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Wyświetlanie 1-15 z 84
Tytuł:
Cytopathology of canine lymphomas (100 cases)
Autorzy:
Sapierzynski, R.
Micun, J.
Jagielski, D.
Jurka, P.
Powiązania:
https://bibliotekanauki.pl/articles/31296.pdf
Data publikacji:
2010
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
cytopathology
canine lymphoma
lymphoma
dog
malignant lymphoma
tumour
animal disease
occurrence
T cell
biopsy
Opis:
Malignant lymphoma is one of the most common malignant tumours occurring in dogs. Fine needle aspiration biopsy (FNAB) is an excellent, specific diagnostic procedure used to assess pathological processes in lymph nodes. The aim of the present study was to conduct a cytopathological analysis of lymphoma in dogs and to analyse some epidemic aspects of occurrence of lymphoma in 100 dogs using Giemsa stained slides. Samples were obtained by fine needle aspiration biopsy, fine needle non-aspiration biopsy, lymph node impression smears and by examination of body cavity effusions. The determination of the type and subtype of tumour was made on the basis of the updated Kiel classification adopted for dogs. Based on cytopathological analysis, the lymphoma was diagnosed in 100 dogs: 44 were female and 56 male. The animals’ age ranged from 1.5 year to 15 years (median: 7.5 years), the animals were of different breeds (72% of all dogs belonged to 28 different breeds) and crossbreeds (28%). In 29% of dogs the regional or general lymphadenomegaly was the only clinical sign observed, in remaining cases (71%) at least one abnormality connected to lymphoma was found. Among all diagnosed lymphomas, high-grade lymphomas were more prevalent (86% of all cases) than low-grade lymphomas (14% of all cases). The possibility of boxers having a predisposition to T cell lymphoma development could be also suspected.
Źródło:
Polish Journal of Veterinary Sciences; 2010, 13, 4
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Nowotwory gruczołu sutkowego u suk - model badań raka piersi u kobiet
Canine mammary tumors - a model for studying breast cancer in women
Autorzy:
Dolka, I.
Motyl, T.
Malicka, E.
Sapierzynski, R.
Powiązania:
https://bibliotekanauki.pl/articles/859178.pdf
Data publikacji:
2010
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
onkologia
psy
suki
nowotwory gruczolu sutkowego
czlowiek
nowotwory piersi
modele zwierzece
czynniki prognostyczne
markery nowotworowe
markery immunohistochemiczne
Źródło:
Życie Weterynaryjne; 2010, 85, 12
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Practical aspects of immunocytochemistry in canine lymphomas
Autorzy:
Sapierzynski, R.
Powiązania:
https://bibliotekanauki.pl/articles/32144.pdf
Data publikacji:
2010
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
immunocytochemistry
canine lymphoma
lymphoma
dog
cytology
immunophenotype
tumour cell
biopsy
diagnosis
Kiel classification
Lennert classification zob.Kiel classification
Opis:
The aim of this study was to evaluate the utility of immunocytochemistry in a standard veterinary practice and to determine the immunophenotype of tumor cells in cases of multicentric lymphoma in dogs by immunocytochemical analysis of fine-needle biopsy specimens. The study was performed on cytological samples collected from 54 dogs, in which multicentric lymphoma was recognised based on clinical data, cytology or cytology and histology, and follow-up information. Diagnosis of lymphoma was established according to the updated Kiel classification. Immunocytochemical assays were conducted using commercially available antibodies to the pan T-lymphocyte marker CD3 and B cell antigen receptor complex CD79 alpha. Among all animals examined B cell lymphoma was recognized in 42/54 (77.8%) of cases, while in the remaining 12/54 (22.2%) of dogs T cell lymphoma was recognized. In 11 animals with lymphoma recognized cytologically, in which an entire lymph node was obtained for histology, the results of routine cytology and immunocytochemistry fully corresponded with findings revealed by histology and immunohistochemistry. Immunocytochemistry can be successfully conducted in smears stored at room temperature for 24 hours without changes of staining results. It can be stated that application of standard cytopathological assessment in connection with immunocytochemistry of lymph nodes samples collected from dogs with lymphoma is a method of choice for establishing final diagnosis, and avoids the need for reexamination or collection of tissue samples for histopathology and immunohistochemistry during surgical procedures in ambiguous cases.
