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Tytuł:
Géographie conflictuelle d’une ville : Rue Saint-Urbain de Mordecai Richler et Côte-des-Nègres de Mauricio Segura
Autorzy:
Żurawska, Anna
Powiązania:
https://bibliotekanauki.pl/articles/445140.pdf
Data publikacji:
2013
Wydawca:
Polskie Towarzystwo Badań Kanadyjskich
Opis:
The aim of the article is to examine Rue Saint-Urbain (The Street) by Mordecai Richler and Côte-des-Nègres by Mauricio Segura. Despite numerous differences between the two writers (their origins, languages of their literary expression, time of their artistic activity, etc.), their works share certain characteristics. The narrators of both novels are similar to each other in their sensitivity to the multicultural situation of their quarters, which may be regarded as a source of conflicts and absurdities. The comparative analysis of the two novels, focusing particularly on the literary visions of Montreal presented in both texts, explores the relationships not only between Quebeckers and immigrants, but also between various ethnic groups within the Quebecois metropolis.
Źródło:
TransCanadiana; 2013, 6; 143-156
1899-0355
Pojawia się w:
TransCanadiana
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
L’errance de l’artiste dans La Montagne secrète de Gabrielle Roy
The vagabondage of the artist in The Hidden Mountain by Gabrielle Roy
Autorzy:
Żurawska, Anna
Powiązania:
https://bibliotekanauki.pl/articles/483576.pdf
Data publikacji:
2014
Wydawca:
Katolicki Uniwersytet Lubelski Jana Pawła II. Wydawnictwo Werset
Tematy:
symbolic
existential and artistic wandering
search for the artistic ideal
concept of art
artistic creation
Opis:
The aim of the article is to examine the figure of a vagabond and an artist in the novel The Hidden Mountain (La Montagne secrète) by Gabrielle Roy which, according to Antoine Boisclair, is the first Quebec novel completely devoted to painting. It presents the wandering of the artist who does not perceive his vagabondage as movement from one place to another, but regards it as the essence of both his existence and his creation. First, the analysis explores the problem of wandering as narrative basis, examining the tension between the external reality and the inner experience of the painter. Then, the aim of the artist’s journey, symbolically delineated by the Hidden Mountain, is analyzed. The final part of the article is devoted to the concept of art presented in the novel, with particular emphasis on the humanistic dimension of artistic creation.
Źródło:
Quêtes littéraires; 2014, 4; 103-110
2084-8099
2657-487X
Pojawia się w:
Quêtes littéraires
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
L’image de la mort ou l’histoire d’une sensibilité. Charlotte de David Foenkinos
The image of death or the story of a sensibility. Charlotte by David Foenkinos
Autorzy:
Żurawska, Anna
Powiązania:
https://bibliotekanauki.pl/articles/483750.pdf
Data publikacji:
2015
Wydawca:
Katolicki Uniwersytet Lubelski Jana Pawła II. Wydawnictwo Werset
Tematy:
Charlotte Salomon
the artist
the Künstlerroman
the death
Opis:
The aim of the article is to examine the figure of an artist in the novel Charlotte by David Foenkinos. With his text, he desires to pay homage to Charlotte Salomon, a Jewish painter murdered at age twenty-six in Auschwitz. The Salomon’s biography and works became famous thanks to the novel by Foenkinos. The great merit of his book is to make the painter recognizable to a wide public. The interpretation of the text in which central figure is a painter should include a question about the generic status of the novel, thus the reflection about the Künstlerroman, and about the status of the image in the text, the narrative processes used to make the text more plastic, the ekphrasis, etc. The problem seems interesting because Charlotte does not correspond with the traditional definition of the Künstlerroman. The narrator refers the reader to the extradégétique reality in order to make a connection between the reader and Charlotte’s painting; therefore, he focuses his story on the conception of the image and not on the image itself.
