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    Wyświetlanie 1-14 z 14
    Tytuł:
    COMBINATION OF BERBERINE AND MATRINE AFFECTS APOPTOSIS AND CELLCYCLE IN HUMAN CERVICAL CANCER CELLS
    Autorzy:
    Zhang, Qijiayu
    Sun, Yi
    Huang, Yuxi
    Sun, Jing
    Zhao, Chongbo
    Song, Yijun
    Wu, Juanhua
    Powiązania:
    https://bibliotekanauki.pl/articles/895719.pdf
    Data publikacji:
    2019-12-29
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Tematy:
    apoptosis
    cervical cancer
    Matrine
    berberine
    Opis:
    Cervical cancer is the fourth leading cause of malignancy-related mortality in women worldwide, and effective advanced-stage therapies are urgently required. Berberine is a quaternary ammonium compound extracted from traditional Chinese medicinal herbs, including Phellodendron spp., with antibacterial and antitumor activities. Matrine, the main active ingredient of Sophora flavescens rhizomes, has not only traditionally described health effects but is also widely used for its anticancer, anti-inflammatory, immunoregulatory, antiviral, and hepatoprotective effects. We investigated the antitumor activities of berberine and matrine against human cervical cancer HeLa and SiHa cells using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, along with flow cytometry and western blotting analyses, to assess the effect of the compounds on the cellular status and apoptosis- and cell cycle-related proteins. The 24 h half-maximal inhibitory concentrations (IC50) of berberine and matrine were 123.633 ± 4.278 µmol/L and 9.625 ± 0.245 mmol/L against HeLa cells and 105.067 ± 3.745 µmol/L and 8.50 ± 0.23 mmol/L against SiHa cells, respectively. Berberine plus matrine inhibited cancer cell growth and caused cell cycle arrest. We observed an increased stimulation of apoptosis, which was likely mediated by enhanced levels of caspase-3, caspase-9, and B-cell lymphoma 2 (Bcl-2)-associated X protein (Bax), as well as decreased Bcl-2 protein expression. Cell cycle arrest in the G1 phase was probably mediated by p21 upregulation and cyclin-dependent kinase (Cdk)-4, Cdk-6, and cyclin D1 suppression. Combination treatment with berberine and matrine effectively inhibited human cervical cancer cell proliferation, most likely by stimulating apoptosis and inducing cell cycle arrest.
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 6; 1089-1097
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Study of the Effect of DINA on the Polymorphic Transition of ε-CL-20 in Composite Modified Double Base Propellants
    Autorzy:
    Wu, Zongkai
    Zheng, Wei
    Pei, Jiangfeng
    Chen, Zhiqun
    Zhang, Jun
    Song, Xiuduo
    Wang, Jiangning
    Zhang, Dongxiang
    Zhao, Fengqi
    Powiązania:
    https://bibliotekanauki.pl/articles/27788019.pdf
    Data publikacji:
    2021
    Wydawca:
    Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego
    Tematy:
    CMDB propellant
    CL-20
    DINA
    polymorphic transition
    Opis:
    Abstract: The polymorphic transition of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazatetracyclo[5.5.0.05,9.03,11]dodecane (CL-20) is influenced by the materials and conditions used in the preparation of propellants, and limits the application of ε-CL-20 in solid propellants. In the present work, the effect of dinitroxydiethylnitramine (DINA) on the polymorphic transition of ε-CL-20 in CMDB propellants was investigated by Raman spectroscopy and the Calvet microcalorimeter method. The performance of propellants with CL-20 as affected by DINA was studied by the theoretical prediction of their energetic parameters, stability, combustion, and mechanical tests, respectively. The results showed that the polymorphic transition temperature of ε-CL-20 to α-CL-20 can be reduced to 75 °C by DINA. Expansion of the crystal volume during the process of the ε-CL-20 to α-CL-20 transition will produce obvious cracks in the surface of the crystals. NC/NG can inhibit the effect of DINA on the polymorphic transition of ε-CL-20. The theoretically predicted results indicated that adding DINA will not lower the energy level of CMDB propellants containing CL-20. The DSC and VST results showed that CL-20 has good compatibility and thermal stability with DINA. The burning rate tests revealed that adding DINA decreases the burning rates of CMDB propellants containing CL-20. Mechanical property testing showed that adding DINA can clearly improve the mechanical properties of CMDB propellants containing CL-20. The results of these investigations suggested that DINA has no effect on the crystalline stability of ε-CL-20 in the solventless extrusion process, which contributes to a significant understanding of practical applications and provides guidance for applied research on the use of CL-20 in propellants.
