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Tytuł:
Antibiotic consumption pattern in a single neonatal care unit
Autorzy:
Nitsch-Osuch, Aneta
Marciniak, Anna
Życińska, Katarzyna
Wardyn, Kazimierz
Powiązania:
https://bibliotekanauki.pl/articles/552499.pdf
Data publikacji:
2013
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
antibiotics
consumption
neonatal unit
Źródło:
Family Medicine & Primary Care Review; 2013, 4; 552-555
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Utilization of penicillinase-producing Micrococcus strains in the technology of fermented milk products. I. Decomposition of penicillin in milk by selected Micrococcus strains
Możliwości wykorzystania penicylinazo-dodatnich szczepów rodzaju Micrococcus w technologii fermentowanych produktów mleczarskich. I. Rozkład penicyliny w mleku przez wybrane szczepy rodzaju Micrococcus
Autorzy:
Czarnocka-Roczniakowa, B.
Maciejska, A.
Powiązania:
https://bibliotekanauki.pl/articles/1398369.pdf
Data publikacji:
1985
Wydawca:
Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie
Tematy:
Micrococcus
penicillinase
antibiotics in milk
Opis:
Three of the isolated Micrococcus strains demonstrated a high and constant rate of decomposition of penicillin in milk. The strains decomposed penicillin in concentrations ranging from 0.1 to 6.0 IU/cm³ in 2-4 h.
Badano zmiany zawartości penicyliny w .mleku pod wpływem wyselekcjonowanych penicylinazo-dodatnich szczepów ziarenkowców. Stałą i wysoką aktywnością rozkładu antybiotyku charakteryzowały się szczepy: Micrococcus sp. 51p, 64p i 26p. Pozostałe szczepy ziarenkowców charakteryzowały się niższą i zmienną aktywnością rozkładu penicyliny.
Źródło:
Acta Alimentaria Polonica; 1985, 11, 4; 461-467
0137-1495
Pojawia się w:
Acta Alimentaria Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Will antiseptics become the standard in ophthalmology in the future?
Autorzy:
Szumny, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/23202401.pdf
Data publikacji:
2023-09-30
Wydawca:
Medical Education
Tematy:
antiseptics
povidone-iodine
chlorhexidine
antibiotics
Opis:
Antiseptics are a group of substances widely used in ophthalmology for many years. They are well established, especially in the prevention of perioperative infections. For decontamination in ophthalmology, a 5% povidone-iodine solution is used as a standard for the conjunctival sac. It is considered the most effective preoperative antisepsis. In patients with an allergy to iodine, a solution of 0.05% chlorhexidine is recommended. There are also attempts to use other antiseptics and antibiotics for perioperative prophylaxis. Recently, there has also been interest in potential use antiseptics for the treatment of conjunctivitis.
Źródło:
OphthaTherapy; 2023, 10, 3; 190-194
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The Presence of Metals and Antibiotics Resistant Bacteria in Arable Manure Soils
Autorzy:
Erdem, B.
Dayangaç, A.
Şahin, İ.
Powiązania:
https://bibliotekanauki.pl/articles/1031124.pdf
Data publikacji:
2017-09
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
heavy metals
antibiotics
resistance
manure soils
Opis:
Heavy metals and antibiotics resistance are intense public interest owing to their pollution in the environment and potential deleterious effects on human health. A total of 15 isolates of Bacillus subtilis, Bacillus cereus, Pseudomonas aeruginosa and Escherichia coli (50 manure garden soils) were tested for their resistance against certain heavy metals and antibiotics. Minimum inhibitory concentrations of Pb²⁺, Co²⁺, Cu²⁺, and Zn²⁺ for each isolate were also determined. B. subtilis, B. cereus, P. aeruginosa and E. coli exhibited high tolerance to minimum inhibitory concentrations of 3,200 μg/ml for Pb²⁺, 400 μg/ml for Cu²⁺ and Co²⁺, and 100 μg/ml for Zn²⁺ in agar plates. All the isolates were highly resistant to lead and they showed 100% growth in 3,200 μg/ml concentration. It was observed that all isolates were resistant to a wide range of antibiotics namely clindamycin, ceftazidime, aztreonam and vancomycin.
Źródło:
Acta Physica Polonica A; 2017, 132, 3; 570-571
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Bactericidal TiO2 layers doped with Cu, Zn, and ZnO
Autorzy:
Jakubowski, W.
Frankowski, P.
Jastrzębska, A.
Celigowska, A.
Frąckiewicz, P.
Walkowiak, B.
Powiązania:
https://bibliotekanauki.pl/articles/284240.pdf
Data publikacji:
2017
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
chemical antimicrobial substances
bacterial biofilms
antibiotics
Źródło:
Engineering of Biomaterials; 2017, 20, no. 143 spec. iss.; 30
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Knowledge and attitudes of parents towards responsible antibiotic therapy in respiratory system infections
Autorzy:
Hreńczuk, M.
Rosińska, K.
Małkowski, P.
