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Tytuł:
Interdisciplinary treatment and rehabilitation based on the point electrostimulation in the patient with hemangioma mass on the floor of the oral cavity
Autorzy:
Zomkowska, Edyta
Sowa, Mariusz
Barczewska, Monika
Misiowiec, Piotr
Kukwa, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1399614.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
tongue hemangiomas
arteriography
surgical treatment
embolisation
rehabilitation
point electrostimulation
palatogram
Opis:
Tongue hemangiomas usually originate from the vascular system. They are spherical in shape and often result in a significant mass increase and swelling of the tissues in the vicinity of the lips (the so-called cavernous angioma) or the gums and tongue (the so-called vascular granuloma). The hemangiomas in the area of the oral cavity often cause the swelling of the neighboring tissues what makes it difficult to talk, swallow, take and chew food. The conservative treatment is associated with removal of a lesion. The surgical treatment should be preceded by vascular diagnostics (arteriography) that helps to assess the extent and intensity of tumor vasculature. The arterial tumor with rich vascularization is treated by the endovascular embolization of the vessels feeding to tumor. The embolization is performed among other things to reduce bleeding during surgery Generation of voiced speech in changed anatomical conditions requires searching for new, substitute places of articulation. It is not easy due to the fact that many tissues have been deformed after the surgery (including partial glossectomy). The decision about how to conduct speech rehabilitation is made with help of, for example, linguograms. The most important in the early phase of the rehabilitation is to initiate the functions of the reflex arc by, among others, stimulation or induced contraction of the muscles involved in the act of swallowing and speech. In the case of this patient, the rehabilitation was performed with methods of point electrostimulation. The use of point electrostimulator contributed to shorter necessary time with the gastroesophageal tube and, thus, gave the possibility of self-feeding to the patient and resulted in a more efficient rehabilitation of active speech.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2019, 8, 1; 44-48
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of selected oral cavity microbiota – risk factors of management complications in patients with masticatory system disorders
Autorzy:
Zawadzki, P.J.
Perkowski, K.
Starosciak, B.
Dybicz, M.
Baltaza, W.
Pionkowski, K.
Chomicz, L.
Powiązania:
https://bibliotekanauki.pl/articles/6035.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Parazytologiczne
Opis:
The retrospective analysis of data on oral cavity clinical status in relation to microbiota species composition is presented. The research regards patients of different age, with and without congenital malformation, pretreatment assessed for occurrence of pathological changes in the masticatory system. Samples of the swabs collected from each patient (from dental plaque, periodontium and dental pockets) were used for identification of oral protozoans in wet slides and stained preparations; additionally, transmission electron microscope examination was performed. The material was used for in vitro cultures to identify bacteria strains. Clinically, intensity of tissue deteriorations was higher in patients with a congenital disease. Alive Trichomonas tenax and Entamoeba gingivalis, species with confirmed pathogenic impact on oral cavity and neighboring structures, were detected with higher prevalence in older patients. Enterococci, Staphylococcus aureus, various Enterobacteriaceae were more frequently detected in patients with somatic and mental retardations; in mouths of those patients, Klebsiella pneumonia and Pseudomonas aeruginosa opportunistic strains occurred. Masticatory system abnormalities favor colonization of oral cavity by exogenous species and dissemination of infections, especially dangerous for patients with congenital diseases. Oral microbiota assessment and preventive measures may be helpful to avoid subsequent peri-surgery complications.
Źródło:
Annals of Parasitology; 2016, 62, 1
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Identification of infectious microbiota from oral cavity environment of various population group patients as a preventive approach to human health risk factors
Autorzy:
Zawadzki, Paweł J.
Perkowski, Konrad
Starościak, Bohdan
Baltaza, Wanda
Padzik, Marcin
Pionkowski, Krzysztof
Chomicz, Lidia
Powiązania:
https://bibliotekanauki.pl/articles/987130.pdf
Data publikacji:
2016
Wydawca:
Instytut Medycyny Wsi
Tematy:
infectious microbiota
oral cavity
risk of peri-surgery complications
preventive approach
Opis:
Introduction and objective. This study presents the results of comparative investigations aimed to determine microbiota that can occur in the oral environment in different human populations. The objective of the research was to identify pathogenic oral microbiota, the potential cause of health complications in patients of different population groups. Materials and method. The study included 95 patients requiring dental or surgical treatment; their oral cavity environment microbiota as risk factors of local and general infections were assessed. Results. In clinical assessment, differences occurred in oral cavity conditions between patients with malformations of the masticatory system, kidney allograft recipients and individuals without indications for surgical procedures. The presence of various pathogenic and opportunistic bacterial strains in oral cavities were revealed by direct microscopic and in vitro culture techniques. Conclusions. Colonization of oral cavities of patients requiring surgical treatment by the potentially pathogenic bacteria constitutes the threat of their spread, and development of general infections. Assessment of oral cavity infectious microbiota should be performed as a preventive measure against peri-surgical complications.
