- Tytuł:
- Tridentate hydrazido-hydrazones vanadium complexes. Synthesis, properties and biological activity
- Autorzy:
-
Szklarzewicz, Janusz
Jurowska, Anna
Hodorowicz, Maciej
Matoga, Dariusz
Gryboś, Ryszard
Filipek, Barbara
Sapa, Jacek
Głuch-Lutwin, Monika
Mordyl, Barbara
Kazek, Grzegorz - Powiązania:
- https://bibliotekanauki.pl/articles/93144.pdf
- Data publikacji:
- 2019
- Wydawca:
- Państwowa Wyższa Szkoła Zawodowa w Tarnowie
- Tematy:
-
vanadium
complex
Schiff base
structure
hydrazide
biological activity
wanad
kompleks
baza Schiffa
Struktura
hydrazyd
aktywność biologiczna - Opis:
- Nine new vanadium complexes, with tridentate Schiff base ligand based on 3,5-di-tertbutyl-2-hydroxybenzaldehyde and different hydrazides, are described and characterized. The X-ray crystal structure of complex 8 shows distorted octahedral geometry of vanadium, with ONO ligand in equatorial position. The tridentate Schiff base ligand forms six membered and five-membered chelate rings at the V(V) acceptor center, with the corresponding bite angles being 82.97(9)˚ and 74.48(9)˚. The molecules are gathered by means of intermolecular OH...N hydrogen bond and layered by π...π interactions involving the pyridine and phenolate rings. Such interactions expand the structure along the crystallographic a axis. The complexes were characterized by the elemental analyses, IR, UV-Vis, EPR spectroscopy, cyclic voltammetry, thermogravimetry and magnetic susceptibility measurements. The stabilization role of co-ligands is discussed. The cytotoxicity versus HepG2 hepatocytes and inhibition of human recombinant PTP1B was studied.
- Źródło:
-
Science, Technology and Innovation; 2019, 4, 1; 9-20
2544-9125 - Pojawia się w:
- Science, Technology and Innovation
- Dostawca treści:
- Biblioteka Nauki
Artykuł