Powiązania:
https://bibliotekanauki.pl/articles/2087693.pdf
Data publikacji:
2020
Wydawca:
Uniwersytet Opolski. Instytut Nauk o Zdrowiu
Tematy:
antibiotics
antibiotic resistance
knowledge
practice
parents
Opis:
Background: Testing general knowledge on antibiotics, and the rational application of them in practice, is very important in order to understand the need to educate society and the irreversible problem of antibiotic resistance. Aim of the study: The aim of the study was to analyze the knowledge and practice of parents regarding responsible antibiotic therapy in respiratory infections. Material and methods: This study was carried out among 317 parents aged 22-61 (M = 34.74; SD = 6.31). The diagnostic survey method was applied, and the research tool was a survey questionnaire. Statistical analysis was performed using the IBM SPSS Statistics 25.0 statistical package. Statistical significance was set at p < 0.05. Results: Viruses were identified as the most frequent cause of respiratory tract infection by respondents (n = 245, 77.3%). According to 91.2% of participants, antibiotics are used against a bacterial infection. Almost all (n = 315, 99.4%) respondents are of the opinion that antibiotics ought to be applied after a medical examination if they are definitely recommended, 97.5% (n = 309) believed that taking antibiotics could not be stopped at any time, whereas 10.4% (n = 33) used antibiotics without contacting a physician. 15.1% (n = 48) of the respondents used the antibiotics left over from previous treatment. Conclusions: The respondents possess knowledge concerning indications for antibiotic treatment and on their rational use, but unfortunately, not everyone uses this knowledge in practice.
Źródło:
Medical Science Pulse; 2020, 14, 3; 18-24
2544-1558
2544-1620
Pojawia się w:
Medical Science Pulse
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antibiotic resistance of bacteria and incidence of carbapenamase-coding genes blaPER and blaGES in isolates from wastewater treatment plants
Autorzy:
Jendrzejewska, Natalia
Powiązania:
https://bibliotekanauki.pl/articles/1178215.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
antibiotics-resistant bacteria
genes
pollution
wastewater
Opis:
The increase in number of antibiotic resistant bacteria poses a serious environmental and health problem. The development of microbial resistance is intensified by the widespread use of antibiotics in medicine, veterinary, farming and aquaculture. The wastewater treatment plants receiving the wastewater from hospitals, slaughterhouses, farms, pharmaceutical industry and houses can be potential places of spreading of antibiotic resistant genes. The molecular mechanisms of the bacterial resistance, including the horizontal transfer of antibiotic resistant genes and the presence of mobile genetic elements can be responsible for the increase in antibiotic resistance during wastewater treatment. The aim of this study was to analyze the phenomenon of bacterial resistance to selected β-lactam antibiotics (ESBL) by detecting the genes that determine this resistance. The PCR method was used to analyze the occurrence of two genes: blaPER and blaGES in wastewater samples. It was revealed that the resistant/total bacteria ratio was significantly higher in the effluent compared with the influent wastewater. Genes blaPER and blaGES were isolated from several strains predominating in both aeration tank (5% and 20% respectively) and effluent wastewater (15% and 12% respectively).
Źródło:
World Scientific News; 2018, 93; 30-39
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
THE STUDY OF ADSORPTION AND DESORPTION OF ANTIBIOTICS ON THE SURFACE OF NANOPARTICLES
Autorzy:
Biernat, Paweł
Borak, Beata
Meler, Jan
Karolewicz, Bożena
Powiązania:
https://bibliotekanauki.pl/articles/895282.pdf
Data publikacji:
2018-10-31
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
silica
antibiotics
nanoparticles
adsorption
drug
carrier
Opis:
Nanotechnology is a field that is gaining more and more importance in the modern world. It uses a particle size of between a few dozen to a few hundred nanometers, or 10-9 meters. It is noted that the use of nanospheres (balls with a diameter of from several to several hundred nm) as carriers of drugs gives an opportunity for their controlled and sustained release. (1,2) Nanospheres as a potential drug carrier for sustained release may enhance the effectiveness of antibiotics. In order to examine the effects of antibiotics with nanospheres an attempt was made to deposit on them three drugs differing in chemical structure. These were chloramphenicol, gentamicin and ceftazidime. The aim of this study was to determine the degree of adsorption of the drug on the surface of nanospheres and to examine the process of desorption from the surface of silica nanoparticles. The results of the study indicate that in the case of chloramphenicol it is essentially a process of chemisorption, and for gentamicin and ceftazidime both physical and chemical adsorption, without there being any clearly defined relationship between this two processes. The purpose of the nanospheres as drug carriers is to obtain controlled and prolonged exposure to the drug. The amount of adsorbed substance depends primarily on its structure. Ceftazidime, as the compound with the highest number of double bonds, and a large number of groups to form hydrogen bonds (carbonyl groups, amino groups), adsorbed to the greatest extent.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 5; 1215-1222
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ventilator-associated pneumonia (VAP) caused by Acinetobacter baumannii in view of the microbial properties of the ESKAPE group in neighbouring countries - Poland and Ukraine
Autorzy:
Grochowalska, Aneta
Kozioł-Montewka, Maria
Oliynyk, Oleksandr
Krasij, Natalia
Powiązania:
https://bibliotekanauki.pl/articles/972522.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
resistance to antibiotics
VAP
ESKAPE
Acinetobacter baumannii
Opis:
The increase in the clinical threat of ESKAPE pathogens is associated with high virulence and the presence of numerous mechanisms of antimicrobial resistance. The above characteristics of pathogens affect therapeutic failures as well as cause prolongation and increase of the cost of its treatment. Objective. The aim of this study was to evaluate and analyze Acinetobacter baumannii strains in relation to the remaining bacteria from the ESKAPE group that induced pneumonia in mechanically ventilated patients in two neighboring countries. Materials and method. The study was retrospective. 335 clinical materials were analyzed, mainly bronchoalveolar lavage gained for microbiological screen. The analyzed patients were in intensive care units (ICU) in selected hospitals in 2013 –2015, in Poland (154 patients) and in Ukraine (181 patients). Results. In the analysis of etiological agents of VAP caused by ESKAPE strains, Gram negative bacteria were predominant in both countries although particular species occurred at different frequencies in Poland and Ukraine. Multi-resistant strains of Acinetobacter baumannii were more frequently cultured from patients in Poland (26.9%) compared to those from Ukraine (14.6%).
