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Wyświetlanie 1-15 z 31
Tytuł:
Przesunięcie netto lipidów między plazmą a błoną krwinek czerwonych
Sdvig lipidov (netto) mezhdu plazmojj i obolochkojj ehritrocutov
The plasma - erythrocyte membrane lipids (netto) shift
Autorzy:
Badzio, T.
Solecki, A.
Powiązania:
https://bibliotekanauki.pl/articles/2189513.pdf
Data publikacji:
1973
Wydawca:
Polskie Towarzystwo Diagnostyki Laboratoryjnej
Źródło:
Diagnostyka Laboratoryjna; 1973, 09, 1-2; 95-98
0867-4043
Pojawia się w:
Diagnostyka Laboratoryjna
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Decreased erythrocyte ghost membrane fluidity as a result of lipid composition changes in plasma of adult Insulin-dependent diabetics
Obniżona płynność błon arytrocytarnych jako wynik zmian ilościowych lipidów osocza w cukrzycy insulnozależnej u ludzi dorosłych
Autorzy:
Watała, Cezary
Bryszewska, Maria
Leyko, Wanda
Powiązania:
https://bibliotekanauki.pl/articles/945083.pdf
Data publikacji:
1986
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Źródło:
Acta Universitatis Lodziensis. Folia Biochimica et Biophysica; 1986, 5
0208-614X
Pojawia się w:
Acta Universitatis Lodziensis. Folia Biochimica et Biophysica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Interactions between the gene products of pma1 encoding plasma membrane H^+-ATPase, and pdr1 controlling multiple drug resistance in Saccharomyces cereivisiae
Autorzy:
Ułaszewski, Stanisław
Powiązania:
https://bibliotekanauki.pl/articles/1045440.pdf
Data publikacji:
1993
Wydawca:
Polskie Towarzystwo Biochemiczne
Źródło:
Acta Biochimica Polonica; 1993, 40, 4; 487-496
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of hypothermia on the insulin - receptor interaction in adipose plasma membranes
Autorzy:
Torlinska, T
Mackowiak, P.
Nogowski, L.
Kozlik, J.
Powiązania:
https://bibliotekanauki.pl/articles/70049.pdf
Data publikacji:
1995
Wydawca:
Polskie Towarzystwo Fizjologiczne
Tematy:
lipolysis
receptor
insulin
hypothermia
fat cell
lipid metabolism
epididymal adipose tissue
carbohydrate
rat
normothermia
hypoinsulinemia
adipose plasma membrane
Źródło:
Journal of Physiology and Pharmacology; 1995, 46, 3
0867-5910
Pojawia się w:
Journal of Physiology and Pharmacology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Age dependent changes of insulin receptors in rat tissues
Autorzy:
Torlinska, T.
Mackowiak, P.
Nogowski, L.
Hryniewiecki, T.
Witmanowski, H.
Perz, M.
Madry, E.
Nowak, K.M.
Powiązania:
https://bibliotekanauki.pl/articles/69323.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Fizjologiczne
Tematy:
plasma membrane
hyperglycemia
hyperinsulinemia
aging
heart
insulin receptor
liver
rat
tissue
skeletal muscle
hormone
Źródło:
Journal of Physiology and Pharmacology; 2000, 51, 4,2
0867-5910
Pojawia się w:
Journal of Physiology and Pharmacology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Apoptosis in the gastric mucosa: molecular mechanisms, basic and clinical implications
Autorzy:
Szabo, I.
Tarnawski, A.S.
Powiązania:
https://bibliotekanauki.pl/articles/69195.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Fizjologiczne
Tematy:
plasma membrane
molecular mechanism
epithelial cell
gastric gland
gastric mucosa
mucosal surface
stomach
apoptosis
Helicobacter pylori
clinical implication
Źródło:
Journal of Physiology and Pharmacology; 2000, 51, 1
0867-5910
Pojawia się w:
Journal of Physiology and Pharmacology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Plasma membrane Ca2+ -ATPase in excitable and nonexcitable cells.
