- Tytuł:
- In vitro effects of compounds isolated from Sideritis brevibracteata on bovine kidney cortex glutathione reductase
- Autorzy:
-
Tandogan, Berivan
Güvenç, Ayşegül
Çalış, İhsan
Ulusu, Nuriye - Powiązania:
- https://bibliotekanauki.pl/articles/1039826.pdf
- Data publikacji:
- 2011
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
inhibition
glutathione reductase
Sideritis brevibracteata
kinetic
8-hydroxyflavone glycosides - Opis:
- Glutathione reductase (GR, E.C 1.6.4.2) is a flavoprotein that catalyzes NADPH-dependent reduction of oxidized glutathione (GSSG) to reduced glutathione (GSH). The aim of this study was to investigate in vitro effects of phenolic compounds isolated from Sideritis brevibracteata on bovine kidney GR. The Sideritis species are widely found in nature and commonly used as medicinal plants. 7-O-glycosides of 8-OH-flavones (hypolaetin, isoscutellarein and 3'-hydroxy-4'-O-methylisoscutellarein) were isolated from aerial parts of Sideritis brevibracteata. These compounds inhibited bovine kidney cortex GR in a concentration-dependent manner. Kinetic characterization of the inhibition was also performed.
- Źródło:
-
Acta Biochimica Polonica; 2011, 58, 4; 471-475
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł