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Tytuł:
Characterized Microstructure and Electrical Properties of Hydrogenated Nanocrystalline Silicon Films by Raman and Electrical Conductivity Spectra
Autorzy:
Xiao-Yong, Gao
Jian-Tao, Zhao
Yu-Fen, Liu
Qing-Geng, Lin
Yong-Sheng, Chen
Jin-Hua, Gu
Shi-E, Yang
Jing-Xiao, Lu
Powiązania:
https://bibliotekanauki.pl/articles/1808127.pdf
Data publikacji:
2009-03
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
71.23.Cq
73.61.-r
Opis:
Microstructure and electrical properties of hydrogenated nanocrystalline silicon (nc-Si:H) film deposited on glass substrate at low temperature were characterized by average grain size, crystallinity, and dark electrical conductivity data obtained from the Raman and electrical conductivity spectroscopy, respectively. The average grain size, crystallinity and electrical conductivity have a similar change with substrate temperature. A threshold substrate temperature determined by silane concentration appears in their corresponding spectroscopy vs. substrate temperature. The dependence of crystallinity, average grain size and electrical conductivity on substrate temperature were accounted for by surface diffusion model and heterojunction quantum dot model, respectively.
Źródło:
Acta Physica Polonica A; 2009, 115, 3; 738-741
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Myocardial remodeling in rats with metabolic syndrome: role of Rho-kinase mediated insulin resistance
Autorzy:
Li, Chuan-Bao
Li, Xiao-Xing
Chen, Yu-Guo
Gao, Hai-Qing
Bao, Cheng-Mei
Liu, Xiang-Qun
Bu, Pei-Li
Zhang, Juan
Zhang, Yun
Ji, Xiao-Ping
Powiązania:
https://bibliotekanauki.pl/articles/1039743.pdf
Data publikacji:
2012
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Rat
Metabolism
Myocardium
Phosphorylation
Insulin resistance
Opis:
Insulin resistance (IR) plays a critical role in metabolic syndrome (MS). Previous studies have demonstrated that activated ROCK is increased in MS patients. However, the effect of Rho-kinase (ROCK) on IR has not been definitely determined. Thus, the aims of the present study were to determine whether ROCK activation induces IR or affects myocardial structure and function, as well as the possible mechanisms underlying this process. Wistar rats fed high fat, high glucose and high salt diet sewed as model of MS and we used transmission electron microscopy, echocardiogram technology, and terminal deoxynucleotidyl transferase-mediated DNA nick-end labeling staining to identify any myocardial damage. The protein levels of MYPT-1 (characteristic of ROCK activation), IRS-1 and AKT were analyzed by immunohistochemistry and Western blotting. In hearts from MS rats, we found increased protein levels of phospho-MYPT-1 and phospho-IRS-1 (Ser307) and decreased phospho-AKT compared to levels in normal rats. In conclusion, the results suggest that ROCK-mediated IR is involved in the development of myocardial impairments in MS rats and that this effect is mediated probably via the IRS-1/PI3-kinase/AKT pathway.
Źródło:
Acta Biochimica Polonica; 2012, 59, 2; 249-254
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Vps41, a protein involved in lysosomal trafficking, interacts with caspase-8
Autorzy:
Wang, Lu
Pan, Xiao
He, Liangqiang
Zhang, Rong
Chen, Wei
Zhang, Jing
Lu, Min
Hua, Zi-Chun
Powiązania:
https://bibliotekanauki.pl/articles/1039602.pdf
Data publikacji:
2013
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
caspase-8
yeast two-hybrid
Vps41
protein interaction
apoptosis
Opis:
Caspase-8 is a member of the cysteine-aspartic acid protease (caspase) family which plays a central role in apoptosis and development. We screened caspase-8 interacting proteins from mouse T-cell lymphoma and 7.5-day embryo cDNA libraries by yeast two-hybrid system and obtained eleven positive clones, including Vacuolar protein sorting 41 (Vps41), a protein involved in trafficking of proteins from the late Golgi to the vacuole. The interaction of Vps41 with caspase-8 was confirmed by co-immunoprecipitation (co-IP) and co-localization studies in HEK293T cells. Co-IP experiments also showed that Vps41 binds to the p18 subunit of caspase-8 through its WD40 region and RING-finger motif. Furthermore, we found that overexpression of Vps41 promotes Fas-induced apoptosis in A549 human lung adenocarcinoma cells. The cleavage of caspase-3, a caspase-8 downstream effector, was increased when cells were transfected with Vps41-overexpressing plasmid. Together, these results suggest a novel interaction of caspase-8 with Vps41 and provide a potential role of Vps41 beyond lysosomal trafficking.
