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    Wyświetlanie 1-9 z 9
    Tytuł:
    Badanie zjawiska kawitacji w pompach wyporowych
    The Study of Cavitation Effect in Positive Displacement Pumps
    Autorzy:
    Kudźma, Z.
    Mackiewicz, O.
    Powiązania:
    https://bibliotekanauki.pl/articles/275599.pdf
    Data publikacji:
    2016
    Wydawca:
    Sieć Badawcza Łukasiewicz - Przemysłowy Instytut Automatyki i Pomiarów
    Tematy:
    kawitacja
    pompa wyporowa
    hałas
    cavitation
    positive displacement pump
    noise
    Opis:
    W artykule omówiono zjawisko kawitacji w pompach wyporowych. Podano warunki i miejsce powstawania zjawiska. Badania własne autorów oraz studia literaturowe obrazują wizualizację zjawiska kawitacji. Dokonano identyfikacji efektu akustycznego towarzyszącego procesowi rozwoju kawitacji w pompach – wielotłoczkowej i zębatej.
    In the paper main attention was focused on cavitation effect in positive displacement pumps. Cavitation conditions and areas of its arising were defined. Author’s own studies and literature review were helpful for cavitation visualization. An acoustic effect accompanied with cavitation development in pumps (multipiston pump, gear pump) was identified.
    Źródło:
    Pomiary Automatyka Robotyka; 2016, 20, 1; 17-23
    1427-9126
    Pojawia się w:
    Pomiary Automatyka Robotyka
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Charakterystyka endogennych inhibitorów enzymów rozkładających enkefaliny
    Characteristic of the endogenous enkephalin degrading enzymes inhibitors
    Autorzy:
    Sobocińska, M.
    Maćkiewicz, Z.
    Powiązania:
    https://bibliotekanauki.pl/articles/171530.pdf
    Data publikacji:
    2014
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Tematy:
    inhibitory
    inhibitory enzymów rozkładających enkefaliny
    Els
    endogenne inhibitory enzymów rozkładających enkefaliny
    opiody
    peptydy
    ból
    środki przeciwbólowe
    inhibitors
    endogenous enkephalin degrading enzymes inhibitors
    opioid
    peptides
    pain
    analgesicagents
    Opis:
    Management of acute and chronic pain has always been a key area of clinical research. Pain and stress stimulation may cause an increase in the level of endogenous opioids in the body. Endogenous enkephalins activate opioid receptors in the brain, leading to the analgesic effect. Enkephalinases inactivate endogenous opioids, abolishing their activity. Enkephalin degrading enzyme inhibitors (EIs) in turn inhibit these enzymes, preventing them from degrading endogenous enkephalins what leads to analgesia. The enkephalin degrading enzyme inhibitors seem to be promising analgesic agents [2]. Analgesic effect of EIs has been discovered recently and their therapeutic potential has not been effectively investigated yet. The main advantage of enkephalinase inhibitors is that they do not show adverse effects characteristic for opioids. EIs play an important role in modulating nociception, so they are potential agents for the treatment of acute and chronic pain. They often possess also additional antidiarrheal, antidepressant and anticancer properties [3]. The potential EIs targets appear to be aminopeptidase N (APN), dipeptidyl peptidase III (DPP III), angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP) [4]. EIs may be broadly classified as endogenous and those that are obtained synthetically [4]. The purpose of this work is to present a review of endogenous enkephalinase inhibitors: sialorphin, opiorphin, and spinorphin. Sialorphin (Gln-His-Asn-Pro-Arg) is synthesized predominantly in the submandibular gland and prostate of adult rats in response to androgen steroids and is released locally and systemically in response to stress. Sialorphin protects endogenous enkephalins released after nociceptive stimuli by inhibiting NEP in vivo. Sialorphin prevents spinal and renal NEP from breaking down substance P and Met-enkephalin in vitro. Sialorphin suppressed pain sensation for both chemical- -induced inflammation and acute physical pain [8, 9, 12]. Opiorphin (Gln-Arg-Phe-Ser-Arg) is an endogenous chemical compound first isolated from human saliva. Opiorphin is a natural analgesic. Opiorphin protects enkephalins from degradation by human neutral endopeptidase and aminopeptidase N. Opiorphin is closely related to the rat sialorphin peptide [12, 13, 19]. Spinorphin (Leu-Val-Val-Tyr-Pro-Trp-Thr) has been isolated from the bovine spinal cord as an endogenous inhibitor of enkephalin - degrading enzymes. Spinorphin is an antagonist of the P2X3 receptor and a weak partial agonist/antagonist of the FP1 receptor [24, 25, 26].