    Źródło:
    Central European Journal of Energetic Materials; 2021, 18, 2; 165--182
    1733-7178
    Pojawia się w:
    Central European Journal of Energetic Materials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Fatigue life prediction for Ni-based superalloy GH4169 considering machined surface roughness and residual stress effects
    Autorzy:
    Wu, Z. R.
    Wang, S. Q.
    Yang, X.
    Pan, L.
    Song, Y. D.
    Powiązania:
    https://bibliotekanauki.pl/articles/1839712.pdf
    Data publikacji:
    2021
    Wydawca:
    Polskie Towarzystwo Mechaniki Teoretycznej i Stosowanej
    Tematy:
    surface roughness
    residual stress
    fatigue crack
    life prediction
    GH4169
    Opis:
    Establishing a fatigue life prediction model considering the machined surface state is of great significance to improve fatigue life prediction accuracy. Fatigue tests with different machined surface states of GH4169 alloy were conducted firstly. The influence of surface state parameters on the fatigue life was analyzed. Then, the machined surface stress concentration factor and residual stress were introduced into the fatigue crack initiation and propagation models. Finally, the fatigue life prediction model of GH4169 material considering the surface states was established. The prediction results based on the proposed model are almost within a factor of two scatter band of the test results.
    Źródło:
    Journal of Theoretical and Applied Mechanics; 2021, 59, 2; 215-226
    1429-2955
    Pojawia się w:
    Journal of Theoretical and Applied Mechanics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    A counterexample in comonotone approximation in $L^p$ space
    Autorzy:
    Wu, Xiang
    Zhou, Song
    Powiązania:
    https://bibliotekanauki.pl/articles/1396162.pdf
    Data publikacji:
    1993
    Wydawca:
    Polska Akademia Nauk. Instytut Matematyczny PAN
    Opis:
    Refining the idea used in [24] and employing very careful computation, the present paper shows that for 0 < p ≤ ∞ and k ≥ 1, there exists a function $f ∈ C_{[-1,1]}^k$, with $f^{(k)}(x)≥ 0$ for x ∈ [0,1] and $f^{(k)}(x) ≤ 0$ for x ∈ [-1,0], such that lim sup_{n→∞} (e_n^{(k)}(f)_p) / (ω_{k+2+[1/p]}(f,n^{-1})_{p}) = + ∞ where $e_n^{(k)}(f)_p$ is the best approximation of degree n to f in $L^p$ by polynomials which are comonotone with f, that is, polynomials P so that $P^{(k)}(x)f^{(k)}(x) ≥ 0$ for all x ∈ [-1,1]. This theorem, which is a particular case of a more general one, gives a complete solution to the converse result in comonotone approximation in $L^p$ space for 1 < p ≤ ∞.
    Źródło:
    Colloquium Mathematicum; 1993, 64, 2; 265-274
    0010-1354
    Pojawia się w:
    Colloquium Mathematicum
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Increasing nitrogen use efficiency with lower nitrogen application frequencies using zeolite in rice paddy fields
    Autorzy:
    Wu, Q.
    Chen, T.
    Chi, D.
    Xia, G.
    Sun, Y.
    Song, Y.
