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Wyszukujesz frazę "Marine actinomycetes" wg kryterium: Temat


Wyświetlanie 1-3 z 3
Tytuł:
Diversified role and applications of marine actinomycetes in the field of biology
Autorzy:
Rasool, Ubaid
Hemalatha, S.
Powiązania:
https://bibliotekanauki.pl/articles/1179574.pdf
Data publikacji:
2017
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Biofouling
Marine actinomycetes; Biologically active metabolites
Nanoparticles
Novel compounds
Resistant pathogenic microorganisms
Opis:
Actinomycetes are the most profitable and biotechnologically valued prokaryotes representing the genera consisting of Streptomyces, Arthrobacter, Actinomyces, Cornyebacterium, Micrococcus, Micromonospora and other diverse species of microorganisms. Actinomycetes represent a group of one of the most powerful secondary metabolite producers which possess a wide range of biological activities. Streptomyces, an important genus under actinomycetes, alone serves as the huge producer of a number of biologically active molecules. This genus possesses a huge potential of synthesizing various different and novel active metabolites. Due to the gradual reduction of the chances of isolation of novel compounds within Streptomyces coming from terrestrial environs resulting in the increase of resistant pathogenic microorganisms, marine actinomycetesmay form a platform for novel drug synthesis, which in-turn may form an extraordinary tool for combating a wide range of resistant microbes. The role of marine actinomycetes extends to diverse fields such as antibiotic production, production of antibacterial and antifungal compounds, synthesis of enzymes and enzyme inhibitors, synthesis of anticancer drugs and various other lifesaving molecules. Marine actinomycetes also play an important role in biofouling and nanoparticle synthesis. Thus speakingsuccinctly, marine actinomycetes are biologically very important as they serve their useful purpose in various fields of biology.
Źródło:
World Scientific News; 2017, 74; 1-14
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
SCREENING THE SPECIFIC SUBSTRATES OF ADENYLATION DOMAIN FROM MARINE ACTINOMYCETES BY FLUORESCENCE QUENCHING AND ISOTHERMAL TITRATION CALORIMETRY
Autorzy:
LEI, MING
ZHAO, ZHIJUAN
LIU, KE
LIU, YANLI
ZHANG, HUI
WU, XUE
GONG, SIYING
MA, YANLING
ZHAO, HAOBIN
LIU, JINLIN
MIN, JINRONG
QI, CHAO
Powiązania:
https://bibliotekanauki.pl/articles/895432.pdf
Data publikacji:
2018-12-31
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
A domain
Aspartic acid
Fluorescence quenching (FQ)
Isothermal titration calorimetry (ITC)
Marine actinomycetes
static quenching
Opis:
Adenylation domain (A domain) is a model of non-ribosomal peptide synthetases (NRPs), responsible for binding and activating the substrates-amino acids. In this study, a pGEX-2T-sare0718 recombinant plasmid (the gene sare0718 was cloned from Salinispora arenicola CNS-205, S.arenicola CNS-205) was transformed and expressed as a protein GST-Sare0718. Fluorescence quenching (FQ) was conducted to investigate the binding of 20 common amino acids to GST-Sare0718, then isothermal titration calorimetry (ITC) also be used[changed]. The results of FQ revealed that intrinsic fluorescence of GST-Sare0718 is quenched steadily by addition of aspartic acid (Asp) and glutamine (Gln) through static quenching mechanism. The binding constants Ka are Asp (1.504×106 L/mol) ≥ Gln (1.468×105 L/mol). And there is one binding site on the protein GST-Sare0718. We confirmed Asp preference of GST-Sare0718 by ITC. Therefore, Asp is the specific substrate. In addition, the experimental data indicates that the prediction system, “the specificity-conferring code”, is not suitable for marine actinomycetes. So it is urgent to set up a special predictive system for marine actinomycetes.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 6; 1287-1292
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Production of bioactive metabolites from different marine endophytic Streptomyces species and testing them against methicillin-resistant Staphylococcus aureus (MRSA) and cancer cell lines
Autorzy:
El-Gendy, M.M.A.A.
Mohamed, Z.K.
Hekal, N.Z.
Ali, F.M.
Yousef, A.E.M.
Powiązania:
https://bibliotekanauki.pl/articles/81078.pdf
Data publikacji:
2018
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Staphylococcus aureus
infection
methicillin-resistant Staphylococcus aureus
endophyte
Streptomyces
bioactive metabolite
Actinomycetes
marine invertebrate
anticancer activity
cancer cell line
lung cancer
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2018, 99, 1
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-3 z 3

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