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Wyszukujesz frazę "Saluk, Joanna" wg kryterium: Autor

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    Wyświetlanie 1-6 z 6
    Tytuł:
    Stres oksydacyjny – reaktywne formy tlenu i azotu w patogenezie zaburzeń układu krążenia
    Oxidative stress – reactive oxygen and nitrogen species in the pathogenesis of cardiovascular disorders
    Autorzy:
    Kołodziejczyk, Joanna
    Saluk, Joanna
    Wachowicz, Barbara
    Powiązania:
    https://bibliotekanauki.pl/articles/1038430.pdf
    Data publikacji:
    2011
    Wydawca:
    Śląski Uniwersytet Medyczny w Katowicach
    Tematy:
    stres oksydacyjny
    choroby układu krążenia
    nadtlenoazotyn
    oxidative stress
    cardiovascular diseases
    peroxynitrite
    Opis:
    The generation of reactive oxygen and nitrogen species is a part of normal metabolism and under physiological conditions undergoes a strict control by a variety of enzymatic and non-enzymatic anti-oxidative mechanisms. However, under pathological conditions, the enhanced production of free radicals and non-radical oxidants may be overwhelm the anti-oxidative defence, leading to oxidative stress and irreversible damage of cells and tissues. It has been established, that increased production of reactive oxygen and nitrogen species has been implicated in the development of cardiovascular system-related disorders, including hypertension, atherosclerosis, diabetes, and ischemia-reperfusion injury. The presented review is a brief insight on the role of oxidative stress in the pathogenesis and progression of cardiovascular diseases, related to haemostasis disturbances and endothelium dysfunction.
    Powstawanie reaktywnych form tlenu i azotu jest częścią prawidłowych przemian biochemicznych i w warunkach fizjologicznych podlega ścisłej kontroli przez system licznych mechanizmów antyoksydacyjnych. W warunkach patologicznych dochodzi jednak do zwiększenia generowania zarówno wolnych rodników, jak i nierodnikowych czynników utleniających, co przewyższa możliwości obrony antoksydacyjnej organizmu. Pojawiający się stres oksydacyjny prowadzi do nieodwracalnych uszkodzeń komórek i tkanek. Wiadomo, że reaktywne formy tlenu i azotu są zaangażowane w rozwój wielu zaburzeń związanych z układem sercowo-naczyniowym, takich jak miażdżyca, nadciśnienie, cukrzyca czy uszkodzenia związane z niedokrwieniem serca i reperfuzją. Prezentowana praca stanowi krótki przegląd dostępnych danych, dotyczących biochemicznych podstaw udziału stresu oksydacyjnego w patogenezie i rozwoju wybranych chorób układu sercowo-naczyniowego.
    Źródło:
    Annales Academiae Medicae Silesiensis; 2011, 65, 4; 63-69
    1734-025X
    Pojawia się w:
    Annales Academiae Medicae Silesiensis
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The mutual cooperation of blood platelets and lymphocytes in the development of autoimmune thyroid diseases
    Autorzy:
    Tomczyńska, Małgorzata
    Saluk-Bijak, Joanna
    Powiązania:
    https://bibliotekanauki.pl/articles/1038518.pdf
    Data publikacji:
    2018
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    autoimmune thyroid diseases
    autoantibodies
    blood platelets
    chronic inflammation
    lymphocytes
    Opis:
    Autoimmune thyroid diseases include several distinct clinical entities, mainly Graves' disease and Hashimoto's thyroiditis. An incompetent immune response directed against the body's own tissues, and the production of antibodies against specific cell antigens accompanied by chronic inflammation, all occur in autoimmune thyroid diseases. The autoimmune process is induced by genetic and environmental factors that are difficult to identify and generates the development of concomitant diseases in other systems. Leukocyte activation and overproduction of inflammatory mediators, as well as improper levels of thyroid hormones, play an essential role in the chronic course of these diseases. The development of autoimmune thyroid diseases results from the impairment of the regulatory and suppressor functions of T-cells or NK cells and activation of B cells, or from the changes in the number of those cells. Many reports have shown the significant role of platelet-leukocyte interaction in inflammation. Autoantibodies react with target antigens in different kinds of cells, including blood platelets, and autoimmune processes can modulate the mutual cooperation of blood platelets and lymphocytes. The activity of blood platelets and lymphocytes is reciprocally regulated. It has been suggested that blood platelets can influence lymphocyte function by direct contact with receptors, and indirectly via soluble mediators. The interactions of platelet-immune cells (neutrophils, monocytes, lymphocyte and dendritic cells) can have a potent enhancing effect on immune cells functions.
