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Tytuł:
Tuberculosis of gall-bladder mimicking malignancy – a case report
Autorzy:
Dahiya, Divya
Kaman, Lileswar
Rajendran, Jayapal
Garg, Mandeep
Powiązania:
https://bibliotekanauki.pl/articles/1393918.pdf
Data publikacji:
2016
Wydawca:
Index Copernicus International
Tematy:
gall-bladder tuberculosis
gall-bladder cancer
hepatobiliary tuberculosis
tuberculosis
Opis:
A correct preoperative diagnosis of gall-bladder tuberculosis is exceptionally unusual in the absence of pathognomic features both on clinical presentation and on imaging. Herein we present a case of 50 year female who was operated with a provisional diagnosis of gall-bladder malignancy and was found to have tuberculosis of gall-bladder on histopathology
Źródło:
Polish Journal of Surgery; 2016, 88, 5; 504-509
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Incidence of tuberculosis in the Tatras region
Autorzy:
Gulášová, Ivica
Gornerová, Lenka
Breza jr., Ján
Breza, Ján
Powiązania:
https://bibliotekanauki.pl/articles/2157018.pdf
Data publikacji:
2014
Wydawca:
Instytut Studiów Międzynarodowych i Edukacji Humanum
Tematy:
pulmonary tuberculosis
extrapulmonary tuberculosis
epidemiological situation
region
vaccination
Opis:
The authors point out that tuberculosis is the oldest infectious killer of humans and today it is such a serious threat to health that the World Health Organization (WHO) equates it to a time bomb. The most common source of infection by mycobacteria tuberculosis to a man is a sick person. Epidemiologically greatest danger is sick person with untreated decay pulmonary tuberculosis whose sputum may spread billions of tuberculosis bacilli every day. The overall situation in the incidence of tuberculosis (TB) in Slovakia is generally favorable, although in the eastern parts of Slovakia incidence is growing rapidly. Slovakia has compared with all Europe small to moderate incidence of this disease and its incidence has downward trend. East Slovakia so far has hot won combat this disease yet. It is therefore necessary to continue effective intervention and prevention to combat the spread of this disease.
Źródło:
Społeczeństwo i Edukacja. Międzynarodowe Studia Humanistyczne; 2014, 2(14); 163-170
1898-0171
Pojawia się w:
Społeczeństwo i Edukacja. Międzynarodowe Studia Humanistyczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Surgical Management of Genitourinary Tuberculosis: our Experience and review of literature
Autorzy:
Mittal, Ankur
Ranjan, Satish
Narain, Tushar
Panwar, Vikas
Powiązania:
https://bibliotekanauki.pl/articles/1391814.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
antitubercular treatment (ATT)
extrapulmonary tuberculosis (EPTB)
genitourinary system (GUS)
genitourinary tuberculosis (GUTB)
tuberculosis (TB)
Opis:
Background: Genitourinary tuberculosis is one of the most common forms of extra-pulmonary tuberculosis. Owing to a myriad of clinical presentations and discrepancies in the diagnostic modalities, patients usually present late, which results in a high number of them requiring surgical intervention. The present study aims to retrospectively analyze the role of surgery in genitourinary tuberculosis. Patients and method: All patients diagnosed with genitourinary tuberculosis at our centre between October 2017 and September 2019 were included in the study. The mode of presentation, duration of symptoms, investigations performed, treatment received, and follow-up were studied. Results: Out of 25 patients diagnosed with genitourinary tuberculosis (GUTB), there were 15 (60%) males and 10 (40%) females. The mean age of presentation was 40.84 years. Nineteen (76%) patients underwent surgical intervention, and many patients required more than one surgical procedure. A reconstructive procedure was carried out in seven patients. At a median follow-up of 12 months, all patients did well, showing no relapse. Conclusion: Surgery, along with antitubercular treatment, is the key to the management of GUTB presenting with structural damage. However, surgery can be ablative or reconstructive, depending on various factors discussed in the present study. This preserves or restores the optimal function of the genitourinary system affected by the mycobacterium bacilli.
Źródło:
Polish Journal of Surgery; 2020, 92, 6; 1-6
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Extrapulmonary tuberculosis: An overview on infection beyond Lungs
Autorzy:
Khusro, Ameer
Aarti, Chirom
Powiązania:
https://bibliotekanauki.pl/articles/1031696.pdf
Data publikacji:
2020
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Clinical monitoring
Extrapulmonary tuberculosis
Organs
Tissues
Tuberculosis
Opis:
Extrapulmonary tuberculosis (EPTB) involves 10-15% of all tuberculosis (TB) cases. Recent statistical report showed that EPTB accounts for more than 50% of all cases of TB in HIV-positive patients. In spite of existing anti-tubercular drugs based treatment of EPTB, the ideal regimen and duration of treatment have not yet been established. In general, EPTB is a kind of TB infecting diversified tissues and organs of body other than lungs. In fact, people suffering from TB and co-infected with HIV are prone to develop EPTB much more frequently. The present chapter discusses on the general overviews of EPTB infecting distinct body sites other than lungs. Currently, the treatment of EPTB completely relies on existing anti-tubercular drugs. In addition, significant efforts, particularly close clinical monitoring would be an imperative step towards its therapeutic strategy.
Źródło:
World News of Natural Sciences; 2020, 28; 131-141
2543-5426
Pojawia się w:
World News of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Standards of Tuberculosis care: An Indian perspective
Autorzy:
Shrivastava, SR.
Shrivastava, PS.
Ramasamy, J.
Powiązania:
https://bibliotekanauki.pl/articles/1914051.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
Tuberculosis
International standards for Tuberculosis care
India
Opis:
Tuberculosis (TB) is a social disease with medical aspects accounting for 8.7 million new cases and 1.4 million deaths in the year 2011 worldwide. International standards for TB care (ISTC) were formulated to develop uniform guidelines for ensuring the delivery of a widely accepted level of care by all health care practitioners in managing TB patients, or those suspected to have tuberculosis. India alone has contributed 25% of the globally reported new cases of TB in 2011 and is also the leading nation in accounting for drug resistant TB (DR-TB). Thus to develop uniform standards of TB care and to engage private sector which caters to more than 70% of TB patients, the “central TB division” has developed standards of TB care in India (STCI). These local standards have been designed after taking into account the guidelines of the World Health Organization and ISTC disease control STCI has proposed 26 standards (viz. diagnosis – 1 to 6; treatment – 7 to 11; public health – 12 to 21; social inclusion – 22 to 26) for effective prevention and control of TB. To conclude, the Indian standards of TB care have been proposed to emphasize on individual patient care and public health principles of disease control for ultimately reducing not only the suffering but also the economic losses from tuberculosis.