Źródło:
Annals of Agricultural and Environmental Medicine; 2016, 23, 4
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ethanol influence on gingival fibroblasts - a real-time in vitro study
Autorzy:
Wyganowska-Świątkowska, M.
Nowak, A.
Paszyńska, E.
Grzech-Leśniak, K.
Powiązania:
https://bibliotekanauki.pl/articles/2081937.pdf
Data publikacji:
2018
Wydawca:
Instytut Medycyny Wsi
Tematy:
alcohol
oral cavity
gingival fibroblasts
Opis:
Introduction. Alcohol consumption is the world’s third largest risk factor for disease and disability. According to the WHO report from 2011: 71% of urban respondents ty and 77% of rural respondents admit to alcohol consumption]. Lower socio-economic status and educational levels result in a greater risk of alcohol-related injury, disease and death. Alcohol is a common component of many medicines, as well as an ingredient in many oral hygiene home products. Mouthwashes containing alcohol are considered to inhibit wound healing in the oral cavity. Due to the fact that many different results are described for different concentrations of alcohol at different times, an attemptwas made to visualise the direct impact of 7.2% and 22% alcohol on human gingival fibroblasts. Materials and method. PANsystem 2000 was used for visualisation of the reaction of human gingival fibroblasts isolated from gingiva on ethanol in 2 different concentrations. PANsys 3000 is a multi-system fully-automated cell culture device used for in vitro culture and to study a variety of cell lines under conditions similar to in vivo. Observations were carried out for 48 hours since alcohol addition. Pictures were taken in a continuous process at 5 minute intervalds and combined into a film. Results. Both contamination of 7.2% and 22% ethyl alcohol negatively affected morphology and cell proliferation. Addition of ethanol at a concentration 7.2% enabled cells to regain their ability to divide and recover normal morphology after 10 hours; changes caused by 22% ethanol, however, were irreversible. Conclusions. The obtained results suggest that daily usage of 7.2% alcohol contained in mouthwashes is non-toxic for gingival fibroblasts, and could be recommended after periodontal surgery.
Źródło:
Annals of Agricultural and Environmental Medicine; 2018, 25, 4; 647-650
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Epidemiological analysis of 22 patients with congenital bleeding diathesis hospitalized in the Department of Maxillofacial Surgery in Lublin, Poland, 2008–2013
Autorzy:
Wojciechowicz, Jolanta
Gawęda, Anna
Kasprzak, Patryk
Sokołowska, Bożena
Tomaszewski, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/972591.pdf
Data publikacji:
2016
Wydawca:
Instytut Medycyny Wsi
Tematy:
haemophilia
replacement therapy
oral cavity surgeries
Opis:
Introduction. Haemophilia A and B are congenital bleeding disorders caused by coagulation factor VIII or IX deficiency. Haemophilia A and B occur in men, like all qualities dependent on genes linked to gender, whereas women are asymptomatic carriers of the gene. The most dangerous manifestations of severe haemophilia include spontaneous haemorrhages into the joints, muscles and body cavities, haematuria and potentially very dangerous intracranial haemorrhages are also quite frequent. The most common manifestations in the region of the maxillofacial skeleton and oral cavity are recurring bleedings from the nose and the gums after dental extractions, as well as extensive haemorrhages from wounds after surgical procedures. Objective. The aim of the study was the analysis of epidemiologic case records of 22 patients affected by various types of haemophilia, admitted to Maxillofacial Surgery Department at Medical University in Lublin, Poland, during 2008–2013. Results. The most numerous group constituted patients diagnosed with Haemophilia A, followed by patients with von Willebrand disease and Haemophilia B, aged 21–40 years. The main cause of hospital admission was the need to perform complex oral cavity sanation. The patients were treated with factor VIII or Factor IX, FEIBA or Heamate P, depending on the type and severity of bleeding diathesis.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2016, 10, 1; 45-49
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The role of obesity in modifying the course of periodontal diseases
Autorzy:
Walis, M.
