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Tytuł:
Synthesis, antiprotozoal and antibacterial activity of nitro- and halogeno-substituted benzimidazole derivatives.
Autorzy:
Kazimierczuk, Zygmunt
Upcroft, Jacqueline
Upcroft, Peter
Górska, Agata
Starościak, Bohdan
Laudy, Agnieszka
Powiązania:
https://bibliotekanauki.pl/articles/1043825.pdf
Data publikacji:
2002
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
antibacterial activity
antiprotozoal activity
benzimidazoles
Opis:
Two series of benzimidazole derivatives were sythesised. The first one was based on 5,6-dinitrobenzimidazole, the second one comprises 2-thioalkyl- and thioaryl-substituted modified benzimidazoles. Antibacterial and antiprotozoal activity of the newly obtained compounds was studied. Some thioalkyl derivatives showed remarkable activity against nosocomial strains of Stenotrophomonas malthophilia, and an activity comparable to that of metronidazole against Gram-positive and Gram-negative bacteria. Of the tested compounds, 5,6-dichloro-2-(4-nitrobenzylthio)-benzimidazole showed the most distinct antiprotozoal activity.
Źródło:
Acta Biochimica Polonica; 2002, 49, 1; 185-195
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Nanosilver - does it have only one face?
Autorzy:
Likus, Wirginia
Bajor, Grzegorz
Siemianowicz, Krzysztof
Powiązania:
https://bibliotekanauki.pl/articles/1039429.pdf
Data publikacji:
2013
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
silver nanoparticles
antibacterial activity
toxicology
Opis:
Silver nanoparticles (NPs) have at least one dimension of a particle smaller than 100 nm and contain 20-15,000 silver atoms. Due to its antibacterial activity nanosilver (NS) is used for medical purposes. NS particles can be obtained by various methods. Potentially, the best method of the NS synthesis for medical purposes is based on a brief flow of electric current between two silver electrodes placed in deionized water. It is accepted that the major antibacterial effect of silver is its partial oxidation and releasing silver ions, which interact with thiol groups of peptidoglicans of bacterial cell wall, and proteins of the cell membrane causing cell lysis. Silver ions can also bind to bacterial DNA preventing its replication and stopping synthesis of bacterial proteins. The rise in exposure to silver NPs has spurred interest into their toxicology. NS undergoes a set of biochemical transformations including accelerated oxidative dissolution in gastric acid, binding to thiol groups of serum and tissue proteins, exchange between thiol groups, sulfides and selenides, binding to selenoproroteins and photoreduction in skin to zerovalent metallic silver. Animal studies have shown that exposure to NS may lead to liver and spleen damage. NS can also stimulate an increased secretion of proinflammatory cytokines by monocytes. As a spectrum of NS applications is still growing, the complex evaluation of a safety of its use becomes an important task. This requires an elucidation of not only the influence of NS on human cells and organism, but also its biotransformation in organism and in environment.
Źródło:
Acta Biochimica Polonica; 2013, 60, 4; 495-501
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Biomaterials with antibacterial activity
Autorzy:
Wysocka, K.
Buzalewicz, I.
Wieliczko, A.
Kowal, K.
Stręk, W.
Podbielska, H.
Powiązania:
https://bibliotekanauki.pl/articles/284386.pdf
Data publikacji:
2008
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
biomaterials
silver nanoparticles
antibacterial activity
Opis:
The sol-gel derived silica spheres with surfaces modified by silver nanoparticles were used to enhance the photodynamic effect. The silica nanoparticles were prepared by modified Stöber synthesis. The diameter of obtained silica spheres was ca. 100 nm. These silica spheres we used as a carrier for noble nanoparticles. It was shown that Ag-Au nanoparticles have an antibacterial activity against Escherichia coli. This effect depends on the nanoparticles concentration and it is stronger for higher concentrations. Laser irradiation enhances this effect, and starting from certain concentration it is possible to kill Escherichia coli, totally, when using laser light.