Źródło:
Polish Journal of Veterinary Sciences; 2010, 13, 4
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The first description of gastric Helicobacter in free-ranging wild boar [Sus scrofa] from Poland
Autorzy:
Fabisiak, M
Sapierzynski, R.
Salamaszynska-Guz, A.
Kizerwetter-Swida, M.
Powiązania:
https://bibliotekanauki.pl/articles/32325.pdf
Data publikacji:
2010
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
boar
wild animal
gastric mucosa
Sus scrofa
Polska
hunting season
Helicobacter
histopathology
polymerase chain reaction
Helicobacter pylori
animal species
animal infection
Opis:
Specimens of gastric mucosa of 17 free-ranging wild boars (Sus scrofa) shot in the Central Poland during 2007/2008 hunting season were investigated for the presence of Helicobacter species. Histopathology, Helicobacter genus-specific 16S rRNA PCR, and DNA sequence analysis were employed. In PCR analysis the presence of Helicobacter's DNA was detected in one stomach. Obtained sequence analysis showed its relatedness to Helicobacter heilmannii type 2. In histopathology of the PCR-positive sample the presence of tightly coiled spiral bacteria was detected on the surface of the antral mucosa, in gastric pits and lumen of the upper parts of antral glands. Potential pathologic significance of the presence of Helicobacter in the stomach of free-ranging wild boars was obscured by the parasitic invasion-caused gastritis, and remains unknown.
Źródło:
Polish Journal of Veterinary Sciences; 2010, 13, 1; 171-174
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Relationship between receptors for insulin-like growth factor - I, steroid hormones and apoptosis-associated proteins in canine mammary tumors
Autorzy:
Dolka, I.
Motyl, T.
Malicka, E.
Sapierzynski, R.
Fabisiak, M.
Powiązania:
https://bibliotekanauki.pl/articles/32455.pdf
Data publikacji:
2011
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
relationship
receptor
insulin-like growth factor
steroid hormone
apoptosis-associated protein
dog
mammary tumour
cancer
Opis:
In the veterinary literature there are few data concerning the expression of insulin-like growth factor type I (IGF-IR) in the canine mammary gland tumors. The aim of the present study was the evaluation of IGF-IR expression and its correlation to the expression of estrogen receptor α (ERα) and progesterone receptor (PR), proteins: Bcl-2, Bax, p53 in canine mammary gland tumors, and also a correlation with other features: bitch’s age, tumor diameter, histologic type of tumor, degree of histologic malignancy, proliferate activity. The study was done on 112 epithelial neoplasms: 21 (19%) were adenoma, 38 (34%) complex carcinoma (adenocarcinoma), 47 (42%) simple carcinoma (adenocarcinoma) and 6 (5%) solid carcinoma. Histochemistry and immunohistochemistry methods were employed. It was shown that more common and/or higher IGF-IR expression in cells of canine mammary gland tumors was related to the histologic type of cancer of worse prognostic (solid and simple carcinoma), high histologic degree of malignancy (IIIo) but the statistical analysis did not reveal any significant differences. We observed the high degree of IGF-IR expression in tumors which displayed the high ERα and PR expression. These results suggest the involvement of IGF-IR in the development of hormonosensitive canine mammary tumors. Additionally, the significant positive correlation between expression of IGF-IR and p53, Bax was found. Our study provides some evidence that interactions exist between the IGF-IR and these apoptosis-associated proteins may contribute to the development and progression of canine mammary gland tumors. These results require further investigations.
Źródło:
Polish Journal of Veterinary Sciences; 2011, 14, 2
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cytopathological diagnosis of visceral histiocytic sarcoma in five dogs
Autorzy:
Sapierzynski, R.