Kłosek, S.
Powiązania:
https://bibliotekanauki.pl/articles/1916503.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
overweight
obesity
periodontal diseases
oral cavity
Opis:
Overweight and obesity constitute a serious social problem. They are considered hazards of developed countries. Overweight and obesity affect both adults and children. Numerous researches on the negative impact of obesity on the condition of oral cavity have been conducted. The purpose of this paper is to provide a review of the most recent data published and noted in PubMed database between 2007 and 2014, on the association between overweight and obesity and oral diseases, including caries and periodontal diseases, as well as to discuss their mechanisms. The majority of studies discussed in this paper demonstrate the existence of an association between obesity and the health of the oral cavity. An association between overweight and obesity expressed as various anthropometric indices, and oral cavity conditions should be the subject of further prospective studies.
Źródło:
Progress in Health Sciences; 2014, 4, 1; 195-199
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Diagnostyka molekularna rzęsistków jamy ustnej u pacjentów z HIV
Molecular diagnosis of oral cavity trichomonads in HIV patients.
Autorzy:
Turkowicz, M.
Tomaszewska, D.
Cielecka, D.
Powiązania:
https://bibliotekanauki.pl/articles/2146450.pdf
Data publikacji:
2004
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
diagnostyka molekularna
Trichomonas tenax
rzesistek policzkowy
pacjenci
jama ustna
HIV
Opis:
The occurrence of trichomonads in oral cavity of HIV patients is not well known. HIV patients often suffer from oral lesions (candidiosis, advanced caries) and it remains unclear if any oral parasites can affect that, therefore the aim of the study was verification of species that can occur in HIV patients” oral cavity. Diagnosis of oral trichomonads can be performed by conventional methods (microscopic observation of wet and stained preparations and cultivation) but these are time consuming and insufficient for proper species differentiation, therefore in order to detect and identify species of parasites precisely, molecular methods such as PCR (Polymerase Chain Reaction) and sequencing of its product, were applied. 54 HIV patients (18 females and 36 males at the age of 20-54) were examined. All of them were addicted to intravenous drugs for at least 6 years. Saliva, smears and spittle samples were collected and used for cultivation, preparations and molecular diagnosis. For PCR amplification a pair of primers (T1 and T2) specific for ITS 1 — 5.8 SrRNA — ITS 2 region was designed. The oral trichomonads were detected in saliva samples of 3 HIV patients; these were males at the age of 25, 27 and 44. The identification of species by PCR and sequencing of the PCR products showed the trichomonads belonging to Trichomonas tenax. Infection of HIV patients’ oral cavity caused by T. tenax is rather related with inflammatory processes than with the immunosuppression of these patients but should be considered as a potential factor in pathogenesis of oral disorders in immunosuppressed patients.
Źródło:
Wiadomości Parazytologiczne; 2004, 50, 2; 181-186
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Oral cavity status of long-term hemodialized patients vs. their socio-economic status
Autorzy:
Trzcionka, Agata
Twardawa, Henryk
Mocny-Pachońska, Katarzyna
Tanasiewicz, Marta
Powiązania:
https://bibliotekanauki.pl/articles/2085564.pdf
Data publikacji:
2020-05-15
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
chronic diseases
socio-economic status
end-stage chronic kidney disease
oral health
hemodialysis
health maintenance
Opis:
BackgroundThe chronic kidney disease, blood hypertension and diabetes are recognized as civilization diseases that affect more and more people. The probability of encountering a patient suffering from these diseases is increasing. As such, it appears crucial to better understand the specific dental needs of such groups of patients. The aim of the work was to assess the oral hygiene status and the needs of patients suffering from the end-stage chronic kidney disease, arterial hypertension or/and diabetes.Material and MethodsTwo hundred and twenty eight patients were included in the research. One hundred and eighty patients were hemodialized in Diaverum dialysis stations and 48 patients were from the Conservative Dentistry with Endodontics Clinic of the Academic Centre of Dentistry in Bytom, Silesian Medical University in Katowice, and from the Dentistry Division of the Arnika Clinic in Zabrze, and were not not diagnosed with any of the diseases mentioned. The research scheme was divided into 3 parts, consisting of an analysis of the general health socio-economic status, a survey and an assessment of oral health.ResultsThe patients who were not suffering from any of the discussed diseases were more aware of how to properly perform hygienic procedures. Most of the patients from both the control and examined groups were not using any rinsing solutions. A higher percentage of patients in the control group was using dental floss, changing their toothbrush every 3 months and brushing their teeth for ≥2 min. The Aproximal Plaque Index and the Oral Hygiene Index-Simplified values in the control group were significantly lower in comparison to the examined group.ConclusionsThe socio-economic status of hemodialized patients was low, which in most cases was a result of the difficulties in starting a job. Due to the lower standards of life, the neglect of oral hygiene maintenance and its consequences could be observed.