Źródło:
Progress in Health Sciences; 2014, 4, 1; 280-282
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The role of BCG in prevention of tuberculosis and the strategies to improve its immunogenicity
Rola BCG w zapobieganiu gruźlicy i strategie prowadzące do zwiększenia jej immunogenności
Autorzy:
Mazurek, Jolanta
Powiązania:
https://bibliotekanauki.pl/articles/2097704.pdf
Data publikacji:
2018-06-22
Wydawca:
Państwowa Wyższa Szkoła Zawodowa w Tarnowie
Tematy:
gruźlica
szczepionka
BCG
Mycobacterium tuberculosis
tuberculosis
vaccine
Opis:
Tuberculosis (TB) remains a major public health problem and the main cause of death from the infectious diseases worldwide. Mycobacterium tuberculosis (Mtb), a causative agent of tuberculosis, is the oldest known human pathogen. The only available TB vaccine, BCG, was first administered in 1921 and since then remains the only protecting tool against TB. Yet, its efficacy is limited and there is an urgent need to design and produce a novel vaccine that will protect against this deadly disease in the era of emerging problems with antibiotic resistance. In this review a current, global TB situation is outlined and the characteristics of BCG are presented. Finally, the strategies leading to generation of BCG variants providing improved protecting efficacy are shortly described.
Gruźlica pozostaje ważnym problemem zdrowia publicznego i jest główną przyczyną zgonów z powodu chorób zakaźnych na całym świecie. Mycobacterium tuberculosis (Mtb), bakteria wywołująca gruźlicę, jest najstarszym znanym ludzkim patogenem. Jedyną dostępną szczepionkę przeciwgruźliczą, BCG, po raz pierwszy zastosowano już w 1921 r. i od tego czasu pozostaje ona jedynym narzędziem zapobiegającym gruźlicy. Jej skuteczność jest jednak ograniczona i istnieje pilna potrzeba zaprojektowania i wyprodukowania nowej szczepionki, która chroni przed tą śmiercionośną chorobą, szczególnie w dobie pojawiających się problemów z antybiotykoopornością Mtb. W niniejszej pracy przeglądowej opisano aktualną, globalną sytuację epidemiologiczną dotyczącą gruźlicy i przedstawiono charakterystykę BCG. Opisano także strategie prowadzące do wytworzenia wariantów BCG zapewniających lepszą ochronę przeciwgruźliczą.
Źródło:
Health Promotion & Physical Activity; 2018, 2, 1; 17-22
2544-9117
Pojawia się w:
Health Promotion & Physical Activity
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Gruźlica – od diagnostyki do leczenia według standardów dla krajów Unii Europejskiej
Tuberculosis – from diagnosing to treatment according to the European Union standards
Autorzy:
Grzelewska-Rzymowska, Iwona
Mańkowska-Baczyńska, Katarzyna
Górski, Paweł
Powiązania:
https://bibliotekanauki.pl/articles/1032967.pdf
Data publikacji:
2013
Wydawca:
Medical Communications
Tematy:
IGRA tests
Mycobacterium tuberculosis
antituberculosis drugs
latent tuberculosis
tuberculosis
gruźlica
mycobacterium tuberculosis
leki przeciwprątkowe
gruźlica utajona
testy igra
Opis:
In the article the authors presented the epidemiological data referring to tuberculosis in some countries and in Poland. Tuberculosis continues to be a priority challenge for public health. The present chemotherapy for tuberculosis is very efficacious but has the disadvantages of being lengthy and complex. The serious problems remain drug-resistant strains of Mycobacterium tuberculosis, especially multi-drug MDR-TB and extensively-drug resistant XRD-TB as well as the prevalence of HIV co-infection among tuberculosis cases. In October, 2011 the European Union Standards for Tuberculosis Care (ESTC) were finalized. This document is consistent with WHO definitions and recommendations. ESTC consists of four sections – diagnosis, treatment, HIV and comorbidities and public health, which correspond to the International Standards for Tuberculosis Care (ISTC) from 2009. In 2013, the Polish recommendations for tuberculosis were published. The authors of this paper comment on all recommendations referring to tuberculosis. Clinical symptoms of tuberculosis and some problems connected with latent tuberculosis are presented. All sputum specimens and other samples should be submitted for microscopic, culture and drug susceptibility tests. WHO recommends rapid molecular assay, which should be performed on the day of microbiological diagnosis of tuberculosis. All patients, including those with HIV infection, who have not been previously treated and without any risk factors for drug resistance, should receive isoniazid, rifampicin, pyrazinamide and ethambutol for two months and isoniazid and rifampicin for four months. Some standards are devoted to children tuberculosis. Infection evoked by Mycobacterium tuberculosis should be elicited using tuberculin skin test and/or interferon gamma release assay (IGRA test). Children under 5 years of age and patients with HIV infection should be treated for latent tuberculosis infection with isoniazid when they do not have active tuberculosis.
