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Tytuł:
Induced isozyme polymorphism in spring barley mutants
Autorzy:
Kucharska, M
Maluszynski, M
Powiązania:
https://bibliotekanauki.pl/articles/2047711.pdf
Data publikacji:
1996
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
polymorphism
isoenzyme
barley
induced mutant
mutant
Opis:
The usefulness of mutagenic treatment to enlarge isozymic variability of barley and the use of induced mutants for genetic analysis were evaluated. N-methyl-N-nitroso urea, sodium azide and gamma rays were employed as mutagenic agents. Electrophoretic assays of 3848 M₂ seedlings obtained by chemical mutagenic treatment of the spring barley cultivars Dema, Aramir, Bielik and 3100 M₂ seedlings obtained by physical mutagenic treatment of the cv. Dema revealed 70 isozymic mutants, which represent 30 separate mutants in 25 M₁ plants. Most of mutations (27) were induced by chemical mutagen at polymorphic esterase loci. The occurrence of induced mutants at monomorphic loci, Got2 and Lap2, made it possible to perform genetic analysis of those loci in barley including mapping respective genes within chromosomes.
Źródło:
Journal of Applied Genetics; 1996, 37, 1; 1-9
1234-1983
Pojawia się w:
Journal of Applied Genetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Polymorphism - prose of Java programmers
Autorzy:
Spławski, Zdzisław
Powiązania:
https://bibliotekanauki.pl/articles/764549.pdf
Data publikacji:
2006
Wydawca:
Uniwersytet Marii Curie-Skłodowskiej. Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej
Źródło:
Annales Universitatis Mariae Curie-Skłodowska. Sectio AI, Informatica; 2006, 4, 1
1732-1360
2083-3628
Pojawia się w:
Annales Universitatis Mariae Curie-Skłodowska. Sectio AI, Informatica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Polymorphism of Cepaea nemoralis (L., 1758) in Warsaw
Autorzy:
Pomagalski, R.
Powiązania:
https://bibliotekanauki.pl/articles/83277.pdf
Data publikacji:
2016
Wydawca:
Uniwersytet Mikołaja Kopernika. Wydział Biologii i Ochrony Środowiska. Stowarzyszenie Malakologów Polskich
Tematy:
land snail
snail
polymorphism
grove snail
brown-lipped snail zob.grove snail
Cepaea nemoralis
Warsaw city
Źródło:
Folia Malacologica; 2016, 24, 1
1506-7629
Pojawia się w:
Folia Malacologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Morphological diversity and dna polymorphism of common oat (Avena sativa L.) landraces cultivated in Poland.
Autorzy:
Nowosielska, Dorota
Nowosielski, Jarosław
Powiązania:
https://bibliotekanauki.pl/articles/2199164.pdf
Data publikacji:
2008-12-21
Wydawca:
Instytut Hodowli i Aklimatyzacji Roślin
Tematy:
common oat
DNA polymorphism
landraces
morphological traits
Opis:
The aim of the work was characterization of morphological diversity and DNA polymorphism of common oat landraces. 25 Morphological traits and DNA polymorphism have been examined using AFLP methods. It has been found, that identification of oat landraces is possible based on the examined morphological traits. The examined accessions were differentiated by traits important for intraspecific taxonomy of oat: type of panicle, presence of awns, colour of grain, as well as other morphological traits, such as shape of panicle, rigidity of stem leaves, and type of awns. Relationships of morphological traits of leaves, grains, and stem with some DNA fragments suggesting presence of molecular markers of these morphological traits have been found. Morphological similarity of landraces doesn’t correspond to affinity complied with DNA similarity of these objects...
Źródło:
Plant Breeding and Seed Science; 2008, 58; 11-22
1429-3862
2083-599X
Pojawia się w:
Plant Breeding and Seed Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Monadic Printing Revisited
Autorzy:
Grzanek, K.
Powiązania:
https://bibliotekanauki.pl/articles/108664.pdf
Data publikacji:
2016
Wydawca:
Społeczna Akademia Nauk w Łodzi
Tematy:
functional programming
monads
Haskell
polymorphism
Opis:
Expressive and clear implementation of monadic printing requires an amount of work to define and design proper abstractions to rely upon when performing the actual programming works. Our previous realization of tree printing library left us with a sense of lack with respect to these considerations. This is why we decided to re-design and re-implement the library with core algorithms based upon new, effective and expressive text printing and concatenation routines. This paper presents the results of our work.
Źródło:
Journal of Applied Computer Science Methods; 2016, 8 No. 1; 66-79
1689-9636
Pojawia się w:
Journal of Applied Computer Science Methods
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Current problems in the research of Cepaea polymorphism
Autorzy:
Ozgo, M.
Powiązania:
https://bibliotekanauki.pl/articles/84741.pdf
Data publikacji:
2008
Wydawca:
Uniwersytet Mikołaja Kopernika. Wydział Biologii i Ochrony Środowiska. Stowarzyszenie Malakologów Polskich
Opis:
Shell polymorphism in the land snails of the genus Cepaea has been studied for more than a century. Although these studies have taught us much about the ways in which evolutionary forces work at the population level, many problems are still unresolved. Studies of shell polymorphism, especially in populations living at the edges of the species’ geographical distribution, long-term surveys of morph frequencies in selected populations, studies of the dispersal abilities of Cepaea snails and of differences in physiology and behaviour among morphs will help to answer outstanding questions, which have direct relevance to our understanding of microevolutionary processes generally.
Źródło:
Folia Malacologica; 2008, 16, 2
1506-7629
Pojawia się w:
Folia Malacologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Expression and polymorphism of defensins in farm animals
Autorzy:
Bagnicka, Emilia
Strzałkowska, Nina
Jóźwik, Artur
Krzyżewski, Józef
Horbańczuk, Jarosław
Zwierzchowski, Lech
Powiązania:
https://bibliotekanauki.pl/articles/1040309.pdf
Data publikacji:
2010
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
farm animals
expression
defensins
polymorphism
Opis:
Due to their activity against bacteria, viruses, and fungi, antimicrobial peptides are important factors in the innate resistance system of humans and animals. They are called "new generation antibiotics" for their potential use in preventive and therapeutic medicine. The most numerous group of antimicrobial peptides is a family of cationic peptides which include defensins and cathelicidins. Among them the most common are peptides with a beta-sheet structure containing three intra-molecular disulphide bonds, called defensins, comprising three classes: alpha, beta, and theta. The class of beta-defensins is the largest one. Their transcripts have been found in many tissues of humans and animals. The aim of this paper is to present the current knowledge about antimicrobial peptides from the defensin family in farm animals, their expression, polymorphism, as well as the potential of their use as genetic markers of health and production traits.
Źródło:
Acta Biochimica Polonica; 2010, 57, 4; 487-497
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Polymorphism in Syringa rDNA regions assessed by PCR technique
Autorzy:
Smolik, M.
Andrys, D.
Franas, A.
Krupa-Malkiewicz, M.
Malinowska, K.
Powiązania:
https://bibliotekanauki.pl/articles/41641.pdf
Data publikacji:
2010
Wydawca:
Polska Akademia Nauk. Instytut Dendrologii PAN
Tematy:
polymorphism
lilac
Syringa
rDNA region
polymerase chain reaction
Opis:
The Syringa genus is characterizedby a multiplicity of forms. Its chief asset is the ornamental value of thousands of accessions, species or hybrids. From a phylogenetic point of view the genus is difficult in an explicit classification due to its frequently complex genome. The aim of this study was to determine the possibility for the identification of genotypic diversity and genetic relationships in the nrDNA sequence of some selected Syringa accessions – part of a collection of the Dendrological Garden in Przelewice (Poland). For this purpose, the PCR technique together with a combination of various ‘universal’ primers designed for the nrDNA sequence analysis were employed. Fourteen Syringa accessions: Syringa × chinensis Willd., S. × prestoniae Mc Kelv., S. × prestoniae ‘Telimena’, S. × prestoniae ‘Jaga’, S. × prestoniae ‘Basia’, S. meyeri ‘Palibin’, S. vulgaris ‘Miss Ellen Willmott’, S. vulgaris, S. vulgaris ‘Jules Simon’, S. vulgaris ‘Katherine Havemeyer’, S. vulgaris ‘Krasawica Moskvy’, S. vulgaris ‘Mirabeau’, S. vulgaris ‘Madame Lemoine’ and S. vulgaris ‘Niebo Moskvy’ made up the research material. In the conducted amplifications, genetic profiles were obtained for 14 combinations among the 25 combinations of different pairs of primers used. The nrDNA templates coding the small subunit (SSU), 5.8S subunit andITS1, ITS2 andIGS sequences were amplified. In PCR reactions a total of 33 PCR products were generated, of which 21 (64%) products were polymorphic, 6 (18%) monomorphic and6 (18%) were genotype-specific. For the lilac accessions examined246 amplicons were generated from ~230 to ~1100 bp in length. The analysis of both the dendrogram and the genetic similarity matrix revealedlow diversity between the examinedaccessions. For most they rangedfrom 70 to 80%, andthe greatest diversity (87%) was foundbetween the S. × prestoniae: ‘Basia’ and‘Telimena’ accessions, while the lowest (57%) was observed between S. vulgaris ‘Katherine Havermeyer’ and S. × chinensis.