Autorzy:
Żylińska, Ludmiła
Soszyński, Mirosław
Powiązania:
https://bibliotekanauki.pl/articles/1044284.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
calcium homeostasis
brain
erythrocytes
plasma membrane Ca2+ -ATPase
Opis:
There is a significant number of data confirming that the maintenance of calcium homeostasis in a living cell is a complex, multiregulated process. Calcium efflux from excitable cells (i.e., neurons) occurs through two main systems - an electrochemically driven Na+/Ca2+ exchanger with a low Ca2+ affinity (K0.5 = 10-15 μM), and a plasmalemmal, specific Ca2+-ATPase, with a high Ca2+ affinity (K0.5 < 0.5-1 μM), whereas in nonexcitable cells (i.e., erythrocytes) the calcium pump is the sole system responsible for the extrusion of calcium ions. The plasma membrane Ca2+-ATPase (PMCA) is a ubiquitously expressed protein, and more than 26 transcripts of four PMCA genes are distributed in a tissue specific manner. Differences in the structure and localization of PMCA variants are thought to correlate with specific regulatory properties and may have consequences for proper cellular Ca2+ signaling. The regulatory mechanisms of calcium pump activity have been studied extensively, resulting in a new view of the functioning of this important molecule in the membranes.
Źródło:
Acta Biochimica Polonica; 2000, 47, 3; 529-539
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mitochondrial uncoupling does not influence the stability of the intracellular signal activating plasma membrane calcium channels.
Autorzy:
Zabłocki, Krzysztof
Makowska, Agnieszka
Duszyński, Jerzy
Powiązania:
https://bibliotekanauki.pl/articles/1044178.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Jurkat cells
store-operated calcium entry
mitochondrial uncoupling
thapsigargin
Opis:
The effects of various concentrations of thapsigargin, a specific inhibitor of Ca2+-ATPase in the endoplasmic reticulum (ER) membrane, on calcium homeostasis in lymphoidal T cells (Jurkat) were investigated. Preincubation of these cells suspended in nominally calcium-free medium with 0.1 μM thapsigargin resulted in a complete release of Ca2+ from intracellular calcium stores. When the medium was supplemented with 3 mM CaCl2 the cells maintained constantly elevated level of cytosolic Ca2+. However, thapsigargin applied at lower concentration produced only a partial depletion of the stores. For example, in the cells pretreated with 1 nM thapsigargin and suspended in calcium-free medium approximately 75% of the calcium content was released from the intracellular stores. The addition of 3 mM CaCl2 to such cell suspension led to a transient increase in cytosolic calcium concentration, followed by a return to a lower steady-state. This phenomenon, related to the refilling of the ER by Ca2+, allowed to estimate the half-time for the process of cell recovery after activation of store-operated calcium channels. By this approach we have found that carbonyl cyanide m-chlorophenylhydrazone, which has been documented to inhibit calcium entry into Jurkat cells, does not influence the stability of the intracellular signal involved in the activation of store-operated calcium channels.
Źródło:
Acta Biochimica Polonica; 2001, 48, 1; 157-161
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Accelerated and natural ageing processes change the properties of plasma membrane in Norway spruce (Picea abies (L.) Karst.) seeds during storage
Autorzy:
Nowakowska, J
Rakowski, K.
Powiązania:
https://bibliotekanauki.pl/articles/41613.pdf
Data publikacji:
2002
Wydawca:
Polska Akademia Nauk. Instytut Dendrologii PAN
Tematy:
plasma membrane
Norway spruce
natural aging process
Picea abies
vitality
vigor
storage
seed
Opis:
The present study examines the mechanism of natural and accelerated ageing processes in Norway spruce (Picea abies [L.] Karst.) seeds stored at low temperature for one (control) and eight years. The analyses of vitality, electrolyte leakage, protein composition and activity of the proton-pump ATPase (P-ATPase, EC.3.6.1.35) in plasma membrane of Norway spruce seeds have been investigated. Seeds collected in 1999 from northeastern Poland have been treated with accelerated ageing method and compared to the seeds of the same provenance, collected in 1992 (control). The vigor and the vitality of the Norway spruce seeds depend on the age of seeds. After 6 days of experiment both samples of seeds (artificially aged seeds and control) expressed the same percentage of germination and similar electrolyte leakage. Analysis of protein composition in the extracts showed an increased amount of some low molecular-weight proteins in artificially and naturally aged seeds compared to the control. Our results indicate similar level of P-ATPase activity in natural, artificially aged and control seeds. This suggests that natural ageing process can involve changes in plasma membrane protein composition but does not affect the P-ATPase activity.