    Źródło:
    Wiadomości Chemiczne; 2014, 68, 3-4; 317-327
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Damage development of Inconel 718 due to laboratory simulated creep
    Autorzy:
    Makowska, K.
    Brodecki, A.
    Mackiewicz, S.
    Kowalewski, Z. L.
    Powiązania:
    https://bibliotekanauki.pl/articles/949297.pdf
    Data publikacji:
    2018
    Wydawca:
    Polskie Towarzystwo Mechaniki Teoretycznej i Stosowanej
    Tematy:
    creep
    nickel superalloy
    microstructure
    pre-deformation
    hardness
    acoustic birefringence
    Opis:
    The paper presents an attempt of application of the acoustic birefringence coefficient for early stage degradation assessment of Inconel 718 nickel superalloy after short-term creep. It is shown that it can serve as a good damage sensitive parameter and, moreover, it can be well correlated with hardness variation.
    Źródło:
    Journal of Theoretical and Applied Mechanics; 2018, 56, 3; 893-896
    1429-2955
    Pojawia się w:
    Journal of Theoretical and Applied Mechanics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Metody wykorzystywane do wizualizacji śladów linii papilarnych
    Methods used to vizualize latent fingerprints
    Autorzy:
    Kołek-Kaczanowska, E. K.
    Kreczko, J.
    Maćkiewicz, Z.
    Powiązania:
    https://bibliotekanauki.pl/articles/172282.pdf
    Data publikacji:
    2014
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Tematy:
    linie papilarne
    ślady linii papilarnych
    daktyloskopia
    ujawnianie
    wizualizacja
    fingerprints
    dactyloscopy
    revealing
    visualization
    Opis:
    Dactyloscopy as one of the branches of forensic science deals with fingerprints identification of the individual human being. Fingerprints are in general invisible, therefore in order to set about the identification, we have to make them evident. To reveal hidden fingerprints, criminological technology uses physical methods, chemical reactions and even some biological processes. In this review, we present a set of methods that is being used in criminology to reveal fingerprints and other hidden traces. In search for potential fingerprints, objects are exposed to natural and artificial light sources since visual methods are most commonly used by criminology technicians. Further methods for revealing fingerprints are selected on the basis of type of surface, the trace was left on, and the substance forming the fingerprint. In his article we present the set of methods, commonly used to reveal fingerprints, featuring physical, chemical and physicochemical approaches [6]. Chemical methods: DFO, 1,2-IND and Ninhydin used for revealing fingerprints on absorptive surfaces, Amido Black, Hungarian Red, DAB and LCV used for detecting bloody fingerprints, DMAC used for revealing fingerprints on temperature-felt papers, RTX dioxide of ruthenium used to absorptive and nonabsorptive surfaces [9, 11, 14, 19, 22, 24, 26, 28, 30]. Next, we present physical methods among others optical methods which are helpful in revealing fingerprints for the naked eye and (if needed) enlarging optical devices. To achieve acceptable visibility, criminologists use various kinds of lamps and filters. Subsequently we present methods based on adhesion, that are based on adjoining the powder or suspension to sudoral-fatty substance. We present here methods based on the use of dactyloscopic powders, crystal violet which is appearing in the form of dark-green powder , SPR (Small Particle Reagent) – suspension of black MoS2 powder, Sticky-side Powder which composition is accessing iron oxide and aluminum, Wet Powder Black, composed of iron oxide and Wet Powder White (titanium dioxide). Tape-Glo (ready-made red-orange solution), Sudan Black B (in the solid state it is a powder of the black colour), Liquid-drox (yellow solution), fluorescent dyes: Ardrox P133D, Safranin O, chelate of europium and Basic Yellow 40 [31, 34–38]. The other methods are physicochemical methods: cyanoacrylate, iodine, physical developer and multi metal deposition [42, 45, 46]. As a result of technological development newer methods of visualizing latent fingerprints appear, replacing those previously used. Improvement of the methods of revealing latent fingerprints leads to better readability and in effect, makes police work easier.