    Powiązania:
    https://bibliotekanauki.pl/articles/2082479.pdf
    Data publikacji:
    2019
    Wydawca:
    Polska Akademia Nauk. Instytut Agrofizyki PAN
    Tematy:
    available nitrogen
    nitrogen uptake
    root system
    labour force
    Opis:
    Zeolite can effectively regulate the nutrient status in the root zone of crops, thereby increasing nitrogen utilization. However, there has been relatively little research conducted concerning a possible reduction in the frequency of nitrogen application due to the sustained-release properties of zeolite. In this study, 157.5 kg ha-1 nitrogen in the form of urea fertilizer was applied at the same rate, either as a one-time application or as a 3-way split application with and without 10 t ha-1 zeolite. The effects on rice yield, nitrogen uptake, root morphology and soil properties were evaluated in 2014 and 2015. Results showed that zeolite could enhance the biomass, leaf area index and nitrogen uptake. A higher rice grain yield and nitrogen uptake following soil treatment with zeolite could be attributed to a higher soil cation exchange capacity as well as nitrogen and potassium availability in the soil especially during the vegetative period of the rice plant. The addition of nitrogen to the soil as a one-time application or 3-way split application with 10 t ha-1 zeolite significantly increased rice grain yield by 8.5 or 10.7% compared with nitrogen as a one-time application without zeolite. Zeolite addition greatly improved the development of root morphology and activity compared with treatments without zeolite, which contributed to additional plant growth. The addition of nitrogen to the soil with 10 t ha-1 zeolite as a one-time application that can significantly increase nutrient retention is recommended to improve rice grain yield and decrease nitrogen application frequencies in order to lower both labour forces and energy requirements.
    Źródło:
    International Agrophysics; 2019, 33, 2; 263-269
    0236-8722
    Pojawia się w:
    International Agrophysics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Simultaneous state and parameter estimation based actuator fault detection and diagnosis for an unmanned helicopter
    Autorzy:
    Wu, C.
    Qi, J.
    Song, D.
    Qi, X.
    Han, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/329847.pdf
    Data publikacji:
    2015
    Wydawca:
    Uniwersytet Zielonogórski. Oficyna Wydawnicza
    Tematy:
    actuator fault detection
    actuator fault diagnosis
    unmanned helicopter
    Kalman filter
    set membership filter
    adaptive scheme
    detekcja uszkodzeń
    diagnostyka uszkodzeń
    śmigłowiec bezzałogowy
    filtr Kalmana
    Opis:
    Simultaneous state and parameter estimation based actuator fault detection and diagnosis (FDD) for single-rotor unmanned helicopters (UHs) is investigated in this paper. A literature review of actuator FDD for UHs is given firstly. Based on actuator healthy coefficients (AHCs), which are introduced to represent actuator faults, a combined dynamic model is established with the augmented state containing both the flight state and AHCs. Then the actuator fault detection and diagnosis problem is transformed into a general nonlinear estimation one: given control inputs and the measured flight state contaminated by measurement noises, estimate both the flight state and AHCs recursively in each time-step, which is also known as the simultaneous state and parameter estimation problem. The estimated AHCs can further be used for fault tolerant control (FTC). Based on the existing widely used nonlinear estimation methods such as the unscented Kalman filter (UKF) and the extended set-membership filter (ESMF), three kinds of adaptive schemes (KF-UKF, MIT-UKF and MIT-ESMF) are proposed by our team to improve the actuator FDD performance. A comprehensive comparative study on these different estimation methods is given in detail to illustrate their advantages and disadvantages when applied to unmanned helicopter actuator FDD.
    Źródło:
    International Journal of Applied Mathematics and Computer Science; 2015, 25, 1; 175-187
    1641-876X
    2083-8492
    Pojawia się w:
    International Journal of Applied Mathematics and Computer Science
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Analysis of the cracking mechanisms in pre-cracked sandstone under radial compression by moment tensor analysis of acoustic emissions
    Autorzy:
    Wang, Guozhu
    Luo, Xulin
    Song, Lei
    Wang, Yu
    Han, Mouwang
    Song, Zhaocun
    Wu, Linjun
    Wang, Zukun
    Powiązania:
    https://bibliotekanauki.pl/articles/2174031.pdf
    Data publikacji:
    2022
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    emisja akustyczna
    mechanizm pękania
    tensor momentu
    piaskowiec wstępnie spękany
    kompresja promieniowa
    acoustic emission
    cracking mechanism
    moment tensor
    pre-cracked sandstone
    radial compression
    Opis:
    Rock masses, especially those with different pre-existing cracks, are prone to instability and failure under tensile loading, resulting in different degrees of engineering disasters. Therefore, to better understand the effect of pre-existing cracks with different dip angles on the tensile instability failure behaviour of rocks, the mechanism of crack initiation, propagation and coalescence in precracked sandstone under radial compression loading is investigated through numerical simulations. The temporal and spatial evolution of acoustic emission (AE) events is investigated by the moment tensor (MT), and the fracture mode of micro-cracks is determined. The results show that the pre-existing cracks weaken the specimens. The strength, crack initiation points and macro-failure modes of the specimens differ significantly depending on the dip angle of the pre-existing crack. For different dip angles of the pre-existing cracks, all the micro-cracks at the crack initiation point are tensile cracks, which are dominant during the whole loading process, and mixed cracks are mainly generated near the upper and lower loading ends after the peak stress. Of the total number of events, more than 75% are tensile cracks; approximately 15% are shear mode cracks; and the remainder consist of mixed mode cracks. The study reveals the instability and failure mechanism of pre-cracked rock, which is of great significance to ensure the long-term stability of rock mass engineering.