Źródło:
Journal of Pre-Clinical and Clinical Research; 2017, 11, 2; 111-115
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antibiotics in agriculture – application, threats and legal regulations
Autorzy:
Gawryjołek, Karolina
Powiązania:
https://bibliotekanauki.pl/articles/2148227.pdf
Data publikacji:
2021-12-30
Wydawca:
Instytut Uprawy Nawożenia i Gleboznawstwa – Państwowy Instytut Badawczy
Tematy:
antibiotics
animal farming
antibiotic resistance
environment pollution
Opis:
The discovery of the first antibiotic has become one of the most important medical advances. Since this time, a pe- riod of intensive research into antimicrobial substances has be- gun, which are also used in veterinary medicine and agricultural production. In animal production, antibiotics have therapeutic, as well as prophylactic and metaphylactic applications aimed at preventing bacterial diseases. They were also used as growth stimulants, which positively influenced, among others, for weight gain and more efficient use of feed. This form of antibiotic use in animal production was legally banned in 2006 in all European Union countries. In the cultivation of plants, antibiotics are also used to combat plant pathogens. The use of antibiotic agents has many consequences, both positive and negative. The most impor- tant risk of antibiotics overusing is the spread of antibiotic resist- ant bacteria. Another effect is environmental pollution and the contamination of agricultural products. Due to these factors, the use of antibiotics in agriculture is regulated by appropriate legal regulations.
Źródło:
Polish Journal of Agronomy; 2021, 47; 10-21
2081-2787
Pojawia się w:
Polish Journal of Agronomy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Simultaneous Adsorption of Ternary Antibiotics (Levofloxacin, Meropenem, and Tetracycline) by SunFlower Husk Coated with Copper Oxide Nanoparticles
Autorzy:
Ibrahim, Mohammed A.
Shaban, Mohammed Ali A.
Hasan, Yaseen Rashid
M-Ridha, Mohanad J.
Hussein, Haitham A.
Abed, Khalid M.
Mohammed, Sabah J.
Muhamad, Mohd Hafizuddin
Hasan, Hassimi Abu
Powiązania:
https://bibliotekanauki.pl/articles/2105287.pdf
Data publikacji:
2022
Wydawca:
Polskie Towarzystwo Inżynierii Ekologicznej
Tematy:
adsorption
antibiotics
neural network
wastewater
sustainable process
Opis:
In this study, a new adsorbent derived from sunflower husk powder and coated in CuO nanoparticles (CSFH) was investigated to evaluate the simultaneous adsorption of Levofloxacin (LEV), Meropenem (MER), and Tetracycline (TEC) from an aqueous solution. Significant improvements in the adsorption capacity of the sunflower husk were identified after the powder particles had been coated in CuO nanoparticles. Kinetic data were correlated using a pseudo-second-order model, and was successful for the three antibiotics. Moreover, high compatibility was identified between the LEV, MER, and TEC, isotherm data, and the Langmuir model, which produced a better fit to suit the isotherm curves. In addition, the spontaneous and exothermic nature of the adsorption process was crucial for transforming the three antibiotics into CSFH. The greatest CSFH adsorption capacity was in MER (131.83 mg/g), followed by TEC (96.95 mg/g), and LEV (62.24 mg/g). These findings thus indicate that CSFH is one of the most effective and efficient adsorbents to use for eliminating wastewater contaminated with antibiotic residue.
Źródło:
Journal of Ecological Engineering; 2022, 23, 6; 30--42
2299-8993
Pojawia się w:
Journal of Ecological Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of alkaloid berberine on the susceptibility of nontuberculous mycobacteria to antibiotics
Autorzy:
Puk, K.
Guz, L.