Źródło:
Dendrobiology; 2010, 64
1641-1307
Pojawia się w:
Dendrobiology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
CTRC gene polymorphism may increase pancreatic cancer risk – preliminary study
Autorzy:
Głuszek, Stanisław
Kowalik, Artur
Kozieł, Dorota
Wawrzycka, Iwona
Głuszek-Osuch, Martyna
Matykiewicz, Jarosław
Powiązania:
https://bibliotekanauki.pl/articles/1393315.pdf
Data publikacji:
2017
Wydawca:
Index Copernicus International
Tematy:
pancreatic cancer
CTRC polymorphism
etiology
Opis:
Pancreatic cancer is often fatal due to delayed diagnosis and treatment difficulties. Objective: To analyze selected SPINK1, CTRC, CFTR, and PRSS1 gene mutations in cancer tissue and blood samples of patients with pancreatic tumors. Materials and method: We enrolled 16 consecutive patients diagnosed with pancreatic tumors. We collected cancer tissue, normal pancreatic tissue, and blood samples for genetic tests. The control group consisted of 419 healthy individuals. Peripheral blood samples were collected from all study participants in EDTA-coated tubes. Results: Out of 16 patients with pancreatic tumors, 12 had pancreatic cancer on microscopic examination (mean age, 60.2 years). The CTRC polymorphism Hetero p.G60=(c.180C>T) was found in 5 patients with pancreatic cancer (41.7% vs. 18.6% in the control group). One patient with pancreatic cancer and a positive family history had the SPINK1 (p.N34S) mutation [8.3% vs. 2.9% (12/419) in the control group]. One patient with pancreatic cancer had the CTRC (p.R254W) mutation [8.3% vs. 1% (4/419) in the control group]. Conclusions: Our preliminary results show that the CTRC polymorphism p.G60= (c.180C>T) is frequent in patients with pancreatic cancer. However, further research is needed to verify our findings.
Źródło:
Polish Journal of Surgery; 2017, 89, 5; 48-53
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Morphological Diversity and Dna Polymorphism of Common Oat (Avena Sativa L.) Breeding Varieties Cultivated in Poland
Autorzy:
Nowosielska, Dorota
Nowosielski, Jarosław
Powiązania:
https://bibliotekanauki.pl/articles/2199038.pdf
Data publikacji:
2009-12-20
Wydawca:
Instytut Hodowli i Aklimatyzacji Roślin
Tematy:
breeding varieties
common oat
DNA polymorphism
morphological traits
Opis:
The aim of the work was characterization of morphological diversity and DNA polymorphism of common oat breeding varieties. 25 morphological traits and DNA polymorphism have been examined using AFLP and RAPD methods. It has been found, that identification of oat breeding varieties is possible based on the examined morphological traits...
Źródło:
Plant Breeding and Seed Science; 2009, 60; 31-44
1429-3862
2083-599X
Pojawia się w:
Plant Breeding and Seed Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The PPARA gene polymorphism in team sports athletes
Autorzy:
Ahmetov, Ildus I.
Egorova, Emiliya S.
Mustafina, Leysan J.
Powiązania:
https://bibliotekanauki.pl/articles/1054633.pdf
Data publikacji:
2013
Wydawca:
Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
Tematy:
PARA
game performance
gene polymorphism
sport selection
team sports
Opis:
Peroxisome proliferator-activated receptor α (PPARα) is a transcription factor that regulates lipid and glucose metabolism. Accumulating evidence suggests that the intron 7 C allele of the PPARA gene rs4253778 G/C polymorphism has an advantage for power-oriented athletes, presumably due to the hypertrophic effects on skeletal muscle and increase in glucose utilization in response to anaerobic exercise. The G allele, however, is said to be favorable for the endurance-oriented athletes. The metabolic demands of team sports involve aerobic and anaerobic energy pathways, as a result of the intermittent physical activity. The aim of the present study was to investigate the association between the PPARA gene polymorphism and team-sport athletic status. A total of 665 Russian athletes from 14 team sports and 1,706 controls were involved in the case-control study. We found that the frequency of the PPARA C allele was significantly higher in athletes compared to controls (20.5 vs. 16.4%, P = 0.0009), suggesting that anaerobic rather than aerobic metabolism may be crucial to the game performance in team sports. This means that our study indicates the association between the PPARA gene G/C polymorphism and team-sport athletic status. Although more replication studies are needed, the preliminary data suggest an opportunity to use the analysis of PPARA polymorphism, along with other gene variations and standard phenotypic assessment in team sports selection.
Źródło:
Central European Journal of Sport Sciences and Medicine; 2013, 1, 1; 19-24
2300-9705
2353-2807
Pojawia się w:
Central European Journal of Sport Sciences and Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The angiotensin converting enzyme gene i/d polymorphism in Polish rowers
Autorzy:
Jastrzębski, Zbigniew
Leońska-Duniec, Agata
Kolbowicz, Marek
Tomiak, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1055139.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
Tematy:
ACE I/D polymorphism
athlete status
rowers
sport genetics
Opis:
Angiotensin converting enzyme gene (ACE) is the most frequently investigated genetic marker in the context of genetic conditioning of athletic predispositions. The product of the gene is a key component of the renin-angiotensin system (RAS) and the kallikrein-kinin system (KKS), mainly responsible for the regulation of blood pressure. The main aim of the study was to determine the possible interaction between the ACE I/D polymorphism and endurance athlete status in a group of Polish rowers in comparison with sedentary individuals. 121 male Polish rowers, members of academic sports clubs, and 115 unrelated volunteers, were recruited for the study. The PCR amplification of the insertion (I) or deletion (D) fragment of the ACE gene was performed. Compared with control group, the frequency of the I allele differ significantly from that found in rowers (57.4% vs. 44.3%; P=0.013) and the ACE genotype frequency amongst the whole cohort of rowers (30.6% II, 53.7% ID, 15.7% DD) was also different from expected values (control group 19.1% II, 50.4% ID, 30.4% DD; P=0.017). Our investigation confirms a positive association of the I allele of the ACE gene with endurance athlete status in a group of Polish rowers.
Źródło:
Central European Journal of Sport Sciences and Medicine; 2014, 5, 1; 77-82
2300-9705
2353-2807
Pojawia się w:
Central European Journal of Sport Sciences and Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
SSCP polymorphism within 5 region of bovine lactoglobulin [LGB] gene
Autorzy:
Kaminski, S
Zabolewicz, T.
Powiązania:
https://bibliotekanauki.pl/articles/2044462.pdf
Data publikacji:
1998
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
lactoglobulin gene
polymorphism
SSCP method
cattle
gene transcription
electrophoresis
hormonal receptor
mutation
beta-lactoglobulin
milk
Opis:
In the paper the detection of the SSCP polymorphism within the 5’ fragment of bovine beta-lactoglobulin (LGB) gene is described. The 5’ fragment of LGB gene (209 bp) was PCR-amplified and then subjected to electrophoresis allowing the detection of SSCP polymorphism. Among 124 animals (50 cows and 74 bulls) six SSCP patterns were identified and named Rl, R2, R3, R4, R5 and R6, which occured with the frequency of 0.32, 0.51, 0.09, 0.06, 0.01 and 0.01, respectively. The PCR-SSCP method is simple, fast, and relatively inexpensive. The SSCP polymorphism reported in the paper may be useful in looking for the associations between different SSCP patterns and LGB gene expression and milk properties.
