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Wyszukujesz frazę "thermosensitive hydrogels" wg kryterium: Wszystkie pola

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    Wyświetlanie 1-7 z 7
    Tytuł:
    Development of thermosensitive hydrogels of chitosan, sodium and magnesium glycerophosphate for bone regeneration applications
    Autorzy:
    Liškova, J.
    Bačakova, L.
    Skwarczyńska, A.
    Musiał, O.
    Bliznuk, V.
    De Schampelhaere, K.
    Modrzejewska, Z.
    Douglas, T. E. L.
    Powiązania:
    https://bibliotekanauki.pl/articles/284238.pdf
    Data publikacji:
    2017
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    hydrogels
    bone regeneration
    chitosan
    Źródło:
    Engineering of Biomaterials; 2017, 20, no. 143 spec. iss.; 44
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Rheological aspects of the flow of thermosensitive chitosan systems during injection application
    Autorzy:
    Rył, Anna
    Owczarz, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/1034161.pdf
    Data publikacji:
    2020
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    chitosan scaffolds
    injectability
    thermosensitive hydrogels
    Opis:
    The aim of this paper was to conduct preliminary instrumental tests to determine the possibility of injection applications for thermosensitive chitosan systems, including injection needles and application conditions. Among the many biomedical and pharmaceutical applications of chitosan, the minimally invasive thermosensitive scaffolds that form in vivo are an interesting solution. Despite many studies on colloidal chitosan systems undergoing sol-gel phase transition, almost no studies have examined their injectability. It has been stated that the use of acetic acid as a solvent reduces the forces needed for injection. Moreover, the key impact of injection temperature was determined. Storing the medium at room temperature before the injectability test led to a decrease in the value of forces needed for injection. The obtained results are discussed based on the change of the rheological properties of the chitosan hydrogels.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2020, 25; 201-209
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Structural research of thermosensitive chitosan-collagen gels containing alp
    Autorzy:
    Skwarczyńska, Agata
    Biniaś, Dorota
    Modrzejewska, Zofia
    Powiązania:
    https://bibliotekanauki.pl/articles/1034675.pdf
    Data publikacji:
    2016
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    alkaline phosphatase
    chitosan
    collagen
    thermosensitive hydrogels
    Opis:
    Introducing collagen, which is basic ingredient of bone tissue, into the structure of chitosan gels which are formed at the physiological body temperature, is aimed at creating the so-called biomimetic structures, i.e. close in their composition to the natural composition of bone tissue. Within the research the influence of collagen on structural properties of thermosensitive chitosan gels and the influence of ALP on structural properties of chitosan and chitosan-collagen gels was determined.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2016, 21; 176-186
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The influence of the addition of collagen on the rheological properties of chitosan chloride solutions
    Autorzy:
    Owczarz, Piotr
    Rył, Anna
    Modrzejewska, Zofia
    Dziubiński, Marek
    Powiązania:
    https://bibliotekanauki.pl/articles/1034555.pdf
    Data publikacji:
    2017
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    chitosan
    collagen
    rheology
    thermosensitive hydrogels
    viscoelastic behaviour
    Opis:
    Colloidal solutions of chitosan of crab origin with the addition of collagen obtained from cowhide were studied. Were presents the influence of collagen concentration and the method of preparing the sample on the obtained mechanical properties of the solutions and the observed phase transition temperature. Rheological measurements were performed to determine the viscoelastic properties and phase transition temperatures of these solutions. The study was conducted in the temperature range of 5–60°C with the use of classical techniques of rotational rheometry in the cone-plate measurement system. A significant influence of a collagen addition to chitosan chloride solutions on the viscoelastic properties of the systems was observed. The addition of collagen in all the cases increased the sol–gel phase transition temperature in comparison with the chitosan chloride solution containing β-glycerophosphate.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2017, 22; 176-189
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Structural characteristics of thermosensitive chitosan glutaminate hydrogels
    Autorzy:
    Modrzejewska, Zofia
    Nawrotek, Katarzyna
    Zarzycki, R
    Douglas, Timothz
    Powiązania:
    https://bibliotekanauki.pl/articles/1035319.pdf
    Data publikacji:
    2013
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    chitosan
    hydrogel
    natural polymer
    structural properties
    Opis:
    Hydrogels that possess the ability of gelling in response to changes in the local environment, such as pH or temperature, have been examined extensively recently. In this paper the properties of thermosensitive chitosan hydrogels prepared with the use of chitosan glutaminate and -glycerophosphate are presented. The sol/gel transition point was determined based on the rheological properties. The structure of gels was observed under the Scanning Electron Microscopy (SEM) and was investigated by thermogravimetric (TG) and differential themogravimetric (DTG) analy¬sis and infrared (IR) spectroscopy. The crystallinity of gel structure was determined by X-ray Diffraction analysis (XRD).
