Autor: Sharma, Vinay S. - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Synthesis and in vitro antimicrobial evaluation of some new chalcones containing vinyl ester group and substituted alkyl chain
Autorzy:: Sharma, Vinay S.
Patel, R. B.
Powiązania:: https://bibliotekanauki.pl/articles/1191249.pdf
Data publikacji:: 2016
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:: Antibacterial
Antifungal
Chalcone
Vinyl ester
Opis:: A novel series of chalconyl vinyl ester based derivatives were designed and synthesized. The newly synthesized compounds were studied for efficacy against several bacteria (E.Coli, P.Aeruginosa, S.Aureus, S.Pyogenus) and fungi (C.Albicans, A.Niger, Clavatus) using the broth dilution technique. Chalcones were prepared by treatment of 4-iodo acetophenone with 4-hydroxy benzaldehyde by Claisen-Schimidt condensation reaction. Various chalconyl vinyl ester derivatives (C1-C8) were prepared by reaction of chalcone with 4-n-alkoxy cinnamic acids derivatives. Compound C8 shows the best bioactive desired antibacterial analogue with less MIC value against different tested strains. All the final synthesized compounds were characterized by IR, 1H NMR, and elemental analysis.
Źródło:: World Scientific News; 2016, 54; 240-251
2392-2192
Pojawia się w:: World Scientific News
Dostawca treści:: Biblioteka Nauki

Artykuł

Skocz do pozycji: 2.

Tytuł:: Synthesis, biological investigations, QSAR and DFT analysis of sulfonamide chalcones as potential: antimicrobial, antifungal and antimalarial agents
Autorzy:: Meena, Lakshman R.
Sharma, Vinay S.
Swarnkar, Pawan
Powiązania:: https://bibliotekanauki.pl/articles/1031835.pdf
Data publikacji:: 2020
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:: Claisen-Schmidt condensation
antifungal
antimalarial
antimicrobial
sulfonamide hybrids
α-β-unsaturated ketone
Opis:: Various aromatic aldehydes condense with aryl ketone (N-(4-(phenylsulfonamido)phenyl) acetamide) in presence of aqueous alkaline NaOH to form α, β-unsaturated ketone (N-(4-(N-phenylsulfamoyl)phenyl)cinnamamide derivatives or sulfonamide chalcone derivatives). We were synthesized novel sulfonamides chalcones synthesized through Claisen-Schmidt condensation of aromatic aldehydes and sulfonamide containing acetanilide. All the synthesized compounds were characterized using Mass, FTIR, NMR (1H & 13C) spectra analysis. The synthesized sulfonamide chalcone hybrids were screened antimicrobial activity, antifungal and antimalarial activity.
Źródło:: World Scientific News; 2020, 147; 179-196
2392-2192
Pojawia się w:: World Scientific News
Dostawca treści:: Biblioteka Nauki

Artykuł

Skocz do pozycji: 3.

Tytuł:: Synthesis and biological activity of novel sulfonamides derivatives of various heterocyclic compounds
Autorzy:: Meena, Lakshman R.
Sharma, Vinay S.
Swarnkar, Pawan
Powiązania:: https://bibliotekanauki.pl/articles/1031472.pdf
Data publikacji:: 2020
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:: 4-dichlorobenzoic acid
Sulfonamide
anti-fungal
anti-malarial
anti-microbial
Opis:: A novel series of Sulfonamide embedded heterocyclic derivatives were synthesized and well characterized by using 1H NMR, 13C NMR and IR spectroscopic techniques. All the new synthesized compounds were evaluated to their anti-bacterial, anti-fungal and anti- malarial activities. Noticeably, compound 5b was the most potent compound in vitro anti-microbial (S. aureus) with a MTCC value of 96 microgram/ml and compounds 5g and 5j showed most potent activity in vitro anti-fungal (C. albicans) with a MTCC value of 277microgram/ml. Similarly, compound 5e showed high potent activity of anti-malarial (P. falciparum) with mean IC50 value as compared to other synthesized derivatives.
Źródło:: World Scientific News; 2020, 142; 120-134
2392-2192
Pojawia się w:: World Scientific News
Dostawca treści:: Biblioteka Nauki

Artykuł

Skocz do pozycji: 4.

Tytuł:: Synthesis and antimicrobial activity of oxadiazole nucleus containing 2,5-substituted 1,3,4-oxadiazole derivatives
Autorzy:: Gajera, Jayesh L
Sutariya, Jignesh K.
Rakesh Gothwal, Rakesh
Sharma, Vinay S.
Ram, Haresh
Godhaviya, Pankaj K.
Powiązania:: https://bibliotekanauki.pl/articles/1839273.pdf
Data publikacji:: 2021
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:: cyclohexanecarbohydrazide
antibacterial
antifungal
1,3,4-oxadiazole
Opis:: In this study, we report the synthesis of 2,5-substituted 1,3,4-oxadiazole derivatives using condensation of cyclohexanecarbohydrazide derivatives and carbon disulfide. In present study, we have prepared total seven derivatives based on 1,3,4-oxadiazole core further functionalized with thiol moieties. The structures of synthesized compounds (C1-C9) were confirmed by the 1H NMR, and Mass spectrometry. These synthesized molecules were subjected to antibacterial and fungal activity against selected microbial and fungal strains. Some of derivatives showed good biological behaviour against gram positive and gram negative bacteria.
Źródło:: World Scientific News; 2021, 162; 75-86
2392-2192
Pojawia się w:: World Scientific News
Dostawca treści:: Biblioteka Nauki

Artykuł

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