Źródło:
Quêtes littéraires; 2015, 5; 213-221
2084-8099
2657-487X
Pojawia się w:
Quêtes littéraires
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Du mépris à la dignité : Bakhita de Véronique Olmi
Autorzy:
Żurawska, Anna
Powiązania:
https://bibliotekanauki.pl/articles/1912407.pdf
Data publikacji:
2020-12-30
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Tematy:
Bakhita
esclavage
mépris
plénitude
dignité
la beauté intérieure
sécularisation
slavery
disdain
the place of fullness
dignity
inner beauty
secularization
Opis:
Le roman de Véronique Olmi, Bakhita (2017) retrace l’histoire de sainte Joséphine Bakhita en démontrant le processus qui va du mépris, de l’humiliation, de l’animalisation à l’acquisition de la dignité, voire à la sainteté. Le texte met l’accent non pas sur la dégradation des sentiments et de l’être humain, mais il montre comment dépasser les limites imposées par le mépris des autres et atteindre la plénitude. L’objectif du présent article sera, dans un premier temps, d’étudier des manifestations du mépris et des moyens littéraires qui permettent de l’exprimer. Dans un deuxième temps, l’analyse se centrera sur le processus qui va du mépris vers la plénitude, dans l’acception que lui donne Charles Taylor. Enfin, il sera aussi intéressant de poser la question sur les raisons du succès de ce roman « hagiographique » en France laïque.
Véronique Olmi’s novel entitled Bakhita (2017), telling the story of St. Josephine Bakhita, shows the process of achieving dignity, or even sanctity, through overcoming disdain, humiliation, and animalization. However, it is not the degradation of feelings and a human being that is emphasized in Olmi’s novel but the possibility of overcoming the condition of a disdained person in order to enjoy freedom and fullness. The aim of the article is therefore to explore the manifestations of disdain in the analyzed text and the use of rhetorical devices applied to express contempt. The article also examines the process leading from disdain to fullness as defined by Charles Taylor, as well as the reasons for the popularity of the novel in France, regarded as the most laic country in Europe.
Źródło:
Acta Universitatis Lodziensis. Folia Litteraria Romanica; 2020, 15; 253-264
1505-9065
2449-8831
Pojawia się w:
Acta Universitatis Lodziensis. Folia Litteraria Romanica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
La mort à l’haïtienne et la parole rituelle Hadriana dans tous mes rêves de René Depestre
Autorzy:
Żurawska, Anna
Powiązania:
https://bibliotekanauki.pl/articles/700867.pdf
Data publikacji:
2014
Wydawca:
Wydawnictwo Uniwersytetu Śląskiego
Opis:
The aim of the article is to explore the role of selected rituals in the novel Hadriana dans tous mes rêves by René Depestre. The narration is focused on the zombification of the eponymous character on her wedding day and the sudden disappearance of her tomb after the funeral ceremony. Both rituals not only illustrate the social system of Haiti, but also reflect the particular relation between the narrator living in exile (like the author of the book) and his native island personified by Hadriana. First, the novel is analyzed from the anthropological perspective; then, the metaphorical dimension of the rituals described in the book is stressed. Finally, the ritual, possessing some degree of inherent agency, is presented as a symbolic act of performative utterance. Key words: ritual, voodoo and Christian anthropology, marvelous realism (réalisme merveilleux), performative utterance
Źródło:
Romanica Silesiana; 2014, 9
1898-2433
2353-9887
Pojawia się w:
Romanica Silesiana
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
L’image postcoloniale de l’Amérique du Sud dans Saltimbanques, Kaléidoscope brisé et Le Magicien de Sergio Kokis
Autorzy:
Żurawska, Anna
Powiązania:
https://bibliotekanauki.pl/articles/700929.pdf
Data publikacji:
2011
Wydawca:
Wydawnictwo Uniwersytetu Śląskiego
Opis:
This paper attempts to examine the postcolonial image of South America in the trilogy by Sergio Kokis, composed of Saltimbanques, Kaléidoscope brisé and Le Magicien. The three novels focus on adventures of the Circus Alberti which leaves Europe, ravaged by the Second World War, in order to find a better life in South America. A travelling company of performers covers the route of the first colonizers. The journey of the circus artists allows Kokis to unmask political and social consequences of the colonization of South America, such as slavery in the plantations of yerba maté, the poverty of indigenous populations, the authoritarian power of generalissimos, the policy of terror and tortures, fratricidal conflicts, etc. The aim of the article is also to investigate a very complicated relationship between the colonizers and the colonized presented in the three novels. Key words: Journey, cultural imperialism, colonizer/colonized relationship.