    Źródło:
    Archives of Civil Engineering; 2022, 68, 3; 447--468
    1230-2945
    Pojawia się w:
    Archives of Civil Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Variation of strata pressure and axial bolt load at a coal mine face under the effect of a fault
    Zmienność ciśnienia górotworu i obciążenia osiowe działające na segmenty obudowy w rejonie przodka spowodowane obecnością uskoków
    Autorzy:
    Shi, Hao
    Zhang, Houquan
    Song, Lei
    Wu, Yu
    Powiązania:
    https://bibliotekanauki.pl/articles/218749.pdf
    Data publikacji:
    2019
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    symulacje numeryczne FLAC 3D
    naprężenia osiowe działające na obudowę
    zachowanie górotworu
    górnictwo
    efekt uskoku
    model odprężania
    FLAC3D numerical simulation
    axial bolt load
    strata behavior
    mining and fault effect
    strain-softening model
    Opis:
    The cohesion and internal friction angle were characterized as quadratic functions of strain and were assumed to follow the Mohr-Coulomb criterion after the yield of peak strength. These mechanical parameters and their variations in post-peak softening stage can be exactly ascertained through the si-multaneous solution based on the data points of stress-strain curves of triaxial compression tests. Taking the influence of the fault into account, the variation of strata pressure and roadway convergence with coal advancement, the temporal and spatial distribution of axial bolt load were numerically simulated by FLAC3D (Fast Lagrangian Analysis of Continua) using the ascertained post-peak mechanical parameters according to the cohesion weakening and friction strengthening model. The change mechanism of axial load of single rock bolt as abutment pressure changes was analyzed, through the comparison analysis with the results of axial bolt load by field measurements at a coal mine face. The research results show that the simulated results such as the period of main roof weighting, temporal and spatial distribution of axial bolt load are in accordance with field measurement results, so the validity of the numerical model is testified. In front of the working face, the front abutment pressure increases first and then decreases, finally tends to be stable. A corresponding correlation exists between the variation of axial bolt load and rock deformation along the bolt body. When encountered by a fault, the maximum abutment pressure, the influential range of mining disturbance and the roadway convergence between roof and floor before the working face are all increased. In the roadways along the gob, axial bolt loads on the side of the working face decrease, while the other side one increases after the collapse of the roof. As superficial surrounding rock mass is damaged, the anchoring force of rock bolts will transfer to inner rock mass for balancing the tensile load of the bolts.