Źródło:
Journal of Applied Genetics; 1998, 39, 1; 97-102
1234-1983
Pojawia się w:
Journal of Applied Genetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Lack of correlation between X region spa polymorphism and virulence of methicillin resistant and methicillin sensitive Staphylococcus aureus strains
Autorzy:
Kurlenda, Julianna
Grinholc, Mariusz
Szweda, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/1040442.pdf
Data publikacji:
2010
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
polymorphism
protein A
spa
virulence
Opis:
Staphylococcus aureus is an etiological factor of severe infections in both hospital and ambulatory environments. As methicillin resistant Staphylococcus aureus strains spread quickly across healthcare centers resulting in life-threatening infections with increased mortality, they are considered more virulent than MSSA strains. Protein A, encoded by the spa gene, is one of the virulence factors involved in the staphylococcal pathogenesis. It has been suggested that the number of 24-bp tandem repeat units along the X region of the spa gene correlates with the virulence level of the strains. The current work analyzed the relationships between the virulence of MRSA and MSSA strains with region X polymorphism. No obvious correlation was observed.
Źródło:
Acta Biochimica Polonica; 2010, 57, 1; 135-138
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Source and significance of genetic polymorphism of selected parasitic Protozoa
Autorzy:
Majewska, A.C.
Sulima, P.
Powiązania:
https://bibliotekanauki.pl/articles/838111.pdf
Data publikacji:
1998
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
parasite
polymorphism
control
Giardia
Trypanosoma
epidemiology
evolution
parasite population
Cryptosporidium
Protozoa
Toxoplasma
taxonomy
Źródło:
Annals of Parasitology; 1998, 44, 3
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Association and polymorphism study of seven candidate genes with reproductive traits in three pig breeds in Hungary
Autorzy:
Hunyadi-Bagi, Ágnes
Balogh, Péter
Nagy, Krisztina
Kusza, Szilvia
Powiązania:
https://bibliotekanauki.pl/articles/1038827.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
reproduction traits
pig
polymorphism
genes
Hungary
Opis:
Seven genes (BF, EGF, ESR, FSHB, H2AFZ, LEP and PRLP) were studied as candidate gene influencing eleven reproduction traits (interval between litters (IBL), percent of litter (PL), number of litters (NL), number of piglets born dead (NBD), number of piglet born alive (NBA), total number born (TNB), mean of born alive (MBA), mean of born dead (MBD), mean of born total (MBT), mean of piglets at 21 days of age (M21D) and growth rate (GR) in three pig breeds (Hungarian Large White (HLW), Duroc and Pietrain) by PCR-RFLP. Based on the observed vs. expected genotypes frequencies populations across loci were in Hardy-Weinberg equilibrium (P>0.05). In case HLW breed ESR and FSHβ genes were in disequilibrium. Association study suggested that only EGF gene showed significant influence on the trait NBA and TNB. The AA genotype are preferable for sows, associated with higher NBA and TNB. The longest IBL, and the highest NL is associated with AB and AA genotype of EGF gene. IBL is significantly shorter in case of pigs with AB and AA alleles than BB alleles of PRLP genes. Selection for these SNPs could improve the reproductivity in the studied breeds.
Źródło:
Acta Biochimica Polonica; 2016, 63, 2; 359-364
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Association between a nucleotide polymorphism in the calpain 10 gene and carbohydrate metabolism disturbances in patients with polycystic ovary syndrome
Autorzy:
Szydlarska, Dorota
Machaj, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/552368.pdf
Data publikacji:
2016
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
diabetes
hyperandrogenism
single nucleotide polymorphism.
Źródło:
Family Medicine & Primary Care Review; 2016, 4; 497-500
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
An analysis of PPARGC1A gene polymorphism in relation to carcass quality in PIC hybrid fatteners
Analiza polimorfizmu genu PPARGC1A w odniesieniu do cech tuszy tuczników hybrydowych PIC
Autorzy:
Polasik, D.
Glodek, A.
Rybarczyk, A.
Powiązania:
https://bibliotekanauki.pl/articles/45231.pdf
Data publikacji:
2013
Wydawca:
Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
Tematy:
PPARGC1A gene
gene polymorphism
polymorphism
carcass quality
hybrid
fattener
Opis:
The aim of this study was to determine the association between polymorphism located in exon 8 of PPARGC1A gene (Cys430Ser) and carcass quality in pigs. Experiment was carried out on 350 PIC hybrid fatteners. Polymorphism was analyzed using PCR-RFLP method. The frequency of genotypes was as follows: AA – 0.33, AT – 0.57, TT – 0.1, however alleles: A – 0.62, T – 0.38. In the analyzed population loss of Hardy-Weinberg equilibrium was observed (P ≤ 0.01). Statistical analysis showed that only one of the evaluated traits was associated with individual PPARGC1A genotypes. Cooling loss value for pig carcasses with TT genotype was statistically significant (P ≤ 0.05) higher than observed in those with AA and AT genotypes.
Celem niniejszych badań było wykazanie zależności pomiędzy polimorfizmem zlokalizowanym w 8 eksonie genu PPARGC1A (Cys430Ser) a cechami tuszy świń. Eksperyment został przeprowadzony na 350 tucznikach hybrydowych PIC. Polimorfizm analizowano z użyciem metody PCR-RFLP. Frekwencja genotypów była następująca: AA - 0.33, AT - 0.57, TT - 0.1, natomiast alleli: A - 0.62, T - 0.38. W analizowanej populacji zaobserwowano zachwianie równowagi genetycznej Hardy’ego-Weinberga (P ≤ 0,01). Analiza statystyczna wykazała, że tylko jedna z ocenianych cech była powiązana z poszczególnymi genotypami PPARGC1A. Wartość strat chłodzenia (%) dla świń z genotypem TT była statystycznie istotnie (P ≤ 0,05) wyższa niż obserwowana u osobników z genotypami AA i AT.
Źródło:
Acta Scientiarum Polonorum. Zootechnica; 2013, 12, 4
1644-0714
Pojawia się w:
Acta Scientiarum Polonorum. Zootechnica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Polimorfizm języka naturalnego a twierdzenia Kurta Gödla
Autorzy:
Gomułka, Łukasz
Powiązania:
https://bibliotekanauki.pl/articles/2158817.pdf
Data publikacji:
2015
Wydawca:
Instytut Studiów Międzynarodowych i Edukacji Humanum
Tematy:
language
polymorphism
Opis:
The aim of this paper is to outline Stanisław Lem’s (1921-2006) original views on Kurt Gödl’s theorems. The project consists of five concise paragraphs in which such issues are discussed: the introduction with an explanation of selected terms: a natural language, polymorphism. The author of the article presents a short outline of certain mathematical problems, that is the problems of arithmetics and the history of trying to prove its absolute non-contradiction. The author also includes Gödl’s theorems into the greatest achievements of the scientific thought of 20th century (limitation theorems). After that, epistemological questions of Kurt Gödl’s theorems are introduced together with their original interpretation according to Stanisław Lem. The author of the paper emphasizes that this prominent philosopher and writer introduces cultural-linguistic interpretation of Gödl’s discoveries, thus suggesting that a natural language overcomes ‘Gödl-made abyss’ thanks to its characteristic polymorphism.
Źródło:
Prosopon. Europejskie Studia Społeczno-Humanistyczne; 2015, 3(12); 25-33
1730-0266
Pojawia się w:
Prosopon. Europejskie Studia Społeczno-Humanistyczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
p53 codon 72 polymorphism in cervical cancer patients and healthy women from Poland.
Autorzy:
Dybikowska, Aleksandra
Dettlaff, Agnieszka
Konopa, Krzysztof
Podhajska, Anna
Powiązania:
https://bibliotekanauki.pl/articles/1044272.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
p53 gene
codon 72 polymorphism
cervical carcinoma
Opis:
A polymorphism at codon 72 of gene p53 results in the presence of either arginine or proline at this position. We investigated the distribution of p53 codon 72 polymorphism in cervical cancer patients and a control group of healthy women from Poland. Our results do not confirm the hypothesis that the p53 codon polymorphism could play a role as a factor for squamous carcinoma of the cervix.
