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Wyszukujesz frazę "Dyląg, Anna" wg kryterium: Autor


Wyświetlanie 1-6 z 6
Tytuł:
Carrier-state of D allele in ACE gene insertion/deletion polymorphism is associated with coronary artery disease, in contrast to the C677→T transition in the MTHFR gene.
Autorzy:
Żak, Iwona
Niemiec, Paweł
Sarecka, Beata
Balcerzyk, Anna
Ciemniewski, Zbigniew
Rudowska, Ewa
Dyląg, Stanisław
Powiązania:
https://bibliotekanauki.pl/articles/1043632.pdf
Data publikacji:
2003
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
angiotensin converting enzyme gene (ACE)
coronary artery disease
methylenetetrahydrofolate reductase gene (MTHFR)
polymorphisms
Opis:
Angiotensin I-converting enzyme (ACE), which plays an important role in blood pressure regulation, and methylenetetrahydrofolate reductase (MTHFR) involved in homocysteine metabolism belong to a large group of polypeptides which may be potential risk factors for atherosclerosis and coronary artery disease (CAD). To assess whether polymorphisms of the genes encoding these peptides are associated with CAD in Silesian we conducted a study among 68 individuals suffering from CAD (including 52 cases after myocardial infarction), 51 subjects with positive family history of CAD and 111 controls. We analysed the distribution of genotypes and allele frequencies of the insertion/deletion (I/D) polymorphism in the ACE gene using PCR amplification, and the C677→T polymorphism in the MTHFR gene using PCR-RFLP analysis. We found that D allele frequency was significantly higher in CAD patients (61%) than in controls (43%) (P = 0.001, OR = 2.06). The D allele carriers (DD + ID genotypes) were more frequent in the CAD patients (85%) compared to control group (65%) (P = 0.003, OR = 3.14), whereas the familial CAD risk group shows the highest frequency of the ID genotype (57% vs 43% in controls). In contrast, the MTHFR polymorphism does not seem to be associated with the disease. Our data indicate that in Silesian CAD patients the disease is strongly associated with carrier-state of the ACE D allele, but not with the C677→T transition in the MTHFR gene.
Źródło:
Acta Biochimica Polonica; 2003, 50, 2; 527-534
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Desorption/ionization on silicon for small molecules: a promising alternative to MALDI TOF.
Autorzy:
Kraj, Agnieszka
Dylag, Tomasz
Gorecka-Drzazga, Anna
Bargiel, Sylwester
Dziuban, Jan
Silberring, Jerzy
Powiązania:
https://bibliotekanauki.pl/articles/1043452.pdf
Data publikacji:
2003
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
proteomics
porous silicon
catecholamines
peptides
DIOS
mass spectrometry
desorption/ionization
MALDI TOF
Opis:
A method has been developed for laser desorption/ionization of catecholamines from porous silicon. This methodology is particularly attractive for analysis of small molecules. MALDI TOF mass spectrometry, although a very sensitive technique, utilizes matrices that need to be mixed with the sample prior to their analysis. Each matrix produces its own background, particularly in the low-molecular mass region. Therefore, detection and identification of molecules below 400 Da can be difficult. Desorption/ionization of samples deposited on porous silicon does not require addition of a matrix, thus, spectra in the low-molecular mass region can be clearly readable. Here, we describe a method for the analysis of catecholamines. While MALDI TOF is superior for proteomics/peptidomics, desorption/ionization from porous silicon can extend the operating range of a mass spectrometer for studies on metabolomics (small organic molecules and their metabolites, such as chemical neurotransmitters, prostaglandins, steroids, etc.).