    Zwięzłość skał oraz kąt tarcia wewnętrznego zdefiniowano jako kwadratowe funkcje naprężenia, następnie przyjęto że ich rozkład po osiągnięciu naprężenia granicznego opisany jest wzorem Mohra-Coulomba. Wymienione parametry mechaniczne i ich zmienność po osiągnięciu naprężenia granicznego obliczyć można dokładnie poprzez jednoczesne rozwiązanie oparte o analizę punktów na krzywej wykresu rozciągania uzyskanych w testach ściskania trójosiowego. Uwzględniając wpływ obecności uskoku, zmienność ciśnienia w górotworze i konwergencji chodnika wraz z postępem przodka, rozkłady naprę-żeń i obciążeń działających na segmenty obudowy i ich zmienność w czasie i przestrzeni modelowano w oparciu o pakiet FLAC3D (Fast Lagrangian Analysis of Continua), wykorzystując uprzednio obliczone wielkości parametrów mechanicznych dla stanu po osiągnięciu naprężenia granicznego, zgodnie z mo-delem słabnącej zwięzłości i wzmocnionego tarcia. Mechanizm zmiany naprężeń osiowych działających na pojedynczy segment obudowy analizowano w odniesieniu do ciśnienia warstw sąsiadujących, poprzez analizę porównawczą wyników pomiarów obciążeń segmentów obudowy w rejonie przodka. Wykazano, że wyniki symulacji: okresy obciążenia stropu, rozkłady naprężeń i obciążeń działających na elementy obudowy i ich zmienność w czasie i przestrzeni zgodne są z wynikami pomiarów w miejscu, w ten sposób potwierdzając wiarygodność modelu numerycznego. W rejonie przodka ciśnienie warstw sąsiadujących w górotworze najpierw rośnie, następnie maleje, a w końcu stabilizuje się. Istnieje odpowiednia korelacja pomiędzy zmiennością rozkładu naprężeń i obciążeń działających na elementy obudowy a odkształceniem warstw skalnym wzdłuż konstrukcji obudowy. W przypadku wystąpienia uskoku, występuje maksymalne ciśnienie warstw otaczających- poważny czynnik powodujący wszelkiego rodzaju zaburzenia a także nasilenie konwergencji chodnika pomiędzy stropem a podłożem w rejonie przed przodkiem. W chodnikach wzdłuż zrobów, obciążenia osiowe obudowy działające z jednej strony maleją, po drugiej zaś stronie rejonu przodkowego rosną po zawale stropu. Płytka warstwa otaczającego górotworu ulega zniszczeniu, siła podtrzymująca obudowę przeniesiona zostanie wewnątrz górotworu, tak by zrównoważyć naprężenia rozciągające działające na obudowę.
    Źródło:
    Archives of Mining Sciences; 2019, 64, 2; 351-374
    0860-7001
    Pojawia się w:
    Archives of Mining Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    CAMPTOTHECIN INHIBITS MIGRATION, INVASION AND CLONOGENIC PROPERTY OF LIVER CANCER CELLS BY MODULATING MICRORNA EXPRESSION
    Autorzy:
    Liu, Zhenzhong
    Wu, Song
    Li, Xiaoqian
    Powiązania:
    https://bibliotekanauki.pl/articles/895460.pdf
    Data publikacji:
    2020-04-29
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Tematy:
    Hepatocellular Carcinoma
    cell proliferation
    cell cycle
    Camptothecin
    miRNA
    Opis:
    Camptothecin (CPT), an alkaloid natural product, extracted from Camptotheca acuminata bark, has been reported to have potential antitumor activity in diverse cancers. MicroRNAs (MiRNAs) are a class of short, non-coding RNAs that plays a crucial role in the normal physiology by attenuating translation. Here, we showed that the CPT modulates the expression of miRNAs in hepatocellular carcinoma cells (HCC). Microarray analysis reveals that CPT modulates the expression of as many as 39 miRNAs in HCC cells (Huh7), 27 miRNAs were downregulated whereas 12 miRNAs were upregulated. miR-16 is the key miRNA upregulated by CPT and targets key prosurvival proteins (MMP-2, MMP-9 and cyclin D1). Our results demonstrate that CPT is inhibiting cell viability of HCC cells significantly when compared with the untreated cells. Wound healing and colony formation assay confirm inhibition of cell migration and clonogenic property of Huh7 cells respectively, upon the dose-dependent treatment of CPT. Furthermore, the Boyden chamber assay analysis revealed a significant inhibition of number of invasive cells in CPT treated cells with comparison to untreated Huh7 cells. Mechanistically, CPT upregulates miR-16 expression which targets MMP-2, MMP-9, cyclin D1 downregulation and subsequently upregulates the expression of E-cadherin, TIMP1, p21, and p27, thereby inhibits cell migration, invasion and clonogenic property of HCC cells. In summary, CPT treatment in Huh7 cells decreases cell viability and upregulates miR-16 expression, which results in inhibition of cell migration, invasion and clonogenic property of cells, by decreasing MMP-2, MMP-9, cyclin D1 and increasing the expression of cell cycle-regulated proteins p21 and p27.