Źródło:
Romanica Silesiana; 2011, 6
1898-2433
2353-9887
Pojawia się w:
Romanica Silesiana
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
L’Atlantide ou la quête de l’absence D’un pays sans amour de Gilles Rozier
Autorzy:
Żurawska, Anna
Powiązania:
https://bibliotekanauki.pl/articles/701252.pdf
Data publikacji:
2015
Wydawca:
Wydawnictwo Uniwersytetu Śląskiego
Opis:
The novel D’un pays sans amour (2011) by Gilles Rozier features two narrators who try to recapture the past and to reconstruct with letters the Yiddishland annihilated after World War II. This vanished state, with its cultural capital situated in Warsaw, is called Atlantis in the novel and presented as a paradise in the yiddish literature and language. The choice of this metaphor encourages the reflection on the ambivalence between reality and fiction, as well as on the oppositions between presence and absence or memory and oblivion. What is more, this metaphor refers to the categories of time and space. The aim of this article is to examine the function of the Atlantis metaphor on which the novel is based and to analyze the mechanisms of narrative as memorial (on the basis of Paul Ricœur’s concept) which allow the narrator to rebuild the annihilated world of the mythical island and to bring the non‑existent back into existence. Key words: Atlantis, mythical island, the yiddish literature and language, presence / absence, memory / oblivion, time and space
Źródło:
Romanica Silesiana; 2015, 10
1898-2433
2353-9887
Pojawia się w:
Romanica Silesiana
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Le rôle de l’espace dans la littérature acadienne contemporaine Chacal, mon frère (2010) et L’Ombre de Chacal (2016) de Gracia Couturier
The role of space in contemporary Acadian literature – Gracia Couturier’s Chacal, mon frère (2010) and L’Ombre de Chacal (2016)
Autorzy:
Żurawska, Anna
Powiązania:
https://bibliotekanauki.pl/articles/1053752.pdf
Data publikacji:
2020-12-28
Wydawca:
Wydawnictwo Uniwersytetu Śląskiego
Tematy:
space
identity
Acadian literature
Gracia Couturier
Opis:
The aim of deportation and expulsion of the Acadians during the so-called Grand Dérangement, also known as the Great Upheaval, was to deprive them of their land, which is presented in their history and literature. The idea of space is in this case closely connected with the question of identity in Acadian literature. Not referring directly to the above-mentioned historical events, Garcia Couturier explores in her novelistic diptych the relation between identity and space. Although Couturier’s writing is largely based on categories which characterise Acadian literature, she is able to go beyond them in order to concentrate on individual identity and liberty. She also investigates metaphorical expulsion, which shows her desire for autonomy from tradition and underlines modern aspects of the two novels.The aim of the article is therefore to examine the narrative representation of the space, its symbolic function and its role in shaping both individual and collective identity in Couturier’s novels.
Źródło:
Romanica Silesiana; 2020, 18, 2; 98-107
1898-2433
2353-9887
Pojawia się w:
Romanica Silesiana
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Metody i techniki psychoterapeutyczne wykorzystujące autodystansowanie
Psychotherapeutic methods and techniques using a self-distanced perspective
Autorzy:
Tylikowska, Anna
Żurawska-Żyła, Renata
Powiązania:
https://bibliotekanauki.pl/articles/468091.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Pedagogiczny im. Komisji Edukacji Narodowej w Krakowie
Tematy:
autodystansowanie
dystans psychologiczny
metody psychoterapeutyczne
techniki psychoterapeutyczne
psychoterapia poznawczo-behawioralna
Opis:
Autodystansowanie jest przyjmowaniem szczególnej perspektywy wobec własnych doświadczeń, umożliwiającej człowiekowi obserwowanie ich „z odległości”, czy też z pozycji „muchy na ścianie”. Coraz liczniejsze badania wykazują, że zdystansowane spostrzeganie własnych myśli i emocji, przeciwstawiane „zanurzaniu się” w nich, ma pozytywne skutki poznawcze, emocjonalne i behawioralne –pozwala na rekonstruowanie niefunkcjonalnych schematów poznawczych oraz obniżanie reaktywności emocjonalnej, umożliwiające podejmowanie bardziej adaptacyjnych zachowań. Artykuł prezentuje całościowe metody oraz konkretne techniki psychoterapeutyczne aktywizujące autodystansowanie: terapię ustalonej roli, dramaterapię, technikę dwóch krzeseł, terapię narracyjną, terapie oparte na uważności oraz terapię metapoznawczą. Potwierdzona skuteczność niektórych metod itechnik opartych na uzyskiwaniu i utrwalaniu dystansu wobec własnych doświadczeń może stanowić inspirację do empirycznegotestowania tych, które nie zostały jeszcze przebadane, oraz do tworzenia i testowania nowych.