Źródło:
Acta Biochimica Polonica; 2000, 47, 4; 1179-1182
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The genetic polymorphism in the STK11 does not affect gestational diabetes
Autorzy:
Alharbi, Khalid
Khan, Imran
Eldesouky, Malek
Al-Hakeem, Malak
Abotalib, Zeinab
Powiązania:
https://bibliotekanauki.pl/articles/1039007.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
gestational diabetes
STK11
rs8111699 polymorphism
Saudi women
Opis:
Gestational diabetes mellitus (GDM) is defined as carbohydrate intolerance of variable severity that develops during pregnancy. Recent studies indicate that GDM onset is rapid, and that women with GDM will develop other metabolic disorders such as obesity, type 2 diabetes, and cardiovascular disease in their future. Serine/threonine kinase 11 (STK11) is engaged in the insulin signaling pathway and encoded protein is an important activator of adenosine monophosphate activated protein kinase. Based on the previously reported association between the STK11 gene and diabetes, we aimed to investigate whether the rs8111699 polymorphism in STK11 has any role in gestation diabetes in Saudi women. In this case-control study, we recruited pregnant Saudi women based on biochemical analysis of their blood samples. Genomic DNA was obtained from confirmed subjects (200 GDM cases and 300 non-GDM). PCR-RFLP analysis was performed to detect the C528G polymorphism in the STK11 gene. The anthropometric and clinical data were similar between the GDM and non-GDM subjects (p > 0.05), whereas the biochemical analysis was significantly different between the cases and controls (p < 0.05). The genotype and allele frequencies between of the STK11 gene were not statistically significant difference between the GDM and non-GDM groups (OR=0.82; 95% CI:=0.6-1.0; p=0.12). Our study suggests that the rs8111699 polymorphism has no role in the development of GDM in pregnant Saudi women.
Źródło:
Acta Biochimica Polonica; 2015, 62, 3; 569-572
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The use amelogenin gene polymorphism in PCR embryo sexing in bovine IVF embryos
Autorzy:
Lechniak, D
Cumming, J R
Powiązania:
https://bibliotekanauki.pl/articles/2046605.pdf
Data publikacji:
1997
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
polymorphism
sex chromosome
Y chromosome
bovine embryo
sex
amelogenin gene
polymerase chain reaction
embryo
Opis:
The present study describes a rapid, simple method of bovine IVF embryo sexing by use of PCR technique. A pair of primers corresponding to the bovine amelogenin sequence has been used. The Rapid Cycler (Idaho Technology, USA) used in the current experiment enabled the PCR programme consisting of 55 cycles to be completed in less than 40 minutes. Therefore the total sexing procedure could be performed in less than 90 minutes. The described method succeded in case of 85% analysed embryos.
Źródło:
Journal of Applied Genetics; 1997, 38, 1; 45-49
1234-1983
Pojawia się w:
Journal of Applied Genetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
DNA polymorphism in locus D1S80 in Poland. DNA profiling and detection of new alleles by heteroduplex formation between alleles of the same size
Autorzy:
Kwiatkowska, J
Dziechciowska, K
Lisiecka, D
Slomski, R
Powiązania:
https://bibliotekanauki.pl/articles/2046677.pdf
Data publikacji:
1997
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
DNA sequence
polymorphism
Polska
hybridization
Polish population
heteroduplex formation
DNA polymorphism
same size
polymerase chain reaction
allele
distribution
Opis:
We have analysed allele distribution at the highly polymorphic variable number of tandem repeats (VNTR) locus D1S80 (pMCT118) in the Polish population using the, polymerase chain reaction (PCR) technique. Characteristics of the D1S80 locus makes it a very useful marker for population genetic research, genetic linkage studies and forensic identification of individuals. During our routine application of the D1S80 marker to paternity testing in several cases of homozygosity detected by polyacrylamide gel electrophoresis, heteroduplex formation for alleles 18 and 24 was also observed. Direct sequencing of PCR products revealed that alleles 18 and 24 of locus D1S80 actually represent a mixture composed of different sequences. Our observations indicate that identification of some 18 and 24 VNTR alleles based only on size estimated in electrophoretic analyses could lead to errors in paternity testing and DNA profiling.
Źródło:
Journal of Applied Genetics; 1997, 38, 3; 335-341
1234-1983
Pojawia się w:
Journal of Applied Genetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Preliminary report on β-casein gene Met183QVal183 polymorphism in Romanian indigenous Zackel sheep breeds
Autorzy:
Kusza, Szilvia
Ilie, Daniela
Sauer, Maria
Sauer, Ioan-Walter
Gavojdian, Dinu
Powiązania:
https://bibliotekanauki.pl/articles/1038660.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
β-casein
gene polymorphism
ovine milk
Racka
Turcana
Opis:
Genetic polymorphisms of the milk protein genes are important because of their effects on quantitative traits and technological properties of milk manufacturing. In the present study we identified the polymorphism of the beta-casein gene in two local sheep breeds (Racka n=98 and Turcana n=111) in Romania. The most studied variants at the ovine beta-casein (CSN2) locus are: A and G variants. Genomic DNA was extracted from hair follicles and beta-casein genotypes were determined by the rapid TaqMan (Applied Biosystems, USA) genotyping assay. Homozygote genotypes GG were not detected in any of the studied breeds. In both, the Racka and Turcana breeds, the A variant had a much higher frequency, 0.98% and 0.97%, respectively. In the current study, the fast DNA tests for genotyping ovine CSN2 were successfully optimized, however, further samples and correlations of genomic results with milk characteristics and production data are needed for the development of future selection schemes of the Romanian indigenous sheep breeds, with the ultimate purpose to produce low allergen level sheep milk and derived dairy products.
Źródło:
Acta Biochimica Polonica; 2017, 64, 2; 339-341
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Associations between bovine beta-lactoglobulin polymorphism within coding and regulatory sequences and milk performance traits
Autorzy:
Kaminski, S
Zabolewicz, T.
Powiązania:
https://bibliotekanauki.pl/articles/2043147.pdf
Data publikacji:
2000
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
chromosome
polymorphism
promoter
haplotype
beta-lactoglobulin gene
mutation
cattle breeding
amino acid
milk
dairy cattle
protein content
Źródło:
Journal of Applied Genetics; 2000, 41, 2; 91-99
1234-1983
Pojawia się w:
Journal of Applied Genetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of the effect of centromeric heterochromatin polymorphism on pig fertility
Autorzy:
Kozubska-Sobocinska, A
Danielak-Czech, B
Slota, E
Rejduch, B
Powiązania:
https://bibliotekanauki.pl/articles/2047265.pdf
Data publikacji:
1996
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
pig
polymorphism
constitutive heterochromatin
fertility
C-banding
centromeric heterochromatin
litter size
karyotype
Opis:
C-banding identified centromeric heterochromatin polymorphism, most often located in pair no. 16, was a basis for selecting animals for the experiment. The aim of the experiment was to assess the impact of centromeric heterochromatin polymorphism on pig fertility, expressed by litter size. The research included the first two litters obtained from 30 pairs of parents with different genotypes as regards the parameter under study. A statistical analysis of the number of offspring from different mating types showed no significant differences between the experimental groups of animals. The results obtained did not confirm suggested correlation between polymorphism of the centromeric heterochromatin regions and pig fertility, estimated by mean litter size. Thus the polymorphism cannot be regarded as a selection criterion.
