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Tytuł:
Acute pulmonary hypertension as a symptom of Bard’s syndrome and pulmonary lymphangitis carcinomatosa – rare manifestation of malignant gastric cancer
Autorzy:
Mazur, Danuta
Romanek, Janusz
Filip, Rafał
Przybylski, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/454787.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
Bard’s syndrome
malignant gastric cancer
pulmonary hypertension
Opis:
Introduction. Acute pulmonary hypertension leading to right ventricular failure and circulatory collapse is usually caused by a pulmonary embolism. However, in extremely rare cases, similar clinical manifestations can be related to another diseases, such as lymphangitis carcinomatosa. Aim. The purpose of this paper is to report on the case of a 29-year-old male patient presented with rapidly progressing dyspnoea. Description of the case. The diagnosis of pulmonary embolism was made on the basis of echocardiographic signs of pulmonary hypertension and right ventricular (RV) dilatation, and the recommended therapy was introduced. On the suspicion of bronchopneumonia, antibiotics and steroids were applied. However, the previously stated diagnosis of pulmonary embolism was not confirmed by the angio-CT scan, which showed small diffusive lung parenchyma intra-biliary nodules (ground glass opacity) with the peripheral appearance of a tree-in-bud sign. Consecutive CT of pelvis and abdomen along with endoscopy revealed a metastatic gastric cancer with the presence of lymphangitis carcinomatosa and miliary dissemination to the lungs. The presence of pulmonary metastases in the course of disseminated gastric cancer is known in literature as Bard’s syndrome. Conclusion. Extrapulmonary malignancies, particularly gastric cancer, should be taken into consideration in differential diagnosis in patients with an acute right ventricular failure and nonspecific lesions in the respiratory system.
Źródło:
European Journal of Clinical and Experimental Medicine; 2019, 2; 179-183
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pulmonary function impairment and airway allergy among workers in traditional bakeries
Autorzy:
Fahim, Ayman E.
El-Prince, Mahmoud
Powiązania:
https://bibliotekanauki.pl/articles/2179769.pdf
Data publikacji:
2013-04-01
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
pulmonary function
allergic sensitization
bakers
Opis:
Objectives: To assess the effect of exposure to flour dust on pulmonary function tests, prevalence of symptoms (respiratory, allergic/irritating) and parameters of allergic sensitization in terms of skin prick test, and bronchial hyper-responsiveness. Material and Methods: 43 bakers (with at least 2 years of occupational exposure) working at different bakeries in Ismailia city, Egypt; and 64 control subjects of comparable socio demographic characteristics were compared. All participants were subjected to an interview questionnaire, clinical chest examination, skin prick test, bronchial hyper-responsiveness test and measurements of pulmonary function parameters. Results: All respiratory and allergic symptoms were more prevalent among bakers compared to the control group, with the highest odds ratio for allergic symptoms (OR = 6.9; p < 0.0001) and dyspnea (OR = 6.3; p = 0.0004). Bakers had a higher percentage of SPT positive results with statistically significant difference between the two groups (p < 0.0001). Bakers had lower observed values compared to the control group with statistically significant difference for FVC, FEV₁/FVC ratio, $ \text{FEF}_\text{75%} $, and $ \text{FEF}_\text{25-75%} $ parameters. Conclusion: The present study suggested that occupational exposure to flour dust may affect respiratory irritation and sensitization, and reduce the pulmonary function tests such as FVC, FEV₁, and FEV₁/FVC ratio and $ \text{FEF}_\text{25-75%} $.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2013, 26, 2; 214-219
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Aqueous leafextracts of Chromolaena odorata and Tridax procumbens attenuated doxorubicin-induced pulmonary toxicity in Wistar rats
Autorzy:
Ikewuchi, C.C.
Ikewuchi, J.C.
Ifeanacho, M.O.