Źródło:
Acta Biochimica Polonica; 2003, 50, 3; 783-787
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Fotoinaktywacja jako metoda zwiększająca bezpieczeństwo koncentratów krwinek płytkowych
Fotoinactivation as a method of increasing the safety of platelet concentrates
Autorzy:
Mazur, Anna
Rabenda, Nela
Król, Dorota
Drybańska, Bożena
Dyląg, Stanisław
Powiązania:
https://bibliotekanauki.pl/articles/1038613.pdf
Data publikacji:
2012
Wydawca:
Śląski Uniwersytet Medyczny w Katowicach
Tematy:
koncentraty krwinek płytkowych
inaktywacja
rybofl awina
platelet concentrates
inactivation
ribofl avin
Opis:
Platelet concentrates are the basis for treatment of cancer, haematological diseases and transplantation of stem cells and organs. However, bacterial infections are considered the most common infection occurring 1 for 2000–3000 donations of transfused platelet concentrates. Therefore, it seems to be an important step – an inactivation, which was the method of chemical or photochemical work on viral pathogens, bacterial, parasites in destroying them, or blocking the possibility of replication. The aim of our study was to evaluate the eff ect of ribofl avin, as one of the methods of pathogen inactivation, the quality of platelet concentrates (KKP) using the system to inactivate pathogens Mirasol PRT (Pathogen Reduction Technology). Processing with Mirasol PRT system for Platelets preparations did not cause signifi cant diff erence compared to the blood components are not subjected to pathogen reduction in pH and platelet counts. Using this method, so the hemotherapy inactivation may lead to reduce the risk of transmission of infectious agents, particularly those unmarked in standard qualifi cations for use in blood components and products.
Koncentraty krwinek płytkowych są podstawą w leczeniu nowotworów i chorób hematologicznych oraz w przeszczepianiu komórek macierzystych i narządów litych. Jednakże zakażenia bakteryjne uznawane są za najczęstsze zakażania pojawiające się z częstością 1 na 2000–3000 donacji przetoczonych koncentratów krwinek płytkowych. Dlatego tak ważnym krokiem wydaje się inaktywacja, która jako metoda chemiczna lub fotochemiczna działa na patogeny wirusowe, bakteryjne i pasożyty, niszcząc je lub blokując możliwość replikacji. Celem naszych badań była ocena wpływu rybofl awiny – jednej z metod inaktywacji patogenów – na jakość koncentratów krwinek płytkowych (KKP) przy użyciu systemu do inaktywacji patogenów Mirasol PRT (Pathogen Reduction Technology). Przetwarzanie preparatów płytkowych za pomocą systemu MIRASOL PRT nie spowodowało w nich istotnej różnicy – w porównaniu ze składnikami krwi niepoddanymi redukcji patogenów – w zakresie pH oraz liczby płytek. Wykorzystanie tej metody inaktywacji w krwiolecznictwie może prowadzić do zmniejszenia ryzyka przeniesienia czynników zakaźnych, szczególnie nieoznaczanych w standardowej kwalifi kacji do użytku, w składnikach krwi i produktach krwiopochodnych.
Źródło:
Annales Academiae Medicae Silesiensis; 2012, 66, 1; 24-27
1734-025X
Pojawia się w:
Annales Academiae Medicae Silesiensis
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Innowacyjność a stres, wypalenie i zaangażowanie zawodowe
Innovativeness and stress, burnout and work engagement
Autorzy:
Dyląg, Anna
Łącała, Zofia
Powiązania:
https://bibliotekanauki.pl/articles/595863.pdf
Data publikacji:
2014
Wydawca:
Łódzkie Towarzystwo Naukowe
Tematy:
innowacyjność
stres
wypalenie zawodowe
zaangażowanie zawodowe
innovativeness
stress
burnout
work engagement
Opis:
This study examines potential relationship between Polish respondents’ well-being and innovativeness. Well-being is considered as reported level of stress, burnout and work engagement. Indicators of innovativeness were calculated for each region of Poland. Differences and similarities in innovativeness and well-being between regions, countries and nations, are discussed theoretically and with the help of the questionnaire studies conducted in Malopolska region. The instruments used were: Maslach Burnout Inventory – General Survey / MBI-GS, for measuring burnout (N = 557), and Utrecht Work Engagement Scale / UWES, for measuring work engagement (N = 474). In addition, the most innovative firms of Malopolska region were interviewed with respect to perceived work stress and burnout. It can be concluded that the low level of innovativeness of Polish economy may also be related to the poor level of well-being reported by Polish respondents.