Powiązania:
https://bibliotekanauki.pl/articles/16539338.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
berberine
antibiotics
mycobacterium
NTM
minimum inhibitory concentration
Opis:
Nontuberculous mycobacteria (NTM) have recently emerged as important bacterial pathogens of both animals and humans. In this study, we aimed to evaluate the effect of a combination of ten antibiotics with an inhibitor of efflux pumps (EPI), i.e. berberine (BER), against 6 strains of NTM. Our results showed that the BER potentiated the anti-mycobacterial activities of the antibiotics. Overall, our findings show the importance of BER in increasing the efficacy of antibiotics in NTM.
Źródło:
Polish Journal of Veterinary Sciences; 2022, 25, 3; 479-481
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Factors, impacts and possible solutions of antibiotic resistance: Review article
Autorzy:
Geta, Kindu
Powiązania:
https://bibliotekanauki.pl/articles/1046544.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Antibiotic Resistance Bacteria
Antibiotics
Factors
Impacts
Solutions
Opis:
The discovery of antibiotics has helped to save the lives of an uncountable number of people. Unfortunately, their misuse and other related factors have led to the emergence and development of bacteria that are resistant to antibiotics. Antimicrobial resistance is one of the most serious threats to public health globally and threatens the ability to treat infectious diseases. The factors that contribute for the emergence and spread of antimicrobial resistance are complex non-prudent use of antibiotics in veterinary and human medicine is, in large part, responsible for the emergence of antibiotic resistance. Inappropriate prescription practices, inadequate education, poor drug quality, limited rapid diagnostic test facilities, poor hygiene, infection prevention and control practice are also other factors contribute for the emergence and spread of antimicrobial resistance. Due to the emergency of new resistant bacteria and decrease in efficiency of treating common infectious diseases, it results in failure of microbial response to standard treatment, leading to prolonged illness, higher expenditures for health care, and an immense risk of death. Considering these serious impacts of antibiotic resistance several solutions have been proposed including antibiotic stewardship, educational program, hygiene, infection prevention and control strategy, adapting rapid methods for detecting resistance bacteria as well as developing new antibiotics and alternative therapeutic agents.
Źródło:
World Scientific News; 2019, 138, 2; 225-247
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Treatment of conjunctivitis
Leczenie schorzeń spojówki
Autorzy:
Prost, Marek E.
Rymgayłło-Jankowska, Beata
Powiązania:
https://bibliotekanauki.pl/articles/2046659.pdf
Data publikacji:
2021-12-31
Wydawca:
Medical Education
Tematy:
conjunctivits
treatment
antibiotics
zapalenie spojówek
leczenie
antybiotyki
Opis:
The aim of the publication is to present a description of a few clinical cases of conjunctivitis, in which treatment with the use of ophthalmic preparations that have existed for a long time has proved to be an effective form of therapy.
Celem publikacji jest przedstawienie opisu kilku przypadków klinicznych zapalenia spojówek, w których leczenie za pomocą istniejących od dawna preparatów okulistycznych okazało się skuteczne.
Źródło:
OphthaTherapy; 2021, 8, 4; 249-252
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The relationship between antibiotic therapy in early childhood and the symptoms of allergy in children aged 6–8 years — the questionnaire study results
Autorzy:
Raciborski, Filip
Tomaszewska, Aneta
Komorowski, Jarosław
Samel-Kowalik, Piotr
Białoszewski, Artur Z.
Walkiewicz, Artur
Lusawa, Adam
Szymański, Jakub
Opoczyńska, Dagmara
Drużba, Michał
Borowicz, Jacek
Lipiec, Agnieszka
Kapalczynski, Wojciech J.
Samoliński, Bolesław
Powiązania:
https://bibliotekanauki.pl/articles/2180075.pdf
Data publikacji:
2012-09-01
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
asthma
allergy
antibiotics
epidemiology
prevalence
risk factors
Opis:
Introduction: Studies based on the ISAAC questionnaire suggest a correlation between the use of antibiotics and the prevalence of asthma and allergy in children aged 6-7 years. The number of courses of antibiotic therapy is an important factor. Objectives: To investigate the relationship between the use of antibiotics during the fi rst years of life and the prevalence of allergy and asthma among children (aged 6-8 years) in the urban population of Poland. Materials and Methods: A survey-based study with a self-completed questionnaire. The respondents were parents of children aged 6-8 years living in Warszawa, Poland. 1461 completed questionnaires were collected. Results: Asthma was declared in 4.3% of the children. Wheezing and/or sibilant rhonchi within 12 months before the study was observed in 13.5% of the cases. Asthma medication was taken by 21.8% of the children. Allergic rhinitis was declared in 18.7% of the children. Problems with sneezing, rhinorrhea, and nasal congestion not associated with cold or fever were observed in 40.7% of the children. The a nalysis of the odds ratios between the use of antibiotics and the symptoms of allergic diseases revealed a clear correlation. The highest odds ratio was observed between the completion of over three courses of antibiotic therapy prior to the age of 12 months and the declaration of one of the following: asthma (OR = 5.59, 95% CI: 2.6-12.01), wheezing and/or sibilant rhonchi (OR = 4.68, 95% CI: 3.01-7.27) and taking medicines for breathlessness (OR = 5.12, 95% CI: 3.42-7.68). Conclusions: There is a direct relationship between antibiotic use in the fi rst 3 years of life and asthma and allergy symptoms in children aged 6-8 years old.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2012, 25, 4; 470-480
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Phytochemical screening and in vitro antimicrobial properties of Annona muricata extracts against certain human pathogens
Autorzy:
Oluyege, J.O.