Powiązania:
https://bibliotekanauki.pl/articles/2096805.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Chromolaena odorata
doxorubicin
pulmonary lipids
electrolyte profiles
pulmonary oxidative stress
Tridax procumbens
Opis:
This study investigated the potential protective role of aqueous leafextracts of Chromolaena odorata and Tridax procumbens against pulmonary toxicity induced by doxorubicin. To this end, the effects of these extracts on the profiles of pulmonary biomarkers, lipids and electrolytes were monitored in doxorubicin-treated rats. Doxorubicin was intraperitoneally administered at 15 mg/kg body weight (48 h prior to sacrifice); metformin was orally administered daily at 250 mg/kg body weight (for 14 days); and both extracts were orally administered daily at 50, 75 and 100 mg/kg body weight (for 14 days).The concentrations of pulmonary malondialdehyde, cholesterol, triglyceride, calcium, chloride and sodium of Test control were significantly higher (P < 0.05) than those of the other groups. However, the concentrations of pulmonary ascorbic acid, reduced glutathione, magnesium and potassium as well as pulmonary catalase, glutathione peroxidase and superoxide dismutase activities of Test control were significantly lower (P < 0.05) than those of the other groups.The administration of the extracts prevented doxorubicin-induced adverse alterations in the profiles of pulmonary biomarkers of oxidative stress, cholesterol and electrolytes and maintained them within the normal ranges .Therefore, these herbal preparations from C. odorata and T. procumbens are promising candidates for the prevention/alleviation of doxorubicin-induced pulmonary toxicity.
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2021, 102, 4; 387-398
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A patient with lung cancer and increased right ventricular pressure – should all lung cancer patients be suspected of pulmonary embolism?
Autorzy:
Styczkiewicz, Katarzyna
Mędrek, Sabina
Adamowicz, Adam
Styczkiewicz, Marek
Powiązania:
https://bibliotekanauki.pl/articles/1035688.pdf
Data publikacji:
2019
Wydawca:
Medical Education
Tematy:
lung cancer
pulmonary embolism
pulmonary hypertension
right ventricle pressure
Opis:
Lung cancer is associated with an increased risk of venous thromboembolism, including pulmonary embolism. In some situations, clinical deterioration in patients with lung cancer accompanied by elevated pressure in the right ventricle, usually measured by commonly used echocardiography, may support the diagnosis of pulmonary embolism. However, there are many other causes of increased pressure in the right ventricle in such patients, for example: progression of cancer, pre-existing lung diseases, surgical resection of pulmonary tissue, pnemotoxicity of radiotherapy or concomitant diseases of the left heart. The article presents 2 clinical cases of patients with lung cancer, in which elevated pressure in the right ventricle was resulted from other causes and accompanied the progression of cancer, despite the clinical picture suggesting a pulmonary embolism. Increased pressure in the right ventricle and usually associated pulmonary hypertension, significantly worsen already poor prognosis of patients with lung cancer. The differential diagnosis should, therefore, take into account the whole clinical picture, excluding venous thromboembolism as an important cause of pulmonary hypertension, but also take into account other potential factors to be able to make the right diagnosis and implement optimal treatment as early as possible.
Źródło:
OncoReview; 2019, 9, 2; 45-50
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pulmonary Functions of Welders in Gas Transmission Pipelines in Iran
Autorzy:
Golbabaei, F.
Khadem, M.
Ghahri, A.
Babai, M.
Hosseini, M.
SeyedSomea, M.
Dinari, B.
Powiązania:
https://bibliotekanauki.pl/articles/90327.pdf
Data publikacji:
2013
Wydawca:
Centralny Instytut Ochrony Pracy
Tematy:
fume
pulmonary functions
pulmonary symptoms
welding
spirometric test
funkcje płuc
spawanie
badanie spirometryczne
Opis:
This study evaluated the influence of welding on pulmonary functions in welders. Spirometry tests were performed before and after work shift in 91 welders and 25 clerks (control group). We examined forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), FEV1/FVC ratio and forced expiratory flow 25%–75%(FEF 25–75). Significant differences were found for FVC and FEV1/FVC between welders and the control group in pre- and post-shift measurements (p < .001). In welders, smoking and nonsmoking habit had no significant effects on any pulmonary indices before or after shift. Work experience and fume concentrations also had no significant effects on the majority of spirometric indices (p > .05). Most welders had at least 1 of the respiratory symptoms. Significant differences were found between pre- and post-shift indices (as percentage of predicted values calculated with spirometer) and between the welders engaged in some welding tasks and the control group before work shift. This study documented work-related changes in pulmonary functions in the welders and marked drops in these functions without symptoms in some welders.