    Źródło:
    Acta Biochimica Polonica; 2018, 65, 1; 17-24
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    β-glukan drożdży Saccharomyces cerevisiae - naturalny stymulator układu immunologicznego
    β-Glucan from Saccharomyces cerevisiae - the natural stimulator of immune system
    Autorzy:
    Saluk-Juszczak, Joanna
    Królewska, Karolina
    Powiązania:
    https://bibliotekanauki.pl/articles/1195533.pdf
    Data publikacji:
    2010
    Wydawca:
    Polskie Towarzystwo Przyrodników im. Kopernika
    Opis:
    In resent years, increased attention has been paid to b-glucans isolated from the cell walls of fungi that act as nonspecific modulators of immune system. b-glucan, a cell wall polysaccharide in many microorganism, fungi and algae, is a well- known biological response modifier (BRM). The cell wall of Saccharomyces cerevisiae consists of approximately 29-64% b-glucans. b-glucan from Saccharomyces cerevisiae possesses the strong positive influence on the immune system, resulting in antibacterial, wound-healing and antitumor activities. It is known that the immunomodulatory effects of b-glucans are influenced by their degree of branching, polymer lengths and tertiary structure. Most fungal b-glucans exhibit immunomodulatory activity when administered intravenously or intraperitoneally. b-glucan may directly activate cells, stimulating their phagocytic and antimicrobial activities, including the production of reactive intermediates and proinflammatory mediators, cytokines and chemokines. b-glucan receptor activity has subsequently been reported on a variety of other leukocytes, including macrophages, neutrophils, eosinophils and NK cells, as well as on nonimmune cells including endothelial cells, alveoral epithelial cells and fibroblasts. In addition to these, b-glucan also exhibits antioxidative capabilities. It is one of natural substances, known as antioxidants, which are able to protect living organisms from the attack of reactive radical species and in this way to decrease the risk of several diseases.
    Źródło:
    Kosmos; 2010, 59, 1-2; 151-160
    0023-4249
    Pojawia się w:
    Kosmos
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Aktywność biologiczna lipopolisacharydu bakteryjnego
    The biological activity of bacterial lipopolisaccharide
    Autorzy:
    Saluk-Juszczak, Joanna
    Wachowicz, Barbara
    Powiązania:
    https://bibliotekanauki.pl/articles/945062.pdf
    Data publikacji:
    1999
    Wydawca:
    Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
    Opis:
    The purpose of this paper is to briefly review the structure and biological activity of bacterial endotoxin. Endotoxin or lipopolisaccharide (LPS) is the major component of the ou ter membranes of the cell walls of Gramm-negative bacteria. LPS consists of two parts: the hydrophobic lipid A and hydrophylic polysaccharide with contrasting chemical and physical properties. The toxic activity is principally due to its lipid A moiety. LPS is capable of inducing stimulation of immunological system acting on monocytes, macrophages, granulocytes, platelets and endothelial cells leading to the release of inflammatory mediators: eicosanoids, cytokines, chemokines, adhesion molecules, reactive free radicals, platelet activating factor (PAF) and NO'. In the circulation LPS may bind to plasme components such as high-density lipoproteins (HDL) or LPS binding protein (LBP). This complex interacts with a high affinity receptor CD14 expressed on leukocytes, monocytes and macrophages resulting in activation of these cells and inducing pathophysiological effects such as inflammation, septic shock and death. The consequences for the host of all these events are dependent on the extent of LPS exposure and the status of the host defense mechanisms.