Autorzy przedstawiają dane epidemiologiczne odnoszące się do gruźlicy w niektórych krajach, w tym w Polsce. Gruźlica ciągle pozostaje priorytetowym wyzwaniem dla zdrowia publicznego. Obecnie stosowana chemioterapia jest skuteczna, ale długotrwała i kompleksowa. Poważny problem stanowią szczepy Mycobacterium tuberculosis oporne na leki przeciwprątkowe, szczególnie szczepy oporne na wiele leków (MDR-TB) i te o rozszerzonej oporności (XDR-TB), oraz zakażenia HIV wśród chorych na gruźlicę. W październiku 2011 roku zostały sfinalizowane standardy dotyczące gruźlicy dla krajów Unii Europejskiej (European Union Standards for Tuberculosis Care, ESTC). Dokument ten pozostaje w zgodzie z definicjami i rekomendacjami WHO. ESTC składają się z czterech sekcji: diagnozowanie, leczenie, HIV i choroby współistniejące, zdrowie publiczne, które korespondują z Międzynarodowymi Standardami Opieki nad Chorymi na Gruźlicę (ISTC) z 2009 roku. W 2013 roku zostały opublikowane polskie rekomendacje. Autorzy komentują wszystkie odnoszące się do gruźlicy rekomendacje. Przedstawiono objawy kliniczne gruźlicy i wybrane problemy gruźlicy utajonej (latent tuberculosis). Próbki wydzieliny oskrzelowej powinny być poddane badaniu mikroskopowemu, hodowli i testom lekowraźliwości. WHO rekomenduje szybki test molekularny, który należy wykonać w dniu bakteriologicznej diagnozy gruźlicy. Wszyscy chorzy (w tym osoby zakażone HIV), którzy nie byli wcześniej leczeni i u których nie występują czynniki ryzyka oporności na leki, powinni otrzymywać przez 2 miesiące izoniazyd, ryfampicynę, pirazynamid i etambutol, a przez 4 miesiące izoniazyd i ryfampicynę. Niektóre standardy odnoszą się do gruźlicy dziecięcej. Infekcja wywołana przez Mycobacterium tuberculosis powinna zostać wykryta za pomocą testu tuberkulinowego lub testu uwalniania interferonu gamma (IGRA). Dzieci poniżej 5. roku życia i osoby zakażone HIV, u których stwierdzono gruźlicę utajoną, należy leczyć izoniazydem, jeśli nie stwierdza się u nich aktywnej gruźlicy.
Źródło:
Pediatria i Medycyna Rodzinna; 2013, 9, 3; 224-231
1734-1531
2451-0742
Pojawia się w:
Pediatria i Medycyna Rodzinna
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Treatment for active tuberculosis in giraffe (Giraffa camelopardalis) in a Zoo and potential consequences for public health - case report
Autorzy:
Krajewska-Wędzina, M.
Augustynowicz-Kopeć, E.
Weiner, M.
Szulowski, K.
Powiązania:
https://bibliotekanauki.pl/articles/2081930.pdf
Data publikacji:
2018
Wydawca:
Instytut Medycyny Wsi
Tematy:
tuberculosis
epidemiology
anti-tuberculosis therapy
public health
giraffe
Opis:
Introduction. Bovine tuberculosis (bTB) is an infectious disease that occurs in many species of both domestic and freeranging animals, as well as animals kept in zoos. According to the Polish regulations, cattle tuberculosis are slaughtered and microbiological examinations are performed, the rest of animal species can be treated and laboratory diagnostics are not obligatory. Case report. The presented case concerns two male giraffes which were purchased by the zoo and united with a third male. After a year, the oldest male died. Post mortem examinations confirmed generalized tuberculosis. After a further six months, the second male was euthanized after suffering great pain. The material for the study of drug resistance was a swab from the nose, obtained ante mortem from the third male. Attempted treatments did not produce the expected results. Genotyping allowed the exclusion of a common source of transmission. Conclusions. The final effect of the anti-tuberculosis therapy in the male giraffe raises the question whether the research team should have undertaken the treatment of the animal with active tuberculosis.
Źródło:
Annals of Agricultural and Environmental Medicine; 2018, 25, 4; 593-595
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Multi Drug Resistant Tuberculosis
Autorzy:
Zacharia, Balaji
Roy, Antony
Powiązania:
https://bibliotekanauki.pl/articles/454987.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
BACTEC
MDRTB
multi drug resistant tuberculosis Mycobacterium
tuberculosis
Opis:
Introduction. Tuberculosis is one of the oldest infections known to mankind. Of all infectious diseases, tuberculosis causes the most fatalities of any infection. The incidence of tuberculosis on the rise due to the increased prevalence of HIV infection. The incidence of drug resistance strains of mycobacterium is also on the rise. When the mycobacterium is resistant to both INH and rifampicin it is called multi drug resistant tuberculosis. There is a primary and an acquired type of drug resistance. Multidrug resistant tuberculosis is a not only a problem for the patient but also for society at large. The treatment of multidrug resistant tuberculosis requires an entirely different approach. Aim. In this review, we are going to describe the etiopathogenesis, diagnosis, investigations and treatment of multi drug resistant tuberculosis. Material and methods. Analysis of the current literature. Results. Genetic factors, previous treatment, and other factors predisposes the onset of drug resistance. By early detection and prevention of spread of drug resistant strains we can prevent the spread of resistant strains. Conclusion. Drug resistance in tuberculosis is a very complex and dangerous problem. We have to prevent the development and spread of MDRTB. Good quality drugs should be used and made available to all sections of the population. Enhancing the National tuberculosis programs is the best way to attain an effective way to control this menace.
Źródło:
European Journal of Clinical and Experimental Medicine; 2019, 3; 262-269
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Strengthening infrastructure in management of drug resistant tuberculosis in India
Autorzy:
Shrivastava, SR.
Shrivastava, PS.
Ramasamy, J.
Powiązania:
https://bibliotekanauki.pl/articles/1914046.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
tuberculosis
Revised National Tuberculosis Control Program
multi-drug resistant
India
Opis:
The emergence of resistance to first-line drugs used to treat tuberculosis (TB) has become a significant public health concern and an obstacle in implementation of effective TB control activities globally. In India, Revised National TB Control Program (RNTCP) introduced the programmatic management of drug-resistant TB (PMDT) services to address the needs of MDR-TB patients. To execute the plan with perfection, RNTCP has devised MDR suspect criteria – A, B, and C so that gradually PMDT services can be extended to the whole country. These criteria were framed to run in tandem with the strengthening of the laboratory services so that the existing certified laboratories can carry out the culture and DST services without being overburdened. Altogether, RNTCP is committed for the strengthening and capacity building of its resources to offer culture and DST services right at the time of diagnosis.
Źródło:
Progress in Health Sciences; 2014, 4, 1; 277-279
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antimycobacterial activity of ethanolic extract of Artemisia absinthium L.
Autorzy:
Hojageldiyev, T.
Bolmammedov, Y.
Gurbanaliyev, S.