Źródło:
Journal of Applied Genetics; 1996, 37, 3; 293-298
1234-1983
Pojawia się w:
Journal of Applied Genetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Relationship between transferrin and globulin antigen polymorphism and sheep resistance to mastitis
Autorzy:
Charon, K M
Lipecka, C
Siudek, T
Swiderek, W P
Skiba, E
Powiązania:
https://bibliotekanauki.pl/articles/2047286.pdf
Data publikacji:
1996
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
transferrin genotype
polymorphism
sheep
milk infection
health condition
mammary gland
mastitis
globulin antigen
Opis:
The effect of transferrin genotypes and genes and globulin antigens on sheep resistance/susceptibility to mastitis was analysed. The udder health condition was diagnosed on the basis of the somatic cell count in 1 ml of milk and results of bacteriological tests. It was found that sheep with the transferrin genotype AC, AD and CC were characterised by a better health of the mammary gland than the remaining ewes. Among 9 transferrin alleles observed in the examined sheep, only the presence of transferrin I allele in the ewes genotype was connected with the somatic cell count below the mean value of this trait. The presence of transferrin A allele in the sheep's genotype was connected with a small infection of milk with mastitis pathogens. The serum globulin antigens analysed did not significantly affect the somatic cell count in the milk of the examined ewes. However, the antigens A2, NS1 (antigens of ß-globulin) and GB2 (antigen of class IgG immunoglobulins) as well as the globulin antigen A6 and GA1 antigen of class IgG immunoglobulins showed to have a significant effect on the level of sheep milk infection.
Źródło:
Journal of Applied Genetics; 1996, 37, 2; 161-172
1234-1983
Pojawia się w:
Journal of Applied Genetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Determination of polymorphism of IS-1311 sequence in Mycobacterium avium subspecies paratuberculosis strains isolated from milk samples
Autorzy:
Szteyn, J.
Bednarko-Młynarczyk, E.
K. Liedke
Wiszniewska-Łaszczych, A.
Wojtacka, J.
Powiązania:
https://bibliotekanauki.pl/articles/2087864.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Mycobacterium avium subsp. paratuberculosis
milk
IS-1311 polymorphism
Źródło:
Polish Journal of Veterinary Sciences; 2017, 4; 827-829
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Genetic polymorphism of CSN2 gene in Banat White and Carpatina goats
Autorzy:
Kusza, Szilvia
Ilie, Daniela
Sauer, Maria
Nagy, Krisztina
Patras, Irina
Gavojdian, Dinu
Powiązania:
https://bibliotekanauki.pl/articles/1038785.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
beta-casein gene
goats
polymorphism
Banat White
Carpatina
hypoallergenic milk
Opis:
The main objective of the current study was to obtain preliminary results on genetic polymorhism of A and C variants at the CSN2 locus in indigenous Romanian goat (Banat White, Carpatina) breeds using a rapid and efficient genotyping method, TaqMan assay (Applied Biosystems, USA). Hair follicle samples were taken from 73 Banat White and 82 Carpatina purebred goats from Arad, Caras-Severin and Timis counties. After the optimization of the genotyping assay it was found that the most frequent allele at the CSN2 locus was C in Banat White breed, while CSN2*A and CSN2*C showed similar frequencies in Carpatina breed (0.51 and 0.49, respectively). All three genotypes were detected in the two studied breeds, however, AA was the least frequent, especially in Banat White. The studied polymorphisms are potential markers for milk production in the studied breeds and the results will be useful in future works aimed at identifying possible associations with milk production traits, in order to test the feasibility of producing hypoallergenic organic goat milk.
Źródło:
Acta Biochimica Polonica; 2016, 63, 3; 577-580
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Microsatellite DNA polymorphism in sturgeon species and their hybrids reared in Polish aquaculture farms
Autorzy:
Fopp-Bayat, D.
Luczynski, M.
Powiązania:
https://bibliotekanauki.pl/articles/363194.pdf
Data publikacji:
2006
Wydawca:
Uniwersytet Warmińsko-Mazurski w Olsztynie
Tematy:
jesiotr
identyfikacja gatunkowa
DNA mikrosatelitarne
hybrydy
polimorfizm
hybrids
microsatellite DNA
polymorphism
PCR
species identification
sturgeons
Opis:
Highly variable microsatellite DNA loci show high levels of variation per locus and provide molecular markers for species and for populations of small effective size. In this study we applied microsatellite markers to identify specimens belonging to several sturgeon species and their interspecific hybrids. Nine microsatellite loci (Afu-19, Afu-22, Afu-34, Afu-39, Afu-54, Afu-57, Afu-58, Afu-68, Afu-69) were analysed for five species (beluga, Siberian sturgeon, Russian sturgeon, sterlet and paddlefish) and for their three interspecific hybrids: Siberian sturgeon x Russian sturgeon, beluga x sterlet (called bester) and for beluga x bester. Certain alleles at five loci: Afu-22, Afu-39, Afu-54, Afu-57 and Afu-68 were diagnostic for the examined sturgeon species and their interspecific hybrids.
Źródło:
Environmental Biotechnology; 2006, 2, 1; 11-19
1734-4964
Pojawia się w:
Environmental Biotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Genetic research in modern sport
Autorzy:
Leońska-Duniec, Agata
Powiązania:
https://bibliotekanauki.pl/articles/1054958.pdf
Data publikacji:
2013
Wydawca:
Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
Tematy:
athlete status
physical activity
polymorphism
sport genetics
Opis:
Sport genomics is a comparatively new scientific discipline concentrating on the organization and functioning of the genome of elite athletes. It seems to be the most promising tool for sport selection, individualization of the training process, sport traumatology, and also in illegal ‘gene doping’. With genotyping more available, research of gene variants’ influence on several phenotype traits related to physical performance have been widely carried out worldwide. This review not only summarizes the current findings of sport genomics study of molecular markers, their association with athlete status and training responses, but it also explores future trends and possibilities. The importance of genetics in modern sport increases every year. However, the recent studies still represent only the first steps towards a better understanding of the genetic factors that influence human physical abilities, and therefore continuing studies are necessary.
Źródło:
Central European Journal of Sport Sciences and Medicine; 2013, 3, 3; 19-26
2300-9705
2353-2807
Pojawia się w:
Central European Journal of Sport Sciences and Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Utilization of specific primers in legume allergens based polymorphism screening
Autorzy:
Klongová, Lucia
Kováčik, Adam
Urbanová, Lucia
Kyseľ, Matúš
Ivanišová, Eva
Žiarovská, Jana
Powiązania:
https://bibliotekanauki.pl/articles/2086185.pdf
Data publikacji:
2021
Wydawca:
Państwowa Wyższa Szkoła Zawodowa w Tarnowie
Tematy:
legume
profilins
vicilin
specific primer
polymorphism
roślina strączkowa
profiliny
wicylina
starter specyficzny
polimorfizm
Opis:
Different types of allergies became a part of life of many people around the world. The research activities connecting to allergens are actually not oriented only for protein and immunological interactions, but to the genomic and transcriptomic background of them, too. Analysis and description of genomic variability of allergens in plant food resources will help to manage the allergen based strategies in the future. Here, the bioinformatic approach was used to develop and validate the specific primers for genomic screening of polymorphism of profilins (Profilin Based Amplicon Polymorphism; PBAP) and vicilins (Vicilin Based Amplicon Polymorphism; VBAP) among the legumes. The alignment of existing public databases data for these allergens in the group of legumes was performed. Subsequently, specific primers were designed and their ability to generate polymorphic amplicons were tested for three legumes – bean, lentil and chickpeas. In all cases, amplicons were generated and polymorphism was detected in all three species for profilin as well as for vicilin.
Źródło:
Science, Technology and Innovation; 2021, 13, 2; 12--21
2544-9125
Pojawia się w:
Science, Technology and Innovation
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The relation of PON1-L55M gene polymorphism and clinical manifestation of Behcets disease
Autorzy:
Dursun, Ahmet
Cicek, Salih
Keni, Fatih
Karakas-Celik, Sevim
Sezer, Tuna
Altinyazar, Cevdet
Powiązania:
https://bibliotekanauki.pl/articles/1039286.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
PON1 gene
Polymorphism
Behçet's disease
Opis:
Purpose: Behçet's disease is a multisystem disease characterized by recurrent oral and genital ulcers, relapsing uveitis, mucocutaneous, articular, gastrointestinal, neurologic, and vascular manifestations. Paraoxonase is believed to play an important role in protection of LDL and HDL particles from oxidation, in antioxidant effect against lipid peroxidation on cellular membranes, and in anti-inflammatory process. Lipid peroxidation and free oxygen radicals have been thought to play a role in pathogenesis of BD. The association of paraoxonase gene polymorphisms with Behçet's Disease in a group of Turkish patients with clinical manifestations and healthy controls has been investigated. Patients and Methods: Paraoxonase (PON-1-L55M) gene polymorphism was investigated in 50 Behcet patients and 50 healthy individuals with a PCR/RFLP method. Results: There were significant differences between patients and the control group in allele frequencies of the PON1 L55M polymorphism (p=0.04). Also, when patients were compared with the control group according to clinical manifestations, this statistical significance was getting sharper. Compared with the PON55 L allele, the M allele was associated with greater than 3.5 fold (OR 3.5, 95% CI 1.3-8.9) increased risk of ocular (OR 2.4, 95% CI 1.1-5.3), 2.4 fold joint and 3.1 fold (OR 3.1, 95% CI 1.1-8.4) central nervous system manifestations of BD. Conclusion The PON L55M gene polymorphism seemed to play a role in the pathogenesis of BD.