Orjiakor, Paul Ikechukwu
Badejo, O.E.
Powiązania:
https://bibliotekanauki.pl/articles/135020.pdf
Data publikacji:
2019
Wydawca:
Akademia Morska w Szczecinie. Wydawnictwo AMSz
Tematy:
Annona muricata
pathogens
bacteria
fungi
antibiotics
medicinal plants
Opis:
All over the world, the use of medicinal plants is gaining more acceptability due to the possibility of discovering novel drugs from them and solving the problem of antimicrobial resistance associated with conventional antibiotics. The phytochemical composition and antimicrobial properties of crude extracts of the leaves, stems, and bark of Annona muricata were evaluated on Escherichia coli, Staphylococcus aureus, and Salmonella typimurium, while the antifungal properties were evaluated against Candida albicans and Candida tropicalis. The Agar well method was used for the study. At concentrations of 150 mg/ml and 300 mg/ml, inhibitory effects were observed on E. coli and S. aureus, with a visible zone of inhibition ranging from 15 mm to 21 mm respectively, and with respect to N- hexane, an antimicrobial activity range of 5 mm to 20 mm, for the leaf extract, which shows effective antimicrobial action against E. coli and S. aureus. Hot water extracts were observed to possess more bioactive compounds compared to organic solvent extracts, and exhibit higher ranges of activity against the tested bacterial species. All extracts exhibited low anti-fungal activity in the range of 8 mm to 15 mm. The phytochemical screening of the extracts of different parts of A. muricata revealed the presence of secondary metabolites such as tannins, alkaloids, saponins, flavonoids, steroids, and cardiac glycosides. The antimicrobial activity of the extracts was compared with a standard antibiotic, ketoconazole, and with ampicillin, which served as the controls). The results showed that A. muricata can be used as an anti-bacterial substance, since it shows broad spectrum activity against a range of bacteria responsible for the most common bacterial illnesses. Further research will be necessary to ascertain its full spectrum of efficacy.
Źródło:
Zeszyty Naukowe Akademii Morskiej w Szczecinie; 2019, 60 (132); 203-209
1733-8670
2392-0378
Pojawia się w:
Zeszyty Naukowe Akademii Morskiej w Szczecinie
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The usage of antibiotics for prevention of contamination in 3T3-L1 preadipocyte culture
Autorzy:
Ariyanto, Eko Fuji
Wikayani, Tenny Putri
Qomarilla, Nurul
Powiązania:
https://bibliotekanauki.pl/articles/1076667.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
3T3-L1 preadipocytes
antibiotics
contamination
Opis:
Background: 3T3-L1 preadipocyte is the most commonly used cell line in in vivo studies of obesity. One of the main concerns in 3T3-L1 preadipocyte culture is microorganism contaminations. The objective of this study was to determine the appropriate antibiotics to prevent contaminations in 3T3-L1 cultures. Method: This study used descriptive analysis. Frozen 3T3-L1 preadipocytes were thawed and cultured in DMEM-10% FBS-1% penicillin-streptomycin, DMEM-10% FBS-1% penicillin-streptomycin-fungiezone, or DMEM-10% FBS-0.2% ciprofloxacin 200 mg/100 ml. After 24-hour incubation, the cells were observed under the microscope for any change in the medium colour, presence of abnormal structures, and abnormality in cell morphology. Results: The usage of 1% penicillin-streptomycin, 1% penicillin-streptomycin-fungiezone, or 0.2% ciprofloxacin 200 mg/100 ml maintained the clean medium and conserved normal fibroblast-like morphology of the cells. Conclusion: This study suggested that 1% penicillin-streptomycin, 1% penicillin-streptomycin-fungiezone, or 0.2% ciprofloxacin 200 mg/100 ml can be utilized in 3T3-L1 preadipocyte cultures to prevent contaminations.