Powiązania:
https://bibliotekanauki.pl/articles/1075710.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Artemisia absinthium
Mycobacteria tuberculosis
Mycobacterium tuberculosis
antimycobacterial
ethanolic extract
Opis:
It is known that, drugs used in the treatment of tuberculosis show toxic effect to organism especially to liver beside its therapeutic effect. Because of ineffectiveness of drugs used in the treatment regimen of tuberculosis against multidrug resistance (MDR) and extensively drug-resistance (XDR) tuberculosis requires the development of new treatment methods and new novel drugs. Considering the usage of Artemisia absinthium in traditional medicine in treatment of wounds which suggests its antibacterial activity it seems that, also it may have significant antimycobacterial activity. The objective of present study was to evaluate antibacterial activity of ethanolic extract of A. absinthium against M. tuberculosis. In this study, the effect of ethanolic extract of A. absinthium was tested against tuberculosis and pharmaco-toxicological properties evaluated on laboratory animals. The 20%, 40%, 70% and 96% ethanolic extracts of A. absinthium prepared then its bacteriostatic and bactericidal activities were evaluated by validated methods. Data were analyzed by GraphPad Prism 7.0 at the level P<0.05. Results showed that ethanolic extracts of A. absinthium show no toxicological properties with having high LD50. All concentrations of extract show high bacteriostatic activity on M. tuberculosis. 96% ethanolic extract has highest bactericidal effect among other concentrations. By conducting further studies, as a results of our study, antimycobacterial drug can be prepared from A. absinthium.
Źródło:
World Scientific News; 2019, 119; 224-230
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A comprehensive review on Primary gallbladder tuberculosis
Autorzy:
Gupta, Ashish
Gupta, Amit
Anjum, Rohik
Agrawal, Saumya
Mallik, Dhiraj
Powiązania:
https://bibliotekanauki.pl/articles/1392736.pdf
Data publikacji:
2018
Wydawca:
Index Copernicus International
Tematy:
gallbladder
Tuberculosis
Antitubercular drugs
Opis:
Tuberculosis (TB) is an infectious disease that can affect any organ system of the body. Abdominal TB can be gastrointestinal, lymph nodal, visceral or peritoneal. The gallbladder (GB) is rarely involved in abdominal TB as a primary organ. Extensive research literature on gallbladder TB is limited to case reports. There has been no review on this rare abdominal pathology. GB tuberculosis is a difficult diagnosis preoperatively. It is a rare differential among the more common gallbladder pathologies such as cholelithiasis, or a gallbladder malignancy. Typical histopathology of the resected specimen helps to establish this rare diagnosis. Subjecting every specimen to histopathological examination followed by medical treatment offers the chance of cure. Through this review, the authors attempt to provide an insight into this disease entity.
Źródło:
Polish Journal of Surgery; 2018, 90, 2; 10-12
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Utajone zakażenie gruźlicą u polskich funkcjonariuszy służby więziennej
Latent tuberculosis infection in the Polish prison staff
Autorzy:
Filipek-Czerska, Aneta
Karczewski, Jan K.
Gładysz, Iwona
Powiązania:
https://bibliotekanauki.pl/articles/2081865.pdf
Data publikacji:
2021-08-31
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
gruźlica
zakłady karne
latentne zakażenie prątkami gruźlicy
zakażenie Mycobacterium tuberculosis
infekcja utajona
służba więzienna
tuberculosis
penitentiaries
latent tuberculosis infection
Mycobacterium tuberculosis infection
latent infection
prison employees
Opis:
Gruźlica jest chorobą zakaźną wywoływaną przez prątki kwasooporne z grupy Mycobacterium tuberculosis complex. Choroba rozprzestrzenia się, gdy chorzy na gruźlicę płucną wydalają bakterie podczas kaszlu, kichania, śmiania się czy mówienia. Więzienia, które są często nazywane rezerwuarami chorych na gruźlicę, stwarzają duże zagrożenie dla zatrudnionych w nich osób. Dłuższy czas pracy w więzieniu i ośrodkach penitencjarnych sprzyja zakażeniu latentnemu wśród personelu więziennego. Dotychczas opublikowano niewiele prac dotyczących zagadnienia latentnego zakażenia prątkami gruźlicy wśród pracowników zakładów karnych.Materiał i metodyPrzebadano łącznie 84 pracowników zakładów karnych zlokalizowanych w województwie lubelskim. Zastosowano test QuantiFERON-TB Gold In-Tube (QFT-GIT), który w 2005 r. został zatwierdzony do użytku przez amerykańską Agencję ds. Żywności i Leków jako pomoc w diagnozowaniu zakażenia M. tuberculosis. Materiał do badań stanowiły próbki krwi pobrane metodą testu QFT-GIT.WynikiLatentne zakażenie gruźlicą stwierdzono u 16,6% funkcjonariuszy. Największy odsetek wyników dodatnich zaobserwowano wśród badanych funkcjonariuszek z zakładu karnego, w wieku 36–57 lat, stanu cywilnego wolnego. Nie wykazano istotnych statystycznie różnic między stanowiskiem pracy funkcjonariuszy służby więziennej a czynnikami ryzyka zakażenia gruźlicą latentną. Okazało się, że na ryzyko zakażenia gruźlicą wpływają staż pracy i kontakt z osadzonymi.Wnioski Wyniki badań częściowo potwierdzają obserwacje innych autorów dotyczące oddziaływania czynników ryzyka latentnego zakażenia gruźlicą pracowników zakładów karnych. W badanych zakładach karnych staż i kontakt miały wpływ na zakażenie. Med. Pr. 2021;72(4):415–422
Tuberculosis is a chronic infectious disease caused by acid-fast mycobacteria from the Mycobacterium tuberculosis complex group. The disease spreads when people with pulmonary tuberculosis excrete bacteria when they cough, sneeze, laugh or speak. Prisons are often called reservoirs of patients with tuberculosis, posing a great threat to their staff. Longer working hours in prison and penitentiary facilities aid latent contamination among the prison staff. So far, there have been few works discussing latent tuberculosis infection issues among the prisoners and prison staff.Material and MethodsA total of 84 employees of penitentiary facilities located in the Lublin Voivodship were examined using the QuantiFERON-TB Gold In-Tube (QFT-GIT) test which was approved for use in 2005 by the U.S. Food and Drug Administration as an aid in the diagnosis of Mycobacterium tuberculosis. The material for the research included blood samples collected using the QFT-GIT.ResultsPositive test results of latent tuberculosis infections were found in 16.6% of officers. The highest percentage with positive results of tuberculosis infections was found among the surveyed single women aged 36–57, working in penitentiary facilities. There have been no statistically significant differences between the position of officers and the risk factors increasing the chance of the latent tuberculosis infection. Work experience and contact with inmates were found to have an impact on tuberculosis infection.ConclusionsThe obtained results partially confirm other authors’ observations concerning the influence of the risk factors of latent tuberculosis infections in prisons. Work experience and contact with inmates have an impact on tuberculosis infections among the prison staff in the Lublin Voivodeship. Med Pr. 2021;72(4):415–22
Źródło:
Medycyna Pracy; 2021, 72, 4; 415-422
0465-5893
2353-1339
Pojawia się w:
Medycyna Pracy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cervical lymphadenitis as a result of (Hijab) pin prick in north of Jordan
Autorzy:
Gharaibeh, Mahmoud M.