Źródło:
Medycyna Pracy; 2020, 71, 3; 279-288
0465-5893
2353-1339
Pojawia się w:
Medycyna Pracy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Fungi of the genus Rhodotorula isolated from the oral cavity of oncologic patients with colorectal cancer
Autorzy:
Troska, Piotr
Sucharzewska, Ewa
Dynowska, Maria
Ejdys, Elżbieta
Powiązania:
https://bibliotekanauki.pl/articles/972215.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
Rhodotorula
oral cavity
enzymes
colorectal cancer
Opis:
This paper concerns the frequency of occurrence and enzymatic activity of fungi of the genus Rhodotorula isolated from the oral cavity of patients with colorectal cancer. Swabs from the oral cavity were subjected to standard mycological diagnostic procedures; enzymatic activity of the fungi was evaluated using and API Zym test by BioMereux. The fungi of the genus Rhodotorula were noted in 22.5% positive isolates originating from women and 25.7% positive isolates originating from men. They included mono-species isolates of: Rh. glutinis, Rh. minuta, Rh. mucilaginosa and two-species isolates: Rh. minuta + Candida dubliniensis, Rh. mucilaginosa + C. albicans and Rh. mucilaginosa + Saccharomyces cerevisiae. The enzymatic activity of the isolated fungi was evaluated as high and very high in the case of acidic and alkaline phosphatase, esterase lipase, lipase, as well as leucine, valine and cysteine arylamidase. The highest values were determined in Rh. mucilaginosa with co-occurrence of C. albicans and Rh. minuta with co-occurrence of C. dubliniensis. In the ontosphere of oncologic patients, the increasingly frequent appearance of the species of fungi with high and very high enzymatic activity indicates the progressing risk posed by opportunistic forms, which includes Rhodotorula species.
Źródło:
Annals of Parasitology; 2017, 63, 1; 57-62
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The necessity of evaluation of prosthetic treatment of missing teeth caused by hard tissues of oral cavity diseases and injuries for students of Bialystok universities
Ocena potrzeb leczenia protetycznego braków zębowych spowodowanych schorzeniami twardych tkanek jamy ustnej oraz urazami wśród studentów białostockich uczelni
Autorzy:
Taraszkiewicz-Sulik, Katarzyna
Kosińska, Klaudia
Mosiej, Julia Krystyna
Gołębiewska, Maria
Powiązania:
https://bibliotekanauki.pl/articles/1195391.pdf
Data publikacji:
2016
Wydawca:
Instytut Medycyny Wsi
Opis:
Introduction and objective. The main aim of the research was to estimate the need for prosthetic treatment among students of three Bialystok universities and to analyse the factors that may influence this need. Materials and method. The research involved a group of 380 students attending three different Bialystok universities: Medical University of Bialystok, University of Bialystok and Bialystok University of Technology. The questionnaire comprised of 9 questions indicating such problems as: missing teeth, reasons for lack of the teeth, kind of treatment used or reasons why it was not administered, was used to collect the data. A Chi2 test was used to analyse relationships between investigated factors. Results. Missing teeth were reported in 109 of the surveyed (28.7%). Orthodontic reasons and caries as a second reason were the most common causes for missing teeth occurrence. 19 students (17.4%) with missing teeth had prosthetic appliances. Those who had not undergone prosthetic treatment gave orthodontic reasons (21.4%) as the cause or subjective lack of need for treatment (18.4%). The occurrence of missing teeth did not statistically differ between universities. Conclusions. The research showed a quantity drop in missing teeth occurrences when compared to research by other authors. Although it was observed that the number of missing teeth is decreasing, there are still too few people who fill them properly, which may suggest insufficient awareness of tooth loss consequences.