Źródło:
International Journal of Occupational Safety and Ergonomics; 2013, 19, 4; 647-655
1080-3548
Pojawia się w:
International Journal of Occupational Safety and Ergonomics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Acute pulmonary embolism as the first manifestation in a COVID-like severe acute respiratory syndrome
Ostra niewydolność oddechowa podobna do COVID jako manifestacja ostrej zatorowości płucnej
Autorzy:
Antonopoulos, Athanassios
Powiązania:
https://bibliotekanauki.pl/articles/1033279.pdf
Data publikacji:
2020
Wydawca:
Towarzystwo Pomocy Doraźnej
Tematy:
CT pulmonary angiography
coronavirus pneumonia
like-COVID-19
pulmonary thromboembolism
Opis:
In the era of new coronavirus infection pulmonary embolism (PE) is a corollary manifestation that may aggravate the patient`s clinical status. In this setting of patients various coagulation abnormalities such as raised D-dimers and prolonged APTT have been reported previously in up to 65% and 45% of adults SARS patients respectively and multiple previously necropsy series of SARS patients showed that vascular thromboses were not uncommonly seen in lung specimens. During this period emergency rooms work is note of worthy in differentiation COVID from non-COVID patients due to separate admission procedure in the hospital. Accordingly, among the non-COVID population there exist a high percentage of patients with a typical radiologic pattern of COVID-19 but without a positive reverse transcription polymerase chain reaction (RT-PCR) resulting in naso-faringeal swamp. The above findings raise the suspicion of an occulted COVID-19 or a like-COVID-19 clinical presentation. In the last istance there is a need to pay more attention just to avoid further contamination. In this report we describe a case with high risk PE, as a first manifestation of a like- COVID-19 pneumonia. In the above case the patient in question, after careful CT angiography evaluation, has a clear COVID-19 pneumonia radiological findings in spite of three RT-PCR swamp negative for true COVID-19.
W erze nowego zakażenia koronawirusem zatorowość płucna (PE) jest następstwem, które może nasilać stan kliniczny pacjenta. W tym przypadku u pacjentów wykazywano różne nieprawidłowości krzepnięcia, takie jak podniesione D-dimery i przedłużone APTT u odpowiednio 65% i 45% dorosłych pacjentów z SARS, zaś w wielu przypadkach sekcja zwłok pacjentów z SARS wykazała, że w płucach nie było rzadkich przypadków zakrzepicy naczyniowej. W tym okresie podczas pracy na ostrym dyżurze wymagane jest odróżnienie pacjentów z COVID i bez COVID, aby przyjąć ich do szpitala. W związku z tym wśród populacji spoza COVID istnieje wysoki odsetek pacjentów z typowym obrazem radiologicznym COVID-19, ale bez dodatniej odwrotnej transkrypcji reakcji łańcuchowej polimerazy (RT-PCR), w wyniku której powstaje zajęcie nosa i gardła. Powyższe ustalenia budzą podejrzenie obrazu klinicznego ukrytego COVID-19 lub podobnego do COVID-19. W ostatnim przypadku należy zwrócić większą uwagę tylko w celu uniknięcia dalszego zainfekowania. W tym raporcie opisane został przypadek PE o wysokim ryzyku, jako pierwszy przejaw podobnego zapalenia płuc COVID-19. W powyższym przypadku badany pacjent, po dokładnej ocenie angiografii CT, ma jasne wyniki radiologiczne zapalenia płuc COVID-19 pomimo trzech negatywnych wyników RT-PCR dla prawdziwego COVID-19.
Źródło:
Critical Care Innovations; 2020, 3, 2; 51-57
2545-2533
Pojawia się w:
Critical Care Innovations
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pulmonary tuberculosis in childhood: clinical features, treatment side effects and factors associated with radiologic improvement
Autorzy:
Batmaz, S.B.