Al Wadiya, Ahmed
Gharaibeh, Ahmad
Powiązania:
https://bibliotekanauki.pl/articles/2040135.pdf
Data publikacji:
2020-12-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
Hijab
lymphadenitis
tuberculosis
Opis:
Introduction. Cervical lymph nodes are lymph nodes found in the neck. Hijab is a head cover worn by some Muslim women in the presence of any adult male outside of their immediate family, which usually covers the head, neck and chest. It is strictly forbidden to Muslim woman to unveil any single hair of her head, so they use many pins around the head to fix their Hijab. Often, while using pins they are self-pricked. Aim. The main aim of our work is to reveal a new cause of lymphadenopathy, which is not known till now. Material and methods. Retrospective study during the past five years among seventy-five female outpatients, visited our Oral and Maxillofacial clinic in dental department. Our data was collected according to medical history of patients; all female patients with cervical lymphadenopathy were using (A hijab). Results. Data collected of 75 female patients. Lymphadenopathy causes were various. Most of these causes resulted from nonspecific lymphadenitis (67 patients), 4 tuberculosis, 2 lymphoma, 2 cat scratch disease. Aetiology of 67 nonspecific lymphadenitis was 40 patients of dental cause, 10 of sore throat, 7 of acne vulgaris, 3 of mild facial injuries, and 7 of (Hijab pin pricks). Conclusion. Hijab pin prick cervical lymphadenitis in Islamic communities is not uncommon and, unexplained cervical lymphadenitis should be considered as potential cause
Źródło:
European Journal of Clinical and Experimental Medicine; 2020, 4; 286-288
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A rare case of isolated pancreatic tuberculosis in a 70-year-old patient - a case report
Autorzy:
Słupski, Maciej
Wiciński, Michał
Khuat, Dawid
Pawlak-Osińska, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/1392244.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
pancreas
tuberculosis
tumor
Opis:
We report a case of rare solitary pancreatic tuberculoma. 70 years old woman admitted to hospital in order to conduct diagnostics of a tumor located in the head of the pancreas. All symptoms pointed at pancreatic cancer, but histopathological examinations were inconclusive. Additionally, there were no clinical signs or symptoms of tuberculosis in the lungs. X-ray of the chest showed no abnormalities. The patient denied tuberculosis in the medical interview. There were no bacilli in the sputum. During exploratory laparotomy, the samples of tissue have been taken for pathomorphological examination. The microscopic image caused suspicion of Mycobacterium tuberculosis etiology, which was confirmed by Ziehl-Neelsen staining. In recent years, tuberculosis has become more and more common in Europe, which is why the described case can be a guide for doctors to help to avoid diagnostic errors and speed up the treatment process.
Źródło:
Polish Journal of Surgery; 2019, 91, 2; 48-50
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analysis of resistance to antimycobacterial drugs among MTBC strains isolated from cattle in Poland as a threat to human health
Analiza oporności na leki przeciwprątkowe wśród szczepów MTBC izolowanych od bydła w Polsce jako zagrożenie dla zdrowia ludzi
Autorzy:
Weiner, M.
Krajewska, M.
Zabost, A.
Augustynowicz-Kopeć, E.
Szulowski, K.
Powiązania:
https://bibliotekanauki.pl/articles/2048912.pdf
Data publikacji:
2020
Wydawca:
Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej
Tematy:
drug resistance
Mycobacterium tuberculosis
bovine tuberculosis
public health
antimicrobial
lekooporność
Mycobacterium tuberculosis complex
gruźlica bydlęca
zdrowie publiczne
leki przeciwprątkowe
Opis:
Background. Tuberculosis is a highly contagious disease affecting humans and animals. It is caused by mycobacteria that are part of the Mycobacterium tuberculosis complex (MTBC). The etiological agent causing bovine tuberculosis is mycobacteria bovis: Mycobacterium bovis and Mycobacterium caprae. According to the World Health Organization bovine tuberculosis is classified as direct zoonosis. Material and methods. The study material consisted of 129 MTBC strains isolated from Polish cattle, which were microbiologically analyzed. The resistance phenotype was tested for first-line anti-tuberculosis drugs used in the treatment of tuberculosis in humans. The drugs included streptomycin, isoniazid, rifampicin, ethambutol, and pyrazinamide. The MTBC strains tested in this study were isolated from cattle tissue post mortem so that the determination of drug resistance could meet only the epidemiological criterion. Results. Polish strains of mycobacteria bovis have not acquired environmental resistance despite the huge dynamics of changes in the phenotype of mycobacterial tuberculosis resistance. Strains classified as M. bovis are characterized by natural resistance to PZA, which is typical of this species. Conclusions. Drug resistance imposes the use of additional drugs. Drugs that are less effective than the basic drugs, drugs causing side effects more frequently and drugs that are much more expensive.