Self-distancing occurs when aperson adopts the perspective of observing her or his experiences “from adistance” or from the position of “afly on the wall”. Agrowing body of empirical evidence suggests that adopting aself-distanced perspective, opposed to the self-immersed perspective, results in positive cognitive, emotional, and interpersonal outcomes, allowing the reconstruction ofdysfunctional cognitive schemas, the lowering of emotional reactivity, and leads to more adaptive behaviours. The article presents comprehensive methods and specific psychotherapeutic techniques activating self-distancing: fixed-roletherapy, drama therapy, two-chairs technique, narrative therapy, mindfulness-based therapies, and metacognitive therapy. The asserted effectiveness of some of these methods and techniques based on selfdistancing may inspire others to test the methods, whose efficacy have not yet been proven, and to develop and verify new ones.
Źródło:
Annales Universitatis Paedagogicae Cracoviensis. Studia Psychologica; 2017, 10; 77-93
2084-5596
Pojawia się w:
Annales Universitatis Paedagogicae Cracoviensis. Studia Psychologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Poznawczo-emocjonalne i interpersonalne skutki autodystansowania
The cognitive-emotional and interpersonal consequences of self-distancing mechanisms
Autorzy:
Żurawska-Żyła, Renata
Tylikowska, Anna
Powiązania:
https://bibliotekanauki.pl/articles/468115.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Pedagogiczny im. Komisji Edukacji Narodowej w Krakowie
Tematy:
autodystansowanie
dystans psychologiczny
adaptacyjne formy refleksji
regulacja emocji
radzenie sobie
Opis:
Ludzie stosują różne strategie poznawczo-emocjonalne, kiedy konfrontują się z trudnymi doświadczeniami wcelu poradzenia sobie znimi. Liczne badania prowadzone wnurcie społeczno-poznawczym dostarczają przekonujących danych na temat istotnego znaczenia autodystansowania wregulacji emocjonalnej, radzeniu sobie zbolesnymi przeżyciami oraz wutrzymywaniusatysfakcjonujących relacji zinnymi. Stosowanie perspektywy obserwatora opartej na dystansie do siebie (self-distanced perspective) jako formy autorefleksji, wodróżnieniu od perspektywy „zanurzenia wsobie” (self-immersed perspective), przynosi pozytywne skutki poznawcze, emocjonalne i behawioralne dla funkcjonowania osoby wjej wymiarze intrapersonalnym (pozwala na rekonstruowanie dysfunkcjonalnych schematów poznawczych, obniża reaktywność emocjonalną, sprzyjając regulacji emocji ipodejmowaniu adaptacyjnych zachowań) oraz interpersonalnym (jest predyktorem zachowań nakierowanych na rozwiązanie problemu, pomaga radzić sobie z odczuwaną złością i hamować agresję podczas konfliktów z innymi).
People use different cognitive-emotional strategies as coping mechanisms when faced with difficult experiences. Numerous studies conducted in the socio-cognitive field, provide convincing data on the importance of self-distancing in emotional regulation, coping with painful experiences, and maintaining good relations with others. The use of the self-distanced perspective, as a form of self-reflection (opposite to the self-immersed perspective), has apositive cognitive, emotional, and behavioural effect on aperson’s functioning in their intra-personal dimension (it allows them to reduce the level of emotional reactivity, promotes emotional regulation, and adaptive behaviour), as well as their interpersonal dimension (it is apredicator for problem-solving behaviour, atool helping to cope with anger and reducing aggression during conflicts with others).