Jagielski, D.
Dolka, I.
Fabisiak, M.
Powiązania:
https://bibliotekanauki.pl/articles/30621.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
Histiocytic sarcoma is a malignant neoplastic proliferation of atypical histiocytes with tendency to spread, characterized by fast progression to disseminated form - disseminated histiocytic sarcoma. Cytopathology is a low, invasive, cheap, and quick method of diagnosis commonly used in veterinary oncology. The aim of the presented study was description of cases of visceral histiocytic sarcomas in dogs diagnosed by cytopathology and immunocytochemistry. The study was conducted on 5 dogs which were brought to the veterinary clinic because of unspecific clinical signs and tumoral masses recognized in the thoracic or abdominal cavity. Samples of cells were collected during ultrasonography- assisted fine-needle aspiration biopsy (FNAB), smears were stained with Giemsa method and immunocytochemistry (CD3, CD79α, cytokeratin, vimentin, desmin) was also performed in all patients. Four of five dogs were Bernese mountain dogs, nonspecific clinical signs of systemic disease were present in all cases. Visceral mass or masses were detected by ultrasonography or radiography. Final diagnosis of histiocytic sarcoma was obtained on the basis of routine cytopathological examination and confirmed by immunocytochemistry. On the basis the results obtained it can be stated that in cases of typical clinical and cytopathologic pictures, examination of cellular samples collected during ultrasonography-assisted fine-needle biopsy supported by some immunocytopathological characteristics seems to be sufficient method of diagnosis of histiocytic sarcoma in dogs. Visceral histiocytic sarcoma should be included into differential diagnosis in every Bernese mountain dog with nonspecific clinical signs, ambiguous results of hematologic examination and when tumoral mass or masses within a body cavity were detected in imaging techniques.
Źródło:
Polish Journal of Veterinary Sciences; 2012, 15, 4
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
High agreement of routine cytopathology and immunocytochemistry in canine lymphomas
Autorzy:
Sapierzynski, R.
Dolka, I.
Fabisiak, M.
Powiązania:
https://bibliotekanauki.pl/articles/32447.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
The aim of this study was to compare the concordance of immunophenotype established with routine cytopathology (slides stained with Giemsa solution) and immunocytochemistry according to CD3 and CD79 alpha immunoreactivity. The study was performed on cytological samples of 70 canine lymphomas subtyped on the basis of the updated Kiel classification system. Additionally, cytologic samples were examined immunocytochemically for the CD3 and CD79 alpha antigens presence and thus immunophenotype of neoplastic growth was confirmed. The cytopathological and immunocytochemical diagnoses were then compared; in order to measure the concordance between immunocytochemistry (IC) result and Giemsa stain result of the same sample the Cohen's kappa coefficient was calculated. On the basis of the results of immunocytochemistry of 70 cases of canine lymphoma examined 42 were recognized as B cell lymphoma and 28 as T cell lymphoma. Full accordance between the results of routine cytopathology and IC was obtained in 63 out of 70 examined dogs (90% of cases). It can be concluded that cytopathological examination of Giemsa stained smears is helpful in determining the lymphoma cells immunophenotype. Additionally, it seems that combination of routine cytopathology and immunocytochemistry in cases of canine lymphomas allows to obtain the precise diagnosis in 90% of cases, and allows to receive most important information that is necessary for planning of appropriate therapy and to determine prognosis. Finally, this routine procedure allowed to eliminate the need of collection of tissue samples during surgery or core-biopsy and thus time, cost and patient discomfort related to more complex and invasive medical procedures can be easily reduced.
Źródło:
Polish Journal of Veterinary Sciences; 2012, 15, 2
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Histopathology in diagnosis of broiler chicken and layer diseases – review of cases 1999-2010
Autorzy:
Dolka, I.
Sapierzynski, R.
Bielecki, W.
Malicka, E.
Zbikowski, A.
Szeleszczuk, P.