Źródło:
Acta Biochimica Polonica; 2014, 61, 2; 271-274
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Allelic polymorphism of endothelial NO-synthase gene and its functional manifestations
Autorzy:
Dosenko, Victor
Zagoriy, Vyacheslav
Haytovich, Nikolay
Gordok, Olga
Moibenko, Alexey
Powiązania:
https://bibliotekanauki.pl/articles/1041240.pdf
Data publikacji:
2006
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
activity of nitric oxide synthase
endothelial nitric oxide synthase
RNA expression
platelets
allelic polymorphism
Opis:
Investigation of the mechanisms of phenotypic realization of allelic polymorphism of the eNOS gene has shown that the level of eNOS mRNA and activity of this enzyme in platelets depends from genotype. We identified a T-786→C polymorphism in the promoter region, a variable number of tandem repeats (4a/4b) in intron 4 and the G894→T polymorphism in exon 7 of the eNOS gene in isolated human platelets. We measured eNOS mRNA in isolated platelets by reverse transcription-PCR and eNOS enzyme activity by fluorimetric detection system FCANOS-1 using diaminofluorescein diacetate (DAF-2A). It was shown that the level of eNOS mRNA is the lowest for the -786C/C promoter genotype. In exon 7 homozygotes (894T/T) the level of RNA is lower than in normal homozygotes (894G/G), but higher than in heterozygotes (894G/T). The eNOS activity in platelets is lower in carriers of the 786C/C promoter genotype than in normal homozygotes (2.1 × P=0.03), and lower comparing to heterozygotes (2.9 × P>0.05). The eNOS activity accompanying the 894T/T variant of exon 7 is also lower than in normal homozygotes (P>0.05). Regarding the polymorphism in intron 4 - the enzyme's activity is lower in carriers of the 4a/4a genotype comparing to normal homozygotes (1.7 × P>0.05) and lower than in heterozygotes (1.9 × P>0.05). These results allow one to conclude that the T-786→C polymorphism of the eNOS gene promoter most significantly affects the gene expression and eNOS activity.
Źródło:
Acta Biochimica Polonica; 2006, 53, 2; 299-302
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Polymorphism of nine canine-derived microsatellites in farm silver foxes [Vulpes fulvus]
Autorzy:
Zajac, M
Klukowska, J.
Slomski, R.
Switonski, M.
Powiązania:
https://bibliotekanauki.pl/articles/2043146.pdf
Data publikacji:
2000
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
polymorphism
Vulpes fulvus
Canidae
microsatellite
silver fox
dog
farm
genome
genetic marker
fox
blue fox
Źródło:
Journal of Applied Genetics; 2000, 41, 1; 43-50
1234-1983
Pojawia się w:
Journal of Applied Genetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Polymorphism of DNA in nematodes of genus Trichinella Railliet, 1895 according to the data of polymerase chain reaction
Autorzy:
Shendrick, A.
Benedictov, I.
Bessonov, A.
Powiązania:
https://bibliotekanauki.pl/articles/838885.pdf
Data publikacji:
1998
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
polymorphism
Trichinella pseudospiralis
Trichinella
nematode
polymerase chain reaction
DNA
Trichinella spiralis
Źródło:
Annals of Parasitology; 1998, 44, 3
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Matrix metalloproteinase-2 C-1306T promoter polymorphism and breast cancer risk in the Saudi population
Autorzy:
Saeed, Hesham
Alanazi, Mohammad
Alshahrani, Omair
Parine, Narasimha
Alabdulkarim, Huda
Shalaby, Manal
Powiązania:
https://bibliotekanauki.pl/articles/1039541.pdf
Data publikacji:
2013
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
breast cancer
matrix metalloproteinases
single nucleotide polymorphism
TaqMan Allele Discrimination assay
Opis:
Matrix metalloproteinase-2 (MMP-2) is an enzyme with proteolytic activity against matrix proteins, particularly basement membrane constituents. A single nucleotide polymorphism (SNP) at -1306, which disrupts a Sp1-type promoter site (CCACC box), displayed a strikingly lower promoter activity with the T allele. In the present study, we investigate whether this MMP-2 SNP is associated with susceptibility to breast cancer in the Saudi population. Ninety breast cancer patients and 92 age matched controls were included in this study. TaqMan Allele Discrimination assay and DNA sequencing techniques were used for genotyping. The results showed that, the frequency of MMP-2 CC wild genotype was lower in breast cancer patients when compared with healthy controls (0.65 versus 0.79). The homozygous CC (OR=2, χ2=5.36, p=0.02) and heterozygous CT (OR=1.98, χ2=4.1, p=0.04) showing significantly high risk of breast cancer in the investigated group. In conclusion our data suggest that the MMP-2 C-1306T polymorphism may be associated with increased breast cancer risk in the Saudi population.
Źródło:
Acta Biochimica Polonica; 2013, 60, 3; 405-409
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Genetic diversity in Vernonia amygdalina Delile accessions revealed by random amplified polymorphic DNAs (RAPDs)
Autorzy:
Aikpokpodion, P.
Abebe, J.
Igwe, D.
Powiązania:
https://bibliotekanauki.pl/articles/79809.pdf
Data publikacji:
2018
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
genetic diversity
Vernonia amygdalina
random amplified polymorphic DNA
polymorphism
molecular characteristics
single-nucleotide polymorphism
geographic differentiation
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2018, 99, 2
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Plasminogen activator inhibitor 1 (PAI-1) 1334G/A genetic polymorphism in colorectal cancer.
Autorzy:
Smolarz, Beata
Romanowicz-Makowska, Hanna
Kulig, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1043627.pdf
Data publikacji:
2003
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
PCR
1334G/A polymorphism
prognostic marker
colorectal cancer
plasminogen activator inhibitor 1 (PAI-1)
Opis:
Plasminogen activator inhibitor 1 (PAI-1) content in colorectal cancer tissue extracts may be of strong prognostic value: high levels of PAI-1 in tumours predict poor prognosis. The gene encoding PAI-1 is highly polymorphic and PAI-1 gene variability could contribute to the level of PAI-1 biosynthesis. In the present work the distribution of genotypes and frequency of alleles of the 1334G/A polymorphism in 92 subjects with colorectal cancer in samples of cancer tissue and distant mucosa samples as well as in blood were investigated. Blood samples age matched healthy individuals (n = 110) served as control. The 1334G/A polymorphism was determined by PCR amplification using allele specific primers. No differences in the genotype distributions and allele frequencies between blood, distant mucosa samples and cancer tissue were detected. However, the distribution of the genotypes of the 1334G/A polymorphism in patients differed significantly (P <0.05) from those predicted by the Hardy-Weinberg equilibrium. There were significant differences in the frequencies of alleles between the colorectal cancer subjects and controls (P <0.05). The results support the hypothesis that the 1334G/A polymorphism may be associated with the incidence of colorectal cancer.
Źródło:
Acta Biochimica Polonica; 2003, 50, 2; 489-495
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Polymorphism in intron 23 of the endothelial nitric oxide synthase gene (NOS3) is not associated with hypertension.
