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Tytuł:
The Appearance of Life
Autorzy:
Krzymowski, Richard
Ługowski, Włodzimierz
Powiązania:
https://bibliotekanauki.pl/articles/42563036.pdf
Data publikacji:
2024
Wydawca:
Polska Akademia Nauk. Instytut Filozofii i Socjologii PAN
Tematy:
Biogenesis
chemical evolution
pre-biological natural selection
Opis:
The article presents the hypothesis of the origin of life. All the basic ideas of the 20th century research program in this area can be found there: the extrapolation of Darwinism into the area of chemical evolution, the influence of solar energy, the large “chemical possibilities” of carbon compounds, early heterotrophy, the gradual increase of organic purpose as a result of natural selection.
Źródło:
Filozofia i Nauka; 2024, 12; 43-54
2300-4711
2545-1936
Pojawia się w:
Filozofia i Nauka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Prohibitins and Ras2 protein cooperate in the maintenance of mitochondrial function during yeast aging.
Autorzy:
Kirchman, Paul
Miceli, Michael
West, Roger
Jiang, James
Kim, Sangkyu
Jazwinski, S
Powiązania:
https://bibliotekanauki.pl/articles/1043375.pdf
Data publikacji:
2003
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
ROS
retrograde response
Saccharomyces cerevisiae
longevity
mitochondrial biogenesis
Opis:
The yeast Saccharomyces cerevisiae has a finite replicative life span. Yeasts possess two prohibitins, Phb1p and Phb2p, in similarity to mammalian cells. These proteins are located in the inner mitochondrial membrane, where they are involved in the processing of newly-synthesized membrane proteins. We demonstrate that the elimination of one or both of the prohibitin genes in yeast markedly diminished the replicative life span of cells that lack fully-functional mitochondria, while having no effect on cells with functioning mitochondria. This deleterious effect was suppressed by the deletion of the RAS2 gene. The expression of PHB1 and PHB2 declined gradually up to 5-fold during the life span. Cells in which PHB1 was deleted in conjunction with the absence of a mitochondrial genome displayed remarkable changes in mitochondrial morphology, distribution, and inheritance. This loss of mitochondrial integrity was not seen in cells devoid of PHB1 but possessing an intact mitochondrial genome. In a subset of the cells, the changes in mitochondrial integrity were associated with increased production of reactive oxygen species, which co-localized with the altered mitochondria. The mitochondrial deficits described above were all suppressed by deletion of RAS2. Our data, together with published information, are interpreted to provide a unified view of the role of the prohibitins in yeast aging. This model posits that the key initiating event is a decline in mitochondrial function, which leads to progressive oxidative damage that is exacerbated in the absence of the prohibitins. This aggravation of the initial damage is ameliorated by the suppression of the production of mitochondrial proteins in the absence of Ras2p signaling of mitochondrial biogenesis.
Źródło:
Acta Biochimica Polonica; 2003, 50, 4; 1039-1056
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
On the Theory of Prebiotic Evolution
Autorzy:
Rudenko, Alexander Prokofievich
Ługowski, Włodzimierz
Powiązania:
https://bibliotekanauki.pl/articles/42565016.pdf
Data publikacji:
2024
Wydawca:
Polska Akademia Nauk. Instytut Filozofii i Socjologii PAN
Tematy:
biogenesis
theory of evolution of open catalytic systems
Opis:
The main theorems of the theory of evolution of open catalytic systems are briefly presented. The difference between the “natural-historical” and “actualistic” approach to the problem of the origins of life was highlighted.
Źródło:
Filozofia i Nauka; 2024, 12; 83-88
2300-4711
2545-1936
Pojawia się w:
Filozofia i Nauka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Chromoplast biogenesis in Chelidonium majus petals
Autorzy:
Prebeg, T
Ljubesic, N.
Wrischer, M.
Powiązania:
https://bibliotekanauki.pl/articles/57510.pdf
Data publikacji:
2006
Wydawca:
Polskie Towarzystwo Botaniczne
Tematy:
chromoplast
biogenesis
Chelidonium majus
petal
greater celandine
fibrillin
ultrastructure
Opis:
The differentiation of chromoplasts, with special emphasis on the formation and the organisation of chromoplast fibrils, was followed in the petals of the greater celandine, Chelidonium majus L. Electron microscopic observations showed that, in the epidermis, differentiation of chromoplasts started from leucoplasts, while mesophyll chromoplasts originated from chloroplasts. During petal maturation, fibrils accumulated in the plastids, often arranging in a parallel fashion to form compact birefringent bundles. Immediately before flower opening, these fibrillar bundles started to disorganise, and, at anthesis, most chromoplasts contained widely spaced fibrils which were irregularly dispersed through the plastid interior. During chromoplast differentiation, fibrils were commonly observed to protrude from plastoglobules, suggesting the possible site of their formation. Western analysis indicated that a protein antigenically related to fibrillin from pepper chromoplasts participates in the constitution of fibrils in Chelidonium petals.