Źródło:
Acta Biochimica Polonica; 2013, 60, 1; 37-42
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A novel laccase from fresh fruiting bodies of the wild medicinal mushroom Tricholoma matsutake
Autorzy:
Xu, Lijing
Zhu, Mengjuan
Chen, Xiao
Wang, Hexiang
Zhang, Guoqing
Powiązania:
https://bibliotekanauki.pl/articles/1039125.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Tricholoma matsutake
wild mushroom
isolation
laccase
decolorization
Opis:
The knowledge about biological activities of constituents from medicinal mushrooms belonging to the genus Tricholoma is limited. A 59-kDa laccase has now been purified from fresh fruiting bodies of the mushroom Tricholoma matsutake. The purification protocol entailed ion exchange chromatography on DEAE-cellulose, affinity chromatography on Affi-gel blue gel, ion exchange chromatography on CM-cellulose, affinity chromatography on ConA-Sepharose, and gel filtration by fast protein liquid chromatography on Superdex 75. Of the various affinity and ion exchange chromatographic media employed, the laccase bound only on Con A-Sepharose. The activity of the laccase did not undergo major changes over the temperature range 20-80°C. However, all activity vanished following exposure to 100°C for 10 minutes. The enzyme activity varied only slightly over the pH range 3-5, with the optimal pH of 5, but exhibited a precipitous decline when the pH was increased to 6, and was undetectable at pH 8 and 9. The laccase showed activity in the decolorization of azo dyes without a mediator. Its N-terminal sequence demonstrated only slight resemblance to those of other mushroom laccases. The newly described laccase is distinctive from the previously isolated Tricholoma mushroom laccases in a number of aspects.
Źródło:
Acta Biochimica Polonica; 2015, 62, 1; 35-40
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
An integrated model of production scheduling and maintenance planning under imperfect preventive maintenance
Model zintegrowany harmonogramowania produkcji i planowania obsługi technicznej w ramach niepełnej konserwacji zapobiegawczej
Autorzy:
Chen, X.
Xiao, L.
Zhang, X.
Xiao, W.
Li, J.
Powiązania:
https://bibliotekanauki.pl/articles/301817.pdf
Data publikacji:
2015
Wydawca:
Polska Akademia Nauk. Polskie Naukowo-Techniczne Towarzystwo Eksploatacyjne PAN
Tematy:
aperiodic imperfect preventive maintenance
production scheduling
maintenance planning
immune clonal selection algorithm
total profit
nieokresowa niepełna konserwacja zapobiegawcza
harmonogramowanie produkcji
planowanie konserwacji
algorytm odpornościowej selekcji klonalnej
całkowity zysk
Opis:
For a successful company, machines are always required to work continuously to make more profit in a certain period. However, machines can be unavailable due to the scheduled maintenance activities or unexpected failures. Hence, a model connected production scheduling with maintenance planning for a production line which is composed of multiple machines is developed. Suppose preventive maintenance is imperfect and cannot renew all the machines. Age reduction factor and hazard rate increase factor are introduced to illustrate the imperfect character. Aperiodic preventive maintenance policy is adopted. Replacement as perfect maintenance could restore the machine “as good as new”. When and whether to perform replacement is based on a cost-time rate function which is defined to judge whether or not the preventive maintenance is economical. The objective of the joint model is to maximize the total profit which is composed of production value, production cost, maintenance cost (including the preventive maintenance cost and replacement cost), and tardiness cost (which is related to the job sequence and maintenance activities). To optimize the objective, immune clonal selection algorithm is utilized. The proposed model is validated by a numerical example.
