- Tytuł:
- Synthesis and biological activity of pyrazole and 1,2,3-triazole containing heterocyclic compounds
- Autorzy:
-
Bhola, Yogesh
Naliapara, Ashutosh
Modi, Jigna
Naliapara, Yogesh - Powiązania:
- https://bibliotekanauki.pl/articles/1076027.pdf
- Data publikacji:
- 2019
- Wydawca:
- Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
- Tematy:
-
XRD crystal
antibacterial
azides
hydrazones
pyrazol
triazole - Opis:
- As heterocyclic compounds show good biological activity, we have synthesized nitrogen containing compounds among them 9a, 9c, 9e and 9f have shown very good antimicrobial activity with remarkable inhibition zones. N'-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-5-methyl-1-phenyl-1H-1,2,3-triazole-4-carbohydrazide (9a-i, 10) was synthesized from 5-(aryloxy)-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde and 5-methyl-1-phenyl-1H-1,2,3-triazole-4-carbohydrazide by condensation in acidic media. 5-(aryloxy)-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde and 5-methyl-1-phenyl-1H-1,2,3-triazole-4-carbohydrazide were synthesized from phenyl hydrazine and substituted anilines respectively. All intermediates and final compounds were confirmed by 1H-NMR, 13C-NMR, Mass Spectroscopy methods and compound 9c was confirmed by single XRD analysis.
- Źródło:
-
World Scientific News; 2019, 117; 29-43
2392-2192 - Pojawia się w:
- World Scientific News
- Dostawca treści:
- Biblioteka Nauki