Źródło:
Acta Societatis Botanicorum Poloniae; 2006, 75, 2; 107-112
0001-6977
2083-9480
Pojawia się w:
Acta Societatis Botanicorum Poloniae
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Nuclear and mitochondrial genome responses in HeLa cells treated with inhibitors of mitochondrial DNA expression
Autorzy:
Piechota, Janusz
Szczęsny, Roman
Wolanin, Kamila
Chlebowski, Aleksander
Bartnik, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1041204.pdf
Data publikacji:
2006
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
thiamphenicol
mtDNA depletion
HeLa
dideoxycytidine
mitochondrial biogenesis
ethidium bromide
Opis:
The influence of mutations in the mitochondrial DNA (mtDNA) on the bioenergetic metabolism of the cell is still poorly understood. Many of the mutations in the mtDNA affect the expression of the mitochondrial genome. Investigations on cells from patients are not easy, especially as the mitochondrial DNA is heteroplasmic and this state is changed in culture. Moreover, the nuclear background and the mitochondrial haplotype may affect the behaviour of cells. Transfer of patient mitochondria to rho zero cell lines is also not optimal as these cells in general have many nuclear changes which may also affect cell behaviour. Thus, we decided to use inhibitors of mitochondrial genome expression, such as thiamphenicol, ethidium bromide and dideoxycytidine to investigate the bioenergetic metabolism of HeLa cells. We found that oxidative phosphorylation and glycolysis participate equally in ATP production in HeLa cells and that decreased activity of the respiratory chain leads to increased glycolysis and the reduction of cell growth. Insufficient ATP production in the oxidative phosphorylation process was not compensated by increased proliferation of the mitochondria. However, we were able to show that there are some mechanisms compensating limited expression of the mitochondrial genome within the mitochondria. Experiments with dideoxycytidine revealed that 10-fold decrease of the mtDNA copy number resulted in almost normal activity of cytochrome c oxidase. We found that mtDNA depletion is compensated mostly on the level of RNA metabolism in the mitochondria. Thus, our results are in agreement with the hypothesis that transcription initiation rather than mtDNA copy number is a rate limiting factor for expression of the mitochondrial genome.
Źródło:
Acta Biochimica Polonica; 2006, 53, 3; 485-495
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Discrete dynamic system oriented on the formation of prebiotic dipeptides from Rodes experiment
Autorzy:
Polanco, Carlos
Samaniego, José
Buhse, Thomas
Castañón González, Jorge
Powiązania:
https://bibliotekanauki.pl/articles/1039201.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
origins of life
biogenesis
dipeptides
salt-induced peptide formation
Opis:
This work attempts to rationalize the possible prebiotic profile of the first dipeptides of about 4 billion years ago based on a computational discrete dynamic system that uses the final yields of the dipeptides obtained in Rode's experiments of salt-induced peptide formation (Rode et al., 1999, Peptides 20: 773-786). The system built a prebiotic scenario that allowed us to observe that (i) the primordial peptide generation was strongly affected by the abundances of the amino acid monomers, (ii) small variations in the concentration of the monomers have almost no effect on the final distribution pattern of the dipeptides and (iii) the most plausible chemical reaction of prebiotic peptide bond formation can be linked to Rode's hypothesis of a salt-induced scenario. The results of our computational simulations were related to former simulations of the Miller, and Fox & Harada experiments on amino acid monomer and oligomer generation, respectively, offering additional information to our approach.
Źródło:
Acta Biochimica Polonica; 2014, 61, 4; 717-726
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synthesis of Zinc oxide nanoparticles from Clitoria ternatea L. extracts: a green approach
Autorzy:
Manokari, M.
Shekhawat, Mahipal S.