Powiązania:
https://bibliotekanauki.pl/articles/2088011.pdf
Data publikacji:
2020
Wydawca:
Uniwersytet Opolski. Instytut Nauk o Zdrowiu
Tematy:
child
prognosis
pulmonary
radiological
tuberculosis
Opis:
Background: Tuberculosis (TB) is a common public health problem and early diagnosis and treatment is important. Aim of the study: The aim was to evaluate complaints and radiological features, drug side effects, changes in radiological findings after treatment, and to evaluate the factors affecting this change in patients with pulmonary TB. Material and methods: One hundred patients with pulmonary TB were evaluated, and the following data recorded: age, gender, contact with TB patient, complaints, physical examination, tuberculin skin test, acid resistant bacillus, polymerase chain reaction and culture results, posteroanterior/lateral chest radiographs and thorax computed tomography findings at presentation and after treatment, treatment duration, and side effects. Treatment adherence and follow-up data were evaluated, and radiological findings before and after treatment were compared. In predicting radiological improvement, the effects of age, sex, duration of complaints, living in in rural/urban areas, treatment duration, treatment adherence, follow-up, and presence of cavitation were examined. Results: Mean age was 6.0 ± 4.2 years. 66 of the patients had contact history with TB patients. The most common complaint was cough, whilst infiltration and/or mediastinal lymphadenopathy were the most common findings in radiological examination at presentation. 84 patients were scheduled a treatment program for 6 months. Improvement in radiological findings were significantly better in patients who adhered to medication and follow-up protocols. Age, sex, complaint duration, living in rural/urban areas, treatment duration and presence of cavitation were not significantly associated with radiological improvement. Conclusions: Pulmonary TB should be considered in patients presenting with cough, even if their physical examination and chest radiographs are normal. Adherence to anti-tuberculosis treatment and follow-up were the most important factors in radiological improvement.
Źródło:
Medical Science Pulse; 2020, 14, 1; 4-9
2544-1558
2544-1620
Pojawia się w:
Medical Science Pulse
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Impairment of pulmonary function and changes in the right cardiac structure of pneumoconiotic coal workers in China
Autorzy:
Bian, Lu-Qin
Zhang, Yue
Jiang, Rong
Mao, Ling
Powiązania:
https://bibliotekanauki.pl/articles/2177031.pdf
Data publikacji:
2015-02-24
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
coal worker’s pneumoconiosis
pulmonary artery systolic pressure
pulmonary function
right cardiac structure
Opis:
Introduction: Information on the changes of pulmonary function and the right cardiac structure in patients with coal worker’s pneumoconiosis in China is very scarce. This study was performed to clarify the changes of pulmonary function and right cardiac structure in patients with coal worker’s pneumoconiosis in China. Material and methods: Pulmonary function, pulmonary artery systolic pressure, and the right cardiac structure were evaluated by spirometry and color Doppler echocardiography. Results: The pulmonary artery systolic pressure of patients with coal worker’s pneumoconiosis was increased with disease severity. Patients with coal worker’s pneumoconiosis also exhibited an impaired pulmonary function and altered right cardiac structure compared with control subjects. A significant linear correlation of the variables of pulmonary ventilation and diffusion function with the indicators of the right cardiac structure was found in patients with coal worker’s pneumoconiosis in China. Conclusions: This study elucidated a deterioration of pulmonary function and right cardiac structure in patients with coal worker’s pneumoconiosis in China.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2015, 28, 1; 62-70
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Neurogenic pulmonary edema induced by subarachnoid hemorrhage; case report on diagnostic and therapeutic implications
Autorzy:
Weiss, Guenter
Meyer, Frank
Powiązania:
https://bibliotekanauki.pl/articles/1395592.pdf
Data publikacji:
2015-04-01
Wydawca:
Index Copernicus International
Tematy:
neurogenic pulmonary edema
subarachnoidal hemorrhage
catecholamine
Opis:
An exemplary rare case of neurogenic pulmonary edema induced by intracranial hemorrhage was reported including diagnostic and therapeutic implications as well as management recommendations. A 35-year old man who was treated first by a neurosurgical approach because of a subarachnoid hemorrhage (bore hole trepanation) and subsequently on a surgical intensive care unit because of severe postoperative hemodynamic, cardiocirculatory, and pulmonary disruptions. To monitor cardiopulmonary condition and treatment effects, a Swan-Ganz catheter was placed in the pulmonary artery, since after trepanation, a critical cardiopulmonary status developed during postoperative mechanical ventilation and catecholamine administration. This condition was indicated by neurogenic pulmonary edema detected by control chest X-ray film and high oxygen load in the inspiratory air required for sufficient arterial oxygenation. After use of high positive end-exspiratory pressure (PEEP) (initially directed against neurogenic lesion), adaptation of initial dobutamine doses, initiation of norepinephrine administration, and substitution of fluids, the patient's blood pressure finally rose sufficiently to sustain regular cerebral blood perfusion and achieve better arterial oxygenation. Thus, the patient‘s cardiopulmonary condition stabilized and temporary cardiac insufficiency could be overcome. Subsequently, it became possible to decrease PEEP according to requirements to prevent or limit cerebral edema and to diminish catecholamine doses.