Źródło:
World News of Natural Sciences; 2019, 26; 218-223
2543-5426
Pojawia się w:
World News of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Susceptibility to antibiotics of bacterial microorganisms most commonly isolated from clinical and subclinical forms of mastitis in cows
Autorzy:
Radzikowski, Daniel
Powiązania:
https://bibliotekanauki.pl/articles/1178235.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
antibiotic therapy
antibiotics
dairy cows
mastitis
resistance
sensitivity
Opis:
Mastitis is an increasing problem in dairy farms and in the dairy industry. The paper presents changes in susceptibility of strains of bacteria isolated from quarter milk cows from mastitis in 2011, 2012, 2013, 2014, 2015 in the Factory Laboratory of Dairy Cooperative in south-eastern Poland. In total, 3409 strains of staphylococci, 2774 strains of streptococci and 423 strains of E. coli were isolated in these years. Susceptibility to antibiotics was examined by the disc diffusion method on Mueller-Hinton base. On the basis of the research it can be concluded that the highest sensitivity of staphylococci in all study periods is found for cefguin (from 91.2% to 96.1%) and cefapirin (92.2% to 96.2%), and the smallest for tetracycline (18 %), streptomycin (11.9%) and amoxicillin (9.3%). The highest sensitivity of bacteria from the Streptococcus family are cefapirin (97%), cefquinome (96.1%), amoxycycline (95.6%) and cefalexin (89.9%) on average in all years of research. The highest resistance was found for neomycin and streptomycin. They show that during the period under study over 90% of Escherichia coli were sensitive to streptomycin. Sensitivity at the level of 70%-80% was noted for amoxicillin, neomycin and cefapirin. The highest resistance of E. coli bacilli evolved for cefallaxin and tetracycline. Accordingly, early diagnosis of a pathogenic pathogen, and then selecting the appropriate form of treatment, gives you the opportunity to minimize the loss of mastitis in dairy cows.
Źródło:
World Scientific News; 2018, 93; 107-114
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sensitivity to antimicrobials of faecal Buttiauxella spp. from roe and red deer (Capreolus capreolus, Cervus elaphus) detected with MALDI-TOF mass spectrometry
Autorzy:
Lauková, A.
Pogány Simonová, M.
Kubašová, I.
Miltko, R.
Bełżecki, G.
Strompfová, V.
Powiązania:
https://bibliotekanauki.pl/articles/2087696.pdf
Data publikacji:
2018
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Buttiauxella
roe deer
red deer
antibiotics
sensitivity
enterocins
Źródło:
Polish Journal of Veterinary Sciences; 2018, 21, 3; 543-547
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Opportunities and threats in the post-antibiotic era
Szanse i zagrożenia u schyłku ery antybiotykowej
Autorzy:
Weiner, M.
Powiązania:
https://bibliotekanauki.pl/articles/2052867.pdf
Data publikacji:
2018
Wydawca:
Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej
Tematy:
bacteria
resistance
antibiotics
globalisation
globalizacja
bakterie
oporność
antybiotyki
Opis:
The following article reviews the issue of antibiotic resistance of microorganisms to meropenem in intensive care units in Ukraine. An increase in meropenem inefficiency against microorganisms in intensive care units has been observed in the last years. The data analysis suggests a significant predominance of gram-negative flora: A. baumannii, Р. aeruginosa, Antimicrobial resistance happens when microorganisms change when they are exposed to antibiotics. Then, treatment becomes ineffective and infections persist in the body, increasing the risk of spreading to other persons. The new resistance mechanisms that are emerging and spreading globally cause that the so far applied methods of treatment do not work, threatening the human ability to resist common infectious diseases, which in turn results in prolonged infections or even death. Antimicrobial resistance occurs naturally over time, usually through genetic changes. However, the misuse and overuse of antimicrobials are accelerating this process. It has become common to overuse and misuse antibiotics both in people and animals, which are often prescribed without professional oversight. Antimicrobial resistance is a complex problem that affects all of society and is driven by many interconnected factors. Single, isolated interventions have limited impact. Coordinated action is required to minimise the emergence and spread of antimicrobial resistance.
Ze zjawiskiem antybiotykooporności mamy do czynienia w przypadku gdy bakteria nabierze oporności na dany antybiotyk. Stosowane wówczas leczenie staje się nieskuteczne a obecność samego drobnoustroju w ciele chorego może przyczynić się do jego rozpowszechnienia na inne osoby. Nowe mechanizmy nabywania oporności na antybiotyki sprawiają, że dotychczasowe sposoby leczenia wielu chorób zakaźnych przestają być skuteczne, czego następstwem są trwające znacznie dłużej zachorowania a nawet śmierć. Zjawisko nabywania oporności nie jest czymś nowym, gdyż wynika z naturalnych właściwości przystosowawczych bakterii jednakże niewłaściwe lub nadużywanie antybiotyków zarówno u ludzi jak i zwierząt znacznie przyspiesza ten proces. Problem antybiotykooporności stał się problemem ogólnoświatowym, dotyczącym wszystkich grup społecznych. Ze względu na złożoność problemu potrzebne są skoordynowane działania gdyż tylko takie mogą przyczynić się do zminimalizowania rozprzestrzeniania tego niekorzystnego zjawiska.