Autorzy:
Derebecka, Natalia
Hołysz, Marcin
Dankowski, Rafał
Wierzchowski, Michał
Trzeciak, Wiesław
Powiązania:
https://bibliotekanauki.pl/articles/1043838.pdf
Data publikacji:
2002
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
nitric oxide synthase
gene polymorphism
hypertension
intron 23
Opis:
Nitric oxide (NO) is synthesised in the vascular endothelium by nitric oxide synthase (NOS3) and is an important factor in the regulation of blood pressure. Impaired synthesis of NO due to mutations in the NOS3 gene is associated with hypertension. To date several allelic variants of the NOS3 gene have been identified and their possible linkage with hypertension investigated. We studied the distribution of genotypes and frequency of alleles of the G11T polymorphism in intron 23 of the NOS3 gene in patients with hypertension and in a control group of healthy individuals. The polymorphism was determined by PCR-RFLP analysis. The distribution of genotypes in the patients with hypertension and in the healthy individuals did not differ significantly from the values predicted from Hardy-Weinberg equilibrium for the general population. No major differences in the distribution of the G11T polymorphism in the patients and healthy individuals were found (P > 0.05).
Źródło:
Acta Biochimica Polonica; 2002, 49, 1; 263-268
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Genetic polymorphism and quantitative variation of alpha-amylases from rye endosperm
Autorzy:
Masojc, P
Lapinski, M.
Larsson-Raznikiewicz, M.
Powiązania:
https://bibliotekanauki.pl/articles/2048192.pdf
Data publikacji:
1995
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
chromosome
rye
Secale cereale
colorimetric assay
isoenzyme
alpha-amylase
electrophoresis
endosperm
isoelectric focusing
immunoelectrophoresis
cereal cultivar
genetic polymorphism
Opis:
α-Amylase isozymes from rye endosperm were analysed by means of isoelectric focusing, polyacrylamide gel electrophoresis, immunoelectrophoresis and colorimetric assay. Α-AMY 1 (high pI) group was separated into 13 IEF bands, whereas in group α-AMY2 (low pI) 2 intensive and 6-8 faint bands were found. Two linked (2±1 cM) polymorphic loci and a single locus with two alleles encoding for α-AMY 1 and α-AMY 2 groups, respectively, were identified after genetic analysis of the IEF patterns. All α-amylase isozymes developed on PAGE, were shown to belong to α-AMY 1 group. It was demonstrated that a single PAGE isozyme corresponds to 2-4 separate IEF bands and that most of the IEF bands can be attributed to more than one PAGE isozyme. The activity of α-amylases from PAGE zone I was 2.3 times higher than the activity of zone II isozymes. A strong correlation between the activity and protein amount of particular α-AMY 1 isozymes (r=0.94) was found.
Źródło:
Journal of Applied Genetics; 1995, 36, 3; 197-204
1234-1983
Pojawia się w:
Journal of Applied Genetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Development of microsatellite markers for horse-chestnut (Aesculus hippocastanum), their polymorphism in natural Greek populations, and cross-amplification in related species
Autorzy:
Walas, L.
Iszkulo, G.
Barina, Z.
Dering, M.
Powiązania:
https://bibliotekanauki.pl/articles/2078223.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Instytut Dendrologii PAN
Tematy:
Tertiary relict
endemic species
cross-amplification
polymorphism
Opis:
New nuclear microsatellite markers (SSRs) were developed for Aesculus hippocastanum, a relict tree species from the Balkan Peninsula. The development of microsatellites was done using the Illumina MiSeq PE300 platform. Out of a set of 500 SSRs designed, a subset of 13 loci was tested using 290 individuals from seven natural populations. Twelve species-specific loci were polymorphic. The number of alleles per locus ranged from 2 to 17 and expected heterozygosity from 0.089 to 0.800 with a mean value of 0.484. The population of Kalampaka had the lowest value of allelic richness (2.63) and gene diversity in comparison to the remaining populations. STRUCTURE analysis confirmed isolation of population Mariolata from the southern edge of the species range and genetic similarity among populations from the Pindos Mts. Additionally, the utility of new SSRs in 29 individuals from nine other Aesculus taxa was tested. Eleven markers gave polymorphic products for all tested species. For 24 individuals, a high-quality product was obtained for each marker. Results confirmed the utility of specific markers for future population genetics studies.
Źródło:
Dendrobiology; 2021, 85; 105-116
1641-1307
Pojawia się w:
Dendrobiology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Polimorficzność motywacji osób twórczych. Implikacje pedagogiczne
Autorzy:
Aneta, Bartnicka-Michalska,
Powiązania:
https://bibliotekanauki.pl/articles/892405.pdf
Data publikacji:
2015
Wydawca:
Uniwersytet Warszawski. Wydawnictwa Uniwersytetu Warszawskiego
Tematy:
interpreting artist
efficient personality
polymorphism of motivation
Opis:
In the article the hypothesis of motivational polymorphism in creativity is formulated and confirmed. The hypothesis assumes that activation of creative behaviour needs many different types of motivation, which are variations of one main motivation. The theoretical basis of this article rests on Józef Kozielecki’s concept of psychotransgressionism, which assumes that creative behaviour can be activated by three motivations: self-esteem motivation (hubristic), motivation of the meaning of life and motivation of self-efficiency. In this study on a sample of interpreting artists (N = 133), creative behaviour was measured using the STZ questionnaire (Strzałecki 2003). The motivational orientations were measured using the Polish adaptation of Power Motivation Scale (PMS) by Tokarz and Trzebińska (2011), the Polish adaptation of Life Attitude Profile questionnaire (LAP-R) by Klamut (2010) and the Polish adaptation of General Self- Efficacy Scale questionnaire (GSES) by Juczyński (2001). The results confirmed the hypothesis of a polymorphic nature of motivation in creative people. Educational implications of results are discussed.
Źródło:
Kwartalnik Pedagogiczny; 2015, 60(3 (237)); 34-52
0023-5938
Pojawia się w:
Kwartalnik Pedagogiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Genetic polymorphism of Klotho gene and bladder cancer risk
Polimorfizm genu Klotho a ryzyko raka pęcherza moczowego
Autorzy:
Szymczak, Agnieszka
Forma, Ewa
Krześlak, Anna
Jóźwiak, Paweł
Bryś, Magdalena
Madej, Adam
Różański, Waldemar
Powiązania:
https://bibliotekanauki.pl/articles/1032775.pdf
Data publikacji:
2012
Wydawca:
Łódzkie Towarzystwo Naukowe
Tematy:
genetic polymorphism
klotho
bladder cancer
snp
polimorfizm genów
rak pęcherza
Opis:
Introduction: Bladder cancer is the most frequent tumor of the urinary tract in Poland. Klotho gene can act as an suppressor gene. Therefore, variability of this gene might be implicated in the carcinogenesis of urinary bladder. The aim of the study was analysis of the association between the g.33590184 G>A (rs1207568), g.33634983 C>T (rs564481), g.33628193 G>C (rs9527025) polymorphisms of the Klotho gene and bladder cancer risk. Materials and methods: The study included 96 patients diagnosed with transitional cell carcinoma of the bladder (TCC) and 114 healthy, cancer-free individuals. Three selected polymorphisms were typed by PCR with confronting two-pair primers (PCR-CTPP) and Real Time PCR with TaqMan probes. Results: The GA and AA genotypes of the rs1207568 polymorphism increased the risk of bladder cancer (OR = 1.86, 95% CI [1.04-3.33], p = 0.03 and OR = 6.58, 95% CI [1.27-34.02], p = 0.01, respectively). Individuals who were heterozygous and homozygous for the A variant had 2.10-fold higher risk of bladder cancer (OR = 2.10, 95% CI [1.20-3.65], p = 0.009). On the other hand, heterozygous subjects and homozygous carriers of the wild-type allele (G) had a decreased bladder cancer risk (OR = 0.19, 95% CI [0.04-0.95], p = 0.043). Also, the occurrence of bladder cancer was positively correlated with the presence of the GC genotype of the rs9527025 polymorphism (OR = 2.84, 95% CI [1.57-5.15], p = 0.0001). Conclusions: Two polymorphisms of Klotho gene (rs1207568 and rs9527025) may play a role in susceptibility to bladder cancer.
