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Wyświetlanie 1-14 z 14
Tytuł:
Wkład Marcelego Landsberga w rozwój polskiej i światowej nefrologii
Marceli Landsberg’s Contribution to the Development of the Polish and World Nephrology
Autorzy:
OSTROWSKI, JANUSZ
RUTKOWSKI, BOLESŁAW
Powiązania:
https://bibliotekanauki.pl/articles/530491.pdf
Data publikacji:
2012
Wydawca:
Polskie Towarzystwo Historii Filozofii i Medycyny
Tematy:
profesor Marceli Landsberg
historia nefrologii i dializoterapii
Professor Marceli Landsberg
history of nephrology and dialysis treatment
Opis:
Nefrologia jest stosunkowo młodą dziedziną medycyny wywodzącą się z królowej nauk, interny. Początki ne- frologii na świecie sięgają bardzo odległych czasów, ale jej rozwój zauważalny jest szczególnie od okresu Odrodzenia, zwłaszcza w XVIII i XIX wieku, kiedy dokonało się wiele ważnych dla niej odkryć. W Polsce nefrologia jako podspecjalność medyczna zaczyna funkcjonować w pierwszych dekadach XX wieku. Najwięcej informacji z tego okresu dotyczy prac profesorów Witolda i Tadeusza Orłowskich, Jakuba Pensona czy Jana Roguskiego. Trochę w cieniu pozostawał dotychczas inny uczony, prof. Marceli Landsberg, dla którego zagadnienia dotyczące schorzeń układu moczowego, dzisiejszej nefrolo- gii, stanowiły jeden z najważniejszych rozdziałów pracy naukowej obejmującej diagnostykę laboratoryjną, patofizjologię nerek, w tym badania czynnościowe, patologię obrzęków i gospodarkę wodną, leczenie dietetyczne i w końcu pionierskie w skali światowej eksperymentalne prace nad zastosowaniem otrzewnej w leczeniu niewydolności nerek.
Having its roots in the queen of science — internal medicine, nephrology as such is a relatively new area of medical activity. Although the origins of nephrology date back to ancient times, its rapid development did not occur un- til the Age of the Enlightenment, particularly the 18th and 19th centuries when a number of discoveries paving the way for its further development were made. ^e first steps of nephrology in Poland as an autonomous field appear in the early decades of the 20th century with the works by Professors Witold and Tadeusz Orłowski, Jakub Penson or Jan Roguski among the most frequently quoted ones. However, another scientist, who remained somewhat in the background, rarely attracting the spotlight was Profes- sor Marceli Landsberg. ^e most prominent area of his sci- entific activity was the issue of the urinary system diseases, which is the field of interest taken over by the modern-day nephrology. Prof. Landsbergs work concerned laborato- ry diagnostics, renal pathophysiology, including function- al testing, oedema pathology and water balance, dietary treatment and, finally, his world-scale pioneering experi- mental works using the peritoneum to treat renal failure.
Źródło:
Archiwum Historii i Filozofii Medycyny; 2012, 75/1; 117-126
0860-1844
Pojawia się w:
Archiwum Historii i Filozofii Medycyny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Survival of tunneled hemodialysis catheters after percutaneous placement
Autorzy:
Weber, Ewa
Liberek, Tomasz
Wołyniec, Wojciech
Gruszecki, Marcin
Rutkowski, Bolesław
Powiązania:
https://bibliotekanauki.pl/articles/1038854.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
hemodialysis
tunneled catheter
survival
Opis:
Background. Tunneled catheters are becoming increasingly used as a permanent dialysis access. Easy way of insertion and good long-term patency make them competitive to fistulas in some groups of patients. Methods. Late complications and survival of 180 tunneled catheters inserted from June 2010 to December 2013 in 171 unselected hemodialysis patients were analyzed. Results. The cumulative time of observation was 2103.5 patient-months and median observation was 9 months (range of 0.5-45 months). Only 19 out of 180 catheters were removed due to complications (12 for infections, 4 due to malfunction and 3 because of mechanical damage). Majority of catheters were removed electively: 27 after maturation of arterio-venous fistula (AVF), 4 after kidney transplant, 5 after transfer to peritoneal dialysis and 3 due to the recovery of renal function. At the end of the observation, 58 catheters were still in use and 64 patients had died with functioning catheter. When censored for elective catheter removal and patient death, 88.2% of catheters survived for 1 year. Catheter survival was significantly better in older patients (over 65 years, in comparison to patients < 65 years, p = 0.046). Conclusions. Nearly 90% of all inserted catheters gave reliable dialysis access as long as it was needed. Among them, over 30% of the inserted catheters were in use at the end of the observation period, and over 30% of patients had died with a functioning catheter. The results of tunneled catheters survival are encouraging and they should be taken into consideration during decision-making on vascular access, especially in the older patients.