Źródło:
Annales Universitatis Paedagogicae Cracoviensis. Studia Psychologica; 2017, 10; 77-93
2084-5596
Pojawia się w:
Annales Universitatis Paedagogicae Cracoviensis. Studia Psychologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Quercetin influences BSA alpha-helical structures of native, ACR- and NaNO2-modified BSAs
Autorzy:
Rorbach-Dolata, Anna
Żurawska-Płaksej, Ewa
Piwowar, Agnieszka
Powiązania:
https://bibliotekanauki.pl/articles/895290.pdf
Data publikacji:
2018-12-31
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
albumin
quercetin
nitrosylation
alkylation
conformational changes
circular dichroism
Opis:
Quercetin (QUE) is a plant flavonoid with a multifarious spectrum of properties. It is a prominent component of the human diet, considered to be safe and beneficial for human health. Acrylamide (ACR) and sodium nitrate III (NaNO2) are also present in the diet and may demonstrate adverse and toxic effects on the macromolecules and tissues of the human organism. Albumin, the most abundant blood protein, is the most susceptible to the action of various exogenous factors, which may lead to structural damage and functional disturbances. The aim of this study was to estimate ACR- and NaNO2-induced changes in the secondary structure of bovine serum albumin (BSA), using circular dichroism (CD), and to determine the impact of quercetin on these modifications. BSA was incubated with ACR and NaNO2 solutions in the absence and presence of QUE in two different concentrations (3 mM and 500 µM), and changes in albumin alpha-helical structure were determined by CD. BSA secondary structure was vulnerable to alterations upon treatment with acrylamide and NaNO2, as well as quercetin. QUE, depending on concentration and incubation time, caused a decrease of around 13-19% in the alpha-helix content of BSA molecules, but also prevented the changes in the protein alpha-helical structure initiated by ACR and NaNO2. The most spectacular inhibition was revealed for QUE in lower concentrations after 24h of incubation with NaNO2. Although QUE reveals protective effect towards albumin modifications, it is difficult to unambiguously define whether this effect is advantageous, because quercetin itself causes alterations in BSA structure.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 6; 1339-1346
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Możliwości analiz GMO w świetle obowiązującego prawa oraz rola laboratoriów referencyjnych ds. GMO w Polsce
Law requirements for GMO analysis and the role of GMO reference laboratories in Poland
Autorzy:
Sowa, Sławomir
Linkiewicz, Anna
Żurawska, Magdalena
Grelewska, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/1197737.pdf
Data publikacji:
2007
Wydawca:
Polskie Towarzystwo Przyrodników im. Kopernika
Opis:
Genetically modified organisms are commonly used for scientific and practical purposes. Genetically modified crops have been cultivated worldwide including EU (102 mln ha total in 2006). The use of GMO is regulated by the Directive 90/219 on contained use, Directive 2001/2003 on deliberate release to the environment, Regulation 1829/2003 on genetically modified food and feed, Regulation 1830/2003 on traceability and labeling, and the Polish GMO Law act from 2001. The regulation on food and feed implements a threshold of 0.9% GMO for product labeling. This threshold, however, can be applied to unintended or technically unavoidable GMO presence and corresponds to single ingredient only. Genetically modified organisms can be detected using DNA (PCR) or protein (ELISA) based methods. PCR screening for commonly used DNA fragments (35S promoter or Nos terminator) can be broadly applied, however the proper interpretation of the results requires good knowledge of different GMO constitution. Event specific is the most accurate PCR method for GMO identification. Quantification of GMO in products is done using a RealTime PCR. All analytical methods developed for GMO identification and quantification have to be validated before GMO approval. Validation is performed by the Community Reference Laboratory (CRL) in collaboration with National Reference Laboratories. According to Polish GMO Law the Minister of Environment is responsible for GMO control in Poland that is performed by national competent authorities (eg. Sanitary Inspection, Veterinary Inspection, Seed Inspection).