Źródło:
Polish Journal of Surgery; 2015, 87, 4; 189-193
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pulmonary function of jute mill workers from West Bengal, India
Autorzy:
Mandal(Majee), A.
Majumder, R.
Powiązania:
https://bibliotekanauki.pl/articles/1914021.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
pulmonary function
jute workers restrictive/obstructive respiratory symptoms
odds ratio
Opis:
Background: Jute industry workers constantly exposed themselves to jute dust and are at risk of impairment of lung function. Investigation on various studies revealed the effects of exposure to jute dust but limited studies so far undertaken regarding its bearing on pulmonary function of jute workers of West Bengal,India. Purpose: To evaluate the respiratory status of jute mill workers of West Bengal exposed to occupational hazards. Materials and Methods: This cross sectional study was conducted on 203 male jute mill workers of age range 18 – 60 yrs. from West Bengal and a control group of 141 men of similar age .Dynamic pulmonary function parameters were carried out including physical parameters, respiratory abnormalities, year of exposure and smoking history. Results: FVC, FEV1, FEF 200-1200 and PEFR values of higher age group non smoker of low dust zone were significantly higher in comparison to the non smoker of high dust zone. The prevalence of chest tightness was 33.49% and liver dysfunction was 41.9% in dusty zone workers of jute mill in comparison to less dusty zone. Again, incidence of chest tightness and cough was highest (35.44%) in higher age group workers and prevalence of byssinosis like symptoms and chronic bronchitis was 30- 37% after 10 – 30years of exposure. But occurrence of bronchial asthma was 11.9% in workers of greater than 20 years of exposure. Prevalence of all the above respiratory abnormalities was higher among smokers than non-smokers. Conclusions: Concentration of jute dust exposure had been associated with decrease in FVC, FEV1, and PEFR with a higher risk of developing chronic bronchitis, bronchial asthma, byssinosis and other respiratory symptoms. This indicated high occupational health hazards which would create an alarming situation, if remained unchecked.
Źródło:
Progress in Health Sciences; 2014, 4, 1; 7-17
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Organic dust induced pulmonary disease - the role of mould derived beta-glucan
Autorzy:
Rylander, R
Powiązania:
https://bibliotekanauki.pl/articles/51765.pdf
Data publikacji:
2010
Wydawca:
Instytut Medycyny Wsi
Tematy:
organic dust
pulmonary disease
disease risk
beta-glucan
endotoxin
mould
inhalation
inflammation
Źródło:
Annals of Agricultural and Environmental Medicine; 2010, 17, 1; 9-13
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Recurrent pulmonary embolism in a patient with renal tumor
Autorzy:
Kępski, Jarosław
Kurzyna, Marcin
Szmit, Sebastian
Powiązania:
https://bibliotekanauki.pl/articles/1062547.pdf
Data publikacji:
2017
Wydawca:
Medical Education
Tematy:
clear cell carcinoma
heparin
pulmonary embolism
renal tumor
thrombosis
vena cava filter
Opis:
Venous thromboembolism is one of the main causes of sudden death in hospitalized patients. Among the classical risk factors involved, cancer occupies a special place. Up to 20% of oncological patients will develop a VTE episode, and in 10% of them, it will be a direct cause of death. In the case presented below, incidental pulmonary embolism and renal tumor were diagnosed at the same time, and there was an event of embolism despite optimal antithrombotic treatment. Such a scenario of complications may correlate with a clinically advanced stage of cancer, and may be associated with a poorer prognosis, requiring an individualized therapeutic management.