Powiązania:
https://bibliotekanauki.pl/articles/32185.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
The aim of this study was to estimate the prevalence of histopathological lesions in the different organs in relation to the commercial-type and the age of birds (i.e. broiler chickens and layers). During the period 1999-2010 a total of 189 cases was submitted to the Division of Animal Pathomorphology, Department of Pathology and Veterinary Diagnostics at WULS. Most cases were found in broiler chickens (66.7%). The majority of the histopathological lesions were detected in the liver and lymphoid organs. In of 29% cases of hepatic injury pathognomonic lesions associated with inclusion body hepatitis (IBH) were found. The mean age of birds was 23 days. Among IBH cases proventriculitis (58%) was more often found than gizzard lesions (25.8%). Interestingly, we noted some intranuclear inclusions in the epithelial cells within the proventriculus. A low percentage of histopathological evidence of infectious bursal disease (IBD) was reported in chickens. The gastrointestinal tract was the second most frequent predilection site for histopathological lesions. Histopathological findings within the heart and lungs were less common and were more often seen in the upper respiratory tract. Cases of infectious laryngotracheitis (ILT) were registered in broiler chickens (3.2%, mean age 37 days) and in layers (4.8%; mean age 196 days). Lesions associated with Marek’s disease, avian leukosis and fowl pox were recognized only in layers, respectively in 3.2% (mean age 176 days), 1.6% (mean age 205 days) and 1.1% (mean age 196 days) of all cases. Avian encephalomyelitis (AE) was noted only in 0.5% of all cases.
Źródło:
Polish Journal of Veterinary Sciences; 2012, 15, 4
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mismatch between transcriptomic and histopathologic picture of canine lymphomas
Autorzy:
Ostrzeszewicz, M.
Maciejewski, H.
Sapierzynski, R.
Micun, J.
Majewska, A.
Lechowski, R.
Motyl, T.
Jank, M.
Powiązania:
https://bibliotekanauki.pl/articles/32128.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
Lymphoma is one of the most common malignant tumours occurring in dogs. Since there is a constant need for new, more comprehensive laboratory diagnostic tools which permit the precise determination of many tumour-related factors we decided to verify whether the use of microarray analysis could be helpful in classifying lymphomas. The study was performed on samples collected from 7 dogs in which multicentric lymphoma was recognized. Among this group we were able to identify one sub-cluster of transcriptionally similar tumours, which completely differed in terms of the histopathological examination. Among them there were one diffuse large B cell lymphoma, one diffuse macronucleolated medium-sized cell lymphoma and one pleomorphic mixed small and large T-cell lymphoma. The lymphomas belonging to the sub-cluster differed from other analysed tumours in the expression of more than 100 genes of which only 18 were described earlier in regard to lymphomas.
Źródło:
Polish Journal of Veterinary Sciences; 2012, 15, 4
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Nowotwory powiek u psów i kotów
Eyelids neoplasia in dogs and cats
Autorzy:
Sapierzynski, R.
Powiązania:
https://bibliotekanauki.pl/articles/9881.pdf
Data publikacji:
2012
Wydawca:
Okulistyka Weterynaryjna
Tematy:
okulistyka weterynaryjna
psy
koty
choroby oczu
nowotwory powiek
rak plaskonablonkowy rogowaciejacy
melanocytoma
czerniaki
plamy soczewicowe
gruczolaki z gruczolow Meiboma
chloniaki
brodawczaki
objawy chorobowe
diagnostyka
biopsja aspiracyjna cienkoiglowa
badania histopatologiczne
leczenie
Opis:
Physical and functional abnormalities of the lids or adnexal ocular structures may result in abnormalities of the cornea and subsequently vision. Cancer begins when normal cells start to change and grow uncontrollably, forming a mass called a tumor. Eyelid tumors can be either benign or malignant. The most common malignant eyelid tumors include basal cell carcinoma, sebaceous gland carcinoma, squamous cell carcinoma and malignant melanoma. Cytologic examination of the fine needle aspiration and biopsy samples may reveal a specific type of neoplasm. All cancers from the eyelid and eye globe need to be removed. Histologic examinations of incised masses are recommended.