Wprowadzenie i cel pracy. Liczne badania wskazują, że już młode osoby z powodu braków w uzębieniu potrzebują interwencji protetycznej. Jednak niska świadomość na temat negatywnych zmian zachodzących w układzie stomatognatycznym już po utracie jednego zęba powoduje, iż leczenie protetyczne często nie jest podejmowane. Celem naszej pracy była ocena potrzeb leczenia protetycznego wśród studentów trzech białostockich uczelni. Materiał i metoda. Badaniem objęto grupę 380 studentów z trzech białostockich uczelni: Uniwersytetu Medycznego, Uniwersytetu w Białymstoku oraz Politechniki. Posłużono się ankietą własnego autorstwa składającą się z 9 pytań, które dotyczyły miedzy innymi obecności braków w uzębieniu, przyczyn ich wystąpienia, czy też rodzaju zastosowanego leczenia. Do analizy związków między badanymi cechami wykorzystano test Chi2.. Wyniki. Braki w uzębieniu zgłosiło 109 ankietowanych (28,7%). Najczęstszą przyczyną ich wystąpienia okazały się wskazania ortodontyczne, a następnie próchnica. 19 studentów (17,4%) z brakami zębowymi posiadało uzupełnienia protetyczne. Osoby, które nie podjęły się leczenia protetycznego, za najczęstszą przyczynę takiego stanu wskazały względy ortodontyczne (24,1%) lub też subiektywny brak potrzeby leczenia (18,4%). Występowanie braków w uzębieniu nie było statystycznie różne pomiędzy uczelniami. Wnioski. Wyniki pracy ukazały spadek występowania braków zębowych w porównaniu do wcześniejszych badań. Mimo, iż obserwuje się spadek braków zębowych, to niewiele jest osób uzupełniających te braki, co może świadczyć o niedostatecznej świadomości dotyczącej następstw płynących z utraty zębów.
Źródło:
Medycyna Ogólna i Nauki o Zdrowiu; 2016, 22(51), 2
2083-4543
Pojawia się w:
Medycyna Ogólna i Nauki o Zdrowiu
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Assessment of Candida spp. frequency in the oral cavity ontocenosis of healthy individuals in different age groups
Autorzy:
Szymańska, Jolanta
Wójtowicz, Agnieszka
Malm, Anna
Powiązania:
https://bibliotekanauki.pl/articles/972336.pdf
Data publikacji:
2016
Wydawca:
Instytut Medycyny Wsi
Tematy:
fungi
Candida spp
Candida albicans
Opis:
Introduction. Among the microorganisms colonizing the oral cavity ontocenosis, an important role is played by fungi: mainly yeast-like fungi of the Candida genus, and especially by the species C. albicans. Objective. The aim of this study was to evaluate the frequency of oral colonization by Candida species in healthy individuals of different age groups, and to identify the species of the isolates. Materials and method. The fungi were isolated from the oral cavities of 654 healthy individuals of both genders, representing different age groups, and the species of the isolates were determined. Initial identification of the yeast-like fungi was made based on the macroscopic appearance of the colonies on Sabouraud’s medium, and the growth of coloured colonies on ChromAgar Candida medium. API 20 C AUX microtest (bioMerieux) was used to identify the most frequently found species of Candida spp. Results. The frequency of Candida isolation from the oral cavity ontocenosis in healthy individuals of different age groups was assessed as 30.6%. The oral cavity ontocenosis was colonized mainly by the yeast-like fungi of C. albicans species: they were found in 24.5% of the tested population, while the frequency of oral cavity colonization by non-albicans Candida spp. was 6.1%. Seven species of non-albicans Candida spp. were identified: C. glabrata, C. inconspicua, C. famata, C. tropicalis, C. parapsilosis, C. lusitaniae, and C. kefyr. Conclusions. In the Polish population, 30.6% of the oral cavity ontocenosis is colonized by Candida yeast-like fungi, while C. albicans is the fungus that colonizes oral cavity ontocenosis most frequently. The frequency of oral cavity ontocenosis colonization with Candida spp (including C. albicans) increases with age.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2016, 10, 2; 91-94
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Gait changes in patients after reconstruction of facial bones with fibula and iliac crest free vascularized flaps
Autorzy:
Syczewska, M.