Wstęp: Rak pęcherza moczowego jest najczęściej występującym nowotworem układu moczowego w Polsce. Sugeruje się, że gen Klotho może pełnić funkcje genu supresorowego. W związku z tym, polimorfizm genu Klotho może mieć wpływ na proces transformacji nowotworowej pęcherza moczowego. Celem przedstawionych badań był analiza związku pomiędzy występowaniem wybranych polimorfizmów pojedynczych nukleotydów g.33590184 G>A (rs1207568), g.33634983 C>T (rs564481), g.33628193 G>C (rs9527025) a ryzykiem zachorowania na raka pęcherza moczowego. Materiały i metody: Do badań włączono 96 pacjentów ze zdiagnozowanym przejściowokomórkowym rakiem pęcherza moczowego (TCC; transitional cell carcinoma) oraz 114 osób zdrowych, u których nie stwierdzono choroby nowotworowej. Występowanie trzech wybranych polimorfizmów analizowano przy użyciu techniki PCR z dwiema parami przeciwstawnych starterów (PCR-CTPP; PCR with confronting two-pair primers) oraz metody Real Time PCR z sondami fluorescencyjnymi TaqMan. Wyniki: Genotypy GA i AA polimorfizmu rs1207568 wpływają na wzrost ryzyka zachorowania na przejściowokomórkowego raka pęcherza moczowego (OR = 1,86, 95% PU [1,04-3,33], p = 0,03 oraz OR = 6,58, 95% CI [1,27-34,02], p = 0,01, odpowiednio). U osób będących heterozygotami lub homozygotami pod względem allela A wykazano ponad 2-krotnie wyższe ryzyko zachorowania na raka pęcherza moczowego (OR = 2,10, 95% PU [1,20-3,65], p = 0,009). Natomiast w przypadku nosicieli allela G, w układzie homozygotycznym lub heterozygotycznym, obserwowano spadek ryzyka zachorowania na badany nowotwór (OR = 0,19, 95% PU [0,04-0,95], p = 0,043). W przypadku polimorfizmu rs952705 wykazano, że genotyp GC zwiększa ryzyko zachorowania na przejściowokomórkowego raka pęcherza moczowego (OR = 2,84, 95% PU [1,57-5,15], p = 0,0001).Wnioski: Dwa spośród badanych polimorfizmów genu Klotho (rs1207568 i rs9527025) mogą mieć wpływ na predyspozycję do zachorowania na przejściowokomórkowego raka pęcherza moczowego.
Źródło:
Folia Medica Lodziensia; 2012, 39, 2; 189-205
0071-6731
Pojawia się w:
Folia Medica Lodziensia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Polymorphism of the porcine growth hormone gene and its linkage to microsatellites S0083 and S0090
Autorzy:
Korwin-Kossakowska, A
Pierzchala, M.
Kuryl, J.
Zwierzchowski, L.
Cymerowska-Prokopczyk, I.
Siadkowska, E.
Powiązania:
https://bibliotekanauki.pl/articles/2043894.pdf
Data publikacji:
1999
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
pig
gene
polymorphism
microsatellite
Sus scrofa
linkage
growth hormone
Źródło:
Journal of Applied Genetics; 1999, 40, 2; 85-91
1234-1983
Pojawia się w:
Journal of Applied Genetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Plasminogen activator inhibitor-1 (PAI-1) gene 4G/5G promoter polymorphism is not associated with breast cancer.
Autorzy:
Błasiak, Janusz
Smolarz, Beata
Powiązania:
https://bibliotekanauki.pl/articles/1044431.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
gene polymorphism
PAI-1 gene
prognostic marker
plasminogen activator inhibitor-1 (PAI-1)
breast cancer
Opis:
The antigen content of plasminogen activator inhibitor-1 (PAI-1) in primary breast cancer tissue extracts may be of strong prognostic value: high levels of PAI-1 in tumors predict poor prognosis for patients. The gene encoding PAI-1 is highly polymorphic and an insertion (5G)/deletion (4G) polymorphism in the PAI-1 gene promoter (the 4G/5G polymorphism), may have functional significance in PAI-1 expression. In the present work the distribution of genotypes and frequency of alleles of the 4G/5G polymorphism in subjects with breast cancer were investigated. Tumor tissues were obtained from 100 postmenopausal women with node-negative and node-positive ductal breast carcinoma with uniform tumor size. Blood samples from age matched healthy women served as control. The 4G/5G polymorphism was determined by PCR amplification using the allele specific primers. The distribution of the genotypes of the 4G/5G polymorphism in both control and patients did not differ significantly (P > 0.05) from those predicted by the Hardy-Weinberg distribution. There were no differences in the genotype distributions and allele frequencies between node-positive and node-negative patients. The 4G/5G polymorphism may not be linked with elevated level of PAI-1 observed in breast cancer and therefore may not be associated with appearance and/or progression of breast cancer.
Źródło:
Acta Biochimica Polonica; 2000, 47, 1; 191-199
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Transferrin receptor levels and polymorphism of its gene in age-related macular degeneration
Autorzy:
Wysokinski, Daniel
Danisz, Katarzyna
Pawlowska, Elzbieta
Dorecka, Mariola
Romaniuk, Dorota
Robaszkiewicz, Jacek
Szaflik, Marta
Szaflik, Jerzy
Blasiak, Janusz
Szaflik, Jacek
Powiązania:
https://bibliotekanauki.pl/articles/1039085.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
AMD
gene polymorphism
iron
oxidative stress
TFRC
transferrin receptor
Opis:
The aim of the present study was to investigate the association of age related macular degeneration (AMD) risk with some aspects of iron homeostasis: iron concentration in serum, level of soluble transferrin receptor (sTfR), and transferrin receptor (TFRC) genetic variability. Four hundred and ninety one AMD patients and 171 controls were enrolled in the study. Restriction fragment length polymorphism PCR was employed to genotype polymorphisms of the TFRC gene, and colorimetric assays were used to determine the level of iron and sTfR. Multiple logistic regression was applied for all genotype/allele-related analyses and the ANOVA test for iron and sTfR serum level comparison. We found that the genotypes and alleles of the c.-253G > A polymorphism of the TFRC gene were associated with AMD risk and this association was modulated by smoking status, AMD family history, living environment (rural/urban), body mass index and age. The levels of sTfR was higher in AMD patients than controls, whereas concentrations of iron did not differ in these two groups. No association was found between AMD occurrence and the p.Gly142Ser polymorphism of the TRFC gene. The results obtained suggest that transferrin receptor and variability of its gene may influence AMD risk.
Źródło:
Acta Biochimica Polonica; 2015, 62, 2; 177-184
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Lack of Association Between the 135G/C Rad51 Gene Polymorphism and the Risk of Colorectal Cancer Among Polish Population
Autorzy:
Mucha, Bartosz
Przybyłowska-Sygut, Karolina
Dziki, Łukasz
Dziki, Adam
Sygut, Andrzej
Majsterek, Ireneusz
Powiązania:
https://bibliotekanauki.pl/articles/1396683.pdf
Data publikacji:
2012-07-01
Wydawca:
Index Copernicus International
Tematy:
polymorphism
135G/C RAD51 gene
colorectal cancer
Opis:
One of the major causes of carcinogenesis is loss of genome stability. RAD51 in process of homologous recombination (HR) played crucial role in maintenance integrity of genome through initiate of DNA double strand breaks repair. Presence of single nucleotide polymorphism (SNP) in RAD51 gene could change the capacity of DNA repair and altered the response to damaging agents. Research on potential impact of genetic variability on development and progression CRC may contribute to setting new genetic markers or/and determined individual susceptibility to CRC.The aim of the study. This study was designed to evaluate the effect of 135 G/C (rs1801320) RAD51 polymorphism located in the 5' untraslated region on the risk and progression of CRC.Material and methods. The subjects consisted of histologically confirmed colorectal cancer (n = 200) and controls (n = 200) with lack of previous history of cancer. The distribution of genotypes was determined by restriction fragment length polymorphism PCR (RFLP - PCR). Statistical analysis was based on multivariate regression model.Results and conclusion. Our study reveal no significance association of 135 G/C RAD51 polymorphism with occurrence and progression of colorectal cancer.
Źródło:
Polish Journal of Surgery; 2012, 84, 7; 358-362
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-50 z 343

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