Źródło:
OncoReview; 2017, 7, 4; 171-175
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Exhaled nitric oxide in smokers and former smokers with chronic obstructive pulmonary disease
Autorzy:
Galiniak, S.
Aebisher, D.
Rachel, M.
Powiązania:
https://bibliotekanauki.pl/articles/2087917.pdf
Data publikacji:
2020
Wydawca:
Uniwersytet Opolski. Instytut Nauk o Zdrowiu
Tematy:
nitric oxide
smoking
respiratory diseases
chronic obstructive pulmonary disease
Opis:
Background: Measurement of fractional exhaled nitric oxide (FeNO) is a useful technique for detection of eosinophilic airway inflammation and assessment of efficiency of corticosteroid treatment in patents with respiratory disease. Generally studies agree that measurement of FeNO is a useful non-invasive biomarker in patients with chronic obstructive pulmonary disease (COPD), however, there are reports that do not confirm such a relationship between FeNO and COPD. Aim of the study: The main objective of this study was to investigate FeNO levels in Polish patients with COPD compared to healthy controls. As a secondary objective, we assessed the influence of smoking on FeNO levels in healthy patients, and patients with COPD. Material and methods: FeNO concentration was measured using an electrochemical analyzer in healthy nonsmokers (n=21), healthy smokers (n=25), and former smokers with COPD (n=30) and smokers with COPD (n=38). General characteristics, hematological variables and serum biochemical parameters were also obtained and analyzed using the Kruskal-Wallis test. Results: FeNO measurement revealed significantly reduced NO levels in healthy smokers compared to healthy non-smokers, former smokers with COPD and smokers with COPD (median [range]: 14 [6–17] vs. 21 [15–29], 25 [15–53], and 19 [11–32] ppb, respectively, p<0.001). Moreover, we found increased FeNO levels in ex-smokers with COPD compared with smokers with COPD (p<0.05). No associations between FeNO and other analyzed parameters were found. Conclusions: Levels of FeNO, measured by with an electrochemical analyzer, were elevated among patients with COPD compared to healthy non-smoking controls. Moreover, our study confirms that smoking results in a reduction in FeNO concentration in both healthy patients and patients with COPD.
Źródło:
Medical Science Pulse; 2020, 14, 2; 36-43
2544-1558
2544-1620
Pojawia się w:
Medical Science Pulse
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of platelet indexes as potential biomarkers of suspected pulmonary embolism
Autorzy:
Wójcik, Mariusz
Daszyk-Wójcik, Joanna
Skoczyński, Kamil
Powiązania:
https://bibliotekanauki.pl/articles/454999.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
mean platelet volume
platelet count
platelet distribution width
pulmonary embolism
Opis:
Introduction. Pulmonary embolism is one of the most frequent cardiovascular diseases, potentially leading to death. There is no validated biomarker with both high specificity and sensitivity. Aim. The aim of the study was to define the diagnostic importance of platelet count (PLT), mean platelet volume (MPV) and platelet distribution width (PDW) on acute pulmonary embolism. Material and methods. We retrospectively reviewed the medical records of 145 patients with clinically suspected acute pulmonary embolism admitted to the Emergency Department. Demographic data and laboratory tests were collected on admission. All patients underwent computed tomography (CT) angiography. Results. The total data of 145 patients were analyzed, including 65 patients (67±17 years; 30 men/35 women) with acute pulmonary embolism confirmed with CT and 80 patients (67±19 years; 26 men/54 women) with negative CT. The MPV did not differ between the patients with acute PE and the control group (8.0 fL [IQR: 7.6-8.4] vs. 7.9 fL [IQR: 7.4-8.7], p=0.45). There were no significant differences in PLT (220x10³/mm³ [IQR: 172-274] vs. 243x10³/mm³ [IQR: 186-286], p=0.12) and PDW (59.0 ± 6.9% vs. 57.2 ± 7.3%, p=0.12). Conclusions. Our results suggest that platelet indexes (at a single time point) are not a reliable diagnostic biomarkers of acute pulmonary embolism.
