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    Wyświetlanie 1-14 z 14
    Tytuł:
    Lessons learned from 2001–2021 – from the bioterrorism to the pandemic era
    Autorzy:
    Michalski, A.
    Knap, J.
    Bielawska-Drózd, A.
    Bartoszcze, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/28761885.pdf
    Data publikacji:
    2022
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2022, 29, 1; 1-11
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Microbiological analysis of bioaerosols collected from Hospital Emergency Departments and ambulances
    Autorzy:
    Bielawska-Drózd, A.
    Cieślik, P.
    Bohacz, J.
    Kornillowicz-Kowalska, T.
    Żakowska, D.
    Bartoszcze, M.
    Wlizło-Skowronek, B.
    Winnicka, I.
    Brytan, M.
    Kubiak, L.
    Skopińska-Różewska, E.
    Kocik, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/2081735.pdf
    Data publikacji:
    2018
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    Button Sampler
    bioaerosol
    Hospital Emergency Departments
    ambulances
    bacteria
    fungi
    Opis:
    Introduction and objective. The goal of the study was a microbiological, qualitative and quantitative analysis of bioaerosol at the workplace of medical personnel (Health Emergency Departments (HEDs), ambulances), and comparative administration offices with an expected neutral occupational exposure to biological agents measured with individual Button Sampler. Materials and method. Personal sampling was performed with Button Sampler instrument loaded with gelatine filters in 10 HEDs, in 9 ambulances and in 9 offices to assess the occupational biological agents’ exposure in air. Sampling was conducted from March until April 2016. Samples were quantitatively assessed for viable and total number of bacteria and fungi. Routine procedures for microbiological diagnostics were implemented. Data were analysed using Kruskal–Wallis and Mann-Whitney statistical tests with α=0.05. P value less than 0.05 were considered significant. Results. At the workplaces assessed, the concentrations of viable microorganisms in HEDs were 1.3 × 102 – 4.2 × 103 CFU/m3 for bacteria, 3.4 × 100 – 8.1 × 101 CFU/m3 for fungi; in ambulances 1.3 × 102 – 1.4 × 103 CFU/m3 (bacteria), 6.7 × 100 – 6.5 × 102 CFU/m3 (fungi) and in offices 4.2 × 101 – 5.0 × 103 CFU/m3 (bacteria), 0 – 7.9 × 102 CFU/m3 (fungi). In outdoor air, the number of microorganisms reached the level: 1.0 × 102 – 5.9 × 102 CFU/m3 for bacteria and 1.5 × 102 – 8.2 × 102 CFU/m3 for fungi. The predominant isolated bacteria were Gram-positive cocci. The prevalent fungi species belonged to the genus Aspergillus and Penicillium. Conclusions. The quantitative assessment of examined indoor air was similar to control outdoor air, and were relatively low. The level of microbiological contamination did not exceed 5 × 103 CFU/m3 which is recommended as an admissible level in public spaces in Poland.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2018, 25, 2; 274-279
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Utilisation of peptides against microbial infections – a review
    Autorzy:
    Mirski, T.
    Niemcewicz, M.
    Bartoszcze, M.
    Gryko, R.
    Michalski, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/2081601.pdf
    Data publikacji:
    2018
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    antimicrobial peptides
    infections
    drugs
    therapy
    Opis:
    The emergence of resistance in microorganisms on a global scale has made it necessary to search for new antimicrobial factors. Antimicrobial peptides (AMPs) seem to meet these expectations. AMPs are produced by bacteria, viruses, plants, and animals, and may be considered as a new class of drugs intended for the prophylaxis and treatment of both systemic and topical infections. The aim of this study is to review the results of studies on the use of peptides to combat infections in vivo. Antimicrobial peptides may be applied topically and systemically. Among the peptides used topically, a very important area for their application is ophthalmology. AMPs in ophthalmology may be used mainly for the protection of contact lenses from ocular pathogens. Many AMPs are in clinical trials for application in the therapy of local infections. There may be mentioned such preparations as: pexiganan (magainin analogue), MX-226 (based on indolicidin), NEUPREX (isolated from human BPI (bactericidal/permeability-increasing) protein), IB-367 (variant of porcine protegrin), P113 (based on histatin), daptomycin, polymyxins, as well as peptidomimetics. In the combat against systemic infections are used such peptides as: P113D (modified P113 peptide containing D-amino acids), colistin, peptoids, and peptides containing non-typical amino acids or non-peptide elements. AMPs are also used as antiprotozoal, antifungal, antitoxic and immunostimulatory agents. The limitations in the use of peptides in the treatment of infections, such as susceptibility to proteolysis, and resistance of microorganisms to the peptides, are also discussed. AMPs are a promising strategy in the fight against microbial infections.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2018, 25, 2; 205-210
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Microarrays - new possibilities for detecting biological factors hazardous for humans and animals, and for use in environmental protection
    Autorzy:
    Mirski, T.