Wprowadzenie. Gruźlica jest wysoce zakaźną chorobą ludzi i zwierząt, którą powodują prątki wchodzące w skład kompleksu Mycobacterium tuberculosis (MTBC). Czynnikiem etiologicznym gruźlicy bydlęcej są prątki bydlęce: Mycobacterium bovis i Mycobacterium caprae. Zgodnie z klasyfikacją Światowej Organizacji Zdrowia, gruźlica typu bydlęcego zaliczana jest do zoonoz bezpośrednich. Materiał i metody. W pracy poddano analizie mikrobiologicznej 129 szczepów MTBC wyizolowanych od bydła w Polsce. Fenotyp oporności zbadano pod kątem leków przeciwprątkowych pierwszej linii stosowanych w leczeniu gruźlicy u ludzi: streptomycyny, izoniazydu, rifampicyny, etambutolu i pyrazynamidu. Szczepy MTBC badane w niniejszej pracy wyizolowano z tkanek bydła pobranych post mortem, tak że oznaczenie lekooporności w tym zadaniu spełniło jedynie kryterium epidemiologiczne. Wyniki. Polskie szczepy prątka bydlęcego nie nabyły oporności środowiskowej. Szczepy sklasyfikowane jako M. bovis cechują się charakterystyczną dla tego gatunku naturalną opornością na PZA. Wnioski. Wystąpienie lekooporności zmusza do stosowania leków dodatkowych, mniej skutecznych niż leki podstawowe i powodujących częściej objawy uboczne, a jednocześnie znacznie droższych.
Źródło:
Health Problems of Civilization; 2020, 14, 1; 24-28
2353-6942
2354-0265
Pojawia się w:
Health Problems of Civilization
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Human as a potential vector of bovine tuberculosis in cattle
Autorzy:
Krajewska-Wedzina, M.
Weiner, M.
Anusz, K.
Augustynowicz-Kopeć, E.
Lipiec, M.
Szulowski, K.
Powiązania:
https://bibliotekanauki.pl/articles/2085020.pdf
Data publikacji:
2019
Wydawca:
Instytut Medycyny Wsi
Tematy:
bovine tuberculosis
Mycobacterium bovis
epidemiology
zoonosis
mycobacteriology
public health
transmission
tuberculosis
Opis:
Introduction and objective. Bovine tuberculosis (bTB, bovine TB) is caused by mycobacteria which are grouped within the MTBC. TB in animals is a highly infectious and progressive disease which can be transmitted to humans. Since 2009, Poland has gained official bTB-free status. Despite the official fact of bTB-free status, a dozen bTB outbreaks are still noted each year. Since 2000 in Poland, every year 1/5 of the national herd is subject to intradermal skin TB testing to control the bTB outbreaks in the cattle population. Application, with 5-year intervals between each government-funded skin test, undoubtedly resulted in financial savings. However it also seems to have caused several adverse and worrying events, e.g. an increase in the number of reactors detected and removed from a single tested herd. The objective of this study was the examination of 898 cattle imputed with bTB infection in Poland between 2008–2012. Materials and method. The study concerned a potential epidemic outbreak with suspected bTB transmission. 20 cows came from 3 herds in the same county located in the same province in southern Poland. Results. 134 MTBC strains were identified. In MIRU-VNTR, all isolates showed the same genetic pattern 322532243421232. Based on molecular investigation, the characteristics of M. bovis strains isolated from cattle from 3 different herds confirmed the common source of this zoonotic disease. Conclusions. Although not bacteriologically proven, everything points to the fact that humans were the vector of bovine tuberculosis transmission between herds. This finding confirms transmission between 3 cattle herds in the Małopolskie Province in southern Poland (Podhale). The outbreak of tuberculosis in animals finally compromised public health.
Źródło:
Annals of Agricultural and Environmental Medicine; 2019, 26, 3; 396-399
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A novel method of Mycobacterium tuberculosis complex strain differentiation using polymorphic GC-rich gene sequences
Autorzy:
Kotłowski, Roman
Powiązania:
https://bibliotekanauki.pl/articles/1039112.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Mycobacterium tuberculosis complex
PGRS
genotyping
Opis:
Tuberculosis is one of the leading infectious diseases. In this work, a new genotyping method of Mycobacterium tuberculosis (Mtb) complex strain is presented. 27 Mtb genomes were analyzed for the presence of length polymorphism within polymorphic GC-rich gene sequences. Four genes, Rv3345c, Rv3507, Rv0747 and Rv3511, showing variation in length depending on the Mtb strain were selected for designing primer sequences flanking variable regions for the PCR method. Identification of 16 genotypes among 27 analyzed genomes demonstrated usefulness of our genotyping method in differentiation of Mtb genomes based on sequence polymorphism in the four PGRS genes.
Źródło:
Acta Biochimica Polonica; 2015, 62, 2; 317-322
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Lymphoma co existing with Tuberculosis granulomatous
Autorzy:
Subhan, Madeeha
Sadiq, Waleed
Powiązania:
https://bibliotekanauki.pl/articles/1178816.pdf
Data publikacji:
2017
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Hodgkin
Tuberculosis granulomatous
cervical
lymphoma
Opis:
Hodgkin lymphoma is malignant condition with good prognosis. Asymptomatic lymphadenopathy is a manifestation with cervical, supraclavicular and mediastinal lymph nodes.
Źródło:
World Scientific News; 2017, 90; 265-270
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A comprehensive review of primary gall bladder tuberculosis
Autorzy:
Gupta, Ashish
Gupta, Amit
Anjum, Rohik
Agrawal, Saumya
Mallik, Dhiraj
Powiązania:
https://bibliotekanauki.pl/articles/1392422.pdf
Data publikacji:
2018
Wydawca:
Index Copernicus International
Tematy:
Gall bladder
Tuberculosis
Antitubercular drugs
Opis:
Tuberculosis (TB) is an infectious disease that can involve any organ system of the body. Abdominal TB can be gastrointestinal, lymph-nodal, visceral or peritoneal. Gall bladder (GB) is rarely involved as a primary organ in abdominal TB. On extensive research, the literature on gall bladder TB is limited to case reports. There has been no review on this rare abdominal pathology. The GB tuberculosis is difficult to diagnose preoperatively. It is a rare differential among the more common gall bladder pathologies like cholelithiasis, or a gall bladder malignancy. Standard histopathology of a resected specimen helps in this rare diagnosis. Subjecting every specimen to histopathological examination followed by medical treatment offers a chance to cure. Through this review the authors have tried to provide an insight into this entity.
Źródło:
Polish Journal of Surgery; 2018, 90, 4; 52-54
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A case of bovine tuberculosis in pigs in Poland - a country free from the disease
Autorzy:
Lipiec, M.
Radulski, L.
Szulowski, K.