Źródło:
Kosmos; 2007, 56, 3-4; 237-245
0023-4249
Pojawia się w:
Kosmos
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sexual activity of Subcarpathia residents
Autorzy:
Kremska, Anna
Wróbel, Romana
Pieniążek, Anna
Cecuła, Monika
Żurawska, Justyna
Kołodziej, Bernadeta
Powiązania:
https://bibliotekanauki.pl/articles/454708.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
sexual initiation
condom
sexual relations
Opis:
Introduction. Sexuality is an inseparable attribute of humans that makes it possible to take new challenges connected with it at every stage of life and to enjoy its new aspects as well as to accept the resulting restrictions. Aim. The objective of this study was to compare how sexual activity changes in different age groups. An important step in achieving the main objective was to determine the age of sexual initiation, the number of sexual partners and the most commonly used methods of preventing pregnancy. Material and methods. The study was conducted between 2010 and 2013 among 924 persons. The respondents were the students of secondary schools, technical schools, post-secondary schools and the University of Rzeszów. Results. Two-thirds of a group aged 16-18 did not start sexual relations. Only 2% of the respondents at the age groups of 16- 18,19-23 and only 1% of the respondents at the age group of 24-48 began having sexual relations under the age of 15. 67% of adolescents from big cities began sexual relations. 33% of the secondary schools/technical schools respondents, 51% of the post-secondary schools respondents, 35% of a higher education institution respondents most commonly use condoms as a method of contraception. Conclusions. The average age of sexual initiation is gradually decreasing in each age group. Most respondents declare having one sexual partner. The respondents from big cities more often begin sexual relations. Condoms are the most commonly used method of contraception among the respodents in all age groups.
Źródło:
European Journal of Clinical and Experimental Medicine; 2017, 3; 240-248
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
In vivo and ex vivo impact of nutritional xenobiotics – acrylamide and sodium nitrates – on plasma antioxidant properties
Wpływ wybranych ksenobiotyków pokarmowych – akrylamidu i azotanów – na właściwości antyoksydacyjne osocza w warunkach in vivo oraz ex vivo
Autorzy:
Rorbach-Dolata, Anna
Żurawska-Płaksej, Ewa
Marchewka, Zofia
Piwowar, Agnieszka
Powiązania:
https://bibliotekanauki.pl/articles/1035369.pdf
Data publikacji:
2019
Wydawca:
Śląski Uniwersytet Medyczny w Katowicach
Tematy:
acrylamide
sodium nitrate (iii) and (v)
daily intake
thiol groups
antioxidant potential
akrylamid
azotan (iii) i (v) sodu
dzienne spożycie
grupy tiolowe
potencjał antyoksydacyjny
Opis:
INTRODUCTION: The thiol (SH) groups present in human blood plasma play an important role in the oxidative/antioxidative homeostasis of the organism. They are susceptible to the adverse actions of different exo- and endogenous factors. Chronic exposure to different xenobiotics, e.g. nitrogen-containing compounds commonly occurring in food, is especially important. The aim of this study was to investigate the effect of acrylamide (ACR) and sodium nitrates (SN) – (V) and (III) – on the plasma antioxidant properties, as reflected by changes in the SH group levels. MATERIAL AND METHODS: The concentration of SH groups was measured by Ellman’s method in blood plasma derived from 62 young people (in vivo model; time t0), and after 1 hour of blood plasma incubation with appropriate ACR and SN (III) concentrations (ex vivo model; time t1). The concentrations used corresponded with their daily intake (DIA – daily intake of acrylamide, and DIN – daily intake of sodium nitrates (V) and (III), respectively), estimated on the basis of a nutritional questionnaire. RESULTS: In both models, acrylamide and nitrates caused a significant decrease in SH group concentrations, but ACR induced stronger changes. The women consumed a greater amount of these nitrogen-containing compounds compared to the men, probably due to their different dietary habits. CONCLUSIONS: The obtained results indicate that these nitrogen-containing xenobiotics are important agents lowering antioxidative plasma potential, hence their intake should be controlled.
