, Agata
Sawicka, Magdalena
Kubeczko, Marcin
Sikoń, Ewelina
Piszko, Justyna
Maruszczyk, Wojciech
Stando, Rafał
Bracik, Joanna

Powiązania:

https://bibliotekanauki.pl/articles/1038053.pdf

Data publikacji:

2013

Wydawca:

Śląski Uniwersytet Medyczny w Katowicach

Tematy:

kardiotoksyczność
rak piersi
trastuzumab
cardiotoxicity
breast cancer

Opis:

INTRODUCTION Breast cancer is the most frequent malignancy in women in Poland. Overexpression of the HER2 receptor positively correlates with the aggressiveness of the disease. Trastuzumab, a humanized monoclonal antibody against HER2, radically improves the prognosis in such patients. However, its main side effect is cardiotoxicity. The aim of this study is to evaluate the cardiotoxicity in trastuzumab-treated patients. MATERIALS AND METHODS The cases of 19 women treated in the Department of Internal Medicine and Oncologic Chemotherapy Medical University of Silesia in Katowice in the period of 2010–2011 were retrospectively analyzed. RESULTS The median age at the time of diagnosis – 57 years, pathology: invasive ductal carcinoma in 17, invasive lobular carcinoma in 2 patients. Overexpression of HER2 was observed in all the cases. Trastuzumab was administered to 16 of them after previous therapy with antracyclines and/or taxan; the median total antracycline dose was 680 mg. Moreover, 13 patients were subjected to radiotherapy; the median total dose was 50 Gy. In 3 patients, trastuzumab and chemotherapy was used in the management of metastasized disease. The median time between the administration of trastuzumab and anthracyclines was 3 months. The median number of cycles was 10. Before administration of the drug, ECG and echocardiography were performed along with ejection fraction (EF) assessment. Before and after therapy the median EF was 65% and 61%, respectively. The therapy was withheld in 1 patient because of a decrease in EF to 40%. CONCLUSIONS The treatment with trastuzumab was well tolerated. In most patients, we did not observe a significant decrease in EF. However, the cases should be followed up to detect delayed cardiotoxicity.
WSTĘP Rak piersi to najczęstszy nowotwór złośliwy u kobiet w Polsce. W praktyce klinicznej ważne jest określenie ekspresji receptorów, w tym dla naskórkowego czynnika wzrostu typu 2 (HER2) na komórkach nowotworowych. Gdy komórki te wykazują wzmożoną ekspresję HER2, przebieg choroby jest agresywniejszy. Trastuzumab, humanizowane przeciwciało monoklonalne przeciw HER2, znacząco poprawia rokowanie. Jednak terapia taka nie jest pozbawiona działań niepożądanych, w tym kardiotoksyczności. Celem pracy była ocena kardiotoksyczności leczenia trastuzumabem u pacjentek z rakiem piersi. MATERIAŁ I METODY Dokonano retrospektywnej analizy historii chorób 19 kobiet leczonych w Klinice Chorób Wewnętrznych i Chemioterapii Onkologicznej Śląskiego Uniwersytetu Medycznego w Katowicach w latach 2010–2011. WYNIKI Mediana wieku w chwili rozpoznania – 57 lat, typ histologiczny: rak przewodowy naciekający u 17, rak zrazikowy naciekający u 2 pacjentek. Nadekspresję HER2 stwierdzono u wszystkich 19 kobiet, u 16 z nich zastosowano trastuzumab po wcześniejszym leczeniu upełniającym antracyklinami i/lub taksanami – mediana sumarycznej dawki antracyklin 680 mg. U 13 pacjentek dodatkowo przeprowadzono radioterapię – mediana dawki sumarycznej 50 Gy. U 3 pacjentek podano trastuzumab oraz chemioterapię w leczeniu rozsianej choroby nowotworowej. Mediana czasu włączenia trastuzumabu po antracyklinach wyniosła 3 miesiące. Liczba cykli: mediana 10. Przed włączeniem leku wykonano badanie EKG i czynnościowe serca z oceną frakcji wyrzutowej (EF). Mediana EF przed rozpoczęciem leczenia: 65%, po leczeniu: EF 61%. U jednej pacjentki przerwano leczenie z powodu obniżenia EF do 40%. WNIOSKI Leczenie trastuzumabem było dobrze tolerowane. U większości pacjentek nie obserwowano znamiennego obniżenia EF wymagającego odstawienia leku. Badana grupa wymaga jednak badań czynnościowych serca również po odstawienia trastuzumabu w celu wykrycia późnych powikłań kardiotoksycznych.

Źródło:

Annales Academiae Medicae Silesiensis; 2013, 67, 2; 123-127
1734-025X

Pojawia się w:

Annales Academiae Medicae Silesiensis

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 47.

Tytuł:

Efficacy and safety of non-pegylated liposomal doxorubicin in metastatic breast cancer therapy

Autorzy:

Wójcik, Elżbieta
Kufel-Grabowska, Joanna
Gierba-Tomczyk, Joanna

Powiązania:

https://bibliotekanauki.pl/articles/1062503.pdf

Data publikacji:

2017

Wydawca:

Medical Education

Tematy:

breast cancer
non-pegylated liposomal doxorubicin
treatment

Opis:

Breast cancer is the most frequently diagnosed female cancer in Poland (over 17,500 women). Anthracyclines have become one of the most important drugs in breast cancer systemic treatment. In the treatment of metastatic disease combination chemotherapy with doxorubicin provides the objective response rate of 60–85%, and the median time of progression-free survival is about 12 months. Non-pegylated liposomal doxorubicin (NPLD) in combination with cyclophosphamide is associated with a lower risk of cardiotoxicity, higher efficacy and more favourable toxicity profile as compared with conventional anthracycline regimes. Two cases of females patients treated with NPLD described in this article demonstrate the importance of the choice of chemotherapy, professional monitoring, early detection and treatment of adverse effects. Non-pegylated liposomal doxorubicin ordained in systemic treatment of stage IV breast cancer prolongs survival and enhances the quality of life. It is a reasonable option for palliative therapy.