Aby firma mogła działać z powodzeniem i przynosić większe zyski w danym okresie czasu, zainstalowane w niej maszyny muszą pracować w sposób nieprzerwany. Niestety, z powodu planowych działań obsługowych lub nieoczekiwanych awarii, maszyny są czasami wyłączane z produkcji. Dlatego też w niniejszym artykule opracowano model łączący harmonogramowanie produkcji z planowaniem obsługi technicznej dla linii produkcyjnej złożonej z wielu maszyn. W pracy założono, że konserwacja zapobiegawcza jest niepełna i nie prowadzi do odnowy wszystkich maszyn. Aby zilustrować jej niepełny charakter, wprowadzono pojęcia czynnika redukcji wieku oraz czynnika wzrostu wskaźnika zagrożenia. Przyjęto politykę nieokresowej konserwacji zapobiegawczej. Wymiana jako forma pełnej konserwacji pozwala na przywrócenie maszyny do stanu "fabrycznej nowości". Kiedy i czy należy przeprowadzić wymianę zależy od funkcji wskaźnika kosztu w stosunku do czasu, który pozwala ocenić, czy konserwacja zapobiegawcza jest opłacalna. Model zintegrowany ma na celu maksymalizację całkowitego zysku, który jest wypadkową wartości produkcji, kosztów produkcji, kosztów obsługi (w tym kosztów konserwacji zapobiegawczej oraz kosztów wymiany) i kosztów nieterminowego zakończenia zadania (ang. lateness, związanych z kolejnością wykonywanych zadań i czynności obsługowych). Aby zoptymalizować opisany cel, wykorzystano algorytm odpornościowej selekcji klonalnej Proponowany model zweryfikowano na przykładzie liczbowym.
Źródło:
Eksploatacja i Niezawodność; 2015, 17, 1; 70-79
1507-2711
Pojawia się w:
Eksploatacja i Niezawodność
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Complete Diagonalization Calculation of the Optical and EPR Data for the Tetragonal $Cu^{2+}$ Center in $Cu^{2+}$-Doped ZnSe Nanocrystals
Autorzy:
Wu, Xiao-Xuan
Zheng, Wen-Chen
Powiązania:
https://bibliotekanauki.pl/articles/1399131.pdf
Data publikacji:
2015-03
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
76.30.Fc
71.70.Ch
78.40.Fy
75.10.Dg
Opis:
By using the complete diagonalization (of energy matrix) method based on the cluster approach (where the admixture between the d orbitals of $d^{n}$ ion and p orbitals of ligands due to covalence effect is considered), the optical and electron paramagnetic resonance data (three optical band positions and four EPR parameters $g_{∥}$, $g_{⊥}$, $A_{∥}$, $A_{⊥}$) are calculated for the tetragonal $Cu^{2+}$ center in $Cu^{2+}$-doped poly vinyl alcohol (PVA) passivated ZnSe nanocrystals with the defect model of $Cu^{2+}$ in the interstitial octahedral site in ZnSe. The calculated results are near the experimental values. The tetragonal elongation of the $Cu^{2+}$ octahedral cluster in ZnSe nanocrystals is obtained. The results are discussed.