Powiązania:
https://bibliotekanauki.pl/articles/2082990.pdf
Data publikacji:
2019
Wydawca:
Instytut Medycyny Wsi
Tematy:
pigs
bovine tuberculosis
eradication
Opis:
Introduction. Bovine tuberculosis is a chronic contagious disease caused by Mycobacterium bovis or Mycobacterium caprae. Before widespread action conducted in Poland between 1959–1975 to combat bovine tuberculosis (BTB), about 40% of all tuberculosis cases in pigs was caused by the bovine bacillus. At the present time, correctly carried out, long-term control of cattle has resulted in cases of bovine tuberculosis in pigs and humans being extremely rare and sporadic. In pigs, tuberculosis is most often caught in a slaughterhouse during slaughter. Materials and method. Samples came from pigs kept on the farm. Traditional bacteriological methods on solid media (Stonebrink, LJ with pyruvate) supported by the semi-automatic, liquid indicative culture method (MGIT) and PCR test were applied in targeted studies. The GenoType Mycobacterium MTBC and CM tests (Hain Lifescience, Germany) were used to additionally confirm that isolated strains classification was used. Results. Strains of mycobacteria were isolated from all examined pigs. Mycobacterium bovis was determined by real time PCR and Hain Genotype methods. Conclusions. In order to effectively fight against BTB, all animals on farms should be tested, regardless of species, while the milk of suspected cows should be utilized without being used for feed. It is important to adapt the current legal regulations to the current epidemiological situation.
Źródło:
Annals of Agricultural and Environmental Medicine; 2019, 26, 1; 29-32
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Immune response gene polymorphisms in tuberculosis
Autorzy:
Fol, Marek
Druszczynska, Magdalena
Wlodarczyk, Marcin
Ograczyk, Elzbieta
Rudnicka, Wieslawa
Powiązania:
https://bibliotekanauki.pl/articles/1038871.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
tuberculosis
susceptibility/resistance genes
Opis:
Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (M.tb), remains a leading public health problem in most parts of the world. Despite the discovery of the bacilli over 100 years ago, there are still many unanswered questions about the host resistance to TB. Although one third of the world's population is infected with virulent M.tb, no more than 5-10% develop active disease within their lifetime. A lot of studies suggest that host genetic factors determine the outcome of M.tb-host interactions, however, specific genes and polymorphisms that govern the development of TB are not completely understood. Strong evidence exists for genes encoding pattern recognition receptors (TLR, CD14), C-type lectins, cytokines/chemokines and their receptors (IFN-γ, TNF-α, IL-12, IL-10, MCP-1, MMP-1), major histocompatibility complex (MHC) molecules, vitamin D receptor (VDR), and proton-coupled divalent metal ion transporters (SLC11A1). Polymorphisms in these genes have a diverse influence on the susceptibility to or protection against TB among particular families, ethnicities and races. In this paper, we review recent discoveries in genetic studies and correlate these findings with their influence on TB susceptibility.
Źródło:
Acta Biochimica Polonica; 2015, 62, 4; 633-640
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Duodenal Tuberculosis – A Rare Case Report and Review of Literature
Autorzy:
Dahiya, Divya
Garg, Mandeep
Kaman, Lileswar
Rana, Surinder
Rao, Chalapathi
Behera, Arunanshu
Powiązania:
https://bibliotekanauki.pl/articles/1396191.pdf
Data publikacji:
2013-08-01
Wydawca:
Index Copernicus International
Tematy:
duodenal tuberculosis
duodenal obstruction
Opis:
Extrapulmonary tuberculosis is rare and often difficult to diagnose infection. We report a case of duodenal tuberculosis, who presented with upper gastrointestinal symptoms. There was evidence of obstruction in the third part of duodenum (D3) on oesophagogastro endoscopy, barium meal follow through and CT scan of abdomen. On exploration there was thickening of D3 and D4 causing luminal obstruction. Resection of stricturous segment with end-to-side duodenojejunostomy was done. Biopsy of the diseased segment was tubercular. Antitubercular treatment was given to the patient for 6 months and he is doing well on follow up (1 year after surgery). Duodenal tuberculosis being the rarest form of intestinal tuberculosis poses great difficulty in diagnosis. High index of suspicion supported by radiological investigation, exploratory laparotomy and histopathological examination of the tissue can only lead to a definitive diagnosis of this rare condition. Treatment is both surgical which involves resection or by-pass for an obstructive lesion and medical which includes antitubercular therapy
Źródło:
Polish Journal of Surgery; 2013, 85, 8; 464-466
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Płucna postać gruźlicy u 14-letniej dziewczynki – trudności diagnostyczne
Pulmonary tuberculosis in a 14-year-old girl – diagnostic difficulties
Autorzy:
Lipińska-Opałka, Agnieszka
Wawrzyniak, Agata
Kalicki, Bolesław
Jung, Anna
Koziarska, Teresa
Powiązania:
https://bibliotekanauki.pl/articles/1032945.pdf
Data publikacji:
2013
Wydawca:
Medical Communications
Tematy:
BCG
childhood tuberculosis
mycobacterium
tuberculosis treatment
gruźlica dziecięca
bcg
zapalenie płuc
prątki
leczenie gruźlicy
Opis:
Tuberculosis is still a significant clinical problem. Rate of incidence of the disease in the paediatric population is a good measure of the epidemiological situation in the area. Tuberculosis in children, always primary, is significantly different in its course from tuberculosis in adults. The most common form in children is a disease of the lung parenchyma and the clinical course may be atypical, crafty, oligosymptomatic and carried out under the guise of clinical other diseases. The diagnosis of tuberculosis in children is based on carefully collected history, clinical examination and the results of additional tests (tuberculin skin test, chest X-ray and sputum smear microscopy). Microbiological test result is the gold standard. Gastric lavage were collected to study in young children, in older – induced sputum concentrated solution of NaCl or bronchial lavage obtained during bronchoscopy. The only available vaccine against tuberculosis is BCG. In Poland, the vaccination is carried out in the first 24 hours of life for all neonates who do not have contraindications. The BCG vaccine does not protect against the disease, but only reduces the number of severe forms of tuberculosis in children. Treatment options include combination regimens consisting of two phases: a phase of intensive treatment of sterilization and a continuation phase. The article presents a case study of 14-year-old girl hospitalized in the Department of Paediatrics, Paediatric Nephrology and Allergology, because of lack of improvement in outpatient treatment of pneumonia. Due to the absence of regression of inflammatory changes on the chest radiographs and persistent auscultatory changes of the lung fields, a series of tests was performed, finally recognizing tuberculosis.