Źródło:
Engineering of Biomaterials; 2008, 11, no. 81-84; 119-121
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Formation and properties of dbc/pla microfibres
Autorzy:
Biniaś, Dorota
Biniaś, Włodzimierz
Machnicka, Alicja
Janicki, Jarosław
Hałuszka, Patrycja
Powiązania:
https://bibliotekanauki.pl/articles/1034598.pdf
Data publikacji:
2017
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
PLA
antibacterial activity
dibutyrylchitin
electrospinning
microfibres
Opis:
In this study, a solution of dibutyrylchitin (DBC)/polylactide (PLA) blend micro and nanofibres were successfully fabricated using blends of 2,2,2-trifluoroethanol (TFE) as solvents. Fibres were produced from the solutions by electrospinning. The DBC/PLA blend solutions in various ratios were studied for electrospinning into micro/nanofibres. The morphology of the micro and nanofibres was observed by scanning electron microscope (SEM). The biggest diameters of DBC/PLA fibres were obtained for the blended microfibres in ratios of 10/90 and 25/75. The smallest diameter was observed for pure polymers. The antibacterial properties were examined for materials obtained by electrospinning. In the experiments, materials with antibacterial properties were made. It is likely that the electrospun micro and nanofibres will be used in the native extracellular matrix for tissue engineering.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2017, 22; 5-13
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Highly developed construction of Heterostructured InWO3-InMoO3 loaded-TiO2 nanomaterial and Expanding multi-application
Autorzy:
Kamalakkannan, J.
Senthilvelan, S.
Powiązania:
https://bibliotekanauki.pl/articles/1178704.pdf
Data publikacji:
2017
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
HR-TEM
Photocatalytic
antibacterial activity
electrochemical study
Opis:
InWO3-InMoO3 loaded-TiO2 nanomaterial was synthesised by co-precipitation method and sonication technique. The nanomaterial was characterized by High-resolution scanning electron microscopy (HR-SEM) with elementary dispersive X-ray (EDX), High-resolution transmission electron microscopy (HR-TEM), photoluminescence spectroscopy (PL) and UV-Vis diffuse reflectance spectroscopy (DRS). The photocatalytic activity of InWO3-InMoO3 loaded-TiO2 nanomaterial was studied from the photodegradation of methyl green (MEG) and methylene blue (MB) under UV-light irradiation at 365 nm. The hydroxyl radical formation in the mechanism was confirmed by fluorescence quenching technique. The mineralization confirmed by chemical oxygen demand measurements. A flaxisible mechanism is proposed for higher catalytic activity of InWO3-InMoO3-TiO2 under UV-light for 365 nm. This catalyst was found to be stable and reusable without appreciable loss of catalytic activity up to five cycles. The InWO3- InMoO3 loaded-TiO2 nanomaterial on MEG was high photocatalytic activity that of MB so high photocatalytic activity has been discussed by first order kinetics, rate constant value and high quantum yield. This material was showed increased hydrophobicity that of TiO2 electrochemical study and antibacterial activity of the analysis was also studied.
Źródło:
World Scientific News; 2017, 67, 2; 338-364
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synthesis and antimicrobial activity of substituted (E)-1-(4-fluoro-3-methylphenyl)-3-phenylprop-2-en-1-one compounds
Autorzy:
Balaji, S.
Senbagam, R.
Rajarajan, M.
Vijayakumar, R.
Manikandan, V.
Vanangamud, G.
Thirunarayanan, G.
Powiązania:
https://bibliotekanauki.pl/articles/1189942.pdf
Data publikacji:
2016
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Antibacterial activity
Antifungal activity
Bacillus subtilis
vibrio cholera
Opis:
In an effort to develop antimicrobial agents, a series of substituted (E)-1-(4-fluoro-3-methylphenyl)-3-phenylprop-2-en-1-one compounds were synthesized by crossed-aldol condensation reaction of 4-fluoro-3-methyl acetophenone with various substituted benzaldehydes in the presence of sodium hydroxide. The synthesized compounds were characterized by means of their UV, IR and NMR spectral data. The synthesized substituted (E)-1-(4-fluoro-3-methylphenyl)-3-phenylprop-2-en-1-one compounds were tested for their antibacterial and antifungal activities by the Bauer-Kirby disc diffusion method.
Źródło:
World Scientific News; 2016, 52; 14-30
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of the phenolic contents and antibacterial activity of different concentrations of Onosma chlorotricum Boiss
Autorzy:
Dousti, B.
Nabipor, F.