Źródło:
European Journal of Clinical and Experimental Medicine; 2019, 2; 113-117
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Echokardiograficzne rozpoznanie slingu płucnego ze zwężeniem początkowego odcinka lewej gałęzi tętnicy płucnej i drożnym przewodem tętniczym
Ultrasound diagnosis of pulmonary sling with proximal stenosis of left pulmonary artery and patent arterial duct
Autorzy:
Mądry, Wojciech
Karolczak, Maciej A.
Powiązania:
https://bibliotekanauki.pl/articles/1059305.pdf
Data publikacji:
2013
Wydawca:
Medical Communications
Tematy:
echocardiography
high parasternal echocardiographic views
left pulmonary artery stenosis
persistent ductus arteriosus
pulmonary sling
echokardiografia
przetrwały przewód tętniczy
sling płucny
wysokie projekcje przymostkowe
zwężenie lewej tętnicy płucnej
Opis:
Authors discuss methods of echocardiographic diagnosis of the pulmonary sling with stenosis and hypoplasia of the left pulmonary artery and patent arterial duct with massive left‑to‑right shunt, based on a case of the newborn with resistant to treatment heart failure, with initial diagnosis of patent ductus arteriosus, referred to surgical treatment. The optimal echocardiographic views permitting establish diagnosis of the pulmonary sling were suggested. The special attention was paid to high parasternal and suprasternal views visualizing vessels of the upper mediastinum as well as characteristic differences between the normal and pathologic picture. The typical features of the echocardiogram suggesting pulmonary sling, like the lack of the left pulmonary artery in its expected position, and the abnormal branching pattern of the right pulmonary artery were indicated. The greatest diagnostic difficulties in visualization of the abnormal route of the left pulmonary artery were related to the presence of air‑containing tissues, like lungs and central airways between the ultrasound probe and area of interest. The other was the masking influence of the large patent arterial duct, that may mimic the left pulmonary artery arising from the pulmonary trunk. The other entities requiring differentiation with sling, like aplasia of the left lung, the direct or indirect aortic origin of the left pulmonary artery, were discussed. The role of other visualization technics, like computed 3D tomography, and magnetic nuclear resonance, as well as direct visualization of central airways with bronchoscopy in establishing precise diagnosis were stressed.
Autorzy przedstawiają metodykę badania echokardiograficznego slingu płucnego z towarzyszącym zwężeniem i hipoplazją lewej gałęzi tętnicy płucnej, z drożnym przewodem tętniczym oraz masywnym przeciekiem aortalno‑płucnym na przykładzie noworodka z oporną na leczenie zachowawcze niewydolnością krążeniowo‑oddechową. Pacjenta skierowano do Kliniki Kardiochirurgii celem leczenia operacyjnego, ze wstępnym rozpoznaniem drożnego przewodu tętniczego. W prezentowanej pracy przedstawiono optymalne projekcje echokardiograficzne ułatwiające ustalenie rozpoznania. Zwrócono szczególną uwagę na przydatność wysokich projekcji przymostkowych i projekcji nadmostkowych obrazujących naczynia górnego śródpiersia. Wymieniono elementy obrazu echokardiograficznego, które powinny nasuwać podejrzenie slingu, a także sposoby ich uwidocznienia. Należą do nich brak lewej gałęzi tętnicy płucnej w typowej lokalizacji – w przedłużeniu pnia płucnego oraz obecność dodatkowej gałęzi odchodzącej od prawej tętnicy płucnej w połowie jej długości. Wskazano na możliwe trudności diagnostyczne wynikające z obecności powietrznej tkanki płucnej oraz centralnych dróg oddechowych przesłaniających struktury naczyniowe, a także na problem maskującego wpływu przewodu tętniczego, który może imitować prawidłowy przebieg lewej gałęzi tętnicy płucnej. Przedstawiono jednostki chorobowe wymagające różnicowania ze slingiem, takie jak agenezja lewego płuca i różne postaci odaortalnego ukrwienia lewego płuca, oraz główne cechy umożliwiające ich wykluczenie. Podkreślono znaczenie innych metod diagnostyki obrazowej, takich jak tomografia komputerowa i rezonans magnetyczny, a także metody bezpośredniego obrazowania centralnych dróg oddechowych przy użyciu bronchoskopii.
Źródło:
Journal of Ultrasonography; 2013, 13, 52; 104-110
2451-070X
Pojawia się w:
Journal of Ultrasonography
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 220

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