Źródło:
Acta Physica Polonica A; 2015, 127, 3; 795-798
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Research on the Optical and EPR Spectral Data and the Local Structure for the Tetragonal $Nb^{4+}$ Center in Glasses
Autorzy:
Wu, Xiao-Xuan
Yu, Xin-Peng
Zheng, Wen-Chen
Powiązania:
https://bibliotekanauki.pl/articles/1402323.pdf
Data publikacji:
2015-07
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
76.30.He
71.70.Ch
78.40.Pg
78.55.Qr
Opis:
Two optical bands and four EPR (or spin-Hamiltonian) parameters (g factors $g_{∥}$, $g_{⊥}$ and hyperfine structure constants $A_{∥}$, $A_{⊥}$) of the tetragonally-compressed $Nb^{4+}$ octahedral center in glasses are calculated from two methods, the complete diagonalization (of energy matrix) method and the perturbation theory method. Both methods are founded on the two-spin-orbit-parameter model where both the contribution to the spectral data from the spin-orbit parameter of central $d^{n}$ ion and that of ligand ion via covalence effect are considered. The calculated results from both the complete diagonalization (of energy matrix) method and perturbation theory method show reasonable agreement with the experimental values. The signs and possible misprint for the observed hyperfine structure constants $A_{∥}$ and $A_{⊥}$ are suggested, and the local structure of the tetragonal $Nb^{4+}$ center in glasses due to the Jahn-Teller effect is gained from the calculations. The results are discussed.
Źródło:
Acta Physica Polonica A; 2015, 128, 1; 72-75
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A unified calculation of the optical and EPR spectral data for the trigonal Cr³⁺ center in Cr³⁺-doped α-RbAl(SO₄)₂·12H₂O alum crystal
Autorzy:
Li, Xiao-Wu
Mei, Yang
Wei, Cheng-Fu
Zheng, Wen-Chen
Powiązania:
https://bibliotekanauki.pl/articles/1070555.pdf
Data publikacji:
2016-03
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
71.70.Ch
76.30.Fc
78.40.Ha
78.55.Hx
Opis:
The optical band positions and the spin-Hamiltonian parameters (g factors g_{∥}, g_{⊥}, and zero-field splitting parameter D) of alum α-RbAl(SO₄)₂·12H₂O:Cr³⁺ are calculated by diagonalizing the 120× 120 complete energy matrix based on the two-spin-orbit-coupling-parameter model. The model takes into account not only the contributions due to the spin-orbit-coupling parameter of central d^{n} ion in the conventional crystal field theory, but also those due to ligands via covalence effect. The calculation indicates that the fourteen observed spectral data (eleven optical band positions and three spin-Hamiltonian parameters) can be reasonably and uniformly explained with four adjustable parameters (the Racah parameters B, C, intrinsic parameter A̅₄(R) in the superposition model, and the trigonal distortion angle β). The calculations also suggest that contrary to the previous findings, the trigonal distortion of Cr³⁺ (entering the Al³⁺ site in the host crystal) center in α-RbAl(SO₄)₂·12H₂O is induced mainly by the oxygen (or water) octahedron around the Cr³⁺ ion rather than the more distant neighbors.
Źródło:
Acta Physica Polonica A; 2016, 129, 3; 340-343
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Preliminary results of spatial distribution of uranium and thorium in soil profi les near a uranium industrial site, Guangdong province, China
Autorzy:
Wang, J.
Liu, J.
Chen, Y.
Song, G.
Chen, D.
Xiao, T.
Li, H.
Wang, C.
Jiang, F.
Powiązania:
https://bibliotekanauki.pl/articles/146530.pdf
Data publikacji:
2016
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
spatial distribution
thorium
uranium
U/Th ratio
Opis:
Four soil profiles were collected from locations with different distances (5, 50, 250 and 1000 m) from a uranium mill tailings dam, Guangdong province, China, to investigate the pollution status of the soil in mining/ milling-related areas based on the contents of uranium (U) and thorium (Th), thus to understand the impacts of uranium industrial activities to the surroundings. The U and Th concentrations were determined by inductively coupled plasma mass spectrometry (ICP-MS) after conventional HF-HNO3-HClO4 digestion procedures. The results indicate that the soils within 50 m from uranium tailing were severely contaminated; those in 250 and 1000 m soil samples were observed to be with local background level even though these in 250 m had slightly higher U/Th ratios. Uranium concentrations varied from 5.50 ± 0.27 to 160.55 ± 8.03 mg/kg, with maximum values recorded in an intermediate layer of the 5-m distance soil profile. In comparison, the concentration of Th ranged from 6.02 ± 0.30 to 84.71 ± 4.24 mg/kg, with maximum values observed in the top layer of the 1000-m distance soil profile. The U/Th ratio varied from 0.15 to 11.99 compared with 0.20, 0.22 and 0.26 of the average for Guangdong province, national China and the world, respectively. The mean U/Th of four soil profiles showed a reduction with distance from the uranium mill tailing dam, suggesting the relatively large magnitude of uranium elevation in soils within limited distances.