Powiązania:
https://bibliotekanauki.pl/articles/1189980.pdf
Data publikacji:
2016
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Biogenesis
Zinc oxide nanoparticles
Clitoria ternatea
UV-Visible characterization
Opis:
We report the development of green methods for synthesis of zinc oxide at nano scale. Biological systems are being explored for the synthesis of nanoparticles. The plant Clitoria ternatea contains alkaloids, tannins, glycosides, resins, steroids, saponins, flavonoids, phenols, kaempferol, clitorin, taraxerol, aparajitin, sistosterol, hexacosanal and anthoxanthin. The whole plant is traditionally used to treat leprosy, bronchitis, inflammation, leucoderma and tuberculosis. The present report describes the biosynthesis and characterization of zinc oxide nanoparticles using aqueous extracts of leaves, stem, root, flowers and fruits of Clitoria ternatea. The aqueous reaction mixture of leaf, flower petals and roots showed strong broad UV spectral peak at 296 nm, stem at 293 nm and roots at 311 nm.
Źródło:
World Scientific News; 2016, 52; 216-227
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Nowożytne przemiany idei samorództwa
Modern Transformations of the Idea of Autogeny
Autorzy:
Świeżyński, Adam
Powiązania:
https://bibliotekanauki.pl/articles/2013051.pdf
Data publikacji:
2009
Wydawca:
Katolicki Uniwersytet Lubelski Jana Pawła II. Towarzystwo Naukowe KUL
Tematy:
biogeneza
samorództwo
mechanicyzm
witalizm
mikroorganizmy
biogenesis
autogeny
mechanicism
vitalism
microorganisms
Opis:
Autogeny, sometimes also called “naïve”, spontaneous generation (Lat. generatio spontanea) is – most generally speaking – a view, according to which living creatures come into being spontaneously and voluntarily from inanimate matter. Such a broad formulation of the idea of autogeny, however, does not show significant differences that occur in understanding it. The basis for these differences is constituted by different definitions of what should be considered inanimate matter, and what – animate matter. A thorough consideration of the arguments that have been offered in the history of research into the nature in order to justify the idea of autogeny, and an investigation into the modern debates and controversies concerning this idea allow discovering a variety of interpretations of the view of a spontaneous and voluntary origin of biological organisms. The variety was formed together with the development of the scientific empirical method and with the participation of philosophical concepts explaining the way the animate world functions. With time, the idea of a spontaneous origin of organisms underwent many transformations, first consisting in limiting the range of its application (from macroscopic organisms with complex structure to relatively simple microorganisms), then in a change in its understanding, and finally to questioning the very idea. Also the way changed, in which the possibility of the occurrence of autogeny in the nature was motivated. However, it seems that the very core of the idea of autogeny, which contains a general thought about transformation of matter leading to the origin of living organisms is still maintained in the contemporary natural science.
Źródło:
Roczniki Filozoficzne; 2009, 57, 1; 195-229
0035-7685
Pojawia się w:
Roczniki Filozoficzne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Tytan versus enceladus, czyli o mnogości teorii biogenezy i świadomości filozoficznej uczonych
Tytan versus enceladus — on the multitude of theories of biogenesis and on the philosophical awareness of scientists
Autorzy:
Kubica, Alicja
Powiązania:
https://bibliotekanauki.pl/articles/41182696.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Instytut Filozofii i Socjologii PAN
Tematy:
theoretical synthesis
biogenesis
popular science
biogeneza
synteza teoretyczna
popularyzacja wiedzy
Opis:
Niniejszy tekst powstał na podstawie wywiadów przeprowadzonych z uczonymi Caltechu (Pasadena, USA) w 2018 roku. Rozmowy dotyczyły typów współczesnych teorii biogenezy oraz roli przesłanek filozoficznych w nich przyjmowanych. Badacze odnieśli się także do problematyki popularyzacji nauki. Światopogląd naukowy kształtowany jest bowiem (oraz utrwalany) przez publikacje popularyzatorskie. Odpowiedzieli również na pytania odnoszące się do osobistych przekonań dotyczących początków życia na Ziemi oraz wpływu tychże na pracę ich samych a także grup badawczych, do których należą.
The text was created on the basis of interviews with Caltech scholars (Pasadena, USA) in 2018. The talks concerned various contemporary theories of biogenesis and the role of their philosophical premises. The researchers also addressed the issue of popularizing science. The worldview is shaped (and established) by popularizing publications. They also answered the questions how their personal beliefs influenced on research.
Źródło:
Filozofia i Nauka; 2019, 7, 2; 191-202
2300-4711
2545-1936
Pojawia się w:
Filozofia i Nauka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Human ribonuclease Dicer inhibition using RNA aptamers
Autorzy:
Tyczewska, A.
Powiązania:
https://bibliotekanauki.pl/articles/80081.pdf
Data publikacji:
2014
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
ribonuclease
ribonuclease Dicer
aptamer
SELEX method
microRNA
biogenesis
enzyme activity
patent
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2014, 95, 4
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
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