Źródło:
Studia Prawno-Ekonomiczne; 2014, XCII (92); 243-261
0081-6841
Pojawia się w:
Studia Prawno-Ekonomiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Perception of work environment among women and men – workload and autonomy in relation to job engagement
Autorzy:
Jaworek, Magdalena
Dyląg, Anna Maria
Powiązania:
https://bibliotekanauki.pl/articles/685130.pdf
Data publikacji:
2015
Wydawca:
Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego
Tematy:
workload, job control, work engagement
Opis:
This article refers to the phenomenon of employee engagement as one of the key aspects of contemporary human resources management. The concept of professional engagement is a multi-dimensional approach relating to the positively understood effects of work, welfare of on employee, and optimization of the organization and its environment. Job engagement is believed to be strongly related to such processes as introduction of change in organizations, quality and performance issues, customer satisfaction or health, and effectiveness of people and organizations. Following the widely recognized in occupational health psychology model of Karasek (1979) and its further expansions, the authors of this article look upon work engagement as a subjective, psychological state of employees that emerges in certain circumstances, namely a “healthy” work environment. Following Kara-sek’s thinking it was hypothesised that perception of managable workload and sufficient autonomy will lead to the most required effects, such as higher levels of job engagement and its positive consequences.Thus, the specific purpose of this article is to investigate the way employees perceive their work environment in terms of workload and job autonomy in relation to job engagement. The empirical research was conducted from the perspective of the analysis of professional activity depending on the gender of respondents, limitations of social roles and the situation of women in Poland. The authors of the article conducted a questionnaire survey on a sample of 748 economically active persons, both women and men. The analyses showed statistically significantly higher levels of all three examined dimensions of job engagement (i.e. absorption, dedication, vigour) in women compared to men, together with a lower level of control (professional autonomy) declared by women. Control was a clear predictor of work engagement, to a similar extent in both men and women. In contrast, the relationship of workload with absorption, dedication and vigour proved to be variable and dependent on gender.
Źródło:
Jagiellonian Journal of Management; 2015, 1, 3
2450-114X
Pojawia się w:
Jagiellonian Journal of Management
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Work-related factors and age as determinants of three burnout dimensions among Polish hospital nurses
Autorzy:
Jaworek, Magdalena
Dyląg, Anna
Powiązania:
https://bibliotekanauki.pl/articles/685097.pdf
Data publikacji:
2015
Wydawca:
Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego
Tematy:
wypalenie zawodowe, czynniki związane z pracą, wymagania pracy, czynniki stymulujące, pielęgniarki, badanie poprzeczne
Opis:
The aim of the current study was to investigate which of the examined work-related factors was regarded as the most demanded and stimulating in nurses’ job, and which of the age--related factors were the predictors of the three burnout dimensions: emotional exhaustion (EE), depersonalization (DP), and reduced personal accomplishment (rPA). This study was structured as a cross-sectional project, and the data were gathered using ananonymous questionnaires in 4 hospitals in Poland. The sample consisted of 237 nurses. According to the nurses studied, the most strained factors in their job were low salaries and current bad situation of the Polish health service, and the most stimulating– working in the pleasant atmosphere and patients’ satisfaction. The highest score of emotional exhaustion and reduced personal accomplishment were characteristic of nurses above 40 years of age. Burnout syndrome was predicted by socio-organization environment requirements (EE, DP), sensory and mental task requirements (EE), organizational conditions (EE, rPA), job control (DP), social/communication condition (DP, rPA), and age (EE).
Źródło:
Jagiellonian Journal of Management; 2015, 1, 1
2450-114X
Pojawia się w:
Jagiellonian Journal of Management
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-6 z 6

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