Źródło:
Nukleonika; 2016, 61, 3; 367-371
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Bivariate distribution characteristics of spatial structure in five different Pinus massoniana forests
Autorzy:
Zhang, Ren-bo
Ding, Gui-jie
Luo, Xiao-man
Chen, Mo-fang
Powiązania:
https://bibliotekanauki.pl/articles/956829.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Instytut Dendrologii PAN
Tematy:
uniform angle index
mingling
dominance
structure-based forest management
Opis:
Bivariate distribution is an effective approach to spatial structure analysis. Combined with two of the three structure parameters (uniform angle index (W), dominance (U) and mingling (M)), the structural bivariate characteristics of five different Pinus massoniana forests were explored in this study. Our objective was to provide a theoretical direction for structure-based and detailed management in P. massoniana forests. The bivariate traits showed that mixed artificial or secondary forests predominated by P. massoniana trees do not typically achieve the highest mingling level. Trees under extreme mingling conditions were rare and typically comprised of non-dominant species instead of dominant ones in P. massoniana forests; these trees were generally overtopped and randomly distributed. Management implications can be extracted comparing the bivariate traits between all species and dominant species. The original community structure, development stage, and mixed-tree species number affect the univariate M and, furthermore, the two bivariate U-M and W-M distributions in mixed forests. Forest type has little effect on all-species W-U traits compared to those of the dominant species. U-M traits should be adjusted first if the random frequency values are highest in W-U and W-M bivariate distribution, and it is necessary to determine whether these two bivariate traits shade the W univariate. Adjustments made based on bivariate distribution can reveal poor frequency combinations for foresters to target; this allows the simultaneous adjustment of dual aspects of forest structure based on one bivariate index. Our results show that bivariate distribution may provide very useful information for the management of P. massoniana and other forests.
Źródło:
Dendrobiology; 2017, 78; 75-84
1641-1307
Pojawia się w:
Dendrobiology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Joint optimization of replacement and spare ordering for critical rotary component based on condition signal to date
Wspólna optymalizacja wymiany i zamawiania części zamiennych dla krytycznego komponentu obrotowego na podstawie dotychczasowego sygnału stanu
Autorzy:
Chen, X.
Xu, D.
Xiao, L.
Powiązania:
https://bibliotekanauki.pl/articles/301404.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Polskie Naukowo-Techniczne Towarzystwo Eksploatacyjne PAN
Tematy:
prognozowanie degradacji
degradation prediction
failure probability
condition-based replacement
spare part ordering
prawdopodobieństwo wystąpienia uszkodzenia
wymiana w oparciu o stan
zamawianie części zamiennych
Opis:
It is widely accepted that condition-based replacement can not only make full use of components, but also decline inventory cost if the procurement of spare parts can be triggered upon accurate failure prediction. Most of the existing degradation or failure prediction models and approaches are population-based failures or suspensions, namely, to predict the failure time of a component, there are some failure or suspension histories of same type or similar components which can be used as reference. However, in practice, there exists the phenomenon in which no failure or suspension histories for some components can be used, what can be utilized is just the collected condition monitoring signals to date. In that case, failure time and probability are difficult to be estimated accurately. In this paper, a novel degradation prediction approach is introduced. Meantime, a new failure probability estimation function is developed based on component “service time” and “degradation extent” simultaneously. Then replacement and spare part ordering are jointly optimized according to the estimated failure probability. The optimization objective is to minimize long-run cost rate. Two bearing datasets are used to validate the proposed approach.