    Źródło:
    Acta Universitatis Lodziensis. Folia Biochimica et Biophysica; 1999, 14
    0208-614X
    Pojawia się w:
    Acta Universitatis Lodziensis. Folia Biochimica et Biophysica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Żywność funkcjonalna - rola nutraceutyków w profilaktyce chorób układu krążenia
    Functional food - a role of nutraceuticals in cardiovascular disease prevention
    Autorzy:
    Saluk-Juszczak, Joanna
    Kołodziejczyk, Joanna
    Babicz, Karolina
    Królewska, Karolina
    Powiązania:
    https://bibliotekanauki.pl/articles/1195938.pdf
    Data publikacji:
    2010
    Wydawca:
    Polskie Towarzystwo Przyrodników im. Kopernika
    Opis:
    The primary role of diet is to provide sufficient nutrients to meet the nutritional requirements of an individual, but there is now increasing scientific evidence supporting the hypothesis that some food components have beneficial effects over and above the provision of the basic nutrients. Foods with the plant origin, besides of numerous nutrients contain many non-nutritive compounds, which may prevent many diet-related diseases, such as cardiovascular diseases or cancers. Plants produce a large number of phenolic compounds as secondary metabolites that may play a role in reducing the risk of disease or in improving the health. Many traditional food products including fruits, vegetables, soya, whole grains and milk have been found to contain components with potential health benefits beyond basic nutritive value. Additionally, new foods are being developed to enhance or incorporate these beneficial components for their health benefits or desirable physiological effects. Rapid advances in food science and technology and consumer interest in functional foods has increased during the late twentieth century. The concept of functional foods was born in Japan and then the concepts of foods, developed specifically to promote health or reduce the risk of disease were introduced in Europe. Generally, functional foods are considered as those intended to be consumed as a part of the normal diet and contain biologically active components, and offer the potential enhancement of health or reduced risk of disease. Functional foods include products that contain specific minerals, vitamins, fatty acids or dietary fibre, foods with added biologically active substances such as phytochemicals or other antioxidants and probiotics with the live beneficial cultures. A variety of functional foods have been found to be potentially beneficial in the prevention and treatment of cardiovascular disease, which is the main cause of mortality in the world. These foods administered in adequate amounts may result in the decrease of cardiovascular diseases risk, at least by several potential mechanisms: lowering blood lipid levels, improving arterial compliance, reducing low-density lipoprotein oxidation, decreasing plaque formation, scavenging free radicals, and inhibiting platelet aggregation.
    Źródło:
    Kosmos; 2010, 59, 3-4; 527-538
    0023-4249
    Pojawia się w:
    Kosmos
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ekspresja P-selektyny na powierzchni płytek krwi indukowana endotoksyną bakteryjną Proteus mirabilis
    P-selectin expression on blood platelets induced by endotoxin Proteus mirabilis
    Autorzy:
    Saluk-Juszczak, Joanna
    Nowak, Paweł
    Golański, Jacek
    Wachowicz, Barbara
    Kaca, Wiesław
    Powiązania:
    https://bibliotekanauki.pl/articles/944985.pdf
    Data publikacji:
    2001
    Wydawca:
    Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
    Opis:
    P-selectin is stored in the a granules of blood platelets. Following platelet activation by different agonists, P-selectin is expressed on the cell surface where it mediates adhesion primarily to leucocytes.The aim of the study was to evaluate the direct effect of Proteus mirabilis lipopolysaccharides on the P-selectin expression on the platelet surface measured by cytometric method. The obtained results showed that LPS in vitro induced the expression of P-selectin (CD62) on platelets. It indicates that endotoxin from Gram-negative bacteria can activate blood platelets.
    Źródło:
    Acta Universitatis Lodziensis. Folia Biochimica et Biophysica; 2001, 15
    0208-614X
    Pojawia się w:
    Acta Universitatis Lodziensis. Folia Biochimica et Biophysica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-6 z 6

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