Źródło:
Health Problems of Civilization; 2018, 12, 2; 88-93
2353-6942
2354-0265
Pojawia się w:
Health Problems of Civilization
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Vaccinium myrtillus leaves and Frangula alnus bark derived extracts as potential antistaphylococcal agents
Autorzy:
Sadowska, Beata
Paszkiewicz, Małgorzata
Podsędek, Anna
Redzynia, Małgorzata
Różalska, Barbara
Powiązania:
https://bibliotekanauki.pl/articles/1039358.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
phytocompounds
antimicrobial activity
synergism with antibiotics
biocompatibility index
Opis:
Due to constantly increasing antibiotic resistance of pathogens and participation of the biofilms they make in various types of infections, a development of alternative therapeutic strategies becomes an urgent need. Taking advantage of the biological activity of plant-derived compounds can solve this problem. In this study antimicrobial, including those synergistic with classic antibiotics, and cytotoxic properties of newly-obtained extracts from Vaccinium myrtillus leaves (VLE) and Frangula alnus bark (FBE) were evaluated. Both tested extracts exhibited relevant antistaphylococcal activity (MIC range 0.75-1.5 mg/mL) accompanied by a relativly low cytotoxic effect on mammalian cells (BI > 1). Phytochemical analysis of the extracts tested showed a high total content of phenolic compounds with the predominance of hydroxycinnamic acids in VLE and hydroxybenzoic acids and flavanols in FBE. Widely described in the literature antimicrobial properties of phenolics were probably connected with the biological activity of the extracts tested. We also report that the presence of VLE or FBE at sub-MIC concentrations enhances biocidal potential of vancomycin and linezolid. Therefore, we are considering a possibility of an alternative therapy for local infections caused by S. aureus by combining classic antibiotics with plant-derived extracts.
Źródło:
Acta Biochimica Polonica; 2014, 61, 1; 163-169
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
In vitro pharmacological interaction of caffeine and first-line antibiotics is antagonistic against clinically important bacterial pathogens
Autorzy:
Olajuyigbe, Olufunmiso
Adeoye-Isijola, Morenike
Okon, Victoria
Adedayo, Otunola
Coopoosamy, Roger
Powiązania:
https://bibliotekanauki.pl/articles/1038643.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
antibacterial activity
bacterial isolates
caffeine
antibiotics
antagonistic effects
Opis:
The in vitro antibacterial activity of pure caffeine powder and its interaction with first line antibiotic against bacterial isolates were investigated with the macrobroth dilution and the checkerboard assay methods. This study showed that caffeine and the antibiotics exhibited various degrees of antibacterial activities. While caffeine had MICs ranging between 67.19 and 268.75 µg/ml, chloramphenicol was characterized by MICs between 0.98 and 31.25 µg/ml, kanamycin - 15.63-62.5 µg/ml, nalidixic acid - 0.49-250 µg/ml, erythromycin - 0.49-62.5 µg/ml, tetracycline - 1.99-62.5 µg/ml and metronidazole - 15.63-31.25 µg/ml. Combining ½ MICs and MICs of caffeine with the antibiotics as well as direct combination of caffeine and the antibiotics resulted in significant reduction of antibiotics' effectiveness. The fractional inhibitory concentration index (FICI) for the combination of ½ MICs of caffeine with different antibiotics showed antagonistic interactions with the antibiotics except kanamycin which had additive and indifferent interactions with caffeine. The FICI of the MICs of caffeine combined with antibiotics showed a reduction in the number of antagonistic interactions as chloramphenicol, nalidixic acid and erythromycin showed some indifferent interactions while kanamycin was the only antibiotic that showed indifferent interaction against all the bacterial isolates. The direct combination of caffeine and the antibiotics resulted in significant antagonistic interactions higher than in the case when caffeine, at the ½ MICs and MICs, was combined with the antibiotics. Although caffeine demonstrated significant antibacterial activity against the selected bacterial isolates, its combination with the selected antibiotics resulted in significant antagonistic interactions. Caffeine should not be combined with antibiotics as this could result in serious therapeutic failure and, possibly, drug toxicity in vivo.