Powszechnie przyjmuje się, że wymiana w oparciu o stan techniczny pozwala nie tylko na pełne wykorzystanie elementów składowych, ale także na zmniejszenie kosztów magazynowych (związanych z przechowywaniem zapasów) jeśli zamawianie części zamiennych da się powiązać z trafnym prognozowaniem uszkodzeń. Większość istniejących modeli i teorii predykcji degradacji lub uszkodzeń opiera się na danych populacyjnych o uszkodzeniach lub zawieszeniu pracy co oznacza, że czas uszkodzenia komponentu przewiduje się w odniesieniu do historii uszkodzeń lub zawieszeń pracy tego samego typu lub podobnego typu elementów składowych. Jednak w praktyce zdarza się, że dla niektórych komponentów nie istnieją historie uszkodzeń lub zawieszenia pracy, do których można by się odnieść; jedyne co można wykorzystać to zgromadzone dotychczas sygnały z monitorowania stanu. W takim przypadku, trudno jest ocenić dokładnie czas i prawdopodobieństwo wystąpienia uszkodzenia. W niniejszej pracy, przedstawiono nowatorskie podejście do przewidywania degradacji. Opracowano nową funkcję szacowania prawdopodobieństwa uszkodzenia opartą na jednoczesnym wykorzystaniu "czasu pracy" oraz "stopnia degradacji" komponentu. Następnie wspólnie zoptymalizowano procesy wymiany i zamawiania części zamiennych zgodnie z szacowanym prawdopodobieństwem wystąpienia uszkodzenia. Celem optymalizacji była minimalizacja długoterminowego wskaźnika kosztów . Poprawność proponowanego podejścia zweryfikowano z wykorzystaniem dwóch zbiorów danych dotyczących łożysk.
Źródło:
Eksploatacja i Niezawodność; 2017, 19, 1; 76-85
1507-2711
Pojawia się w:
Eksploatacja i Niezawodność
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The application of E-learning in maritime education and training in China
Autorzy:
Chen, X.
Bai, X.
Xiao, Y.
Powiązania:
https://bibliotekanauki.pl/articles/116574.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Morski w Gdyni. Wydział Nawigacyjny
Tematy:
maritime education and training (MET)
MET System in China
e-Learning
e-Learning training
education system
maritime education
STCW Convention
application of e-Learning
Opis:
E-learning brings the third wave to Internet applications. E-learning is a new training mode with the open characteristics, which is completely different with traditional training. E-learning teaches students the specialized knowledge of theories, work experience and technology by information networks and computer hardware equipment. Students can through a variety of terminal equipment to learn anytime and anywhere, so as to improve student learning results. Maritime education and training must conform to the trend of times to explore E-learning training to improve the training performance. In this paper, based on the theory of E-learning, comparing the advantages and disadvantages of E-learning training. By analyzing current status of maritime education and training, using E-learning to establish China's maritime education and training of the lifelong education system, using E-learning to promote the internationalization of navigation education and training.
Źródło:
TransNav : International Journal on Marine Navigation and Safety of Sea Transportation; 2017, 11, 2; 349-354
2083-6473
2083-6481
Pojawia się w:
TransNav : International Journal on Marine Navigation and Safety of Sea Transportation
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ezetimibe prevents myocardial remodeling in an obese rat model by inhibiting inflammation
Autorzy:
Li, Xiao-Xing
Zhao, Lang
Chang, Ying
Liu, Bao-Shan
Xu, Feng
Zhang, Cheng
Ji, Xiao-Ping
Chen, Yu-Guo
Li, Chuan-Bao
Powiązania:
https://bibliotekanauki.pl/articles/1038380.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
obese
inflammation
remodeling
ezetimibe
IL-6
Opis:
Inflammation plays an important role in the development of many obesity-related diseases. This study aimed to investigate the effect of ezetimibe on inflammation and myocardial remodeling in obese rats. A rat model of obesity was established, and myocardial damage was examined by transmission electron microscopy and Masson staining. Twenty obese rats were divided into two groups (n=10): obese group and ezetimibe group. Ten SD rats were used as controls. Western blot was performed to monitor the expression of P-p38MAPK and interleukin (IL)-6. Immunohistochemical staining was used to monitor the expression of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1. In the obese rats group, we observed increased inflammatory factors and myocardial hypertrophy. In contrast, the ezetimibe group exhibited decreased expression of inflammatory factors and an improvement in myocardial remodeling compared to the obese group. Mechanistically, we found that ezetimibe decreased P-p38MAPK, IL-6, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 levels in the hearts of the obese rats. Taken together, these results indicate that ezetimibe may improve myocardial remodeling in obese rats by inhibiting inflammation.