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2013, 18, 18; 93-105
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Enrichment of thermosensitive chitosan hydrogels with glycerol and alkaline phosphatase for bone tissue engineering applications
    Autorzy:
    Douglas, T. E. L.
    Krok-Borkowicz, M.
    Macuda, A.
    Pietryga, K.
    Pamuła, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/306906.pdf
    Data publikacji:
    2016
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    biomateriały
    kompozyty
    mineralizacja
    hydrożel
    biomaterials
    composites
    mineralization
    hydrogels
    Opis:
    Thermosensitive injectable chitosan hydrogels can be formed by neutralization of acidic chitosan solutions with sodium betaglycerophosphate (Na-β-GP) coupled with increasing temperature to body temperature. Such hydrogels have been considered for applications in bone regeneration. In this study, chitosan hydrogels were enriched with glycerol and the enzyme alkaline phosphatase (ALP) with a view to improving their suitability as materials for bone tissue engineering. Mineral formation was confirmed by infrared spectroscopy (FTIR) and increases in the mass fraction of the hydrogel not consisting of water. Incorporation of ALP in hydrogels followed by incubation in a solution containing calcium ions and glycerophosphate, a substrate for ALP, led to formation of calcium phosphate within the hydrogel. MG-63 osteoblast-like cells were cultivated in eluates from hydrogels containing ALP and without ALP at different dilutions and directly on the hydrogel samples. Hydrogels containing ALP exhibited superior cytocompatibility to ALP-free hydrogels. These results pave the way for the use of glycerol- and ALP-enriched hydrogels in bone regeneration.
    Źródło:
    Acta of Bioengineering and Biomechanics; 2016, 18, 2; 51-57
    1509-409X
    2450-6303
    Pojawia się w:
    Acta of Bioengineering and Biomechanics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Application of texture profile analysis to investigate the mechanical properties of thermosensitive injectable chitosan hydrogels
    Autorzy:
    Owczarz, Piotr
    Rył, Anna
    Wichłacz, Żaneta
    Powiązania:
    https://bibliotekanauki.pl/articles/1034254.pdf
    Data publikacji:
    2019
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    TPA
    chitosan
    hydrogels
    injectable scaffolds
    mechanical properties
    Opis:
    In this paper, the mechanical properties of hybrid chitosan hydrogels were investigated using the texture profile analysis test. Scaffolds obtained from a polysaccharide of various molecular weights were studied, which, with the addition of glycerophosphate salt, formed a three-dimensional structure in vivo. The obtained systems were also enriched with collagen and calcium carbonate to improve the mechanical properties. The determined texture parameter values indicate that the mechanical properties of the hybrid hydrogel depend on the molecular weight of the polymer, the type of solvent and, the pH-neutralizing substance, as well as the type and concentration of the filler. Moreover, in some cases the TPA test was the only way to evaluate the mechanical properties of the obtained hydrogels due to the inability to determine the Young's modulus. Consequently, the texture analysis test is a valuable tool for selecting solutions depending on the intended application of the scaffolds.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2019, 24; 151-163
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-7 z 7

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