    Bartoszcze, M.
    Bielawska-Drozd, A.
    Gryko, R.
    Kocik, J.
    Niemcewicz, M.
    Chomiczewski, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/51516.pdf
    Data publikacji:
    2016
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2016, 23, 1
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Bacillus anthracis infections – new possibilities of treatment
    Autorzy:
    Zakowska, D.
    Bartoszcze, M.
    Niemcewicz, M.
    Bielawska-Drozd, A.
    Knap, J.
    Cieslik, P.
    Chomiczewski, K.
    Kocik, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/51666.pdf
    Data publikacji:
    2015
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2015, 22, 2
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Review of methods used for identification of biothreat agents in environmental protection and human health aspects
    Autorzy:
    Mirski, T.
    Bartoszcze, M.
    Bielawska-Drozd, A.
    Cieslik, P.
    Michalski, A.J.
    Niemcewicz, M.
    Kocik, J.
    Chomiczewski, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/51351.pdf
    Data publikacji:
    2014
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2014, 21, 2
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Q fever - selected issues
    Autorzy:
    Bielawska-Drozd, A.
    Cieslik, P.
    Mirski, T.
    Bartoszcze, M.
    Knap, J.P.
    Gawel, J.
    Zakowska, D.
    Powiązania:
    https://bibliotekanauki.pl/articles/49820.pdf
    Data publikacji:
    2013
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    Q fever
    animal species
    man
    Coxiella burnetii
    intracellular parasite
    parasite
    htpAB gene
    IS1111 gene
    genome
    plasmid
    pathomechanism
    infection
    bioterrorism
    epidemiology
    epizootiology
    treatment
    prophylaxis
    laboratory diagnostics
    serological method
    molecular diagnostics
    Opis:
    Q fever is an infectious disease of humans and animals caused by Gram-negative coccobacillus Coxiella burnetii, belonging to the Legionellales order, Coxiellaceae family. The presented study compares selected features of the bacteria genome, including chromosome and plasmids QpH1, QpRS, QpDG and QpDV. The pathomechanism of infection – starting from internalization of the bacteria to its release from infected cell are thoroughly described. The drugs of choice for the treatment of acute Q fever are tetracyclines, macrolides and quinolones. Some other antimicrobials are also active against C. burnetii, namely, telitromycines and tigecyclines (glicylcycline). Q-VAX vaccine induces strong and long-term immunity in humans. Coxevac vaccine for goat and sheep can reduce the number of infections and abortions, as well as decrease the environmental transmission of the pathogen. Using the microarrays technique, about 50 proteins has been identified which could be used in the future for the production of vaccine against Q fever. The routine method of C. burnetii culture is proliferation within cell lines; however, an artificial culture medium has recently been developed. The growth of bacteria in a reduced oxygen (2.5%) atmosphere was obtained after just 6 days. In serology, using the IF method as positive titers, the IgM antibody level >1:64 and IgG antibody level >1:256 (against II phase antigens) has been considered. In molecular diagnostics of C. burnetii infection, the most frequently used method is PCR and its modifications; namely, nested PCR and real time PCR which detect target sequences, such as htpAB and IS1111, chromosome genes (com1), genes specific for different types of plasmids and transposase genes. Although Q fever was diagnosed in Poland in 1956, the data about the occurrence of the disease are incomplete. Comprehensive studies on the current status of Q fever in Poland, with special focus on pathogen reservoirs and vectors, the sources of infection and molecular characteristics of bacteria should be conducted.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2013, 20, 2
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Research on substances with activity against orthopoxviruses
    Autorzy:
    Kolodziej, M.
    Joniec, J.
    Bartoszcze, M.
    Gryko, R.
    Kocik, J.