Źródło:
Acta Biochimica Polonica; 2016, 63, 1; 139-143
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Prolonged renal failure in the course of atypical ethylene glycol intoxication
Autorzy:
Liberek, Tomasz
Śliwarska, Julita
Czurak, Krzysztof
Perkowska-Ptasińska, Agnieszka
Weber, Ewa
Rutkowski, Bolesław
Powiązania:
https://bibliotekanauki.pl/articles/1039462.pdf
Data publikacji:
2013
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
ethylene glycol
intoxication
renal failure
Opis:
Ethylene glycol poisoning is not an uncommon cause of an acute renal injury. In this paper we present case of prolonged renal failure in the course of ethylene glycol intoxication. Due to the low dose of ingested ethylene glycol and concomitant ethanol consumption, the neurodepressive phase of the intoxication was rather mild and patient presented to the hospital on the ninth day after poisoning with established renal failure. The diagnosis of the specific cause of renal injury was facilitated by the renal biopsy.
Źródło:
Acta Biochimica Polonica; 2013, 60, 4; 661-663
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Nutritional predictors of mortality in prevalent peritoneal dialysis patients
Autorzy:
Malgorzewicz, Sylwia
Chmielewski, Michal
Kaczkan, Malgorzata
Borek, Paulina
Lichodziejewska-Niemierko, Monika
Rutkowski, Boleslaw
Powiązania:
https://bibliotekanauki.pl/articles/1038849.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
peritoneal dialysis
nutritional status
mortality
Opis:
Malnutrition remains one of the major predictors of mortality in peritoneal dialysis (PD) patients. The aim of the study was to evaluate the nutritional status of prevalent PD patients, and to determine the best predictors of outcome among anthropometric and laboratory indices of nutrition. The study included 106 prevalent PD patients from a single university-based unit. Anthropometric assessment at baseline included: body mass, body mass index (BMI), skinfold thickness, lean body mass (LBM), content of body fat (%F), mid-arm muscle circumference (MAMC). Laboratory analysis comprised of albumin and total cholesterol. Additionally, each patient underwent a subjective global assessment (SGA). The patients were followed for 36 months. Survival analyses were made with the Kaplan-Meier survival curve and the Cox proportional hazard model. Following SGA, malnutrition was diagnosed in 30 (28%) patients. Importantly, eight of the malnourished patients (27%) were nevertheless overweight or obese. Body weight and BMI showed complete lack of association with the outcome. In Kaplan-Meier analysis low: LBM, MAMC, albumin and cholesterol were significantly related to mortality. Cox analysis revealed that, following adjustment, LBM below median was independently associated with poor outcome (hazard ratio [HR] 3.15, 95% confidence interval [CI] 1.17-8.49, p=0.02). Moreover, the lowest quartile of total cholesterol showed independent association with mortality (HR 8.68, CI 2.14-35.21, p<0.01). Malnutrition is prevalent in patients undergoing PD, and overweight/obesity does not preclude its appearance. The most valuable nutritional indices in predicting outcome in this cohort were LBM and total cholesterol concentration.
Źródło:
Acta Biochimica Polonica; 2016, 63, 1; 111-115
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Influence of megestrol acetate on nutrition and inflammation in dialysis patients - preliminary results
Autorzy:
Gołębiewska, Justyna
Lichodziejewska-Niemierko, Monika
Aleksandrowicz, Ewa
Majkowicz, Mikołaj
Łysiak-Szydłowska, Wiesława
Rutkowski, Bolesław
Powiązania:
https://bibliotekanauki.pl/articles/1040501.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
malnutrition
megestrol acetate
proinflammatory cytokines
Opis:
Malnutrition is a common clinical problem in dialysis patients. So far the management of malnutrition in this population has not been fully successful. The aim of the study was to evaluate the efficacy and safety of use of megestrol acetate suspension in malnourished dialysis patients. Twenty-six hypoalbuminemic (albumin ≤ 3.8 g/dl) dialysis patients took 160 mg of megestrol acetate daily for a period of two months. Anthropometry (dry weight, body mass index) and biochemical measurements of nutrition (serum albumin, triglycerides, total cholesterol) and inflammation (hsCRP, IL-1β, IL-6) were performed on a monthly basis. The treatment led to a statistically significant increase (P < 0.05) in anthropometry and albumin concentration, with no statistically significant changes in total cholesterol, triglycerides and indices of inflammation. Side effects included overhydration, diarrhoea and hyperglycaemia. Thus, megestrol acetate may be an effective therapeutic agent in improving the nutritional status of carefully selected dialysis patients, while it might not mitigate inflammation. Because of the prevalent side effects it must be monitored closely.