Źródło:
Acta Biochimica Polonica; 2018, 65, 3; 465-470
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Feasibility study on preparation of magnesium titanate in carbonthermic reduction of vanadium titanomagnetite concentrates
Autorzy:
Chen, Chao
Sun, Ti-Chang
Kou, Jue
Wang, Xiao-Ping
Zhao, Yong-Qiang
Powiązania:
https://bibliotekanauki.pl/articles/110181.pdf
Data publikacji:
2019
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
vanadium titanomagnetite
carbonthermic reduction
magnesium titanate
formation mechanism
Opis:
Effect of temperature and Mg:Ti ratio on phase composition and microstructure of reduced pellets was investigated to verify the feasibility of preparation of magnesium titanate by adding MgO in carbonthermic reduction of the vanadium titanomagnetite concentrates (VTC). Thermodynamic analysis results showed that magnesium titanate is more easily generated than FeTi2O5 or TiO2 by the reaction of FeTiO3 and MgO under the reductive atmosphere, which was confirmed by the discovery of magnesium titanate at roast experiment. It was found that the optimum conditions for reduction of VTC pellets were temperature of 1250 ºC and Mg:Ti ratio of 2, and the main phases of reduction product were metallic Fe and magnesium titanate (Mg2TiO4). However, trace iron impurities in Mg2TiO4 particles were found by energy-dispersive spectroscopy (EDS), so further purification is required.
Źródło:
Physicochemical Problems of Mineral Processing; 2019, 55, 2; 417-425
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The separation of microscale HA in aqueous solution by foam separation technique
Autorzy:
Wenyao, Shao
Xiao, Gong
Shuming, Cui
Ying, Lin
Yinghua, Lu
Yuqing, Chen
Powiązania:
https://bibliotekanauki.pl/articles/949357.pdf
Data publikacji:
2019
Wydawca:
Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
Tematy:
Foam Separation
Hyaluronic Acid
Enrichment Ratio
Recovery Rate
Opis:
Hyaluronic acid (HA) has important applications in fields of health care products, cosmetics and clinical medical. However, the unique physiological properties of HA make cost of its traditional separation and extraction process relatively high. Foam separation technique has simple, gentle and efficient advantages on the separation of substances with surface activity by using bubbles as the separation medium. In this paper, natural surfactant CocamideBetaine (CAPB) was used as a foaming agent to explore the technology of microscale HA in aqueous solution by foam separation. The optimum process conditions were determined based on the recovery rate and enrichment ratio of HA by single factor and orthogonal experiment: at room temperature, pH = 7, separating air velocity (v) = 350 mL/min, HA concentration (CHA) = 50 mg/L, adding liquid volume (V) = 200 mL, collecting time (tcol) = 10 min, CAPB concentration (CCAPB) = 0.035 g/L. Under these conditions, HA enrichment ratio (E) equals 6.821 and HA recovery rate (R) equals 66.425%.
Źródło:
Polish Journal of Chemical Technology; 2019, 21, 4; 66-71
1509-8117
1899-4741
Pojawia się w:
Polish Journal of Chemical Technology
Dostawca treści:
Biblioteka Nauki
Artykuł

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