    Źródło:
    Wiadomości Chemiczne; 2014, 68, 3-4; 279-315
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Peptydy penetrujące : rodzaje i mechanizmy przenikania przez błony komórkowe
    Cell-penetrating peptides : types and mechanisms of penetration
    Autorzy:
    Kawczyński, M. T.
    Kreczko-Kurzawa, J.
    Maćkiewicz, Z.
    Powiązania:
    https://bibliotekanauki.pl/articles/172725.pdf
    Data publikacji:
    2015
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Tematy:
    peptydy penetrujące
    penetratyna
    endocytoza
    amfipatyczność
    CPP
    cell-penetrating peptides
    penetratin
    endocytosis
    amphipaticity
    Opis:
    Before discovery of the Tat peptide over twenty years ago, it was assumed that large peptides and proteins do not penetrate cell membranes. After discovery of Tat, Penetratin [1, 2] and several other peptides of natural origin, able to cross the cell membranes in an energy-independent manner, the structural determinants of their cell-penetrating potency were established, including polycationic character, amphipaticity and presence of proline-rich motifs [3, 4]. Currently known cell-penetrating peptides of natural or synthetic origin are composed of 5 to 40 amino acid residues and belong to one of the three families: oligocationic, amphipatic or proline-rich and penetrate the biological membranes by endocytosis or other ways of direct translocation. Most of these translocation mechanisms are not exclusive and may occur simultaneously, and their contribution may be different for each peptide depending on the conditions (e.g. CPP concentration, pH, etc.). Most CPPs demonstrate little or no mammalian cell toxicity what makes them promising vectors for drug delivery. Such vectors might be useful for efficient internalization of compounds otherways poorly penetrating biological membranes. Novel CPP-effector conjugates may become effective anticancer or antimicrobial agents of a great potential for chemotherapy [3, 5]. In this short review we present a glimpse at the current state of knowledge concerning sub‑families, types and mechanisms of action of most prominent members of CPP family.
    Źródło:
    Wiadomości Chemiczne; 2015, 69, 1-2; 9-33
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Study of Composite Insulator Sheds Subjected to Wheel Test
    Autorzy:
    Mackiewicz, M.
    Mikulski, J. L.
    Wańkowicz, J.
    Kucharski, S.
    Ranachowski, P.
    Ranachowski, Z.
    Powiązania:
    https://bibliotekanauki.pl/articles/353096.pdf
    Data publikacji:
    2017
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    composite insulators
    silicone rubber
    wheel test
    electrical surface discharges
    tracking and erosions
    Opis:
    The paper presents investigation of the properties of the surface and the material stiffness – flexibility of series of samples taken from the sheds of the composite insulators. The insulators were previously subjected to wheel test. The wheel test and 1000 h salt fog test are regarded as alternative examination of the material resistance to the effects of electrical surface discharges. There were investigated two series of the samples of the composite insulators sheds. Examined specimens, made of HTV silicone rubber, were taken from the sheds of medium-voltage composite insulators of two different manufacturers. Insulators of both types passed the 1000 h salt fog test without reservation. Meanwhile, the wheel test can provide a basis for better distinguishing between physical properties of the tested materials. In the case of the insulators of one of the manufacturers the wheel test result was negative. Cross puncture effect of the sheds took place in several places. In addition, sheds were covered with dark coating of varying thicknesses. The results of the study indicated a significantly stronger influence of electrical and temperature factors on the sheds under investigations during the wheel test than in the case of the 1000 h salt fog test. It can be stated that these tests cannot be considered as alternative and it seems that wheel test enables better distinguishing between properties of the materials.