Źródło:
Acta Biochimica Polonica; 2017, 64, 2; 255-263
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analysis of Acinetobacter baumannii resistance patterns in patients with chronic obstructive pulmonary disease (COPD) in terms of choice of effective empiric antibiotic therapy
Autorzy:
Grochowalska, Aneta
Kozioł-Montewka, Maria
Sobieszczańska, Anna
Powiązania:
https://bibliotekanauki.pl/articles/989765.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
copd
antibiotics
acinetobacter baumannii
multidrug-resistant strains
co-infection
Opis:
Introduction. Multi-resistant Acinetobacter baumannii isolated from patients has become one of the most hazardous pathogens in health care settings. The aim of the study was to analyze pneumonia caused by Acinetobacter baumannii in patients hospitalized because of exacerbation of chronic obstructive pulmonary diseases (COPD), who were admitted to the Pulmonology Ward of the Masovian Specialistic Hospital in Radom (MSS). The incidence and drug sensitivity of these non-fermenting rods were evaluated, and compliance with antimicrobial procedure with the algorithm of the guidelines in applicable recommendations, was estimated. This should result in determining the local patterns of resistance and verifying therapeutic procedures in accordance with the assumptions of hospital antibiotic policy. In addition, the study examined the effectiveness of empiric and targeted therapy according to the clinical condition of the patient, and the eradication of A. baumannii, in comparison with the aggravating factors of the patient. Materials and Method. The retrospective study included 90 patients with exacerbation of COPD whose etiological factor of infection was A. baumannii, hospitalized in the Department of Pulmonology (MSS) in 2012–2016. Results. Studies were conducted on 90 patients with COPD exacerbation from which A. baumannii was isolated. Co-infections with other bacterial species among 41 patients were additionally noted. The majority of A. baumannii strains showed a high resistance (90%) to fluoroquinolones, ceftazidime, piperacillin/tazobactam. For strains causing a co-infection, drug resistance was successively 44–56%, 44%, 44%. All of patients received empirical therapy. The most commonly used drug was amoxicillin with a clavulanic acid, often combined with fluoroquinolone. This type of therapy was effective among 10% of patients. The mortality in this group was determined at 29%. Among 79% of patients with COPD, a targeted therapy was performed which proved to be effective in 58% of treated cases by susceptibility testing. The highest efficacy was observer after the use of colistin and carbapenems. Conclusion. In the performed study, the infections caused by multi-resistant Acinetobacter baumannii, were observed in COPD, which should be taken into consideration in choosing empirical antibiotic therapy. Simultaneously, the local resistance patterns of multi-drug-resistant (MDR) Gram-negative strains co-infecting COPD should be considered in empirical treatment. Moreover, both additional clinical complication and co-infections contribute to a more severe course of diseases. In this study, the mortality percent exceeded 29%.
Źródło:
Annals of Agricultural and Environmental Medicine; 2017, 24, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Resistance to the tetracyclines and macrolidelincosamide-streptogramin group of antibiotics and its genetic linkage - a review
Autorzy:
Marosevic, Durdica
Kaevska, Marija
Jaglic, Zoran
Powiązania:
https://bibliotekanauki.pl/articles/989867.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
antibiotics
genetic determinants of resistance
transposons
transmission of resistance
Opis:
An excessive use of antimicrobial agents poses a risk for the selection of resistant bacteria. Of particular interest are antibiotics that have large consumption rates in both veterinary and human medicine, such as the tetracyclines and macrolidelincosamide-streptogramin (MLS) group of antibiotics. A high load of these agents increases the risk of transmission of resistant bacteria and/or resistance determinants to humans, leading to a subsequent therapeutic failure. An increasing incidence of bacteria resistant to both tetracyclines and MLS antibiotics has been recently observed. This review summarizes the current knowledge on different tetracycline and MLS resistance genes that can be linked together on transposable elements.
Źródło:
Annals of Agricultural and Environmental Medicine; 2017, 24, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Organic Micropollutants from an Agricultural Drainage Ditch Contaminate a Shrimp Farm in Sinaloa (Mexico)
Autorzy:
Moeder, Monika
Carranza-Diaz, Otoniel
López-Angulo, Gabriela
Ahumada-Santos, Yesmi Patricia
Schrader, Steffi
Reemtsma, Thorsten
Delgado-Vargas, Francisco
Powiązania:
https://bibliotekanauki.pl/articles/24201795.pdf
Data publikacji:
2023
Wydawca:
Polskie Towarzystwo Inżynierii Ekologicznej
Tematy:
pesticides
pharmaceutical residues
antibiotics
coliforms
aquaculture
agricultural draining ditch
Opis:
Among nutrients and pesticides, agricultural draining ditches also transport pollutants discharged with untreated wastewater from the municipalities adjoining the ditch. When the ditch water is used for irrigation and aquaculture, risks for the environment and food production are suggested. For the conducted field study, a shrimp farm in Sinaloa (Mexico) was used to trace organic pollutants (pesticides and pharmaceutical residues) on their way from an agricultural draining ditch to a shrimp farm fed partially by the drain water. The concentrations of pollutants in the drain water ranged from 10 ng L-1 to 453 ng L-1. The pond water of the shrimp farm contained concentrations between <10 ng L-1 and 177 ng L-1. The shrimps were contaminated by pollutants at concentrations between 40 μg kg-1 d.w. (dry weight) to 3.3 mg kg-1 d.w. (fungicide Metalaxyl). Health risks for the cultivated shrimps cannot be excluded because some pesticides are known for their toxic effects to crustaceans. The concentrations of selected antibiotics in the shrimps were low and comparable with those found in the shrimps declared as seawater shrimps from a German supermarket. The incorporation of the antibiotics was probably caused by contact to the wastewater in the shrimp ponds and/or by contaminated shrimp feed. Additionally to the anthropogenic chemicals, coliforms were determined in the water (total coliforms: 30-50 CFU 100 mL-1; fecal coliforms: 0-20 CFU 100 mL-1). These values agree with the Mexican Norm NOM-242-SSA1-2009 representing a microbiological quality of water adequate for aquaculture. The number of coliforms measured in shrimp was higher than in pond water, suggesting bioaccumulation and a potential health risk for consumers.
Źródło:
Journal of Ecological Engineering; 2023, 24, 3; 143--152
2299-8993
Pojawia się w:
Journal of Ecological Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-25 z 73

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