WSTĘP: Grupy tiolowe (SH) obecne w osoczu krwi odgrywają ważną rolę w oksydacyjno-antyoksydacyjnej homeostazie organizmu. Są one podatne na niekorzystne działanie różnych czynników egzo- i endogennych. Szczególnie istotnym problemem jest długotrwałe narażenie na różne ksenobiotyki, np. związki zawierające azot, powszechnie występujące w żywności. Celem naszych badań była ocena wpływu akrylamidu (acrylamide – ACR) i azotanu sodu (sodium nitrate – SN) – (V) i (III) – na właściwości przeciwutleniające osocza poprzez pomiar stężenia grup SH. MATERIAŁ I METODY: Stężenie grup SH w osoczu uzyskanym od 62 młodych osób (model in vivo; czas t 0) oraz w próbkach poddanych godzinnej inkubacji z odpowiednim stężeniem ACR i SN (III) (model ex vivo; czas t1) mierzono metodą Ellmana. Stężenia ACR i SN (III) w modelu ex vivo odpowiadały ich dziennemu spożyciu (odpowiednio DIA – daily intake of acrylamide – i DIN – daily intake of sodium nitrates (V) i (III)), oszacowanemu na podstawie kwestionariusza żywieniowego. WYNIKI: W obu modelach akrylamid i azotany spowodowały znaczny spadek stężenia grup SH, ale ACR spowodował silniejsze zmiany. Kobiety spożywały większą ilość związków zawierających azot w porównaniu z mężczyznami, prawdopodobnie z powodu odmiennych nawyków żywieniowych. WNIOSKI: Uzyskane wyniki wskazują, że ksenobiotyki zawierające azot są ważnymi czynnikami obniżającymi potencjał antyoksydacyjny osocza, a ich spożycie powinno być kontrolowane.
Źródło:
Annales Academiae Medicae Silesiensis; 2019, 73; 154-162
1734-025X
Pojawia się w:
Annales Academiae Medicae Silesiensis
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The impact of dietary nitrates and acrylamide intake on systemic redox status in healthy young adults
Autorzy:
Piwowar, Agnieszka
Żurawska-Płaksej, Ewa
Bizoń, Anna
Sawicka, Ewa
Płaczkowska, Sylwia
Prescha, Anna
Powiązania:
https://bibliotekanauki.pl/articles/23370829.pdf
Data publikacji:
2023-12-15
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
acrylamide
nitrates
oxidative stress
intake with food
nutritional survey
oxidative/antioxidative balance
Opis:
Objectives The nitrogen-containing xenobiotics, such as nitrates and acrylamide may potentially influence systemic redox status and contribute to the generation of oxidative stress (OS) in the human body, but there is still a lack of studies that would evaluate the various parameters assessing the oxidative-antioxidant balance. The aim of this study was to evaluate the exposure to nitrates and acrylamide derived from daily diet and to analyze the impact of these nitrate-containing xenobiotics on the parameters of systemic redox status in healthy young adults. Material and Methods To assess nitrate and acrylamide intake in the study population, a semi-quantitative food frequency questionnaire was used. Systemic redox status was evaluated by measurement of a panel of biochemical parameters: enzymatic (glutathione S-transferase, glutathione reductase, glutathione peroxidase [GPx]) and non-enzymatic (uric acid, bilirubin and albumin), thiol/disulphide homeostasis parameters (total thiol, native thiol, and disulfide) and oxidative/ antioxidant balance indicators (total antioxidant status, total oxidant status, OS index). Results The average consumption of nitrates and acrylamide in the study population was 1.24 mg/kg b.w./day and 0.23 μg/kg b.w./day, respectively, which is within the normal value range. Of 12 measured parameters, significant differences were revealed for disulfide and total thiol levels, which were increased in the subgroup with the highest daily intake of nitrates compared to the subgroup with the lowest intake; for GPx, which was highest in the subgroup of the lowest daily intake of acrylamide; and for native thiols in the subgroup with the highest daily intake. Conclusions The intake of nitrogen-containing xenobiotics within the range considered as normal does not markedly influence redox state parameters in healthy young adults. Some significant changes were revealed only for thiol/disulphide homeostasis parameters, which may be the first line of antioxidant defense, as well as for GPx activity. Compensative mechanisms in healthy young people are efficient enough to neutralize OS induced by slightly increased exposure to nitrogen-containing xenobiotics delivered with food.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2023, 36, 6; 773-787
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 20

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