    Knap, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/51870.pdf
    Data publikacji:
    2013
    Wydawca:
    Instytut Medycyny Wsi
    Opis:
    Although smallpox was eradicated over 30 years ago, the disease remains a major threat. High mortality, high infectivity and low resistance of the contemporary population make the smallpox virus very attractive to terrorists. The possible presence of illegal stocks of the virus or risk of deliberate genetic modifications cause serious concerns among experts. Hence, it is reasonable to seek effective drugs that could be used in case of smallpox outbreak. This paper reviews studies on compounds with proven in vitro or in vivo antipoxviruses potential, which show various mechanisms of action. Nucleoside analogues, such as cidofovir, can inhibit virus replication. Cidofovir derivatives are developed to improve the bioavailability of the drug. Among the nucleoside analogues under current investigation are: ANO (adenozine N1-oxide) and its derivatives, N-methanocarbothymidine [(N)-MCT], or derivatitives of aciklovir, peninclovir and brivudin. Recently, ST-246 – which effectively inhibits infection by limiting release of progeny virions – has become an object of attention. It has been also been demonstrated that compounds such as: nigericin, aptamers and peptides may have antiviral potential. An interesting strategy to fight infections was presented in experiments aimed at defining the role of individual genes (E3L, K3L or C6L) in the pathogenesis, and looking for their potential blockers. Additionally, among substances considered to be effective in the treatment of smallpox cases, there are factors that can block viral inhibitors of the human complement system, epidermal growth factor inhibitors or immunomodulators. Further studies on compounds with activity against poxviruses are necessary in order to broaden the pool of available means that could be used in the case of a new outbreak of smallpox.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2013, 20, 1
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Research on prevention and treatment of hemorrhagic fevers
    Autorzy:
    Joniec, J.
    Kolodziej, M.
    Bartoszcze, M.
    Kocik, J.
    Knap, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/52164.pdf
    Data publikacji:
    2012
    Wydawca:
    Instytut Medycyny Wsi
    Opis:
    Viral hemorrhagic fevers are severe zoonotic diseases caused by RNA-viruses classified into 4 families: Arenaviridae, Bunyaviridae, Filoviridae, and Flaviviridae. They are present on all continents except Antarctica, their person-to-person spread is easy, and there is a high risk of them being used as weapon by bioterrorists. So far, efforts to develop effective drugs against these viruses have failed, and typical therapy usually relies on symptomatic treatment. Search for substances that could effectively inhibit this type of infections is now a priority. The presented paper gives an overview of different approaches used in combating the viral hemorrhagic fevers. Researchers look for safe antiviral agents with appropriate properties among natural sources, such as various types of herbs plants, algae, or essential oils obtained from trees, as well as investigate the use of various synthetic substances. The aim is to broaden the pool of available antiviral drugs that could replace hitherto applied medicines such as ribavirin, which is not always sufficiently effective and may have side-effects. The scientists focus not only on combating the diseases, but also on their prevention. For this purpose, recombinant vaccines or various types of immunomodulators may serve as a useful tools. Results of the latest studies are promising and encourage further work which may eventually lead to the solution of the urgent problem of hemorrhagic fevers.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2012, 19, 2
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Przeżywalność Campylobacter jejuni w wodzie z dodatkiem
    The survival of Campylobacter jejuni in water with addend potassium nitrate
    Perzhivanie Campylobacter jejuni v vode s dobavkojj azotnokislogo kalija
    Autorzy:
    Bartoszcze, M.
    Dabrowski, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/874345.pdf
    Data publikacji:
    1987
    Wydawca:
    Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
    Tematy:
    campylobacter
    campylobacter jejuni
    azotany
    azotan potasu
    szczepy
    Źródło:
    Roczniki Państwowego Zakładu Higieny; 1987, 38, 4-5
    0035-7715
    Pojawia się w:
    Roczniki Państwowego Zakładu Higieny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Wpływ NaCl na przeżywalność campylobacter jejuni w temperaturze -20 C
    Sodium chloride effect on the survival of campylobacter jejuni at -20 C
    Vlijanie NaCl na perezhivanie sampulovaster jejuni v temperature -20 C
    Autorzy:
    Bartoszcze, M.
    Dabrowski, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/875367.pdf
    Data publikacji:
    1987
    Wydawca:
    Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
    Tematy:
    campylobacter jejuni
    przezywalnosc
    mrozy
    zapalenie jelit
    bakterie chorobotworcze
    Źródło:
    Roczniki Państwowego Zakładu Higieny; 1987, 38, 4-5
    0035-7715
    Pojawia się w:
    Roczniki Państwowego Zakładu Higieny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-14 z 14

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