Temat: AMPA - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Pesticides in Small Agricultural Catchments in the Czech Republic
Autorzy:: Konečná, Jana
Zajíček, Antonín
Sáňka, Milan
Halešová, Taťána
Kaplická, Markéta
Nováková, Eva
Powiązania:: https://bibliotekanauki.pl/articles/24201794.pdf
Data publikacji:: 2023
Wydawca:: Polskie Towarzystwo Inżynierii Ekologicznej
Tematy:: soil
sediment
water
glyphosate
AMPA
parent pesticides
metabolites
Opis:: Generally, pesticides are the products containing at least one chemical substance which should protect plant or plant products against pests/diseases. Among them, the most important ones are herbicides, followed by insecticides and fungicides. As a result of intensive agriculture techniques, large amounts of pesticides are applied on agricultural soil. They remain and degrade in soil, but they can enter water bodies and negatively affect water quality and the aquatic ecosystem. The article deals with the level of pesticide load in soil, bottom sediment and surface water in chosen agriculture catchments in the Czech Republic. Results revealed that the main general problem is glyphosate and its metabolite AMPA, although their application has been constrained for several years. Furthermore, the difference in contents of chosen parent pesticide substances and their metabolites in soils and waters were pointed out.
Źródło:: Journal of Ecological Engineering; 2023, 24, 3; 99--112
2299-8993
Pojawia się w:: Journal of Ecological Engineering
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Screening of chromosomal region 21q22.3 for mutations in genes associated with neuronal Ca2+ signalling in bipolar affective disorder
Autorzy:: Kostyrko, Andrzej
Hauser, Joanna
Rybakowski, Janusz
Trzeciak, Wiesław
Powiązania:: https://bibliotekanauki.pl/articles/1041245.pdf
Data publikacji:: 2006
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: TRPM2 protein
AMPA glutamate receptor B
bipolar affective disorder
Opis:: The therapeutic effect of lithium in bipolar affective disorder may be connected with decreasing intracellular Ca2+ concentrations. Several linkage studies have identified a potential bipolar affective disorder susceptibility locus within chromosomal region 21q22.3. This locus contains two genes expressed in the brain - ADARB1 and TRPM2 - involved in regulating intracellular Ca2+ concentrations. The aim of this study was an identification of mutations in the coding sequences of ADARB1 and TRPM2 and their association with bipolar affective disorder. For that purpose we screened 60 patients with bipolar affective disorder and a control group of 66 subjects using single strand conformation polymorphism and sequence analysis. For rapid screening we performed restriction fragment length polymorphism analysis. Screening of bipolar affective disorder patients for mutations in TRPM2 led to identification of three novel and four known transitions. Two transitions resulted in the substitutions: R755C and A890V. Screening of the coding sequence of ADARB1 did not reveal any mutations except one already known transition. A comparison of the transition frequency in patients and controls does not support association of the detected mutations with bipolar affective disorder. According to our results, bipolar affective disorder may not be caused by mutations in ADARB1. However, this study does not exclude TRPM2 as a candidate gene since we have screened only about 30 per cent of the entire coding sequence of this large gene.
Źródło:: Acta Biochimica Polonica; 2006, 53, 2; 317-320
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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