Źródło:
Acta Biochimica Polonica; 2009, 56, 4; 733-737
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Przewlekła choroba nerek – istotne informacje dla lekarza medycyny pracy
Chronic kidney disease – The relevant information for an occupational physician
Autorzy:
Renke, Marcin
Parszuto, Jacek
Rybacki, Marcin
Wołyniec, Wojciech
Rutkowski, Przemysław
Rutkowski, Bolesław
Walusiak-Skorupa, Jolanta
Dębska-Ślizień, Alicja
Powiązania:
https://bibliotekanauki.pl/articles/2162582.pdf
Data publikacji:
2017-12-05
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
przewlekła choroba nerek
orzecznictwo lekarskie
ocena zdolności do pracy
albuminuria
kierowanie pojazdami
praca na morzu
chronic kidney disease
medical certification
evaluation of fitness for work
driving
work at sea
Opis:
Przewlekła choroba nerek (PChN) od kilku lat jest wymieniana wśród chorób cywilizacyjnych podobnie jak otyłość, cukrzyca, choroby sercowo-naczyniowe i nadciśnienie tętnicze. Szacuje się, że w Polsce na różne stadia tej choroby może cierpieć ponad 4 mln ludzi. Może ona być również następstwem wszystkich pozostałych chorób cywilizacyjnych. Jednocześnie warto dodać, że problemy nefrologiczne są coraz częściej uwzględniane w nowoczesnym orzecznictwie lekarskim. Celem pracy jest m.in. poprawa bezpiecznego dostępu do rynku pracy pacjentów z chorobami nerek. Przewlekła niewydolność nerek w stopniu zaawansowania, który może stanowić zagrożenie w sytuacji kierowania pojazdami, jest wymieniana jako przeciwwskazanie zdrowotne do kierowania pojazdami w przepisach prawnych obowiązujących w naszym kraju od 2014 r. Również w załączniku do Rozporządzenia Ministra Zdrowia z dnia 9 grudnia 2015 r. w sprawie warunków zdrowotnych wymaganych od marynarzy do wykonywania pracy na statku morskim wymieniono kody N17–N19 według klasyfikacji ICD-10 (International Classification of Diseases – Międzynarodowej Klasyfikacji Chorób), odpowiadające ostrej i przewlekłej oraz nieokreślonej niewydolności nerek, które należy wziąć pod uwagę przy kwalifikacji pracowników do pracy na morzu. Med. Pr. 2018;69(1):67–75
For a number of years chronic kidney disease (CKD) has been listed in the group of lifestyle diseases, such as obesity, diabetes, cardiovascular disease and hypertension. It is estimated that in Poland more than 4 million people may suffer from various stages of CKD. Chronic kidney disease may also be a consequence of all the other civilization diseases. At the same time it is worth noting that nephrological problems are increasingly being taken into account in modern medical certification. The aim of this work is, among other things, to improve safe access to the labor for patients with kidney diseases. In the legislation existing in our country since 2014 it is stated that chronic renal failure is a potential health contraindication to driving. Also in the annex to the Regulation of the Minister of Health dated 9 December 2015 on health conditions required for seafarers to work on a seagoing ship, it is said that ICD-10 codes (International Classification of Diseases) corresponding to acute and chronic renal failure (N17–N19) should be taken into account when qualifying employees to work at sea. Med Pr 2018;69(1):67–75
Źródło:
Medycyna Pracy; 2018, 69, 1; 67-75
0465-5893
2353-1339
Pojawia się w:
Medycyna Pracy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Atorvastatin improves tubular status in non-diabetic patients with chronic kidney disease - placebo controlled, randomized, cross-over study
Autorzy:
Renke, Marcin
Tylicki, Leszek
Rutkowski, Przemysław
Neuwelt, Alexander
Larczyński, Wojciech
Ziętkiewicz, Marcin
Aleksandrowicz, Ewa
Łysiak-Szydłowska, Wiesława
Rutkowski, Bolesław
Powiązania:
https://bibliotekanauki.pl/articles/1040322.pdf
Data publikacji:
2010
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
proteinuria
kidney
tubular injury
chronic kidney disease
Atorvastatin
Opis:
Background. There is evidence that dyslipidemia is associated with chronic kidney disease (CKD) and it has been implicated in the progression of renal damage. Optimal management of dyslipidemia should therefore lead to renal benefits. A number of experimental models demonstrate a beneficial effect of statins in ameliorating renal damage. However, the exact mechanism by which statins protect against renal damage remains unclear. Methods. In a placebo-controlled, randomized, cross-over study we evaluated the influence of atorvastatin (ATO) 40 mg/day added to the renin-angiotensin-aldosterone systeme (RAAS) blockade on proteinuria and surrogate biomarkers of tubular damage or injury in 14 non-diabetic patients with proteinuria (0.4-1.8 g per 24 h) with normal or declined kidney function (eGFR 55-153 ml/min). In the eight-week run-in period, therapy using angiotensin converting enzyme inhibitors (ACEI) and/or angiotensin II subtype 1 receptor antagonists (ARB) was adjusted to achieve a blood pressure below 130/80 mm Hg. Next, patients were randomly assigned to one of two treatment sequences: ATO/washout/placebo or placebo/washout/ATO. Clinical evaluation and laboratory tests were performed at the randomization point and after each period of the study. The primary end point of this study was a change in proteinuria measured as 24-h urine protein excretion (DPE). Secondary end points included urine N-acetyl-β-d-glucosaminidase (NAG) and α1-microglobulin (α1m) excretion. Results. The ATO therapy significantly reduced urine excretion of α1m (p=0.033) and NAG (p=0.038) as compared to placebo. There were no differences in proteinuria, blood pressure, eGFR and serum creatinine between the ATO and placebo groups. Conclusion. Atorvastatin treatment is safe and improves biomarkers of tubular damage or injury in non-diabetic patients with CKD.
Źródło:
Acta Biochimica Polonica; 2010, 57, 4; 547-552
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of pentoxifylline on proteinuria, markers of tubular injury and oxidative stress in non-diabetic patients with chronic kidney disease - placebo controlled, randomized, cross-over study
Autorzy:
Renke, Marcin
Tylicki, Leszek
Rutkowski, Przemysław
Knap, Narcyz
Ziętkiewicz, Marcin
Neuwelt, Alexander
Aleksandrowicz, Ewa
Łysiak-Szydłowska, Wiesława
Woźniak, Michał
Rutkowski, Bolesław
Powiązania:
https://bibliotekanauki.pl/articles/1040438.pdf
Data publikacji:
2010
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
pentoxifylline
oxidative stress
kidney
chronic kidney disease
proteinuria
tubular injury
Opis:
Background: Inhibition of the renin-angiotensin-aldosterone system (RAAS) with angiotensin converting enzyme inhibitors (ACEI) and/or angiotensin II subtype 1 receptor antagonists (ARB) is a common strategy used in the management of patients with chronic kidney disease (CKD). However, there is no universal therapy that can stop progression of CKD. Pentoxifylline (PTE) is a non-specific phosphodiesterase inhibitor with anti-inflammatory properties. It has been reported to have promising effects in CKD treatment. Methods: In a placebo-controlled, randomized, cross-over study we evaluated the influence of PTE (1200 mg/day) added to RAAS blockade on proteinuria, surrogate markers of tubular injury and oxidative stress-dependent products in 22 non-diabetic patients with proteinuria (0.4-4.3 g per 24h) with normal or declined kidney function [eGFR 37-178 mL/min]. In an eight-week run-in period, therapy using ACEI and/or ARB was adjusted to achieve a blood pressure below 130/80 mm Hg. Next, patients were randomly assigned to one of two treatment sequences: PTE/washout/placebo or placebo/washout/PTE. Clinical evaluation and laboratory tests were performed at the randomization point and after each period of the study. Results: The PTE therapy reduced proteinuria (by 26%) as compared to placebo. There were no differences in α1-microglobulin, urine excretion of N-acetyl-β-d-glucosaminidase (NAG), hsCRP, the urinary excretion of 15-F2t-isoprostane, blood pressure (BP), eGFR and serum creatinine between the PTE and placebo groups. Conclusion: Pentoxifylline may decrease proteinuria in non-diabetic patients with CKD.