Krajewski, R.
Szczerbik, E.
Kalinowska, M.
Powiązania:
https://bibliotekanauki.pl/articles/949745.pdf
Data publikacji:
2018
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
wzorzec chodu
chirurgia rekonstrukcyjna
nowotwór złośliwy
jama ustna
gait pattern
reconstructive surgery
malignant tumour
oral cavity
Opis:
Patients with malignant tumours of the oral cavity require its surgical removal and reconstruction of the bone and soft tissues. The grafts are obtained either from leg (fibula) or pelvis (iliac crest). The removal of grafts from the locomotor apparatus can impair the gait. The aim of this study was to find out how the localization of donor site influences the gait pattern. Methods: Results obtained for 30 patients were analyzed (16 fibula graft, 14 iliac crest graft). Patients underwent instrumented gait analyses three times (VICON system): before surgery, 2–4 month after the surgery, and 4–8 months after the surgery. Results: In both groups several gait parameters were changed. Two parameters changed in both groups: gait speed and cadence. In patients receiving iliac crest graft the changed gait variables were: pelvic rotation, hip range in sagittal plane (operated side), knee range in sagittal plane (operated side), foot dorsiflexion in swing on both sides. In patients receiving fibula flap the changed gait variables were: tilt, range motion of the tilt, minimum hip flexion (operated side), time to maximum knee flexion (non-operated side), GGI (non-operated side) and step length (nonoperated side). Conclusions: The primary gait deviations occurring after surgery, and the compensatory mechanisms which subsequently arise depend on the localization of graft donor site. The results indicate that the patients in whom fibula flap was used have less problems with gait pattern after the surgery than the patients receiving iliac crest graft.
Źródło:
Acta of Bioengineering and Biomechanics; 2018, 20, 1; 185-190
1509-409X
2450-6303
Pojawia się w:
Acta of Bioengineering and Biomechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
An intraoral cone system for a Neptun 10PC linear accelerator
Autorzy:
Shokrani, P.
Soltani, P.
Powiązania:
https://bibliotekanauki.pl/articles/147656.pdf
Data publikacji:
2011
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
intraoral cone
oral cavity
electron boost
Opis:
Intraoral irradiation, the treatment choice for well defined oral-cavity tumors, is done using intraoral cone (IOC) systems. In this study, an IOC system was developed for a Neptun 10PC linac. Beam parameters necessary to plan an intraoral electron treatment were evaluated for two applicators, a flat and a beveled end. Measurements were performed using a Scanditronix (p-Si) diode field detector in a Scanditronix (RFAplus) 3-D (three-dimensional) water phantom. Percent depth dose distributions, beam profiles, and leakage dose distributions for the developed cone system are presented.
Źródło:
Nukleonika; 2011, 56, 4; 381-384
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ocena tabletek rozpadających się w jamie ustnej (ODTs) zawierających mikrosfery z losartanem potasu
Evaluation of orally disintegrating tablets (ODTs) containing microspheres with losartan potassium
Autorzy:
Sarecka-Hujar, Beata
Łyczak, Karol
Balwierz, Radosław
Jankowski, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1035227.pdf
Data publikacji:
2019
Wydawca:
Śląski Uniwersytet Medyczny w Katowicach
Tematy:
układy wielokompartmentowe
mikrosfery
losartan potasu
przedłużone uwalnianie
tabletki rozpadające się w jamie
ustnej
multicompartment systems
microspheres
potassium losartan
prolonged release
tablets disintegrating in the oral cavity
Opis:
Introduction: Multicompartment systems containing an active substance distributed among carriers (i.e. liposomes, microspheres, microcapsules, nanocapsules) open new possibilities for sustained or controlled drug release. Microspheres are monolithic, porous or smooth spherical particles, sized 1–500 μm, in which the drug substance is suspended, incorporated or emulsified in a polymer matrix. The aim of the study was to prepare microspheres containing losartan potassium and Eudragit L 100-55 as the matrix and then orally disintegrating tablets (ODTs) with the obtained microspheres. methods: Microspheres with drug:polymer ratios of 1:1 and 1:2 were obtained by the spray drying method under the following conditions: inlet temperature – 150°C, aspirator efficiency – 80% and pump efficiency – 10%. The morpho-logy and microsphere size were evaluated microscopically. Orally disintegrating tablets containing microspheres with losartan potassium were prepared by direct compression. The obtained tablets were evaluated according to the Farmakopea Polska X (FPX) requirements for this drug form. Statistical analysis was performed using Statistica 10.1. Results: The ODTs met the appearance, size and mass uniformity standards. The disintegration time of the obtained ODTs did not exceed the required 3 minutes. The release analysis of losartan potassium from the microspheres with the drug:polymer ratio of 1:1 in 0.1 M hydrochloric acid (HCl) showed that the largest amount of losartan (21%) was released in 60 minutes. After 120 minutes, the process was continued in artificial intestinal juice (pH = 6.8), in which losartan was completely released within 270 minutes. For the microspheres with the 1:2 ratio, we observed that the lar-gest amount of losartan (36%) was released in 90 minutes in 0.1 M HCl and further release in artificial intestinal juice showed a release of 99.43% of the active substance up to 300 minutes. Conclusion: The model microspheres containing losartan potassium can be used as an intermediate form of a drug to obtain ODTs.