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2020, 77, 2; 295-304
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Demonstration of a new indicator for studying upwelling in the Northern South China Sea
    Autorzy:
    Lin, L.
    Wang, Y.-S.
    Sun, C.-C.
    Li, N.
    Wang, H.
    Mitchell, B.G.
    Wu, M.-L.
    Song, H.
    Wu, J.-F.
    Powiązania:
    https://bibliotekanauki.pl/articles/48889.pdf
    Data publikacji:
    2011
    Wydawca:
    Polska Akademia Nauk. Instytut Oceanologii PAN
    Tematy:
    China Sea
    cluster analysis
    multivariate statistical analysis
    principal component analysis
    remote sensing
    satellite monitoring
    sea surface temperature
    silicate
    spatial distribution
    upwelling
    Opis:
    In order to demonstrate that silicate (SiO3-Si) can be used as an indicator to study upwelling in the northern South China Sea, hierarchical cluster analysis (CA) and principle component analysis (PCA) were applied to analyse the metrics of the data consisting of 14 physical-chemical-biological parameters at 32 stations. CA categorized the 32 stations into two groups (low and high nutrient groups). PCA was applied to identify five Principal Components (PCs) explaining 78.65% of the total variance of the original data. PCA found important factors that can describe nutrient sources in estuarine, upwelling, and non-upwelling areas. PC4, representing the upwelling source, is strongly correlated to SiO3-Si. The spatial distribution of silicate from the surface to 200 m depth clearly showed the upwelling regions, which is also supported by satellite observations of sea surface temperature.
    Źródło:
    Oceanologia; 2011, 53, 2
    0078-3234
    Pojawia się w:
    Oceanologia
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    An association between cumulative exposure to light at night and the prevalence of hyperuricemia in steel workers
    Autorzy:
    Li, Xiaoming
    Xu, Xianghui
    Song, Yang
    Cui, Shiyue
    Xue, Chao
    Wang, Lihua
    Wu, Jianhui
    Yuan, Juxiang
    Powiązania:
    https://bibliotekanauki.pl/articles/2085783.pdf
    Data publikacji:
    2021-06-28
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    uric acid
    circadian rhythms
    hyperuricemia
    steel workers
    light at night
    restricted cubic spline
    Opis:
    ObjectivesExposure to light at night (LAN) can disturb circadian endocrine and metabolic rhythms. Hyperuricemia (HUA) is an early-onset metabolic disorder. However, it is still not clear whether LAN exposure increases the prevalence of HUA.Material and MethodsThe authors used crosssectional data on the Beijing-Tianjin-Hebei occupational populations cohort from March–July 2017. A total of 7664 steel workers were finally selected to investigate the relationship between LAN exposure and the prevalence of HUA among steel workers. The authors collected demographic and socio-economic data, as well as information on lifestyle factors, anthropometric measures, and laboratory tests. The restricted cubic spline method was used to analyze the dose-response relationship between cumulative LAN exposure and the prevalence of HUA. Logistic regression analyses were used to fit the relationship between them.ResultsThe average age of the participants was 43.5±8.6 years; 7051 (91.7%) of them were males, 2749 (35.9%) reported to suffer from HUA, and 1241 (16.2%) were not exposed to LAN. There was a significant non-linear dose-response relationship between them. After adjustment for the confounding factors, including demographic data, lifestyle factors, etc., the lower LAN exposure was significantly associated with HUA (0–1931.7 days, OR = 1.180, and the 95% CI: 1.000–1.394; 1931.7–4343 days, OR = 1.215, 95% CI: 1.035–1.426).ConclusionsThis study revealed that a certain amount of exposure to LAN is independently related to the prevalence of HUA in steel workers in China.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2021, 34, 3; 385-401
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Investigations on the Anisotropic g Factors of the $Ni^{3+}$ Site in $La_2Ni_{0.5}Li_{0.5}O_4$
    Autorzy:
    Kuang, M.