Źródło:
Okulistyka Weterynaryjna. e-kwartalnik dla lekarzy i studentów weterynarii; 2012, 2
2082-9256
Pojawia się w:
Okulistyka Weterynaryjna. e-kwartalnik dla lekarzy i studentów weterynarii
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Kardiomiopatie pierwotne u psów i kotów
Primary cardiomyopathies in dogs and cats
Autorzy:
Sapierzynski, R.
Powiązania:
https://bibliotekanauki.pl/articles/862309.pdf
Data publikacji:
2013
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
psy
koty
choroby zwierzat
choroby serca
kardiomiopatie
kardiomiopatia przerostowa
kardiomiopatia rozstrzeniowa
kardiomiopatia restrykcyjna
arytmogenna kardiomiopatia prawej komory
objawy chorobowe
zmiany patologiczne
badania histopatologiczne
Źródło:
Życie Weterynaryjne; 2013, 88, 12
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Nowotwory tkanki barwnikotwórczej gałki ocznej u psów i kotów
Autorzy:
Sapierzynski, R.
Powiązania:
https://bibliotekanauki.pl/articles/9914.pdf
Data publikacji:
2013
Wydawca:
Okulistyka Weterynaryjna
Tematy:
okulistyka weterynaryjna
psy
koty
nowotwory oka
nowotwory wewnatrzgalkowe
nowotwory z tkanki barwnikotworczej
czerniaki
melanocytoma rabka rogowki
melanocytoma teczowki
melanocytoma blony naczyniowej
wystepowanie
objawy chorobowe
diagnostyka
leczenie
Opis:
Ocular melanoma and melanocytoma are the most common tumors that occurs in dogs and cats. Ocular melanomas are known to be malignant in cats, but melanomas are mostly benign in dogs and have a low incidence of metastasis. In dogs melanomas are locally invasive, and the prognosis is poor when they spread to destroy the eyeball. Some important tumors are: limbal melanocytoma, uveal melanocytoma and diffuse iris melanomas in the cats. These tumors can cause glaucoma or uveitis of the eyeball. Therefore, early diagnosis is important for achieving a good prognosis for dogs and cats with ocular melanoma.
Spośród nowotworów gałki ocznej u psów i kotów stosunkowo częstymi zmianami są te, które wywodzą się z tkanki barwnikotwórczej. Do najważniejszych nowotworów w tej lokalizacji zalicza się melanocytomy rąbka rogówki, melanocytomy błony naczyniowej oraz rozsiane czerniaki tęczówki u kotów. Zmiany charakteryzują się różnym pochodzeniem, obrazem histologicznym, a także zachowaniem biologicznym. Poza obecnością samego guza, wśród objawów klinicznych dominują niekiedy objawy będące konsekwencją rozwoju powikłań wewnątrzgałkowych, takich jak, jaskra, czy nie poddające się leczeniu zapalenie błony naczyniowej oka.
Źródło:
Okulistyka Weterynaryjna. e-kwartalnik dla lekarzy i studentów weterynarii; 2013, 1
2082-9256
Pojawia się w:
Okulistyka Weterynaryjna. e-kwartalnik dla lekarzy i studentów weterynarii
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Osteochondroza u koni. Część II. Rozpoznawanie i rokowanie
Osteochondrosis in horses. Part II. Diagnosis and prognosis
Autorzy:
Kliczkowska, K.
Bereznowski, A.
Sapierzynski, R.
Powiązania:
https://bibliotekanauki.pl/articles/858291.pdf
Data publikacji:
2013
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
konie
choroby zwierzat
osteochondroza
diagnostyka
badania radiologiczne
badania histopatologiczne
ultrasonografia
biomarkery
mikrotomografia komputerowa
rokowanie
Źródło:
Życie Weterynaryjne; 2013, 88, 12
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 84

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