    Źródło:
    Archives of Metallurgy and Materials; 2017, 62, 2A; 679-686
    1733-3490
    Pojawia się w:
    Archives of Metallurgy and Materials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Sulphur in the Polish fertilization diagnositcs
    Siarka w polskiej diagnostyce nawozowej
    Autorzy:
    Skwierawska, M.
    Krzebietke, S.
    Jankowski, K.
    Benedycka, Z.
    Mackiewicz-Walec, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/14482.pdf
    Data publikacji:
    2014
    Wydawca:
    Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
    Opis:
    Over the years, researchers from Polish research centres have been improving analytical methods as well as plant and soil assays, designed to diagnose demands of crops for sulphur fertilization and to assess their supply with this element. In this article, the authors look back at the last 100 years of the Polish research on sulphur, in the context of analytical methods, soil and plant assays, and their application to assessments of crop fertilization requirements. Studies on diagnosing crops’ demand for sulphur fertilization have a long-standing tradition. Back in 1903, for example, Godlewski and Jentys wrote about nutritional demands of crops and about sulphur nutrition. For over a century since then, the analytical methods have changes, soil and plant assays have been designed and parameters have been established to facilitate assessment of plant nutrient demands. Sulphur-oxidizing autotrophic microorganisms or the fungi Aspergillus niger have been used for diagnosis. Another investigated possibility was monitoring the capacity of sulphur for migration, assayed in lisymetric experiments. The 1960s were a time when modifications of earlier turbimetric methods appeared. In addition, applications of the isotope 35S were checked as a sulphur marker enabling determination of the dynamics of this element in soil and in plants. With the passing of time, new technologies and measuring devices were developed. Some research centres implemented sulphur detection assays on soil and plant material with the following methods: ICP, GC, HPLC or XPF (x-ray fluorescent analysis). With respect to soil and plant tests, which admittedly are a very useful tool for monitoring the sulphur abundance in soil and nutritional demands of plants, it is now the time to state that they need further verification and calibration, in both pot and field experiments.
    Na przestrzeni lat w polskich ośrodkach naukowych badacze udoskonalali metody analityczne oraz testy roślinne i glebowe w celu diagnozowania potrzeb nawożenia siarką i oceny zaopatrzenia roślin w ten pierwiastek. Celem pracy była retrospektywna analiza 100 lat polskich badań nad siarką w kontekście metod analitycznych, testów glebowych i roślinnych oraz wykorzystania ich do oceny potrzeb nawozowych roślin. Polskie badania dotyczące diagnozowania potrzeb nawożenia siarką mają długą tradycję. Już w 1903 r. Godlewski i Jentys pisali o wymaganiach pokarmowych roślin i nawożeniu siarką. W ciągu 100 lat polskich badań zmieniały się metody analityczne, opracowano testy glebowe i roślinne oraz wskaźniki mające ułatwić ocenę potrzeb nawozowych roślin. Do diagnozy wykorzystywano mikroorganizmy autotroficzne utleniające siarkę elementarną czy grzyby Aspergillus niger. Badano możliwości migracji siarki w doświadczeniach lizymetrycznych. Lata 60. to zarówno modyfikacje metod turbidymetrycznych, jak i poszukiwania zastosowań izotopu 35S do znakowania siarki w celu oznaczania dynamiki siarki w glebie i roślinie. W miarę upływu czasu pojawiły się nowe technologie i aparatury pomiarowe. Niektóre ośrodki naukowe zainicjowały oznaczanie siarki w materiale glebowym i roślinnym za pomocą ICP, GC, HPLC czy XPF – metodą analizy fluorescencyjnej rentgenowskiej. W nawiązaniu do testów glebowych i roślinnych, które są bardzo przydatnym narzędziem w monitorowaniu zasobności gleb w siarkę i wymagań pokarmowych roślin, można na dzień dzisiejszy stwierdzić, że wymagają one dalszych weryfikacji i kalibracji zarówno na poziomie doświadczeń wazonowych, jak i badań polowych.
    Źródło:
    Journal of Elementology; 2014, 19, 1
    1644-2296
    Pojawia się w:
    Journal of Elementology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-9 z 9

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