- Tytuł:
-
Zmiany poziomu glutationu i aktywności transferazy glutationowej w płytkach krwi indukowane związkami selenu
Selenium - induced changes of GSH level and glutathione S-transferase activity in blood platelets - Autorzy:
-
Żbikowska, Halina
Krajewski, Tadeusz
Wachowicz, Barbara - Powiązania:
- https://bibliotekanauki.pl/articles/945026.pdf
- Data publikacji:
- 1997
- Wydawca:
- Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
- Opis:
- The effects of inorganic selenocompounds (sodium selenite and selenate) on the level of reduced glutathione, free sulfhydryl groups of proteins and the activity of S-glutathione transferase (GST) in pig blood platelets were studied. It was shown that selenite, contrary to selenate reduced the amounts of both GSH and -SH of platelet proteins. The concentration of GSH after one-hour treatment of platelets with a high dose of selenite (10-4 M) was reduced by 50%. A decrease in protein thiols was also significant. We observed that the activity of platelet GST was inhibited after incubation of these cells with a toxic dose of selenite but not selenate.
- Źródło:
-
Acta Universitatis Lodziensis. Folia Biochimica et Biophysica; 1997, 12
0208-614X - Pojawia się w:
- Acta Universitatis Lodziensis. Folia Biochimica et Biophysica
- Dostawca treści:
- Biblioteka Nauki