    Wu, S.
    Zhang, Z.
    Song, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/1400149.pdf
    Data publikacji:
    2013-04
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    76.30.Fc
    71.70.Ch
    75.10.Dg
    Opis:
    The anisotropic g factors $g_{∥}$ and $g_{⊥}$ of $La_2Ni_{0.5}Li_{0.5}O_4$ are theoretically investigated using the perturbation formulae of the g factors for a low spin $(S=1//2) 3d^7$ ion in tetragonally elongated octahedra. The studied $Ni^{3+} (3d^7)$ center arises from the original $Ni^{2+}$ capturing one hole by $Li^{+}$ doping. The positive anisotropy $\Delta g (= g_{⊥}-g_{∥})$ can be ascribed to the lowest $\text{}^2 A_{1g}$ state due to the obvious (about 0.14 Å) tetragonal elongation of the oxygen octahedron around the $Ni^{3+}$ site via the Jahn-Teller effect, and the effective magnetic moment is also interpreted in a uniform way. The calculated results show good agreement with the experimental data, and the imperfection of the previous studies based on various adjusted tetragonal energy splittings without correlating to the local structure of the magnetic center is thus overcome in this work.
    Źródło:
    Acta Physica Polonica A; 2013, 123, 4; 734-736
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Order unicyclic graphs according to spectral radius of unoriented laplacian matrix
    Autorzy:
    Fan, Yi-Zheng
    Wu, Song
    Powiązania:
    https://bibliotekanauki.pl/articles/743077.pdf
    Data publikacji:
    2008
    Wydawca:
    Uniwersytet Zielonogórski. Wydział Matematyki, Informatyki i Ekonometrii
    Tematy:
    unicyclic graph
    Laplacian matrix
    spectral radius
    Opis:
    The spectral radius of a graph is defined by that of its unoriented Laplacian matrix. In this paper, we determine the unicyclic graphs respectively with the third and the fourth largest spectral radius among all unicyclic graphs of given order.
    Źródło:
    Discussiones Mathematicae Graph Theory; 2008, 28, 3; 487-499
    2083-5892
    Pojawia się w:
    Discussiones Mathematicae Graph Theory
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Experimental study on the effects of vibrational frequency on the permeability of gas-containing coal rocks
    Autorzy:
    Bairu, Zhu
    Yang, Song
    Beining, Wu
    Yongqi, Li
    Powiązania:
    https://bibliotekanauki.pl/articles/1853881.pdf
    Data publikacji:
    2021
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    wibracje
    przepuszczalność
    ciśnienie gazu
    gas-containing coal rock
    low-frequency vibration
    gas pressure
    permeability
    sensitivity coefficient
    Opis:
    Low-frequency mechanical vibrations can trigger disasters such as coal-gas outbursts. An in-house “vibration-triaxial stress-seepage” experimental apparatus was used to measure the gas flow rate of rock specimens with varying vibrational frequency, gas pressure, and confining pressure. The results of these tests were then used to derive expressions that describe how the permeability of gas-containing coal rocks is related to these aforementioned factors. In addition, sensitivity coefficients were defined to characterise the magnitude of the permeability response to each permeability-affecting factor (i.e., vibrational frequency and gas pressure). The following insights were gained, regarding the effects of vibrational frequency on the permeability of gas-containing coal rocks: (1) If gas pressure and confining pressure are fixed, the permeability of gas-containing coal rocks rapidly increases, before gradually decreasing, with increasing vibrational frequency. Thus, the permeability of the gas-containing coal rock is always larger with vibrations than without. (2) If vibrational pressure and confining pressure are fixed, the relationship between the permeability of gas-containing coal rocks and gas pressure is consistent with the “Klinkenberg effect,” i.e., the permeability initially decreases, and then increases, with increasing gas pressure. (3) The change in permeability induced by each unit change in gas pressure is proportional to the gas pressure sensitivity coefficient. (4) The change in permeability induced by each unit change in vibrational frequency is proportional to the vibrational frequency sensitivity coefficient.
    Źródło:
    Archives of Mining Sciences; 2021, 66, 2; 265-278
    0860-7001
    Pojawia się w:
    Archives of Mining Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
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