Źródło:

OncoReview; 2017, 7, 4; 162-167
2450-6125

Pojawia się w:

OncoReview

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 48.

Tytuł:

Evaluation of the quality of life of women treated due to breast cancer using amputation or breast conserving surgery in the early postoperative period

Autorzy:

Nowicki, Andrzej
Licznerska, Bernardeta
Rhone, Piotr

Powiązania:

https://bibliotekanauki.pl/articles/1395600.pdf

Data publikacji:

2015-04-01

Wydawca:

Index Copernicus International

Tematy:

breast cancer
surgical treatment
quality of life

Opis:

Selection of the treatment method in breast cancer patients and its consequences may affect their quality of life through somatic, psychical, and social factors. The aim of the study was early evaluation of the quality of life of women after mastectomy vs. breast conserving surgery. Material and methods. The study included 100 women aged 31 to 79 years (mean: 57) who underwent surgery due to breast cancer (amputation: 52; breast conserving surgery: 48 women) at the Cancer Centre in Bydgoszcz in 2014. The QLQ C-30 and QLQ BR-23 questionnaires were used to evaluate the quality of life of the patients 3 months after surgery. Results. In the Global Health Status/QoL domain, the mean score for women after amputation and breast conserving surgery was 49 and 53, respectively; for Physical Functioning, the scores were 70 and 75, and for Role Functioning, 62 and 68, respectively. For Cognitive Functioning, the mean score was 74 and 73; for Emotional Functioning - 62 and 68, and for Social Functioning 64 and 60, respectively. The difference in the arm symptoms domain was significant at 46 and 33 points, respectively (p = 0.004). The patients treated with breast conserving surgery had a better body image than women after amputation - the mean score was 52 and 66, respectively (p = 0.01). Conclusions. With respect to Global Health Status/QoL and Physical Functioning, the quality of life of women in the early postoperative period was similar in women after breast amputation and those who underwent breast conserving surgery. Patients treated with breast conserving surgery had a better score for body image, while those who underwent amputation more often suffered from arm symptoms, such as pain, oedema, and problems with raising of the limb.

Źródło:

Polish Journal of Surgery; 2015, 87, 4; 174-180
0032-373X
2299-2847

Pojawia się w:

Polish Journal of Surgery

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 49.

Tytuł:

Practicing Sport in the Age Group 21-34 and the Risk of Breast Cancer - Analysis of the Results of a Retrospective Study

Autorzy:

Kładna, Aleksandra
Skołozdrzy, Tomasz
Wojciechowski, Jan
Tadaj, Bartosz
Kawka, Martyna
Kellas, Aleksandra

Powiązania:

https://bibliotekanauki.pl/articles/24202860.pdf

Data publikacji:

2023

Wydawca:

Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego

Tematy:

breast cancer
retrospective study
physical activity
prevention

Opis:

Breast cancer is the most common malignant tumor in women, so it is important to study the factors that can protect against it. One of them is physical activity, which has become the area of our interest, especially the practice of sports by women aged between 21 and 34. The aim of this retrospective study was to check how practice of sport in the age group of 21-34 in women from the research group diagnosed with breast cancer and in the control group (healthy women from families burdened with this cancer) influences the risk of developing breast cancer. The study showed that healthy women from families with a burden of breast cancer practiced sports in the age range 21-34 more frequently and intensively than women who had a history of breast cancer. (Sport 1-highest intensity P = 0.002 Sport 2-medium intensity P < 0.001 Sport 3-the lowest intensity P < 0.001.) It can be concluded that practicing sport in the age group of 21-34 is an important factor in the prevention of breast cancer, although the influence of other protective factors in women from the control group cannot be ruled out.

Źródło:

Central European Journal of Sport Sciences and Medicine; 2023, 43; 53-61
2300-9705
2353-2807

Pojawia się w:

Central European Journal of Sport Sciences and Medicine

Dostawca treści:

Biblioteka Nauki

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Skocz do pozycji: 50.

Tytuł:

Health behaviors of patients after breast cancer surgery in the Podkarpackie voivodeship

Autorzy:

Pusz-Sapa, Aleksandra
Gaweł, Greta
Sobczyk, Joanna
Wojtasik, Aneta
Król, Małgorzata
Misiewicz, Emilia
Lidwin, Barbara

Powiązania:

https://bibliotekanauki.pl/articles/454741.pdf

Data publikacji:

2017

Wydawca:

Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego

Tematy:

breast cancer
health behaviors
diet
physical activity

Opis:

Aim. An evaluation of lifestyle changes (physical activity, diet) in patients after breast cancer surgery. Materials and method. 200 women after breast cancer surgery were surveyed. The respondents were asked whether the surgery caused a change in their diet and physical activity. An analysis was performed concerning the education, place of residence and age of the respondents. Results. Prior to being diagnosed with breast cancer, about one third of the respondents were concerned about their diet and physical activity. After the surgery more than a half of the respondents were concerned about a healthy lifestyle. Women below 50 years old with higher education, who live in a city, were concerned about their diet and physical activity both before and after surgery. Conclusions. As a result of the breast cancer surgery, lifestyle changes were most often found in women aged 50-69 years old with higher education who lived in a city. Statistical relevance of the results was noted.

Źródło:

European Journal of Clinical and Experimental Medicine; 2017, 4; 310-314
2544-2406
2544-1361

Pojawia się w:

European Journal of Clinical and Experimental Medicine

Dostawca treści:

Biblioteka Nauki

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