Powiązania:
https://bibliotekanauki.pl/articles/2096818.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
phenolic compounds
flavonoids
antibacterial activity
Onosma chlorotricum
Opis:
Because of side effects and increasing resistance to antibiotics, considerable attention hasbeen given to extract sand biologically active compounds isolated from medicinal plants. In the present study, phytochemical screening and antibacterial activities of different concentrations of various extracts of Onosma chlorotricum were evaluated and compared with those of vancomycin and amikacin. Total phenolic and flavonoid contents and the antibacterial activity of methanol, n-hexane, and aqueous extracts (5 mg/ml to 0.156 mg/ml final concentration) of O. chlorotricum against Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli were evaluated using disc diffusion and microdilution methods. Total phenolic and flavonoid contents were determined according to the Folin-Ciocalteu and aluminum chloride colorimetric assays, respectively. The results showed that the total phenolic and flavonoid contents of these extracts ranged from 56.10 ± 0.13 to 74.12 ± 0.05 mg GAE/g dry extract and from 19.3 ± 0.6 to 23.20 ± 0.41 mg QE/g dry extract, respectively. The methanol extract with the highest phenolic and flavonoid content showed the highest antibacterial activity against all the tested bacterial strains, with the highest inhibition zone of 21 ± 0.7 mm and the lowest MIC and MBC values of 78.12 μg/ml for S. aureus. The antibacterial effects and the total phenolic content of O. chlorotricum were remarkable. The results suggest that the effects of methanol extract on wound healing could be tested in an animal model.
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2021, 102, 4; 377-386
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Biological activities and chemical composition of solvent extracts of Stoechospermum marginatum (C. Agardh)
Autorzy:
Esmaeili, Akbar
Khakpoor, Marjan
Powiązania:
https://bibliotekanauki.pl/articles/1039656.pdf
Data publikacji:
2012
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
brown seaweed
antibacterial activity
Stoechospermum marginatum
extract
antioxidant activity
Opis:
The objective of this study was to evaluate the chemical composition CH3OH-CH2Cl2 (1:1) extract and biological activities of various extracts derived from the aerial parts of the brown marine alga Stoechospermum marginatum (C. Agardh). Gas chromatography (GC) and gas chromatography-mass spectroscopy (GC-MS) were used to analyze the composition of the essential oil. Total phenolics assay demonstrated a high value in hexane extract (HE), with a lower value for chloroform extract (CE), and the lowest value for methanol extract (ME). DPPH (2,2-diphenyl-1-picrylhydrazyl) assay showed that extracts of S. marginatum possess radical scavenging activity (RSA). Tests of the antioxidant property of the extracts revealed both electron and hydrogen transfer mechanisms. The antibacterial activity of the ME, CE, and HE as well as an ethanol extract was estimated against seven Gram-positive and Gram-negative bacteria. The ethanol extract showed the highest antibacterial activity, and the HE showed the lowest.
Źródło:
Acta Biochimica Polonica; 2012, 59, 4; 581-585
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antibacterial Activities of Some Schiff Bases Involving Thiosemicarbazide and Ketones
Autorzy:
Shariar, S. M. S.
Jesmin, M.
Ali, M. M.
Powiązania:
https://bibliotekanauki.pl/articles/412294.pdf
Data publikacji:
2014
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
antibacterial activity
Minimum inhibitory concentration
Brine shrimp lethality
Opis:
Three Schiff bases derived from thiosemicarbazide and ketones (Vanillin, Benzophenone and Acetophenone) were used to study their antibacterial activities against some pathogenic bacteria by disc diffusion method. Of these, benzophenone thiosemicarbazone showed significant antibacterial activity as compared with that of Kanamycin. All these three compounds were found to possess cytotoxic effect. Minimum inhibitory concentration of these compounds was also determined.
Źródło:
International Letters of Chemistry, Physics and Astronomy; 2014, 7; 53-61
2299-3843
Pojawia się w:
International Letters of Chemistry, Physics and Astronomy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Aktywność przeciwbakteryjna in vitro wytworzonych bioszkieł zawierających srebro
In vitro antibacterial activity of silver-containing bioglasses
Autorzy:
Ciołek, L.
Karaś, J.
Olszyna, A.
Zaczyńska, E.
Czarny, A.
Żywicka, B.
Powiązania:
https://bibliotekanauki.pl/articles/285884.pdf
Data publikacji:
2010
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
bioszkło
działania przeciwbakteryjne
srebro
bioglasses
antibacterial activity
silver
Źródło:
Engineering of Biomaterials; 2010, 13, no. 99-101; 21-23
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
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