- Tytuł:
- Synthesis, biological investigations, QSAR and DFT analysis of sulfonamide chalcones as potential: antimicrobial, antifungal and antimalarial agents
- Autorzy:
-
Meena, Lakshman R.
Sharma, Vinay S.
Swarnkar, Pawan - Powiązania:
- https://bibliotekanauki.pl/articles/1031835.pdf
- Data publikacji:
- 2020
- Wydawca:
- Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
- Tematy:
-
Claisen-Schmidt condensation
antifungal
antimalarial
antimicrobial
sulfonamide hybrids
α-β-unsaturated ketone - Opis:
- Various aromatic aldehydes condense with aryl ketone (N-(4-(phenylsulfonamido)phenyl) acetamide) in presence of aqueous alkaline NaOH to form α, β-unsaturated ketone (N-(4-(N-phenylsulfamoyl)phenyl)cinnamamide derivatives or sulfonamide chalcone derivatives). We were synthesized novel sulfonamides chalcones synthesized through Claisen-Schmidt condensation of aromatic aldehydes and sulfonamide containing acetanilide. All the synthesized compounds were characterized using Mass, FTIR, NMR (1H & 13C) spectra analysis. The synthesized sulfonamide chalcone hybrids were screened antimicrobial activity, antifungal and antimalarial activity.
- Źródło:
-
World Scientific News; 2020, 147; 179-196
2392-2192 - Pojawia się w:
- World Scientific News
- Dostawca treści:
- Biblioteka Nauki
Artykuł