Źródło:
Dendrobiology; 2002, 47 Supplement
1641-1307
Pojawia się w:
Dendrobiology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Plasma membrane rafts and chaperones in cytokine/ STAT signaling.
Autorzy:
Sehgal, Pravin
Powiązania:
https://bibliotekanauki.pl/articles/1043429.pdf
Data publikacji:
2003
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
cytokine receptors
chaperones
fever
heat shock protein 90 (HSP90)
signal transducers and activators of transciption (STATs)
caveolin
lipid rafts
Opis:
We and others have recently obtained data suggesting that cytokine-STAT signaling in many different cell-types is a chaperoned pathway initiated at the level of specialized plasma membrane microdomains called "rafts" (the "raft-STAT signaling hypothesis"). These findings are of broad significance in that all cytokines and growth factors initiate signaling in target cells by interacting with respective cell-surface receptors. The new data suggest that raft microdomains represent the units of function at the cell-surface through which ligand-stimulated STAT signaling is initiated. Moreover, recent evidence shows the involvement of chaperone proteins in regulating the STAT signaling pathway. These chaperones include the human homolog of the tumorous imaginal disc 1 protein (hTid1) which associates with Janus kinase 2 (JAK2) at the level of the plasma membrane, heat shock protein 90 (HSP90) which associates with STAT3 and STAT1 proteins in caveolin-1-containing raft and cytoplasmic complexes, and glucose regulated protein 58 (GRP58/ER-60/ERp57), a thiol dependent protein-disulfide isomerase, found in association with STAT3 "statosome" complexes in the cytosol and in the raft fraction. We suggest a function of the HSP90 chaperone system in preserving IL-6/STAT3 signaling in liver cells in the context of fever. The identification and function of protein partners associated with specific STAT species in rafts and in cytosolic complexes, and in the efficient departure of cytokine-activated STATs from the cytosolic face of rafts towards the cell nucleus are now areas of active investigation.
Źródło:
Acta Biochimica Polonica; 2003, 50, 3; 583-594
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A possible involvement of plasma membrane NAD(P)H oxidase in the switch mechanism of the cell death mode from apoptosis to necrosis in menadione-induced cell injury.
Autorzy:
Niemczyk, Edyta
Majczak, Anna
Hallmann, Anna
Kędzior, Jakub
Woźniak, Michał
Wakabayashi, Takashi
Powiązania:
https://bibliotekanauki.pl/articles/1041516.pdf
Data publikacji:
2004
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
menadione
NADPH oxidase
necrosis
superoxide
apoptosis
Opis:
The effects of inhibitors of plasma membrane NADPH oxidase on menadione-induced cell injury processes were studied using human osteosarcoma 143B cells. The intracellular level of superoxide in the cells treated with menadione for 6 h reached a maximum followed by an abrupt decrease. The population of apoptotic cells detected by Annexin V and propidium iodide double staining also reached its maximum at 6 h of menadione-treatment while that of necrotic cells increased continuously reaching 90% of the total population at 9 h of the treatment. Pretreatment of the cells with inhibitors of NADPH oxidase, including diphenyliodonium chloride, apocynin, N-vanillylnonanamide and staurosporine was effective in lowering the menadione-induced elevations of superoxide, and also in the suppression of the switch of the cell death mode from apoptosis to necrosis in menadione-treated cells except for the case of staurosporine. These results strongly suggest that superoxide generated by NADPH oxidase, besides that generated by the mitochondria, may contribute to the remarkable increase in the intracellular level of superoxide in the cells treated with menadione for 6 h resulting in the switch from apoptosis to necrosis, although a direct evidence of the presence of active and inactive forms of NADPH oxidase in control and menadione-treated 143B cells is lacking at present.