Źródło:
Acta Biochimica Polonica; 2010, 57, 1; 119-123
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The use of over-the-counter analgesics in patients with chronic kidney disease
Autorzy:
Jakimowicz-Tylicka, Marzena
Chmielewski, Michał
Kuźmiuk-Glembin, Izabella
Skonieczny, Piotr
Dijakiewicz, Grażyna
Zdrojewska, Grażyna
Rutkowski, Bolesław
Tylicki, Leszek
Dębska-Ślizień, Alicja
Powiązania:
https://bibliotekanauki.pl/articles/895741.pdf
Data publikacji:
2019-02-05
Wydawca:
Gdański Uniwersytet Medyczny
Tematy:
chronic kidney disease
analgesics
over-the-counter
Opis:
Background: Analgesics can be sold following medical prescription, but also as over-the-counter (OTC) medications. In patients with chronic kidney disease (CKD), their use could potentially be associated with increased risk of side-effects, due to impaired renal elimination. The aim was to evaluate the epidemiology and indications for the use of OTC analgesics, and the knowledge of their side-effects in patients with CKD. Material and methods: A cross-sectional, controlled survey on the use of OTC analgesic drugs was conducted among 180 CKD patients (stage 1-5, dialysis, kidney transplant), compared to 60 controls. Results: The proportion of patients using OTC analgesics on a regular basis was higher in the CKD group, compared to controls (18.9% vs. 10.0%, p<0.02). The major indications included musculoskeletal issues, followed by headaches and other. Subgroup analysis revealed that analgesic use was lowest among transplanted patients, in comparison to CKD stage 1-5, and dialysis subjects (10%, 20%, 26%, respectively, p=0.06). Less than half of CKD patients and controls declared any knowledge on potential side-effects of analgesic drugs (45.6% vs. 40.0%, NS). Conclusions: The use of OTC analgesics among patients with CKD is higher than in subjects without CKD, with the exception of transplanted patients. The knowledge on the potential side-effect of analgesics is limited.
Źródło:
European Journal of Translational and Clinical Medicine; 2018, 1, 2; 11-16
2657-3148
2657-3156
Pojawia się w:
European Journal of Translational and Clinical Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Dietary supplement use among patients with chronic kidney disease
Autorzy:
Jakimowicz-Tylicka, Marzena
Chmielewski, Michał
Kuźmiuk-Glembin, Izabella
Skonieczny, Piotr
Dijakiewicz, Grażyna
Zdrojewska, Grażyna
Rutkowski, Bolesław
Tylicki, Leszek
Dębska Ślizień, Alicja
Powiązania:
https://bibliotekanauki.pl/articles/1038410.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
dietary supplements
vitamins
minerals
chronic kidney disease
dialysis
toxicity
Opis:
Background. Dietary supplements (DS) are available over the counter, but patients with impaired renal function are specifically at risk for toxicity when consuming certain DS. The aim of this study was to evaluate the prevalence and characteristics of DS use in patients with chronic kidney disease (CKD). Material and methods. A cross-sectional, controlled DS use survey (22 questions) was conducted among 180 CKD patients (stage 1-5, dialysis, kidney transplant), with 60 patients without CKD serving as controls. Results. DS use did not differ significantly between subjects with and without CKD, unless the CKD patients were on dialysis. In the CKD group, 20% admitted to use DS regularly and 22% did not take the mat all. In the controls, DS consumption was 17% and 13%, respectively (NS). The DS use was higher among women ascompared to men (89% vs. 70%; p < 0.005), and people living in cities versus those living in the country side (81% vs. 63%; p < 0.05). DS most commonly used were: vitamins, minerals, and herbs. Major indications for DS use included: musculoskeletal issues, general health improvement and prevention of urinary tract infections. Subgroup analyses revealed that dialysis patients were characterized by a significantly higher DS use in comparison to CKD stage 1-5 subjects and renal transplant recipients. The decision to introduce DS was made by the physician in 54% of cases; by a pharmacist in 9% of cases, and by the patients themselves in 37%. Only 21% of patients with CKD, and 27% of subjects without CKD, declared knowledge of any possible side-effects associated with DS (NS). Conclusions. The use of DS among patients with CKD is similar to patients without CKD, with the exception of those on dialysis. Vitamins and minerals were the most commonly reported DS consumed. The knowledge on potential side-effectof DS was limited to approximately one-fourth of those surveyed.