Wprowadzenie: Układy wielokompartmentowe, w których dawka substancji leczniczej jest rozdzielona między nośniki (liposomy, mikrosfery, mikrokapsułki, nanokapsułki), otwierają nowe możliwości w uzyskaniu przedłużonego lub kontrolowanego uwalniania substancji leczniczej. Mikrosfery to monolityczne, porowate lub gładkie cząstki sferyczne o wielkości 1–500 µm, w których substancja lecznicza jest zawieszona, inkorporowana, rzadziej emulgowana w matrycy polimerowej. Celem pracy było sporządzenie mikrosfer zawierających losartan potasu i Eudragit L 100-55 jako matrycę polimerową, a następnie tabletek rozpadających się w jamie ustnej (orally disintegrating tablets – ODTs) z otrzymanymi mikrosferami. METODY: Mikrosfery o stosunku lek : polimer 1 : 1 i 1 : 2 otrzymano metodą suszenia rozpyłowego w następujących warunkach: temperatura na wlocie 150°C, wydajność aspiratora 80% oraz wydajność pompy 10%. Morfologia i wielkość mikrosfer oceniana była mikroskopowo. Tabletki zawierające mikrosfery z losartanem wykonano metodą tabletkowania bezpośredniego. Otrzymane ODTs oceniano zgodnie z wymogami Farmakopei Polskiej X (FPX) dla tej postaci leku. Analizę statystyczną przeprowadzono za pomocą programu Statistica 10.1. WYNIKI: Otrzymane ODTs spełniały normy wyglądu, wielkości i jednolitości masy. Czas rozpadu ODTs nie przekraczał wymaganych 3 min. W przypadku analizy uwalniania losartanu dla mikrosfer o stosunku lek : polimer 1 : 1 w 0,1 M roztworu kwasu solnego (HCl) maksymalna ilość substancji czynnej (21%) uwolniła się w 60 minucie. Po 120 min proces kontynuowano w sztucznym soku jelitowym (pH = 6,8), w którym losartan uwolnił się całkowicie w czasie 270 min. W przypadku mikrosfer 1 : 2 w 0,1 M HCl maksymalna ilość losartanu (36%) uwolniła się w 90 minucie, a dalsze uwalnianie w sztucznym soku jelitowym wykazało uwolnienie 99,43% substancji czynnej w czasie 300 min. WNIOSKI: Modelowe mikrosfery z losartanem potasu mogą być wykorzystane jako pośrednia postać leku do stworzenia ODTs.
Źródło:
Annales Academiae Medicae Silesiensis; 2019, 73; 36-42
1734-025X
Pojawia się w:
Annales Academiae Medicae Silesiensis
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Acid aspartate proteinase activity in fungal strains isolated from the oral cavity of patients with neoplasms
Autorzy:
Rozga, A.
Kurnatowska, A.J.
Loga, G.
Raczynska-Witonska, G.
Powiązania:
https://bibliotekanauki.pl/articles/841105.pdf
Data publikacji:
1998
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
endopeptidase
enzyme
cancer
Candida albicans
fungi
exopeptidase
oral cavity
proteolytic enzyme
patient
pathogenicity
fungal strain
acid aspartate proteinase
Candida
Źródło:
Annals of Parasitology; 1998, 44, 3
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 73

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