Źródło:
Acta Biochimica Polonica; 2004, 51, 4; 1015-1022
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mikrodomeny błony komórkowej miejscem zapoczątkowania szlaków sygnałowych przez immunoreceptory
Plasma membrane rafts as centers for signal transduction by immunoreceptors
Autorzy:
Kwiatkowska, Katarzyna
Sobota, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1199437.pdf
Data publikacji:
2004
Wydawca:
Polskie Towarzystwo Przyrodników im. Kopernika
Opis:
Sphingolipids and cholesterol of the plasma membrane self-organize into microdomains named rafts. They are 30-50 nm dynamic lipid assemblies that facilitate local accumulation of GPI-anchored proteins and Src family protein tyrosine kinases in their outer and inner leaflet, respectively. It has been demonstrated in the last five years that immunoreceptors, including TCR, BCR and Fc receptors, associate with rafts upon binding of their polyvalent ligands. Within rafts, tyrosine residues of the receptor signaling sequence ITAM are phosphorylated by kinases of the Src family, being convert simultaneously into docking sites for Syk and Zap70 tyrosine kinases. The joint activity of the Src and Syk/Zap70 families of tyrosine kinases triggers signaling cascades leading eventually to proper responses of cells. An important feature of this process is a fusion of rafts of various composition bringing together molecules required for formation of signaling complexes at activated immunoreceptors.
Źródło:
Kosmos; 2004, 53, 2; 113-122
0023-4249
Pojawia się w:
Kosmos
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Plasma membrane homing of tissue nonspecific alkaline phosphatase under the influence of 3-hydrogenkwadaphnin, an antiproliferative agent from Dendrostellera lessertii
Autorzy:
Sadeghirizi, Akram
Yazdanparast, Razieh
Powiązania:
https://bibliotekanauki.pl/articles/1041081.pdf
Data publikacji:
2007
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
alkaline phosphatase
anti-proliferative
Dendrostellera lessertii
Opis:
Several mammalian enzymes are anchored to the outer surface of the plasma membrane by a covalently attached glycosylphosphatidylinositol (GPI) structure. These include acetylcholinesterase, alkaline phosphatase (AP) and 5'-nucleotidase among other enzymes. Recently, it has been reported that these membrane enzymes can be released into the serum by the GPI-dependent phospholipase D under various medical disturbances such as cancer and/or by chemical and physical manipulation of the biological systems. Treatment of MCF-7 cells with two consecutive effective concentrations of 3-hydrogenkwadaphnin (3-HK, 3 nM) for 48 h enhanced membrane AP activity by almost 330% along with a 40% reduction in the AP activity of the cell culture medium. In addition, our data indicate that 3-HK is capable of inducing mainly the tissue-nonspecific alkaline phosphatase (TNAP) isoenzyme, along with enhancing its thermostability. These findings, besides establishing a correlation between the antiproliferative activity of 3-HK and the extent of plasma membrane AP activity, might assist in the development of new diagnostic tools for following cancer medical treatments.
Źródło:
Acta Biochimica Polonica; 2007, 54, 2; 323-329
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Response of maize, pea and radish roots to allelochemical stress
Autorzy:
Gmerek, J.
Politycka, B.
Powiązania:
https://bibliotekanauki.pl/articles/19185.pdf
Data publikacji:
2011
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
plant response
maize
pea
radish
root
allelochemical stress
p-coumaric acid
ferulic acid
lipid peroxidation
lipoxygenase
plasma membrane
sweet maize
Opis:
We examined whether allelochemical stress leads to increased lipoxygenase activity in roots of sweet maize (Zea mays L. ssp. saccharata), pea (Pisum sativum L.) and radish (Raphanus sativum L. var. radicula). The lipoxygenase activity of soluble and membrane-bound fractions was assessed in roots after exposure to ferulic and p-coumaric acids. Lipid peroxidation and membrane injury were determined as indicators of stress. Increased lipoxygenase activity of both studied fractions was followed by lipid peroxidation and plasma membrane injury. The results suggest the key role of lipoxygenase in plasma membrane injury during allelochemical stress caused by administration of hydroxycinnamic acids.
Źródło:
Acta Biologica Cracoviensia. Series Botanica; 2011, 53, 1
0001-5296
Pojawia się w:
Acta Biologica Cracoviensia. Series Botanica
Dostawca treści:
Biblioteka Nauki
Artykuł
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