Gruźlica nadal stanowi istotny problem kliniczny. Ocena zapadalności na tę chorobę w populacji dziecięcej jest dobrym miernikiem sytuacji epidemiologicznej na danym terenie. Gruźlica dziecięca, zawsze pierwotna, znacząco różni się w swym przebiegu od gruźlicy dorosłych. Najczęstszą jej postacią u dzieci jest choroba miąższu płuc, której przebieg kliniczny może być nietypowy, podstępny, skąpoobjawowy – choroba długo może przebiegać pod maską kliniczną innych schorzeń. Rozpoznanie gruźlicy u dzieci opiera się na dokładnie zebranym wywiadzie, badaniu klinicznym oraz wynikach badań dodatkowych (tuberkulinowy test skórny, badanie radiologiczne klatki piersiowej oraz mikroskopowy rozmaz plwociny). Za złoty standard uważa się wynik badania mikrobiologicznego. U małych dzieci do badania pobierane są popłuczyny żołądkowe, u starszych plwocina indukowana stężonym roztworem NaCl lub popłuczyny oskrzelowe uzyskane podczas bronchoskopii. Jedyną dostępną szczepionką przeciwko gruźlicy jest BCG. W Polsce szczepienie wykonuje się w pierwszych 24 godzinach życia u wszystkich noworodków, u których nie stwierdza się przeciwwskazań. Szczepionka BCG nie chroni przed zachorowaniem, zmniejsza jedynie liczbę przypadków ciężkich postaci gruźlicy u dzieci. W leczeniu stosuje się skojarzone schematy, składające się z dwóch etapów: fazy intensywnego leczenia wyjaławiającego i fazy leczenia podtrzymującego. W artykule przedstawiono przypadek 14-letniej dziewczynki hospitalizowanej w Klinice Pediatrii, Nefrologii i Alergologii Dziecięcej z powodu braku poprawy leczenia ambulatoryjnego zapalenia płuc. Z uwagi na brak regresji zmian zapalnych w badaniu radiologicznym klatki piersiowej oraz utrzymujące się zjawiska osłuchowe nad polami płucnymi wykonano szereg badań, rozpoznając ostatecznie gruźlicę płuc.
Źródło:
Pediatria i Medycyna Rodzinna; 2013, 9, 3; 282-286
1734-1531
2451-0742
Pojawia się w:
Pediatria i Medycyna Rodzinna
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Tuberculosis in Polish zoos as health risk for humans
Gruźlica w polskich ogrodach zoologicznych w aspekcie zdrowia publicznego
Autorzy:
Krajewska-Wędzina, M.
Augustynowicz-Kopeć, E.
Weiner, M.
Orłowska, B.
Anusz, K.
Szulowski, K.
Powiązania:
https://bibliotekanauki.pl/articles/2052755.pdf
Data publikacji:
2017
Wydawca:
Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej
Tematy:
zoonosis
Mycobacterium tuberculosis complex
tuberculosis
public health
transmission
zoonoza
gruźlica
zdrowie publiczne
transmisja
Opis:
Introduction. Tuberculosis is an infectious disease of humans and animals caused by the organism of the Mycobacterium tuberculosis complex (MTBC). It is one of the most widespread infectious diseases occurring in zoos. Taking into account the number of visitors to these sites, tuberculosis remains a major public health problem. Material and methods. The study material consisted of lymph nodes, and internal organs collected post mortem from five zoo animals suspected of tuberculosis: antelope, two tapirs, alpaca and bison. The animals came from the zoos in Gdańsk, Wrocław and Chorzów. The microbiological analysis of 5 MTBC strains was performed to determine the molecular relationships among them. Results. Five strains were isolated in the microbiological examination, 3 of which were identified as Mycobacterium bovis and 2 − as Mycobacterium caprae. 3 spoligotypes, i.e. SB1912, SB0856, SB2416, were obtained by spoligotyping. To confirm the transmission of tuberculosis in the studied animal population, the MIRU-VNTR method was applied. The unique patterns were assigned to 3 strains and the other 2 of the same pattern were assigned to one cluster, which would indicate the transmission of tuberculosis among animals. Conclusions. The obtained results exclude the transmission of tuberculosis between zoos.
Wprowadzenie. Gruźlica jest zakaźną chorobą ludzi i zwierząt, którą powodują prątki wchodzące w skład kompleksu Mycobacterium tuberculosis (MTBC). Jest jedną z najbardziej rozpowszechnionych chorób zakaźnych występujących w zoo. Biorąc pod uwagę liczbę odwiedzających te miejsca, gruźlica stanowi niebezpieczeństwo dla zdrowia publicznego. Materiał i metody. Materiał do badań stanowiły węzły chłonne i narządy wewnętrzne pobrane post mortem od pięciu zwierząt z zoo podejrzanych o gruźlicę: antylopy, dwóch tapirów anta, alpaki i żubra. Zwierzęta pochodziły z zoo w Gdańsku, Wrocławiu i Chorzowie. W pracy poddano analizie mikrobiologicznej 5 szczepów MTBC i określono pokrewieństwo molekularne pomiędzy nimi. Wyniki. W wyniku badania mikrobiologicznego wyizolowano 5 szczepów, 3 zidentyfikowano jako M. bovis a 2 jako M. caprae. Metodą spoligotyping uzyskano 3 spoligotypy (SB1912, SB0856, SB2416). Do potwierdzenia zjawiska transmisji gruźlicy w badanej populacji zwierząt, zastosowano metodę MIRU-VNTR. Wzory unikalne przyporządkowano 3 szczepom, a pozostałe 2 szczepy o takich samych wzorach zostały przydzielone do wspólnego klasteru świadczącego o zaistniałej transmisji prątków gruźlicy pomiędzy zwierzętami. Wnioski. Uzyskane wyniki pozwoliły wykluczyć transmisję gruźlicy między ogrodami zoologicznymi.
Źródło:
Health Problems of Civilization; 2017, 11, 4; 233-238
2353-6942
2354-0265
Pojawia się w:
Health Problems of Civilization
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-25 z 98

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