Źródło:
Acta Biochimica Polonica; 2018, 65, 2; 319-324
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Aliskiren reduces albuminuria after kidney transplantation
Autorzy:
Tylicki, Leszek
Debska-Slizien, Alicja
Lizakowski, Slawomir
Przybylska, Milena
Heleniak, Zbigniew
Renke, Marcin
Chamienia, Andrzej
Biedunkiewicz, Bogdan
Rutkowski, Przemyslaw
Małgorzewicz, Sylwia
Rutkowski, Boleslaw
Powiązania:
https://bibliotekanauki.pl/articles/1038634.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
albuminuria
aliskiren
kidney transplantation
renoprotection
Opis:
Background: The renoprotective effects of the direct renin inhibitor, aliskiren, in renal transplant recipients have been supposed, but not finally proven. We performed an exploratory double-blind, losartan controlled, cross-over study to evaluate the influence of aliskiren, direct renin inhibitor, on albuminuria and other surrogate markers of kidney injury in patients after renal transplantation. The safety of this therapy was also evaluated. Method: 16 of 18 patients (12 M, 4 F), 48.3 ± 9.0 years, 57.7 ± 9.1 months after kidney transplantation, with hypertension and stable serum creatinine 1.4 ± 0.08 mg/dl without proteinuria, completed the protocol. Each patient underwent two 8-week treatment periods (one with 150 mg of aliskiren, and one with 50 mg of losartan) in random order, allowing an 8-week placebo washout between them. Results: There were no differences in albuminuria, transforming growth factor β-1 and 15-F2t-isoprostanes urine excretion between aliskiren and losartan. Creatinine serum level, eGFR, 24 h systolic and 24 h diastolic blood pressure were stable through the study. There were no differences in haemoglobin and potassium serum concentration between studied drugs. Conclusion: Aliskiren decreases albuminuria in renal transplant recipients with clinically minimal side effects. The effect does not differ from that of losartan.
Źródło:
Acta Biochimica Polonica; 2017, 64, 2; 221-226
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Perspektywiczny model systemu obronnego RP [Rzeczypospolitej Polskiej] "Kierunki"
Współwytwórcy:
Kulczycki, Roman. Opracowanie
Włodarski, Andrzej (organizacja i zarządzanie). Opracowanie
Nożko, Kazimierz. Opracowanie
Balcerowicz, Bolesław (1943- ). Opracowanie
Madejski, Andrzej. Opracowanie
Kaczmarek, Julian. Opracowanie
Skrzyp, Julian. Opracowanie
Stańczuk, Stanisław. Opracowanie
Wocial, Janusz. Opracowanie
Komański, Aleksander. Opracowanie
Gogolewski, Jerzy. Opracowanie
Kawczyński, Krzysztof. Opracowanie
Kamiński, Tadeusz. Opracowanie
Kowalewski, Marian. Opracowanie
Teresiak, Krzysztof. Opracowanie
Wróblewski, Ryszard. Opracowanie
Łuczak, Maciej. Opracowanie
Świątnicki, Wacław. Opracowanie
Szymański, Roman. Opracowanie
Bobkowski, Andrzej. Opracowanie
Makowski, Andrzej. Opracowanie
Marczak, Józef. Opracowanie
Rutkowski, Cezary. Opracowanie
Rzeszutko, Wilhelm. Opracowanie
Kurant, Andrzej. Opracowanie
Kalinowski, Romuald. Opracowanie
Data publikacji:
1991-1992
Wydawca:
Warszawa : AON
Tematy:
Obronność państwa system Polska do 1992 r.
Strategia wojenna Polska do 1992 r.
Wojsko organizacja Polska do 1992 r.
Logistyka wojskowa do 1992 r.
Przemysł wojenny konwersja do 1992 r.
Dowodzenie strategiczne do 1992 r.
Wojska lądowe organizacja Polska do 1992 r.
Obrona cywilna Polska do 1992 r.
Szkolnictwo wojskowe organizacja Polska do 1992 r.
Siły powietrzne organizacja Polska do 1992 r.
Marynarka wojenna organizacja Polska do 1992 r.
Obrona Terytorium Kraju organizacja Polska do 1992 r.
Obrona regionalna do 1992 r.
Wojska szybkiego reagowania do 1992 r.
Opis:
Verso k. nie zadrukowane.
Stanowi temat problemu naukowego pt.: Kierunki doskonalenia systemu obronnego RP pk. "Kierunki".
Dostawca treści:
Bibliografia CBW
Książka
    Wyświetlanie 1-14 z 14

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